Indian Journal of Otolaryngology and Head and Neck Surgery最新文献

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Exploring Benign Vocal Cord Polyp Treatment: A Holistic Analysis of Plasma Ablation and Laser Excision Phonosurgery Practices Incorporating Subjective, Objective, and Videostroboscopic Assessments. 探讨良性声带息肉的治疗:等离子消融和激光切除声外科实践的整体分析,包括主观、客观和频闪评估。
IF 0.4
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-12 DOI: 10.1007/s12070-025-05632-z
Sajith Abraham, Karthika Chettuvatti, Ramandeep Singh Virk
{"title":"Exploring Benign Vocal Cord Polyp Treatment: A Holistic Analysis of Plasma Ablation and Laser Excision Phonosurgery Practices Incorporating Subjective, Objective, and Videostroboscopic Assessments.","authors":"Sajith Abraham, Karthika Chettuvatti, Ramandeep Singh Virk","doi":"10.1007/s12070-025-05632-z","DOIUrl":"10.1007/s12070-025-05632-z","url":null,"abstract":"<p><p>Surgical techniques for benign vocal cord lesions, such as vocal cord polyps, have witnessed rapid technological advancements. It is imperative for developing nations like India to keep pace with this evolving technology. Our study compares two recently introduced modalities of vocal cord polyp treatment, assessing both subjective and objective outcomes. A randomized controlled trial was conducted at a tertiary care centre in Northern India, enrolling 20 patients in the laser excision group and another 20 in the plasma ablation group for the treatment of benign vocal cord polyps. The study involved detailed subjective assessments using the GRBAS scale and VHI tools, along with objective measurements using Maximum Phonation Time (MPT). Additionally, Videostroboscopy was also performed for all patients both before and after the surgical procedure. Thorough assessment of the GRBAS score and VHI revealed substantial improvement postoperatively (<i>p</i> < 0.0001) in vocal cord polyp patients undergoing both laser and plasma ablation. Notably, laser ablation demonstrated superior subjective improvement compared to plasma. (<i>p</i> < 0.0001). Furthermore, aerodynamic evaluations, such as MPT, exhibited enhancement in both subgroups following the procedure. Videostroboscopic findings indicated comparable improvements in both subgroups. Our study concluded that both microlaryngeal plasma ablation and laser excision are effective surgical modalities for managing vocal cord polyps. Both procedures led to improvements in subjective and objective outcomes, with patients expressing higher satisfaction levels with laser excision.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12070-025-05632-z.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3049-3055"},"PeriodicalIF":0.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
To Determine the Efficacy of Balloon Sinuplasty over Conventional Functional Endoscopic Sinus Surgery. 目的:探讨球囊鼻窦成形术相对于传统功能性鼻窦内窥镜手术的疗效。
IF 0.4
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-26 DOI: 10.1007/s12070-025-05634-x
V Suresh, M Gowrishankar, V Prithiv, Bhanupriya Jain
{"title":"To Determine the Efficacy of Balloon Sinuplasty over Conventional Functional Endoscopic Sinus Surgery.","authors":"V Suresh, M Gowrishankar, V Prithiv, Bhanupriya Jain","doi":"10.1007/s12070-025-05634-x","DOIUrl":"10.1007/s12070-025-05634-x","url":null,"abstract":"<p><p>Balloon sinuplasty is an innovative, minimally invasive technique for chronic rhinosinusitis in the field of endoscopic rhinology. Balloon sinuplasty has a good outcome and is an effective tool in the treatment of various sinus pathologies. The aim of the study is to assess the efficacy of balloon sinuplasty in chronic rhinosinusitis patients compared to Conventional Functional Endoscopic Sinus Surgery (FESS) with limited diseases based on our own experience. In our prospective comparative study, we included 75 patients with chronic maxillary sinusitis who did not respond to medical therapy. The selected 75 patients were randomly divided into two groups regardless of age and sex, labeled as Group A and Group B. The Group A patients underwent balloon sinuplasty and were compared with Group B patients who underwent Conventional FESS with the same surgery team. The study compared the outcomes of Balloon Sinuplasty and Conventional FESS. Results showed no significant difference in Lund Mackay scores or SNOT-22 scores between the two procedures. Balloon Sinuplasty took less time and showed less blood loss during surgery compared to Conventional FESS. Balloon Sinuplasty also showed better post-operative ostium status, fewer synechiae, and improved post-operative symptom scores. Balloon sinuplasty is a minimally invasive sinus surgery in rhinology compared to Conventional FESS. Despite its limitations, it is considered an effective method for opening blocked sinus ostia and restoring sinus drainage.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3065-3070"},"PeriodicalIF":0.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transverse Cervical Nerve Schwannoma: A Rare Case Report of Anterior Neck Swelling. 颈横神经鞘瘤:颈前肿胀的罕见病例报告。
