Andrew G. Guzick , Sophie C. Schneider , Amanda B. Perozo Garcia , Minjee Kook , Rebecca L. Greenberg , David Riddle , Morgan McNeel , Servando Rodriguez-Barajas , Michelle Yang , Blake Upshaw , Eric A. Storch
{"title":"Development and pilot testing of internet-delivered, family-based cognitive behavioral therapy for anxiety and obsessive-compulsive disorders in autistic youth","authors":"Andrew G. Guzick , Sophie C. Schneider , Amanda B. Perozo Garcia , Minjee Kook , Rebecca L. Greenberg , David Riddle , Morgan McNeel , Servando Rodriguez-Barajas , Michelle Yang , Blake Upshaw , Eric A. Storch","doi":"10.1016/j.jocrd.2023.100789","DOIUrl":"10.1016/j.jocrd.2023.100789","url":null,"abstract":"<div><p><span>Cognitive behavioral therapy adapted for autistic youth with anxiety and/or </span>OCD<span><span> has a strong evidence base, but few have access. A 12-week family-based, Internet-delivered cognitive behavioral therapy (iCBT) program for 7-15 year-old autistic youth with anxiety and/or OCD was developed as a potential method to address this problem. Quantitative and qualitative feedback from stakeholders (parents, youth, clinicians) was gathered on an initial draft of content before conducting a pilot trial. This feedback suggested high quality, engagement, usability, and informativeness of the material. Suggestions were incorporated into the treatment program that was tested in a pilot trial. Eight families were randomized to the iCBT program with either 1) weekly email support or 2) weekly email support plus biweekly </span>telehealth check-ins, and seven of these families completed pre- and post-treatment assessments. An average reduction of 39% in anxiety severity scores was found, with six of the seven being classified as responders. Preliminary evidence suggests that family-based iCBT is an acceptable and promising treatment for autistic youth with anxiety and/or obsessive-compulsive disorders that should be further modified and tested in future work.</span></p></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"37 ","pages":"Article 100789"},"PeriodicalIF":1.8,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9168809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samuel D. Spencer , Jordan T. Stiede , Andrew D. Wiese , Andrew G. Guzick , Matti Cervin , Dean McKay , Eric A. Storch
{"title":"Things that make you go Hmm: Myths and misconceptions within cognitive-behavioral treatment of obsessive-compulsive disorder","authors":"Samuel D. Spencer , Jordan T. Stiede , Andrew D. Wiese , Andrew G. Guzick , Matti Cervin , Dean McKay , Eric A. Storch","doi":"10.1016/j.jocrd.2023.100805","DOIUrl":"10.1016/j.jocrd.2023.100805","url":null,"abstract":"<div><p><span>The past four decades have yielded a robust body of evidence supporting the efficacy and effectiveness of cognitive-behavioral therapy (CBT) as a gold-standard treatment for obsessive-compulsive disorder (OCD) across the lifespan. Exposure and response prevention (E/RP) has been identified as a key component of this approach. Despite robust research support for CBT with E/RP, several myths and misconceptions continue to proliferate in both research and practice settings. Such myths and misconceptions are concerning, as they lack empirical basis, may hinder widespread dissemination and implementation of CBT for OCD, and run contrary to the practice of evidence-based psychological medicine. Focusing on the importance of promoting evidence-based practice and generative </span>clinical science, the present review article synthesizes relevant research within the field of treatments for OCD to address the following myths/misconceptions: (a) uncertainty exists concerning the evidence base supporting CBT for OCD, (b) E/RP attrition and dropout rates are unacceptably high due to excessive risk and perceived patient intolerability, and (c) alternative treatments for OCD need to be expeditiously developed due to major limitations of E/RP. Recommendations for future research and clinical dissemination and implementation to further advance a generative clinical science of OCD treatment are discussed.