Journal of Periodontal and Implant Science最新文献

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Clinical evaluation of Laser-Assisted New Attachment Procedure® (LANAP®) surgical treatment of chronic periodontitis: a retrospective case series of 1-year results in 22 consecutive patients. 激光辅助新附着手术®(LANAP®)治疗慢性牙周炎的临床评价:22例连续患者1年的回顾性病例系列。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-06-01 DOI: 10.5051/jpis.2202580129
Raymond A Yukna
{"title":"Clinical evaluation of Laser-Assisted New Attachment Procedure<sup>®</sup> (LANAP<sup>®</sup>) surgical treatment of chronic periodontitis: a retrospective case series of 1-year results in 22 consecutive patients.","authors":"Raymond A Yukna","doi":"10.5051/jpis.2202580129","DOIUrl":"https://doi.org/10.5051/jpis.2202580129","url":null,"abstract":"<p><strong>Purpose: </strong>Treatment for periodontitis has evolved over the years as new technologies have become available. Currently, lasers seem attractive as a treatment modality, but their effectiveness needs to be verified. The purpose of this project was to evaluate Laser Assisted New Attachment Procedure<sup>®</sup> (LANAP<sup>®</sup>) surgery as a single treatment modality.</p><p><strong>Methods: </strong>As part of a mandatory training program for periodontists and other dentists, 22 consecutive patients diagnosed with moderate to severe periodontitis (probing depth [PD] up to 11 mm) were treated with the LANAP<sup>®</sup> surgical approach using a 1064-nm Nd:YAG laser as part of a multi-step protocol. Following single-session active therapy, they were entered into a maintenance program. Their clinical status was re-evaluated at 12-18 months following surgery.</p><p><strong>Results: </strong>All 22 patients completed the 12- to 18-month follow-up. PD, clinical attachment level, and furcation (FURC) showed substantial improvement. Recession was minimal (mean, 0.1 mm), while 93.5% of PD measurements were 3 mm or less at re-evaluation. Furthermore, 40% of grade 2 FURC closed clinically.</p><p><strong>Conclusions: </strong>Within the limits of this case series, LANAP<sup>®</sup> was found to be an effective, minimally invasive, laser surgical therapy for moderate to advanced periodontitis.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/33/1b/jpis-53-173.PMC10315259.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10107618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Sinus augmentation with poly(ε)caprolactone-β tricalcium phosphate scaffolds, mesenchymal stem cells and platelet rich plasma for one-stage dental implantation in minipigs. 聚(ε)己内酯-β磷酸三钙支架、间充质干细胞和富血小板血浆在小型猪一期牙种植中的应用
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-06-01 DOI: 10.5051/jpis.2300660033
Jeong-Hun Nam, Akram Abdo Almansoori, Oh-Jun Kwon, Young-Kwon Seo, Bongju Kim, Young-Kyun Kim, Jong-Ho Lee, KangMi Pang
{"title":"Sinus augmentation with poly(ε)caprolactone-β tricalcium phosphate scaffolds, mesenchymal stem cells and platelet rich plasma for one-stage dental implantation in minipigs.","authors":"Jeong-Hun Nam,&nbsp;Akram Abdo Almansoori,&nbsp;Oh-Jun Kwon,&nbsp;Young-Kwon Seo,&nbsp;Bongju Kim,&nbsp;Young-Kyun Kim,&nbsp;Jong-Ho Lee,&nbsp;KangMi Pang","doi":"10.5051/jpis.2300660033","DOIUrl":"https://doi.org/10.5051/jpis.2300660033","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluated the efficacy of a tube-shaped poly(ε) caprolactone - β tricalcium phosphate (PCL-TCP) scaffold with the incorporation of human umbilical cord-derived mesenchymal stem cells (hUCMSCs) and platelet-rich plasma (PRP) for bone regeneration in the procedure of single-stage sinus augmentation and dental implantation in minipigs.</p><p><strong>Methods: </strong>Implants were placed in the bilateral sides of the maxillary sinuses of 5 minipigs and allocated to a PCL-TCP+hUCMSCs+PRP group (n=5), a PCL-TCP+PRP group (n=5), and a PCL-TCP-only group (n=6). After 12 weeks, bone regeneration was evaluated with soft X-rays, micro-computed tomography, fluorescence microscopy, and histomorphometric analysis.</p><p><strong>Results: </strong>Four implants failed (2 each in the PCL-TCP+hUCMSCs+PRP and PCL-TCP+hUCMSC groups). An analysis of the grayscale levels and bone-implant contact ratio showed significantly higher mean values in the PCL-TCP+hUCMSCs+PRP than in the PCL-TCP group (<i>P</i>=0.045 and <i>P</i>=0.016, respectively). In fluoromicroscopic images, new bone formation around the outer surfaces of the scaffolds was observed in the PCL-TCP+hUCMSCs+PRP group, suggesting a tenting effect of the specially designed scaffolds. Bone regeneration at the scaffold-implant interfaces was observed in all 3 groups.</p><p><strong>Conclusions: </strong>Using a tube-shaped, honeycombed PCL-TCP scaffold with hUCMSCs and PRP may serve to enhance bone formation and dental implants' osseointegration in the procedure of simultaneous sinus lifting and dental implantation.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b2/7e/jpis-53-218.PMC10315254.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9752630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Repeated irradiation by light-emitting diodes may impede the spontaneous progression of experimental periodontitis: a preclinical study. 发光二极管的反复照射可能阻碍实验性牙周炎的自发进展:一项临床前研究。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-04-01 DOI: 10.5051/jpis.2202320116
