Journal of Obsessive-Compulsive and Related Disorders最新文献

{"title":"A cognitive intervention for negative beliefs about losing control: impact on other cognitive domains and OCD symptoms","authors":"Andrea Sandstrom,&nbsp;Adam S. Radomsky","doi":"10.1016/j.jocrd.2025.100966","DOIUrl":"10.1016/j.jocrd.2025.100966","url":null,"abstract":"<div><h3>Purpose</h3><div>Beliefs about losing control have been proposed as a novel cognitive domain in OCD. Despite increasing evidence that links these beliefs with OCD symptoms, it is unclear whether interventions targeting beliefs about losing control lead to symptom improvement. This study sought to develop and test the impact of a brief cognitive intervention for beliefs about losing control on OCD-relevant appraisals and symptoms in a sub-clinical OCD sample.</div></div><div><h3>Methods</h3><div>A total of 35 sub-clinical participants were recruited based on self-reported OCD symptoms and beliefs about losing control, and randomly assigned to receive a 1-h CBT session targeting beliefs about losing control (intervention) or sleep hygiene (control). Beliefs about losing control, and OCD symptom were assessed at baseline and one week after the intervention using self-report questionnaires. Appraisals of losing control and OCD-relevant appraisals were also assessed using daily monitoring forms during the two-week intervention period.</div></div><div><h3>Results</h3><div>There was a significant interaction between condition and time on appraisals of losing control and OCD-relevant appraisals measured by the daily monitoring forms, with those in the intervention condition showing greater reductions from baseline to follow-up compared to those in control condition. There were no significant interaction effects on beliefs about losing control or OCD symptoms measured using standardized self-report questionnaires.</div></div><div><h3>Conclusions</h3><div>These results suggest that incorporating strategies targeting beliefs about losing control into CBT for OCD may be warranted, however more time and/or sessions is/are likely required to achieve broader symptom improvement.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"46 ","pages":"Article 100966"},"PeriodicalIF":1.9,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144280647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seeing beyond the diagnostic and statistical manual: A function-centered review of obsessive-compulsive disorder and anxiety disorders","authors":"Jón Ingi Hlynsson ,&nbsp;Jan Bergström ,&nbsp;Per Carlbring","doi":"10.1016/j.jocrd.2025.100967","DOIUrl":"10.1016/j.jocrd.2025.100967","url":null,"abstract":"<div><div>Obsessive-compulsive disorder (OCD) is classified within its own diagnostic category, separate from anxiety disorders, yet clinical practitioners still treat it as an anxiety disorder; both conceptually and therapeutically. This paper examines the rationale for seperating OCD from the anxiety disorders by contrasting cognitive models of anxiety disorders and OCD, and reviewing phenomenological and psychobiological evidence for OCD's distinctiveness. We compare OCD's behavioral functions with those of specific phobia, panic disorder, agoraphobia, social anxiety disorder, generalized anxiety disorder, and health anxiety disorder. Our review finds no compelling evidence that OCD differs sufficiently from anxiety disorders to warrant its own category. The same functional behaviors are evident in OCD and other anxiety disorders, with the foci of threat being the differentiating factor between disorders (e.g., fear of public speaking vs. fear of contamination in social anxiety and contamination-OCD, respectively). Consequently, we conclude by emphasizing that future research should focus on behavioral function when studying mental disorders, since descriptive similarities may not indicate clinical or functional equivalence. For diagnostic manuals to maintain validity and clinical utility, they must incorporate a functional analytic perspective. Failure to do so may result in inadequate diagnostic categories and stagnant treatment advances (cf. clinical guidelines for OCD have remained unchanged since 2005). While diagnostic manuals are meant to guide treatment selection, descriptive diagnoses need complementary theory-driven case conceptualizations to advance our understanding of maintaining factors and mechanisms of change during treatment. Without this approach, theoretical progress in OCD may stall, ultimately affecting patient outcomes.