IF 0.4
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-05-31 DOI: 10.1007/s12070-025-05464-x
Prince Handa, Anjan K Sahoo, V Dhanoush Kumar, V Megha Chandran
{"title":"Transverse Cervical Nerve Schwannoma: A Rare Case Report of Anterior Neck Swelling.","authors":"Prince Handa, Anjan K Sahoo, V Dhanoush Kumar, V Megha Chandran","doi":"10.1007/s12070-025-05464-x","DOIUrl":"10.1007/s12070-025-05464-x","url":null,"abstract":"<p><p>Schwannomas arising from the transverse cervical nerve is a rare entity, with no documented cases in the literature. These tumours pose diagnostic challenges requiring detailed clinicoradiological evaluation and histopathological confirmation. We present a successfully resected schwannoma of transverse cervical nerve schwannoma in a 44-year-old female.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3099-3102"},"PeriodicalIF":0.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Profiling Expression of BRAC2 Gene in Cases of Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders-A Retrospective Study. bracc2基因在口腔鳞状细胞癌和口腔潜在恶性疾病中的表达——一项回顾性研究
IF 0.4
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-05-24 DOI: 10.1007/s12070-025-05541-1
Arushi Tomar, Hrithik Kaushal Jain
{"title":"Profiling Expression of BRAC2 Gene in Cases of Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders-A Retrospective Study.","authors":"Arushi Tomar, Hrithik Kaushal Jain","doi":"10.1007/s12070-025-05541-1","DOIUrl":"10.1007/s12070-025-05541-1","url":null,"abstract":"<p><p>Oral potentially malignant disorders (OPMD) are heterogeneous mucosal lesions of the oral cavity that have a higher chance of developing into malignancy, such as oral squamous cell carcinoma (OSCC), in contrast to their normal and other diseased counterparts. Information on diagnosed cases of OSCC and OPMDs at different grading stages was stored in the department's archives. The diagnosis was assessed and confirmed by two oral pathologists. They were sent for immunohistochemical examination after receiving their individual formalin-fixed, paraffin-embedded (FFPE) samples from the Department's archives. Accordingly, this study discovered that the BRCA2 gene, also known as the tumour suppression gene (TSG), was expressed in cases of OSCC and OPMDs. The results showed that when grade or severity increased, neither group's expression of this gene changed. We therefore conclude that a large number of studies with sample sizes would be necessary to confirm the findings, as well as to employ new tissue samples to confirm the expression of the BRCA2 gene and to incorporate methods like qPCR and Western blot (WB).</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"2784-2789"},"PeriodicalIF":0.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297127/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Solitary Fibrous Tumor of the Oral Cavity: A Rare Entity with Immunohistochemical Profiling. 口腔孤立性纤维性肿瘤:一种具有免疫组织化学特征的罕见肿瘤。
IF 0.4
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-02 DOI: 10.1007/s12070-025-05642-x
S Aravindan, Nikita Kashyap, Tathagata Bhattacharjee, S Srihari, Jay Gopal Ray
{"title":"Solitary Fibrous Tumor of the Oral Cavity: A Rare Entity with Immunohistochemical Profiling.","authors":"S Aravindan, Nikita Kashyap, Tathagata Bhattacharjee, S Srihari, Jay Gopal Ray","doi":"10.1007/s12070-025-05642-x","DOIUrl":"10.1007/s12070-025-05642-x","url":null,"abstract":"<p><p>Solitary fibrous tumor (SFT) is a rare mesenchymal tissue neoplasm that can occur at all anatomic sites, commonly at the pleura. This uncommon mesenchymal tumor can arise in various soft tissues and organs throughout the body, primarily affecting adults and rarely seen in children. In the head & neck region, frequent sites involved are oral cavity, sinonasal tract and orbit. Histopathologically, these tumors are characterized by uniform, spindle-shaped to ovoid fibroblastic cells and a distinctive staghorn vascular pattern. Immunohistochemical analysis reveals that the tumor cells are consistently positive for CD34 and STAT6 in nearly all cases. In this article, we present a rare case of a solitary fibrous tumor located in the mandibular lingual gingiva of a 35-year-old female, with supporting immunohistochemical evidence.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3239-3242"},"PeriodicalIF":0.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Mortality and Risk Analysis in Mucormycosis Cases: Pre-Pandemic Versus COVID-19 Association. 毛霉病病例的死亡率和风险比较分析:大流行前与COVID-19的相关性
