Jin Luo, Nan Xie, Jingxi Wang, Xuemei An, Tao Yang
{"title":"Effect of Nurse-Led Clean Intermittent Catheterization Synchronous Health Education on Patients with Urinary Dysfunction after Spinal Cord Injury.","authors":"Jin Luo, Nan Xie, Jingxi Wang, Xuemei An, Tao Yang","doi":"10.56434/j.arch.esp.urol.20247707.113","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20247707.113","url":null,"abstract":"<p><strong>Objective: </strong>Spinal cord injury (SCI) severely affects motor, sensory, reflex, and other functions, impacting 250,000 to 500,000 individuals globally each year. Bladder voiding dysfunction, a prevalent and serious complication of SCI, results in significant morbidity and reduced quality of life. This study examines the impact of nurse-led clean intermittent catheterization combined with synchronous health education for family members on improving compliance in patients with SCI and bladder voiding dysfunction.</p><p><strong>Methods: </strong>Eighty-four patients with urinary dysfunction post-SCI treated in our hospital from January 2023 to January 2024 were selected. Family members were assigned to a control group (n = 40) or an observation group (n = 44) based on their participation in nurse-led health education. Urinary tract management proficiency, satisfaction, compliance, and complications were observed and statistically analyzed in both groups on the 30th day after self-initiated intermittent catheterization.</p><p><strong>Results: </strong>By the 30th day, the observation group exhibited significantly higher cognitive scores in urinary tract management than the control group (<i>p</i> < 0.001). Additionally, the observation group showed greater compliance in daily water intake (<i>p</i> = 0.018), proper timing (<i>p</i> = 0.018), and correct bladder function training (<i>p</i> = 0.004). The incidence of urinary tract infections was lower in the observation group (<i>p</i> = 0.018). Patient satisfaction in the observation group also exceeded that of the control group in all measured aspects and total scores (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>Nurse-led synchronous health education for family members during clean intermittent catheterization significantly enhances patient compliance, reduces complications, and improves patient satisfaction.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"77 7","pages":"811-817"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Efficacy of Electroacupuncture at Sacral Four Points Combined with Moxibustion at Abdominal Three Points for Treating Post-Stroke Urinary Incontinence: Observations on Urodynamics, Quality of Life, and Safety.","authors":"Miaomiao Yi, Wei Shen, Yuan Wei","doi":"10.56434/j.arch.esp.urol.20247707.102","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20247707.102","url":null,"abstract":"<p><strong>Background: </strong>Urinary incontinence is a common complication following a stroke. No specific drugs are available in Western medicine, and surgical treatment is highly traumatic, limiting its clinical application. This study aimed to observe the clinical efficacy of electroacupuncture at the \"Sacral Four Points\" combined with moxibustion at the \"Abdominal Three Points\" on post-stroke urinary incontinence, exploring its impact on urodynamics and quality of life.</p><p><strong>Methods: </strong>Patients with post-stroke urinary incontinence treated at our Hospital from January 2021 to December 2023 were recruited. The study included 117 patients: 57 in the electroacupuncture group and 60 in the combined group. Urodynamic parameters were measured, and scores from the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) and the Incontinence Quality of Life Questionnaire (I-QOL) were recorded before, and after the first and third courses of treatment. Clinical efficacy and adverse reactions were evaluated post-treatment.</p><p><strong>Results: </strong>The study found no significant differences in clinical characteristics between the groups (<i>p</i> > 0.05), providing a baseline for comparison. Both groups showed substantial decreases in leakage volume after one course of treatment (<i>p</i> < 0.05), with a reduction in the ICIQ-UI SF score (<i>p</i> < 0.05) and an increase in the I-QOL score (<i>p</i> < 0.05). After three courses of treatment, the leakage volume of patients in both groups significantly decreased (<i>p</i> < 0.05), the ICIQ-UI SF score decreased (<i>p</i> < 0.05), and the I-QOL score increased (<i>p</i> < 0.05). The combined group showed a lower leakage volume compared to the electroacupuncture group (<i>p</i> < 0.05), with lower ICIQ-UI SF scores (<i>p</i> = 0.027) and higher I-QOL scores (<i>p</i> = 0.048). Importantly, the total effective rate was significantly higher in the combined group (88.33% vs 64.91%, <i>p</i> = 0.037), demonstrating the safety and efficacy of the treatment.</p><p><strong>Conclusions: </strong>Electroacupuncture at the \"Sacral Four Points\" combined with moxibustion at the \"Abdominal Three Points\" improves the clinical symptoms and enhances the quality of life for patients with post-stroke urinary incontinence, showing superior results compared to electroacupuncture alone.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"77 7","pages":"732-738"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Müslüm Ergün, Süleyman Sağır, Osman Akyüz, Ramazan Yavuz Akman
