Braeden Hysuick-Weik, Blake A.E. Boehme, Holden J. Norrie, Eric D. Tessier, Gordon J.G. Asmundson
{"title":"Sensory over-responsivity in obsessive-compulsive disorder: A systematic review and meta-analysis of case control studies","authors":"Braeden Hysuick-Weik, Blake A.E. Boehme, Holden J. Norrie, Eric D. Tessier, Gordon J.G. Asmundson","doi":"10.1016/j.jocrd.2026.100994","DOIUrl":"10.1016/j.jocrd.2026.100994","url":null,"abstract":"<div><h3>Background</h3><div>Sensory over-responsivity (SOR) refers to distress experienced in response to ordinary sights, sounds, smells, and textures. This SOR has been found to be elevated in OCD. The current systematic review and meta-analysis assessed whether participants with OCD report higher SOR than healthy controls.</div></div><div><h3>Method</h3><div>Systematic searches were conducted in PsycINFO, PubMed, and Embase. The Newcastle-Ottawa Scale served as the tool for evaluating risk of bias. A random-effects meta-analysis was conducted using Hedges' <em>g</em> to estimate pooled effect sizes. Study heterogeneity was assessed using Cochran's <em>Q</em> and quantified with the <em>I</em><sup>2</sup> statistic. To evaluate the potential influence of unpublished or missing studies, Egger's regression was applied.</div></div><div><h3>Results</h3><div>A total of <em>k</em> = 6 studies (<em>N</em> = 376 OCD; <em>N</em> = 713 controls) met inclusion criteria. Participants with OCD exhibited significantly higher SOR compared to healthy controls (Hedges’ <em>g</em> = 1.73; 95 % CI [1.22, 2.24], <em>Z</em> = 6.62, <em>p</em> < .001; <em>I</em><sup>2</sup> = 76.2 %). An examination of the results for potential bias found no indication of missing or unpublished studies that might have influenced the findings. Risk of bias ratings showed the studies were of moderate to high quality.</div></div><div><h3>Discussion</h3><div>People with OCD show significantly higher SOR than healthy controls, suggesting that heightened sensitivity to external sensory stimuli may be relevant to OCD. Considerable heterogeneity, coupled with the small number of studies, raises some uncertainty about the generalizability of the results. Clinicians might consider SOR in case formulation. Further research is needed to gain a deeper understanding of SOR in other clinical populations.</div></div><div><h3>Registration</h3><div>CRD42024608769.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"48 ","pages":"Article 100994"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ariel Qi , John R. Best , Anna MacLellan , Gordan Andjelic , Boyee Lin , Cynthia Lu , Clara Westwell-Roper , S. Evelyn Stewart
{"title":"Family functioning impairment in pediatric obsessive-compulsive disorder and psychiatric outpatient controls","authors":"Ariel Qi , John R. Best , Anna MacLellan , Gordan Andjelic , Boyee Lin , Cynthia Lu , Clara Westwell-Roper , S. Evelyn Stewart","doi":"10.1016/j.jocrd.2025.100992","DOIUrl":"10.1016/j.jocrd.2025.100992","url":null,"abstract":"<div><div>Pediatric obsessive-compulsive disorder (OCD) imposes significant family functioning impairment (FFI) on household routines, socio-occupational activities, and caregiver emotional well-being. Low parental tolerance of one's child's distress (PTCD) predisposes to accommodation behaviors associated with poorer OCD outcomes. Knowledge is limited regarding whether family dysfunction is related to the burden of having a child with any mental illness, or whether it differs by psychiatric condition.</div></div><div><h3>Methods</h3><div>Our study compares FFI and PTCD outcomes between pediatric OCD and non-OCD disorders, and explores clinical correlates. Data were collected at tertiary outpatient child and adolescent psychiatry programs for OCD (<em>n</em> = 287) and five other specialty clinics (<em>n</em> = 1110). FFI and PTCD were measured by the Family Functioning Impairment Scale and Parental Tolerance of Child's Distress Scale, respectively.</div></div><div><h3>Results</h3><div>Multivariable linear regression modelling indicated greater FFI for youth with OCD in comparison to psychiatric controls (FFI difference = 3.5, <em>p</em> = .018), particularly regarding family routine disturbances (FFI difference = 2.4, <em>p</em> = .005). FFI was associated with traumatic incident history (FFI difference = 2.8, <em>p</em> = .012), financial struggles (FFI difference = 3.2, <em>p</em> = .002) and first-degree family history of developmental/psychiatric disorders (FFI difference = 4.6, <em>p</em> < .001). Results highlight the significant impacts of OCD on family functioning, with greater illness severity and household routine disruptions secondary to family symptom involvement as potential contributors. It also underscores the importance of family-inclusive OCD treatment strategies and tailored interdisciplinary supports to enhance family functioning.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"48 ","pages":"Article 100992"},"PeriodicalIF":1.