Cell Journal最新文献

{"title":"Investigation of <i>SPOCD1</i> as A Suitable Diagnostic and Prognostic Biomarker in Various Common Cancer Types: Bioinformatics and Practical Analysis.","authors":"Samira Yavari, Maryam Naseroleslami, Maryam Peymani, Farshid Yekani, Niloufar Khayam Nekouei","doi":"10.22074/cellj.2024.2022401.1506","DOIUrl":"10.22074/cellj.2024.2022401.1506","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to assess whether Spen paralogue and orthologue C-terminal domain containing 1 (<i>SPOCD1</i>) gene expression could serve as a valuable prognostic and diagnostic biomarker in common cancers, drawing from insights in recent literature. We sought to verify this concept by utilizing data sourced from The Cancer Genome Atlas (TCGA) alongside clinical samples.</p><p><strong>Materials and methods: </strong>In this bioinformatics and experimental study, <i>SPOCD1</i> RNA-seq data from 12 common cancers were collected from TCGA Pan-Cancer Atlas using the R package \"TCGA BIOLINKS\" and normalized for analysis. Various analytical tools, including receiver operating characteristic (ROC) curves, Kaplan-Meier and Coxregression analyses, and pathway enrichment analysis via the molecular signatures database (MSigDB), were applied. Drug resistance/sensitivity correlations with <i>SPOCD1</i> expression were explored using the Gene Expression Omnibus (GEO) database. Clinical colorectal cancer (CRC) samples, including both colon and rectal malignant samples, were also evaluated.</p><p><strong>Results: </strong>The results showed elevated <i>SPOCD1</i> expression in most cancers (9/12), with notable prognostic value in COAD, HNSC, KICH, and LIHC, and a correlation with poor prognosis in COAD for disease-free survival. ROC curve analysis suggested SPOCD1 as a diagnostic biomarker in the majority of cases (7/12), although this pattern was inconsistent in clinical CRC samples. Pathway enrichment analysis revealed a strong correlation between <i>SPOCD1</i> expression and critical molecular pathways. Unlike former results, we found that SPOCD1 upregulated when interacting with PD-0325901. However, treating with Panobinostat led to downregulation. Both are as anticancer reagents.</p><p><strong>Conclusion: </strong>This study confirms the potential of <i>SPOCD1</i> as a diagnostic and prognostic biomarker in prevalent cancers. However, extensive clinical data, particularly for CRC, are required to validate its reliability. Different COAD subtypes may exhibit varying correlations with <i>SPOCD1</i> expression levels, underscoring the need for further investigation to fully understand its diagnostic and prognostic value.</p>","PeriodicalId":49224,"journal":{"name":"Cell Journal","volume":"26 5","pages":"309-319"},"PeriodicalIF":1.7,"publicationDate":"2024-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141767773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Latest Developments in Early Detection and Effective Treatment of Cancer: A Meeting Report.","authors":"Morvarid Ghattan, Niloofar Bajool, Mina Pahlavanneshan, Melika Zamanian, Sharif Moradi","doi":"10.22074/cellj.2024.2026689.1553","DOIUrl":"10.22074/cellj.2024.2026689.1553","url":null,"abstract":"<p><p>Despite a lower estimated rate of cancer incidence in Iran compared to the global average, the trend is unfortunately increasing. This necessitates the implementation of early detection of cancer and targeted therapies to effectively treat various types of cancer. Therefore, the 5th \"International Royan Cancer Conference: From Bench to Bedside\" was held to focus on critical cancer-related aspects such as gene- and cell therapy, immunotherapy, oligonucleotides in cancer treatment, biosensors for detection, and drug delivery. The 2-day conference took place in February 2024 at the Royan Institute, Tehran. This collaborative effort brought together experts from both basic and clinical research fields. The primary objective of the conference was to address clinical challenges and harness the potential of basic sciences for early cancer diagnosis and treatment, with a robust emphasis on ethical considerations. The conference aimed to ensure optimal patient care while advancing scientific understanding in the field and facilitating effective research collaborations among researchers and enthusiasts dedicated to combating cancer.