Revista Espanola De Medicina Nuclear E Imagen Molecular最新文献

{"title":"Gestión de riesgo del tratamiento con radioyodo en el cáncer diferenciado de tiroides","authors":"J. Villena-Salinas ,&nbsp;M.A. Sempere Alcocer ,&nbsp;M. Gallego Peinado","doi":"10.1016/j.remn.2024.500029","DOIUrl":"10.1016/j.remn.2024.500029","url":null,"abstract":"<div><h3>Introduction</h3><p>Patient safety is paramount in providing quality healthcare and constitutes a global concern for healthcare systems. Radioiodine treatment to patients with well-differentiated thyroid cancer is not without risks. The aim of this study is to identify, evaluate and mitigate the risks associated with this procedure.</p></div><div><h3>Materials and methods</h3><p>A single-centre descriptive study was conducted in which risk management was carried out by establishing a risk map using FMEA methodology.</p></div><div><h3>Results</h3><p>Based on the process map 6 sub-processes and 23 failure modes in the three phases of the treatment process were analysed. According to risk priority number (RPN), the sub-process with the highest risk was administrative management (RPN 82), followed by treatment per se and post-treatment imaging (both with RPN 70). An overall process RPN of 300 (156 pre-treatment, 74 treatment and 70 post-treatment) was obtained. Failures directly related to the patient pose a high risk. The implementation of verification systems, performing tasks earlier and providing quality medical information are the most relevant preventive measures to be implemented.</p></div><div><h3>Conclusions</h3><p>The application of the FMEA methodology in the risk management for radioiodine treatment is a valuable tool for improving the quality and safety of this process. The risk map has been able to identify failures at different stages, assess their causes and effects, prioritise the risks identified and implement preventive and corrective measures that can be monitored, ensuring the effectiveness of the actions taken.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 4","pages":"Article 500029"},"PeriodicalIF":1.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141847010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meningioma nasosinusal recurrente: perspectivas de la imagen con receptores de somatostatina","authors":"A.S. Abdlkadir ,&nbsp;R. Amarin ,&nbsp;E. Estrada-Lobato ,&nbsp;A. Al-Ibraheem","doi":"10.1016/j.remn.2024.500014","DOIUrl":"10.1016/j.remn.2024.500014","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 4","pages":"Article 500014"},"PeriodicalIF":1.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ablación percutánea guiada por ecografía de nódulos tiroideos con [177Lu]Lu-MAA (LUTMA): estudio de viabilidad","authors":"S. Sager ,&nbsp;E. Akgun ,&nbsp;M. Abuqbeitah ,&nbsp;A. Nazari ,&nbsp;N. Yeyin ,&nbsp;E. Karayel ,&nbsp;H. Pehlivanoglu ,&nbsp;A. Aygun ,&nbsp;H. Burcak Sayman","doi":"10.1016/j.remn.2024.500023","DOIUrl":"10.1016/j.remn.2024.500023","url":null,"abstract":"<div><h3>Purpose</h3><p>The main purpose is to evaluate the safety, and efficacy of ¹⁷⁷Lutetium labeled macroaggregated albumin (LUTMA) ablation of thyroid nodules.</p></div><div><h3>Material and methods</h3><p>Patients with confirmed benign nodules who were not candidate or did not accept surgery were enrolled. Under ultrasonography (USG) guidance, LUTMA which was produced in our department, was administered into the nodules. Nodule volumes were assessed via USG before the injection and at 1-week, 1-month, and 3-months post-treatment. We calculated the volume reduction rates (VRRs) for these intervals. To detect extranodular activity leakage, patients underwent SPECT/CT imaging at one hour, 24<!--> <!-->hours, and one week post-injection.</p></div><div><h3>Results</h3><p>Fifteen patients (male: 12, female: 3) with benign thyroid nodules were eligible to join this study. These nodules were categorized as cystic (n<!--> <!-->=<!--> <!-->9), solid (n<!--> <!-->=<!--> <!-->3), or mixed (n<!--> <!-->=<!--> <!-->3). Median nodules volume was 6.59<!--> <!-->ml (range: 0.56-55<!--> <!-->ml). Predicted absorbed dosee to the nodules varied between 10 to 1036<!--> <!