Current Opinion in Supportive and Palliative Care最新文献_第10页

Cancer survivor late-effects, chronic health problems after cancer treatment: what's the evidence from population and registry data and where are the gaps? 癌症幸存者的晚期效应、癌症治疗后的慢性健康问题：来自人口和登记数据的证据是什么，差距在哪里？

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2024-03-01 Epub Date: 2024-12-30 DOI: 10.1097/SPC.0000000000000692

Sara Faithfull, Diana Greenfield

{"title":"Cancer survivor late-effects, chronic health problems after cancer treatment: what's the evidence from population and registry data and where are the gaps?","authors":"Sara Faithfull, Diana Greenfield","doi":"10.1097/SPC.0000000000000692","DOIUrl":"10.1097/SPC.0000000000000692","url":null,"abstract":"Purpose of review: Improvements in cancer treatment have led to more people living with and beyond a cancer diagnosis but survivors may have increased health problems as they age. The purpose of this review is to critically evaluate population data exploring incidence of late effects for cancer survivors.Recent findings: 18 studies were identified between 2013 and 2023 that explored the impact on survivors' physical and emotional health. Patients who had been treated at least 2 years previously for cancer had significant cardiovascular risk factors compared with age-matched controls. Women with breast cancer were more likely to have cardiovascular disease, including hypertension, arrythmias and congestive heart failure. This was associated with anthracyclines and/or trastuzumab as part of systemic anti-cancer therapy. Survivors of colorectal cancer were three times more likely to have acute kidney injury than age-matched controls. Stress and mood disorders were higher in survivors of testicular cancer and prostate cancer.Summary: Population studies are important to identify the 'real world' consequences of cancer and its treatment beyond clinical trials. Knowledge is critical for managing an ageing cancer population. Data to personalise cancer survivorship care, not only helps determine potential health risks, but can improve secondary prevention, emotional health, recovery, and long-term outcomes.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":"55-64"},"PeriodicalIF":1.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139089130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Supportive and palliative care for older adults with cancer; facilitating person-centred, age friendly care. 为患有癌症的老年人提供支持性和姑息治疗；促进以人为本的老年友好型护理。

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2024-03-01 Epub Date: 2024-01-31 DOI: 10.1097/SPC.0000000000000689

Christopher B Steer, Schroder Sattar, Ines Menjak

引用次数: 0

Age-friendly healthcare: integrating the 4Ms to enable age-friendly cancer care. 老年友好型医疗保健：整合 4Ms 以实现老年友好型癌症护理。

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2024-03-01 Epub Date: 2024-01-04 DOI: 10.1097/SPC.0000000000000687

Oliver Hodge, Tshepo Rasekaba, Irene Blackberry, Christopher B Steer

{"title":"Age-friendly healthcare: integrating the 4Ms to enable age-friendly cancer care.","authors":"Oliver Hodge, Tshepo Rasekaba, Irene Blackberry, Christopher B Steer","doi":"10.1097/SPC.0000000000000687","DOIUrl":"10.1097/SPC.0000000000000687","url":null,"abstract":"Purpose of review: There is a growing movement towards person-centred, age-friendly healthcare in the care of older adults, including those with cancer. The Age-Friendly Health Systems (AFHS) initiative uses the 4Ms framework to enable this change. This review documents the utility and implications of 4Ms implementation across different settings, with a particular focus on cancer care.Recent findings: The AFHS initiative 4Ms framework uses a set of core, evidence-based guidelines (focussing on What Matters, Medication, Mentation and Mobility) to improve person-centred care. The successful implementation of the 4Ms has been documented in many different healthcare settings including orthopaedics primary care, and cancer care. Implementation of the 4Ms framework into existing workflows complements the use of geriatric assessment to improve care of older adults with cancer. Models for implementation of the 4Ms within a cancer centre are described. Active engagement and education of healthcare providers is integral to success. Solutions to implementing the What Matters component are addressed.Summary: Cancer centres can successfully implement the 4Ms framework into existing workflows through a complex change management process and development of infrastructure that engages healthcare providers, facilitating cultural change whilst employing quality improvement methodology to gradually adapt the status quo to age-friendly processes.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":"9-15"},"PeriodicalIF":1.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence, description, predictors, and consequences of persistent taxane-induced peripheral neuropathy. 持续性紫杉类药物诱发的周围神经病变的发生率、描述、预测因素和后果。

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2023-12-06 DOI: 10.1097/spc.0000000000000684

Daniel L Hertz

引用次数: 0

Exercise interventions for frail older adults with cancer. 对患有癌症的体弱老年人进行运动干预。

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2023-12-06 DOI: 10.1097/spc.0000000000000685

Schroder Sattar, Kristen R Haase, Kayoung Lee, Kristin L Campbell

引用次数: 0

Mechanisms inherent in acute-to-chronic pain after surgery - risk, diagnostic, predictive, and prognostic factors. 手术后急性到慢性疼痛的内在机制——风险、诊断、预测和预后因素。

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2023-12-01 Epub Date: 2023-09-08 DOI: 10.1097/SPC.0000000000000673

