Current Opinion in Supportive and Palliative Care最新文献

Recent advances and future directions in spinal cord stimulation for chronic pain: a multidisciplinary perspective. 脊髓刺激治疗慢性疼痛的最新进展和未来方向：多学科视角。

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-07-21 DOI: 10.1097/SPC.0000000000000767

Nantthasorn Zinboonyahgoon, Choopong Luansritisakul, Bunpot Sithinamsuwan, Mark Plazier, Nilesh Patel

{"title":"Recent advances and future directions in spinal cord stimulation for chronic pain: a multidisciplinary perspective.","authors":"Nantthasorn Zinboonyahgoon, Choopong Luansritisakul, Bunpot Sithinamsuwan, Mark Plazier, Nilesh Patel","doi":"10.1097/SPC.0000000000000767","DOIUrl":"https://doi.org/10.1097/SPC.0000000000000767","url":null,"abstract":"Purpose of review: This review aims to provide a comprehensive, multidisciplinary perspective on recent advancements and future directions in spinal cord stimulation (SCS) for chronic pain management. It emphasizes the evolving science of patient selection, technological innovations, cost-effectiveness considerations, and future direction of SCS in pain medicine.Recent findings: Significant progress has been made in optimizing patient outcomes through refined patient selection, including validated data driven predictive tool which integrated psychological profiling and standard trial stimulation protocol. Technological advancements such as closed-loop stimulation and new waveform have improved efficacy, durability, and patient satisfaction. While SCS is cost-effective in high-income countries, economic evaluations in low- and middle-income settings, such as Thailand, have not yet considered it a cost-effective treatment due to differences in willingness to pay and the cost of conservative treatment. Future direction of SCS may include, restorative SCS for spinal cord injury, new waveforms such as sub-perception stimulation, and multimodal neuromodulation.Summary: SCS has undergone many significant transformations in recent years. The integration of clinical, psychosocial and technological knowledge are and will be the key success factors of this transformation. Multidisciplinary collaboration, ongoing research, and the adoption of advanced technologies promise to further personalize and advance therapy.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrated nutritional care in cancer; about time? 癌症综合营养护理；约时间吗?

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-07-21 DOI: 10.1097/SPC.0000000000000765

Kristin Solheim Hustad, Stein Kaasa, Barry J A Laird

{"title":"Integrated nutritional care in cancer; about time?","authors":"Kristin Solheim Hustad, Stein Kaasa, Barry J A Laird","doi":"10.1097/SPC.0000000000000765","DOIUrl":"https://doi.org/10.1097/SPC.0000000000000765","url":null,"abstract":"Purpose: Nutritional care is consistently overlooked in oncology practice. It is a critical factor everyone acknowledges, but few actively address, leaving patients neglected. This article explores the challenges of ensuring optimal nutritional care in oncology.Recent findings: Significant disparities have been identified among key cancer nutrition guidelines issued by the European Society for Clinical Nutrition and Metabolism (ESPEN), the European Society for Medical Oncology (ESMO) and the American Society for Clinical Oncology (ASCO). While some emphasise comprehensive nutritional assessments, others focus on pharmacological interventions. Although aligning guideline recommendations with the Global Leadership Initiative on Malnutrition (GLIM) criteria can be complex, there are shared principles that support effective identification and management of malnutrition and cachexia in clinical settings. The key barriers that oncology health professionals face are also highlighted as these are likely to impeded good nutritional care.Summary: There is a need for a standardised, pragmatic approach in assessment and management of nutrition in patients with cancer. This will facilitate the integration of nutrition into cancer care and help overcome barriers. Emerging digital solutions may serve as a conduit to improve nutritional cancer care and enhance communication between patients and healthcare providers and streamline evidence-based nutritional care in oncology.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immersive Nature-based Virtual Reality for Chronic Pain: From Analgesia to Accessibility. 沉浸式基于自然的慢性疼痛虚拟现实：从镇痛到可及性。

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-07-18 DOI: 10.1097/SPC.0000000000000768

