Leyda S Marrero Morales, Mustafa Ibrahim Al-Qaraghli, Kyle Polen, Msiba Selekwa, Tiffany Yeh, Kenechukwu Charles-Obi, Sang'udi Sang'udi, David Muhunzi, Elaine Liang, Nashivai Elias Kivuyo, Beatrice P Mushi, Ivy W Maina, Elia John Mmbaga, Katherine Van Loon, Mary Jue Xu, Cameron Eric Gaskill, Pendo M Ibrahim
{"title":"The current landscape and opportunities in gastrostomy care quality improvement in low- and middle-income countries: a scoping review.","authors":"Leyda S Marrero Morales, Mustafa Ibrahim Al-Qaraghli, Kyle Polen, Msiba Selekwa, Tiffany Yeh, Kenechukwu Charles-Obi, Sang'udi Sang'udi, David Muhunzi, Elaine Liang, Nashivai Elias Kivuyo, Beatrice P Mushi, Ivy W Maina, Elia John Mmbaga, Katherine Van Loon, Mary Jue Xu, Cameron Eric Gaskill, Pendo M Ibrahim","doi":"10.1093/inthealth/ihag045","DOIUrl":"https://doi.org/10.1093/inthealth/ihag045","url":null,"abstract":"<p><p>This scoping review examined gastrostomy tube use and care practices in low- and middle-income countries (LMICs) to identify complications, barriers and strategies to improve patient outcomes. Guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Extension for Scoping Reviews framework, six electronic databases were searched for studies published between 2000 and 2024. Of 1805 identified articles, 18 met the inclusion criteria and were classified into two themes: gastrostomy tube indications, techniques and outcomes; and care quality assessments and interventions. Patient outcome studies reported that adult complication rates ranged from 10% to 25%, with overall mortality from 0% to 48%, while paediatric complication rates ranged from 10% to 55%. Care quality studies identified gaps in nursing practices, protocol adherence and caregiver training. Interventions proposed included multidisciplinary care models and structured training programs for providers and caregivers. These findings highlight opportunities to improve gastrostomy outcomes in LMICs through establishing culturally sensitive and well-trained multidisciplinary care teams, implementing standardized protocols and caregiver engagement.</p>","PeriodicalId":49060,"journal":{"name":"International Health","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neglected tropical diseases in conflict zones: devastating consequences of a lack of inclusion.","authors":"Margriet den Boer, Koert Ritmeijer","doi":"10.1093/inthealth/ihaf165","DOIUrl":"https://doi.org/10.1093/inthealth/ihaf165","url":null,"abstract":"","PeriodicalId":49060,"journal":{"name":"International Health","volume":"18 3","pages":"313-315"},"PeriodicalIF":2.2,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jimmy Idraku, John Chol Ajack, Simran Budhwar, Mabeny Thiik, Sérgio Lopes, Sashi Leff, Yak Yak Bol, Xavier Badia-Rius
{"title":"Neglected tropical diseases elimination activities in South Sudan's largest refugee camp: lessons from 2 years of work.","authors":"Jimmy Idraku, John Chol Ajack, Simran Budhwar, Mabeny Thiik, Sérgio Lopes, Sashi Leff, Yak Yak Bol, Xavier Badia-Rius","doi":"10.1093/inthealth/ihaf156","DOIUrl":"https://doi.org/10.1093/inthealth/ihaf156","url":null,"abstract":"<p><p>Maban County, home to South Sudan's largest refugee camps, faces complex health and humanitarian challenges and is co-endemic for lymphatic filariasis and onchocerciasis. The division into two Implementation Units, one for the host community and the other one for the refugee camps, as recommended by the WHO Expanded Special Project for Elimination of Neglected Tropical Diseases (ESPEN), has improved the visibility of the refugee population, ensuring tailored planning and equitable inclusion in all stages of treatment delivery. Conducting mass drug administration campaigns in refugee camps requires strong coordination among multiple stakeholders and tailored training for frequently changing personnel, but benefits from the camps' structured layout, which enhances efficiency and cost-effectiveness. Morbidity management and disability prevention for lymphoedema and hydrocele were implemented for the first time in a refugee setting in South Sudan, highlighting the need for strong non-governmental organisation coordination and a national framework to standardise and reduce the cost of hydrocele surgery. Lessons from displacement-affected areas can guide inclusive strategies to ensure conflict-affected communities are not left behind in achieving WHO 2030 neglected tropical disease targets.</p>","PeriodicalId":49060,"journal":{"name":"International Health","volume":"18 3","pages":"320-323"},"PeriodicalIF":2.2,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angela McBride, Nguyen Van Hao, Phan Vinh Tho, Luong Thi Hue Tai, Nguyen Thanh Phong, Nguyen Thanh Ngoc, Nguyen Anh Huyen, Trinh Manh Hung, Martin J Llewelyn, Sophie Yacoub, Louise Thwaites, Hugo C Turner