{"title":"Evolving Approach in Nephron-Sparing Surgery: Has Anything Changed from Open Surgery to Laparoscopy?","authors":"Müslüm Ergün, Süleyman Sağır, Osman Akyüz, Ramazan Yavuz Akman","doi":"10.56434/j.arch.esp.urol.20247707.101","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20247707.101","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to provide valuable insights into the comparative efficacy of different surgical approaches for nephron-sparing surgery (NSS) and contribute to the existing literature in this field.</p><p><strong>Materials and methods: </strong>This study included patients who underwent NSS for small renal masses between January 2016 and March 2024. A total of 97 patients (41 in the open approach group, 56 in the laparoscopic approach group) with demographic, radiological, intraoperative, renal functional, and oncological follow-up data were included. Three different anatomical scoring systems (R.E.N.A.L. nephrometry score, PADUA score and C-index) were utilised to assess tumour location and estimate proximity to the hilum and collecting system.</p><p><strong>Results: </strong>In the open nephron-sparing surgery (ONSS) and laparoscopic nephron-sparing surgery (LNSS) groups, the mean kidney tumour diameters (SD) were 5.20 ± 2.30 and 4.90 ± 2.10, which were similar in both surgical method groups (<i>p</i> = 0.061). However, tumours treated with ONSS had significantly more adverse morphometric features (<i>p</i> < 0.05). For ONSS and LNSS groups, the mean R.E.N.A.L. nephrometry scores (SD) were 6.15 ± 2.04 and 5.2 ± 1.4 (<i>p</i> = 0.032), respectively; The mean PADUA scores (SD) were 7.46 ± 1.14 and 6.8 ± 1.0 (<i>p</i> = 0.049), respectively; And the mean C-index (SD) scores were 1.39 ± 0.4 and 1.37 ± 0.5 (<i>p</i> = 0.062), respectively. No significant differences were found in the mean tumour diameter (cm) (Inter Quantile Range (IQR)) distribution of both groups (<i>p</i> = 0.058). Despite the slight increase in transfusion rate in the LNSS group, estimated blood loss (EBL), transfusion rates, and length of hospital stay were similar in both groups.</p><p><strong>Conclusions: </strong>Although LNSS does not appear superior in terms of intraoperative blood loss, length of hospital stay and transfusion rate, it provides comparable long-term outcomes to ONSS. Our study suggests that when matched with nephrometry scores, LNSS can achieve similar outcomes to ONSS.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"77 7","pages":"726-731"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Weiyang Zhang, Qingyuan Liu, Jindong Zhang, Delin Wang
{"title":"FBXO45 Knockdown Restrains the Progression of Bladder Cancer via the ERK/Cyclin D1/CDK4 Pathway.","authors":"Weiyang Zhang, Qingyuan Liu, Jindong Zhang, Delin Wang","doi":"10.56434/j.arch.esp.urol.20247707.111","DOIUrl":"10.56434/j.arch.esp.urol.20247707.111","url":null,"abstract":"<p><strong>Backgrounds: </strong>F-box protein 45 (<i>FBXO45</i>) has been implicated in the progression of several diseases. Whether <i>FBXO45</i> is involved in the development of bladder cancer remains unclear. Thus, this study focused on the effect of <i>FBXO45</i> on the malignant progression of bladder cancer cells.</p><p><strong>Methods: </strong><i>FBXO45</i> small-interference fragment was transfected into RT4 and 5637 cells by liposome-mediated transfection, and the knockdown efficiency of <i>FBXO45</i> was verified by Western blot assay. The growth rate between <i>FBXO45</i> knockdown cell lines and control cell lines was compared by counting kit 8 and plate cloning experiments. The motility of bladder cancer cells was observed via the Transwell test and Wound healing test. The effects of <i>FBXO45</i> silencing on apoptosis and cell division were confirmed by flow cytometry. Western blot assay was performed to determine the function of <i>FBXO45</i> knockdown on key proteins of cell apoptosis and the ERK/Cyclin D1/CDK4 pathway.</p><p><strong>Results: </strong>After <i>FBXO45</i> knockdown, the proliferation of bladder cancer cells was blocked (<i>p</i> < 0.01), and the migration and invasion abilities were reduced (<i>p</i> < 0.01). <i>FBXO45</i> knockdown reduced the number of S-phase cells (RT4, <i>p</i> < 0.01; 5637, <i>p</i> < 0.05) and enhanced the apoptotic rate (<i>p</i> < 0.01). <i>FBXO45</i> knockdown decreased the levels of p-ERK1/2, CDK4 and Cyclin D1 (<i>p</i> < 0.01).</p><p><strong>Conclusions: </strong>This study revealed that <i>FBXO45</i> plays a carcinogenic role in bladder cancer via the ERK/Cyclin D1/CDK4 pathway, which provides a reference for the clinical treatment of patients with bladder cancer.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"77 7","pages":"796-804"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guglielmo Mantica, Mikołaj Frankiewicz, Wesley Verla, Marjan Waterloos, Malte W Vetterlein, André Van der Merwe, David Ralph, Andrea Cocci, On Behalf Of Trauma And Reconstructive Urology Working Party Of The European Association Of Urology Young Academic Urologists And Eau Section Of Genitourinary Reconstructive Surgeons
