{"title":"Características de imagen poco comunes de la osteomielitis multifocal recurrente crónica en adultos en PET/CT","authors":"R. Luo, W. Zhang, A. Kuang, Y. Li","doi":"10.1016/j.remn.2025.500121","DOIUrl":"10.1016/j.remn.2025.500121","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 3","pages":"Article 500121"},"PeriodicalIF":1.6,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143868720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Kara Gedik , A. Volkan Çelik , M.U. Yalçın , M. Koplay , F. Yılmaz , H. Önner
{"title":"Comparación de los rendimientos diagnósticos de la gammagrafía de perfusión miocárdica SPECT corregida por atenuación por TC y corregida sin atenuación en la enfermedad de las arterias coronarias","authors":"G. Kara Gedik , A. Volkan Çelik , M.U. Yalçın , M. Koplay , F. Yılmaz , H. Önner","doi":"10.1016/j.remn.2024.500085","DOIUrl":"10.1016/j.remn.2024.500085","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Tissue attenuation reduces the specificity of the myocardial perfusion imaging single photon emission tomography (SPECT), which leads reduced diagnostic accuracy. The aim of this study is to compare performances of non-attenuation corrected (NAC), computed tomography based-attenuation corrected (AC) and prone images for qualitative and semi-quantitative analysis of myocardial perfusion SPECT in diagnosis of coronary artery disease (CAD).</div></div><div><h3>Materials and methods</h3><div>Eighty six patients in whom NAC, AC and prone images were obtained with SPECT, and whose coronary angiography/CT coronary angiography was completed within 3 months, were retrospectively studied. Myocardial perfusion scintigraphy was performed using SPECT/CT dual-headed gamma camera. Images were evaluated qualitatively and semi-quantitatively using 20-segment model. Analyzes of global myocardium and LAD, RCA, Cx vascular areas as regional analysis were performed. In qualitative evaluation, if SPECT study was abnormal, relevant coronary artery area was recorded. Quantitative Perfusion SPECT (QPS) program was used in semi-quantitative analysis; Summed Stress Score (SSS)<!--> <!-->≥<!--> <!-->4 was accepted for presence of CAD in per-patient analysis. In regional analysis SSS<!--> <!-->≥<!--> <!-->2 was taken into account. Coronary angiography/CT coronary angiography was used as gold standard. Threshold value was determined as ≥<!--> <!-->50% and above luminal diameter narrowing. While AC and NAC methods were compared for per-patient analysis and each vascular area; 3<!--> <!-->imaging methods including prone acquisition, were compared for the RCA area. Diagnostic performances of the methods were evaluated by comparing the areas under the curve with ROC analysis.</div></div><div><h3>Results</h3><div>In visual evaluation, sensitivity of AC was significantly lower than NAC in analyzes of per-patient, RCA and Cx areas (global 76.92% vs 86.15%, RCA 60.87% vs 82.61%, Cx 58.97% vs 69.23%, respectively; <em>P</em> <!--><<!--> <!-->.05). Sensitivity of prone imaging was significantly higher than AC in analysis of the RCA area (76.09% vs 60.87%, respectively; <em>P</em> <!--><<!--> <!-->.05) Specificity values were higher in analyzes of global, RCA and Cx areas in AC than in NAC method; this difference was significant in RCA and Cx areas (RCA 70% vs 42.50%, Cx 85.11% vs 70.21%, respectively; <em>P</em> <!--><<!--> <!-->.05). In semi-quantitative evaluation, AC and NAC had similar sensitivity and specificity in global and regional analyzes; in RCA area, no significant difference was detected between the 3<!--> <!-->methods. In ROC analysis, no significant difference was detected between methods in per-patient and regional analyzes both in visual and semi-quantitative evaluation.</div></div><div><h3>Conclusions</h3><div>CT-based attenuation correction increases specificity, but reduces sensitivity in the diagnosis of CAD in","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 3","pages":"Article 500085"},"PeriodicalIF":1.6,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143868615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Malhotra , A. Peix , C. Gutierrez-Villamil , M. Bazan , R. Giubbini , C. Cueva , E. Estrada , D. Paez
