International Health最新文献_第3页

Women's right to science and health: 30 years on, progress and gaps remain. 妇女享有科学和健康的权利：30年来，进展和差距依然存在。

IF 2.4 4区医学

International Health Pub Date : 2026-09-01 DOI: 10.1093/inthealth/ihag011

Sandrine Hakiza, Silvia Ferazzi

引用次数: 0

Deliberative dialogues in rural South Africa reveal public support and communication challenges in HIV cure research: uMkhanyakude district, KwaZulu-Natal. 南非农村的协商对话揭示了艾滋病毒治疗研究中的公众支持和沟通挑战：夸祖鲁-纳塔尔省uMkhanyakude地区。

IF 2.4 4区医学

International Health Pub Date : 2026-09-01 DOI: 10.1093/inthealth/ihaf131

Rujeko Samanthia Chimukuche, Miliswa Magongo, Qinisile Shandu, Nomathamsanqa Majozi, Ingrid V Bassett, Janet Seeley, Thumbi Ndung'u

{"title":"Deliberative dialogues in rural South Africa reveal public support and communication challenges in HIV cure research: uMkhanyakude district, KwaZulu-Natal.","authors":"Rujeko Samanthia Chimukuche, Miliswa Magongo, Qinisile Shandu, Nomathamsanqa Majozi, Ingrid V Bassett, Janet Seeley, Thumbi Ndung'u","doi":"10.1093/inthealth/ihaf131","DOIUrl":"10.1093/inthealth/ihaf131","url":null,"abstract":"Background: There is a need to build public support for the conduct of HIV cure research. It is important to enhance the public understanding of HIV cure strategies in resource-constrained settings with high HIV prevalence. Adopting deliberative approaches allows information to be shared interactively, building knowledge on the topic and unpacking the complexity of the science.Methods: We conducted deliberative community dialogues in rural KwaZulu-Natal, South Africa, with the Africa Health Research Institute community engagement team and Community Advisory Board members. We discussed the public understanding of 'HIV cure' and current scientific approaches. Detailed written notes were taken in anonymised format. Data were later analysed thematically, with three main themes identified: (i) understanding of HIV cure trials; (ii) HIV scientific procedures; and (iii) HIV cure messaging.Results: Participants' questions and discussion revealed support for research on HIV cure but limited knowledge and understanding. Participants had questions about trial procedures, risks of antiretroviral therapy interruptions, efficacy, cost and monitoring of viral loads. There is need for simple, accessible language about the complex science to avoid misunderstanding among community members.Conclusion: On going challenges in effectively communicating complex scientific concepts highlight the importance of ongoing community engagement and education in HIV cure research.","PeriodicalId":49060,"journal":{"name":"International Health","volume":" ","pages":"726-733"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12966267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145514701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimicrobial resistance analysis of Klebsiella pneumoniae bloodstream infections based on a random forest algorithm: a longitudinal study based on data from tertiary hospitals in China from 2012 to 2023. 基于随机森林算法的肺炎克雷伯菌血流感染耐药性分析——基于2012 - 2023年中国三级医院数据的纵向研究

IF 2.4 4区医学

International Health Pub Date : 2026-09-01 DOI: 10.1093/inthealth/ihaf158

Na Wang, AiLing Hu, Zexin Wang, Xiaojie Yu, Ying Wei, PingPing Song

{"title":"Antimicrobial resistance analysis of Klebsiella pneumoniae bloodstream infections based on a random forest algorithm: a longitudinal study based on data from tertiary hospitals in China from 2012 to 2023.","authors":"Na Wang, AiLing Hu, Zexin Wang, Xiaojie Yu, Ying Wei, PingPing Song","doi":"10.1093/inthealth/ihaf158","DOIUrl":"10.1093/inthealth/ihaf158","url":null,"abstract":"Background: Bloodstream infections (BSIs) caused by Klebsiella pneumoniae pose a significant global health burden, complicated by rising antimicrobial resistance (AMR). This study aimed to characterize resistance patterns, identify predictors of carbapenem resistance, and develop a machine learning model to predict patient outcomes.Methods: In a retrospective analysis of 109 279 K. pneumoniae BSIs from tertiary hospitals in China (2012-2023), 11 000 isolates underwent whole-genome sequencing (WGS) and antimicrobial susceptibility testing. Cox proportional hazards and logistic regression models identified predictors of 30-day mortality and carbapenem-resistant K. pneumoniae (CRKP), respectively. A random forest model predicted AMR trends and outcomes, evaluated by accuracy, precision, recall, and ROC-AUC using R Studio (R Studio, Inc., Boston, MA, USA).Results: Carbapenem resistance occurred in 32.3% of isolates, with rates of 41.9% for third-generation cephalosporins and 41.2% for fluoroquinolones. Among sequenced isolates, ST11 with blaKPC was the dominant CRKP genotype (12.0%). blaKPC (OR 3.97, 95% CI 3.10-5.11) and blaNDM (OR 2.80, 95% CI 2.07-3.71) strongly predicted carbapenem resistance; ICU admission predicted 30-day mortality (HR 2.10, 95% CI 1.80-2.46, p<0.001). Mortality was higher in CRKP (40.2%) vs. susceptible cases (21.5%). The random forest model achieved 89.2% accuracy and 0.92 ROC-AUC, with drug share, age, and CRKP status as top predictors.Conclusions: CRKP, especially ST11-blaKPC, drives excess mortality. Key predictors highlight the urgency for enhanced AMR surveillance and targeted therapy.","PeriodicalId":49060,"journal":{"name":"International Health","volume":" ","pages":"773-781"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13530284/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145913727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visual acuity outcome and complications of cataract surgery in Nigeria: a systematic review and meta-analysis. 尼日利亚白内障手术的视力结果和并发症：一项系统回顾和荟萃分析。