IF 0.4
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-03 DOI: 10.1007/s12070-025-05631-0
Masoud Janipour, Alireza Shahriari, Ali Faramarzi, Seyed Hossein Owji, Mohammad Ehsan Golshannia, Maryam Kherad, Maryam Rahimi, Vahid Hajianpour, Behzad Khademi, Amirhossein Babaei
{"title":"Comparative Mortality and Risk Analysis in Mucormycosis Cases: Pre-Pandemic Versus COVID-19 Association.","authors":"Masoud Janipour, Alireza Shahriari, Ali Faramarzi, Seyed Hossein Owji, Mohammad Ehsan Golshannia, Maryam Kherad, Maryam Rahimi, Vahid Hajianpour, Behzad Khademi, Amirhossein Babaei","doi":"10.1007/s12070-025-05631-0","DOIUrl":"10.1007/s12070-025-05631-0","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to compare the clinical profiles, outcomes, and mortality-related risk factors of COVID-19-associated mucormycosis (CAM) with cases identified before the pandemic. Additionally, it seeks to evaluate the impact of the COVID-19 pandemic on the epidemiology and severity of mucormycosis infections.</p><p><strong>Study design: </strong>Retrospective, observational study.</p><p><strong>Setting: </strong>The study was conducted across multiple medical centers in Shiraz, Iran.</p><p><strong>Methods: </strong>We reviewed clinical data of patients diagnosed with mucormycosis before and during the COVID-19 pandemic. The study included a detailed analysis of demographic profiles, clinical characteristics, risk factors, treatment outcomes, and mortality. Mortality-related risk factors were specifically analyzed through logistic regression models to identify predictors of poor outcomes in CAM patients.</p><p><strong>Results: </strong>The study included 122 cases of mucormycosis, with 85 cases associated with COVID-19. Patients with CAM showed higher prevalences of diabetes mellitus and hypertension compared to pre-pandemic cases, while malignancies were higher in peri-pandemic cases than in CAM cases (<i>p</i> < 0.05). CAM cases also demonstrated significantly higher in-hospital mortality (23.1%) compared to pre-pandemic cases (7.7%). Elevated platelet counts and the presence of periorbital edema were more commonly observed in CAM patients. Mortality-based analysis indicated that malignancies and high platelet counts were significant predictors of mortality in CAM patients.</p><p><strong>Conclusion: </strong>COVID-19 has markedly affected the severity and mortality of mucormycosis, with CAM cases showing worse outcomes than pre-pandemic incidences. Our study emphasizes the need for aggressive management and increased awareness of risk factors to enhance survival rates in CAM patients during the pandemic.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3040-3048"},"PeriodicalIF":0.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intradermal Nevus in the External Auditory Canal- A Case Report and Literature Review. 外耳道皮内痣1例并文献复习。
IF 0.4
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-05-29 DOI: 10.1007/s12070-025-05603-4
Deviprasad Dosemane, Meera Niranjan Khadilkar, Hema Kini, Pooja Varshini Raja, Saraswathi Ram Mohan, Kiran Hegde
{"title":"Intradermal Nevus in the External Auditory Canal- A Case Report and Literature Review.","authors":"Deviprasad Dosemane, Meera Niranjan Khadilkar, Hema Kini, Pooja Varshini Raja, Saraswathi Ram Mohan, Kiran Hegde","doi":"10.1007/s12070-025-05603-4","DOIUrl":"10.1007/s12070-025-05603-4","url":null,"abstract":"<p><p>Melanocytic nevus (MN) is a common skin lesion; however, its presence in the external auditory canal (EAC) is uncommon. Following previous reports on various treatment approaches, we share our experience with endoscopic resection in managing a case of MN in EAC. A 44-year-old woman presented with prolonged ear blockage with intermittent whitish ear discharge for the past year. Single-handed endoscopic resection is effective in treating a rare external auditory canal melanocytic nevus. This report also illustrates the benefits of endoscopy in early diagnosis and management.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3177-3182"},"PeriodicalIF":0.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lateral Periodontal Cyst in a 10-year-old Child. 10岁儿童外侧牙周囊肿1例。
IF 0.4
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-05-28 DOI: 10.1007/s12070-025-05589-z
Paolo Boffano, Muhammad Ruslin
