Endocrine最新文献

{"title":"Adrenal lesions in patients with abdominal multitrauma.","authors":"Anna Kistner, Lisa Kekonius, Jan Calissendorff, Seppo Koskinen, Henrik Falhammar","doi":"10.1007/s12020-025-04321-9","DOIUrl":"10.1007/s12020-025-04321-9","url":null,"abstract":"<p><strong>Purpose: </strong>Most adrenal lesions are less than 2 cm and can easily be ignored during primary review of computed tomography (CT)-scans with another question. Furthermore, adrenal lesions, including adrenal hematomas, can easily be missed in patients with multitrauma. We aimed to determine the incidence of adrenal lesions in patients with multitrauma.</p><p><strong>Methods: </strong>This retrospective, single-center cohort analysis included 1373 patients with multitrauma (71.2% males) with a mean age of 42 (95%CI 41-43) years. One radiologist re-examined all multitrauma CT performed 2013-2017 using thin sliced imaging in at least two depictions. A second radiologist re-examined patients where an abnormality was found. Adrenal abnormalities were labelled adrenal lesions (size ≥10 mm) or hematomas, respectively. Clinical data were collected.</p><p><strong>Results: </strong>The adrenal lesion prevalence was 2.7% (37/1373, 78% males, 22% bilateral). Of these 27% (10/37) were mentioned in the radiological report, and in those with a size ≥15 mm (n = 13), 38% (5/13) were mentioned. Of the unilateral adrenal lesions 86% (25/29) were left-sided. In the adrenal lesion group during the mean follow-up time of 75 (61-90) months none had surgery, 6% had hormones measured (all normal), and 7% had repeated adrenal imaging. The adrenal hematoma prevalence was 5.0% (68/1373, 10% bilateral). No patient had both an adrenal hematoma and an adrenal lesion. Of the unilateral hematomas 42% (26/62) were not mentioned. Of the hematomas 77% were right-sided. No patient with adrenal abnormalities had signs of adrenal insufficiency. 30-day survival rates in the adrenal lesion and hematomas groups were similar, but the hematoma group had higher injury severity score, but no longer length of hospital stay.</p><p><strong>Conclusions: </strong>The prevalence of adrenal tumors was 2.7% and adrenal hematomas 5.0%. Most lesions were not mentioned in the image report. Few had hormonal evaluation or adrenal imaging follow-up. Survival rates were similar between the two groups.</p>","PeriodicalId":49211,"journal":{"name":"Endocrine","volume":" ","pages":"321-328"},"PeriodicalIF":2.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144340546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipocalin-2 levels in children with idiopathic short stature.","authors":"Naama Fisch-Shvalb, Meytal Bar-Maisels, Michal Yackobovitch-Gavan, Moshe Phillip, Galia Gat-Yablonski","doi":"10.1007/s12020-025-04437-y","DOIUrl":"https://doi.org/10.1007/s12020-025-04437-y","url":null,"abstract":"","PeriodicalId":49211,"journal":{"name":"Endocrine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145179783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Adrenal lesions in patients with abdominal multitrauma\".","authors":"Leela Lakshmi Sai Srinivas Parasa, Bhaskar Kambhampati, Ranjana Sah","doi":"10.1007/s12020-025-04440-3","DOIUrl":"https://doi.org/10.1007/s12020-025-04440-3","url":null,"abstract":"","PeriodicalId":49211,"journal":{"name":"Endocrine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145179809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical pathway management of diabetic Charcot neuro-osteoarthropathy.","authors":"Liyi Li, Haitao Zhang, Jinan Chen, Guangyuan Xiang, Yuedong Chen, Aiping Wang","doi":"10.1007/s12020-025-04438-x","DOIUrl":"https://doi.org/10.1007/s12020-025-04438-x","url":null,"abstract":"","PeriodicalId":49211,"journal":{"name":"Endocrine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145179791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical characteristics and survival of patients with calcitonin-secreting neuroendocrine neoplasms: experience from a series of 71 patients.","authors":"Bojana Popovic, Valentina Elezovic Kovacevic, Dusan Ilic, Milica Opalic Palibrk, Lena Radic, Katarina Krstic, Marjan Micev, Nemanja Menković, Ana Petkovic, Vera Artiko, Branislava Radovic, Jelena Petrovic, Vladimir Dugalic, Nikica Grubor, Maja Ercegovac, Milan Savic, Sanja