IF 2.4 4区医学

International Health Pub Date : 2026-09-01 DOI: 10.1093/inthealth/ihaf161

Saudat Garba Habib, Abdullahi Idris, Fatimah Isma'il Tsiga-Ahmed, Clare Gilbert

{"title":"Visual acuity outcome and complications of cataract surgery in Nigeria: a systematic review and meta-analysis.","authors":"Saudat Garba Habib, Abdullahi Idris, Fatimah Isma'il Tsiga-Ahmed, Clare Gilbert","doi":"10.1093/inthealth/ihaf161","DOIUrl":"10.1093/inthealth/ihaf161","url":null,"abstract":"This study estimated the pooled prevalence of visual acuity (VA) outcomes and potentially blinding cataract surgery complications in Nigeria. Ethical clearance was waived by the Ethical Review Board of the Kano State Ministry of Health. We searched PubMed, African journals online, Embase, MEDLINE and Google Scholar to identify relevant studies from January 1990 to February 2025. Data on presenting and best-corrected visual acuities at ≥6 weeks after cataract surgery, intraoperative posterior capsular rupture with vitreous loss and postoperative endophthalmitis were extracted from included studies. I2 statistics were used to assess heterogeneity across studies. Articles were systematically reviewed and a random effects meta-analysis model was applied to estimate the pooled effect size across studies. All statistical analyses were performed using Stata version 17.0 software. Sixteen studies, with a total of 3631 cataract-operated eyes, were included in the review. A total of 80.0% of all operated eyes had a preoperative VA of <3/60. At ≥4 weeks the percentage with good presenting VA ranged from 8% to 86%, with evidence of improved outcomes over time (95% confidence interval [CI] 45.0 to 67.0, I2=96.7%). With the best correction, 75% (95% CI 66.0 to 83.0, I2=98%) had a good outcome at ≥6 weeks postoperatively. The pooled prevalence of posterior capsular ruptures with vitreous loss was 4.0%, while 1.0% had postoperative endophthalmitis. In this review, the VA outcome after cataract surgery in Nigeria is well below the World Health Organization-recommended benchmark of >90% for a good result, with a higher rate of potentially blinding complications. The findings of this review suggest the need for improvement in modern surgical techniques, quality biometry and stocking of intraocular lenses of different powers and types to improve visual outcome and reduce complication rates.","PeriodicalId":49060,"journal":{"name":"International Health","volume":" ","pages":"693-704"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13530282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147515959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on: 'Impact of home-based follow-up care on hypertension control among patients attending Thika Level Five Hospital, Kiambu County, Kenya: a randomized controlled study'. 评论：“家庭随访护理对肯尼亚Kiambu县Thika五级医院患者高血压控制的影响：一项随机对照研究”。

IF 2.4 4区医学

International Health Pub Date : 2026-09-01 DOI: 10.1093/inthealth/ihag007

Benedict Kusi Ampofo, Marian Sapara Arthur, Solomon Gyabaah

引用次数: 0

Sex-disaggregated age-standardized crude suicide rates in Sierra Leone, 2000-2019. 2000-2019年塞拉利昂按性别分列的年龄标准化粗自杀率。