{"title":"Lateral Periodontal Cyst in a 10-year-old Child.","authors":"Paolo Boffano, Muhammad Ruslin","doi":"10.1007/s12070-025-05589-z","DOIUrl":"10.1007/s12070-025-05589-z","url":null,"abstract":"<p><p>The lateral periodontal cyst (LPC) is a relatively rare odontogenic non-inflammatory cyst that arises in the alveolar process in close proximity to the roots of vital teeth. LPC is considered to be an odontogenic cyst of developmental origin that arise in close proximity to the periodontal space of teeth, with the exclusion of an inflammatory pathogenesis. LPC is most frequently observed in the premolar region of the mandible, followed by the maxillary incisor region. It is preferentially diagnosed in individuals aged between 40 and 70 years, although it may be occasionally diagnosed in patients outside this age range. LPC is usually asymptomatic and it is usually found by a combination of a clinical finding of a gingival swelling in the facial or lingual aspect of a tooth and of a radiographic finding. The involved teeth are usually vital. The radiographic feature of LPC is a well circumscribed ovoid-round radiolucent area, usually with a less than 1 cm diameter. The aim of the present article is to present an unusual case of LPC in the molar region in a 10-year-old child, and to discuss its diagnosis and management.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3147-3150"},"PeriodicalIF":0.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating the Labyrinth: A Rare Encounter with an Exceptionally Long Facial Nerve Trunk in Total Parotidectomy: A Case Report. 导航迷宫:在腮腺全切除术中罕见遇到异常长的面神经干:1例报告。
IF 0.4
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-05-31 DOI: 10.1007/s12070-025-05590-6
Narayanan Rajavelu, Arun Parambath
{"title":"Navigating the Labyrinth: A Rare Encounter with an Exceptionally Long Facial Nerve Trunk in Total Parotidectomy: A Case Report.","authors":"Narayanan Rajavelu, Arun Parambath","doi":"10.1007/s12070-025-05590-6","DOIUrl":"10.1007/s12070-025-05590-6","url":null,"abstract":"<p><p>Total parotidectomy poses significant challenges due to the dissection and preservation of the facial nerve. The branching pattern of the facial nerve varies, making identification of the facial nerve trunk a crucial step in surgery. The average length of the facial nerve trunk is 14.1 mm. This case highlights the encounter with an unusually long facial nerve trunk during parotidectomy and its management.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3151-3153"},"PeriodicalIF":0.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Factors Predicting Recurrence in Oral Squamous Cell Carcinoma. 口腔鳞状细胞癌复发预测因素的评价。
IF 0.4
Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-12 DOI: 10.1007/s12070-025-05637-8
Ridhi Gupta, Vipin Arora, Pragya Shukla, Sonal Sharma
{"title":"Evaluation of Factors Predicting Recurrence in Oral Squamous Cell Carcinoma.","authors":"Ridhi Gupta, Vipin Arora, Pragya Shukla, Sonal Sharma","doi":"10.1007/s12070-025-05637-8","DOIUrl":"10.1007/s12070-025-05637-8","url":null,"abstract":"<p><p>Oral cancer is the most common type of cancer in Indian males. Recurrent disease occurs in 17-40% of patients after primary treatment. Out of these around 20-30% recur at primary site and 10-15% at loco-regional nodal area with greater than 90% of recurrences occurring in first 2 years Survival rate is less even after advancement in management strategies. Most of the patients present at an advanced stage of the disease when the lymph node metastasis has already occurred which determines the outcome and leads to poor prognosis. Even if meticulous treatment, the risk of regional recurrence cannot be eliminated. We undertook to study and compare the factors responsible for locoregional control rate, distant control rate, disease free survival rate, recurrence free survival time and overall survival time. All patients enrolled in Department of Otorhinolaryngology, GTBH and DSCI, Delhi with surgery as integral part of treatment and upto 2 year of follow up were included and studied. Bony invasion (<i>p</i> = 0.001) and positive margins (<i>p</i> = 0.006) were found to be significant predictor of recurrence. LVI and Lymph node staging decreased RFS time (<i>p</i> < 0.05). LVI and ECE was associated decreased OS. 2 year overall survival rate with and without recurrence were 36% and 68% respectively. Mortality rates after recurrence was found to be 62%, RFS was 51%. Histopathologically, advanced diseases are associated with high recurrence rate, Bone involvement, margin status, LVI, ECE, advanced N-Stage being important predictors. Recurrence is always associated with poor outcome.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"77 8","pages":"3084-3090"},"PeriodicalIF":0.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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