{"title":"雅艾尔·大卫和查尔斯·赖斯关于用染色质生物学来理解肝炎的问答","authors":"Dimitris Typas","doi":"10.1038/s41594-025-01613-6","DOIUrl":null,"url":null,"abstract":"Yael David leads her lab focused on studying the fundamental mechanisms of epigenetic regulation of transcription at Memorial Sloan Kettering Cancer Center, and Charles Rice is the Maurice R. and Corinne P. Greenberg Professor in Virology at The Rockefeller University in New York City. We contacted them to discuss a recent publication by the David lab that substantially advances the molecular understanding of and, potentially, the clinical arsenal against infection with hepatitis B virus (HBV).","PeriodicalId":18822,"journal":{"name":"Nature structural & molecular biology","volume":"24 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Q&A with Yael David and Charles Rice on using chromatin biology to understand hepatitis\",\"authors\":\"Dimitris Typas\",\"doi\":\"10.1038/s41594-025-01613-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Yael David leads her lab focused on studying the fundamental mechanisms of epigenetic regulation of transcription at Memorial Sloan Kettering Cancer Center, and Charles Rice is the Maurice R. and Corinne P. Greenberg Professor in Virology at The Rockefeller University in New York City. We contacted them to discuss a recent publication by the David lab that substantially advances the molecular understanding of and, potentially, the clinical arsenal against infection with hepatitis B virus (HBV).\",\"PeriodicalId\":18822,\"journal\":{\"name\":\"Nature structural & molecular biology\",\"volume\":\"24 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-07-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature structural & molecular biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1038/s41594-025-01613-6\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature structural & molecular biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1038/s41594-025-01613-6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
Yael David在纪念斯隆凯特琳癌症中心领导她的实验室专注于研究表观遗传调控转录的基本机制，Charles Rice是纽约市洛克菲勒大学病毒学的Maurice R.和Corinne P. Greenberg教授。我们联系了他们，讨论了David实验室最近发表的一篇文章，该文章大大提高了对乙型肝炎病毒（HBV）感染的分子认识，并有可能提高临床武器库。
Q&A with Yael David and Charles Rice on using chromatin biology to understand hepatitis
Yael David leads her lab focused on studying the fundamental mechanisms of epigenetic regulation of transcription at Memorial Sloan Kettering Cancer Center, and Charles Rice is the Maurice R. and Corinne P. Greenberg Professor in Virology at The Rockefeller University in New York City. We contacted them to discuss a recent publication by the David lab that substantially advances the molecular understanding of and, potentially, the clinical arsenal against infection with hepatitis B virus (HBV).
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