Social Science & Medicine最新文献

Overcoming the "valleys of death" in advanced therapies: The role of finance.

IF 4.9 2区医学

Social Science & Medicine Pub Date : 2024-12-17 DOI: 10.1016/j.socscimed.2024.117639

Simona Cosma, Stefano Cosma, Daniela Pennetta, Giuseppe Rimo

{"title":"Overcoming the \"valleys of death\" in advanced therapies: The role of finance.","authors":"Simona Cosma, Stefano Cosma, Daniela Pennetta, Giuseppe Rimo","doi":"10.1016/j.socscimed.2024.117639","DOIUrl":"https://doi.org/10.1016/j.socscimed.2024.117639","url":null,"abstract":"Advanced therapies are the frontier of medical research and have a relevant therapeutic potential and a profound social value. Despite this, their funding is hindered by many heterogeneous factors that obstruct their translation and survival on the market, even when approved and effective. Using an extensive bibliometric and systematic review of 174 articles published between 2001 and 2023, this study aims to identify the factors hindering the financing of advanced therapies and suggest future research lines to overcome the biomedical and economic \"valleys of death\". This study is the first review focused on advanced therapies from a financial perspective, and it contributes to advancing scientific knowledge in several ways. First, it highlights that finance academics paid little attention to the topic and most of their contributions are now outdated; therefore, there is the need to explore the new opportunities and solutions offered by financial innovation and the application of new technologies to financial activity. Second, it asks for an interdisciplinary approach to exploring advanced therapies' barriers from a holistic and process perspective and exploiting the social value generated by the development of innovative therapies. Finally, it analyzes the obstacles and value destroyed by the absence of an organic and coordinated process of public intervention, underscoring the imperative for further research to explore new public-private financial models and risk-sharing schemes and extend evaluation models by integrating financial and social value logic.","PeriodicalId":49122,"journal":{"name":"Social Science & Medicine","volume":"366 ","pages":"117639"},"PeriodicalIF":4.9,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to 'When reality knocks on the door. The effect of conspiracy beliefs on COVID-19 vaccine acceptance and the moderating role of experience with the virus' [Soc. Sci. Med. Volume 356, September 2024, 117149]. 当现实来敲门时。阴谋论信念对 COVID-19 疫苗接受度的影响及病毒感染经验的调节作用"[《社会科学-医学》第 356 卷，2024 年 9 月，117149 页]。

IF 4.9 2区医学

Social Science & Medicine Pub Date : 2024-12-16 DOI: 10.1016/j.socscimed.2024.117618

Ádám Stefkovics, Péter Krekó, Júlia Koltai

引用次数: 0

Corrigendum to "The effect of public tolerance towards corruptive behaviour on healthcare efficiency and equity - The case of the UK's COVID-19 vaccination programme" [Soc. Sci. Med. Volume 361, November 2024, 117180]. 公众对腐败行为的容忍度对医疗效率和公平的影响--以英国 COVID-19 疫苗接种计划为例"[《社会科学与医学》第 361 卷，2024 年 11 月，第 117180 期]更正。

IF 4.9 2区医学

Social Science & Medicine Pub Date : 2024-12-15 DOI: 10.1016/j.socscimed.2024.117617

Franziska Sohns, Stefano Ghinoi, Magdalena Langosch

引用次数: 0

The unintended effects of a large minimum wage increase on health: Evidence from South Korea.

IF 4.9 2区医学

Social Science & Medicine Pub Date : 2024-12-15 DOI: 10.1016/j.socscimed.2024.117626

Jung Hyun Kim, Marc Suhrcke, Anja K Leist

{"title":"The unintended effects of a large minimum wage increase on health: Evidence from South Korea.","authors":"Jung Hyun Kim, Marc Suhrcke, Anja K Leist","doi":"10.1016/j.socscimed.2024.117626","DOIUrl":"https://doi.org/10.1016/j.socscimed.2024.117626","url":null,"abstract":"The 2018 minimum wage increase in South Korea was a major policy change that impacted employment and labour productivity, but its effects on health have not yet been explored. The minimum wage was increased by 16.4% in January 2018, marking the largest increase over two decades and a substantial increase by international standards. While this policy change was a promise of the then-new government, the magnitude of its increase was unexpected. Using a difference-in-differences design with data from the 2016 and 2018 Korean Longitudinal Study on Aging, this study focuses on individuals targeted by the minimum wage policy, particularly older adults earning the minimum wage. Unexpectedly, our results indicate a statistically significant decrease in cognitive function within the targeted group, following the minimum wage hike. However, we did not observe any significant changes in self-reported health. Importantly, for the period 2014 and 2016, when the minimum wage increase was relatively modest, we found positive effects on cognitive health and no negative effects on self-reported health, suggesting that negative effects on cognition emerged only with the large minimum wage increase in 2018. These perhaps unexpected findings may be explained by a significant reduction in the working hours of the targeted group.","PeriodicalId":49122,"journal":{"name":"Social Science & Medicine","volume":"365 ","pages":"117626"},"PeriodicalIF":4.9,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamic associations between daily acting with awareness and emotion regulation in individuals living with the effects of a stroke.

