Revista Espanola De Medicina Nuclear E Imagen Molecular最新文献

{"title":"PET-TC [18F]F-Colina y PTH intraoperatoria en el tratamiento quirúrgico del hiperparatiroidismo primario sin localización preoperatoria","authors":"F.G. García-García ,&nbsp;N. Cassinello Fernández ,&nbsp;J. Rodríguez Romera ,&nbsp;R. Martí Fernández ,&nbsp;M. Lapeña Rodríguez ,&nbsp;R. Alfonso Ballester ,&nbsp;R. Díaz Expósito ,&nbsp;J. Ortega Serrano","doi":"10.1016/j.remn.2024.500066","DOIUrl":"10.1016/j.remn.2024.500066","url":null,"abstract":"<div><h3>Background and objectives</h3><div>To assess the feasibility of performing selective parathyroidectomy without intraoperative parathyroid hormone (PTHio) determination when first-line preoperative localization tests (ultrasonography and [^99mTc]Tc-MIBI) are negative and/or discordant, and second-line [¹⁸F]F-Colina PET-CT, is positive.</div></div><div><h3>Materials and methods</h3><div>Retrospective cohort study, including patients with negative or discordant ultrasound and MIBI scans and positive [¹⁸F]F-Colina PET-CT, who underwent selective parathyroidectomy between 2019 and 2022. Groups were compared based on PTHio determination. Study variables were: gender, mean age, biochemical cure assessed by PTH value (pg/mL) and corrected calcium by albumin (mg/dL) at 6 months post-surgery follow-up, and histopathological analysis.</div></div><div><h3>Results</h3><div>The final sample included 42 patients. At 6 months post-surgery, in the PTHio group (20 patients), PTH values were 64.50 pg/mL and calcium 9.30 pg/mL, with 19 adenomas and 1 hyperplasia found. In the non-PTHio group (22 patients), PTH values were 61 pg/mL and calcium 9.37 pg/mL, with 22 adenomas found. No statistically significant differences were found between both groups.</div></div><div><h3>Conclusions</h3><div>Based on the results obtained in our patient cohort, selective parathyroidectomy could be considered with negative or discordant first-line tests and positive [¹⁸F]F-Colina PET-CT, without intraoperative PTH determination.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500066"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143105218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"18F-FDG PET/TC en la estadificación, evaluación terapéutica y seguimiento de un sarcoma prostático","authors":"I. Martínez-Rodríguez,&nbsp;F. Gómez-de la Fuente,&nbsp;A. Sánchez-Salmón,&nbsp;M. Pombo-López,&nbsp;A. Bota-Bota,&nbsp;R. Quirce","doi":"10.1016/j.remn.2024.500039","DOIUrl":"10.1016/j.remn.2024.500039","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500039"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143105219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remisión metabólica completa de neoplasia blástica generalizada de células dendríticas plasmocitoides tras tratamiento","authors":"N. Filizoglu ,&nbsp;S. Ozguven","doi":"10.1016/j.remn.2024.500040","DOIUrl":"10.1016/j.remn.2024.500040","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500040"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143105220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uso de propranolol en 18F-FDG-PET/TC para el diagnóstico diferencial de grasa parda en una paciente con antecedente de adenocarcinoma de cérvix uterino","authors":"A. Garcia Garcia ,&nbsp;A.P. Caresia Aróztegui ,&nbsp;S. Martínez Román","doi":"10.1016/j.remn.2024.500068","DOIUrl":"10.1016/j.remn.2024.500068","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500068"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efecto antitumoral de la vertebroplastia en la metástasis vertebral basado en el análisis cuantitativo de la PET/TC con 18F-FDG","authors":"L. Bian ,&nbsp;C. Yang ,&nbsp;S.-w. Yin ,&nbsp;C.-f. Ni","doi":"10.1016/j.remn.2024.500028","DOIUrl":"10.1016/j.remn.2024.500028","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500028"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gammagrafía peritoneal y SPECT/CT en el diagnóstico de fugas en pacientes en diálisis peritoneal","authors":"D. Tercero Garrido ,&nbsp;M.V. Guiote Moreno ,&nbsp;C. Rodelo-Haad ,&nbsp;P.I. Contreras Puertas ,&nbsp;S. Soriano Cabrera ,&nbsp;M.D. Albalá González","doi":"10.1016/j.remn.2024.500067","DOIUrl":"10.1016/j.remn.2024.500067","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the usefulness of peritoneal cavity scintigraphy and the contribution of SPECT/CT in patients on peritoneal dialysis with suspected leak.</div></div><div><h3>Methodology</h3><div>An observational case series study is carried out. It consists of a longitudinal, retrospective and descriptive study. 11 patients on peritoneal dialysis were studied and it was realiced a peritoneal cavity scintigraphy test and SPECT/CT to evaluate a peritoneal leak.