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145840028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychometric properties of the action and acceptance questionnaire for trichotillomania in a clinical sample of patients with trichotillomania and skin picking disorder","authors":"Benjamin Hummelen , Filippa Brovold , Erna Moen , Karete Jacobsen Meland , Anniken Andersen , Diana Strand Johnsen , Toril Dammen , Douglas Woods , Torun Grøtte","doi":"10.1016/j.jocrd.2025.100972","DOIUrl":"10.1016/j.jocrd.2025.100972","url":null,"abstract":"<div><div>Self-report questionnaires can be valuable for evaluating treatment processes and outcomes in Acceptance and Commitment Therapy enhanced Behavioral Therapy (ACT-enhanced BT) for trichotillomania (TTM) and skin picking disorder (SPD). The Action and Acceptance Questionnaire for TTM (AAQ-4TTM) assesses experiential avoidance in individuals with TTM and can be easily adapted for patients with SPD by replacing references to “hair pulling” with “skin picking.” This study aims to evaluate the psychometric properties of the AAQ-4TTM, including factor structure, factor loadings, internal consistency, and construct validity, in a treatment-seeking sample of individuals with TTM or SPD. We expected no differences in factor structure and other psychometric properties across the two diagnostic groups. The study sample comprised 244 patients with a primary diagnosis of TTM (n = 144) or SPD (n = 100), all of whom were evaluated for ACT-enhanced BT. Contrary to our prediction, the exploratory factor analyses revealed different factor structures for the SPD group compared to the TTM group. While a two-factor structure emerged in the TTM group, a unidimensional structure was found in the SPD group. In TTM, the two factors were labeled “<em>Acceptance</em>” and “<em>Interference</em>”. The <em>Interference</em> factor showed stronger associations with measures of psychopathology than the <em>Acceptance</em> factor. The SPD factor, labeled “<em>Flexibility</em>”, showed the strongest correlation with self-reported skin-picking severity. Although the psychometric properties of the AAQ-4TTM were not optimal, the two factors identified in the TTM group seem to represent meaningful constructs within the ACT framework. In the SPD group, the AAQ-4SPD appears to function as a unidimensional scale, reflecting Psychological flexibility.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"47 ","pages":"Article 100972"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna M. White, Fiona C. Ball, Jonathan A. Teller, Katie H. Mangen, Kevin D. Wu
{"title":"Associations among fear of self, family acceptance, and scrupulosity symptoms in the LGBTQ+ community","authors":"Anna M. White, Fiona C. Ball, Jonathan A. Teller, Katie H. Mangen, Kevin D. Wu","doi":"10.1016/j.jocrd.2025.100981","DOIUrl":"10.1016/j.jocrd.2025.100981","url":null,"abstract":"<div><div>Extant research suggests that LGBTQ+ individuals may be especially susceptible to experiencing obsessive-compulsive (OC) symptoms within the <em>unacceptable thoughts</em> symptom dimension. The current study sought to replicate and extend these findings by examining whether LGBTQ+ individuals report greater unacceptable thoughts and scrupulosity symptoms (religious- and/or moral-based symptoms) than do non-LGBTQ+ individuals. To further understand these experiences among LGBTQ+ individuals, we also examined the relations among OC symptoms and factors we hypothesized to be uniquely relevant: religiosity, fear of self, and family acceptance of LGBTQ+ identity. MTurk participants completed a battery of questionnaires. Results indicated that LGBTQ+ participants reported significantly higher scrupulosity and unacceptable thoughts symptoms than did non-LGBTQ+ participants. Notably, LGBTQ+ participants also reported significantly higher scores on other OC symptom dimensions than did non-LGBTQ+ participants. LGBTQ+ identity was significantly related to scrupulosity symptoms when controlling for religiosity and fear of self. In the LGBTQ+ sample, family acceptance of LGBTQ+ identity moderated an association between religiosity and scrupulosity symptoms. These results suggest that identity, family acceptance, and religiosity are meaningfully associated with OC symptoms in LGBTQ+ individuals. This line of research remains relatively nascent but should be a focus of efforts to better understand and eventually mitigate OC symptoms in the LGBTQ+ community.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"47 ","pages":"Article 100981"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145227169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kaeo Wongbusarakum , Erica Schug , Tamerlane C. Visher , Kaitlyn Sulivan-Pascual , Megan Mirkis , Precia Rhee , Adam C. Frank
