Biopreservation and Biobanking最新文献

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Cord Blood Banking in Vietnam: Historical Perspective, Status, and Future Developments 2023. 越南的脐带血库:历史展望、现状和 2023 年的未来发展。
IF 1.6 4区 生物学
Biopreservation and Biobanking Pub Date : 2024-09-11 DOI: 10.1089/bio.2023.0139
Luong Thi Thanh-Ha,Phan Nhat-Tung,Chu Thi-Thao,Tran Van-Phuc,Nguyen The-Dung,Le Cong-Luc,Nguyen Kien-Thach,Nguyen Thi My-Trinh,Nguyen Van-Tinh
{"title":"Cord Blood Banking in Vietnam: Historical Perspective, Status, and Future Developments 2023.","authors":"Luong Thi Thanh-Ha,Phan Nhat-Tung,Chu Thi-Thao,Tran Van-Phuc,Nguyen The-Dung,Le Cong-Luc,Nguyen Kien-Thach,Nguyen Thi My-Trinh,Nguyen Van-Tinh","doi":"10.1089/bio.2023.0139","DOIUrl":"https://doi.org/10.1089/bio.2023.0139","url":null,"abstract":"","PeriodicalId":49231,"journal":{"name":"Biopreservation and Biobanking","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142208446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Supplementation of Rooster Semen Extender with Aqueous Extract of Urtica dioica for a Long Time Preservation by Low Temperature. 在公鸡精液扩展剂中添加荨麻水提取物以实现低温长时间保存
IF 1.6 4区 生物学
Biopreservation and Biobanking Pub Date : 2024-09-10 DOI: 10.1089/bio.2022.0165
Sina Naderi,Amjad Farzinpour,Asaad Vaziry,Abbas Farshad
{"title":"Supplementation of Rooster Semen Extender with Aqueous Extract of Urtica dioica for a Long Time Preservation by Low Temperature.","authors":"Sina Naderi,Amjad Farzinpour,Asaad Vaziry,Abbas Farshad","doi":"10.1089/bio.2022.0165","DOIUrl":"https://doi.org/10.1089/bio.2022.0165","url":null,"abstract":"The peroxidation of spermatozoa membrane phospholipids is a primary cause of irreversible changes in the preservation of avian semen. To address this issue, the objective of the present study was to assess the potential of Urtica dioica extracts in protecting avian spermatozoa during prolonged storage. Gas chromatography-mass spectroscopic techniques were employed to evaluate the bioactive compounds present in the aqueous and ethanolic extracts obtained from the aerial parts and roots of U. dioica. Semen samples were collected from 16 roosters twice a week and were diluted in Lake's extender containing different concentrations (0, 0.5, and 1 mg/100 mL) of the various extracts. Subsequently, the extended semen samples were cooled and stored at 5°C, and the sperm quality parameters were assessed at 0, 12, 24, and 36 hours of storage. The data from this experiment clearly demonstrate that the addition of nettle root aqueous extracts to the semen diluent, especially at a concentration of 0.5 mg/100 mL, resulted in a significant improvement in various sperm quality parameters. Notably, there were enhancements in total and progressive sperm motilities, viability, fertility, membrane integrity, acrosomal membrane integrity, and a reduction in malondialdehyde production in rooster semen stored in vitro for up to 36 hours. Interestingly, the present study reveals that the beneficial effects of the aqueous extracts from different parts of the nettle were supported not only by the conventional manual method but also by the computer-assisted sperm analysis system. This dual confirmation further emphasizes the positive impact of the aqueous extract on various sperm traits during cooled semen preservation. In conclusion, this study highlights the potential of U. dioica extracts, particularly the aqueous extract from nettle roots at a concentration of 0.5 mg/100 mL, in safeguarding avian spermatozoa during prolonged storage. The significant improvements in various sperm quality parameters and the validation of results through both manual and computer-assisted analysis methods provide strong evidence for the application of U. dioica extracts in avian breeding programs and artificial insemination practices.","PeriodicalId":49231,"journal":{"name":"Biopreservation and Biobanking","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142208445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality Assessment of Long-Term Cryopreserved Human Bone-Derived Marrow Mesenchymal Stromal Cell Samples: Experience from the Texas Heart Institute Biorepository and Biospecimen Profiling Core. 长期冷冻保存的人类骨衍生骨髓间充质基质细胞样本的质量评估:德克萨斯心脏研究所生物储存库和生物样本分析核心的经验。
