Archivos Espanoles De Urologia最新文献

{"title":"Nursing Management for the Prevention of Urinary Catheter-Associated Urinary Tract Infections in the Emergency Intensive Care Unit: A Retrospective Study.","authors":"Yanbin Li, Xin Chen, Daqi Chen","doi":"10.56434/j.arch.esp.urol.20257810.184","DOIUrl":"10.56434/j.arch.esp.urol.20257810.184","url":null,"abstract":"<p><strong>Objective: </strong>Catheter-associated urinary tract infection (CAUTI) is a common type of hospital-acquired infection in the emergency intensive care unit (EICU). The aim of this study was to explore effective nursing management programs to reduce the incidence of CAUTI in patients with EICU.</p><p><strong>Methods: </strong>This retrospective study collected the clinical data of critically ill patients from the Department of Emergency Medicine of Soochow University in China from January 2024 to December 2024. Patients admitted from January to June 2024 were treated in the usual care group, and patients admitted from July to December 2024 were treated in the CAUTI prevention care group. The monthly incidence of CAUTI, the duration of urinary catheter indwelling, the duration of bladder irritation symptoms, the number of days of hospitalisation and the adverse reaction rate of patients in the two time periods were compared.</p><p><strong>Results: </strong>A total of 833 patients were admitted to the EICU for observation, and they were divided into the usual care group (n = 427) and the CAUTI prevention care group (n = 406). Ninety-seven patients developed CAUTI, with an overall incidence rate of 11.64%. Among them, 64 cases (14.99%) of CAUTI occurred in the conventional nursing group, which was higher than that in the CAUTI prevention care group (33 cases, 8.13%), and the difference was statistically significant (<i>p</i> < 0.05). The duration of urinary catheterisation, duration of bladder irritation, length of hospital stay and incidence of adverse reactions in patients with CAUTI in the CAUTI prevention care group were lower than those in the usual care group (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>Reasonable nursing management program is related to a low incidence of CAUTI in EICU and has a certain effect on its prevention.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 10","pages":"1410-1417"},"PeriodicalIF":0.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145907101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Symptom Management Theory-Based Nursing Treatment Model for Patients Undergoing Radical Prostatectomy: A Single-Center, Retrospective Experience.","authors":"Hui Xu, Guanghui Zhong, Ruimin He","doi":"10.56434/j.arch.esp.urol.20257810.192","DOIUrl":"10.56434/j.arch.esp.urol.20257810.192","url":null,"abstract":"<p><strong>Background and aims: </strong>Radical prostatectomy is the key for localised prostate cancer, but postoperative urinary incontinence and chronic pain impair outcomes. Enhancing perioperative care improves prognosis. This single-centre retrospective study evaluated a symptom management theory-based nursing model for radical prostatectomy patients.</p><p><strong>Methods: </strong>A total of 165 patients were divided into the control (routine care, n = 75) and observation (symptom management nursing, n = 90) groups. After propensity score matching (PSM), 67 patients per group were analysed. Outcomes (pain: Visual Analogue Scale (VAS); Urinary incontinence: International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UISF); Negative emotions: Self-Rating Anxiety Scale (SAS)/Self-Rating Depression Scale (SDS); Quality of life: Functional Assessment of Cancer Therapy-Prostate (FACT-P)) were assessed before treatment, end of 2-week treatment and 1 month post-treatment. Three-month postoperative complications were compared.</p><p><strong>Results: </strong>At end of treatment and 1-month post-treatment, the observation group had lower VAS, ICIQ-UISF, SAS and SDS scores (all <i>p</i> < 0.05), higher FACT-P scores (all dimensions, <i>p</i> < 0.05) and lower urinary incontinence incidence (<i>p</i> < 0.05). The 3-month complication rate was 7.46% (5/67) vs 19.40% (13/67) in the control (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>Symptom management-based nursing alleviates pain, reduces urinary incontinence, relieves negative emotions, improves the quality of life and lowers complications, with clinical value for postoperative rehabilitation.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 10","pages":"1476-1484"},"PeriodicalIF":0.