Revista Espanola De Medicina Nuclear E Imagen Molecular最新文献

{"title":"Enfermedad por micropartículas en prótesis de cadera, a propósito de un caso","authors":"J.L. Díaz Moreno, I.E. Sánchez-Rodríguez, B. Hervás-Sanz, P. Notta-González, C. Martínez-Ramos, L. Gràcia-Sánchez","doi":"10.1016/j.remn.2024.500078","DOIUrl":"10.1016/j.remn.2024.500078","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 2","pages":"Article 500078"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilidad de la PET/TC con [18F]F-fluorocolina en la valoración de respuesta a la terapia antiandrogénica en pacientes con cáncer de próstata","authors":"K. Quintero ,&nbsp;E. Vila ,&nbsp;L. Ferrer-Mileo ,&nbsp;D. Vas ,&nbsp;Maria J. Ribal ,&nbsp;M. Garcia-Herreros ,&nbsp;N. Navarro ,&nbsp;M. Tormo-Ratera ,&nbsp;C. Aversa ,&nbsp;A. Vilaseca ,&nbsp;A. Farré-Melero ,&nbsp;D. Fuster ,&nbsp;P. Paredes ,&nbsp;grupo de Medicina Nuclear Clínic Barcelona (MNCB)","doi":"10.1016/j.remn.2024.500083","DOIUrl":"10.1016/j.remn.2024.500083","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the correlation between response assessment measured by PET/CT with [¹⁸F] F-fluorocholine (Choline PET/CT) and serum levels of PSA in patients with prostate cancer under antiandrogenic treatment.</div></div><div><h3>Methodology</h3><div>A retrospective study included patients with CRPC and CSPC treated with enzalutamide, abiraterone, or apalutamide between June 2018 and July 2021, who underwent baseline and a follow-up Choline PET/CT. The difference in maximum SUVmax (ΔSUV) between both studies and the PSA value before and at follow-up were recorded. The response to treatment was compared by PSA vs. PET, assessing their association, agreement, and correlation.</div></div><div><h3>Results</h3><div>Thirty patients were included (median age 74 years, range 68-78), 12 with CSPC and 18 with CRPC; 22 had nodal disease, and 15 had active bone disease. The average time between pre-treatment and follow-up PET/CT was 11 months (range 3.5-23).</div><div>Patients with extra-nodal metastatic disease at the beginning of treatment showed a higher correlation between PSA and ΔSUV (OR 4.375). In patients with bone disease at the start of treatment, 80% were classified as non-responders on PET response assessment, while only 40% were non-responders by PSA.</div><div>The correlation between PET and PSA was mild <em>(Kendall's tau_b</em> 0.26), and the classification into Responders/Non-responders had only slight agreement (<em>Cohen's kappa</em> 0.30).</div></div><div><h3>Conclusion</h3><div>Choline PET/CT shows low concordance with the PSA values obtained during the follow-up of response to anti-androgen therapy, especially in patients with bone involvement.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 2","pages":"Article 500083"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143510917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Papel y aplicaciones de la [18F]FDG PET/TC en la evaluación de la infección e inflamación osteoarticular. Parte II","authors":"E. Noriega-Álvarez ,&nbsp;B. Rodríguez Alfonso ,&nbsp;J.J. Rosales Castillo ,&nbsp;A. Moreno Ballesteros ,&nbsp;E. López Rodríguez ,&nbsp;S. Sanz Viedma ,&nbsp;M.P. Orduña Diez ,&nbsp;L. Domínguez Gadea","doi":"10.1016/j.remn.2024.500102","DOIUrl":"10.1016/j.remn.2024.500102","url":null,"abstract":"<div><div>[¹⁸F]FDG PET/TC is an emerging tool in the evaluation of inflammatory arthropathies, characterised by their insidious course and clinical overlap. It allows detection of subclinical inflammation, assessment of systemic involvement and quantification of metabolic parameters useful in early diagnosis and therapeutic monitoring. In rheumatoid arthritis, it correlates with clinical indices (<em>Disease Activity Score</em>), serological markers (CRP, anti-citrullinated