发布求助
文献互助 智能选刊 最新文献

Nature Structural & Molecular Biology最新文献

筛选
英文 中文
Focus on ubiquitylation and protein degradation 关注泛素化和蛋白质降解
IF 10.1 1区 生物学
Nature Structural & Molecular Biology Pub Date : 2025-09-16 DOI: 10.1038/s41594-025-01672-9
{"title":"Focus on ubiquitylation and protein degradation","authors":"","doi":"10.1038/s41594-025-01672-9","DOIUrl":"10.1038/s41594-025-01672-9","url":null,"abstract":"We highlight primary research and commissioned content that delve into the biology of ubiquitylation and degradation mechanisms.","PeriodicalId":49141,"journal":{"name":"Nature Structural & Molecular Biology","volume":"32 9","pages":"1581-1581"},"PeriodicalIF":10.1,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41594-025-01672-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145067758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A snapshot of proteostasis in human oocytes 人类卵母细胞蛋白质静止的快照
IF 10.1 1区 生物学
Nature Structural & Molecular Biology Pub Date : 2025-09-09 DOI: 10.1038/s41594-025-01679-2
Dimitris Typas
{"title":"A snapshot of proteostasis in human oocytes","authors":"Dimitris Typas","doi":"10.1038/s41594-025-01679-2","DOIUrl":"10.1038/s41594-025-01679-2","url":null,"abstract":"","PeriodicalId":49141,"journal":{"name":"Nature Structural & Molecular Biology","volume":"32 9","pages":"1591-1591"},"PeriodicalIF":10.1,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145018078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The rise of ADP-ribose–ubiquitin adp -核糖泛素的上升
IF 10.1 1区 生物学
Nature Structural & Molecular Biology Pub Date : 2025-09-08 DOI: 10.1038/s41594-025-01651-0
Chatrin Chatrin, Kang Zhu, Ivan Ahel
{"title":"The rise of ADP-ribose–ubiquitin","authors":"Chatrin Chatrin, Kang Zhu, Ivan Ahel","doi":"10.1038/s41594-025-01651-0","DOIUrl":"10.1038/s41594-025-01651-0","url":null,"abstract":"Post-translational modifications show mechanistic crosstalk, exemplified by the ADP-ribose–ubiquitin hybrid signal, in which one post-translational modification modifies another. This Comment highlights its discovery, mechanistic basis and functional consequences, and outlines critical questions for understanding this emerging signaling paradigm.","PeriodicalId":49141,"journal":{"name":"Nature Structural & Molecular Biology","volume":"32 9","pages":"1582-1585"},"PeriodicalIF":10.1,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145009278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Author Correction: HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly 作者更正：HIV-1依赖于其未成熟的晶格来招募IP6用于成熟的衣壳组装。
IF 10.1 1区 生物学
Nature Structural & Molecular Biology Pub Date : 2025-08-29 DOI: 10.1038/s41594-025-01667-6
Nadine Renner, Alex Kleinpeter, Donna L. Mallery, Anna Albecka, K. M. Rifat Faysal, Till Böcking, Adolfo Saiardi, Eric O. Freed, Leo C. James
{"title":"Author Correction: HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly","authors":"Nadine Renner, Alex Kleinpeter, Donna L. Mallery, Anna Albecka, K. M. Rifat Faysal, Till Böcking, Adolfo Saiardi, Eric O. Freed, Leo C. James","doi":"10.1038/s41594-025-01667-6","DOIUrl":"10.1038/s41594-025-01667-6","url":null,"abstract":"","PeriodicalId":49141,"journal":{"name":"Nature Structural & Molecular Biology","volume":"32 9","pages":"1839-1839"},"PeriodicalIF":10.1,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41594-025-01667-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144961744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Author Correction: Structural basis of the histone ubiquitination read–write mechanism of RYBP–PRC1 作者更正：RYBP-PRC1组蛋白泛素化读写机制的结构基础。
IF 10.1 1区 生物学
Nature Structural & Molecular Biology Pub Date : 2025-08-27 DOI: 10.1038/s41594-025-01674-7
Maria Ciapponi, Elena Karlukova, Sven Schkölziger, Christian Benda, Jürg Müller
{"title":"Author Correction: Structural basis of the histone ubiquitination read–write mechanism of RYBP–PRC1","authors":"Maria Ciapponi, Elena Karlukova, Sven Schkölziger, Christian Benda, Jürg Müller","doi":"10.1038/s41594-025-01674-7","DOIUrl":"10.1038/s41594-025-01674-7","url":null,"abstract":"","PeriodicalId":49141,"journal":{"name":"Nature Structural & Molecular Biology","volume":"32 9","pages":"1840-1840"},"PeriodicalIF":10.1,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144961736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Author Correction: A critical period of translational control during brain development at codon resolution 作者更正：密码子解析时大脑发育中翻译控制的关键时期。
IF 10.1 1区 生物学
Nature Structural & Molecular Biology Pub Date : 2025-08-27 DOI: 10.1038/s41594-025-01675-6
Dermot Harnett, Mateusz C. Ambrozkiewicz, Ulrike Zinnall, Alexandra Rusanova, Ekaterina Borisova, Amelie N. Drescher, Marta Couce-Iglesias, Gabriel Villamil, Rike Dannenberg, Koshi Imami, Agnieszka Münster-Wandowski, Beatrix Fauler, Thorsten Mielke, Matthias Selbach, Markus Landthaler, Christian M. T. Spahn, Victor Tarabykin, Uwe Ohler, Matthew L. Kraushar
