Iranian Journal of Public Health最新文献

{"title":"The Relationship between Sleep and Competitive Anxiety in Paralympic Medalists.","authors":"Sang-Hyuk Park, Seung-Taek Lim","doi":"10.18502/ijph.v53i10.16725","DOIUrl":"10.18502/ijph.v53i10.16725","url":null,"abstract":"","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 10","pages":"2380-2381"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Reporting Quality of Systematic Reviews on Health Economic Evaluation Studies Based on the CHEERS Statement: An Overview of Reviews.","authors":"Fakhraddin Daastari, Maryam Tajvar, Amin Mohammadi, Badriyeh Karami","doi":"10.18502/ijph.v53i10.16699","DOIUrl":"10.18502/ijph.v53i10.16699","url":null,"abstract":"<p><strong>Background: </strong>Economic evaluations in healthcare are designed to inform decisions by the estimation of cost and effect trade-off of two or more interventions. We aimed to evaluate the standards of systematic reviews on health economic evaluation studies using the CHEERS (Consolidated Health Economic Evaluation Report Standards) tool.</p><p><strong>Methods: </strong>We searched the PubMed database with keywords CHEERS and its complete form in combination with keywords related to cost or economic evaluation without language and time limits until November 17, 2021. The CHEERS tool was then used to include systematic reviews.</p><p><strong>Results: </strong>Overall, 32 systematic reviews, included 610 primary studies were included. Of the 32 included studies, only 1 study (3.1%) had poor quality, 5 studies (15.6%) had good quality, remaining studies had very good and excellent quality.</p><p><strong>Conclusion: </strong>Some studies still have problems in expressing the standards. The necessity of standards for reporting economic evaluation studies in the field of health is very serious, and Cheers is one of the most important tools.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 10","pages":"2214-2225"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Mortality Statistics in Turkey from 2017 to 2022: An Analysis of the Impact of COVID-19.","authors":"Cemil Çelik, Uğur Ata, Naile Esra Saka","doi":"10.18502/ijph.v53i10.16719","DOIUrl":"10.18502/ijph.v53i10.16719","url":null,"abstract":"<p><strong>Background: </strong>Examining death statistics at regular intervals is highly useful for assessing public health. This study aimed to analyze cause-specific mortality statistics, to ascertain their distribution over the years, and to offer remedial solutions to enhance public health outcomes.</p><p><strong>Methods: </strong>In this retrospective descriptive study, an analysis was conducted on data sourced from the \"Death and Cause of Death Statistics\" provided by the Turkish Statistical Institute between 2017 and 2022.</p><p><strong>Results: </strong>While the crude mortality rate remained stable from 2017 to 2019, a discernible increase in mortality rates has been observed since 2020, attributed to the impact of the pandemic. The crude death rate was the highest in the <5 yr and ≥65 yr age groups. Approximately 70% of the total mortality cases in Turkey were attributed to cardiovascular diseases, cancers, respiratory diseases, and diabetes.</p><p><strong>Conclusion: </strong>Given the world's rapidly aging population, an increase in deaths related to the four major noncommunicable diseases is foreseen. Therefore, there is an imperative need to enhance efforts aimed at preventing and controlling these diseases.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 10","pages":"2318-2327"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systemic Sarcoidosis Revealed by Sarcoidal Granulomatous Reaction after Tattooing.","authors":"Masoumeh Roohaninasab, Safoura Shakoei, Azadeh Goodarzi, Parvin Mansouri, Farahnaz Nikkhah","doi":"10.18502/ijph.v53i10.16726","DOIUrl":"10.18502/ijph.v53i10.16726","url":null,"abstract":"","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 10","pages":"2382-2384"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>MiR-21-5p</i> Promotes Osteogenic Differentiation and Calcification of Valvular Interstitial Cells by Targeting <i>TGFBI</i> in Calcific Aortic Valve Disease.","authors":"Yan Gu, Rongjin Chen, Jianxiang Song, Zhan Shi, Jixiang Wu, Huiwen Chang, Conghu Yuan, Woda Shi, Yajun Zhang","doi":"10.18502/ijph.v53i10.16703","DOIUrl":"10.18502/ijph.v53i10.16703","url":null,"abstract":"<p><strong>Background: </strong>Calcific aortic valve disease (CAVD) is the most common heart relating disease with high morbidity and mortality, especially in elderly population. While extensive investigations have been devoted to the study of mechanistic pathways related to CAVD, the key factors and mechanisms mediating valve mineralization remain unclear. The aim of this study is to investigate the role of mirnas and their downstream targets in CAVD disease progression. A previous recent multi-omics study suggested a novel CAVD molecular interaction network contained <i>miR-21-5p</i>.