BMC Surgery最新文献

{"title":"Prognostic significance of lymphovascular invasion in pN0 stage gastric cancer: a propensity score matching analysis.","authors":"Xuguang Jiao, Yu Wang, Hao Fu, Yongning Liu, Jianjun Qu, Weihua Fu","doi":"10.1186/s12893-024-02705-8","DOIUrl":"10.1186/s12893-024-02705-8","url":null,"abstract":"<p><strong>Background: </strong>To explore the potential impact of lymphovascular invasion (LVI) on overall survival (OS) of pN0 stage gastric cancer (GC) after curative resection.</p><p><strong>Methods: </strong>A total of 497 GC patients who underwent curative gastrectomy and postoperative pathology proved negative lymph node metastasis between January 2015 and December 2018 in our center were enrolled in this study. All patients were divided into two groups according to the status of LVI. Their clinical and pathological features were compared and potential prognostic factors were analyzed using the propensity score matching analysis (PSM).</p><p><strong>Results: </strong>Ninety-nine (19.9%) patients had LVI. The presence of LVI was associated with significantly worse survival outcomes in both the overall and PSM cohorts (χ2 = 19.635, p < 0.001; χ2 = 9.367, p = 0.002). After PSM, data of 99 pairs of patients were extracted. Multivariate analysis revealed that number of examined lymph nodes (LNs), and LVI were independent predictors of OS (all p < 0.05). Following stratified analysis, patients with LNs 11-25 and those without LVI tended to have better OS than those with LVI (LNs 11-15: χ2 = 5.019, p = 0.025; LNs 16-25: χ2 = 11.876, p = 0.001).</p><p><strong>Conclusions: </strong>pN0 stage GC patients with LVI have poor prognosis. More than 15 lymph nodes need to be dissected to reduce the influence of LVI on the prognosis of pN0 stage GC patients.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"24 1","pages":"402"},"PeriodicalIF":1.6,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on risk factors of preoperative deep vein thrombosis in patients with lower limb fractures and construction and validation of risk prediction nomogram model.","authors":"Fan Zheng, Xiaobin Chen, Jianqiang Huang, Chen Lin","doi":"10.1186/s12893-024-02718-3","DOIUrl":"10.1186/s12893-024-02718-3","url":null,"abstract":"<p><strong>Background: </strong>To explore the correlation between the levels of D-dimer (D-D), fibrinogen (FIB), fibrinogen degradation products (FDP) and platelets (PLT) in peripheral blood of patients with lower limb fractures and the formation of deep vein thrombosis in lower limbs, and to establish a new thrombosis prediction model for patients with lower limb fractures.</p><p><strong>Methods: </strong>The patients were divided into DVT group and non DVT group according to whether there was deep vein thrombosis of the lower extremity. The differences in the levels of D-D, FIB, FDP and platelets between the two groups were analyzed and compared. ROC curve was used to evaluate the levels of D-D, FIB, FDP and PLT in the peripheral blood of patients with lower extremity fracture to predict the formation of deep vein thrombosis of the lower extremity. Logistic regression analysis was used to analyze the related risk factors of deep vein thrombosis, and the corresponding nomogram risk prediction model of lower limb deep vein thrombosis in patients with lower limb fractures was drawn according to the regression coefficient, which was verified by calibration curve, receiver operating characteristic curve (ROC) and consistency index (C-index).</p><p><strong>Results: </strong>The levels of D-D, FIB, FDP, and PLT in the DVT group were higher than those in the non DVT group, with statistical significance (P < 0.05); Moreover, FIB is superior to D-D, FDP, and PLT in predicting the risk of fractures and thrombosis, while PLT has the weakest predictive power. Multivariate logistic analysis showed that platelet, D-D, FIB and FDP were independent risk factors for deep vein thrombosis in patients with lower limb fractures (P < 0.05); Based on the independent risk factors mentioned above, the complex logistic regression formula was transformed into a visual column chart, and the consistency index (C-index) was 0.962 and 0.936, and the external verification C-index was 0.841. The calibration curve showed that the nomogram is in high agreement with the actual results. The AUC value of ROC curve indicated that the nomogram has high prediction value.</p><p><strong>Conclusions: </strong>The levels of D-D, FIB, FDP and PLT in peripheral blood of patients with lower limb fracture and DVT were significantly increased. Early monitoring of D-D, FIB, FDP and PLT levels in patients with lower limb fracture can effectively screen for lower limb deep vein thrombosis.