Sam Hughes

{"title":"Immersive Nature-based Virtual Reality for Chronic Pain: From Analgesia to Accessibility.","authors":"Sam Hughes","doi":"10.1097/SPC.0000000000000768","DOIUrl":"https://doi.org/10.1097/SPC.0000000000000768","url":null,"abstract":"Purpose of review: Time spent in nature has been shown to reduce chronic pain symptoms. However, individuals living with high impact chronic pain often face substantial accessibility barriers to nature. Recent advances in immersive virtual reality (VR) provide opportunities to deliver restorative nature-based experiences directly to patients. This review provides key insight to recent advances into nature-based analgesic mechanisms alongside the role of VR in improving access to the therapeutic benefits of nature.Recent findings: Emerging evidence highlights that nature-based VR interventions can engage top-down cognitive, affective and autonomic mechanisms. Experimental studies demonstrate that nature VR can reduce sensitisation within central nociceptive pathways and is associated with activity within key pain-related brain regions. Qualitative research has also highlighted the therapeutic importance of nature experiences and identifies significant physical barriers that hinder access for individuals with chronic pain.Summary: Immersive VR nature interventions present a promising strategy for the self-management of chronic pain. Integrating VR-based nature therapy into existing pain management strategies would help to expand treatment options, especially for patients restricted by physical, geographic, or socioeconomic barriers. Further research should optimise VR protocols, further explore analgesic mechanisms and investigate their efficacy in chronic pain populations.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144664087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-malignant diseases: health outcomes after musculoskeletal injury. 非恶性疾病：肌肉骨骼损伤后的健康结果。

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-07-18 DOI: 10.1097/SPC.0000000000000766

Michele Sterling, Rachel A Elphinston, Scott F Farrell, Christopher Papic, Yanfei Xie

{"title":"Non-malignant diseases: health outcomes after musculoskeletal injury.","authors":"Michele Sterling, Rachel A Elphinston, Scott F Farrell, Christopher Papic, Yanfei Xie","doi":"10.1097/SPC.0000000000000766","DOIUrl":"https://doi.org/10.1097/SPC.0000000000000766","url":null,"abstract":"Purpose of review: Musculoskeletal pain following a road traffic crash is common and incurs substantial personal and economic costs. Current recommended treatments of reassurance and advice to stay active, exercise and simple analgesics are not very effective. This review describes the current evidence for health outcomes and potential processes involved in the persistence of pain. It also outlines promising current and future treatments aimed at the prevention of chronic pain after musculoskeletal injury.Recent findings: Recent literature highlights a more complex clinical presentation including greater pain-related disability and nociplastic pain features of traumatic musculoskeletal pain compared to non-traumatic pain. Some studies have found evidence for the presence of neuropathic pain in a sub-group of patients. Accurate risk-prediction screening tools exist for neck pain following road traffic injury and clinical trials using these tools show promise where treatment is targeted to identified risk factors.Summary: Traumatic musculoskeletal pain is characterised by a more complex, high-burden clinical presentation, with worse health outcomes compared to non-traumatic musculoskeletal pain. There is emerging evidence that multi-factorial stress-related processes, neuroimmune factors, and neuropathic pain may underlie these differences. Early treatments targeting risk factors for poor recovery, including stress symptoms and pro-nociceptive processes show promise in improving outcomes for injured people.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144664088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing Functional Assessment of Cancer Therapy and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire modules for the assessment of quality of life in patients with hepatobiliary cancers. 比较肝癌治疗功能评估与欧洲癌症研究与治疗组织生活质量问卷模块对肝胆癌患者生活质量的评估。

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-07-18 DOI: 10.1097/SPC.0000000000000764

Erika Z Chung, Dominic Sferrazza, Shing Fung Lee, Andrew Bottomley, David Cella, Laura A Dawson, Ali Hosni, Adrian W Chan, Edward Chow, Henry C Y Wong