IF 4.9 2区医学

Social Science & Medicine Pub Date : 2024-12-14 DOI: 10.1016/j.socscimed.2024.117635

Nathaniel J Johnson, Hali Kil, Theresa Pauly, Maureen C Ashe, Kenneth M Madden, Rachel A Murphy, Wolfgang Linden, Denis Gerstorf, Christiane A Hoppmann

{"title":"Dynamic associations between daily acting with awareness and emotion regulation in individuals living with the effects of a stroke.","authors":"Nathaniel J Johnson, Hali Kil, Theresa Pauly, Maureen C Ashe, Kenneth M Madden, Rachel A Murphy, Wolfgang Linden, Denis Gerstorf, Christiane A Hoppmann","doi":"10.1016/j.socscimed.2024.117635","DOIUrl":"https://doi.org/10.1016/j.socscimed.2024.117635","url":null,"abstract":"One often-overlooked consequence of stroke is a deficit in emotion regulation. Acting with awareness in everyday life has been found to support emotion regulation but it is an open question whether such associations generalize to stroke populations. Factors associated with emotion regulation in stroke survivors are key to inform rehabilitation efforts. This study used up to 14 repeated daily life assessments to examine everyday associations between acting with awareness and affect in a sample of 86 community-dwelling adults post-stroke living in Southern British Columbia, Canada (Mage = 68.70, SD = 10.56; range = 33-88; 26.7% female; 63.8% with less than college degree). Multilevel models examined the extent to which daily acting with awareness, previous-day negative affect, and previous-day positive affect were associated with daily negative and positive affect. Multilevel models operationally defined emotion regulation as affect carry-over, the extent to which affect lingered from one day to the next. Results revealed that on days when acting with awareness was elevated, negative affect did not carry over from the previous day, suggesting greater emotion regulation. Additionally, on days when acting with awareness was elevated, positive affect was maintained from day to day, indicating lingering positivity effects. Future research should expand upon our correlational findings, as the opposite causal direction might also hold-affect may increase the likelihood of acting with awareness. Overall, findings suggest that mindfulness-based interventions after stroke might benefit from a greater focus on daily acting with awareness.","PeriodicalId":49122,"journal":{"name":"Social Science & Medicine","volume":"366 ","pages":"117635"},"PeriodicalIF":4.9,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of low employment quality with cigarette smoking, smoking initiation, and smoking cessation: A 16-year longitudinal study in South Korea.

IF 4.9 2区医学

Social Science & Medicine Pub Date : 2024-12-12 DOI: 10.1016/j.socscimed.2024.117629

Seong-Uk Baek, Yu-Min Lee, Jong-Uk Won, Jin-Ha Yoon

{"title":"Association of low employment quality with cigarette smoking, smoking initiation, and smoking cessation: A 16-year longitudinal study in South Korea.","authors":"Seong-Uk Baek, Yu-Min Lee, Jong-Uk Won, Jin-Ha Yoon","doi":"10.1016/j.socscimed.2024.117629","DOIUrl":"https://doi.org/10.1016/j.socscimed.2024.117629","url":null,"abstract":"This study explored the association between multidimensional aspects of employment quality and smoking habits. This study included the wage workers in the Korean Labour and Income Panel Study, 2005-2021 (n = 16,188; observations = 92,954). The employment quality was constructed using a multidimensional approach encompassing three dimensions: employment insecurity, income inadequacy, and a lack of rights and protection. The outcome was current smoking in the same year as exposure to employment quality, as well as the incidence of smoking initiation and cessation in the subsequent year. A generalized estimating equation was used for repeated measures analysis to estimate the odds ratio (OR) and 95% confidence intervals (CIs). Compared with those with the highest employment quality, the odds of smoking cessation were lower among those with the low employment quality (OR: 0.81, 95% CI: 0.68-0.95) and those with the lowest employment quality (OR: 0.76, 95% CI: 0.61-0.95). While a comparable relationship was found among males, the correlation in the female sample was unclear. Concurrent smoking status and smoking initiation exhibited no clear associations with overall employment quality in both male and female samples. For individual employment quality indicators, daily employment showed a negative association with the odds of smoking cessation. Therefore, this study suggests that policy interventions aimed at enhancing the employment quality of workers are warranted to reduce smoking rates.","PeriodicalId":49122,"journal":{"name":"Social Science & Medicine","volume":"366 ","pages":"117629"},"PeriodicalIF":4.9,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tuberculosis treatment and undernutrition on Daru Island, Papua New Guinea: A qualitative exploration of a local foodscape.