{"title":"Factors associated with delays in assessment and treatment of obsessive-compulsive disorder: A scoping review","authors":"Kaeo Wongbusarakum , Erica Schug , Tamerlane C. Visher , Kaitlyn Sulivan-Pascual , Megan Mirkis , Precia Rhee , Adam C. Frank","doi":"10.1016/j.jocrd.2025.100982","DOIUrl":"10.1016/j.jocrd.2025.100982","url":null,"abstract":"","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"47 ","pages":"Article 100982"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145424454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unpacking inferential confusion: A critical review of the inference-based approach to obsessive-compulsive disorder","authors":"Nicholas S. Myers, Jonathan S. Abramowitz","doi":"10.1016/j.jocrd.2025.100983","DOIUrl":"10.1016/j.jocrd.2025.100983","url":null,"abstract":"","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"47 ","pages":"Article 100983"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145528528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caitlin M. Pinciotti , Gregor Horvath , Matti Cervin
{"title":"Compulsions in trauma-exposed patients with obsessive-compulsive disorder: Differences in prevalence and impact on treatment response","authors":"Caitlin M. Pinciotti , Gregor Horvath , Matti Cervin","doi":"10.1016/j.jocrd.2025.100964","DOIUrl":"10.1016/j.jocrd.2025.100964","url":null,"abstract":"<div><div>The effectiveness of exposure and response prevention (ERP), a front-line treatment for obsessive-compulsive disorder (OCD), is contingent on reducing engagement in compulsions, though recent research has found that certain compulsions may be less amenable to ERP. Given the impact of trauma exposure on OCD compulsions, the present study sought to examine whether compulsion-specific differences in treatment response may be attributable to trauma exposure. Using a sample of 622 patients diagnosed with OCD receiving intensive treatment (39.7 % trauma-exposed), certain compulsions were found to be more prevalent among trauma-exposed patients and differentially impacted treatment effectiveness. Trauma-exposed patients were more likely to engage in reassurance, rumination, and hair pulling, and less likely to engage in self-assurance compulsions compared to non-trauma exposed patients. Interestingly, among trauma-exposed patients, engaging in self-assurance compulsions was associated with better treatment outcomes and engaging in reassurance compulsions was associated with worsened treatment outcomes. Findings converge with trauma-focused treatment approaches, wherein functional self-assurance is not only permitted but encouraged. Although historically any form of assurance in ERP is discouraged, clinicians treating trauma-exposed patients with OCD may consider leveraging engagement in non-compulsive self-assurance to increase self-efficacy and treatment motivation and challenge distorted trauma-related beliefs. Findings highlight the importance of considering with nuance the function of underlying behaviors.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"46 ","pages":"Article 100964"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144212580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ryan J. Jacoby , Dalton L. Klare , Caroline H. Armstrong , Susanne S. Hoeppner , Jennifer Lerner , Sabine Wilhelm
{"title":"Risk-aversion with both high and low ambiguity: Elevated OCD symptom severity and intolerance of uncertainty are associated with less risk-taking in an OCD patient sub-sample","authors":"Ryan J. Jacoby , Dalton L. Klare , Caroline H. Armstrong , Susanne S. Hoeppner , Jennifer Lerner , Sabine Wilhelm","doi":"10.1016/j.jocrd.2025.100955","DOIUrl":"10.1016/j.jocrd.2025.100955","url":null,"abstract":"<div><div>In clinical settings, patients with obsessive compulsive disorder (OCD) are generally risk-averse, especially in the context of uncertainty. However, the literature examining risk-taking in OCD is conflicting, and studies directly comparing risk-taking under conditions of high versus low ambiguity are scant. In the current study, 60 participants (30 OCD, 30 non-psychiatric controls) completed a modified version of the Balloon Analogue Risk Task (BART) in which they “pumped” a virtual balloon and earned five cents for each pump; however, if the balloon popped, they lost the money accumulated in that round. The task had two levels of ambiguity: the risk level of each balloon (i.e., likelihood of it exploding) was either visually displayed (low ambiguity) or unknown (high ambiguity). The outcome was the average number of pumps for balloons that did not explode, with higher scores indicating more risk-taking. There was a main effect of ambiguity, such that participants took more risks on the low ambiguity BART compared to the high ambiguity version. Contrary to hypotheses, there was no ambiguity level x diagnostic group interaction. Within the OCD group, however, intolerance of uncertainty, OCD symptom severity, trait anxiety, and depression severity were negatively associated with risk-taking. Without a clinical control group, we're unable to determine specificity of these effects to OCD. The within-subjects design may have contributed to carryover effects. Findings underscore the importance of symptom dimensional measurement beyond mere presence or absence of diagnosis when predicting risk-aversion in OCD.