</p>","PeriodicalId":49224,"journal":{"name":"Cell Journal","volume":"26 5","pages":"329-333"},"PeriodicalIF":1.7,"publicationDate":"2024-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141767774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Streptozotocin Induced Diabetes on One-Carbon Cycle and Sperm Function.","authors":"Farnaz Pouriayevali, Marziyeh Tavalaee, Fatemeh Kazeminasab, Maurizio Dattilo, Mohammad Hossein Nasr-Esfahani","doi":"10.22074/cellj.2024.711928","DOIUrl":"https://doi.org/10.22074/cellj.2024.711928","url":null,"abstract":"<p><p>In this article published in Cell J, Vol 26, No 1, 2024, on pages 81-90, the authors found that the affiliation of authors in address 1 and also the two corresponding authors had accidentally missed during the formatting of the paper. Therefore, we corrected them. The authors would like to apologize for any inconvenience.</p>","PeriodicalId":49224,"journal":{"name":"Cell Journal","volume":"26 4","pages":"276"},"PeriodicalIF":2.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140912942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased Gene Expression of <i>LITAF, TNF-α</i> and <i>BCL6</i> in Endometrial Tissues of Women with Endometriosis: A Case-Control Study.","authors":"Ameneh Saadat Varnosfaderani, Shadi Kalantari, Fariba Ramezanali, Maryam Shahhoseini, Elham Amirchaghmaghi","doi":"10.22074/cellj.2024.2022348.1503","DOIUrl":"10.22074/cellj.2024.2022348.1503","url":null,"abstract":"<p><strong>Objective: </strong>Endometriosis, as a common inflammatory chronic disease is characterized by endometrial tissue growth outside the uterine cavity. It was reported that lipopolysaccharides (LPS) activate a transcription factor called LPSinduced tumor necrosis factor-alpha (LITAF) in macrophages, which induced transcription of cytokine genes such as tumor necrosis factor alpha (<i>TNF-α</i>). B-cell lymphoma 6 protein (BCL6) is a transcription factor which expression was increased in endometrial tissues of infertile women with endometriosis. In addition, it was shown that mRNA and protein of LITAF and BCL6 were inversely related in mature B lymphocytes and B-Cell lymphomas. Accordingly, we investigated gene expression of <i>LITAF, BCL6</i> and ,<i>TNF-α</i> in eutopic and ectopic endometrial tissues of women with endometriosis compared to the controls.</p><p><strong>Materials and methods: </strong>In this case-control study, 10 women with endometriosis (endometriosis group) and 10 women without endometriosis (control group) enrolled after diagnostic laparoscopy. Real-time polymerase chain reaction (PCR) technique was used to quantitatively analyze gene expression. One-Way ANOVA was used for data analysis.</p><p><strong>Results: </strong>This study showed that <i>LITAF</i> gene expression was significantly higher in ectopic endometrial tissues compared to the control samples. Expression level of <i>BCL6</i> gene was significantly increased in the ectopic tissues of women with endometriosis compared to the control and eutopic samples. Although <i>TNF-ɑ</i> gene expression was increased in the ectopic lesions compared to the eutopic and control endometrial samples, these differences were not significant.</p><p><strong>Conclusion: </strong>The results suggested that over-expression of these inflammatory genes in ectopic endometrial lesions can be considered as a molecular scenario in pathophysiology of endometriosis by induction of inflammatory cascades and cellular proliferation.</p>","PeriodicalId":49224,"journal":{"name":"Cell Journal","volume":"26 4","pages":"243-249"},"PeriodicalIF":1.7,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140912951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of miR-20a as A Potential Discerning Biomarker for Non-Invasive versus Invasive Retinoblastoma.","authors":"Ahmad Bereimipour, Saeed Karimi, Mohammad Faranoush, Amir Abbas Hedayati Asl, Monireh Sadat Miri, Leila Satarian, Sara Taleahmad","doi":"10.22074/cellj.2024.2019336.1479","DOIUrl":"https://doi.org/10.22074/cellj.2024.2019336.1479","url":null,"abstract":"<p><strong>Objective: </strong>Intraocular retinoblastoma (RB) is common in kids. Although the cause of this disease is a mutation in the RB1 gene, the formed cancerous mass in different patients is seen in non-invasive states, limited to the ocular cavity or in invasive states distributed to other parts of the body. Because this tumor's aggressiveness cannot be predicted early, these patients receive systemic chemotherapy with multiple drugs. Treating non-invasive and invasive tumors separately reduces chemical drug side effects. The aim of this study was to identify diagnostic biomarkers by separating miRNAs in blood serum from invasive and non-invasive RB patients.