IF 1.6 4区 生物学
Biopreservation and Biobanking Pub Date : 2024-09-10 DOI: 10.1089/bio.2023.0144
Lourdes Chacon Alberty,Madelyn King,Fernanda C P Mesquita,Camila Hochman-Mendez
{"title":"Quality Assessment of Long-Term Cryopreserved Human Bone-Derived Marrow Mesenchymal Stromal Cell Samples: Experience from the Texas Heart Institute Biorepository and Biospecimen Profiling Core.","authors":"Lourdes Chacon Alberty,Madelyn King,Fernanda C P Mesquita,Camila Hochman-Mendez","doi":"10.1089/bio.2023.0144","DOIUrl":"https://doi.org/10.1089/bio.2023.0144","url":null,"abstract":"In biomedical research, biorepositories are pivotal resources that safeguard and supply clinical samples for scientific investigators. Proper long-term cryopreservation conditions are essential to maintain biospecimen quality. In this study, we analyzed the efficacy of sample cryopreservation at the Texas Heart Institute Biorepository and Biospecimen Profiling Core (THI-BRC). Our assessments included a thorough review of internal processes, quality reports, and both internal and external audit outcomes. We examined the integrity of human bone marrow-derived multipotent mesenchymal stromal cells (BM-MSCs) that were cryopreserved for over 5 years. These samples originated from randomly selected clinical trial participants or commercially sourced cell lines. Parameters such as cell viability, DNA and RNA integrity, population doubling time, sterility, and BM-MSC-specific attributes such as surface antigen expression and differentiation potential were studied. BM-MSC samples cryopreserved for ∼6 months served as our control. Our results demonstrated that the 5-year cryopreserved samples maintained their integrity compared with the shorter-term stored control samples. Moreover, THI-BRC has met accreditation agency standards and has not received any repeated deficiencies over 7 years. Collectively, our findings affirm that THI-BRC's biospecimen storage protocols align with accepted standards as confirmed by the quality assessment of long-term stored clinical samples.","PeriodicalId":49231,"journal":{"name":"Biopreservation and Biobanking","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142208448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shipment of Glycerolized RBC Segments for Red Cell Concentrate Compatibility Testing. 装运甘油化红细胞片段,用于红细胞浓缩物兼容性测试。
IF 1.6 4区 生物学
Biopreservation and Biobanking Pub Date : 2024-09-10 DOI: 10.1089/bio.2023.0097
Carly Olafson,Tammy Ison,Carmela Pote,Nishaka William,Parth Patel,Gwen Clarke,Jason P Acker
{"title":"Shipment of Glycerolized RBC Segments for Red Cell Concentrate Compatibility Testing.","authors":"Carly Olafson,Tammy Ison,Carmela Pote,Nishaka William,Parth Patel,Gwen Clarke,Jason P Acker","doi":"10.1089/bio.2023.0097","DOIUrl":"https://doi.org/10.1089/bio.2023.0097","url":null,"abstract":"Background: Red cell concentrate (RCC) cryopreservation allows for long-term storage of RCCs with rare phenotypes. Currently, tubing segments are not produced for these frozen units. Pre-transfusion compatibility testing therefore requires thawing and deglycerolization of the whole unit. A study was conducted to demonstrate the feasibility of using segments for compatibility testing, including circumstances where segments would require shipment to a reference laboratory. Study Design and Methods: RCCs produced using the red cell filtration method from citrate-phosphate-dextrose whole blood collections were glycerolized (40%) at day 21 post-collection and segments were generated prior to freezing. Room temperature (RT, 18°C-20°C) or water bath (WB, 37°C) thawing of segments was performed prior to storage at RT or at refrigerated temperatures (cold, 1°C -6°C) for 0, 24, 48, or 72 hours followed by deglycerolization and hemolysis testing. Additional segments were thawed and shipped in temperature-controlled containers at either RT or 1°C -10°C for antibody screening. Results: Hemolysis and RBC recovery results did not show significant differences over the storage period or between thawing and storage conditions. RBC recovery ranged from 46% to 64%. Hemoglobin (Hb) recovery ranged from 56% to 96%; for RT-thawed segments, recovery was significantly