Daniela C Rosenberger, Daniel Segelcke, Esther M Pogatzki-Zahn

{"title":"Mechanisms inherent in acute-to-chronic pain after surgery - risk, diagnostic, predictive, and prognostic factors.","authors":"Daniela C Rosenberger, Daniel Segelcke, Esther M Pogatzki-Zahn","doi":"10.1097/SPC.0000000000000673","DOIUrl":"10.1097/SPC.0000000000000673","url":null,"abstract":"Purpose of review: Pain is an expected consequence of a surgery, but it is far from being well controlled. One major complication of acute pain is its risk of persistency beyond healing. This so-called chronic post-surgical pain (CPSP) is defined as new or increased pain due to surgery that lasts for at least 3 months after surgery. CPSP is frequent, underlies a complex bio-psycho-social process and constitutes an important socioeconomic challenge with significant impact on patients' quality of life. Its importance has been recognized by its inclusion in the eleventh version of the ICD (International Classification of Diseases).Recent findings: Evidence for most pharmacological and non-pharmacological interventions preventing CPSP is inconsistent. Identification of associated patient-related factors, such as psychosocial aspects, comorbidities, surgical factors, pain trajectories, or biomarkers may allow stratification and selection of treatment options based on underlying individual mechanisms. Consequently, the identification of patients at risk and implementation of individually tailored, preventive, multimodal treatment to reduce the risk of transition from acute to chronic pain is facilitated.Summary: This review will give an update on current knowledge on mechanism-based risk, prognostic and predictive factors for CPSP in adults, and preventive and therapeutic approaches, and how to use them for patient stratification in the future.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":"324-337"},"PeriodicalIF":2.1,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10215493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Should opioids be used for breathlessness and in whom? A PRO and CON debate of the evidence. 阿片类药物应该用于治疗呼吸困难吗?用于治疗谁?证据的正反辩论。

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2023-12-01 Epub Date: 2023-10-26 DOI: 10.1097/SPC.0000000000000674

Magnus Ekström, Daisy J A Janssen

{"title":"Should opioids be used for breathlessness and in whom? A PRO and CON debate of the evidence.","authors":"Magnus Ekström, Daisy J A Janssen","doi":"10.1097/SPC.0000000000000674","DOIUrl":"10.1097/SPC.0000000000000674","url":null,"abstract":"Purpose of review The net clinical benefit of opioids for chronic breathlessness has been challenged by recent randomized clinical trials. The purpose was to review and weigh the evidence for and against opioid treatment for chronic breathlessness in people with serious disease. Recent findings Evidence to date on the efficacy and safety of opioids for chronic breathlessness was reviewed. Findings supporting a benefit from opioids in meta-analyses of earlier, mostly smaller trials were not confirmed by recent larger trials. Evidence pertains mostly to people with chronic obstructive pulmonary disease but also to people with pulmonary fibrosis, heart failure, and advanced cancer. Taken together, there is no consistent evidence to generally recommend opioids for severe breathlessness or to identify people who are more likely to benefit. Opioid treatment may be tested in patients with intractable breathlessness and limited other treatment options, such as in end-of-life care. Knowledge gaps were identified and recommendations were made for future research. Summary Key Points Supportive findings of net benefit of opioids for chronic breathlessness in earlier trials have not been confirmed by recent larger randomized clinical trials. There is no evidence that the opioid treatment improves the person’s exercise capacity or quality of life, and it increases the risk of adverse events. Evidence to date does not support that opioids should generally be recommended for treating breathlessness. In people with intractable symptoms and short expected survival, with few or no treatment options, it may still be reasonable to try opioid treatment with the aim to alleviate severe breathlessness. Research is needed to explore the potential benefit of opioids in selected patient groups. Opioids cannot be generally recommended for treating breathlessness based on insufficient evidence for net clinical benefit.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":"263-269"},"PeriodicalIF":2.1,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10291345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radiation therapy options in kidney cancer. 肾癌的放射治疗选择。

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2023-12-01 Epub Date: 2023-10-26 DOI: 10.1097/SPC.0000000000000683

Nicholas G Zaorsky, Alexander V Louie, Shankar Siva

引用次数: 0

Perioperative systemic therapy in renal cell carcinoma. 肾细胞癌的围手术期全身治疗。

IF 2.1 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2023-12-01 Epub Date: 2023-10-06 DOI: 10.1097/SPC.0000000000000675

Ceilidh MacPhail, Lori A Wood, Myuran Thana

引用次数: 0

The role of corticosteroids in the palliation of dyspnea in cancer patients: an evidence-based review. 皮质类固醇在缓解癌症患者呼吸困难中的作用：循证综述。

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2023-12-01 Epub Date: 2023-09-29 DOI: 10.1097/SPC.0000000000000677

David Hui, Sriram Yennurajalingam

{"title":"The role of corticosteroids in the palliation of dyspnea in cancer patients: an evidence-based review.","authors":"David Hui, Sriram Yennurajalingam","doi":"10.1097/SPC.0000000000000677","DOIUrl":"10.1097/SPC.0000000000000677","url":null,"abstract":"Purpose of review: To provide an evidence-based review on the use of corticosteroids for dyspnea in cancer patients.Recent findings: Corticosteroids are commonly used for palliation of dyspnea; however, there is wide variation in how they are prescribed due to the paucity of high-quality evidence. Some clinicians would offer corticosteroids routinely regardless of the causes of dyspnea, while others would only prescribe corticosteroids selectively for specific indications, such as lymphangitic carcinomatosis, upper airway obstruction, superior vena cava obstruction, and cancer treatment-induced pneumonitis. Few mechanistic studies have been conducted to support the use of corticosteroids in cancer patients. Two double-blind, placebo-controlled randomized trials have examined the routine use of high-dose dexamethasone for dyspnea in cancer patients. A pilot study suggested some benefits, but the larger confirmatory trial revealed no improvement compared to the placebo and significantly more adverse events. The selective use of corticosteroids use is only based on observational studies such as case series.Summary: The unfavorable risk:benefit ratio of high-dose dexamethasone suggests that it should not be routinely prescribed for dyspnea in cancer patients. More research is needed to assess the selective use of corticosteroids and identify patients most likely be benefit from corticosteroid use.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":"270-276"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41161096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0