Archivos Espanoles De Urologia最新文献

{"title":"An Enhanced Nursing Programme Based on mp-MRI Assessment for Urinary Continence Recovery After Radical Prostatectomy.","authors":"Chunmei Shi, Lingyan Ding, Hua Zhu, Tianle Wang","doi":"10.56434/j.arch.esp.urol.20267906.112","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20267906.112","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the significance of integrating multiparametric magnetic resonance imaging (mp-MRI) assessment with proactive nursing care for patients undergoing radical prostatectomy for prostate cancer.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted, collecting clinical data from 130 patients who underwent radical prostatectomy for prostate cancer in the Department of Urology of the Affiliated Hospital 2 of Nantong University from June 2023 to October 2025. Patients were divided into a study group (n = 65) and a control group (n = 65) based on perioperative nursing care protocols. The control group underwent routine perioperative nursing care in the urology department, whereas the study group received mp-MRI assessment combined with proactive nursing guidance and routine care. The urinary continence recovery rate, urodynamic parameters, nursing compliance and complication rate at different postoperative time points were compared between the two groups.</p><p><strong>Results: </strong>At 6 months postoperative follow-up, the total urinary continence rate (complete + social continence) and the absence of severe incontinence in the study group were significantly higher than those in the control group (<i>p</i> < 0.05), with statistically significant differences between the groups (<i>p</i> < 0.05). Repeated-measures analysis of variance (ANOVA) confirmed significant group effects for all urodynamic parameters, with comparable recovery trajectories between the groups, except for residual urine volume.</p><p><strong>Conclusions: </strong>In this retrospective cohort study, an enhanced nursing programme based on mp-MRI assessment was associated with improved urinary continence recovery and urodynamic parameters in patients undergoing radical prostatectomy. However, these findings require confirmation in prospective randomised controlled trials.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"79 6","pages":"958-968"},"PeriodicalIF":1.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148800259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic Review and Meta-Analysis of Urine-Based Molecular Testing for Urogenital Tuberculosis.","authors":"Lin Fang, Xiaohong Chen, Jiangying Chen, Xiaoqin Liao, Jiandong Lin","doi":"10.56434/j.arch.esp.urol.20267906.114","DOIUrl":"10.56434/j.arch.esp.urol.20267906.114","url":null,"abstract":"<p><strong>Background: </strong>Early confirmation of urogenital tuberculosis (UGTB) remains challenging in routine practice because conventional culture is slow and has variable sensitivity. Urine-based molecular testing has emerged as a rapid alternative, but its performance estimates vary across studies. This systematic review evaluated the diagnostic value of urine-based molecular testing, including Xpert <i>Mycobacterium tuberculosis</i>/rifampicin, multiplex polymerase chain reaction and loop-mediated isothermal amplification, for UGTB.</p><p><strong>Methods: </strong>Risk of bias was assessed using Quality Assessment of Diagnostic Accuracy Studies-2. Pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio (DOR) were generated with a bivariate random-effects model. The summary receiver operating characteristic (SROC) curve and Fagan nomogram were used for visualization.</p><p><strong>Results: </strong>A total of 14 diagnostic accuracy studies, comprising 1697 patients with high clinical suspicion of UGTB, were analysed. Pooled sensitivity was 0.748 (95% confidence interval [CI]: 0.566-0.871), pooled specificity was 0.962 (95% CI: 0.932-0.979), pooled DOR was 121.77 (95% CI: 37.86-391.68), and the area under the SROC curve was 0.93. Studies using bacterial culture as the reference standard yielded a pooled specificity of 1.000, whereas those using a composite reference standard yielded a pooled specificity of 0.934. With a 20% pre-test probability, a positive test increased the post-test probability to 83%, while a negative test lowered it to 6%.</p><p><strong>Conclusions: </strong>Urine-based molecular testing shows high diagnostic accuracy and clinical utility for UGTB. It may serve as an adjunctive test for early rapid confirmation, especially when interpreted alongside clinical, imaging and culture findings. The PROSPERO Registration: The study was registered on https://www.crd.york.ac.uk/prospero/ (registration number: CRD420261373256; registration link: https://www.crd.york.ac.uk/PROSPERO/view/CRD420261373256).