{"title":"Author Correction: A critical period of translational control during brain development at codon resolution","authors":"Dermot Harnett, Mateusz C. Ambrozkiewicz, Ulrike Zinnall, Alexandra Rusanova, Ekaterina Borisova, Amelie N. Drescher, Marta Couce-Iglesias, Gabriel Villamil, Rike Dannenberg, Koshi Imami, Agnieszka Münster-Wandowski, Beatrix Fauler, Thorsten Mielke, Matthias Selbach, Markus Landthaler, Christian M. T. Spahn, Victor Tarabykin, Uwe Ohler, Matthew L. Kraushar","doi":"10.1038/s41594-025-01675-6","DOIUrl":"10.1038/s41594-025-01675-6","url":null,"abstract":"","PeriodicalId":49141,"journal":{"name":"Nature Structural & Molecular Biology","volume":"32 9","pages":"1838-1838"},"PeriodicalIF":10.1,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144961726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Publisher Correction: Cytoplasmic PXR regulates glucose metabolism by binding mRNAs and modulating their stability 出版者更正：细胞质PXR通过结合mrna并调节其稳定性来调节葡萄糖代谢。
IF 10.1 1区 生物学
Nature Structural & Molecular Biology Pub Date : 2025-08-18 DOI: 10.1038/s41594-025-01668-5
Xiaofei Wang, Zehua Wang, Sihan Li, Dhamotharan Pattarayan, Yifei Wang, Jingchen Zhai, Yu Zhang, Haolin Wang, Meishu Xu, Junjie Zhu, Junmei Wang, Xiaochao Ma, Sridhar Mani, Wen Xie, Min Zhang, Da Yang
{"title":"Publisher Correction: Cytoplasmic PXR regulates glucose metabolism by binding mRNAs and modulating their stability","authors":"Xiaofei Wang, Zehua Wang, Sihan Li, Dhamotharan Pattarayan, Yifei Wang, Jingchen Zhai, Yu Zhang, Haolin Wang, Meishu Xu, Junjie Zhu, Junmei Wang, Xiaochao Ma, Sridhar Mani, Wen Xie, Min Zhang, Da Yang","doi":"10.1038/s41594-025-01668-5","DOIUrl":"10.1038/s41594-025-01668-5","url":null,"abstract":"","PeriodicalId":49141,"journal":{"name":"Nature Structural & Molecular Biology","volume":"32 9","pages":"1840-1840"},"PeriodicalIF":10.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41594-025-01668-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A structural switch reveals how to disarm USP30 and unlock mitophagy 一个结构开关揭示了如何解除USP30并解锁有丝分裂
IF 10.1 1区 生物学
Nature Structural & Molecular Biology Pub Date : 2025-07-25 DOI: 10.1038/s41594-025-01640-3
Julia C. Fitzgerald, Anja Bremm
{"title":"A structural switch reveals how to disarm USP30 and unlock mitophagy","authors":"Julia C. Fitzgerald, Anja Bremm","doi":"10.1038/s41594-025-01640-3","DOIUrl":"10.1038/s41594-025-01640-3","url":null,"abstract":"A recent high-resolution structure of USP30 bound to a selective inhibitor identifies a cryptic binding pocket formed through a conformational switch in the catalytic domain of the enzyme. This mechanistic insight opens a door to structure-guided design of mitophagy-enhancing compounds.","PeriodicalId":49141,"journal":{"name":"Nature Structural & Molecular Biology","volume":"32 9","pages":"1586-1588"},"PeriodicalIF":10.1,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144702080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Q&A with Yael David and Charles Rice on using chromatin biology to understand hepatitis 雅艾尔·大卫和查尔斯·赖斯关于用染色质生物学来理解肝炎的问答
IF 10.1 1区 生物学
Nature Structural & Molecular Biology Pub Date : 2025-07-17 DOI: 10.1038/s41594-025-01613-6
Dimitris Typas
{"title":"Q&A with Yael David and Charles Rice on using chromatin biology to understand hepatitis","authors":"Dimitris Typas","doi":"10.1038/s41594-025-01613-6","DOIUrl":"10.1038/s41594-025-01613-6","url":null,"abstract":"Yael David leads her lab focused on studying the fundamental mechanisms of epigenetic regulation of transcription at Memorial Sloan Kettering Cancer Center, and Charles Rice is the Maurice R. and Corinne P. Greenberg Professor in Virology at The Rockefeller University in New York City. We contacted them to discuss a recent publication by the David lab that substantially advances the molecular understanding of and, potentially, the clinical arsenal against infection with hepatitis B virus (HBV).","PeriodicalId":49141,"journal":{"name":"Nature Structural & Molecular Biology","volume":"32 8","pages":"1319-1321"},"PeriodicalIF":10.1,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144645529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A marker for sterol-dependent metastatic tropism 胆固醇依赖性转移性的标志物
IF 10.1 1区 生物学
Nature Structural & Molecular Biology Pub Date : 2025-07-11 DOI: 10.1038/s41594-025-01626-1
Yuqi Wang, Xi Wang, Charles J. David, Yilong Zou
{"title":"A marker for sterol-dependent metastatic tropism","authors":"Yuqi Wang, Xi Wang, Charles J. David, Yilong Zou","doi":"10.1038/s41594-025-01626-1","DOIUrl":"10.1038/s41594-025-01626-1","url":null,"abstract":"How metabolic fitness in cancer clones is established and selected during dissemination and colonization remains enigmatic. A study in Nature now shows that disseminated pancreatic cancer cells bifurcate to seed the lung or liver on the basis of PCSK9 levels and the availability of microenvironmental cholesterol.","PeriodicalId":49141,"journal":{"name":"Nature Structural & Molecular Biology","volume":"32 8","pages":"1331-1333"},"PeriodicalIF":10.1,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144603103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信