</div></div><div><h3>Results</h3><div>In 54,5% of the patients, a positive study of peritoneal leak was obtained. The most frequent localitations were in the abdominal wall at the catheter entry level and the inguinal hernia. In the cases with sintomatology like pain and celullitis of the subcutaneous tract of the cateter the frequent of leak was 100%. There was a change in therapeutic management in patients with a positive study. There was not relevant changes in initial dialysis regimen in patients with a negative study. In this cases, except for one patient who required hemodialysis, all patients experienced clinical improvement.</div></div><div><h3>Conclusions</h3><div>Peritoneal scintigraphy and SPECT/CT study are non-invasive techniques that allow an adequate diagnosis and subsequent management of peritoneal leak.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500067"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143135593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Papel y aplicaciones de la 18F-FDG PET/TC en la evaluación de la infección e inflamación osteoarticular - Parte I","authors":"E. Noriega-Álvarez ,&nbsp;B. Rodríguez Alfonso ,&nbsp;J.J. Rosales Castillo ,&nbsp;A. Moreno Ballesteros ,&nbsp;E. López Rodríguez ,&nbsp;S. Sanz Viedma ,&nbsp;M. del P. Orduña Diez ,&nbsp;L. Domínguez Gadea","doi":"10.1016/j.remn.2024.500073","DOIUrl":"10.1016/j.remn.2024.500073","url":null,"abstract":"<div><div>¹⁸F-FDG PET/CT has been positioned over time as a useful tool in the evaluation of osteoarticular infections, overcoming conventional explorations like MRI or bone scintigraphy in some indications. Its ability to provide functional and anatomical images simultaneously and its excellent resolution contributes to a more precise and personalised approach in the treatment of osteoarticular diseases such as spondylodiscitis. In addition, it has proven valuable in patients with suspected infection that is complex to diagnose or treat, improving detection in subclinical stages. However, some limitations have been identified, such as difficulty in the differential diagnosis of infection vs. inflammation (as in diabetic foot) or in the interpretation of patients with osteosynthesis materials. In this manuscript, we present a brief review providing general and practical information about the role of ¹⁸F-FDG PET/CT in infectious osteoarticular pathology, while part 2 discusses the role of ¹⁸F-FDG PET/CT in osteoarticular inflammation.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500073"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143096746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Respuesta, complicaciones y riesgo de transformación leucémica del tratamiento con fósforo-32 en los síndromes mieloproliferativos crónicos Philadelphia negativos","authors":"I. Tobalina Larrea ,&nbsp;J. Cuetos Fernández ,&nbsp;A. Mendizabal Abad ,&nbsp;A. Montero de la Peña ,&nbsp;D. García Hernández ,&nbsp;G.H. Portilla Quatrociocchi ,&nbsp;M. Jiménez Alonso ,&nbsp;M.C. Menchaca Echevarria","doi":"10.1016/j.remn.2024.500064","DOIUrl":"10.1016/j.remn.2024.500064","url":null,"abstract":"<div><h3>Objective</h3><div>Describe our experience in treatment with Phosphorus-32 (³²P) for refractory Philadelphia negative chronic myeloproliferative syndromes or with side effects to the usual treatment, its complications and risk of leukemic transformation.</div></div><div><h3>Material and methods</h3><div>Retrospective descriptive study including 17 patients with a diagnosis of Philadelphia-negative chronic myeloproliferative syndrome treated with ³²P in our hospital from January 1985 to March 2017. Indications, response to treatment, as well as early and late complications have been analyzed.</div></div><div><h3>Results</h3><div>Of the 17 patients treated with ³²P (11 men, 6 women; mean age 79.8 years), 6 patients had polycythemia vera and 11 essential thrombocytosis. A single dose was administered in 9 of the subjects, the rest required 2 or more doses due to inadequate hematological response and/or relapse. The total dose range of ³²P administered was 116-951<!--> <!-->MBq (median: 236<!--> <!-->MBq). In 14 patients treated with ³²P, complete or partial response was achieved in hematimetry. In 11 patients, the response was complete, established as a platelet count<!--> <!-->&lt;<!--> <!-->400.000/mm³ in those diagnosed with essential thrombocythemia and a hematocrit<!--> <!-->&lt;<!--> <!-->45% in cases of polycythemia vera. The median follow-up of patients from the date of the first treatment of ³²P until study completion or death was 37 months (range: 5-230 months). Regarding early complications, 2 cases of anemia requiring blood transfusion were observed, and one case of mild thrombocytopenia. No leukemic transformation was identified.</div></div><div><h3>Conclusions</h3><div>In our experience, treatment with ³²P has been a useful therapeutic option in Philadelphia-negative chronic myeloproliferative syndromes in elderly patients who showed poor tolerance and/or resistance to first-line treatment. No leukemic transformation was identified.