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145907127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Urinary Continence, Complications, and Urodynamic Characteristics Following Orthotopic Ileocaecal Neobladder Reconstruction: A Preliminary Study on Safety and Feasibility.","authors":"Qiang Fu, Fengqi Yan, Zhenye Sun, Zhen Yao, Geng Zhang","doi":"10.56434/j.arch.esp.urol.20257810.194","DOIUrl":"10.56434/j.arch.esp.urol.20257810.194","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the postoperative recovery of urinary continence, complications, metabolic changes and urodynamic parameters in patients with bladder cancer undergoing radical cystectomy combined with orthotopic ileocaecal neobladder reconstruction and to explore the safety and functional feasibility of this surgical approach.</p><p><strong>Methods: </strong>A retrospective analysis was performed on 45 bladder cancer patients who underwent radical cystectomy with orthotopic ileocaecal neobladder reconstruction at our hospital between January 2020 and January 2025. All patients received standardised postoperative follow-up, including urodynamic evaluations at 6 and 12 months, and rehabilitation training such as pelvic floor exercises, abdominal pressure-assisted voiding, and bladder sensation training. Clinical outcomes were assessed by comparing urinary continence, complications, biochemical parameters, and urodynamic indices at different postoperative time points.</p><p><strong>Results: </strong>At 3 months postoperatively, urinary incontinence (daytime and nighttime) was higher than at 6 months, indicating gradual improvement over time (<i>p</i> < 0.05). Early complications, mainly urine leakage and infections, were relatively common within 3 months but decreased thereafter, with few patients experiencing enterocutaneous fistula, urinary fistula, or urinary stones (<i>p</i> > 0.05). Postoperative haemoglobin and serum chloride decreased significantly (<i>p</i> < 0.05), while other biochemical parameters remained largely unchanged, except for an increase in blood urea nitrogen. Urodynamic assessments showed that by 12 months, neobladder maximum capacity and urinary flow rate increased significantly (<i>p</i> < 0.05), storage-phase bladder pressure decreased below urethral closure pressure (<i>p</i> < 0.05), voiding-phase pressures were unchanged (<i>p</i> > 0.05), and post-void residual volume was reduced (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>Orthotopic ileocaecal neobladder reconstruction after radical cystectomy is a safe and feasible urinary diversion. With standardised rehabilitation and follow-up, patients achieve satisfactory continence and stable metabolic and bladder function. However, long-term outcomes require validation in larger studies.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 10","pages":"1493-1500"},"PeriodicalIF":0.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145907025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeted Regulation of Mitosis through Eg5 Protein Enhances Radiosensitivity of Renal Cell Carcinoma.","authors":"Kejia Zhu, Changlin Mao, Delong Zhao, Armin Ghavamian, Yong Guan, Sentai Ding","doi":"10.56434/j.arch.esp.urol.20257810.185","DOIUrl":"10.56434/j.arch.esp.urol.20257810.185","url":null,"abstract":"<p><strong>Background: </strong>Renal cell carcinoma (RCC) is a radiation-resistant tumor. Eg5, a spindle motor protein, plays a crucial role in centrosome separation and bipolar spindle formation during mitosis. We explored whether Eg5 is an important therapeutic target for treating RCC.</p><p><strong>Methods: </strong>We selected radiation-resistant 786-O renal carcinoma cells and divided them into four groups: Control, 10 Gy irradiation, Eg5 inhibitor, and 10 Gy + Eg5 inhibitor. The proliferative ability of the tumor cells was assessed using the cell counting kit-8 assay; A transwell assay was employed to evaluate their invasive capacity. A clonogenic assay was performed to assess clonogenic survival. We divided the 786-O renal carcinoma cells into 10 Gy irradiation and 10 Gy + Eg5 inhibitor groups. Flow cytometry, cell cycle analysis, polymerase chain reaction (PCR), and western blotting were conducted to compare radiosensitivity between the two groups and to investigate potential underlying mechanisms.</p><p><strong>Results: </strong>The levels of cell proliferation, clonogenic survival, and migration in the 10 Gy + Eg5 inhibitor group (0.395 ± 0.007, 119.3 ± 7.513, 24.33 ± 2.333, respectively) were significantly lower than those in the control (0.772 ± 0.005, 294.3 ± 10.710, 83.00 ± 3.786, respectively) and 10 Gy groups (0.667 ± 0.006, 211.7 ± 9.528, 54.33 ± 2.728, respectively) (<i>p</i> < 0.05). Flow cytometry showed that the level of apoptosis in the 10 Gy + Eg5 inhibitor group (16.87 ± 2.476, 17.0%) was significantly higher than in the 10 Gy group (6.319 ± 0.380, 6.0%) (<i>p</i> < 0.05). Flow cytometry analysis further revealed that the proportion of cells in the G1 phase in the 10 Gy + Eg5 inhibitor group (10.037 ± 1.434) was lower than in the 10 Gy group (24.327 ± 2.252) (<i>p</i> < 0.05). PCR results showed that the messenger ribonucleic acid (mRNA) levels of <i>H2AX</i>, <i>TP53BP1</i>, <i>XRCC1</i>, and <i>CDKN1A</i> in the 10 Gy + Eg5 inhibitor group were significantly higher than those in the 10 Gy group (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>Eg5 inhibitors specifically bind to the Eg5 protein and disrupt mitosis, thereby improving the radiosensitivity of RCC by regulating the cell cycle. An Eg5 inhibitor combined with radiotherapy may represent an effective adjuvant therapy for RCC.