</p><p><strong>Methods: </strong>CAV and their pair-matched adjacent normal tissues were obtained from 15 patients pathologically diagnosed as CAVD and admitted in Yancheng Third People's Hospital (The Sixth Affiliated Hospital of Nantong University) from 2019-2021. RT-qPCR was utilized for detection of <i>miR-21-5p</i> and related protein expression levels to confirm the related factors in CAVD progression. Western blotting was applied to strengthen the results of RT-qPCR and confirm osteogenic differentiation of VICs via biomarker detection. The staining of alkaline phosphatase (ALP) and alizarin red was performed to assess the degree of VIC mineralization.</p><p><strong>Results: </strong>We found that <i>miR-21-5p</i> was remarkably increased (<i>P</i><0.0001) in calcified aortic valves (AVs) whereas <i>TGFBI</i> was diminished (<i>P</i><0.01) in CAVD samples compared to the paired normal tissues from CAVD patients. Additionally, <i>TGFBI</i> was targeted by <i>miR-21-5p</i>. Furthermore, overexpressing <i>TGFBI</i> could block VIC osteogenic differentiation mediated by <i>miR-21-5p</i>. To sum up, <i>miR-21-5p</i> promotes VIC osteogenic differentiation and calcification via <i>TGFBI</i> in CAVD progression.</p><p><strong>Conclusion: </strong>Our work might bring a sight on underlying mechanisms of CAVD progression and provide a possible therapeutic target for diagnosis and treatment.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 10","pages":"2260-2270"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic and Health Characteristics as Predictors of Social Support in Elderly People with Visual Impairment: Evidence from Serbia.","authors":"Natalija Djurovic, Snezana Radovanovic, Olgica Mihaljevic, Jovana Radovanovic, Milos Stepovic, Marija Kovacevic, Katarina Janicijevic, Gordana Djordjevic, Ognjen Djordjevic, Gordana Gajovic, Nela Djonovic, Tamara Dimovic, Nikoleta Janicijevic, Milena Maricic, Dragan Vasiljevic, Viktor Selakovic","doi":"10.18502/ijph.v53i10.16702","DOIUrl":"10.18502/ijph.v53i10.16702","url":null,"abstract":"<p><strong>Background: </strong>Social networks and support have an independent and strong influence on health and quality of life at all stages of the life cycle, especially in the elderly. We aimed to determine the level of social support among the elderly population of the Republic of Serbia.</p><p><strong>Methods: </strong>The survey is part of the fourth Health survey of the population of Serbia, which was conducted in 2019 by the Republic Institute of Statistics with the Institute for Public Health of Serbia \"Dr. Milan Jovanović Batut\" and the Ministry of Health of the Republic of Serbia. The research instrument was standardized questionnaires constructed in accordance with the European Health Interview Survey (EHIS, wave3) and the social support score (Oslo-3 Social Support Scale). For the purposes of this research, data on the population aged 65 and over were used.</p><p><strong>Results: </strong>In terms of social support, 85.8% of respondents had bad , 13.9% moderate and 0.3% strong. Univariate regression analysis determined that respondents from the territory of Vojvodina had a 1.6 times higher chance of poor social support compared to respondents from southern and eastern Serbia. The probability of bad social support was 1.5 times higher in persons who were never married/cohabiting, persons with secondary education were at 1.6 times higher risk of poor social support compared to persons with higher education. Inactive persons had poor social support 1.4 times more often than employed persons, as well as persons with comorbidities (OR=1.218).</p><p><strong>Conclusion: </strong>These researches are of great importance for public health because it provides valuable data for the creation of interventions that will intensify activities related to providing adequate social support to the elderly.