{"title":"The cost of dengue shock and septic shock in Vietnam: a patient-centred economic analysis.","authors":"Angela McBride, Nguyen Van Hao, Phan Vinh Tho, Luong Thi Hue Tai, Nguyen Thanh Phong, Nguyen Thanh Ngoc, Nguyen Anh Huyen, Trinh Manh Hung, Martin J Llewelyn, Sophie Yacoub, Louise Thwaites, Hugo C Turner","doi":"10.1093/inthealth/ihaf105","DOIUrl":"10.1093/inthealth/ihaf105","url":null,"abstract":"<p><strong>Background: </strong>Dengue shock (DS) and septic shock (SS) are the most common infectious causes of shock in Vietnam. Little is known about the cost of an episode of DS or SS from the patient perspective. We aimed to describe the direct medical, non-medical and productivity costs associated with DS and SS.</p><p><strong>Methods: </strong>We recruited adults with DS and SS to a prospective observational study at the Hospital for Tropical Diseases, Ho Chi Minh City, from 2019 to 2021. We collected hospital bills, insurance status and out of pocket payments, and conducted an economic questionnaire at discharge, 1, 3 and 6 mo later. We calculated the proportion incurring catastrophic health expenditure (CHE) and catastrophic costs.</p><p><strong>Results: </strong>We recruited 127 adults with DS, of whom 118 survived, and 35 with SS, of whom 24 survived; 18.9% and 71.4% with DS and SS, respectively, incurred CHE. When non-medical and productivity costs were considered, the true cost of illness was 6.3 and 6.7 times higher than the hospital bill for DS and SS, respectively.</p><p><strong>Conclusions: </strong>Productivity costs must be counted when assessing the cost of critical illness in low- and lower-middle income countries. It is vital that financial protection systems are extended to cover patients requiring high-cost critical care in Vietnam.</p>","PeriodicalId":49060,"journal":{"name":"International Health","volume":" ","pages":"431-439"},"PeriodicalIF":2.2,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7618728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dawit Seyum Buda, Naomi Lorrain Nkoane, Thinavhuyo Robert Netangaheni
{"title":"Developing strategies to address persistent and recrudescent trachoma in Ethiopia using the Delphi techniques.","authors":"Dawit Seyum Buda, Naomi Lorrain Nkoane, Thinavhuyo Robert Netangaheni","doi":"10.1093/inthealth/ihaf155","DOIUrl":"10.1093/inthealth/ihaf155","url":null,"abstract":"<p><strong>Background: </strong>Despite significant progress, trachoma persistence and recrudescence in Ethiopia pose a challenge to global elimination of trachoma as a public health problem. Developing evidence-based, expert-informed strategies is crucial for achieving global elimination targets by 2030. Our aim was to develop strategies to address persistent and recrudescent trachoma using Delphi techniques.</p><p><strong>Methods: </strong>The study reviewed literature and studies from districts in southern Ethiopia where trachoma prevalence remains above the elimination threshold. A modified Delphi technique was employed to achieve consensus on strategies. Initially, 78 interventions were identified and reviewed by eight experts, resulting in 46 interventions and 6 strategies advancing to Delphi round 1. In round 1, 16 experts evaluated the strategies and interventions for relevance. In round 2, 32 experts from various institutions assessed them for relevance, feasibility and scalability. In round 3, 20 experts scored the final strategies and interventions for adoption or rejection. Data analysis was conducted using Microsoft Excel, with frequencies, percentages and summaries presented. Stability and descent analysis ensured the quality and consistency of the results.</p><p><strong>Results: </strong>Six strategies and 28 interventions were recommended, including enhancing service delivery, addressing workforce gaps, overcoming technological and supply chain barriers and ensuring robust data systems. Additionally, healthcare financing and enhanced leadership, management and stakeholder engagement were recommended.</p><p><strong>Conclusions: </strong>The study identified strategies and interventions to address trachoma persistence and recrudescence in Ethiopia, reinforcing efforts to strengthen the surgery, antibiotics, facial cleanliness and environmental improvement strategy.</p>","PeriodicalId":49060,"journal":{"name":"International Health","volume":" ","pages":"466-479"},"PeriodicalIF":2.2,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145901004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tegenu Balcha, Elias Yadeta, Abraham Negash, Magarsa Lami, Kasiye Shiferaw, Mekitie Wondafrash