</p></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"37 ","pages":"Article 100805"},"PeriodicalIF":1.8,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9540507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using item response theory to investigate potential gender bias in hoarding symptoms","authors":"K.R. Timpano , Z.T. Goodman , M.L. Kushner , S.E. Hudiburgh , C.I. Rodriguez , J.R. Grisham","doi":"10.1016/j.jocrd.2023.100788","DOIUrl":"10.1016/j.jocrd.2023.100788","url":null,"abstract":"<div><p><span>Gender and/or sex differences<span> in the prevalence of hoarding disorder have been well documented, yet there remains a striking lack of understanding as to potential reasons. Critically no study to date has examined whether gender differences may stem from underlying biases in hoarding assessment instruments. The current study used item response theory to evaluate the Saving Inventory-Revised (SI-R; Frost et al., 1994), to determine if there might be differential item functioning (DIF) between men and women across the three core features of hoarding. We first examined responses in a sample of individuals with clinically significant hoarding symptoms (N = 255), and then replicated our findings in a non-selected community sample (N = 719). There was evidence of modest DIF, which affected only a handful of items in each SI-R subscale. In the clinical sample, women scored significantly higher on the clutter and acquisition latent continuum, whereas there was no </span></span>gender difference for difficulties discarding. In contrast, there were no gender differences in any of the subscales for the community sample. Findings indicate that while there are likely gender differences in the manifestation and associated features of hoarding, those gender differences are not the result of measurement artifacts in the SI-R.</p></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"37 ","pages":"Article 100788"},"PeriodicalIF":1.8,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49668281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephan Siwiec, Sarah Bodhy, Salahadin Lotfi, Han-Joo Lee
{"title":"Cognitive bias modification for thought-action fusion: A placebo-controlled randomized experimental trial","authors":"Stephan Siwiec, Sarah Bodhy, Salahadin Lotfi, Han-Joo Lee","doi":"10.1016/j.jocrd.2023.100787","DOIUrl":"10.1016/j.jocrd.2023.100787","url":null,"abstract":"","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"37 ","pages":"Article 100787"},"PeriodicalIF":1.8,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48581573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kelly A. Knowles, Sarah C. Jessup, Bunmi O. Olatunji
{"title":"Facing uncertainty: A comparison of hierarchical and variable exposure interventions for contamination fear","authors":"Kelly A. Knowles, Sarah C. Jessup, Bunmi O. Olatunji","doi":"10.1016/j.jocrd.2022.100777","DOIUrl":"10.1016/j.jocrd.2022.100777","url":null,"abstract":"<div><p>Consistent with the inhibitory retrieval approach, one proposed modification to improve the effectiveness of exposure-based interventions is to maximize variability by not proceeding linearly up an exposure hierarchy. Accordingly, the present study compares hierarchical and variable exposure interventions for contamination-fearful individuals and examines the role of uncertainty to predict intervention outcomes. Participants (<em>N</em> = 73) were randomly assigned to complete a single-session exposure intervention using a standard hierarchy or a variable exposure intervention in which hierarchy items were randomly presented. Participants completed a behavioral approach task (BAT) at baseline and two follow-up visits over a two-week period. Both interventions resulted in a significant decrease in anxiety and disgust as well as more BAT steps completed but did not differ from one another. However, individuals in the variable exposure condition reported <em>less</em> variability in uncertainty during exposure compared to those in the standard condition, <em>d</em> = .78. Furthermore, lower levels of variability in uncertainty predicted greater reductions in anxiety and disgust post-intervention. Consistent with previous studies, variable exposure did not convey additional benefit over standard, hierarchical exposure. The experience of uncertainty during exposure is an important yet understudied process that warrants additional investigation.</p></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"36 ","pages":"Article 100777"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9471029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reassurance and its alternatives: Overview and cognitive behavioural conceptualisation","authors":"Brynjar Halldorsson , Paul M. Salkovskis","doi":"10.1016/j.jocrd.2023.100783","DOIUrl":"10.1016/j.jocrd.2023.100783","url":null,"abstract":"","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"36 ","pages":"Article 100783"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43978677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wenting Chen , Skye McDonald , Travis Wearne , Isaac Sabel , Emma V. Long , Jessica R. Grisham