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 10","pages":"2251-2259"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"4-Methyl-N-(Piperidin-1-Ylmethylene) Benzenesulfonamide (PMSA) Promotes Ferroptosis of Tumor Cells by Targeting the <i>KEAP1-NRF2-GPX4</i> Axis.","authors":"Bingchun Sun, Guangyu Zhao, Ligang Zhang, Jianji Hou, Binhua Wu","doi":"10.18502/ijph.v53i10.16705","DOIUrl":"10.18502/ijph.v53i10.16705","url":null,"abstract":"<p><strong>Background: </strong>We aimed to investigate the effect of 4-methyl-N-(piperidin-1-ylmethylene) benzenesulfonamide (PMSA) on tumor cell proliferation, migration, ferroptosis, and the potential molecular mechanism of ferroptosis in tumor cells.</p><p><strong>Methods: </strong>PMSA was produced in the marine biomedical research institute of Guangdong Medical University (Zhanjiang, China) and used for tumor cells treatment. MTT and cell colony formation assays were used to measure the inhibition of tumor cell proliferation, the scratch assay was used to identified the suppression of tumor cell migration, the death of tumor cells was measured by Annexin-V-FITC/PI staining, the level of ferroptosis-relative lipid ROS in tumor cells was measured by flow cytometry and MDA detection kit, and the expression of ferroptosis-relative protein was measured by Western blot. The Discovery Studio system was used for molecular docking and the binding ability was measured by cellular thermal shift assay.</p><p><strong>Results: </strong>The PMSA we produced inhibited tumor cell proliferation, colony formation, migration and triggered cell death, and Fer-1 could reverse these effects. The amount of ROS and MDA levels in tumor cells was also markedly raised by PMSA. PMSA treatment significantly reduced the expression of SLC7A11/XCT, <i>NRF2</i>, and <i>GPX4</i> in tumor cells. The phosphorylation level of <i>NRF2</i> was also decreased. Through molecular docking, it was discovered that PMSA could bind to <i>NRF2</i> and thereby block its activity.</p><p><strong>Conclusion: </strong>The <i>KEAP1</i>-<i>NRF2</i>-<i>GPX4</i> axis was the target of PMSA's anti-tumor action, which results in ferroptosis of tumor cells. This demonstrated that the compound has the potential to be used as a candidate for anti-tumor drugs.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 10","pages":"2279-2289"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Benefits and Applications of <i>Lactobacillus plantarum</i> in Food and Health: A Narrative Review.","authors":"Davood Zare, Hadis Aryaee, Saeed Mirdamadi, Faezeh Shirkhan","doi":"10.18502/ijph.v53i10.16698","DOIUrl":"10.18502/ijph.v53i10.16698","url":null,"abstract":"<p><p><i>Lactobacillus plantarum</i> is a type of gram-positive lactic acid bacteria. This bacterium is considered a safe probiotic and, many applications and benefits including prolonging food shelf-life, enhancing antioxidant activity, improving food flavor characteristics and antimicrobial activities in the food industry, and application as a potential starter for dairy products have been attributed to it. Various studies have also emphasized its health-giving properties. As a result, the features and wide application of this bacterium, as well as the safety of <i>L. plantarum</i> and its strains, have made it a popular probiotic in the food and medical industries. Thus, in the present study keywords including <i>L. plantarum</i> and <i>Lactiplantibacillus plantarum</i> along with application, benefits, food, health, anti-oxidant, anti-diabetic, anti-obesity, anti-inflammatory, antiviral, and anti-depression were searched in databases of PubMed, Scopus, Web of Science, Sience direct and Google Scholar with no time restriction. Then, important features, benefits, and uses of <i>L. plantarum</i> were categorized and discussed. The ability of <i>L. plantarum</i> on the food such as prolonging food shelf-life, enhancing antioxidant activity, improving food flavor characteristics and antimicrobial activities in the food industry, and as a potential starter for dairy products is effective. In addition, several studies have emphasized of <i>L. plantarum</i> health-giving properties.