higher at 24 hours and lower at 72 hours for RT storage compared with cold storage. WB-thawed, cold-stored segments had higher Hb recoveries at 48 hours. Phenotype assessment was successful for all segments regardless of thawing method or shipping condition. Discussion: The shipment of thawed segments containing glycerolized red cells is feasible for the purpose of conducting pretransfusion phenotype evaluations or pretransfusion compatibility checks.","PeriodicalId":49231,"journal":{"name":"Biopreservation and Biobanking","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142208447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving the Practice of Obtaining Informed Consent for Biobanking in Clinical Settings. 改进临床环境中获得生物库知情同意的实践。
IF 1.6 4区 生物学
Biopreservation and Biobanking Pub Date : 2023-10-01 Epub Date: 2022-09-29 DOI: 10.1089/bio.2021.0158
Laura Arregui Egido, María Villalobos-Quesada
{"title":"Improving the Practice of Obtaining Informed Consent for Biobanking in Clinical Settings.","authors":"Laura Arregui Egido,&nbsp;María Villalobos-Quesada","doi":"10.1089/bio.2021.0158","DOIUrl":"10.1089/bio.2021.0158","url":null,"abstract":"<p><p><b><i>Background:</i></b> Biobanks form key research support infrastructures that ensure the highest sample quality for scientific research. Their activity must align closely and proportionally to the interests of researchers, donors, and society. Informed consent (IC) is a central tool to guarantee the protection of donors' rights and interests. <b><i>Aim:</i></b> This study aimed to analyze the challenges of obtaining IC for biobanking in clinical settings and ways to improve this process. <b><i>Methods:</i></b> Biobank Bellvitge University Hospital HUB-ICO-IDIBELL in Barcelona received 8671 IC forms between 2017 and 2020. The mistakes that caused IC forms to be rejected by the Biobank were analyzed. In addition, interventions aimed at physicians to improve the IC process were evaluated through a calculation of the relative risk (RR). Finally, physicians who submitted samples to the Biobank, most of whom are involved in research activities, were surveyed about the barriers to collecting IC and how to improve this process. <b><i>Results:</i></b> During 2017-2020, 19.6% of IC forms were rejected. The most relevant cause of rejection was the use of outdated IC forms, followed by missing patient information or mistakes having been made by the physician. Evaluation of the rejection rates before and after interventions to improve the IC process suggests significant improvement (27.7% before interventions (January 2017-May 2018) compared to 9.6% after interventions (February-December 2020), RR 0.4 95% CI 0.34-0.47; <i>p</i> < 0.0001). According to the physicians, the most important barrier to collecting IC is the time constraint, and they consider digitalization as a viable solution. <b><i>Conclusions:</i></b> Our research offers a view of the less well-understood practical challenges that physicians and biobanks face when collecting IC in clinical settings. It suggests that, despite multiple challenges, continuous monitoring, training, and information programs for physicians are key to optimizing the IC process in clinical settings.</p>","PeriodicalId":49231,"journal":{"name":"Biopreservation and Biobanking","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40381951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Melatonin Supplementation for the Cryopreservation of Canine Sperm. 补充褪黑激素用于犬精子冷冻保存。
IF 1.6 4区 生物学
Biopreservation and Biobanking Pub Date : 2023-10-01 Epub Date: 2022-09-28 DOI: 10.1089/bio.2022.0009
Kianne Silva Monteiro, Naiara Cristina Motta, Ana Cláudia Pereira Cardoso, Stefânia Priscilla de Souza, Luis David Solis Murgas