IF 4.9 2区医学

Social Science & Medicine Pub Date : 2024-12-12 DOI: 10.1016/j.socscimed.2024.117631

A Persson, P Jops, J Cowan, M Kupul, R Nake Trumb, S S Majumdar, S Islam, H Nindil, W Pomat, S Bell, G Marks, M Bauri, S M Graham, A Kelly-Hanku

{"title":"Tuberculosis treatment and undernutrition on Daru Island, Papua New Guinea: A qualitative exploration of a local foodscape.","authors":"A Persson, P Jops, J Cowan, M Kupul, R Nake Trumb, S S Majumdar, S Islam, H Nindil, W Pomat, S Bell, G Marks, M Bauri, S M Graham, A Kelly-Hanku","doi":"10.1016/j.socscimed.2024.117631","DOIUrl":"https://doi.org/10.1016/j.socscimed.2024.117631","url":null,"abstract":"A substantial proportion of people with tuberculosis (TB)-one of the world's deadliest infectious diseases-live in resource-poor, food insecure settings. It is widely recognised that undernutrition significantly heightens vulnerability to TB, as well as contributes to poor treatment adherence and outcomes. However, more attention is needed to understand what shapes food insecurity and undernutrition in a particular setting. We use the concept of \"foodscapes\" to explore the distinct food environment on Daru Island, a recognised \"hotspot\" for multidrug-resistant TB in the Western Province of Papua New Guinea. Drawing on 128 qualitative interviews and 10 focus groups (conducted July 2019 and July 2020) with people with TB, family members, healthcare providers, community leaders and other stakeholders, we seek to elucidate the critical entwinement of food insecurity, people with TB, and their treatment experiences on Daru Island. We argue that potential solutions need to focus on the social and structural conditions that contribute to undernutrition in the first place, rather than on undernutrition itself.","PeriodicalId":49122,"journal":{"name":"Social Science & Medicine","volume":"365 ","pages":"117631"},"PeriodicalIF":4.9,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A network comparison analysis of socio-ecological protective and risk factors of depression between Chinese urban and rural adolescents.

IF 4.9 2区医学

Social Science & Medicine Pub Date : 2024-12-11 DOI: 10.1016/j.socscimed.2024.117628

Xiaoyu Zhuang, Chun Pong Chan, Xue Yang

{"title":"A network comparison analysis of socio-ecological protective and risk factors of depression between Chinese urban and rural adolescents.","authors":"Xiaoyu Zhuang, Chun Pong Chan, Xue Yang","doi":"10.1016/j.socscimed.2024.117628","DOIUrl":"https://doi.org/10.1016/j.socscimed.2024.117628","url":null,"abstract":"Background: Anchoring in the socio-ecological framework and the differential impact theory, the present study pioneered to explore the differential network structures of multilevel risk and protective factors that influence depression among Chinese urban and rural adolescents.Method: A sample of 684 urban adolescents and 1123 rural adolescents completed a battery of self-report questionnaires measuring their depressive symptoms, as well as risk and protective factors at intrapersonal (psychological flexibility, emotion regulation), interpersonal (social support, parental control), and social levels (social capital, stressful life events).Results: Central risk and protective factors in both groups included psychological flexibility, which bridged intrapersonal, interpersonal and social resources, along with social support, social capital, rumination, catastrophizing, and self-blame. Network comparison tests revealed significant differences in the global strength and network structures between the two groups. Rural adolescents showed denser connections between positive refocusing - rumination, positive refocusing - other-blame, refocusing on planning - self-blame, and family support - self-blame, while urban adolescents showed a stronger relationship between rumination - blaming others - depression. Rural adolescents uniquely benefited from a protective loop of reappraisal - social satisfaction - depression.Conclusion: The findings suggest both beneficial and trade-off effects of a denser psychosocial network in adolescents growing up in a high-risk environment. Such results imply that only increasing the number of protective factors (e.g., social resources) may not be sufficient; instead, practical strategies that can neutralize the drawbacks of protective mechanisms may serve as critical strategies in promoting the socio-ecological well-being of adolescents in China and elsewhere.","PeriodicalId":49122,"journal":{"name":"Social Science & Medicine","volume":"365 ","pages":"117628"},"PeriodicalIF":4.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The contribution of childhood adversity to adult socioeconomic gradients in mortality: A Swedish birth cohort analysis.