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"24 1","pages":"408"},"PeriodicalIF":1.6,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a predictive model for postoperative major adverse cardiovascular events in elderly patients undergoing major abdominal surgery.","authors":"Adilai Kurexi, Rui Yan, Tingting Yuan, Zhaenhaer Taati, Maimaiti Mijiti, Dan Li","doi":"10.1186/s12893-024-02711-w","DOIUrl":"10.1186/s12893-024-02711-w","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the predictive value of a Short Physical Performance Battery (SPPB) for postoperative major adverse cardiovascular events(MACEs) in elderly patients undergoing major abdominal surgery and to develop a nomogram risk prediction model.</p><p><strong>Methods: </strong>A total of 427 elderly patients aged ≥ 65 years who underwent major abdominal surgery at our hospital between June 2023 and March 2024 were selected for the study, and 416 patients were ultimately included. The preoperative SPPB score was measured, and the patients were divided into two groups: a high SPPB group (≥ 10) and a low SPPB group (< 10). The subjects' clinical datasets and postoperative major adverse cardiovascular event (MACEs) occurrence data were recorded. LASSO regression analysis was performed to screen predictor variables and develop a nomogram risk prediction model for predicting MACEs. The area under the receiver operating characteristic (ROC) curve (AUC), calibration curve, and decision curve analysis (DCA) were used to evaluate the model's clinical efficacy.</p><p><strong>Results: </strong>The incidence of postoperative MACEs in elderly patients who underwent major abdominal surgery was 5%. LASSO regression analysis revealed that arrhythmia, creatine kinase, SPPB, anesthesia duration, age, intraoperative minimum heart rate, BMI, and coronary artery disease were significant predictors of MACEs. The nomogram risk prediction model based on SPPB and clinical indicators can better predict the occurrence of MACEs and can guide preoperative interventions and help to improve perioperative management.The decision curve indicated encouraging clinical effectiveness, the calibration curve demonstrated good agreement, and the area under the curve (AUC) was 0.852 (95% CI, 0.749-0.954).</p><p><strong>Conclusion: </strong>The nomogram risk prediction model based on SPPB and clinical indicators can better predict the occurrence of MACEs and can guide preoperative intervention and help to improve perioperative management.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"24 1","pages":"403"},"PeriodicalIF":1.6,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical application of multi-direction temporary Kapandji technique and volar locking plate fixation for type C distal radius fractures.","authors":"Wei Zhao, Kun-Xiu Song, Yong-Tao Liu, Bing-Dong Ma","doi":"10.1186/s12893-024-02725-4","DOIUrl":"10.1186/s12893-024-02725-4","url":null,"abstract":"<p><strong>Purpose: </strong>Achieving and maintaining an optimal reduction in partially or fully displaced intra-articular fractures, specifically Type C distal radius fractures, can present challenges. This study aims to retrospectively evaluate and summarize a method utilizing multi-directional temporary Kapandji technique in combination with the volar locking plate fixation for these fractures.</p><p><strong>Method: </strong>The study involved 15 patients diagnosed with Type C distal radius fractures who underwent surgery between January 2024 and April 2024. The procedure incorporated a multi-directional temporary Kapandji technique, followed by stable osteosynthesis using a volar locking plate system. The functional outcomes were assessed after 4 (2-6) months of follow-up using the modified Mayo wrist scoring system (MMWS). The MMWS is a rating system used to evaluate wrist function and pain, including pain, motion, grip strength.</p><p><strong>Results: </strong>All the patients incision healed within 2 weeks. All the fractures had uneventful union within 8-12 weeks. Based on the modified Mayo wrist scoring (MMWS) system, most patients showed good to excellent functional recovery.</p><p><strong>Conclusion: </strong>This reduction method proved to be both simple and replicable, enabling satisfactory alignment with minimal force. The volar locking plate system provided rigid and stable fixation.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"24 1","pages":"404"},"PeriodicalIF":1.6,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of a nomogram to predict the unfavorable outcomes in elderly patients undergoing lumbar fusion surgery for degenerative disease.","authors":"Peng Cui, Shuaikang Wang, Haojie Zhang, Peng Wang, Xiaolong Chen, Chao Kong, Shibao Lu","doi":"10.1186/s12893-024-02720-9","DOIUrl":"10.1186/s12893-024-02720-9","url":null,"abstract":"<p><strong>Objective: </strong>Failure to understand long-term quality of life and functional outcomes hinders effective decision making and prognostication. Therefore, the study aims to predict and analyse the unfavorable outcomes (FOs) in elderly patients undergoing lumbar fusion surgery.