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 10","pages":"2201-2213"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557752/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of <i>ADIPOQ</i> Single Nucleotide Polymorphisms (SNPs) with Obesity Risk in Different Populations: A Systematic Review and Analysis.","authors":"Nurgul Sikhayeva, Akmaral Nursafina, Aidana Satayeva, Talgat Utupov","doi":"10.18502/ijph.v53i10.16696","DOIUrl":"10.18502/ijph.v53i10.16696","url":null,"abstract":"<p><strong>Background: </strong>Thirty-two single nucleotide polymorphisms (SNPs) are commonly found in <i>ADIPOQ</i>. APN levels are decreased in obesity, and SNPs of the <i>ADIPOQ</i> gene affecting APN have varying associations with the development of obesity in different populations. This systematic review and meta-analysis aimed to investigate the association of SNPs in <i>ADIPOQ</i> with the risk of obesity development in various populations.</p><p><strong>Methods: </strong>A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist date up to Feb 2023. We used the Newcastle-Ottawa scale to find out if a study fit the main criteria for submission and to assess the data quality of the articles included in the systematic review and meta-analysis. Odds ratios (OR) and 95% confidence intervals (CI) were calculated via Review Manager (RM) V.5.4 to estimate the connection between <i>ADIPOQ</i> polymorphic qualities of a gene and the risk of developing obesity.</p><p><strong>Results: </strong>The present study analysed the association between <i>ADIPOQ</i> polymorphisms (rs1501299, rs2241766, rs266729, rs822393, and rs822396) and obesity risk and suggested that APN is partially responsible for the emergence of obesity and increases its risk.</p><p><strong>Conclusion: </strong>It is important to take into account several limitations of this meta-analysis when evaluating the findings. First off, even though we looked through numerous databases for all relevant papers, there is a chance we overlooked some. Our capacity to arrive at more firm conclusions was further hampered by the small number of papers that made up our meta-analysis. The most current data, however, are presented in this study since it used newly published data to perform a meta-analysis and evaluate the relationship between ADIPOQ polymorphisms and obesity.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 10","pages":"2180-2190"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of the Package of Essential Non-Communicable (PEN) Disease Interventions in Low-Resource Settings: A Systematic Review.","authors":"Mina Aminpour, Aidin Aryankhesal, Asgar Aghaei Hashjin, Hamid Pourasghari","doi":"10.18502/ijph.v53i10.16700","DOIUrl":"10.18502/ijph.v53i10.16700","url":null,"abstract":"<p><strong>Background: </strong>To deal with the rising prevalence and death rate of non-communicable diseases, the WHO designed a package of essential interventions for non-communicable diseases for low- and middle-income countries. This review aimed to identify the barriers and facilitators of the implementation of this program.</p><p><strong>Methods: </strong>The electronic databases of PubMed, Scopus, Web of Science, Cochrane Library, and Scientific Information Database (SID) were searched for papers without a time limit at the end of Dec 2020. Only English and Persian languages were considered. The PRISMA guideline was consulted.</p><p><strong>Results: </strong>Overall, 15 articles were selected for the final analysis out of 404 initially retrieved ones, based on inclusion/exclusion criteria and quality assessment. Thirteen articles had good quality, while 2 articles were of fair quality. Studies were published during 2014-2020. Thematic analysis was used to make sense of papers so that barriers and facilitators were categorized within 2 main themes and 7 sub-themes. Certain organizational factors including human resources, service delivery, structure, leadership/governance, data and information, resources, and financing were identified as barriers and facilitators. Knowledge and culture, and economic and social factors were identified as contextual factors.</p><p><strong>Conclusion: </strong>By considering the factors identified in this study, policymakers and health system managers can be more successful in implementing this WHO PEN and similar packages.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 10","pages":"2226-2238"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}