{"title":"Melatonin Supplementation for the Cryopreservation of Canine Sperm.","authors":"Kianne Silva Monteiro,&nbsp;Naiara Cristina Motta,&nbsp;Ana Cláudia Pereira Cardoso,&nbsp;Stefânia Priscilla de Souza,&nbsp;Luis David Solis Murgas","doi":"10.1089/bio.2022.0009","DOIUrl":"10.1089/bio.2022.0009","url":null,"abstract":"<p><p>Antioxidants can be used in sperm cryopreservation protocols to reduce oxidative stress that occurs due to the cryopreservation process. The aim of this study was to evaluate the effects of melatonin supplementation on quality and oxidative stress parameters in cryopreserved canine sperm. Eighteen sperm ejaculates were collected from 6 Frenchie Bulldog males (3 collections per male). Sperm motility parameters, membrane integrity, and sperm morphology were analyzed before the cryopreservation process. The extender used in cryopreservation was composed of Tris-egg yolk and ethylene glycol 5% was added as a cryoprotectant. The cryoprotective medium was supplemented with 1.0, 1.5, 2.0, 2.5, and 3.0 mM melatonin, and the control group (without melatonin). Post-thaw sperm was evaluated as described for fresh sperm and oxidative stress parameters (lipid peroxidation, catalase, and superoxide dismutase). Post-thaw sperm motility parameters, membrane integrity, sperm morphology, and oxidative stress parameters did not differ (<i>p</i> > 0.05) among the control group and samples supplemented with melatonin. The results of this study showed that melatonin supplementation had no positive or negative effect on the parameters evaluated. Thus, it is suggested that different concentrations of melatonin be tested to assess its effectiveness as an antioxidant in the cryopreservation process in canine sperm.</p>","PeriodicalId":49231,"journal":{"name":"Biopreservation and Biobanking","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40380550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Initiative on Avian Primordial Germ Cell Cryobanking in Thailand. 泰国鸟类原始生殖细胞冷冻库倡议。
IF 1.6 4区 生物学
Biopreservation and Biobanking Pub Date : 2023-10-01 Epub Date: 2022-09-28 DOI: 10.1089/bio.2022.0043
Suparat Chaipipat, Kornkanok Sritabtim, Yanika Piyasanti, Sukumal Prukudom, Juthathip Jurutha, Vimolrat Phetpila, Rungthiwa Sinsiri, Jennarong Kammongkun, Amonrat Molee, Khongsak Thiangtum, Kannika Siripattarapravat
{"title":"Initiative on Avian Primordial Germ Cell Cryobanking in Thailand.","authors":"Suparat Chaipipat,&nbsp;Kornkanok Sritabtim,&nbsp;Yanika Piyasanti,&nbsp;Sukumal Prukudom,&nbsp;Juthathip Jurutha,&nbsp;Vimolrat Phetpila,&nbsp;Rungthiwa Sinsiri,&nbsp;Jennarong Kammongkun,&nbsp;Amonrat Molee,&nbsp;Khongsak Thiangtum,&nbsp;Kannika Siripattarapravat","doi":"10.1089/bio.2022.0043","DOIUrl":"10.1089/bio.2022.0043","url":null,"abstract":"<p><p><b><i>Background:</i></b> Biobanking the reproductive tissues or cells of animals preserves the genetic and reproductive ability of the species in long-term storage and promotes sharing of reproductive materials. In avian species, the primordial germ cell (PGC) is one of the most promising reproductive cells to be preserved in biobanks, due to self-renewal properties and direct access to the germ line mediated by PGC transfer. <b><i>Methods:</i></b> To conserve the genetic resource of local chicken breeds that are of conservation importance, we systematically isolated two types of pregonadal PGCs from chicken embryos-circulating and tissue PGCs. PGCs of individual embryos were separately isolated, cultured, and cryopreserved. Characteristics of cultured PGCs are described and evaluated. <b><i>Results:</i></b> The efficiency of PGC isolation from individual embryos was 98.9% (660/667). In most cases, both matching circulating and tissue PGC lines were isolated from the same embryo (68.2%, 450/660), whereas the remaining lines were from a single source, being either tissue (30.6%, 202/660) or circulating (1.2%, 8/660). Efficient PGC isolation and proliferation can be expected in cultures of circulating PGCs (68.7% and 64.3%, respectively) and tissue PGCs (97.8% and 80.7%, respectively). Following cryopreservation, recovered cells sustained PGC identities including expression of chicken vasa homolog and deleted in azoospermia-like proteins and migration ability to recipient embryonic gonads. Culture conditions equally supported proliferation of circulating and tissue PGCs from both sexes. Combining tissue PGC culture in the regimen prevented 30.3% loss of PGC cultures in the case where circulating PGC culture was ineffective. Cultured circulating and tissue PGCs were similar in morphology, but optimal culture characteristics were different. <b><i>Conclusion:</i></b> We applied the approach of PGC isolation from blood and tissue origins on a wide scale and demonstrated its efficiency for biobanking chicken PGCs. The workflow can be operated effectively almost year-round in a tropical climate. It was also described in ample and practical details, which are suitable for adoption or optimization in other conditions.</p>","PeriodicalId":49231,"journal":{"name":"Biopreservation and Biobanking","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40380549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The Application of Light-Assisted Drying to the Thermal Stabilization of Nucleic Acid Nanoparticles. 光辅助干燥在核酸纳米粒子热稳定中的应用。