{"title":"A pilot study of adapted social cognition and intervention training (SCIT) for hoarding disorder","authors":"Wenting Chen , Skye McDonald , Travis Wearne , Isaac Sabel , Emma V. Long , Jessica R. Grisham","doi":"10.1016/j.jocrd.2022.100776","DOIUrl":"10.1016/j.jocrd.2022.100776","url":null,"abstract":"<div><h3>Background</h3><p><span>Emerging research has suggested that hoarding may be associated with reduced social cognition<span>, specifically reduced theory of mind and hostility biases, which may contribute to the social difficulties observed in this population. The primary aim of this study was to evaluate the feasibility and acceptability of Social Cognition and Interaction Training (SCIT) in a sample of individuals with </span></span>Hoarding Disorder<span> (HD) and assess its potential as an adjunct to CBT. We secondarily examined changes in loneliness and hoarding symptoms.</span></p></div><div><h3>Methods</h3><p>Twelve individuals, with a primary diagnosis of HD, completed a 12-week SCIT program and one booster session. Participants were assessed at pre-treatment, mid-treatment, post-treatment, and one-month follow-up on measures of theory of mind, attributional style, hoarding symptom severity, and loneliness.</p></div><div><h3>Results</h3><p>From pre-to post-treatment, participants had an improvement in theory of mind for sarcastic remarks and a reduction in hostility bias, hoarding symptoms, and loneliness. Retention was also good as all participants completed treatment.</p></div><div><h3>Conclusion</h3><p>These preliminary results suggest that SCIT is a promising treatment to improving social cognition for hoarding disorder and may improve interpersonal difficulties such as loneliness. We propose that SCIT may represent a potential adjunct targeting social factors to improve the efficacy of CBT.</p></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"36 ","pages":"Article 100776"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47402405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily E. Bernstein , Hilary Weingarden , Jennifer L. Greenberg , Jasmine Williams , Susanne S. Hoeppner , Ivar Snorrason , Katharine A. Phillips , Oliver Harrison , Sabine Wilhelm
{"title":"Credibility and expectancy of smartphone-based cognitive behavioral therapy among adults with body dysmorphic disorder","authors":"Emily E. Bernstein , Hilary Weingarden , Jennifer L. Greenberg , Jasmine Williams , Susanne S. Hoeppner , Ivar Snorrason , Katharine A. Phillips , Oliver Harrison , Sabine Wilhelm","doi":"10.1016/j.jocrd.2023.100781","DOIUrl":"10.1016/j.jocrd.2023.100781","url":null,"abstract":"<div><h3>Background</h3><p><span>Few patients receive cognitive behavioral therapy, the gold-standard for </span>body dysmorphic disorder (CBT-BDD). Smartphones can make evidence-based interventions, like CBT-BDD, more accessible and scalable. A key question is: how do patients view it? Low credibility and expectancy would likely translate to low uptake and engagement outside of research settings, diminishing the impact. Thus, it is important to understand patients’ beliefs about digital CBT-BDD.</p></div><div><h3>Methods</h3><p>We compared credibility and expectancy in a coach-guided app-based CBT-BDD trial (N = 75) to a previous in-person CBT-BDD trial (N = 55). We further examined the relationship of perceptions of digital CBT-BDD to baseline clinical and demographic factors and dropout.</p></div><div><h3>Results</h3><p>Credibility did not differ between the in-person (<em>M</em> = 19.3) and digital (<em>M</em> = 18.3) trials, <em>p</em> = .24. Expectancy for improvement was moderately higher for in-person (<em>M</em> = 58.4) than digital (<em>M</em><span> = 48.3) treatment, </span><em>p</em> = .005. In the digital trial, no demographic variables were associated with credibility or expectancy. Better BDD-related insight and past non-CBT BDD therapy were associated with greater expectancy. Credibility was associated with lower likelihood of dropout.</p></div><div><h3>Discussion</h3><p>Digital CBT-BDD was regarded as similarly credible to in-person CBT-BDD but with lower expectancy. Tailored expectancy-enhancing strategies could strengthen this novel approach, particularly among those with poorer insight and without prior BDD treatment.</p></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"36 ","pages":"Article 100781"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45979944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Robert R. Selles , John R. Best , Cynthia Lu , Noam Soreni , Lara J. Farrell , Sharna Mathieu , S. Evelyn Stewart