{"title":"'I chose to keep it secret:' a qualitative study on the lived experience of women who underwent an abortion in Ethiopia.","authors":"Tegenu Balcha, Elias Yadeta, Abraham Negash, Magarsa Lami, Kasiye Shiferaw, Mekitie Wondafrash","doi":"10.1093/inthealth/ihaf146","DOIUrl":"10.1093/inthealth/ihaf146","url":null,"abstract":"<p><strong>Background: </strong>In Ethiopia, despite a decline in abortion-related mortality over the past decade, substantial challenges persist in ensuring universal safe abortion access. The lived experiences of women who underwent abortion are not well understood in Ethiopia. Thus, this study aimed to explore the lived experiences of women who underwent safe abortions in eastern Ethiopia.</p><p><strong>Methods: </strong>The study was conducted in Harari Region and Dire Dawa admiration using a descriptive phenomenological approach among 14 purposively selected women from Public health facilities. Data was collected through In-depth interviews using an interview guide. Verbatim transcription and translation of the recorded interviews were done. Finally, thematic analysis was conducted using Open Code 4.03 software.</p><p><strong>Results: </strong>Five major themes were emerged after analysis. Facilitators of abortion, Barriers to accessing safe abortion services, the need to keep abortion secret, religious perspectives, and Beliefs regarding the health impacts of abortion were the identified major themes.</p><p><strong>Conclusions: </strong>This study reveals that women seek abortion for various reasons and experience many challenges after abortion, but most of these reasons are not supported by Ethiopian's current abortion law. As a result, they encounter numerous obstacles when trying to obtain safe abortion services.</p>","PeriodicalId":49060,"journal":{"name":"International Health","volume":" ","pages":"490-498"},"PeriodicalIF":2.2,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145745428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katina Sommers, Wedsanley Jean Philippe, Gianni C Decastro, Merilien Jean-Baptiste, Farah-Nelhy Momprévil
{"title":"First ever programmatic implementation of triple drug therapy in the prevention of lymphatic filariasis in Haiti: lessons learned in improving the quality and coverage of locally led programming in lymphatic filariasis-persistent and conflict-affected endemic communes.","authors":"Katina Sommers, Wedsanley Jean Philippe, Gianni C Decastro, Merilien Jean-Baptiste, Farah-Nelhy Momprévil","doi":"10.1093/inthealth/ihag042","DOIUrl":"https://doi.org/10.1093/inthealth/ihag042","url":null,"abstract":"<p><p>Although significant strides have been made towards lymphatic filariasis (LF) elimination in Haiti, which has experienced ongoing multidimensional crises, 19 out of 140 communes still require mass drug administration (MDA) despite multiple rounds using the two-drug regimen of diethylcarbamazine (DEC) and albendazole. This includes the commune of Limonade, which has experienced persistently high LF prevalence despite nine rounds of two-drug MDAs since 2010. In September and October 2023 and July 2024, the Haitian Ministry of Public Health and Population, with support from IMA World Health and the US Centers for Disease Control and Prevention, adapted the standard WHO strategy, proving the feasibility, acceptability and scalability of LF MDA with three drugs (ivermectin, DEC and albendazole [IDA]) through the successful implementation of two rounds of IDA MDA in Limonade.</p>","PeriodicalId":49060,"journal":{"name":"International Health","volume":"18 3","pages":"316-319"},"PeriodicalIF":2.2,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emma M Harding-Esch, Francesca Bird, Ambreen Bashir, Louise A Kelly-Hope
{"title":"Challenges, barriers and opportunities for neglected tropical disease programs of conflict-affected African countries.","authors":"Emma M Harding-Esch, Francesca Bird, Ambreen Bashir, Louise A Kelly-Hope","doi":"10.1093/inthealth/ihaf149","DOIUrl":"https://doi.org/10.1093/inthealth/ihaf149","url":null,"abstract":"<p><strong>Background: </strong>Insecurity and conflict threaten achievement of global neglected tropical disease (NTD) targets. Identifying conflict-associated challenges and mitigation strategies can inform NTD programmatic decision-making.</p><p><strong>Methods: </strong>In-depth interviews were conducted with key stakeholders to explore their experiences of implementing NTD programs in conflict-affected regions in sub-Saharan Africa. Study 1 included a variety of stakeholders in Nigeria and study 2 included the NTD program managers from multiple countries. Thematic analysis was used to identify and extract key themes.</p><p><strong>Results: </strong>Fourteen participants (seven participants per study) from six countries and several NTD programs reported an array of complex challenges that were categorised into three common program-specific activity themes (implementation, community engagement, sustainability) and five common external influencing themes (access to areas; water, sanitation and hygiene; inclusivity; stakeholder partnering; financial resources). Study 1 included a unique theme for solutions. Several common subthemes (surveillance, community education, displaced populations, access for women) and unique study 1 subthemes were reported.