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 10","pages":"1418-1428"},"PeriodicalIF":0.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145907111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Values of Serum Matrix Metalloproteinase-9 and Nuclear Matrix Protein 22 for Bladder Cancer.","authors":"Li Chen, Junhui He","doi":"10.56434/j.arch.esp.urol.20257809.162","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257809.162","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate the diagnostic value of serum matrix metalloproteinase-9 (MMP-9) and nuclear matrix protein 22 (NMP22) in patients with bladder cancer.</p><p><strong>Methods: </strong>Patients pathologically diagnosed with bladder cancer between January 2023 and January 2024 were included as the experimental group, while healthy individuals undergoing routine physical examinations during the same period comprised the control group. Serum MMP-9 and NMP22 levels were measured via enzyme-linked immunosorbent assay. Diagnostic performance was assessed using receiver operating characteristic curves, and multivariate logistic regression was performed to determine their ability to independently predict tumor-node-metastasis (TNM) stage.</p><p><strong>Results: </strong>Serum MMP-9 and NMP22 levels were significantly higher in bladder cancer patients compared to healthy controls (<i>p</i> < 0.001). Patients at the T stage showed significantly elevated levels compared to those at the N and M stages (<i>p</i> < 0.001). The areas under the curves for MMP-9, NMP22, and their combination were 0.786 (95% confidence interval (CI): 0.714-0.857), 0.785 (95% CI: 0.714-0.857), and 0.793 (95% CI: 0.725-0.862), respectively, with corresponding sensitivities of 70.00%, 72.00%, and 75.00%, and specificities of 80.00%, 78.00%, and 85.00%. Hematuria (odds ratio (OR): 3.42, 95% CI: 1.89-6.18), frequent urination (OR: 2.44, 95% CI: 1.41-4.22), urinary urgency (OR: 2.18, 95% CI: 1.19-3.99), MMP-9 (OR: 1.01, 95% CI: 1.004-1.016), and NMP22 (OR: 0.98, 95% CI: 0.97-0.99) were identified as independent predictors of TNM stage (<i>p</i> < 0.05). The Cancer Genome Atlas (TCGA) data further confirmed elevated MMP-9 messenger RNA (mRNA) expression in tumor tissues versus adjacent normal tissues (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>Serum MMP-9 and NMP22 levels are significantly elevated in bladder cancer and correlate with TNM stage. Combined detection may improve diagnostic accuracy and clinical utility in bladder cancer diagnosis.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 9","pages":"1254-1260"},"PeriodicalIF":0.9,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protective and Therapeutic Effects of Apilarnil on Cisplatin-Induced Gonadal Toxicity in Rats.","authors":"Emre Can Akınsal, Sibel Silici, Züleyha Doğanyiğit, Banu Yücel, Ünsal Baş, Numan Baydilli","doi":"10.56434/j.arch.esp.urol.20257809.154","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257809.154","url":null,"abstract":"<p><strong>Background: </strong>Cisplatin (CP) is an effective chemotherapeutic agent. However, its clinical application is limited by its notable gonadotoxic and systemic side effects. Apilarnil, a biologically active product of drone larva, possesses antioxidant, anti-inflammatory and androgenic properties, which suggests its potential protective effects against chemotherapy-induced toxicity. This study aimed to investigate the protective and therapeutic effects of different doses of apilarnil on CP-induced gonadal toxicity and systemic biochemical changes in a rat model.</p><p><strong>Methods: </strong>A total of 64 adult male Wistar rats were randomly assigned to eight experimental groups, including the control, CP-treated, apilarnil-treated (50 and 100 mg/kg) and combined CP-apilarnil treatment groups. Treatments were administered via orogastric gavage or intraperitoneal injection. Testicular and epididymal weights, epididymal sperm concentration and motility, haematological and biochemical parameters and histopathological changes were evaluated.