protein antibodies) and ultrasound findings, and facilitates the identification of complications such as cardiovascular and pulmonary involvement. In spondyloarthritis, its ability to identify enthesitis and peripheral synovitis is promising, although less studied. In addition, [¹⁸F]FDG PET/TC evaluates the response to biological treatments, helping to optimise therapeutic decisions. However, its implementation faces challenges such as lack of standardised indications, incidental findings and technical artefacts. Although not routinely recommended, its usefulness in specific settings underlines the need for further studies to consolidate its role in the management of these diseases. In this manuscript, we present a brief review providing general and practical information about the role of [¹⁸F]FDG PET/TC in inflammatory osteoarticular pathology, while “Role and applications of [¹⁸F]FDG PET/CT in the assessment of osteoarticular infection and inflammation - Part I” has addressed its role in infectious osteoarticular disease.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 2","pages":"Article 500102"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143510911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Valor clínico de un PET/TC con [18F]F-PSMA negativo en pacientes diagnosticados de cáncer de próstata tratados con prostatectomía con elevación del PSA, inferior a 1 ng/ml, en los resultados de la radioterapia de rescate","authors":"M. Cózar Santiago ,&nbsp;J. García Garzón ,&nbsp;A. Esteban Hurtado ,&nbsp;J. Pastor Peiro ,&nbsp;J. Ferrer Rebolleda","doi":"10.1016/j.remn.2024.500071","DOIUrl":"10.1016/j.remn.2024.500071","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the clinical value of [¹⁸F]F-PSMA negative PET/CT, in patients diagnosed with prostate cancer treated with prostatectomy with elevated PSA less than 1<!--> <!-->ng/mL, on the outcome of salvage radiotherapy.</div></div><div><h3>Method</h3><div>We prospectively included 98 patients diagnosed with prostate cancer treated with prostatectomy with biochemical recurrence [mean PSA 0.51<!--> <!-->ng/mL (range 0.17-1,0<!--> <!-->ng/mL)] who were referred for an [¹⁸F]F-PSMA-PET/CT study.</div><div>The [¹⁸F]F-PSMA-PET/CT scan was negative in 53/98 patients (54.09%). Differences were analysed between those patients who were or were not candidates for pelvic salvage radiotherapy (PSRT) decided upon multidisciplinary committee and patient consent, with a minimum follow-up time for 1<!--> <!-->year. Response to treatment was defined as a 50% reduction in PSA levels. Recurrence was ascertained upon clinical, analytical and imaging follow-up outcomes.</div></div><div><h3>Results</h3><div>54.7% (29/53) of the patients with a negative [¹⁸F]F-PSMA-PET/CT underwent PSRT. Of these, 93.1% (27/29) patients demonstrated response to treatment (PSMA false negatives). The remaining two patients showed fluctuating PSA levels without detecting disease on the [¹⁸F]F-PSMA-PET/CT follow-up study.</div><div>45.3% (24/53) of patients with negative [¹⁸F]F-PSMA-PET/CT did not undergo PSRT. Of these, progressive PSA elevation was observed in 62.5% (15/24) (PSMA false negatives), localising recurrence on the [¹⁸F]F-PSMA-PET/CT follow-up study in 4 patients. The remaining 9 patients (37.5%) showed fluctuating PSA levels without detecting disease on the [¹⁸F]F-PSMA-PET/CT follow-up study.</div><div>Our series confirmed 42 (42.85%) [¹⁸F]F-PSMA-PET/CT false negatives cases.</div></div><div><h3>Conclusion</h3><div>Patients diagnosed with prostate cancer with post-prostatectomy biochemical recurrence and a negative [¹⁸F]F-PSMA-PET/CT study are likely to benefit from pelvic salvage radiotherapy, with response seen in 93.1% of our cases.