</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"79 6","pages":"980-991"},"PeriodicalIF":1.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148800007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiologic and Lipid Metabolism Imaging Features Associated with FABP2 Expression in Clear Cell Renal Cell Carcinoma: An Interpretable Supervised Machine Learning Radiogenomic Study.","authors":"Federico Greco, Marco Cataldo, Andrea Panunzio, Alessandro Tafuri, Bruno Beomonte Zobel, Carlo Augusto Mallio","doi":"10.56434/j.arch.esp.urol.20267905.92","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20267905.92","url":null,"abstract":"<p><strong>Background: </strong>This study investigated the association between computed tomography (CT) features and fatty acid-binding protein 2 (FABP2) gene expression in clear cell renal cell carcinoma (ccRCC), focusing on morphologic and metabolic parameters.</p><p><strong>Methods: </strong>A retrospective analysis was performed on 246 ccRCC patients from The Cancer Genome Atlas (TCGA) and The Cancer Imaging Archive (TCIA). Patients were classified as FABP2-positive (n = 57, 23.17%) or FABP2-negative (n = 189, 76.83%). Clinical, pathological, and imaging features were compared. Quantitative CT assessed mean tumor attenuation and abdominal adipose compartments. Two logistic regression models were built: one based on radiologic features and one on metabolic imaging parameters.</p><p><strong>Results: </strong>FABP2-positive tumors were significantly smaller, more frequently low-grade and diagnosed at an earlier stage. FABP2 expression was more common in male patients. On imaging, FABP2-negative tumors more often exhibited collateral vascular supply. Quantitative CT revealed lower mean attenuation in FABP2-positive tumors, suggesting higher intracellular lipid content. No significant differences were found in hepatic attenuation or abdominal adipose compartments. The radiologic model achieved an area under the curve (AUC) of 0.58, with cystic composition as the strongest predictor of FABP2 positivity. The lipid metabolism-based model showed slightly better performance (AUC 0.61), with mean tumor attenuation as the most influential variable.</p><p><strong>Conclusions: </strong>FABP2-positive ccRCC appears to represent a less aggressive, lipid-rich phenotype. CT attenuation features were weakly associated with FABP2 expression and may offer preliminary, noninvasive insights to support integrated radiogenomic approaches in ccRCC.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"79 5","pages":"791-799"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148431322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-National Differences in Online Search Behavior for Urological Symptoms and Conditions: An Infodemiological Analysis.","authors":"Salim Zengin","doi":"10.56434/j.arch.esp.urol.20267905.96","DOIUrl":"10.56434/j.arch.esp.urol.20267905.96","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to comparatively examine digital search behaviors related to urological symptoms and conditions in Türkiye, the United States, Germany, the United Kingdom, India, and Japan using Google Trends data.</p><p><strong>Materials and methods: </strong>This cross-sectional, observational digital epidemiology study analyzed weekly web search data from the past five years obtained via the Google Trends platform. Ten urological conditions were evaluated: kidney stones, benign prostatic hyperplasia, dysuria, urinary incontinence, erectile dysfunction, premature ejaculation, varicocele, testicular pain, infertility, and penile curvature. Mean Google Trends scores were used for cross-country comparisons, while country-specific digital search profiles were normalized to reflect relative distributions. Searches related to kidney stones were additionally analyzed for seasonal variation. K-means clustering analysis was applied to identify similarities in digital search profiles across countries.</p><p><strong>Results: </strong>Kidney stones were identified as the urological condition with the highest digital search interest in all countries, with increased search activity observed during the summer months. Benign prostatic hyperplasia and dysuria were among the most frequently searched conditions across all countries. Searches related to reproductive and sexual health showed considerable variation between countries. Clustering analysis revealed that the United States, Germany, and the United Kingdom shared similar digital search profiles, whereas India and Japan formed a distinct cluster. Türkiye demonstrated a profile broadly similar to Western countries but with partial divergence.</p><p><strong>Conclusions: </strong>Digital search behaviors related to urological symptoms and conditions exhibit heterogeneous patterns across countries. Google Trends data may serve as a complementary tool for assessing population-level urological health awareness.