</p><p><strong>Results: </strong>CP administration considerably decreased testis and epididymis weights, sperm concentration and motility while altering haematological indices (mean corpuscular volume, lymphocytes and neutrophils), elevating serum glucose, triglycerides, cholesterol, liver enzyme levels and reducing testosterone levels. Apilarnil treatment, particularly when administered prior to CP exposure, ameliorated these adverse effects by improving sperm parameters, normalising blood indices, modulating biochemical markers and enhancing histological preservation of seminiferous tubules.</p><p><strong>Conclusions: </strong>Apilarnil exhibits promising protective effects against CP-induced gonadal toxicity and systemic damage. These findings support further investigation of apilarnil as an adjunctive agent to mitigate chemotherapy-associated side effects.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 9","pages":"1178-1187"},"PeriodicalIF":0.9,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolomics in Prostate Cancer: A Minimally Invasive Method Using Urine after Prostatic Massage to Predict Gleason Grade.","authors":"Jorge Panach-Navarrete, Vannina González-Marrachelli, José Manuel Morales-Tatay, Francisco García-Morata, María Ángeles Sales-Maicas, Daniel Monleón-Salvado, José María Martínez-Jabaloyas","doi":"10.56434/j.arch.esp.urol.20257809.148","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257809.148","url":null,"abstract":"<p><strong>Background: </strong>In this study, biomarkers that can predict prostate cancer with a Gleason grade of 8 or higher were explored through nuclear magnetic resonance (NMR).</p><p><strong>Methods: </strong>Patients scheduled for transrectal prostate biopsy were enrolled, and urine samples were collected after prostate massage. Patients with cancer were categorised as having Gleason grades of 6-7 or ≥8. All spectra were acquired using a Bruker Avance III DRX 600 spectrometer. For statistical analysis, univariate and multivariate analyses were conducted using metabolites and clinical variables, and the presence of tumours with Gleason grades of ≥8 was predicted.</p><p><strong>Results: </strong>Data were obtained from 107 patients with prostate cancer: 73 (68.2%) with Gleason grades of 6-7 and 34 (31.8%) with Gleason grades of ≥8. A predictive model incorporating the 29 most significant metabolites identified through partial least squares-discriminant analysis was established. Suspicious digital rectal examination (DRE) results were considered. The model predicted a Gleason grade of ≥8, demonstrating an area under the curve of 0.92, sensitivity of 82%, specificity of 92%, positive predictive value of 84% and negative predictive value of 90%. Metabolites associated with amino acid metabolism and glycolysis were prominent in this model.</p><p><strong>Conclusions: </strong>Our study demonstrates that a model combining urinary metabolites with clinical data, specifically DRE findings, can effectively stratify risk in patients with biopsy-confirmed prostate cancer according to Gleason grade. Metabolites linked to glycolysis and amino acid metabolism were particularly relevant. This minimally invasive approach may assist clinical decision-making, although validation in larger multi-centre cohorts is required to confirm its robustness and generalisability.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 9","pages":"1132-1142"},"PeriodicalIF":0.9,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urolithiasis Due to Adenine Phosphoribosyl Transferase (APRT) Deficiency: A Case Report and Practical Recommendations in Children.","authors":"Khaled Lajmi, Kahena Bouzid, Najoua Blaiech, Sameh Mabrouk, Selsabil Nouir, Nahla Kechiche","doi":"10.56434/j.arch.esp.urol.20257809.171","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257809.171","url":null,"abstract":"<p><strong>Background: </strong>The rare metabolic disease, adenine phosphoribosyl transferase (APRT) deficiency, is asymptomatic in many cases until it is discovered in terminal renal failure. The most frequent complication is 2,8-dihydroxyadenine (2,8-DHA) urolithiasis. Stones, which are frequently bilateral and recurrent, appear in childhood in one-third of cases.</p><p><strong>Case report: </strong>An 8-year-old girl presented with urinary tract infection and coralliform urolithiasis in the right kidney. Initial radiological examination showed emphysematous pyelonephritis stage 1 due to obstructive lithiasis. Stone analysis helped confirm the diagnosis of APRT deficiency.</p><p><strong>Discussion: </strong>The diagnostic difficulties, clinical manifestations, and the impact of early detection and management on preventing stone recurrence and complication were discussed. The therapeutic strategies available, including dietary modifications and allopurinol therapy, were reviewed.</p><p><strong>Conclusions: </strong>Early intervention with therapeutic and dietetic measures could preserve the normal renal function of the young patient.