</p><p><strong>Conclusions: </strong>Many complex interacting factors hinder NTD programs in conflict-affected NTD-endemic areas. The scale and breadth of the common and unique challenges and potential solutions require more investigation to enable the development of a practical framework to support programs in achieving the global NTD goals of 2030.</p>","PeriodicalId":49060,"journal":{"name":"International Health","volume":"18 3","pages":"340-351"},"PeriodicalIF":2.2,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fikre Hailekiros, Mebratu Mitiku, Merga Mekonnon, Tesfahun Bishaw, Adisu Abebe, Louise A Kelly-Hope
{"title":"Lessons from the field: adapting lymphatic filariasis morbidity mapping and patient care amidst conflict in Ethiopia.","authors":"Fikre Hailekiros, Mebratu Mitiku, Merga Mekonnon, Tesfahun Bishaw, Adisu Abebe, Louise A Kelly-Hope","doi":"10.1093/inthealth/ihag035","DOIUrl":"https://doi.org/10.1093/inthealth/ihag035","url":null,"abstract":"<p><p>Conflict in Ethiopia has prevailed in recent years and is impeding the implementation of lymphatic filariasis elimination activities for morbidity management and disability prevention. This led to the need for alternative approaches to ensure safe and effective implementation. Here, we outline the challenges that were faced (e.g., insecurity, restricted travel to external field teams, limited in-person training, direct patient care). First, we describe what potential solutions were discussed and decided. Second, we summarise the planned adapted strategy and how it was implemented through central-level planning, supervision, courier-based data transfer, and centralised data management. Third, we highlight what worked well, what did not, and key lessons learned. Finally, we outline areas for future consideration, including for example, the importance of global and national standard guidelines, and a better understanding of type and intensity of the conflict to help with realistic and safe planning.</p>","PeriodicalId":49060,"journal":{"name":"International Health","volume":"18 3","pages":"324-327"},"PeriodicalIF":2.2,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pneumonia in Ghana: prevalence, mortality and antimicrobial resistance-a systematic review and meta-analysis.","authors":"Frederick Kungu, Aaron Awere-Duodu, Eric S Donkor","doi":"10.1093/inthealth/ihaf077","DOIUrl":"10.1093/inthealth/ihaf077","url":null,"abstract":"<p><p>Pneumonia is a major cause of morbidity and mortality in Ghana, especially among children <5 y of age and the elderly. However, comprehensive data on its prevalence and distribution remain limited. This systematic review addresses this gap by analysing the prevalence, regional variations, risk factors, antimicrobial resistance and mortality rates of pneumonia in Ghana. We searched PubMed, ScienceDirect, Web of Science and African Journals Online databases, including 21 studies with a total of 124 582 participants. A random-effects meta-analysis estimated pooled prevalence and subgroup differences based on age, region and participant type. Heterogeneity was assessed using the I2 test and meta-regression, with sensitivity analysis also conducted. Study quality was evaluated using standardized Joana Briggs Institute checklists for prevalence studies. The pooled prevalence of pneumonia in Ghana was 22.01%, with significant regional variations. The highest prevalence was observed in a study conducted in the Greater Accra and Northern regions (32.31%), while the lowest was in the Upper West (4.83%). The prevalence in children <5 y of age was 17.79%. Hospitalized patients had a higher prevalence (22.14%) than community children (21.49%). Streptococcus pneumoniae was the most common pathogen, with high resistance (>70%) to co-trimoxazole, gentamicin and tetracycline. Key risk factors included indoor air pollution and seasonal changes. The mortality rate for pneumonia was found to be 3.07%. This systematic review highlighted significant regional disparities, pathogen resistance patterns and environmental risk factors that shape the burden of pneumonia in Ghana, providing critical evidence for targeted public health strategies. The findings highlight avenues for future research, including environmental drivers of transmission, focusing on underreported regions and surveillance of antibiotic resistance of pathogens isolated from pneumonia patients.</p>","PeriodicalId":49060,"journal":{"name":"International Health","volume":" ","pages":"369-380"},"PeriodicalIF":2.2,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145496661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}