-->Gy. The VRRs at 3. months was 85% for all nodule types with gradual increases over time: 0-92%, 20-97%, and 28-98% at 1. week, 1. month, and 3-months, respectively. The median VRR of cystic nodules was 89% (range: 81%-98%) at 3-months. It is significantly higher than solid ones (p<!--> <!-->=<!--> <!-->0.009). None of the patients experienced adverse reactions or discomfort during the injection or follow-up.</p></div><div><h3>Conclusion</h3><p>LUTMA treatment significantly reduces the volume of benign thyroid nodules, offering relief from disease-associated symptoms and cosmetic concerns. It emerges as a promising alternative to surgical and other local treatments for benign thyroid nodule ablation.</p></div><div><h3>Clinical signification</h3><p>LUTMA is a novel theranostic radiopharmaceutical which is promising in local ablative treatment of benign thyroid nodules.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 4","pages":"Article 500023"},"PeriodicalIF":1.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141702469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rabdomiosarcoma prostático en un paciente de seis años evaluado mediante [18F]FDG PET/TC","authors":"","doi":"10.1016/j.remn.2024.500016","DOIUrl":"10.1016/j.remn.2024.500016","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 4","pages":"Article 500016"},"PeriodicalIF":1.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141415622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Características de la imagen de un angiolipoma espinal atípico en PET/TC y resonancia magnética (RM)","authors":"Y. Li ,&nbsp;R. Luo ,&nbsp;W. Zhang,&nbsp;L. Li","doi":"10.1016/j.remn.2024.500015","DOIUrl":"10.1016/j.remn.2024.500015","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 4","pages":"Article 500015"},"PeriodicalIF":1.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilidad de la gammagrafía ósea como reflejo del estado nutritivo del paciente, un caso de escorbuto","authors":"J.A. Vázquez Gómez ,&nbsp;M. Salvá Arteaga ,&nbsp;I. Roncero Sánchez-Cano ,&nbsp;A. Fernández Marín ,&nbsp;M.P. Garrastachu Zumarán ,&nbsp;M.Y. Ruiz del Prado","doi":"10.1016/j.remn.2024.500012","DOIUrl":"https://doi.org/10.1016/j.remn.2024.500012","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 3","pages":"Article 500012"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141072504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluación de la heterogeneidad molecular en tumores neuroendocrinos mediante PET/TC con [68Ga]Ga-DOTA-TOC y [18F]FDG","authors":"Z. Nogareda Seoane ,&nbsp;M.C. Mallón Araújo ,&nbsp;A. Calatayud Cubes ,&nbsp;C. Barberán Corral ,&nbsp;Y. Domínguez Novoa ,&nbsp;A. Cousillas Castiñeira ,&nbsp;N. Martínez Lago ,&nbsp;J.M. de Matías Leralta ,&nbsp;V. Pubul Nuñez","doi":"10.1016/j.remn.2024.500011","DOIUrl":"https://doi.org/10.1016/j.remn.2024.500011","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of the study was evaluate the diagnostic performance of [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG PET/CT in patients with histologically proven neuroendocrine tumors (NETs), as well as the correlation of the visualized findings with the tumor grade.</p></div><div><h3>Material and methods</h3><p>We included 50 patients with NETs who underwent both [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG PET/TC. The pooled sensitivity of both scans was compared, as well as [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG for each tumor grade (grade<!--> <!-->1 [G1], grade<!--> <!-->2 [G2] and grade<!--> <!-->3 [G3]). Also, the sensitivity of [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG as a function of the continuous variable Ki-67 was investigated. Finally, the number of lesions detected by both PET radiopharmaceuticals for each tumor grade was compared.</p></div><div><h3>Results</h3><p>The pooled sensitivity of both PET/CT (96%) was higher than [⁶⁸Ga]Ga-DOTA-TOC (84%) and [¹⁸F]FDG (44%) separately, with statistically significant differences. The sensitivity of [⁶⁸Ga]Ga-DOTA-TOC was higher than [¹⁸F]FDG in both G1 (<em>P</em> <!-->=<!--> <!-->.004) and G2 (<em>P</em> <!-->&lt;<!--> <!-->.001). In G3 the performance of both scans detected disease in 100% of this subgroup. The sensitivity of [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG PET/CT correlated significantly with the Ki-67 proliferative index. In G2 patients the number of lesions detected with [⁶⁸Ga]Ga-DOTA-TOC was higher than [¹⁸F]FDG.