Hyemee Suh, Jungwon Lee, Sun-Hee Ahn, Woosub Song, Ling Li, Yong-Moo Lee, Yang-Jo Seol, Ki-Tae Koo
{"title":"Repeated irradiation by light-emitting diodes may impede the spontaneous progression of experimental periodontitis: a preclinical study.","authors":"Hyemee Suh,&nbsp;Jungwon Lee,&nbsp;Sun-Hee Ahn,&nbsp;Woosub Song,&nbsp;Ling Li,&nbsp;Yong-Moo Lee,&nbsp;Yang-Jo Seol,&nbsp;Ki-Tae Koo","doi":"10.5051/jpis.2202320116","DOIUrl":"https://doi.org/10.5051/jpis.2202320116","url":null,"abstract":"<p><strong>Purpose: </strong>We investigated whether repeated irradiation with light-emitting diodes (LEDs) at a combination of 470 nm and 525 nm could suppress the progression of experimental periodontitis.</p><p><strong>Methods: </strong>A experimental periodontitis model was established in the second, third, and fourth premolars of the mandible in beagle dogs for 2 months. The spontaneous progression of periodontitis was monitored under the specified treatment regimen for 3 months. During this period, the animals were subjected to treatments of either plaque control only (control) or plaque control with LED application (test) at 2-week intervals. The clinical parameters included the probing pocket depth (PPD), gingival recession (GR), and the clinical attachment level (CAL). Histomorphometric analysis was performed using measurements of the length of the junctional epithelium, connective tissue (CT) zone, and total soft tissue (ST).</p><p><strong>Results: </strong>There were significant differences in PPD between the control and test groups at baseline and 12 weeks. When the change in PPD was stratified based on time intervals, it was shown that greater differences occurred in the test group, with statistical significance for baseline to 12 weeks, 6 to 12 weeks, and baseline to 6 weeks. There was no significant difference in GR between the control and test groups at any time points. Likewise, no statistically significant differences were found in GR at any time intervals. CAL showed a statistically significant difference between the control and test groups at baseline only, although significant differences in CAL were observed between baseline and 12 weeks and between 6 and 12 weeks. The proportion of CT to ST was smaller for both buccal and lingual areas in the control group than in the test group.</p><p><strong>Conclusions: </strong>Repeated LED irradiation with a combination of 470-nm and 525-nm wavelengths may help suppress the progression of periodontal disease.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/18/e9/jpis-53-120.PMC10133817.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9728936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The socket shield technique and its complications, implant survival rate, and clinical outcomes: a systematic review. 套窝保护技术及其并发症,种植体存活率和临床结果:系统回顾。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-04-01 DOI: 10.5051/jpis.2201780089
Stefano Oliva, Mario Capogreco, Giovanna Murmura, Ettore Lupi, Di Carlo Mariachiara, Maurizio D'Amario
{"title":"The socket shield technique and its complications, implant survival rate, and clinical outcomes: a systematic review.","authors":"Stefano Oliva,&nbsp;Mario Capogreco,&nbsp;Giovanna Murmura,&nbsp;Ettore Lupi,&nbsp;Di Carlo Mariachiara,&nbsp;Maurizio D'Amario","doi":"10.5051/jpis.2201780089","DOIUrl":"https://doi.org/10.5051/jpis.2201780089","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this systematic review was to evaluate the effectiveness of the socket shield technique (SST), an innovative surgical method introduced in 2010, for reducing buccal bone plate resorption.</p><p><strong>Methods: </strong>The review was conducted following the PRISMA guidelines. Clinical studies conducted in humans and investigating the SST were searched on PubMed (MEDLINE), Embase, Web of Knowledge, and Google Scholar in November and December 2021. The implant survival rate, percentage of complications, and clinical parameters (marginal bone loss [MBL], pink esthetic score [PES], and buccal bone plate resorption [BBPR]) were analyzed using the collected data.