{"title":"Challenges of insight assessment in pediatric obsessive-compulsive disorder: Initial results and clinical considerations from a measure development study","authors":"Robert R. Selles , John R. Best , Cynthia Lu , Noam Soreni , Lara J. Farrell , Sharna Mathieu , S. Evelyn Stewart","doi":"10.1016/j.jocrd.2022.100774","DOIUrl":"10.1016/j.jocrd.2022.100774","url":null,"abstract":"<div><h3>Background</h3><p>Assessing insight among OCD-affected youth has been limited by the absence of a multi-item measure for this population. The present study outlines the development of the <em>Measure of Insight for Obsessive-Compulsive Disorder</em> (MI-OCD), presents initial findings, and explores conceptual challenges.</p></div><div><h3>Methods</h3><p>Along with the <em>Children's Yale-Brown Obsessive-Compulsive Scale</em> (CY-BOCS), the 7-item MI-OCD was administered to 178 OCD-affected youth aged 7–19 (mean age = 13.5, SD = 2.8; 55% female) presenting for assessment across three OCD-specialty clinics. Items 4–7 were only completed by those with an identified feared outcome (61%).</p></div><div><h3>Results</h3><p>MI-OCD items were positively correlated with the CY-BOCS’ insight question, but were not related to age or avoidance. Correlations and factor analysis indicated items coalesced around concepts of symptoms as unwanted (1–3) and symptoms as useful/valid (4–7), although factor fit and internal consistency was sub-optimal. Most youth perceived their symptoms as unwanted (positively correlated with severity), while the extent to which youth perceived symptoms as useful was more varied (not associated with severity).</p></div><div><h3>Discussion</h3><p>Insight remains a challenging construct to assess in youth given various developmental, psychological, and environmental confounds. The MI-OCD may be useful in the context of evaluating and addressing individual barriers to treatment engagement over time.</p></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"36 ","pages":"Article 100774"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45210009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toward a biopsychosocial model of hoarding disorder","authors":"David F. Tolin","doi":"10.1016/j.jocrd.2022.100775","DOIUrl":"10.1016/j.jocrd.2022.100775","url":null,"abstract":"<div><p><span><span>The present paper aims to elaborate on the original cognitive-behavioral model of hoarding disorder<span> (HD; Frost & Hartl, 1996) by incorporating the results of recent research on biological and psychological contributors to HD. According to the proposed model, HD is characterized by several vulnerability factors that are thought to increase the likelihood that HD will develop, including genetic predisposition, abnormalities of brain structure, </span></span>environmental factors<span> such as traumatic life experiences, neuroticism, and impairments of cognitive function. Superimposed on these vulnerability factors is a biphasic abnormality of central and </span></span>peripheral nervous system<span> activity; at rest, or when doing completing symptom-irrelevant tasks, individuals with HD show blunted activity in brain regions that make up the salience network<span>, including anterior cingulate cortex<span><span> and insula. This blunted reactivity is further demonstrated through diminished error-related negativity (ERN) and decreased physiological arousal during error trials. However, when individuals with HD make decisions about possessions, they show relative </span>hyperactivation of the salience network (and other brain regions), with accompanying indecisiveness, negative affect, exaggerated ERN, increased physiological arousal, and activation of maladaptive beliefs about, and attachment to, possessions. These factors lead to acquiring and saving behaviors, which are subsequently reinforced through emotion modification.</span></span></span></p></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"36 ","pages":"Article 100775"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45852014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}