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"46 ","pages":"Article 100967"},"PeriodicalIF":1.9,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144306769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric evaluation of the Indonesian Yale–Brown Obsessive-Compulsive Scale—Second Edition","authors":"Riangga Novrianto ,&nbsp;Christiana L. Ticoalu ,&nbsp;P. Tommy Y.S. Suyasa ,&nbsp;Steffi Hartanto ,&nbsp;Wayne K. Goodman ,&nbsp;Eric A. Storch ,&nbsp;Edo S. Jaya","doi":"10.1016/j.jocrd.2025.100965","DOIUrl":"10.1016/j.jocrd.2025.100965","url":null,"abstract":"<div><div>The Yale-Brown Obsessive-Compulsive Scale Second Edition (Y-BOCS-II) is the gold-standard measure of obsessive-compulsive disorder (OCD) severity, yet no validated Indonesian version exists. This study evaluated the psychometric properties of the Indonesian Y-BOCS-II in 141 adult outpatients with OCD. The Y-BOCS-II demonstrated excellent internal consistency (KR-20 = 0.90 for Symptom Checklist and <em>ω</em> = 0.94 for Severity Scale), strong inter-rater reliability (ICC = 0.99), and high temporal stability over two weeks (ICC = 0.90). Confirmatory factor analyses revealed poor fit for both the original obsession/compulsion and alternative interference/control two-factor models. However, three-factor model (Time/Frequency, Resistance/Control, Distress/Interference) demonstrated acceptable fit (RMSEA = 0.09, CFI = 0.97, SRMR = 0.04). The scale demonstrated convergent validity with the Obsessive-Compulsive Inventory-Revised and Florida Obsessive-Compulsive Inventory Severity Scale, while maintaining discriminant validity from Patient Health Questionnaire - 9 and Generalized Anxiety Disorder - 7. These findings establish the Indonesian Y-BOCS-II as a reliable and valid measure for assessing OCD symptoms in Indonesian clinical settings and suggest presence of a three-factor conceptualization of OCD symptomatology.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"46 ","pages":"Article 100965"},"PeriodicalIF":1.9,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144254514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Compulsions in trauma-exposed patients with obsessive-compulsive disorder: Differences in prevalence and impact on treatment response","authors":"Caitlin M. Pinciotti ,&nbsp;Gregor Horvath ,&nbsp;Matti Cervin","doi":"10.1016/j.jocrd.2025.100964","DOIUrl":"10.1016/j.jocrd.2025.100964","url":null,"abstract":"<div><div>The effectiveness of exposure and response prevention (ERP), a front-line treatment for obsessive-compulsive disorder (OCD), is contingent on reducing engagement in compulsions, though recent research has found that certain compulsions may be less amenable to ERP. Given the impact of trauma exposure on OCD compulsions, the present study sought to examine whether compulsion-specific differences in treatment response may be attributable to trauma exposure. Using a sample of 622 patients diagnosed with OCD receiving intensive treatment (39.7 % trauma-exposed), certain compulsions were found to be more prevalent among trauma-exposed patients and differentially impacted treatment effectiveness. Trauma-exposed patients were more likely to engage in reassurance, rumination, and hair pulling, and less likely to engage in self-assurance compulsions compared to non-trauma exposed patients. Interestingly, among trauma-exposed patients, engaging in self-assurance compulsions was associated with better treatment outcomes and engaging in reassurance compulsions was associated with worsened treatment outcomes. Findings converge with trauma-focused treatment approaches, wherein functional self-assurance is not only permitted but encouraged. Although historically any form of assurance in ERP is discouraged, clinicians treating trauma-exposed patients with OCD may consider leveraging engagement in non-compulsive self-assurance to increase self-efficacy and treatment motivation and challenge distorted trauma-related beliefs. Findings highlight the importance of considering with nuance the function of underlying behaviors.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"46 ","pages":"Article 100964"},"PeriodicalIF":1.9,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144212580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prevalence of aggressive obsessions in youth with obsessive-compulsive disorder: A meta-analysis","authors":"Olivia C. Bishop ,&nbsp;Brooke Hiscock ,&nbsp;Quinn Morris ,&nbsp;Chelsea Lahey ,&nbsp;Charlotte Corran ,&nbsp;Sandra Krause ,&nbsp;Jonathan M. Fawcett ,&nbsp;Emily J. Fawcett","doi":"10.1016/j.jocrd.2025.100963","DOIUrl":"10.1016/j.jocrd.2025.100963","url":null,"abstract":"<div><div>Despite obsessive-compulsive disorder (OCD) being a recognizable psychiatric disorder, certain presentations of OCD are still highly stigmatized and misidentified by healthcare professionals. Namely, aggressive obsessions, which include ego-dystonic, intrusive thoughts and fears of accidentally or intentionally harming the self or others, are vastly under researched. With current prevalence estimates for aggressive obsessions in pediatric OCD ranging anywhere from 30.8 % to 86 %, the primary aim of the current meta-analysis was to provide the first meta-analytic estimate of the worldwide prevalence of aggressive obsessions among youth with OCD. A secondary goal of this study was to quantify sources of heterogeneity that contribute to the variability in prevalence estimates to date. A systematic review was conducted in Covidence using the following online databases: PsycINFO, PubMed, and CINAHL. Of the 4218 articles imported and screened, 831 received a full-text review, with 27 studies (<em>N</em> = 3428) ultimately coded. Using a random-effects model, the aggregate lifetime prevalence rate of aggressive obsessions was found to be 65.1 % <em>CI</em>_{<em>95 %</em>} [57.3 %, 72.2 %], with prediction intervals ranging from 43.9 % to 81.7 %, and a current prevalence rate of 61.9 % <em>CI</em>_{<em>95 %</em>} [56.4 %, 67.0 %], with prediction intervals ranging from 37.0 % to 81.8 %. The presence of comorbidities and the type of diagnostic measure utilized were found to be significant moderators for current estimates. With over half of youth experiencing aggressive obsessions in their lifetime, continuing education is required for healthcare professionals to be able to identify and properly treat this common, but often overlooked, symptom dimension.