{"title":"Aplicación práctica de la imagen multimodal en la cardio-oncología en América Latina","authors":"S. Malhotra , A. Peix , C. Gutierrez-Villamil , M. Bazan , R. Giubbini , C. Cueva , E. Estrada , D. Paez","doi":"10.1016/j.remn.2024.500086","DOIUrl":"10.1016/j.remn.2024.500086","url":null,"abstract":"<div><div>Latin America is one of the regions in the world with the highest levels of overweight, dyslipidemia, and diabetes mellitus, which, together with smoking and high blood pressure, are common risk factors for cardiovascular and oncological diseases. Chemotherapy (CT) and radiotherapy (RT) have become two of the mainstays of treatment for several types of cancer. One of the most worrisome side effects generated by CT and RT is cardiotoxicity. There are several imaging techniques in cardiology that can inform the presence of underlying disease, but they differ in their availability and access to the masses, their accuracy and repeatability, all of which are important determinants of the applicability of these techniques in routine clinical practice. Thus, it is mandatory to promote a clinically effective and a cost-effective multimodality approach for risk stratification, diagnosis and management of cardiovascular diseases in oncologic patients. The purpose of this review is to inform cardiologists, oncologists, cardio-oncologists and imaging cardiologists on the cardiac imaging modalities that can be applied in patients with cancer, the differences among imaging techniques and recommendations on how to apply them in Latin America.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 3","pages":"Article 500086"},"PeriodicalIF":1.6,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Bota-Bota, M. Pombo-López, I. Martínez-Rodríguez, F. Gómez-de la Fuente, J. Jiménez-Bonilla, R. Quirce
{"title":"Metástasis única de melanoma maligno cutáneo en la vesícula biliar detectada con 18F-FDG PET/TC","authors":"A. Bota-Bota, M. Pombo-López, I. Martínez-Rodríguez, F. Gómez-de la Fuente, J. Jiménez-Bonilla, R. Quirce","doi":"10.1016/j.remn.2025.500120","DOIUrl":"10.1016/j.remn.2025.500120","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 3","pages":"Article 500120"},"PeriodicalIF":1.6,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143868719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.J. Rosales , M.L. Domínguez , L. Sancho , E. Prieto , M. de Arcocha , I. Torres , A. Roteta , R. Ramos , G. Quincoces , en nombre del Grupo de Oncología de la SEMNIM
{"title":"Estado del arte y perspectivas futuras de nuevos radionúclidos en Medicina Nuclear. Parte I","authors":"J.J. Rosales , M.L. Domínguez , L. Sancho , E. Prieto , M. de Arcocha , I. Torres , A. Roteta , R. Ramos , G. Quincoces , en nombre del Grupo de Oncología de la SEMNIM","doi":"10.1016/j.remn.2024.500082","DOIUrl":"10.1016/j.remn.2024.500082","url":null,"abstract":"<div><div>This continuing education analyzes recent advances in Nuclear Medicine focused on the development of new radiopharmaceuticals that improve both the diagnosis and treatment of complex diseases. The focus is on teragnosis, which combines diagnosis and treatment by means of pairs of radiopharmaceuticals directed to the same molecular target, which allows the personalization of treatments.</div><div>This first part specifically reviews the teragnostic pairs copper-64/copper-67, lead-212/lead-203 and scandium-44/scandium-47, highlighting their physical characteristics, methods of production and potential clinical applications.</div><div>Despite the challenges in their production, their versatility and effectiveness are driving their clinical application in oncology and other diseases. The text also addresses the development of new radiopharmaceuticals and their impact on precision medicine, pointing out future directions and opportunities for research in this field.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500082"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143096747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluación de la fiabilidad y legibilidad de las respuestas de los chatbots como recurso de información al paciente para las exploraciones PET-TC más comunes","authors":"N. Aydinbelge-Dizdar , K. Dizdar","doi":"10.1016/j.remn.2024.500065","DOIUrl":"10.1016/j.remn.2024.500065","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to evaluate the reliability and readability of responses generated by two popular AI-chatbots, ‘ChatGPT-4.0’ and ‘Google Gemini’, to potential patient questions about PET/CT scans.</div></div><div><h3>Materials and methods</h3><div>Thirty potential questions for each of [<sup>18</sup>F]FDG and [<sup>68</sup>Ga]Ga-DOTA-SSTR PET/CT, and twenty-nine potential questions for [<sup>68</sup>Ga]Ga-PSMA PET/CT were asked separately to ChatGPT-4 and Gemini in May 2024. The responses were evaluated for reliability and readability using the modified DISCERN (mDISCERN) scale, Flesch Reading Ease (FRE), Gunning Fog Index (GFI), and Flesch-Kincaid Reading Grade Level (FKRGL). The inter-rater reliability of mDISCERN scores provided by three raters (ChatGPT-4, Gemini, and a nuclear medicine physician) for the responses was assessed.