IF 2.4 4区医学

International Health Pub Date : 2026-09-01 DOI: 10.1093/inthealth/ihaf137

Umaru Sesay, Augustus Osborne

{"title":"Sex-disaggregated age-standardized crude suicide rates in Sierra Leone, 2000-2019.","authors":"Umaru Sesay, Augustus Osborne","doi":"10.1093/inthealth/ihaf137","DOIUrl":"10.1093/inthealth/ihaf137","url":null,"abstract":"Background: This study aims to determine the prevalence and sex-based disparities in age-standardized crude suicide rates in Sierra Leone from 2000 to 2019.Methods: This study employed a time-trend design utilizing nationally representative data on age-standardized crude suicide rates (per 100 000 population) from the WHO Health Equity Assessment Toolkit. The primary outcome measure was the age-standardized crude suicide rate, disaggregated by sex. Inequality measures, including difference, ratio, population attributable fraction and population attributable risk, were calculated to assess disparities between males and females.Results: From 2000 to 2019, the age-standardized crude suicide rate in Sierra Leone increased from 5.7 to 6.7 per 100 000 population, with notable fluctuations observed. Significant sex-based disparities were evident throughout the study period, with males consistently exhibiting higher suicide rates than females. The absolute difference in suicide rates between males and females narrowed slightly, from -4.0 per 100 000 in 2000 to -3.3 per 100 000 in 2019. However, the ratio of male-to-female suicide rates increased from 0.5 in 2000 to 0.6 in 2019.Conclusions: This study highlights persistent sex-based disparities in age-standardized crude suicide rates in Sierra Leone, disproportionately affecting males. This study recommends strengthening mental health services and integrating them into primary healthcare systems.","PeriodicalId":49060,"journal":{"name":"International Health","volume":" ","pages":"734-741"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13530285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145598047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coverage and determinants of hepatitis B virus vaccine uptake among children aged 12-36 months in Ethiopia: an analysis of the 2016 Ethiopian Demographic and Health Survey. 埃塞俄比亚12-36个月儿童乙型肝炎病毒疫苗接种的覆盖率和决定因素：2016年埃塞俄比亚人口与健康调查分析

IF 2.4 4区医学

International Health Pub Date : 2026-09-01 DOI: 10.1093/inthealth/ihaf142

Kathleen Kenyatta White, Tesfa Sewunet Alamneh, Josephine G Walker, Aaron G Lim

{"title":"Coverage and determinants of hepatitis B virus vaccine uptake among children aged 12-36 months in Ethiopia: an analysis of the 2016 Ethiopian Demographic and Health Survey.","authors":"Kathleen Kenyatta White, Tesfa Sewunet Alamneh, Josephine G Walker, Aaron G Lim","doi":"10.1093/inthealth/ihaf142","DOIUrl":"10.1093/inthealth/ihaf142","url":null,"abstract":"Background: In Ethiopia, chronic hepatitis B virus (HBV) prevalence is high (∼6%) and infant vaccination targets are unmet. We assessed HBV vaccination uptake and associations with parental sociodemographic and obstetric factors among children (aged 12-36 months) in Ethiopia.Methods: We utilised the 2016 Ethiopian Demographic and Health Survey. We included a weighted sample of 3,855 children (aged 12-36 month) to assess HBV vaccination coverage level (none, incomplete, and complete) and its spatial distribution. Additionally, we identified associated factors of HBV vaccination coverage level using ordinal logistic regression.Results: Overall, 51.2% of children received complete HBV vaccination, with wide regional variation. Older maternal age (adjusted odds ratio (AOR)=1.05, 95% confidence interval (CI): 1.02-1.07), better maternal education level (mean AOR=1.66-2.08), higher household wealth quantile (mean AOR=1.51-2.32), distance to a healthcare facility not a big problem (AOR=1.54, 95% CI: 1.25-1.89), and complete maternal continuum care utilisation (AOR=2.59, 95% CI: 1.25-5.30) were positively associated with HBV vaccination coverage, while higher number of children in the household (AOR=0.86, 95% CI: 0.79-0.92) was negatively associated.Conclusions: HBV vaccination coverage falls below World Health Organization (WHO) targets in Ethiopia and has substantial regional variation. Targeted vaccination campaigns for mothers in lower socioeconomic groups and larger families may improve vaccination coverage.","PeriodicalId":49060,"journal":{"name":"International Health","volume":" ","pages":"758-766"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13530290/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145745440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Translation and validation of the Igbo version of the Warwick-Edinburgh Mental Well-being Scale in Nigeria. 尼日利亚沃里克-爱丁堡心理健康量表伊博语版本的翻译与验证。

IF 2.4 4区医学

International Health Pub Date : 2026-09-01 DOI: 10.1093/inthealth/ihaf150

Ngozi Ekeke, Kingsley N Ukwaja, Amaka Onyima-Esmai, Edmund Ossai, Francis Chinawa, Joseph Chukwu, Charles Nwafor, Anthony Meka, Daniel Egbule, Precious Obioma-Henry, Martin Njoku, Chinwe Eze, Ngozi Murphy-Okpala