{"title":"Genital Art in the 21st Century: Piercings and Tattoos. The EAU YAU Reconstructive Urology Working Party Point of View.","authors":"Guglielmo Mantica, Mikołaj Frankiewicz, Wesley Verla, Marjan Waterloos, Malte W Vetterlein, André Van der Merwe, David Ralph, Andrea Cocci, On Behalf Of Trauma And Reconstructive Urology Working Party Of The European Association Of Urology Young Academic Urologists And Eau Section Of Genitourinary Reconstructive Surgeons","doi":"10.56434/j.arch.esp.urol.20247707.116","DOIUrl":"10.56434/j.arch.esp.urol.20247707.116","url":null,"abstract":"","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"77 7","pages":"837-838"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lingyan Ding, Siyang Xu, Xinfeng Chen, Cheng Shen, Hua Zhu, Bing Zheng, Wei Zhang, Chunmei Shi
{"title":"Analysis of Risk Factors for Postoperative Recurrence in Elderly Patients with Kidney Stones: A Case-Control Study.","authors":"Lingyan Ding, Siyang Xu, Xinfeng Chen, Cheng Shen, Hua Zhu, Bing Zheng, Wei Zhang, Chunmei Shi","doi":"10.56434/j.arch.esp.urol.20247707.108","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20247707.108","url":null,"abstract":"<p><strong>Objective: </strong>Renal calculi are solid crystals that form in the kidneys and cause severe pain and discomfort. This study aims to investigate risk factors for postoperative recurrence of renal calculi in elderly patients and provide background knowledge on the prevalence and management of renal calculi in this demographic.</p><p><strong>Methods: </strong>The clinical data of 123 elderly patients with renal calculi were included from 1 June 2021 to 1 June 2023 for their 6-month follow-up study. The patients were divided into recurrence group and non-recurrence group according to whether they had recurrence after surgery. The general sociological characteristics and disease-related characteristics of the two groups were counted. Logistic regression equation was used to calculate differences, and the influencing factors of postoperative recurrence in elderly patients with kidney stones were obtained. A receiver operating characteristic (ROC) curve was drawn to analyse the value of the factors in predicting postoperative recurrence in patients with kidney stones.</p><p><strong>Results: </strong>A total of 123 elderly patients with renal calculi were enrolled. The patients were divided according to the presence or absence of stone recurrence into the recurrence group (25 cases, 20.33%) and the non-recurrence group (98 cases, 79.67%). Postoperative water intake, excessive intake of animal protein, exercise and postoperative complications significantly differed between the recurrence group and the non-recurrence group (<i>p</i> < 0.001). Logistic regression analysis showed that the above-mentioned indicators were the influencing factors of postoperative recurrence. The area under the curve (AUC) values of postoperative water intake (AUC = 0.767), animal protein intake (AUC = 0.752), exercise (AUC = 0.707) and postoperative complications (AUC = 0.727) were statistically significant, and they were identified as the most important factors with high sensitivity and specificity and were of high value in predicting postoperative recurrence of renal calculi.</p><p><strong>Conclusions: </strong>Elderly patients with kidney stones are prone to recurrence after surgery. Influencing factors should be given attention, and corresponding measures should be formulated for intervention as soon as possible.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"77 7","pages":"772-778"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mihnea Bogdan Borz, Vlad Horia Schitcu, Bogdan Fetica, Oliviu Cristian Borz, Răzvan Couți, Ion Cojocaru, Ioan Coman