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"46 ","pages":"Article 100955"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144254515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A cognitive intervention for negative beliefs about losing control: impact on other cognitive domains and OCD symptoms","authors":"Andrea Sandstrom, Adam S. Radomsky","doi":"10.1016/j.jocrd.2025.100966","DOIUrl":"10.1016/j.jocrd.2025.100966","url":null,"abstract":"<div><h3>Purpose</h3><div>Beliefs about losing control have been proposed as a novel cognitive domain in OCD. Despite increasing evidence that links these beliefs with OCD symptoms, it is unclear whether interventions targeting beliefs about losing control lead to symptom improvement. This study sought to develop and test the impact of a brief cognitive intervention for beliefs about losing control on OCD-relevant appraisals and symptoms in a sub-clinical OCD sample.</div></div><div><h3>Methods</h3><div>A total of 35 sub-clinical participants were recruited based on self-reported OCD symptoms and beliefs about losing control, and randomly assigned to receive a 1-h CBT session targeting beliefs about losing control (intervention) or sleep hygiene (control). Beliefs about losing control, and OCD symptom were assessed at baseline and one week after the intervention using self-report questionnaires. Appraisals of losing control and OCD-relevant appraisals were also assessed using daily monitoring forms during the two-week intervention period.</div></div><div><h3>Results</h3><div>There was a significant interaction between condition and time on appraisals of losing control and OCD-relevant appraisals measured by the daily monitoring forms, with those in the intervention condition showing greater reductions from baseline to follow-up compared to those in control condition. There were no significant interaction effects on beliefs about losing control or OCD symptoms measured using standardized self-report questionnaires.</div></div><div><h3>Conclusions</h3><div>These results suggest that incorporating strategies targeting beliefs about losing control into CBT for OCD may be warranted, however more time and/or sessions is/are likely required to achieve broader symptom improvement.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"46 ","pages":"Article 100966"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144280647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olivia C. Bishop , Brooke Hiscock , Quinn Morris , Chelsea Lahey , Charlotte Corran , Sandra Krause , Jonathan M. Fawcett , Emily J. Fawcett
{"title":"The prevalence of aggressive obsessions in youth with obsessive-compulsive disorder: A meta-analysis","authors":"Olivia C. Bishop , Brooke Hiscock , Quinn Morris , Chelsea Lahey , Charlotte Corran , Sandra Krause , Jonathan M. Fawcett , Emily J. Fawcett","doi":"10.1016/j.jocrd.2025.100963","DOIUrl":"10.1016/j.jocrd.2025.100963","url":null,"abstract":"<div><div>Despite obsessive-compulsive disorder (OCD) being a recognizable psychiatric disorder, certain presentations of OCD are still highly stigmatized and misidentified by healthcare professionals. Namely, aggressive obsessions, which include ego-dystonic, intrusive thoughts and fears of accidentally or intentionally harming the self or others, are vastly under researched. With current prevalence estimates for aggressive obsessions in pediatric OCD ranging anywhere from 30.8 % to 86 %, the primary aim of the current meta-analysis was to provide the first meta-analytic estimate of the worldwide prevalence of aggressive obsessions among youth with OCD. A secondary goal of this study was to quantify sources of heterogeneity that contribute to the variability in prevalence estimates to date. A systematic review was conducted in Covidence using the following online databases: PsycINFO, PubMed, and CINAHL. Of the 4218 articles imported and screened, 831 received a full-text review, with 27 studies (<em>N</em> = 3428) ultimately coded. Using a random-effects model, the aggregate lifetime prevalence rate of aggressive obsessions was found to be 65.1 % <em>CI</em><sub><em>95 %</em></sub> [57.3 %, 72.2 %], with prediction intervals ranging from 43.9 % to 81.7 %, and a current prevalence rate of 61.9 % <em>CI</em><sub><em>95 %</em></sub> [56.4 %, 67.0 %], with prediction intervals ranging from 37.0 % to 81.8 %. The presence of comorbidities and the type of diagnostic measure utilized were found to be significant moderators for current estimates. With over half of youth experiencing aggressive obsessions in their lifetime, continuing education is required for healthcare professionals to be able to identify and properly treat this common, but often overlooked, symptom dimension.</div></div>","PeriodicalId":48902,"journal":{"name":"Journal of Obsessive-Compulsive and Related Disorders","volume":"46 ","pages":"Article 100963"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144205436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}