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The Ethics of Human Brain Organoid Transplantation in Animals. 动物脑类器官移植的伦理学。
IF 1.4 4区 哲学
Neuroethics Pub Date : 2023-01-01 Epub Date: 2023-10-04 DOI: 10.1007/s12152-023-09532-3
Masanori Kataoka, Christopher Gyngell, Julian Savulescu, Tsutomu Sawai
{"title":"The Ethics of Human Brain Organoid Transplantation in Animals.","authors":"Masanori Kataoka, Christopher Gyngell, Julian Savulescu, Tsutomu Sawai","doi":"10.1007/s12152-023-09532-3","DOIUrl":"10.1007/s12152-023-09532-3","url":null,"abstract":"<p><p>In this paper, we outline how one might conduct a comprehensive ethical evaluation of human brain organoid transplantation in animals. Thus far, ethical concerns regarding this type of research have been assumed to be similar to those associated with other transplants of human cells in animals, and have therefore not received significant attention. The focus has been only on the welfare, moral status, or mental capacities of the host animal. However, the transplantation of human brain organoids introduces several new ethical issues. Many of these are related to uncertainty regarding whether or not brain organoids might be conscious. While these concerns might not be immediately relevant, they warrant closer scrutiny. We discuss how various ethical issues are relevant to different stages of human brain organoid transplantation and can guide the ethical evaluation of research. Our examination would broaden the horizons of the debate on the transplantation of brain organoids.</p>","PeriodicalId":49255,"journal":{"name":"Neuroethics","volume":"16 3","pages":"27"},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41177335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges to the Diagnosis of Functional Neurological Disorder: Feigning, Intentionality, and Responsibility. 功能性神经障碍诊断的挑战:假装、意向性和责任。
IF 1.4 4区 哲学
Neuroethics Pub Date : 2023-01-01 Epub Date: 2022-10-22 DOI: 10.1007/s12152-022-09509-8
Xenos L Mason
{"title":"Challenges to the Diagnosis of Functional Neurological Disorder: Feigning, Intentionality, and Responsibility.","authors":"Xenos L Mason","doi":"10.1007/s12152-022-09509-8","DOIUrl":"https://doi.org/10.1007/s12152-022-09509-8","url":null,"abstract":"<p><p>The diagnosis of Functional Neurological Disorder (FND) requires differentiation from other neurologic diseases/syndromes, and from the comparatively rare diagnosis of feigning (Malingering and Factitious Disorder). Analyzing the process of diagnosing FND reveals a necessary element of presumption, which I propose underlies some of the uncertainty, discomfort, and stigma associated with this diagnosis. A conflict between the neurologist's natural social cognition and professional judgement (cognitive dissonance) can be understood by applying a framework originally designed for the determination of moral responsibility. Understanding the source of this cognitive dissonance may effect its alleviation, and in turn, allow more compassionate treatment of patients with FND.</p>","PeriodicalId":49255,"journal":{"name":"Neuroethics","volume":" ","pages":"2"},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40443810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Mental Integrity in the Attention Economy: in Search of the Right to Attention 注意力经济中的精神完整性:寻找注意力的权利
IF 1.4 4区 哲学
Neuroethics Pub Date : 2022-12-30 DOI: 10.1007/s12152-022-09514-x
Bartłomiej Chomański
{"title":"Mental Integrity in the Attention Economy: in Search of the Right to Attention","authors":"Bartłomiej Chomański","doi":"10.1007/s12152-022-09514-x","DOIUrl":"https://doi.org/10.1007/s12152-022-09514-x","url":null,"abstract":"","PeriodicalId":49255,"journal":{"name":"Neuroethics","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46655766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Brain Death: Still A Puzzle After All These Years 脑死亡:多年后仍是一个谜
IF 1.4 4区 哲学
Neuroethics Pub Date : 2022-12-15 DOI: 10.1007/s12152-022-09513-y
R. Maundrell
{"title":"Brain Death: Still A Puzzle After All These Years","authors":"R. Maundrell","doi":"10.1007/s12152-022-09513-y","DOIUrl":"https://doi.org/10.1007/s12152-022-09513-y","url":null,"abstract":"","PeriodicalId":49255,"journal":{"name":"Neuroethics","volume":"16 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2022-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53262636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Ethics of Memory Modification: Personal Narratives, Relational Selves and Autonomy 记忆修正的伦理:个人叙事、关系自我与自主性
IF 1.4 4区 哲学
Neuroethics Pub Date : 2022-11-28 DOI: 10.1007/s12152-022-09512-z
Przemysław Zawadzki