{"title":"Impact of Immunohistochemical Biomarkers on Predicting the Risk of Biochemical Recurrence for Patients that Underwent Radical Prostatectomy: A Literature Review.","authors":"Mihnea Bogdan Borz, Vlad Horia Schitcu, Bogdan Fetica, Oliviu Cristian Borz, Răzvan Couți, Ion Cojocaru, Ioan Coman","doi":"10.56434/j.arch.esp.urol.20247707.100","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20247707.100","url":null,"abstract":"<p><strong>Background: </strong>Prostate cancer (PCa) remains a significant global health issue, exhibiting a spectrum of clinical behaviours from indolent to aggressive. Biomarkers are crucial for risk assessment, treatment selection and prognosis prediction. Despite their importance, accurately evaluating PCa aggressiveness and guiding personalised treatment strategies present challenges. This review aims to evaluate biomarkers for assessing recurrence risk following radical prostatectomy, with a focus on personalised follow-up and timely intervention for high-risk patients. This review assesses the clinical significance of immunohistochemical biomarkers, including LIM domain kinase 1 (LIMK1), Antigen Kiel 67 (Ki67), <i>PTEN</i> and <i>ERG</i>, in PCa management. A comprehensive literature review examined the correlation between these biomarkers and biochemical recurrence (BCR) in patients undergoing radical prostatectomy. Our search included articles published between 2019 and 2024, yielding 87 articles, with 7 focused on the correlation between LIMK1 and BCR, 46 on Ki67 and 34 on <i>PTEN</i>/<i>ERG</i> biomarkers. After applying the exclusion criteria, 36 articles were included for review. LIMK1, a serine/threonine kinase, is highly expressed in cancers like PCa. It influences cell survival and motility through actin cytoskeleton reorganisation, correlating with poor prognosis, aggressive tumour behaviour and BCR. Similarly, Ki67, a marker of cell proliferation, predicts high-risk PCa and worse prognosis, particularly in castration-resistant cases, although its association with recurrence risk remains debated. <i>PTEN</i> loss and <i>ERG</i> fusion are prevalent genetic alterations in PCa, with <i>PTEN</i> loss linked to poor prognosis and <i>ERG</i> fusion associated with increased disease progression and BCR post-prostatectomy. Integrating these biomarkers into clinical practice can enhance risk stratification and inform personalised treatment strategies for patients with PCa. Despite promising findings, further validation studies and standardisation of detection methods are needed to ensure the clinical utility of these biomarkers. Continued research is essential to validate and optimise the clinical utility of these biomarkers, paving the way for more effective PCa management strategies and improved patient outcomes and quality of life.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"77 7","pages":"718-725"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Combined Treatment of Tunnelled Composite Anterior-Lateral Inguinal Skin Flap, Buccal Mucosal Graft and Hyperbaric Oxygen Therapy for Catastrophically Lost Penis after Circumcision.","authors":"Seyithan Özaydın","doi":"10.56434/j.arch.esp.urol.20247707.115","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20247707.115","url":null,"abstract":"<p><strong>Background: </strong>Catastrophic loss of the penis following post-circumcision necrosis is a rare and devastating complication. Treatment options are limited, and the process is highly challenging. This study aims to report the successful application of our combined treatment approach for a 6-year-old patient who experienced total penile loss due to progressive necrosis 1 year after circumcision.</p><p><strong>Methods & results: </strong>Following penile degloving, proximal penile mobilisation and separation and reshaping of the corpora were performed. The penile shaft was covered with a tunnelled composite anterior-lateral inguinal skin flap. Glanuloplasty was performed using a left buccal mucosal graft, followed by 10 sessions of hyperbaric oxygen therapy. At 1.5 months postoperatively, urethral dilation was performed once because of minor voiding difficulties. At 10 months postoperatively, the patient had excellent voiding function and no additional complaints. The patient expressed high satisfaction with the outcome and is still under close follow up.</p><p><strong>Conclusions: </strong>A standard treatment for serious complications such as necrosis and total penile loss has not been established yet. Although scrotal skin flap is a straightforward technique, it was not preferred in our case because of fibrosis following scrotal necrosis and potential risk of hair growth. The developed approach could be an effective alternative to other techniques.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"77 7","pages":"826-836"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yi Li, Jizheng Zhang, Xiaohua Sun, Jinli Che, Wanlu Ren