</p><p><strong>Methods: </strong>Consecutive 382 patients who underwent lumbar fusion surgery for lumbar degenerative disease from March 2019 to July 2022 were enrolled in this study. The risk factors were selected by the least absolute shrinkage and selection operator method (LASSO) regression. Then, a nomogram prediction model was established to predict unfavorable outcomes (UFOs) by using the risk factors selected from LASSO regression. The performance of the model was assessed by the calibration curve and receiver operating characteristic (ROC) curve. The decision curve analysis (DCA) and clinical impact curve (CIC) were used to evaluate the clinical utility of the model.</p><p><strong>Results: </strong>Finally, 147 of 382 patients showed UFOs. After splitting data in a 70 - 30 fashion, 267 patients were included in the training set. Ten potential risk factors were selected according to the LASSO regression, that identified the predictor to establish nomogram model. The area under the curve (AUC) value was 0.828, and the calibration curve gained from this prediction model suggested good predictive accuracy between the predicted probability and actual probability. In the validation set, the AUC for the model was 0.858. Likewise, the calibration curve gained from this prediction model suggested good predictive accuracy between the predicted probability and actual probability. And the results of DCA and CIC demonstrated that the model showed good clinical practicability in the validation set.</p><p><strong>Conclusion: </strong>This nomogram model has good predictive performance and clinical practicability, which could provide a certain basis for predicting UFOs in elderly patients undergoing lumbar fusion surgery.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"24 1","pages":"401"},"PeriodicalIF":1.6,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of an enhanced recovery programme on clinical outcomes and health-related quality of life after pancreaticoduodenectomy ad modum Whipple - an explorative and comparative single-centre study.","authors":"Thomas Andersson, My Engström, Johanna Wennerblom, Hanna Gyllensten, Kristofer Bjerså","doi":"10.1186/s12893-024-02667-x","DOIUrl":"10.1186/s12893-024-02667-x","url":null,"abstract":"<p><strong>Background: </strong>The introduction of enhanced recovery programmes (ERP) in pancreatic surgery has significantly improved clinical outcomes by decreasing the length of hospital stay, cost and complications without increasing readmissions and reoperations. To complement evidence on these outcomes, there is a need to explore patients' perspectives of a structured ERP. Therefore, this study aimed to explore the health-related quality of life (HRQoL) of patients before and after implementing ERP in pancreaticoduodenectomy ad modum Whipple (PD) at a regional surgical centre.</p><p><strong>Method: </strong>This was an explorative and comparative single-centre study in Sweden. A prospective cohort receiving ERP was included between October 2019 and December 2022 (n = 73) and was compared with a retrospective pre-ERP cohort between October 2011 and December 2013 (n = 65). EQ-5D, the European Organization for Research and Treatment of Cancer (EORCT) Quality of Life Questionnaire Cancer 30 items (QOL-C30), and EORCT Quality of Life Questionnaire pancreatic cancer module (QOL-PAN26) were collected preoperatively and at three and six months postoperatively. Demographic and clinical variables were collected from patient charts. Complications were expressed using the Clavien-Dindo Classification and the Comprehensive Complications Index (CCI).</p><p><strong>Results: </strong>There were no significant differences in general health, cancer- or disease-specific HRQoL between the pre-ERP and ERP cohorts. Length of stay was significantly shorter in the ERP cohort (16 vs. 11 days; p < 0.001). There was no significant difference in CCI.</p><p><strong>Conclusion: </strong>No significant differences were found in the HRQoL of patients who participated in an ERP compared to those who did not. However, a significant decrease in LoS was found when ERP was applied.</p><p><strong>Trial registration: </strong>Not applicable.