{"title":"Comparing Functional Assessment of Cancer Therapy and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire modules for the assessment of quality of life in patients with hepatobiliary cancers.","authors":"Erika Z Chung, Dominic Sferrazza, Shing Fung Lee, Andrew Bottomley, David Cella, Laura A Dawson, Ali Hosni, Adrian W Chan, Edward Chow, Henry C Y Wong","doi":"10.1097/SPC.0000000000000764","DOIUrl":"https://doi.org/10.1097/SPC.0000000000000764","url":null,"abstract":"Purpose of the review: Four commonly used quality of life (QoL) questionnaires for patients with hepatobiliary cancers are the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Liver Module (QLQ-LMC21), the Quality of Life Questionnaire Hepatocellular Carcinoma-Specific Module (QLQ-HCC18), the Quality of Life Questionnaire Biliary Tract Cancer and Gallbladder Cancer Module (QLQ-BIL21), and the Functional Assessment of Cancer Therapy-Hepatobiliary (FACT-Hep). The objective of this systematic review is to compare the characteristics and psychometric properties of these four QoL instruments.Recent findings: From 276 studies, 14 were included: QLQ-LMC21 (3), QLQ-HCC18 (6), QLQ-BIL21 (2), and FACT-Hep (3). All were rigorously developed using a multiphase, standardised approach and shown to be psychometrically valid. In the development/validation of the QLQ-LMC21 and QLQ-BIL21, a majority of patients were recruited from European countries, but race was not specified. In contrast, the QLQ-HCC18, despite including a greater proportion of East Asian participants, lacked representation from other regions and races. Furthermore, challenges in assessing jaundice in Asian patients were identified during the validation phase. The FACT-Hep was developed in the United States and only validated in the United States (90% Caucasian) and China. Notably, QLQ-BIL21 was limited by its small sample size (n = 52) during the Phase III of its development.Summary: The EORTC QLQ-LMC21, QLQ-HCC18, QLQ-BIL21, and FACT-Hep have proven to be reliable, valid, and responsive. However, additional cross-cultural validation studies may enhance global applicability.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144664086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing the impact of early palliative care intervention in patients with lung cancer, cachexia and weight loss. 评估早期姑息治疗干预对肺癌、恶病质和体重减轻患者的影响。

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-07-14 DOI: 10.1097/SPC.0000000000000772

Iain Phillips, Charlie Hall, Mark Stares

引用次数: 0

Neuropathic pain considerations in the aging population. 老年人群中神经性疼痛的考虑。

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-07-14 DOI: 10.1097/SPC.0000000000000769

Gisèle Pickering, Marie-Eva Pickering, Magdalena Kocot-Kępska

{"title":"Neuropathic pain considerations in the aging population.","authors":"Gisèle Pickering, Marie-Eva Pickering, Magdalena Kocot-Kępska","doi":"10.1097/SPC.0000000000000769","DOIUrl":"https://doi.org/10.1097/SPC.0000000000000769","url":null,"abstract":"Purpose of review: Neuropathic pain affects especially older persons and this review aims at discussing neuropathic pain prevalence, evaluation and treatment and how to optimize management. Older persons are prone to develop neuropathic pain essentially because aging is associated with an increased incidence of comorbidities, immune dysfunction, higher prevalence of herpes zoster infections, higher occurrence of diabetes, surgical interventions and of central nervous system pathologies.Recent findings: This review underlines recent publications on neuropathic pain in these different pathologies, presents a consensus focused on pharmacotherapy and an algorithm for neuropathic pain management. Combination of pharmacological and non-pharmacological approaches is suggested as essential for optimal care.Summary: Findings underline the high neuropathic pain rate in older persons, the importance of proactively looking for the presence of pain, the adaptation and careful dosing of the pharmacotherapy in the context of adverse events and quality of life. Initiatives on neuropathic pain prevention are budding with surgical care and vaccination but need to be largely expanded to avoid the development of neuropathic pain.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Promising preclinical approaches to combating cancer-associated cachexia/tissue wasting. 对抗癌症相关恶病质/组织损耗的有希望的临床前方法

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-06-10 DOI: 10.1097/SPC.0000000000000763