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"79 5","pages":"823-830"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148431348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction Note: Predictive Value of SAA, AOPP and eNOS for Poor Prognosis of Cystitis and Construction of a Nomogram Model.","authors":"Xiaodi Feng, Dan Sun, Lingfu Xu, Changming Zhu, Wentao Gai, Qian Liu","doi":"10.56434/j.arch.esp.urol.20267905.83","DOIUrl":"10.56434/j.arch.esp.urol.20267905.83","url":null,"abstract":"<p><p>The article has been voluntarily retracted by the authors. After publication, the authors identified discrepancies in the original data and the statistical methods used in the manuscript. To ensure the accuracy and integrity of the scientific record and to uphold the highest standards of publication ethics, all authors have agreed to the retraction of this article. The Editor-in-Chief has reviewed the case and approved the retraction.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"79 5","pages":"709"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148430144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased Risk of Postoperative Hydroureteronephrosis in Patients With Comorbid Cystitis Glandularis, Pelvic Lipomatosis and Single-System Ectopic Ureter: Report of Three Cases.","authors":"Xu Zhang, Derrick Tsang, Junhong Zhai, Qiang Huang, Giorgio Mazzon, Chaojun Wang","doi":"10.56434/j.arch.esp.urol.20267905.102","DOIUrl":"10.56434/j.arch.esp.urol.20267905.102","url":null,"abstract":"<p><strong>Background: </strong>Cystitis glandularis (CG) frequently coexists with pelvic lipomatosis (PL). However, the simultaneous presence of a single-system ectopic ureter (SSEU) has not been previously documented. This anatomical triad results in unusual bladder anatomy and obscured ureteric orifices, potentially increasing the risk of postoperative ureteric obstruction following transurethral resection procedures.</p><p><strong>Methods: </strong>Three patients with confirmed comorbid CG and PL (CG/PL) underwent transurethral resection of cystitis glandularis (TUR-CG) for persistent lower urinary tract symptoms. An SSEU was identified intraoperatively in all cases. Postoperative imaging and clinical outcomes were reviewed, with particular emphasis on the risk of hydroureteronephrosis. Informed consent was obtained from all patients.</p><p><strong>Results: </strong>All patients developed new-onset hydroureteronephrosis within months of TUR-CG despite normal preoperative uppertract imaging. Two required ureteric reimplantation owing to recurrent infection or stent-related stricture. The coexistence of CG, PL, and SSEU resulted in concealed or non-orthotopic ureteric orifices. This increased the likelihood of inadvertent orifice involvement during TUR-CG and complicated subsequent reconstructive surgery.</p><p><strong>Conclusions: </strong>CG/PL, when complicated by unrecognised SSEU, represents a high-risk anatomical configuration in which TURCG may precipitate premature ureteric obstruction. Thorough preoperative imaging, surgical awareness of aberrant ureteric anatomy, careful consideration of surgical indications, and patient counselling are essential for minimising postoperative hydroureteronephrosis and anticipating technical challenges during subsequent ureteric reconstruction.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"79 5","pages":"869-875"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148431355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of 3D-Assisted Preoperative Planning on Surgical and Functional Outcomes of Partial Nephrectomy in Adults: A Systematic Review.","authors":"Mercedes Sanchez-Pedreno Jimenez, Daniel Campos-Valverde, Andrea Gabriela Arcadi, Francisco Donis Canet, Carlos Serret de Troya, Miguel Tellez Martinez-Fornes","doi":"10.56434/j.arch.esp.urol.20267905.86","DOIUrl":"10.56434/j.arch.esp.urol.20267905.86","url":null,"abstract":"<p><strong>Background: </strong>Three-dimensional (3D) imaging is used for preoperative planning of partial-nephrectomy, enhancing visualisation of tumour anatomy, vascular structures, and their spatial relationships. This systematic review evaluated the impact of 3D-assisted planning on surgical, perioperative, and functional outcomes in adults undergoing partial-nephrectomy.</p><p><strong>Methods: </strong>A systematic review was conducted according to PRISMA 2020 guidelines. Eligible studies included adults with clinically localised T1-T2 renal tumours undergoing open, laparoscopic, or robotic partial-nephrectomy, in whom preoperative 3D reconstructions from CT or MRI were compared with conventional two-dimensional planning. Outcomes assessed were positive surgical margins, warm-ischaemia time, postoperative complications, renal function, operative time, estimated blood loss, and hospital stay. Searches of MEDLINE, EMBASE, Cochrane CENTRAL and Web of Science (2015-2025) identified 495 records; after screening and assessment, 9 studies were included.