{"title":"Translation and validation of the Igbo version of the Warwick-Edinburgh Mental Well-being Scale in Nigeria.","authors":"Ngozi Ekeke, Kingsley N Ukwaja, Amaka Onyima-Esmai, Edmund Ossai, Francis Chinawa, Joseph Chukwu, Charles Nwafor, Anthony Meka, Daniel Egbule, Precious Obioma-Henry, Martin Njoku, Chinwe Eze, Ngozi Murphy-Okpala","doi":"10.1093/inthealth/ihaf150","DOIUrl":"10.1093/inthealth/ihaf150","url":null,"abstract":"There is growing international interest in the assessment of mental well-being. This study offers lessons learned from the field in the assessment of the validity and the reliability of the Igbo version of the Warwick-Edinburgh Mental Well-being Scale (Igbo-WEMWBS) among adult Igbos in areas affected by Hansen's disease in southern Nigeria. The World Health Organization methodologies were applied in translating the WEMWBS into Igbo. The psychometric properties and validity of the Igbo-WEMWBS were analysed. Of the 100 participants enrolled, 74.0% (n=74) were ≤40 y of age and 55.0% (n=55) were females. The total score of the new scale had a mean of 54.05 (95% confidence interval 52.31 to 55.79) and a range of 30-70. It was shown that a one-factor solution was optimal for the Igbo-WEMWBS. The Cronbach's α coefficient was 0.83 for the Igbo-WEMWBS. The stability of the Igbo-WEMWBS was found to be very high (r=0.96). There was a moderate correlation between the Igbo-WEMWBS and the World Health Organization-5 Well-Being Index and World Health Organization Disability Assessment Schedule. A cut-off score of ≤48.50 was found to be ideal for diagnosing very low mental well-being using the Igbo-WEMWBS. The Igbo-WEMWBS was found to be reliable and valid and can be used to assess mental well-being related to leprosy in the Igbo-speaking population of Nigeria.","PeriodicalId":49060,"journal":{"name":"International Health","volume":" ","pages":"685-688"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13530295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147730465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

'Comment on: Livestock farmers' knowledge, attitudes and practices relating to zoonoses in the Coastal Savannah zone of Ghana': reply. “评论：加纳沿海萨凡纳地区畜牧农民对人畜共患病的知识、态度和做法”：回复。

IF 2.4 4区医学

International Health Pub Date : 2026-09-01 DOI: 10.1093/inthealth/ihaf135

Sylvia Afriyie Squire, Godwin Yao Ameleke

引用次数: 0

Bayesian modeling of Escherichia coli contamination in household drinking water in Bangladesh: evidence from the Multiple Indicator Cluster Survey 2019. 孟加拉国家庭饮用水中大肠杆菌污染的贝叶斯模型：来自2019年多指标聚类调查的证据。

IF 2.4 4区医学

International Health Pub Date : 2026-09-01 DOI: 10.1093/inthealth/ihaf138

Iqramul Haq, Azizur Rahman, Mst Romana Akter, Delower Hossain, Diego Nobrega

{"title":"Bayesian modeling of Escherichia coli contamination in household drinking water in Bangladesh: evidence from the Multiple Indicator Cluster Survey 2019.","authors":"Iqramul Haq, Azizur Rahman, Mst Romana Akter, Delower Hossain, Diego Nobrega","doi":"10.1093/inthealth/ihaf138","DOIUrl":"10.1093/inthealth/ihaf138","url":null,"abstract":"Background: From a public health standpoint, there is merit in determining the levels of Escherichia coli in drinking water, but surveillance datasets often report censored values that may hinder traditional statistical analysis. This study aims to identify sociodemographic factors associated with the presence of E. coli in household drinking water in Bangladesh using Bayesian models for censored data, utilizing data from 6069 households in the Multiple Indicator Cluster Survey 2019.Methods: In terms of censoring, we considered two different Bayesian regression strategies: Bayesian Tobit Poisson regression and Bayesian Censored Generalized Poisson regression.Results: The Bayesian Censored Generalized Poisson regression model was identified as the optimal model for analyzing household fecal contamination. Regression analysis revealed significant associations between household E. coli levels and various factors including division, livestock ownership, location of water sources, treatment of drinking water, household head education, wealth index, source of drinking water, place of handwashing and toilet facility. Households using tube wells had lower E. coli levels than those using other sources. Furthermore, households using pit latrines had 1.03 times higher contamination levels than those using flush latrines.Conclusions: Levels of fecal contamination in household water in Bangladesh were alarming. Our findings underscore the need for targeted policy interventions in specific population segments to address household fecal contamination, highlighting the link between sociodemographic and environmental factors with E. coli levels in drinking water.","PeriodicalId":49060,"journal":{"name":"International Health","volume":" ","pages":"742-757"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13530297/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0