</p><p><strong>Materials and methods: </strong>In this experimental study, selected three gene expression omnibus (GEO) datasets. Two were related to serum and tumor tissue miRNAs, and one was related to non-invasive and invasive <i>RB</i> gene expression. Examined <i>RB</i> gene-miRNA relationships. Then, we performed real-time polymerase chain reaction (PCR) on candidate miRNAs in the Y79 cell line and patient blood samples in non-invasive and invasive retinoblastoma.</p><p><strong>Results: </strong>Fourteen high-expression and 7 low-expression miRNAs resulted. <i>MiR-181, miR-135a, miR-20a, miR-373,</i> and <i>miR-191</i> were common genes with differential genes between invasive and non-invasive retinoblastoma. Only <i>MiR-181</i> was upregulated in the Y79 RB cell line. Other candidate miRNAs expressed less. Invasive retinoblastomas increased serum miR-20a and miR-191.</p><p><strong>Conclusion: </strong>Integrated and regular bioinformatics analyses found important miRNAs in patients' and <i>miR-20a, miR- 191</i>, and <i>miR-135a</i> can distinguish non-invasive and invasive retinoblastoma, suggesting further research.</p>","PeriodicalId":49224,"journal":{"name":"Cell Journal","volume":"26 4","pages":"250-258"},"PeriodicalIF":2.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140912944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interference of Bisphenol A on Cumulus Cells Development and Number of Retrieved Mature Oocytes in Unexpected Poor Ovarian Response Women: A Prospective Cohort Study.","authors":"Somayeh Aftabsavad, Zahra Noormohammadi, Ashraf Moini, Morteza Karimipoor","doi":"10.22074/cellj.2024.2020628.1488","DOIUrl":"https://doi.org/10.22074/cellj.2024.2020628.1488","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the relationship between follicular fluid Bisphenol A (BPA) concentrations with alterations in the expressions of <i>NOTCH1-3, CASPASE 3/7, HLA-G,</i> and <i>ICAM-1</i> genes and the number of retrieved mature oocytes (MII oocyte) in the cumulus cells of infertile poor ovarian response stimulates women.</p><p><strong>Materials and methods: </strong>In this prospective cohort study, 80 infertile unexpected poor ovarian response (POR) subjects were selected on the basis of subgroup 1a of the POSEIDON classification. They were divided into two groups: group 1 consisted of 40 women, each with a higher number of metaphase II (MII) oocytes (G1, 3-4 oocytes retrieved), while group 2 comprised of 40 women, each with a lower number of MII oocytes (G2, ≤2 oocytes retrieved). The expressions of the studied genes were evaluated by quantitative-real time polymerase chain reaction (PCR). The concentration of BPA in follicular fluid was measured with HPLC.</p><p><strong>Results: </strong>The expression levels of <i>NOTCH1-3, HLA-G</i>, and <i>ICAM-1</i> genes were significantly lower in G2 than G1 (P<0.05). Meanwhile, <i>CASPASE 3/7</i> expression levels were higher in unexpected POR patients in G2 compared to G1 (P<0.05). There was a significant direct correlation between the levels of <i>NOTCH1-3, HLA-G</i> and <i>ICAM-1</i> gene expressions and there was also a significant inverse correlation (P<0.05) between the levels of CASPASE 3/7, with the number of MII oocytes and embryo development between the two groups. The concentration of BPA in the follicular fluids of G2 was higher compared to G1 (P<0.05).</p><p><strong>Conclusion: </strong>A higher concentration of BPA was associated with a lower number of mature oocytes and oocyte quality in these patients. Also, alterations of <i>NOTCH1-3, CASPASE 3/7, HLA-G,</i> and <i>ICAM-1</i> transcript levels in unexpected POR women were associated with BPA concentration.</p>","PeriodicalId":49224,"journal":{"name":"Cell Journal","volume":"26 4","pages":"267-275"},"PeriodicalIF":2.