Ognjanovic","doi":"10.1007/s12020-025-04439-w","DOIUrl":"https://doi.org/10.1007/s12020-025-04439-w","url":null,"abstract":"","PeriodicalId":49211,"journal":{"name":"Endocrine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145179869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical features and literature review in children and adolescent patients with functioning gonadotroph pituitary neuroendocrine tumors.","authors":"Yingying Chen, Linjie Wang, Yong Yao, Kan Deng, Xinxin Mao, Ou Wang, Huijuan Zhu, Lian Duan","doi":"10.1007/s12020-025-04436-z","DOIUrl":"https://doi.org/10.1007/s12020-025-04436-z","url":null,"abstract":"","PeriodicalId":49211,"journal":{"name":"Endocrine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between dietary patterns and cardiovascular mortality in patients with metabolic dysfunction-associated steatotic liver disease.","authors":"Yu-Jin Kwon, Hye Sun Lee, Ji-Won Lee","doi":"10.1007/s12020-025-04365-x","DOIUrl":"https://doi.org/10.1007/s12020-025-04365-x","url":null,"abstract":"<p><strong>Purpose: </strong>Given the heightened cardiovascular risk in patients with metabolic dysfunction-associated steatotic liver disease (MASLD), identifying dietary patterns associated with reduced cardiovascular risk is essential. This study aimed to investigate the association between adherence to various dietary patterns and cardiovascular disease (CVD) mortality in a middle-aged Korean MASLD population.</p><p><strong>Methods: </strong>Baseline data from 32,091 adults aged 40 years and older enrolled in the Korean Genome and Epidemiology Study (KoGES) between 2004 and 2013 were analyzed. Dietary intake was assessed using a validated semi-quantitative food frequency questionnaire, and principal component analysis was applied to identify distinct dietary patterns. The primary outcome was CVD mortality, assessed using Cox proportional hazards models adjusted for confounders, including age, sex, body mass index, smoking status, alcohol intake, physical activity, total calorie intake, hypertension, diabetes, and dyslipidemia.</p><p><strong>Results: </strong>Adherence to the Korean Mediterranean-style diet was associated with a significantly reduced risk of CVD mortality in MASLD patients, with those in the highest Korean Mediterranean-style diet pattern quartile having a 33% lower risk than those in the lowest quartile (hazards ratio: 0.67, 95% confidence interval: 0.45-1.00, p = 0.048). Other dietary patterns, including the processed food and dairy diet, animal protein-rich diet, grain-based diet, as well as refined carbohydrate and fat-rich diet, were not significantly associated with CVD mortality.</p><p><strong>Conclusions: </strong>Adherence to Korean Mediterranean-style diet pattern was associated with a lower risk of CVD mortality in Korean adults with MASLD, highlighting its potential as an effective dietary strategy for managing cardiovascular risk in MASLD patients, even in non-Western populations.</p>","PeriodicalId":49211,"journal":{"name":"Endocrine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bulk and Single-cell transcriptomic profiling identifies C1QA as an Immune-Associated hub genes in graves' ophthalmopathy.","authors":"Lin-Na Li, Zong-Ji Zheng, Jie-Man Wu, Shu-Xian Li, Meng-Yi Cai, Meng-Chen Zou","doi":"10.1007/s12020-025-04426-1","DOIUrl":"https://doi.org/10.1007/s12020-025-04426-1","url":null,"abstract":"","PeriodicalId":49211,"journal":{"name":"Endocrine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of Age-Specific algorithms for diabetes prediction.","authors":"Shigehiro Karashima, Haruka Nishida, Yu Ishikawa, Ren Mizoguchi, Atsushi Hashimoto, Toshitaka Sawamura, Akihiro Nomura, Hayato Tada, Kenji Furukawa, Akitaka Higashi, Hiroyuki Mori, Kohei Hirako, Yuma Morisaki, Makoto Fujiu, Hidetaka Nambo","doi":"10.1007/s12020-025-04428-z","DOIUrl":"https://doi.org/10.1007/s12020-025-04428-z","url":null,"abstract":"","PeriodicalId":49211,"journal":{"name":"Endocrine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic screening in a large Chinese cohort of adult-onset non-surgical hypoparathyroidism.","authors":"Jing Yang, Yue Jiang, Bingwei Zhang, An Song, Yi Yang, Jiajia Wang, Yan Jiang, Mei Li, Weibo Xia, Youjun Wang, Xiaoping Xing, Min Nie, Ou Wang","doi":"10.1007/s12020-025-04420-7","DOIUrl":"https://doi.org/10.1007/s12020-025-04420-7","url":null,"abstract":"","PeriodicalId":49211,"journal":{"name":"Endocrine","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}