IF 1.6 4区 生物学
Biopreservation and Biobanking Pub Date : 2022-10-01 Epub Date: 2022-09-02 DOI: 10.1089/bio.2022.0035
Phuong Anh Lam, Daniel P Furr, Allison Tran, Riley Q McKeough, Damian Beasock, Morgan Chandler, Kirill A Afonin, Susan R Trammell
{"title":"The Application of Light-Assisted Drying to the Thermal Stabilization of Nucleic Acid Nanoparticles.","authors":"Phuong Anh Lam,&nbsp;Daniel P Furr,&nbsp;Allison Tran,&nbsp;Riley Q McKeough,&nbsp;Damian Beasock,&nbsp;Morgan Chandler,&nbsp;Kirill A Afonin,&nbsp;Susan R Trammell","doi":"10.1089/bio.2022.0035","DOIUrl":"10.1089/bio.2022.0035","url":null,"abstract":"<p><p><b><i>Background:</i></b> Cold-chain storage can be challenging and expensive for the transportation and storage of biologics, especially in low-resource settings. Nucleic acid nanoparticles (NANPs) are an example of new biological products that require refrigerated storage. Light-assisted drying (LAD) is a new processing technique to prepare biologics for anhydrous storage in a trehalose amorphous solid matrix at ambient temperatures. In this study, LAD was used to thermally stabilize four types of NANPs with differing structures and melting temperatures. <b><i>Methods:</i></b> Small volume samples (10 μL) containing NANPs were irradiated with a 1064 nm laser to speed the evaporation of water and create an amorphous trehalose preservation matrix. Samples were then stored for 1 month at 4°C or 20°C. A FLIR C655 mid-IR camera was used to record the temperature of samples during processing. The trehalose matrix was characterized using polarized light imaging (PLI) to determine if crystallization occurred during processing or storage. Damage to LAD-processed NANPs was assessed after processing and storage using gel electrophoresis. <b><i>Results:</i></b> Based on the end moisture content (EMC) as a function time and the thermal histories of samples, a LAD processing time of 30 min is sufficient to achieve low EMCs for the 10 μL samples used in this study. PLI demonstrates that the trehalose matrix was resistant to crystallization during processing and after storage at 4°C and at room temperature. The native-polyacrylamide gel electrophoresis results for DNA cubes, RNA cubes, and RNA rings indicate that the main structures of these NANPs were not damaged significantly after LAD processing and being stored at 4°C or at room temperature for 1 month. <b><i>Conclusions:</i></b> These preliminary studies indicate that LAD processing can stabilize NANPs for dry-state storage at room temperature, providing an alternative to refrigerated storage for these nanomedicine products.</p>","PeriodicalId":49231,"journal":{"name":"Biopreservation and Biobanking","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603253/pdf/bio.2022.0035.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40353290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Barriers and Opportunities in Consent and Access Procedures in Low- and Middle-Income Country Biobanks: Meeting Notes from the BCNet Training and General Assembly. 中低收入国家生物库同意和访问程序中的障碍和机遇:BCNet 培训和大会的会议记录。
IF 1.6 4区 生物学
Biopreservation and Biobanking Pub Date : 2018-06-01 Epub Date: 2018-04-18 DOI: 10.1089/bio.2017.0081
Ma'n H Zawati, Anne Marie Tassé, Maimuna Mendy, Elodie Caboux, Michael Lang