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140912953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Upregulation of Oxidative Phosphorylation Genes in Cumulus Cells of The Polycystic Ovary Syndrome Patients with or without Insulin Resistance.","authors":"Behnaz Motiee, Seyed Omid Reza Mousavi, Maryam Eslami, Poopak Eftekhari-Yazdi, Fatemeh Hassani, Masood Bazrgar","doi":"10.22074/cellj.2024.2006763.1357","DOIUrl":"https://doi.org/10.22074/cellj.2024.2006763.1357","url":null,"abstract":"<p><strong>Objective: </strong>The relationship between oxidative stress (OS), insulin resistance (IR), and polycystic ovary syndrome (PCOS) is an important medical issue in human reproduction. Some of the oxidative phosphorylation (OXPHOS) genes have been previously studied in granulosa and muscle cells of PCOS patients. Cumulus cells (CCs) remain close to the oocyte even after ovulation. This research has been designed to compare the expression of OXPHOS genes in CCs of PCOS, with or without insulin resistance.</p><p><strong>Materials and methods: </strong>In this experimental study, patients were included in PCOS insulin-resistant, PCOS insulinsensitive (IS), and control (fertile women with male infertility history) groups. The expression of <i>NCF2, TXNIP, UCP2, NDUFB6, ATP5H, COX7C, NDUFA3, SDHA,</i> and <i>SDHB</i> was studied by real-time polymerase chain reaction (PCR), and normalization was performed considering <i>HPRT1</i> and <i>CYC1</i> as reference genes. One-way ANOVA and Tukey test were used for data analysis.</p><p><strong>Results: </strong>The results showed that the expression of <i>NCF2, TXNIP, UCP2,</i> and <i>ATP5H</i> was significantly higher in the IR group than IS and control groups (P<0.01). <i>NDUFB6</i> showed the highest expression in the IS group, which was significantly different from other groups (P<0.01). The other genes of interest, except <i>COX7C</i>, were observed with the most transcriptional levels in the IS group, although there was no significant difference for those genes.</p><p><strong>Conclusion: </strong>Altered expression of genes involved in mitochondrial function compared to the control group in CCs of both IR and IS categories of the PCOS patients suggests that alteration in OXPHOS genes can contribute to the pathophysiology of PCOS.</p>","PeriodicalId":49224,"journal":{"name":"Cell Journal","volume":"26 4","pages":"235-242"},"PeriodicalIF":2.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140912955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Betaine Attenuates The Expression of Vasoactive Mediators and Histological Alterations Associated with Ovarian Hyperstimulation Syndrome in Rats.","authors":"Mohammad Reza Abbasi, Javad Jamshidian, Zahra Basir, Mohammad Reza Tabandeh","doi":"10.22074/cellj.2024.2022353.1504","DOIUrl":"https://doi.org/10.22074/cellj.2024.2022353.1504","url":null,"abstract":"<p><strong>Objective: </strong>Ovarian hyperstimulation syndrome (OHSS) is one female reproductive disorder that can occur after administration of injectable hormonal drugs to stimulate ovulation. Betaine (BET) is an intracellular biomolecule with anti-inflammatory and tissue protective effects. There is no information about its effects in an experimental model of OHSS. The current study aims to investigate the possible effects of BET on abnormal expressions of vasoconstrictor proteins and ovarian histological changes in an experimental OHSS rat model.</p><p><strong>Materials and methods: </strong>In this experimental study, 30 adult female rats (two months old) were randomly divided into six groups (n=5 per group): i. Control, ii. OHSS [10 IU sc equine chorionic gonadotropin (eCG) for 4 days followed by 30 IU sc human chorionic gonadotropin (hCG) on the fifth day], iii. OHSS+BET (200 mg/kg/day, orally for seven days), iv. OHSS+Cabergoline (CAB, 100 mg/kg/day, orally for six days), v. BET, and vi. CAB. Expression levels of vascular endothelial growth factor (VEGF), cyclooxygenase-2 (COX-2), and blood levels of oestradiol (E2) and progesterone (P4) were measured at the end of the experiment. The ovaries were studied for histomorphological changes.