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"46 ","pages":"Article 100963"},"PeriodicalIF":1.9,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144205436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identity – OCD","authors":"Jeffrey M. Cohen ,&nbsp;Brian A. Feinstein ,&nbsp;Caitlin M. Pinciotti","doi":"10.1016/j.jocrd.2025.100962","DOIUrl":"10.1016/j.jocrd.2025.100962","url":null,"abstract":"","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"46 ","pages":"Article 100962"},"PeriodicalIF":1.9,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144205437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk-aversion with both high and low ambiguity: Elevated OCD symptom severity and intolerance of uncertainty are associated with less risk-taking in an OCD patient sub-sample","authors":"Ryan J. Jacoby ,&nbsp;Dalton L. Klare ,&nbsp;Caroline H. Armstrong ,&nbsp;Susanne S. Hoeppner ,&nbsp;Jennifer Lerner ,&nbsp;Sabine Wilhelm","doi":"10.1016/j.jocrd.2025.100955","DOIUrl":"10.1016/j.jocrd.2025.100955","url":null,"abstract":"<div><div>In clinical settings, patients with obsessive compulsive disorder (OCD) are generally risk-averse, especially in the context of uncertainty. However, the literature examining risk-taking in OCD is conflicting, and studies directly comparing risk-taking under conditions of high versus low ambiguity are scant. In the current study, 60 participants (30 OCD, 30 non-psychiatric controls) completed a modified version of the Balloon Analogue Risk Task (BART) in which they “pumped” a virtual balloon and earned five cents for each pump; however, if the balloon popped, they lost the money accumulated in that round. The task had two levels of ambiguity: the risk level of each balloon (i.e., likelihood of it exploding) was either visually displayed (low ambiguity) or unknown (high ambiguity). The outcome was the average number of pumps for balloons that did not explode, with higher scores indicating more risk-taking. There was a main effect of ambiguity, such that participants took more risks on the low ambiguity BART compared to the high ambiguity version. Contrary to hypotheses, there was no ambiguity level x diagnostic group interaction. Within the OCD group, however, intolerance of uncertainty, OCD symptom severity, trait anxiety, and depression severity were negatively associated with risk-taking. Without a clinical control group, we're unable to determine specificity of these effects to OCD. The within-subjects design may have contributed to carryover effects. Findings underscore the importance of symptom dimensional measurement beyond mere presence or absence of diagnosis when predicting risk-aversion in OCD.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"46 ","pages":"Article 100955"},"PeriodicalIF":1.9,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144254515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of ecological momentary assessment methods and designs in the context of obsessive-compulsive disorder: A systematic review","authors":"Rui Braga ,&nbsp;Divo Faustino ,&nbsp;Maria João Faria ,&nbsp;Miguel M. Gonçalves ,&nbsp;Julian Rubel ,&nbsp;João Tiago Oliveira","doi":"10.1016/j.jocrd.2025.100952","DOIUrl":"10.1016/j.jocrd.2025.100952","url":null,"abstract":"<div><h3>Background</h3><div>Ecological momentary assessment (EMA) is becoming an increasingly prevalent methodology in the field of obsessive-compulsive disorder (OCD) research, offering a means of capturing symptom fluctuations in real-time. Although its flexibility allows it to be adapted to a wide range of study objectives, there is currently no comprehensive study of EMA designs in OCD research.</div></div><div><h3>Methods</h3><div>A systematic search identified 34 studies that employed EMA with patients diagnosed with OCD. Data were extracted on the study objectives, sampling schedules, data collection platforms, response scales, and variables assessed. Items content was subjected to qualitative analysis to categorize the theme assessed.</div></div><div><h3>Results</h3><div>There was considerable variation in the studies’ designs. The mean duration of data collection varied from one to seven days, with an average of four daily assessments. A total of 374 items were extracted, and 12 themes were identified. The most frequent item themes were related to OCD symptoms (49.7 %) and mood/emotions (27 %). The platforms used included digital devices (35.3 %) and traditional pen-and-paper methods (58.8 %). Response rates, reported in only 32.4 % of studies, averaged 74.2 %, while dropout rates averaged 24.8 %. The variability of the methods underlined the adaptability of EMA, but also highlighted standardization challenges.