</p></div><div><h3>Conclusions</h3><p>The performance of both PET/CT, particularly in G2 and G3, demonstrates the molecular heterogeneity of metastatic NETs and contributes to the selection of a more appropriate treatment, particularly in those high-grade patients who may benefit from radionuclide therapy (PRRT).</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 3","pages":"Article 500011"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141073174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detección de salpingitis mediante PET con 18F-FDG en paciente que presenta síndrome febril de origen desconocido","authors":"J.R. Garcia,&nbsp;A. Compte,&nbsp;L. Mont,&nbsp;S. Mourelo,&nbsp;P. Bassa,&nbsp;E. Riera","doi":"10.1016/j.remn.2024.500010","DOIUrl":"10.1016/j.remn.2024.500010","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 3","pages":"Article 500010"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141026485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Análisis radiómico PET intra y peritumoral para predecir la respuesta patológica en pacientes con cáncer de mama que reciben quimioterapia neoadyuvante","authors":"A. Aksu ,&nbsp;Z.G. Güç ,&nbsp;K.A. Küçüker ,&nbsp;A. Alacacıoğlu ,&nbsp;B. Turgut","doi":"10.1016/j.remn.2024.500002","DOIUrl":"https://doi.org/10.1016/j.remn.2024.500002","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of our study was to evaluate the contribution of ¹⁸Fluorine-fluorodeoxyglucose positron emission tomography (18F-FDG PET) radiomic data obtained from both the tumoral and peritumoral area in predicting pathological complete response (pCR) in patients with locally advanced breast cancer receiving neoadjuvant chemotherapy (NAC).</p></div><div><h3>Methods</h3><p>Female patients with a diagnosis of invasive ductal carcinoma who received NAC were evaluated retrospectively. The volume of interest (VOI) of the primary tumor (VOI-_T) was manually segmented, then a voxel-thick VOI was added around VOI-_T to define the peritumoral area (VOI-_PT). Morphological, intensity-based, histogram and texture parameters were obtained from VOIs. The patients were divided into two groups as pCR and non-complete pathological response (npCR). A «radiomic model» was created with only radiomic features, and a «patho-radiomic model» was created using radiomic features and immunohistochemical data.</p></div><div><h3>Results</h3><p>Of the 66 patients included in the study, 21 were in the pCR group. The only statistically significant feature from the primary tumor among patients with pCR and npCR was Morphological_Compacity-_T (AUC: 0.666). Between response groups, a significant difference was detected in 2 morphological, 1 intensity, 4 texture features from VOI-_PT; no correlation was found between Morphological_Compacity-_PT and NGLDM_contrast-_PT. The obtained radiomic model's sensitivity and accuracy values were calculated as 61.9% and 75.8%, respectively (AUC: 0.786). When HER2 status was added, sensitivity and accuracy values of the patho-radiomic model increased to 85.7% and 81.8%, respectively (AUC: 0.903).</p></div><div><h3>Conclusions</h3><p>Evaluation of PET peritumoral radiomic features together with the primary tumor, rather than just the primary tumor, provides a better prediction of the pCR to NAC in patients with breast cancer.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 3","pages":"Article 500002"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141073161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Valor diagnóstico de la imagen PET/TC con [68Ga]Ga-FAPI en el tumor de células redondas pequeñas desmoplásticas","authors":"Y. Liu ,&nbsp;H. Liu ,&nbsp;Z. Wan ,&nbsp;Y. Chen ,&nbsp;J. Zhang","doi":"10.1016/j.remn.2024.500013","DOIUrl":"10.1016/j.remn.2024.500013","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 3","pages":"Article 500013"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2253654X24000209/pdfft?md5=3c33e724fb5728ac25df5b275aad77fd&pid=1-s2.0-S2253654X24000209-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141056832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}