Solitary Fibrous Tumor of the Oral Cavity: A Rare Entity with Immunohistochemical Profiling.

IF 0.4 Q4 SURGERY
S Aravindan, Nikita Kashyap, Tathagata Bhattacharjee, S Srihari, Jay Gopal Ray
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引用次数: 0

Abstract

Solitary fibrous tumor (SFT) is a rare mesenchymal tissue neoplasm that can occur at all anatomic sites, commonly at the pleura. This uncommon mesenchymal tumor can arise in various soft tissues and organs throughout the body, primarily affecting adults and rarely seen in children. In the head & neck region, frequent sites involved are oral cavity, sinonasal tract and orbit. Histopathologically, these tumors are characterized by uniform, spindle-shaped to ovoid fibroblastic cells and a distinctive staghorn vascular pattern. Immunohistochemical analysis reveals that the tumor cells are consistently positive for CD34 and STAT6 in nearly all cases. In this article, we present a rare case of a solitary fibrous tumor located in the mandibular lingual gingiva of a 35-year-old female, with supporting immunohistochemical evidence.

口腔孤立性纤维性肿瘤:一种具有免疫组织化学特征的罕见肿瘤。
孤立性纤维性肿瘤(SFT)是一种罕见的间质组织肿瘤,可发生在所有解剖部位,常见于胸膜。这种不常见的间充质肿瘤可发生在全身的各种软组织和器官中,主要影响成人,很少见于儿童。在头颈部,常见的受累部位是口腔、鼻道和眼眶。组织病理学上,这些肿瘤的特征是均匀的纺锤形到卵形的成纤维细胞和独特的鹿角血管模式。免疫组化分析显示,几乎所有病例的肿瘤细胞都一致呈CD34和STAT6阳性。在这篇文章中,我们报告了一个罕见的病例,一个孤立的纤维性肿瘤位于一个35岁的女性下颌骨舌龈,并支持免疫组织化学证据。
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
226
审稿时长
6-12 weeks
期刊介绍: Indian Journal of Otolaryngology and Head & Neck Surgery was founded as Indian Journal of Otolaryngology in 1949 as a scientific Journal published by the Association of Otolaryngologists of India and was later rechristened as IJOHNS to incorporate the changes and progress. IJOHNS, undoubtedly one of the oldest Journals in India, is the official publication of the Association of Otolaryngologists of India and is about to publish it is 67th Volume in 2015. The Journal published quarterly accepts articles in general Oto-Rhino-Laryngology and various subspecialities such as Otology, Rhinology, Laryngology and Phonosurgery, Neurotology, Head and Neck Surgery etc. The Journal acts as a window to showcase and project the clinical and research work done by Otolaryngologists community in India and around the world. It is a continued source of useful clinical information with peer review by eminent Otolaryngologists of repute in their respective fields. The Journal accepts articles pertaining to clinical reports, Clinical studies, Research articles in basic and applied Otolaryngology, short Communications, Clinical records reporting unusual presentations or lesions and new surgical techniques. The journal acts as a catalyst and mirrors the Indian Otolaryngologist’s active interests and pursuits. The Journal also invites articles from senior and experienced authors on interesting topics in Otolaryngology and allied sciences from all over the world. The print version is distributed free to about 4000 members of Association of Otolaryngologists of India and the e-Journal shortly going to make its appearance on the Springer Board can be accessed by all the members. Association of Otolaryngologists of India and M/s Springer India group have come together to co-publish IJOHNS from January 2007 and this bondage is going to provide an impetus to the Journal in terms of international presence and global exposure.
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