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 2","pages":"Article 500071"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143510918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Técnica de marcaje con semilla radiactiva de 125-I en endometriosis inguinal","authors":"L. Rodríguez-Díaz ,&nbsp;E. García ,&nbsp;C. de Guirior ,&nbsp;R. Salvador ,&nbsp;J. Ribera-Perianes ,&nbsp;S. Vidal-Sicart","doi":"10.1016/j.remn.2024.500069","DOIUrl":"10.1016/j.remn.2024.500069","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 2","pages":"Article 500069"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amiloidosis intestinal secundaria visualizada en una gammagrafía con [99mTc]Tc-HMDP","authors":"S. Bondia-Bescós ,&nbsp;I.E. Sánchez-Rodríguez ,&nbsp;A. Palomar-Muñoz ,&nbsp;P. Notta ,&nbsp;M. Cortés-Romera ,&nbsp;L.M. Gràcia-Sánchez","doi":"10.1016/j.remn.2024.500070","DOIUrl":"10.1016/j.remn.2024.500070","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 2","pages":"Article 500070"},"PeriodicalIF":1.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diseminación metastásica muscular atípica detectada por PET/TC con 18F-FDG en leiomiosarcoma retroperitoneal de alto grado","authors":"R. Valverde-Jorge ,&nbsp;M. Díez-García ,&nbsp;I. Vinagre-Pérez ,&nbsp;L. Mosteiro-González ,&nbsp;I. Ratón Zulueta ,&nbsp;I. Fernández-Tercero","doi":"10.1016/j.remn.2024.500094","DOIUrl":"10.1016/j.remn.2024.500094","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 3","pages":"Article 500094"},"PeriodicalIF":1.6,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143868718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Características de imagen poco comunes de la osteomielitis multifocal recurrente crónica en adultos en PET/CT","authors":"R. Luo,&nbsp;W. Zhang,&nbsp;A. Kuang,&nbsp;Y. Li","doi":"10.1016/j.remn.2025.500121","DOIUrl":"10.1016/j.remn.2025.500121","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 3","pages":"Article 500121"},"PeriodicalIF":1.6,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143868720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparación de los rendimientos diagnósticos de la gammagrafía de perfusión miocárdica SPECT corregida por atenuación por TC y corregida sin atenuación en la enfermedad de las arterias coronarias","authors":"G. Kara Gedik ,&nbsp;A. Volkan Çelik ,&nbsp;M.U. Yalçın ,&nbsp;M. Koplay ,&nbsp;F. Yılmaz ,&nbsp;H. Önner","doi":"10.1016/j.remn.2024.500085","DOIUrl":"10.1016/j.remn.2024.500085","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Introduction and objectives&lt;/h3&gt;&lt;div&gt;Tissue attenuation reduces the specificity of the myocardial perfusion imaging single photon emission tomography (SPECT), which leads reduced diagnostic accuracy. The aim of this study is to compare performances of non-attenuation corrected (NAC), computed tomography based-attenuation corrected (AC) and prone images for qualitative and semi-quantitative analysis of myocardial perfusion SPECT in diagnosis of coronary artery disease (CAD).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Materials and methods&lt;/h3&gt;&lt;div&gt;Eighty six patients in whom NAC, AC and prone images were obtained with SPECT, and whose coronary angiography/CT coronary angiography was completed within 3 months, were retrospectively studied. Myocardial perfusion scintigraphy was performed using SPECT/CT dual-headed gamma camera. Images were evaluated qualitatively and semi-quantitatively using 20-segment model. Analyzes of global myocardium and LAD, RCA, Cx vascular areas as regional analysis were performed. In qualitative evaluation, if SPECT study was abnormal, relevant coronary artery area was recorded. Quantitative Perfusion SPECT (QPS) program was used in semi-quantitative analysis; Summed Stress Score (SSS)&lt;!--&gt; &lt;!--&gt;≥&lt;!--&gt; &lt;!--&gt;4 was accepted for presence of CAD in per-patient analysis. In regional analysis SSS&lt;!