Current Opinion in Supportive and Palliative Care最新文献_第2页

Non-malignant diseases: health outcomes after musculoskeletal injury. 非恶性疾病：肌肉骨骼损伤后的健康结果。

IF 2 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-09-01 Epub Date: 2025-07-29 DOI: 10.1097/SPC.0000000000000766

Michele Sterling, Rachel A Elphinston, Scott F Farrell, Christopher Papic, Yanfei Xie

{"title":"Non-malignant diseases: health outcomes after musculoskeletal injury.","authors":"Michele Sterling, Rachel A Elphinston, Scott F Farrell, Christopher Papic, Yanfei Xie","doi":"10.1097/SPC.0000000000000766","DOIUrl":"10.1097/SPC.0000000000000766","url":null,"abstract":"Purpose of review: Musculoskeletal pain following a road traffic crash is common and incurs substantial personal and economic costs. Current recommended treatments of reassurance and advice to stay active, exercise and simple analgesics are not very effective. This review describes the current evidence for health outcomes and potential processes involved in the persistence of pain. It also outlines promising current and future treatments aimed at the prevention of chronic pain after musculoskeletal injury.Recent findings: Recent literature highlights a more complex clinical presentation including greater pain-related disability and nociplastic pain features of traumatic musculoskeletal pain compared to non-traumatic pain. Some studies have found evidence for the presence of neuropathic pain in a sub-group of patients. Accurate risk-prediction screening tools exist for neck pain following road traffic injury and clinical trials using these tools show promise where treatment is targeted to identified risk factors.Summary: Traumatic musculoskeletal pain is characterised by a more complex, high-burden clinical presentation, with worse health outcomes compared to non-traumatic musculoskeletal pain. There is emerging evidence that multi-factorial stress-related processes, neuroimmune factors, and neuropathic pain may underlie these differences. Early treatments targeting risk factors for poor recovery, including stress symptoms and pro-nociceptive processes show promise in improving outcomes for injured people.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":"155-161"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144664088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuropathic pain considerations in the aging population. 老年人群中神经性疼痛的考虑。

IF 2 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-09-01 Epub Date: 2025-07-29 DOI: 10.1097/SPC.0000000000000769

Gisèle Pickering, Marie-Eva Pickering, Magdalena Kocot-Kępska

{"title":"Neuropathic pain considerations in the aging population.","authors":"Gisèle Pickering, Marie-Eva Pickering, Magdalena Kocot-Kępska","doi":"10.1097/SPC.0000000000000769","DOIUrl":"10.1097/SPC.0000000000000769","url":null,"abstract":"Purpose of review: Neuropathic pain affects especially older persons and this review aims at discussing neuropathic pain prevalence, evaluation and treatment and how to optimize management. Older persons are prone to develop neuropathic pain essentially because aging is associated with an increased incidence of comorbidities, immune dysfunction, higher prevalence of herpes zoster infections, higher occurrence of diabetes, surgical interventions and of central nervous system pathologies.Recent findings: This review underlines recent publications on neuropathic pain in these different pathologies, presents a consensus focused on pharmacotherapy and an algorithm for neuropathic pain management. Combination of pharmacological and non-pharmacological approaches is suggested as essential for optimal care.Summary: Findings underline the high neuropathic pain rate in older persons, the importance of proactively looking for the presence of pain, the adaptation and careful dosing of the pharmacotherapy in the context of adverse events and quality of life. Initiatives on neuropathic pain prevention are budding with surgical care and vaccination but need to be largely expanded to avoid the development of neuropathic pain.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":"150-154"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immersive nature-based virtual reality for chronic pain: from analgesia to accessibility. 沉浸式基于自然的慢性疼痛虚拟现实：从镇痛到可及性。

IF 2 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-09-01 Epub Date: 2025-07-29 DOI: 10.1097/SPC.0000000000000768