</div></div><div><h3>Conclusions</h3><div>Item themes related to OCD symptoms and mood were dominant, reflecting the focus of EMA on capturing dynamic processes. Summarising the methodological trends identified in this review provides a foundation for improving design and standardization in future EMA-based OCD research.</div></div><div><h3>Systematic review registration</h3><div>[CRD42023406887].</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"45 ","pages":"Article 100952"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143807124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Four questions for clarity: A first investigation of the German version of the OCI-4 as an ultra-brief screening tool for Obsessive-Compulsive Disorder","authors":"Celina L. Müller ,&nbsp;Lena Jelinek ,&nbsp;Jakob Fink-Lamotte ,&nbsp;Jakob Scheunemann ,&nbsp;Dean McKay ,&nbsp;Jonathan S. Abramowitz ,&nbsp;Amitai Abramovitch ,&nbsp;Barbara Cludius","doi":"10.1016/j.jocrd.2025.100953","DOIUrl":"10.1016/j.jocrd.2025.100953","url":null,"abstract":"<div><h3>Background</h3><div>Obsessive-Compulsive Disorder (OCD) is a prevalent and debilitating condition that is frequently under- or misdiagnosed in clinical practice, leading to significant delays between symptom onset and accurate diagnosis. To improve the diagnostic process for individuals with OCD, there is an urgent need for screening instruments that are both syndromally valid and reliable. Accordingly, the current study aims to evaluate the psychometric properties of the German version of the ultra-brief, four-item Obsessive-Compulsive Inventory (OCI-4).</div></div><div><h3>Methods</h3><div>The psychometric properties of the OCI-4 were investigated in a German-speaking sample composed of 102 participants with OCD, 69 participants with an anxiety-related disorder, and 248 non-clinical individuals.</div></div><div><h3>Results</h3><div>The OCI-4 showed good test-retest reliability, moderate-to-good construct validity, and good-to-excellent screening accuracy.</div></div><div><h3>Conclusions</h3><div>The results support that the German version of the OCI-4 is a valid and reliable screening tool for OCD symptoms with good-to-excellent psychometric properties. The OCI-4 could be established as a screening tool in various settings to identify those with likely OCD.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"45 ","pages":"Article 100953"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143923944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the Family Accommodation Scale – Anxiety (parent- and child-report) and Coercive Disruptive Behavior Scale for Pediatric OCD in Dutch pediatric OCD patients","authors":"Olav van Groot Battavé ,&nbsp;Julia D.K. Veeger ,&nbsp;Kees J. Kan ,&nbsp;Elisabeth M.W.J. Utens ,&nbsp;Chaim Huijser ,&nbsp;Luuk Stapersma","doi":"10.1016/j.jocrd.2025.100954","DOIUrl":"10.1016/j.jocrd.2025.100954","url":null,"abstract":"<div><h3>Introduction</h3><div>Family accommodation (FA) and coercive-disruptive behaviors are critical factors in the development, severity and treatment outcome of pediatric obsessive-compulsive disorder (OCD). Validated questionnaires assessing the degree of FA and coercive-disruptive behaviors are urgently needed to improve treatment outcomes for pediatric OCD.</div></div><div><h3>Aims</h3><div>To validate the Family Accommodation Scale – Anxiety (FASA parent-report), FASA child-report (FASA-CR) and Coercive Disruptive Behavior Scale for Pediatric OCD (CD-POC, parent-report) in a Dutch pediatric OCD population.</div></div><div><h3>Methods</h3><div>A confirmatory factor analysis (CFA) was performed on the first 9 items of the FASA and FASA-CR on both the clinical group and combined sample of clinical (N = 90) and control participants (N = 90), aged 8 to 18. Internal consistency, convergent validity and criterion validity of the FASA, FASA-CR and CD-POC were investigated.</div></div><div><h3>Results</h3><div>CFA supported the two-factor structure of the original FASA(-CR), indicating good fit. FASA(-CR)'s internal consistency ranged from .88 to .95. Positive correlations were found between parent-reported FA, child-reported FA and coercive-disruptive behaviors. Both parent- and child-report FA were positively correlated with OCD-symptom screening, OCD-severity and parenting stress. CD-POC's internal consistency ranged from .91 to .94. The FASA and CD-POC showed excellent- and the FASA-CR considerable criterion validity in distinguishing children with OCD from those without.</div></div><div><h3>Conclusion</h3><div>Findings support the reliability and validity of the Dutch FASA, FASA-CR and CD-POC. These findings and instruments of FA and coercive-disruptive behavior enhance the current assessment of pediatric OCD. Targeting these common underlying factors can improve understanding, treatment planning, treatment monitoring and treatment efficacy of pediatric OCD in clinical practice.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"45 ","pages":"Article 100954"},"PeriodicalIF":1.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143935078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}