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500064"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143105221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlación entre respuesta metabólica determinada con [18F]FDG PET/TC y respuesta histológica tras tratamiento neoadyuvante y cirugía en pacientes con cáncer de esófago","authors":"J.R. Infante ,&nbsp;J. Quirós ,&nbsp;R. Barco ,&nbsp;C. Bejarano ,&nbsp;E. Agudo ,&nbsp;J. Fernández ,&nbsp;A. Baena ,&nbsp;A. Utrera ,&nbsp;A. Martínez ,&nbsp;C. Durán ,&nbsp;J. Serrano","doi":"10.1016/j.remn.2024.500088","DOIUrl":"10.1016/j.remn.2024.500088","url":null,"abstract":"<div><h3>Aim</h3><div>To assess the correlation between the result of the PET/CT study with [¹⁸F]FDG and the histological outcome in patients with esophageal cancer undergoing chemoradiotherapy and subsequent surgery.</div></div><div><h3>Material and methods</h3><div>41 patients (35 men) diagnosed with esophageal cancer during a 10-year interval were retrospectively evaluated. PERCIST criteria and SULpeak (ΔSULpeak) variation between pre- and post-treatment PET/CT studies were used. After neoadjuvant treatment and subsequent surgery, histological response and patient survival were determined, correlating the findings with the result of the metabolic study. Different parameters related to patient and tumors lesion characteristics were compared with respect to histologic response. ROC curves and the Kaplan-Meier method were applied for the analysis of prognostic factors and survival curves.</div></div><div><h3>Results</h3><div>The mean follow-up was 34.9 months, with 21 relapses-progressions and 25 deaths. Significant differences were demonstrated between histologic responses regarding PERCIST criteria and ΔSULpeak. Both showed adequate sensitivity and moderate specificity in relation to their histological correlation. No significant differences were found with respect to other parameters studied. Survival analysis showed significantly different progression-free survival curves for the ΔSULpeak and histologic outcome.</div></div><div><h3>Conclusion</h3><div>PERCIST criteria and ΔSULpeak differentiated between patients with and without histological response. ΔSULpeak and histological results proved to be prognostic factors. The results could help to personalize treatment and, together with other determinations, allow an active surveillance approach could be contemplated.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 3","pages":"Article 500088"},"PeriodicalIF":1.6,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Papel del [99mTc]Tc-DPD gated-SPECT-TC en la evaluación de los patrones de captación miocárdica de la amiloidosis por transtiretina (AC-TTR)","authors":"F. Sebastián Palacid ,&nbsp;N. Álvarez Mena ,&nbsp;M. García Aragón ,&nbsp;R.d.C. Zambrano Infantino ,&nbsp;B.M. Jaramillo López ,&nbsp;J. Gómez Hidalgo ,&nbsp;B. Pérez López ,&nbsp;M.P. Redondo del Río ,&nbsp;R. Ruano Pérez","doi":"10.1016/j.remn.2024.500081","DOIUrl":"10.1016/j.remn.2024.500081","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the feasibility of identifying various distribution patterns of [^99mTc]Tc-DPD in patients with cardiac transthyretin amyloidosis using gated SPECT-CT.</div></div><div><h3>Materials and methods</h3><div>Gated SPECT-CT was performed in patients with a positive scintigraphy result for cardiac amyloidosis due to transthyretin (TTR-CA). Patients were categorized into several groups based on sex, degree of radiopharmaceutical uptake according to the Perugini's visual scale and ventricular ejection fraction (LVEF). Cardiac polar maps were obtained using Emory Cardiac Toolbox™ software and scored by segments according to radiopharmaceutical uptake on a scale from 0 (no uptake) to 4 (very high uptake intensity). The Mann-Whitney U and Pearson's Chi-square statistical tests were employed to identify significant differences in distribution patterns according to the different variables under study.</div></div><div><h3>Results</h3><div>A total of 65 patients were evaluated. The gender variable determined the main statistically significant differences, highlighting distinct distribution patterns of the radiopharmaceutical at the cardiac level: while women showed lower accumulation of [^99mTc]Tc-DPD in the middle anterior (<em>P</em> <!-->=<!--> <!-->0.035) and basal anterior (<em>P</em> <!-->=<!--> <!-->0.001) segments, whereas men demonstrated higher accumulation in the basal anteroseptal (<em>P</em> <!-->=<!--> <!-->0.009) and basal inferoseptal (<em>P</em> <!-->=<!--> <!-->0.009) segments, and lower scores in the lateroapical segment (<em>P</em> <!-->=<!--> <!-->0.039).</div></div><div><h3>Conclusions</h3><div>Gated SPECT-CT is an essential tool for assessing the distribution pattern of [^99mTc]Tc-DPD of patients with TTR-CA, offering valuable insights into the pathophysiology of the disease.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 3","pages":"Article 500081"},"PeriodicalIF":1.6,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}