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 9","pages":"1323-1328"},"PeriodicalIF":0.9,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Focal Therapy for Prostate Cancer: Available Technologies, Patient Selection, Follow-Up Protocols and Reported Outcomes.","authors":"Julio Pow-Sang, Gustavo Ruschi Bechara","doi":"10.56434/j.arch.esp.urol.20257809.147","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257809.147","url":null,"abstract":"<p><p>The first description of focal therapy (FT) for prostate cancer was by Gary Onik when he described the use of hemigland cryoablation. Currently, focal therapy is performed using different energy modalities: (1) Cryotherapy, (2) irreversible electroporation, (3) high-intensity focused ultrasound, (4) transurethral ultrasound ablation, (5) focal laser therapy, (6) bipolar radiofrequency ablation and (7) photodynamic therapy. Intermediate-risk prostate cancer with an index lesion seen on prostate magnetic resonance imaging, with negative or low-grade cancer on systematic biopsies is appropriate candidate for focal therapy. Currently, most follow-up protocols include prostate-specific antigen (PSA) measurement every three months during the first year and every six months thereafter, conducting multiparametric magnetic resonance imaging (mpMRI) scans at six months, twelve months, and then annually, as well as performing targeted biopsies of the ablation zone along with systematic biopsies between six to twelve months post-treatment. In general, FT rarely results in significant morbidity and appears to have a minimal effect on quality of life, however long-term oncological outcomes require further assessment. The heterogeneity in technologies, patient selection criteria, follow-up protocols and lack of high-level evidence for focal therapy present the biggest challenges in recommending this treatment modality as a standard management option for selecting patients. The aim of this article is to discuss the challenges surrounding patient selection and to review the different focal therapy modalities and follow-up strategies after treatment.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 9","pages":"1124-1131"},"PeriodicalIF":0.9,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145669983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Body Image Perception in Patients Who Have Undergone Endoscopic Surgery for Kidney Stones: A Prospective Study.","authors":"Erdogan Aglamis, Cavit Ceylan, Kadir Yildirim, Sedat Tastemur, Emre Uzun","doi":"10.56434/j.arch.esp.urol.20257809.150","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257809.150","url":null,"abstract":"<p><strong>Background: </strong>The body image perception (BIP) of patients may deteriorate after surgery. Our study aims to evaluate the BIP of patients who underwent retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotomy (PCNL) because of kidney stones.</p><p><strong>Methods: </strong>A total of 158 patients, including 46 patients who underwent PCNL, 57 patients who underwent RIRS and 55 patients in a healthy control group, were included in this prospective study. The BIP of patients was evaluated by using the Body Dysmorphic Disorder Scale (BDDS) questionnaire. BDDS was administered to patients during the preoperative period and in the first and third postoperative months. The BDDS scores of patients were compared amongst the PCNL, RIRS and control groups. One-way analysis of variance (ANOVA) was employed to compare the means of variables across the three patient groups.</p><p><strong>Results: </strong>The mean BDDS score in the PCNL group (n = 46) was significantly higher than that in the RIRS (n = 57) and control groups (n = 55) in the first postoperative month (<i>p</i> = 0.008 and 0.008). No significant difference was found between the mean BDDS scores of patients in the RIRS and control groups in the first postoperative month (<i>p</i> = 1.000). No significant difference was found amongst the mean BDDS scores of patients in the PCNL, RIRS and control groups in the third postoperative month (<i>p</i> = 0.725). A positive correlation was found between the educational levels and BDDS scores of patients (<i>p</i> = 0.000, r = 0.529), whereas a negative correlation was found between age and BDDS score (<i>p</i> = 0.030, r = -0.320).</p><p><strong>Conclusions: </strong>No deterioration in BIP was found in patients who underwent RIRS. In patients who underwent PCNL, negative BIP was observed in the first postoperative month and improved by the third postoperative month, reaching levels similar to those in the control and RIRS groups. RIRS and PCNL are reliable surgical methods in terms of postoperative BIP.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 9","pages":"1149-1156"},"PeriodicalIF":0.9,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}