</p><p><strong>Results: </strong>Nine studies reported surgical and functional outcomes of partial-nephrectomy using 3D technology. Positive surgical margin rates were 0-9%, with only one study demonstrating a significant difference favouring the 3D cohort (0% vs 28%). Renal function outcomes were generally comparable, although one study reported superior eGFR preservation in the 3D cohort (80% vs 70% of baseline; <i>p</i> = 0.02). Warm-ischaemia time ranged from 13.5 to 26 minutes, with a significant reduction reported only by one study (24 vs 28 min; <i>p</i> < 0.01). Operative time showed variations across studies (ranging from 105-212 minutes), with two studies showing significant reductions (e.g., 130 vs 160 min; <i>p</i> < 0.05). Estimated blood loss ranged from 50 to 830 mL, and two studies demonstrated significant reductions with 3D imaging (e.g., 591 vs 141 mL; <i>p</i> = 0.019).</p><p><strong>Conclusions: </strong>Available evidence suggests that 3D-assisted preoperative planning may be associated with improvements in selected perioperative outcomes, namely operative time, blood loss, and warm-ischaemia time, while maintaining low positive-margin rates and without increasing postoperative complications or impairing renal function. However, findings are inconsistent and based predominantly on non-randomised studies with small-sample sizes and methodological heterogeneity. Larger prospective studies with standardised outcome reporting are required to possibly define with more accuracy the clinical benefits of 3D planning in partial-nephrectomy. The PROSPERO Registration: CRD420251160851. https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=1160851.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"79 5","pages":"729-740"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148431377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Perioperative Continuous Nursing on Urinary Function Recovery, Lower Urinary Tract Symptom Improvement, and Postoperative Complications After Transurethral Resection of the Prostate.","authors":"Lihua Pan, Junxia Liu, Guangming Ru","doi":"10.56434/j.arch.esp.urol.20267905.99","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20267905.99","url":null,"abstract":"<p><strong>Background: </strong>To investigate the effects of perioperative continuity nursing care on urinary function recovery, improvement in lower urinary tract symptoms, and postoperative complications in patients after transurethral resection of the prostate (TURP).</p><p><strong>Methods: </strong>We analysed the medical records of 193 patients with benign prostatic hyperplasia who underwent TURP at Jieshou People's Hospital between January 2023 and June 2024. Based on the perioperative care regimens actually administered to the patients, they were divided into a control group (n = 95) and a study group (n = 98). Data were collected and compared regarding patients' recovery of urinary function, improvement in lower urinary tract symptoms, inflammatory markers, and postoperative complications.</p><p><strong>Results: </strong>The time to return of spontaneous voiding (TRSV) was significantly shorter in the study group than in the control group; post-void residual volume (PVR) at three months postoperatively was significantly lower in the study group than that in the control group; maximum flow rate (Qmax) was significantly higher in the study group than that in the control group; and the use of 24-hour urine pads at three months postoperatively was significantly less in the study group than that in the control group. At three months post-operatively, the International Prostate Symptom Score (IPSS) in the study group was significantly lower than that in the control group. Five days post-operatively, C-reactive protein (CRP) levels in the study group were significantly lower than those in the control group. The overall incidence of post-operative complications in the study group was 4.49%, which was significantly lower than the incidence (13.48%) observed in the control group.</p><p><strong>Conclusions: </strong>Perioperative continuity nursing care is associated with improved postoperative urinary function, alleviated lower urinary tract symptoms, reduced postoperative inflammatory response and a lower risk of complications in patients undergoing TURP.