{"title":"Barriers and Opportunities in Consent and Access Procedures in Low- and Middle-Income Country Biobanks: Meeting Notes from the BCNet Training and General Assembly.","authors":"Ma'n H Zawati, Anne Marie Tassé, Maimuna Mendy, Elodie Caboux, Michael Lang","doi":"10.1089/bio.2017.0081","DOIUrl":"10.1089/bio.2017.0081","url":null,"abstract":"<p><p>As biobanking research in low- and middle-income countries (LMICs) continues to grow, novel legal and policy considerations have arisen. Also, while an expansive literature has developed around these issues, the views and concerns of individual researchers in these contexts have been less actively studied. These meeting notes aim to contribute to the growing literature on biobanking in LMICs by communicating a number of challenges and opportunities identified by biobank researchers themselves. Specifically, we describe concerns that emerge in consent and access policy domains. First, we present a review of the literature on distinct policy and legal concerns faced in LMICs, giving special attention to the general absence of practitioner perspectives. From there, we outline and discuss considerations that were raised by meeting participants at a Biobank and Cohort Building Network (BCNet) Ethical, Legal, and Social Issues training program. We conclude by proposing that the unique perspectives of biobank researchers in LMICs should be given serious attention and further research on these perspectives should be conducted.</p>","PeriodicalId":49231,"journal":{"name":"Biopreservation and Biobanking","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39985772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Need for Research Infrastructures: A Narrative Review of Large-Scale Research Infrastructures in Biobanking. 对研究基础设施的需求:生物银行大规模研究基础设施的述评。
IF 1.6 4区 生物学
Biopreservation and Biobanking Pub Date : 2017-08-01 Epub Date: 2017-02-21 DOI: 10.1089/bio.2016.0103
Anthony Larsson
{"title":"The Need for Research Infrastructures: A Narrative Review of Large-Scale Research Infrastructures in Biobanking.","authors":"Anthony Larsson","doi":"10.1089/bio.2016.0103","DOIUrl":"https://doi.org/10.1089/bio.2016.0103","url":null,"abstract":"<p><strong>Background: </strong>Distributed Research Infrastructures are gaining political traction in Europe to facilitate scientific research. This development has gained particular momentum in the area of biobanking where cross-national attempts have been made toward harmonizing the biobanking standards across the European Union through the establishment of the organization BBMRI (BioBanking and Biomolecular Resources Research Infrastructure). BBMRI exists as separate national nodes across several European countries, although Sweden took on a pioneering role in its early stages. Thus, the Swedish node, BBMRI.se, was set up in 2009.</p><p><strong>Purpose: </strong>To document publications addressing the current debate on large-scale distributed medical and/or biobank Research Infrastructures and identify the most pressing issues discussed by these articles through a narrative review.</p><p><strong>Methods: </strong>The Web of Science (WOS) and PubMed databases were searched to find prior studies of large-scale medical Research Infrastructures, with no limits set with regard to study design and/or time period. All identified articles published up until March 2016 were included in the initial review.</p><p><strong>Results: </strong>A total of 145 articles were retrieved from WOS and PubMed, though merely 17 ultimately made it past the final exclusion criteria. About two-thirds of the articles listed a first author affiliated to a European country. The articles most commonly discussed the need for developing and expanding the use of \"infrastructures.\"</p><p><strong>Practical implications: </strong>The future of scientific research will call for a deeper and more widespread multidisciplinary collaboration. This will emphasize the need of research seeking to optimize the preconditions of securing sustainable scientific collaboration. Future investigators will thus need to understand the components and mechanisms of Research Infrastructures in addition to acquiring knowledge of how to build, manage, brand, and promote them as well.</p>","PeriodicalId":49231,"journal":{"name":"Biopreservation and Biobanking","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/bio.2016.0103","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39983323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
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