{"title":"The Ethics of Memory Modification: Personal Narratives, Relational Selves and Autonomy","authors":"Przemysław Zawadzki","doi":"10.1007/s12152-022-09512-z","DOIUrl":"https://doi.org/10.1007/s12152-022-09512-z","url":null,"abstract":"","PeriodicalId":49255,"journal":{"name":"Neuroethics","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2022-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46394988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Neurorights – Do we Need New Human Rights? A Reconsideration of the Right to Freedom of Thought 神经权利——我们需要新的人权吗?对思想自由权的再思考
IF 1.4 4区 哲学
Neuroethics Pub Date : 2022-11-23 DOI: 10.1007/s12152-022-09511-0
Nora Hertz
{"title":"Neurorights – Do we Need New Human Rights? A Reconsideration of the Right to Freedom of Thought","authors":"Nora Hertz","doi":"10.1007/s12152-022-09511-0","DOIUrl":"https://doi.org/10.1007/s12152-022-09511-0","url":null,"abstract":"","PeriodicalId":49255,"journal":{"name":"Neuroethics","volume":"16 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44687392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Neurorehabilitation of Offenders, Consent and Consequentialist Ethics 罪犯的神经康复、同意与后果主义伦理学
IF 1.4 4区 哲学
Neuroethics Pub Date : 2022-11-09 DOI: 10.1007/s12152-022-09510-1
Francisco Lara
{"title":"Neurorehabilitation of Offenders, Consent and Consequentialist Ethics","authors":"Francisco Lara","doi":"10.1007/s12152-022-09510-1","DOIUrl":"https://doi.org/10.1007/s12152-022-09510-1","url":null,"abstract":"","PeriodicalId":49255,"journal":{"name":"Neuroethics","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2022-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49392109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcranial Direct Current Stimulation (tDCS) in Pediatric Populations—– Voices from Typically Developing Children and Adolescents and their Parents 经颅直流电刺激（tDCS）在儿科人群中的应用——来自典型发育中的儿童、青少年及其父母的声音
IF 1.4 4区 哲学
Neuroethics Pub Date : 2022-11-05 DOI: 10.1007/s12152-022-09507-w
A. Sierawska, M. Splittgerber, V. Moliadze, M. Siniatchkin, A. Buyx
{"title":"Transcranial Direct Current Stimulation (tDCS) in Pediatric Populations—– Voices from Typically Developing Children and Adolescents and their Parents","authors":"A. Sierawska, M. Splittgerber, V. Moliadze, M. Siniatchkin, A. Buyx","doi":"10.1007/s12152-022-09507-w","DOIUrl":"https://doi.org/10.1007/s12152-022-09507-w","url":null,"abstract":"","PeriodicalId":49255,"journal":{"name":"Neuroethics","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2022-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49502530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Present and Emerging Ethical Issues with tDCS use: A Summary and Review 使用tDCS的当前和新出现的伦理问题:总结和回顾
IF 1.4 4区 哲学
Neuroethics Pub Date : 2022-10-17 DOI: 10.1007/s12152-022-09508-9
Parker Day, Jack Twiddy, Veljko Dubljević
{"title":"Present and Emerging Ethical Issues with tDCS use: A Summary and Review","authors":"Parker Day, Jack Twiddy, Veljko Dubljević","doi":"10.1007/s12152-022-09508-9","DOIUrl":"https://doi.org/10.1007/s12152-022-09508-9","url":null,"abstract":"","PeriodicalId":49255,"journal":{"name":"Neuroethics","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2022-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48529878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Engagement, Exploitation, and Human Intracranial Electrophysiology Research. 参与、开发和人类颅内电生理研究。
IF 1.4 4区 哲学
Neuroethics Pub Date : 2022-10-01 Epub Date: 2022-08-13 DOI: 10.1007/s12152-022-09502-1
Michelle T Pham, Nader Pouratian, Ashley Feinsinger
{"title":"Engagement, Exploitation, and Human Intracranial Electrophysiology Research.","authors":"Michelle T Pham,&nbsp;Nader Pouratian,&nbsp;Ashley Feinsinger","doi":"10.1007/s12152-022-09502-1","DOIUrl":"https://doi.org/10.1007/s12152-022-09502-1","url":null,"abstract":"<p><p>Motivated by exploitation concerns, we argue for the importance of participant engagement in basic human intracranial electrophysiology research. This research takes advantage of unique neurosurgical opportunities to better understand complex systems of the human brain, but it also exposes participants to additional risks without immediate therapeutic intent. We argue that understanding participant values and incorporating their perspectives into the research process may (i) help determine whether and to what extent research practices and the resulting distributions of risks and benefits constitute exploitation and (ii) contribute to building a brain research paradigm that is genuinely responsive to participant values. More broadly, we highlight the importance of paying attention to participant interests in non-therapeutic brain research.</p>","PeriodicalId":49255,"journal":{"name":"Neuroethics","volume":"15 3","pages":""},"PeriodicalIF":1.4,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451055/pdf/nihms-1833241.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33461548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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