Sam Hughes

{"title":"Immersive nature-based virtual reality for chronic pain: from analgesia to accessibility.","authors":"Sam Hughes","doi":"10.1097/SPC.0000000000000768","DOIUrl":"10.1097/SPC.0000000000000768","url":null,"abstract":"Purpose of review: Time spent in nature has been shown to reduce chronic pain symptoms. However, individuals living with high impact chronic pain often face substantial accessibility barriers to nature. Recent advances in immersive virtual reality (VR) provide opportunities to deliver restorative nature-based experiences directly to patients. This review provides key insight to recent advances into nature-based analgesic mechanisms alongside the role of VR in improving access to the therapeutic benefits of nature.Recent findings: Emerging evidence highlights that nature-based VR interventions can engage top-down cognitive, affective and autonomic mechanisms. Experimental studies demonstrate that nature VR can reduce sensitisation within central nociceptive pathways and is associated with activity within key pain-related brain regions. Qualitative research has also highlighted the therapeutic importance of nature experiences and identifies significant physical barriers that hinder access for individuals with chronic pain.Summary: Immersive VR nature interventions present a promising strategy for the self-management of chronic pain. Integrating VR-based nature therapy into existing pain management strategies would help to expand treatment options, especially for patients restricted by physical, geographic, or socioeconomic barriers. Further research should optimise VR protocols, further explore analgesic mechanisms and investigate their efficacy in chronic pain populations.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":"145-149"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144664087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing FACT and EORTC QLQ modules for the assessment of quality of life in patients with hepatobiliary cancers. 比较肝癌治疗功能评估与欧洲癌症研究与治疗组织生活质量问卷模块对肝胆癌患者生活质量的评估。

IF 2 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-09-01 Epub Date: 2025-07-29 DOI: 10.1097/SPC.0000000000000764

Erika Z Chung, Dominic Sferrazza, Shing Fung Lee, Andrew Bottomley, David Cella, Laura A Dawson, Ali Hosni, Adrian W Chan, Edward Chow, Henry C Y Wong

{"title":"Comparing FACT and EORTC QLQ modules for the assessment of quality of life in patients with hepatobiliary cancers.","authors":"Erika Z Chung, Dominic Sferrazza, Shing Fung Lee, Andrew Bottomley, David Cella, Laura A Dawson, Ali Hosni, Adrian W Chan, Edward Chow, Henry C Y Wong","doi":"10.1097/SPC.0000000000000764","DOIUrl":"10.1097/SPC.0000000000000764","url":null,"abstract":"Purpose of the review: Four commonly used quality of life (QoL) questionnaires for patients with hepatobiliary cancers are the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Liver Module (QLQ-LMC21), the Quality of Life Questionnaire Hepatocellular Carcinoma-Specific Module (QLQ-HCC18), the Quality of Life Questionnaire Biliary Tract Cancer and Gallbladder Cancer Module (QLQ-BIL21), and the Functional Assessment of Cancer Therapy-Hepatobiliary (FACT-Hep). The objective of this systematic review is to compare the characteristics and psychometric properties of these four QoL instruments.Recent findings: From 276 studies, 14 were included: QLQ-LMC21 (3), QLQ-HCC18 (6), QLQ-BIL21 (2), and FACT-Hep (3). All were rigorously developed using a multiphase, standardised approach and shown to be psychometrically valid. In the development/validation of the QLQ-LMC21 and QLQ-BIL21, a majority of patients were recruited from European countries, but race was not specified. In contrast, the QLQ-HCC18, despite including a greater proportion of East Asian participants, lacked representation from other regions and races. Furthermore, challenges in assessing jaundice in Asian patients were identified during the validation phase. The FACT-Hep was developed in the United States and only validated in the United States (90% Caucasian) and China. Notably, QLQ-BIL21 was limited by its small sample size ( n = 52) during the Phase III of its development.Summary: The EORTC QLQ-LMC21, QLQ-HCC18, QLQ-BIL21, and FACT-Hep have proven to be reliable, valid, and responsive. However, additional cross-cultural validation studies may enhance global applicability.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":"203-213"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144664086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Promising preclinical approaches to combating cancer-associated cachexia/tissue wasting. 对抗癌症相关恶病质/组织损耗的有希望的临床前方法