</p><p><strong>Results: </strong>Induction of OHSS altered tissue histology, including an increase in the number of corpora lutea and atretic follicles, and decreased the number of follicular reserves. In this group, we observed increased expressions of the VEGF and COX-2 proteins, and increased serum E2 and P4 levels. Administration of CAB and BET significantly attenuated all molecular and histological alterations observed in the OHSS animals.</p><p><strong>Conclusion: </strong>Our findings, for first time, indicate the beneficial effects of BET to reduce OHSS complications in patients by reducing the expressions of vasoactive proteins and improving changes to the ovarian tissues. The findings are similar to CAB and can be a new avenue for future research on BET.</p>","PeriodicalId":49224,"journal":{"name":"Cell Journal","volume":"26 4","pages":"259-266"},"PeriodicalIF":2.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140912941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sperm Parameters and Chromatin Integrity in Men Suffering from Celiac Disease: Insights into Reproductive Health, Case-Control Study.","authors":"Shaghayegh Kiani, Marziyeh Tavalaee, Fatemeh Maghool, Nahid Jamali, Mohammad Hassan Emami, Mohammad Hossein Nasr-Esfahani","doi":"10.22074/cellj.2024.2014048.1432","DOIUrl":"https://doi.org/10.22074/cellj.2024.2014048.1432","url":null,"abstract":"<p><strong>Objective: </strong>Celiac disease is a common chronic inflammatory condition of the small intestine caused by permanent intolerance to gluten/gliadin. It has been demonstrated that oxidative stress is one of the mechanisms that is involved in gliadin toxicity, and there is a correlation between oxidative damage with this disease. Similarly, increased oxidative stress was repeatedly reported in infertile men which led to low-quality of sperm function. Therefore, we aimed to assess sperm parameters and chromatin status in men with Celiac disease.</p><p><strong>Materials and methods: </strong>In this case-control study, semen samples were collected from 11 fertile men without Celiac and 10 men with diagnostic Celiac disease. Basic semen analyses were performed according to the World Health Organization (WHO) 2010 protocol. The percentage of sperm with persistence histones, protamine deficiency, DNA fragmentation, malondialdehyde (MDA), and intracellular reactive oxygen species (ROS) were assessed using aniline blue, chromomycin A3, sperm chromatin structure assay, thiobarbituric acid reactive substances (TBARS) assay, and diacetyldichlorofluorescein staining, respectively.</p><p><strong>Results: </strong>Unlike the sperm parameters, which did not show significant differences between men with Celiac disease and fertile individuals, sperm chromatin maturation (persistence histones and protamine deficiency) and sperm DNA damage in men with Celiac disease were significantly higher compared to fertile individuals (P<0.05). In addition, the percentage of sperm viability in these individuals was significantly lower than that in the fertile individuals (P<0.05). We did not observe any significant differences in sperm lipid peroxidation and intracellular ROS levels between the two study groups (P>0.05).</p><p><strong>Conclusion: </strong>Celiac disease affects sperm chromatin maturation and DNA fragmentation, emphasizing its impact on reproductive health.</p>","PeriodicalId":49224,"journal":{"name":"Cell Journal","volume":"26 3","pages":"202-208"},"PeriodicalIF":2.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140853357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>In Vivo</i> Vascularization of Endothelial Cells Derived from Bone Marrow Mesenchymal Stem Cells in SCID Mouse Model.","authors":"Abdolamir Allameh, Maryam Jazayeri, Maryam Adelipour","doi":"10.22074/cellj.2024.711902","DOIUrl":"https://doi.org/10.22074/cellj.2024.711902","url":null,"abstract":"<p><p>In this article published in Cell J, Vol 18, No 2, Jul-Sep (Summer) 2016, on pages 179-188, the authors found that Figure 2A was the same as the one that has already been published and it was confusing. The following figure's legend is corrected in reference 9. The authors would like to apologies for any inconvenience caused.</p>","PeriodicalId":49224,"journal":{"name":"Cell Journal","volume":"26 3","pages":"212"},"PeriodicalIF":2.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140856718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}