{"title":"Effect of Oral Gabapentin before Plasmakinetic Resection of the Prostate on Anesthesia Effects in Older Adults with Benign Prostatic Hyperplasia: A Retrospective Study.","authors":"Yi Li, Jizheng Zhang, Xiaohua Sun, Jinli Che, Wanlu Ren","doi":"10.56434/j.arch.esp.urol.20247707.107","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20247707.107","url":null,"abstract":"<p><strong>Objective: </strong>Benign prostatic hyperplasia (BPH) is a common chronic disease affecting the health of the urinary system and the quality of life in older adults. Plasmakinetic resection of the prostate (PKRP) is one of the important surgical procedures for treating BPH; However, older adults may experience anesthesia complications and postoperative pain. This retrospective study aimed to assess the effects of preoperative oral gabapentin on anesthesia outcomes in older adults with BPH undergoing PKRP and to provide detailed clinical evidence for improving the impact of surgical treatment.</p><p><strong>Methods: </strong>The medical records of 178 older adults with BPH who underwent PKRP in Tianjin Hospital from March 2021 to March 2023 were retrospectively analyzed. After excluding 18 patients who did not meet the inclusion criteria, 160 patients were finally included in the study. According to preoperative use of gabapentin, patients were divided into the observation group (n = 75, received gabapentin) and the control group (n = 85, did not receive gabapentin). The baseline data, visual analog scale (VAS) scores, postoperative Ramsay Sedation Scale (RSS) scores, and incidence of adverse reactions were collected.</p><p><strong>Results: </strong>There were no significant differences observed between the two groups in terms of age, body mass index, prostate volume, surgery duration, International Prostate Symptom Score (IPSS), American Society of Anesthesiologists (ASA) classification, history of hypertension and diabetes mellitus, VAS scores at postoperative 36 hours and 48 hours, and RSS scores at postoperative 2 hours, 4 hours, 8 hours, 12 hours, 24 hours, 36 hours, and 48 hours (<i>p</i> > 0.05). Compared to the control group, the observation group had significantly lower VAS scores at postoperative 2 hours, 4 hours, 8 hours, 12 hours, and 24 hours (<i>p</i> < 0.001), and the incidence of adverse reactions was significantly lower within 24 hours after surgery (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>Preoperative administration of gabapentin before PKRP could reduce pain severity and the incidence of adverse reactions and improve anesthetic effects in older adults with BPH, which is conducive to postoperative recovery.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"77 7","pages":"766-771"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of a Remote Multimodal Psychoeducational Intervention Nursing Program on Mental Health and Quality of Life of Renal Cell Carcinoma Survivors: A Retrospective Study.","authors":"Mingzhu Dong, Xiaoting Sun, Ying Hu","doi":"10.56434/j.arch.esp.urol.20247707.110","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20247707.110","url":null,"abstract":"<p><strong>Background: </strong>Undergoing surgery for renal cell carcinoma can potentially compromise the mental well-being and overall quality of life of survivors. Long-term psychological education interventions that are delivered remotely through various modalities have shown promise in enhancing the psychological well-being and quality of life of cancer patients. This study investigates the effect of remote multimodal psychoeducational interventions on mental well-being and quality of life of renal cell carcinoma survivors.</p><p><strong>Methods: </strong>A retrospective study was conducted to compare patients receiving remote psychological interventions (exposure group) with those receiving standard care (control group). Following the interventions, various data sets including general demographic information, and assessments from the Hamilton anxiety scale (HAMA), Hamilton depression scale (HAMD), the Brief Fatigue Inventory-Chinese version (BFI-C), the Distress Thermometer (DT), and the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) were gathered and analysed for comparison.</p><p><strong>Results: </strong>This study included 116 renal cell carcinoma survivors, with 52 in the exposure group and 64 in the control group. Baseline characteristics were not significantly different between the two groups (<i>p</i> > 0.05). After the intervention, the exposure group had significantly lower scores than the control group on HAMA (14.63 vs. 16.66, <i>p</i> < 0.001), HAMD (13.63 vs. 16.36, <i>p</i> < 0.001), BFI-C (52.31 vs. 57.65, <i>p</i> < 0.001), and DT (3.94 vs. 4.98, <i>p</i> < 0.001). Additionally, the exposure group had significantly higher total score of EORTC QLQ-C30 (69.22 vs. 65.59, <i>p</i> < 0.001) than the control group.</p><p><strong>Conclusions: </strong>Remote multimodal psychoeducational interventions demonstrate a notable impact in mitigating adverse emotions, exhaustion, and discomfort experienced by survivors of renal cell carcinoma. Such interventions should be actively promoted in clinical practice.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"77 7","pages":"789-795"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}