IF 2 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-09-01 Epub Date: 2025-07-29 DOI: 10.1097/SPC.0000000000000763

Savannah A Epstein, Aneesha Dasgupta, Jason D Doles

引用次数: 0

Cancer cachexia: exploring parallels with other paraneoplastic syndromes. 癌症恶病质：探索与其他副肿瘤综合征的相似之处。

IF 2 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-09-01 Epub Date: 2025-07-29 DOI: 10.1097/SPC.0000000000000762

Michael S Yule, Amy Ireland, Barry J A Laird, Richard J E Skipworth

{"title":"Cancer cachexia: exploring parallels with other paraneoplastic syndromes.","authors":"Michael S Yule, Amy Ireland, Barry J A Laird, Richard J E Skipworth","doi":"10.1097/SPC.0000000000000762","DOIUrl":"10.1097/SPC.0000000000000762","url":null,"abstract":"Purpose of review: Cancer cachexia (CC) is a paraneoplastic syndrome (PNS) that is characterised by anorexia, weight loss, fatigue and reduced function. This review explores the molecular drivers of CC and other PNS, identifying shared pathways and highlighting unexplored gaps in research.Recent findings: Recent studies have provided further evidence of pro-inflammatory cytokines, such as interleukin-6 and tumour necrosis factor-α, as central players in both CC and PNS, emphasising their role in systemic effects like muscle wasting, lipolysis and pyrexia. Despite these overlaps between syndromes, cytokine profiles vary across different cancer types with one study highlighting that the interplay between multiple cytokines likely plays a more significant role in cancer phenotypes than individual cytokines. Mediators, such as parathyroid hormone related peptide and vascular endothelial growth factor, which are typically associated with malignant hyperkalaemia and hypertrophic osteoarthropathy respectively, have also been linked to cachexia, suggesting a shared role.Summary: This review highlights the overlap between CC and other PNS. Exploring these shared mechanisms can bridge research gaps and improve CC treatment strategies. Similar insights may be gained by examining other conditions which overlap with CC such as eating disorders, bariatric surgery and sepsis.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":"180-187"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinically assisted hydration in advanced cancer. 临床辅助水合治疗晚期癌症。

IF 2 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-09-01 Epub Date: 2025-07-29 DOI: 10.1097/SPC.0000000000000760

Andrew Davies

引用次数: 0

Integrated nutritional care in cancer; about time? 癌症综合营养护理；约时间吗?

IF 2 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-09-01 Epub Date: 2025-07-29 DOI: 10.1097/SPC.0000000000000765

Kristin Solheim Hustad, Stein Kaasa, Barry J A Laird

{"title":"Integrated nutritional care in cancer; about time?","authors":"Kristin Solheim Hustad, Stein Kaasa, Barry J A Laird","doi":"10.1097/SPC.0000000000000765","DOIUrl":"10.1097/SPC.0000000000000765","url":null,"abstract":"Purpose: Nutritional care is consistently overlooked in oncology practice. It is a critical factor everyone acknowledges, but few actively address, leaving patients neglected. This article explores the challenges of ensuring optimal nutritional care in oncology.Recent findings: Significant disparities have been identified among key cancer nutrition guidelines issued by the European Society for Clinical Nutrition and Metabolism (ESPEN), the European Society for Medical Oncology (ESMO) and the American Society for Clinical Oncology (ASCO). While some emphasise comprehensive nutritional assessments, others focus on pharmacological interventions. Although aligning guideline recommendations with the Global Leadership Initiative on Malnutrition (GLIM) criteria can be complex, there are shared principles that support effective identification and management of malnutrition and cachexia in clinical settings. The key barriers that oncology health professionals face are also highlighted as these are likely to impeded good nutritional care.Summary: There is a need for a standardised, pragmatic approach in assessment and management of nutrition in patients with cancer. This will facilitate the integration of nutrition into cancer care and help overcome barriers. Emerging digital solutions may serve as a conduit to improve nutritional cancer care and enhance communication between patients and healthcare providers and streamline evidence-based nutritional care in oncology.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":"198-202"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cough and dyspnea management in pulmonary fibrosis. 肺纤维化患者咳嗽和呼吸困难的处理。