</div></div><div><h3>Results</h3><div>The median [min-max] mDISCERN scores reviewed by the physician for responses about FDG, PSMA and DOTA PET/CT scans were 3.5 [2-4], 3 [3-4], 3 [3-4] for ChatGPT-4 and 4 [2-5], 4 [2-5], 3.5 [3-5] for Gemini, respectively. The mDISCERN scores assessed using ChatGPT-4 for answers about FDG, PSMA, and DOTA-SSTR PET/CT scans were 3.5 [3-5], 3 [3-4], 3 [2-3] for ChatGPT-4, and 4 [3-5], 4 [3-5], 4 [3-5] for Gemini, respectively. The mDISCERN scores evaluated using Gemini for responses FDG, PSMA, and DOTA-SSTR PET/CTs were 3 [2-4], 2 [2-4], 3 [2-4] for ChatGPT-4, and 3 [2-5], 3 [1-5], 3 [2-5] for Gemini, respectively. The inter-rater reliability correlation coefficient of mDISCERN scores for ChatGPT-4 responses about FDG, PSMA, and DOTA-SSTR PET/CT scans were 0.629 (95% CI= 0,32-0,812), 0.707 (95% CI<!--> <!-->=<!--> <!-->0.458-0.853) and 0.738 (95% CI<!--> <!-->=<!--> <!-->0.519-0.866), respectively (p<<!--> <!-->0.001). The correlation coefficient of mDISCERN scores for Gemini responses about FDG, PSMA, and DOTA-SSTR PET/CT scans were 0.824 (95% CI<!--> <!-->=<!--> <!-->0.677-0.910), 0.881 (95% CI<!--> <!-->=<!--> <!-->0.78-0.94) and 0.847 (95% CI<!--> <!-->=<!--> <!-->0.719-0.922), respectively (p<<!--> <!-->0.001). The mDISCERN scores assessed by ChatGPT-4, Gemini, and the physician showed that the chatbots’ responses about all PET/CT scans had moderate to good statistical agreement according to the inter-rater reliability correlation coefficient (p<<!--> <!-->0,001). There was a statistically significant difference in all readability scores (FKRGL, GFI, and FRE) of ChatGPT-4 and Gemini responses about PET/CT scans (p<<!--> <!-->0,001). Gemini responses were shorter and had better readability scores than ChatGPT-4 responses.</div></div><div><h3>Conclusion</h3><div>There was an acceptable level of agreement between raters for the mDISCERN score, indicating agreement with the overall reliability of the responses. However, the information provided by AI-chatbots cannot be easily read by the public.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500065"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143096585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R.M. Angulo Amorese, F.J. Pena Pardo, J.C. Rodríguez Gómez, N. Disotuar Ruiz, M.P. Talavera Rubio, V.M. Poblete García
{"title":"Metástasis ganglionares mediastínicas de cáncer de próstata: mayor precisión diagnóstica de la PET/TC con 18F-DCFPyL frente a la 18F-colina","authors":"R.M. Angulo Amorese, F.J. Pena Pardo, J.C. Rodríguez Gómez, N. Disotuar Ruiz, M.P. Talavera Rubio, V.M. Poblete García","doi":"10.1016/j.remn.2024.500063","DOIUrl":"10.1016/j.remn.2024.500063","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500063"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Simó , O. Persiva , L. Sánchez , J.B. Montoro , I. Sansano , A. Vázquez , F. Ascanio , C. Alemán
{"title":"Asociación de los hallazgos de la PET-TC y la VATS con la histología pleural en el estudio del derrame pleural","authors":"M. Simó , O. Persiva , L. Sánchez , J.B. Montoro , I. Sansano , A. Vázquez , F. Ascanio , C. Alemán","doi":"10.1016/j.remn.2024.500059","DOIUrl":"10.1016/j.remn.2024.500059","url":null,"abstract":"<div><h3>Introduction</h3><div>Histological analysis of the pleura obtained by video-assisted thoracoscopic surgery (VATS) is the best diagnostic technique in the study of neoplastic pleural effusions. This study evaluates the relationship between positron emission tomography (PET)/computed tomography (CT) and VATS findings, the result of the first pleural biopsy, and the final diagnosis of malignancy or non-malignancy.</div></div><div><h3>Methods</h3><div>Prospective study of consecutive patients with pleural effusions undergoing PET/CT and VATS from October 2013 to December 2023. The following variables were recorded: PET/CT score (nodular pleural thickening, pleural nodules with standardized uptake value (SUV) ><!--> <!-->7.5, lung mass or extra pleural malignancy, mammary lymph node with SUV ><!--> <!-->4.5 and cardiomegaly); VATS data (drained volume, visceral and parietal pleural thickening, nodules or masses, septa, plaques, fluid appearance, trapped lung, and suspected diagnosis of the procedure), as well as the histological study of the first pleural biopsy (benign or malignant) and the final diagnosis of benign or malignant pleural effusion. A logistic regression study of the variables was performed.</div></div><div><h3>Results</h3><div>95.8% of the patients with PET/CT and pleuroscopy not suggestive of malignancy had non-malignant histological findings, while 93.2% of the patients with PET/CT and pleuroscopy suggestive of malignancy had malignant histological findings. PET/CT, pleuroscopy, and the result of the first pleural biopsy showed a significant association with the final diagnosis of pleural effusion.</div></div><div><h3>Conclusions</h3><div>There is a strong association between PET/CT findings, VATS and pleural histology.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500059"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143096586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}