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"24 1","pages":"407"},"PeriodicalIF":1.6,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transumbilical laparoendoscopic single-site surgery vs. multiport laparoscopic surgery for benign ovarian cysts: a retrospective cohort study.","authors":"Shuzhi Shan, Sufen Zhao, Xiao Wang","doi":"10.1186/s12893-024-02710-x","DOIUrl":"10.1186/s12893-024-02710-x","url":null,"abstract":"<p><strong>Background: </strong>Transumbilical laparoendoscopic single-site surgery (TU-LESS) has gained increasing attention due to the potential to maximize the benefits of laparoscopic surgery. This study aimed to compare outcomes of TU-LESS and multiport laparoscopic surgery (MLS) for the treatment of benign ovarian cysts.</p><p><strong>Methods: </strong>This retrospective cohort study included patients with benign ovarian cysts that were admitted to the Second Hospital of Hebei Medical University between September 2010 and September 2022. Inverse probability of treatment weighting (IPTW) approach weighting were used to compare outcomes of TU-LESS and MLS for benign ovarian cysts. The primary outcome was the rate of cystic content spillage.</p><p><strong>Results: </strong>A total of 528 patients with benign ovarian cysts were included and 236 (44.6%) patients underwent TU-LESS. The risk of cystic content spillage [relative risk (RR) = 4.37, 95% confidence interval (CI): 2.59-7.38), P < 0.001] and operation time (β = 4.94, 95% CI: 1.40-8.48, P = 0.017) during TU-LESS was significantly higher than that during MLS. While hospital stay (β=-0.10, 95% CI: -0.198 - -0.004, P = 0.043) during TU-LESS was significantly shorter. IPTW analyses yielded similar patterns of results. For ovarian cysts < 10 cm, the risk of cystic content spillage, operation time and EBL during TU-LESS was significantly higher than that during MLS (all P < 0.05). On the contrast, for ovarian cysts ≥ 10 cm, the risk of cystic content spillage, operation time and EBL during TU-LESS was significantly lower than that during MLS (all P < 0.05).</p><p><strong>Conclusions: </strong>TU-LESS had a significantly higher risk of cystic content spillage, longer operation time than MLS. While for ovarian cysts ≥ 10 cm, TU-LESS had a lower risk of cystic content spillage, shorter operation time, and less EBL than MLS. More experienced surgeons are needed to perform TU-LESS in benign ovarian cysts.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"24 1","pages":"399"},"PeriodicalIF":1.6,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Choice of open side affects clinical outcomes of unilateral open-door laminoplasty for inconsistent cervical ossification of the posterior longitudinal ligament.","authors":"Pan Qiao, Wen Zhang, Tiantong Xu, Rui Shao, Rong Tian","doi":"10.1186/s12893-024-02722-7","DOIUrl":"10.1186/s12893-024-02722-7","url":null,"abstract":"<p><strong>Background: </strong>The best open side for unilateral open-door laminoplasty (UODL) to treat inconsistent cervical ossification of the posterior longitudinal ligament (OPLL) needs to be identified.</p><p><strong>Methods: </strong>Thirty-one individuals with inconsistent OPLL who underwent UODL between January 2016 and December 2018 were retrospectively divided into two groups: when the side of the open door was consistent with the side of the larger ossification occupancy area, patients were placed in the Consistent group; when the side of the open door was contralateral to the side of the larger ossification occupancy area, patients were placed in the Contralateral group. The following parameters were evaluated: neck disability index (NDI) score, Japanese Orthopaedic Association (JOA) score, visual analog scale (VAS) score, postoperative laminoplasty opening width and angle, and spinal cord diameter ratio. Spinal cord shifts were also evaluated to compare the clinical results between the two groups.</p><p><strong>Results: </strong>Patient demographics and major problems did not differ significantly between the groups. Transient pain in the deltoid region was more frequent in the Consistent treatment group. The spinal cord diameter ratio, VAS and NDI scores, opening width, and angle in postoperative laminoplasty did not differ significantly between the two groups. The JOA scores improved in the Consistent group. The spinal cord diameter ratio and spinal cord shift were more significantly improved in the Consistent group.</p><p><strong>Conclusions: </strong>For inconsistent cervical OPLL, the open-door side that was consistent with a larger ossification occupancy area was preferred in UODL.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"24 1","pages":"405"},"PeriodicalIF":1.6,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662773/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic factors in patients with gastrointestinal perforation under the acute care surgery model : a retrospective cohort study.","authors":"Kiyoung Sung, Sanguk Hwang, Jaeheon Lee, Jinbeom Cho","doi":"10.1186/s12893-024-02687-7","DOIUrl":"10.1186/s12893-024-02687-7","url":null,"abstract":"<p><strong>Background: </strong>Gastrointestinal perforation (GIP) is a life-threatening condition that necessitates immediate surgical intervention. This study aims to identify prognostic factors in patients with GIP treated within a standardized acute care surgery (ACS) framework.