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-06-01 Epub Date: 2025-03-25 DOI: 10.1097/SPC.0000000000000753

Allard van Veelen, Marlies S Wijsenbeek, Thomas Koudstaal

{"title":"Cough and dyspnea management in pulmonary fibrosis.","authors":"Allard van Veelen, Marlies S Wijsenbeek, Thomas Koudstaal","doi":"10.1097/SPC.0000000000000753","DOIUrl":"10.1097/SPC.0000000000000753","url":null,"abstract":"Purpose of the review: Pulmonary fibrosis (PF) is characterized by relentless scarring of the lungs, declining lung function, and increasing symptom burden. In PF, dyspnea and cough are the most common symptoms, severely impacting quality of life. This review highlights recent advances in understanding their mechanisms and explores evolving strategies for management of these symptoms.Recent findings: Advances in non-pharmacologic approaches, including hand-held fans, dyspnea services and pulmonary rehabilitation are playing a vital role in dyspnea management. Opioids, while effective in reducing exertional dyspnea in controlled settings, show limited benefit for daily life breathlessness and are associated with significant adverse events, highlighting the need for cautious, individualized use. For refractory cough, promising studies are investigating the role of opioids and neuromodulatory therapies. Non-pharmacologic approaches, including speech therapy, and behavioral interventions, provide complementary approaches. A multidisciplinary approach and individualized care plans to address the multifactorial nature of dyspnea and cough are key.Summary: Effective management of dyspnea and cough can importantly improve patients' quality of life. Further research is required to refine treatment protocols, optimize palliative care interventions, and identify and test novel therapeutics. Translation of these findings into clinical practice requires a focus on evidence-based, patient-centered care.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":"103-110"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The invisibility of chronic breathlessness. Why don't we talk about the symptom? 慢性呼吸困难的隐形。我们为什么不谈谈症状呢？

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-06-01 Epub Date: 2025-04-24 DOI: 10.1097/SPC.0000000000000759

Slavica Kochovska, Vanessa N Brunelli, David C Currow

{"title":"The invisibility of chronic breathlessness. Why don't we talk about the symptom?","authors":"Slavica Kochovska, Vanessa N Brunelli, David C Currow","doi":"10.1097/SPC.0000000000000759","DOIUrl":"https://doi.org/10.1097/SPC.0000000000000759","url":null,"abstract":"Purpose of review: Chronic breathlessness is distressing and debilitating, yet often under-recognised. This review summarises recent insights into the visibility of breathlessness and delineates potential contributing factors to its invisibility.Recent findings: Chronic breathlessness' invisibility is multi-faceted and often leads to avoidance behaviour by patients. The symptom's presence, severity and impacts can be hidden from patients, caregivers, clinicians and the public due to its insidiousness, supposed subjectivity, stigma and the ability to be modulated by reducing exertion. This leads to patients' under-reporting of their breathlessness in clinic and low levels of public unawareness. Other contributing factors can include clinicians' failure to initiate conversations about breathlessness at times because of lack of knowledge about assessment and treatment, or prioritising disease management over symptom management.Summary: There is robust evidence that chronic breathlessness is often missed, unacknowledged or misunderstood by patients, caregivers, clinicians and society. Optimised clinical recognition and response may help to reverse these trends. Longitudinal studies are needed to explore whether such perceptions can be changed. Intervention studies should address every aspect of invisibility - from clinical improvements to minimising stigma and validating the subjective experience of patients.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":"19 2","pages":"77-82"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0