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"79 5","pages":"847-854"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148431369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integral Perineal Sacrocolpopexy: Expanding Surgical Options for Complex Pelvic Organ Prolapse.","authors":"Rui Pedrosa, Lexie Carmona, Javier Casado, Manuel Saavedra, Clara Velasco, Lira Pelari, Ana Sanchez, Carlos Marquez, Claudia Fernandes, Lucia Polanco-Pujol, Luis San-José, Luis López-Fando","doi":"10.56434/j.arch.esp.urol.20267905.91","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20267905.91","url":null,"abstract":"<p><strong>Background: </strong>Sacrocolpopexy is the gold standard for multicompartimental pelvic organ prolapse (POP). Patients with associated perineal descent presents higher recurrence rates. To address this, we developed the Integral Perineal Sacrocolpopexy (IPSC), a modification designed to increase anterior reinforcement through extended anterior dissection and mesh fixation to the levator ani muscles.</p><p><strong>Methods: </strong>In addition to describing the Integral Perineal Sacrocolpopexy technique, we prospectively analyzed a case series of 15 patients with POP and magnetic resonance imaging (MRI)-confirmed perineal descent, treated between October 2018 and January 2024.</p><p><strong>Results: </strong>The cohort had a median age of 71 years and seven patients had a prior hysterectomy with concomitant prolapse repair. Mean operative time was 145 minutes and median hospital stay was 2 days. No postoperative complications or hospital readmissions occurred. At a median follow-up of 48 months, anatomical success was achieved in all patients. Regarding urinary function, urgency incontinence improved substantially, whereas stress incontinence persisted in one patients and occurred de novo in four. One patient developed late intravesical mesh erosion, treated endoscopically without recurrence.</p><p><strong>Conclusions: </strong>Integral Perineal Sacrocolpopexy appears to be a safe and feasible technique for highly selected patients with compromised pelvic floor support, offering anatomical and functional correction with a complication profile within the range reported for conventional sacrocolpopexy.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"79 5","pages":"783-790"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148431387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Efficacy of Negative Pressure Suction Combined With Digital Flexible Ureteroscopic Holmium Laser Lithotripsy in the Treatment of Infectious Renal Calculi and Its Effect of Perioperative Inflammatory Indicators.","authors":"Ming Gao, Yuanpeng Chen, Wennian Fang","doi":"10.56434/j.arch.esp.urol.20267905.100","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20267905.100","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the clinical efficacy of negative pressure suction combined with flexible ureteroscopic holmium laser lithotripsy (FUHLL) for treating infectious renal calculi and its effect on perioperative inflammatory indicators.</p><p><strong>Methods: </strong>A total of 150 patients with infectious renal calculi admitted to our Department of Urology from January 2023 to December 2025 were retrospectively selected and divided into an observation group (79 cases) and a control group (71 cases) based on the surgical methods used. After propensity score matching, 126 valid cases were finally included, with 63 cases in each group. The control group received conventional digital FUHLL, while the observation group received additional negative pressure aspiration. Perioperative indicators, stone clearance rate, inflammatory indicators at different time points and postoperative complications were compared between the two groups.</p><p><strong>Results: </strong>The observation group had significantly shorter operation duration, postoperative bed rest time, and hospital stay time than the control group (<i>p</i> < 0.05). The stone clearance rate at 4 weeks postoperatively was 93.65% in the observation group, significantly higher than the 85.71% in control group (<i>p</i> < 0.05). At 6, 24, and 72 hours after surgery, levels of inflammatory indicators in the observation group were significantly lower than those in the control group (<i>p</i> < 0.05). The total postoperative complication rate was 4.76% in the observation group, significantly lower than the 20.63% in the control group (<i>p</i> < 0.05). Maximum stone diameter was identified as an independent risk factor for postoperative complications (OR = 16.923, 95% CI: 1.985-144.325, <i>p</i> = 0.010).</p><p><strong>Conclusions: </strong>Negative pressure suction combined with digital flexible ureteroscopic holmium laser lithotripsy effectively improves stone removal efficiency and shorten operation and recovery time.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"79 5","pages":"855-861"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148431352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}