</p><p><strong>Materials and methods: </strong>This single center retrospective cohort study analyzed patients diagnosed with GIP who underwent emergent surgery and were admitted to the intensive care unit between January 2013 and March 2023.</p><p><strong>Results: </strong>Among 354 patients, the mortality was 11%, and 38% of survivors experienced significant complications (Clavien-Dindo class III or higher). Independent prognostic factors for mortality included initial sequential organ failure assessment (SOFA) scores (at the time of admission or ACS activation), postoperative SOFA (p-SOFA) scores, and postoperative body temperatures. For morbidity, independent predictors were the extent of peritonitis, the open surgery, postoperative albumin levels, and p-SOFA scores. These factors showed significant predictive accuracy for patient outcomes, as evidenced by the area under the receiver operating characteristic curve. The Random Forest model identified p-SOFA scores and postoperative albumin levels as the most significant predictors for both survival and complications, with feature importances of 40.46% and 36.61% for survival, and 39.97% and 37.28% for complications, respectively. Postoperative body temperature also played a moderately important role, contributing 14.63% to mortality and 15.9% to morbidity predictions. Patients with a p-SOFA score ≥ 7, postoperative albumin ≤ 2, and body temperature ≤ 36 °C, as well as those with a p-SOFA score ≥ 10, albumin ≤ 2.9, and body temperature ≤ 36 °C, had a 100% mortality rate. These factors are critical indicators for predicting patient outcomes.</p><p><strong>Conclusion: </strong>It is crucial to establish a system that ensures rapid preoperative work-up, accurate surgical intervention, and evidence-based postoperative critical care. Implementing such a system and assessing patient outcomes after surgery using the identified factors could provide a more detailed evaluation.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"24 1","pages":"406"},"PeriodicalIF":1.6,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global surgery is stronger when infection prevention and control is incorporated: a commentary and review of the surgical infection landscape.","authors":"Chandler Hinson, Claire Kilpatrick, Kemal Rasa, Jianan Ren, Peter Nthumba, Robert Sawyer, Emmanuel Ameh","doi":"10.1186/s12893-024-02695-7","DOIUrl":"10.1186/s12893-024-02695-7","url":null,"abstract":"<p><p>Incorporating infection prevention and control (IPC) is crucial for strengthening global surgery, particularly in low- and middle-income countries (LMICs). This review article highlights the critical role IPC plays in ensuring equitable and sustainable surgical care, aligning with the Sustainable Development Goals (SDG) 3 and 10, which aim to promote health and reduce inequalities. Surgical site infections (SSIs) and other healthcare-associated infections (HAIs) disproportionately affect LMICs, where IPC infrastructure is often underdeveloped. Without robust IPC measures, surgeries in these regions can result in higher morbidity, mortality, and healthcare costs, exacerbating disparities in healthcare access and outcomes. Despite global efforts, such as the World Health Organization (WHO) Guidelines on the Prevention of Surgical Site Infections, IPC integration in surgical practices remains inconsistent, particularly in resource-constrained settings. More widespread adoption and implementation are necessary. By embedding IPC within global surgery frameworks, health systems can improve surgical outcomes, reduce costs, and enhance the resilience of healthcare systems. Effective IPC reduces extended hospital stays, limits the spread of antimicrobial resistance, and increases trust in surgical services. Moreover, the cost savings from preventing SSIs are substantial, benefiting both healthcare systems and patients by reducing the need for prolonged care and antibiotic treatments. This review article calls for greater integration of IPC measures in global surgery initiatives to ensure that surgical interventions are both life-saving and equitable. Strengthening IPC is not optional but essential for achieving the broader goals of universal health coverage and improving public health outcomes globally.</p>","PeriodicalId":49229,"journal":{"name":"BMC Surgery","volume":"24 1","pages":"397"},"PeriodicalIF":1.6,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}