Savannah A Epstein, Aneesha Dasgupta, Jason D Doles

引用次数: 0

Cough and dyspnea management in pulmonary fibrosis. 肺纤维化患者咳嗽和呼吸困难的处理。

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-06-01 Epub Date: 2025-03-25 DOI: 10.1097/SPC.0000000000000753

Allard van Veelen, Marlies S Wijsenbeek, Thomas Koudstaal

{"title":"Cough and dyspnea management in pulmonary fibrosis.","authors":"Allard van Veelen, Marlies S Wijsenbeek, Thomas Koudstaal","doi":"10.1097/SPC.0000000000000753","DOIUrl":"10.1097/SPC.0000000000000753","url":null,"abstract":"Purpose of the review: Pulmonary fibrosis (PF) is characterized by relentless scarring of the lungs, declining lung function, and increasing symptom burden. In PF, dyspnea and cough are the most common symptoms, severely impacting quality of life. This review highlights recent advances in understanding their mechanisms and explores evolving strategies for management of these symptoms.Recent findings: Advances in non-pharmacologic approaches, including hand-held fans, dyspnea services and pulmonary rehabilitation are playing a vital role in dyspnea management. Opioids, while effective in reducing exertional dyspnea in controlled settings, show limited benefit for daily life breathlessness and are associated with significant adverse events, highlighting the need for cautious, individualized use. For refractory cough, promising studies are investigating the role of opioids and neuromodulatory therapies. Non-pharmacologic approaches, including speech therapy, and behavioral interventions, provide complementary approaches. A multidisciplinary approach and individualized care plans to address the multifactorial nature of dyspnea and cough are key.Summary: Effective management of dyspnea and cough can importantly improve patients' quality of life. Further research is required to refine treatment protocols, optimize palliative care interventions, and identify and test novel therapeutics. Translation of these findings into clinical practice requires a focus on evidence-based, patient-centered care.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":"103-110"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of the benefits of bone modifying agents in the management of advanced breast, prostate, and lung cancers. 评估骨修饰剂在晚期乳腺癌、前列腺癌和肺癌治疗中的益处。

IF 1.9 4区医学

Current Opinion in Supportive and Palliative Care Pub Date : 2025-06-01 Epub Date: 2025-02-14 DOI: 10.1097/SPC.0000000000000749

Jennifer Leigh, Shing Fung Lee, Ali Fawaz, Jason Jia, Christopher F Theriau, Jessica Rodrigues, Janet Brown, Terry L Ng

{"title":"Assessment of the benefits of bone modifying agents in the management of advanced breast, prostate, and lung cancers.","authors":"Jennifer Leigh, Shing Fung Lee, Ali Fawaz, Jason Jia, Christopher F Theriau, Jessica Rodrigues, Janet Brown, Terry L Ng","doi":"10.1097/SPC.0000000000000749","DOIUrl":"10.1097/SPC.0000000000000749","url":null,"abstract":"Purpose of review: Skeletal metastases occur in approximately 80% of advanced breast, 70% of advanced prostate, and 30% of lung cancers, and place patients at increased risk of skeletal related events (SRE). Bone modifying agents (BMAs) have been shown to prevent or delay SRE development. Our objective was to summarize the role of these agents in the management of these three cancers.Recent findings: Total 52 studies met our inclusion criteria. These highlighted the benefit of BMAs in reducing SREs in metastatic breast and castrate resistant prostate cancer (mCRPC), with less clear impact on reducing SRE in lung cancer, or on improving progression-free and overall survival due to significant heterogeneity in trial design and outcomes. Benefits in SRE reduction occurred with bisphosphonates and denosumab, however when compared, denosumab was superior. Denosumab however is not more cost effective, and multiple trials support potential de-escalation to either 12 weekly dosing or other reduced duration.Summary: There is a large body of evidence to support the role of BMAs in reducing SREs in metastatic breast and mCRPC. Impact on survival outcomes is heterogeneous, and future large database trials would be helpful in identifying which subgroups of patients truly have survival benefit from BMAs.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":"117-129"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0