--&gt; &lt;!--&gt;≥&lt;!--&gt; &lt;!--&gt;2 was taken into account. Coronary angiography/CT coronary angiography was used as gold standard. Threshold value was determined as ≥&lt;!--&gt; &lt;!--&gt;50% and above luminal diameter narrowing. While AC and NAC methods were compared for per-patient analysis and each vascular area; 3&lt;!--&gt; &lt;!--&gt;imaging methods including prone acquisition, were compared for the RCA area. Diagnostic performances of the methods were evaluated by comparing the areas under the curve with ROC analysis.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;In visual evaluation, sensitivity of AC was significantly lower than NAC in analyzes of per-patient, RCA and Cx areas (global 76.92% vs 86.15%, RCA 60.87% vs 82.61%, Cx 58.97% vs 69.23%, respectively; &lt;em&gt;P&lt;/em&gt; &lt;!--&gt;&lt;&lt;!--&gt; &lt;!--&gt;.05). Sensitivity of prone imaging was significantly higher than AC in analysis of the RCA area (76.09% vs 60.87%, respectively; &lt;em&gt;P&lt;/em&gt; &lt;!--&gt;&lt;&lt;!--&gt; &lt;!--&gt;.05) Specificity values were higher in analyzes of global, RCA and Cx areas in AC than in NAC method; this difference was significant in RCA and Cx areas (RCA 70% vs 42.50%, Cx 85.11% vs 70.21%, respectively; &lt;em&gt;P&lt;/em&gt; &lt;!--&gt;&lt;&lt;!--&gt; &lt;!--&gt;.05). In semi-quantitative evaluation, AC and NAC had similar sensitivity and specificity in global and regional analyzes; in RCA area, no significant difference was detected between the 3&lt;!--&gt; &lt;!--&gt;methods. In ROC analysis, no significant difference was detected between methods in per-patient and regional analyzes both in visual and semi-quantitative evaluation.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;div&gt;CT-based attenuation correction increases specificity, but reduces sensitivity in the diagnosis of CAD in","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 3","pages":"Article 500085"},"PeriodicalIF":1.6,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143868615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aplicación práctica de la imagen multimodal en la cardio-oncología en América Latina","authors":"S. Malhotra ,&nbsp;A. Peix ,&nbsp;C. Gutierrez-Villamil ,&nbsp;M. Bazan ,&nbsp;R. Giubbini ,&nbsp;C. Cueva ,&nbsp;E. Estrada ,&nbsp;D. Paez","doi":"10.1016/j.remn.2024.500086","DOIUrl":"10.1016/j.remn.2024.500086","url":null,"abstract":"<div><div>Latin America is one of the regions in the world with the highest levels of overweight, dyslipidemia, and diabetes mellitus, which, together with smoking and high blood pressure, are common risk factors for cardiovascular and oncological diseases. Chemotherapy (CT) and radiotherapy (RT) have become two of the mainstays of treatment for several types of cancer. One of the most worrisome side effects generated by CT and RT is cardiotoxicity. There are several imaging techniques in cardiology that can inform the presence of underlying disease, but they differ in their availability and access to the masses, their accuracy and repeatability, all of which are important determinants of the applicability of these techniques in routine clinical practice. Thus, it is mandatory to promote a clinically effective and a cost-effective multimodality approach for risk stratification, diagnosis and management of cardiovascular diseases in oncologic patients. The purpose of this review is to inform cardiologists, oncologists, cardio-oncologists and imaging cardiologists on the cardiac imaging modalities that can be applied in patients with cancer, the differences among imaging techniques and recommendations on how to apply them in Latin America.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 3","pages":"Article 500086"},"PeriodicalIF":1.6,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}