IF 4.9 2区医学

Social Science & Medicine Pub Date : 2024-12-11 DOI: 10.1016/j.socscimed.2024.117627

Josephine Jackisch, Alyson van Raalte

{"title":"The contribution of childhood adversity to adult socioeconomic gradients in mortality: A Swedish birth cohort analysis.","authors":"Josephine Jackisch, Alyson van Raalte","doi":"10.1016/j.socscimed.2024.117627","DOIUrl":"https://doi.org/10.1016/j.socscimed.2024.117627","url":null,"abstract":"Background: \"Child maltreatment is a leading cause of health inequality\" according to a leading WHO report. This statement is often assumed, yet, the size of the contribution of childhood adversity to the adult socioeconomic gradient in mortality remains unknown. Inequalities in mortality have mostly been investigated by taking adult conditions as a starting point. The objective of this study is to quantify how much of the socioeconomic gradient in adult life expectancy is associated with childhood adversity.Methods: Drawing on a 1953 birth cohort from Stockholm (n = 14 210), we compared inequalities in adult mortality within the full cohort to a counterfactual scenario where individuals with a history of childhood adversity (indicated by involvement with child welfare services) experienced the mortality rates of those achieving the same adult socioeconomic position, but with no history of childhood adversity. The socioeconomic gradient across education and income quintiles (attained by age 29) is measured by the slope index of inequality of temporary life expectancy (ages 29-67).Results: The counterfactual scenario attenuated the education gradient by 40 percent for men and 54 percent for women. Similarly, inequalities by income were reduced in the counterfactual scenario by 49 percent for men and 47 percent for women.Interpretation: These results support that childhood adversity is an important determinant of inequalities in mortality. The size of their contribution is equivalent to established behavioural risk factors. Taking a life course approach might provide important policy entry points to mitigate health inequalities.","PeriodicalId":49122,"journal":{"name":"Social Science & Medicine","volume":"365 ","pages":"117627"},"PeriodicalIF":4.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Age-friendly community environments and the age trajectories of long-term care dependency among Chinese older adults.

IF 4.9 2区医学

Social Science & Medicine Pub Date : 2024-12-10 DOI: 10.1016/j.socscimed.2024.117614

Peng Nie, Qiaoge Li

{"title":"Age-friendly community environments and the age trajectories of long-term care dependency among Chinese older adults.","authors":"Peng Nie, Qiaoge Li","doi":"10.1016/j.socscimed.2024.117614","DOIUrl":"https://doi.org/10.1016/j.socscimed.2024.117614","url":null,"abstract":"In the context of rapid global aging, the importance of age-friendly community environments for promoting healthy aging and \"aging in place\" continues to increase. Using data from the 2011-2020 China Health and Retirement Longitudinal Study, this study investigated the impact of an age-friendly community environment on the age trajectories of late-life long-term care (LTC) dependency among older Chinese adults aged 60+ years. Age-friendly community environments were defined according to three levels (poor, moderate, or good) based on the World Health Organization's age-friendly city and community framework, and LTC dependency was classified as level 1 (high), level 2 (medium), or level 3 (low) according to activities of daily living and instrumental activities of daily living scores. We classified participants into two age trajectory groups according to their level of LTC dependency: early-onset and late-onset groups. We found that an age-friendly community environment, especially a good housing environment, was consistently associated with the probability of having late-onset LTC dependency at any level. Having moderate and good social and employment environments reduced the likelihood of having early-onset level 2 and level 3 LTC dependency. Our mechanism analysis also revealed that age-friendly community environments affect LTC dependency through social participation. Our results may help elucidate the importance of promoting age-friendly community environments to maintain late-life functional ability and support healthy aging.","PeriodicalId":49122,"journal":{"name":"Social Science & Medicine","volume":"365 ","pages":"117614"},"PeriodicalIF":4.9,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0