</p><p><strong>Results: </strong>The initial search resulted in 132 articles. After article screening, the full texts of 19 studies were read and 17 articles were finally included in the review. In total, 656 implants were installed with the SST. Nine of the 656 implants experienced failure, resulting in an implant survival rate of 98.6%. The percentage of complications was about 3.81%. The analysis of clinical parameters (MBL, PES, and BBPR), showed favorable results for the SST. The mean MBL in implants placed with the SST was 0.39±0.28 mm versus 1.00±0.55 mm in those placed without the SST. PES had a better outcome in the SST group, with an average of 12.08±1.18 versus 10.77±0.74. BBPR had more favorable results in implants placed with the SST (0.32±0.10 mm) than in implants placed with the standard technique (1.05±0.18 mm).</p><p><strong>Conclusions: </strong>The SST could be considered beneficial for preserving the buccal bone plate. However, since only 7 of the included studies were long-term randomized controlled trials comparing the SST with the standard implant placement technique, the conclusions drawn from this systematic review should be interpreted with caution.</p><p><strong>Trial registration: </strong>PROSPERO Identifier: CRD42020180637.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/73/8e/jpis-53-99.PMC10133821.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9359121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Exploration of the relationship between periodontal disease and skin disease in honor of Gum Day. 探索牙周病与皮肤病的关系,以纪念牙龈日。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-04-01 DOI: 10.5051/jpis.235302edi01
Ji Hyun Lee, Jun-Beom Park
{"title":"Exploration of the relationship between periodontal disease and skin disease in honor of Gum Day.","authors":"Ji Hyun Lee,&nbsp;Jun-Beom Park","doi":"10.5051/jpis.235302edi01","DOIUrl":"https://doi.org/10.5051/jpis.235302edi01","url":null,"abstract":"working with regional public health departments to carry out prevention-focused initiatives as part of a goal to raise public awareness of periodontal disease [1]. The link between systemic disease and periodontitis has been explored in previous studies [2,3]. Moreover, national health management programs relating to noncommunicable and periodontal diseases have established a new model of a disease management system [4]. In honor of the 15th annual Gum Day, we would like to report that the presence of periodontal disease increases the incidence of psoriasis, and furthermore, smoking increases the incidence rate of psoriasis by 27% [5]. As a relatively early example of research linking oral health to dermatologic conditions, a study published in 2007 reported that gingivitis was found in 30% of patients with resistant atopic dermatitis, which improved after gingivitis treatment [6].","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d1/0d/jpis-53-97.PMC10133819.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9360458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective analysis of keratinized tissue augmentation using a xenogeneic collagen matrix for resolving peri-implant mucositis and peri-implantitis. 采用异种胶原基质治疗种植体周围黏膜炎和种植体周围炎的回顾性分析。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-04-01 DOI: 10.5051/jpis.2200700035
Jung Soo Park, Yeek Herr, Jong-Hyuk Chung, Seung-Il Shin, Hyun-Chang Lim
{"title":"Retrospective analysis of keratinized tissue augmentation using a xenogeneic collagen matrix for resolving peri-implant mucositis and peri-implantitis.","authors":"Jung Soo Park,&nbsp;Yeek Herr,&nbsp;Jong-Hyuk Chung,&nbsp;Seung-Il Shin,&nbsp;Hyun-Chang Lim","doi":"10.5051/jpis.2200700035","DOIUrl":"https://doi.org/10.5051/jpis.2200700035","url":null,"abstract":"<p><strong>Purpose: </strong>The significance of keratinized tissue for peri-implant health has been emphasized. However, there is an absence of clinical evidence for the use of a xenogeneic collagen matrix (XCM) to manage peri-implant mucositis and peri-implantitis. Therefore, the purpose of this study was to investigate outcomes after keratinized tissue augmentation using an XCM for the management of peri-implant diseases.</p><p><strong>Methods: </strong>Twelve implants (5 with peri-implant mucositis and 7 with peri-implantitis) in 10 patients were included in this study. Non-surgical treatments were first performed, but inflammation persisted in all implant sites. The implant sites all showed a lack of keratinized mucosa (KM) and vestibular depth (VD). Apically positioned flaps with XCM application were performed. Bone augmentation was simultaneously performed on peri-implantitis sites with an intrabony defect (>3 mm). The following clinical parameters were measured: the probing pocket depth (PPD), modified sulcular bleeding index (mSBI), suppuration (SUP), keratinized mucosal height (KMH), and VD.</p><p><strong>Results: </strong>There were no adverse healing events during the follow-up visits (18±4.6 months). The final KMHs and VDs were 4.34±0.86 mm and 8.0±4.05 mm, respectively, for the sites with peri-implant mucositis and 3.29±0.86 mm and 6.5±1.91 mm, respectively, for the sites with peri-implantitis. Additionally, the PPD and mSBI significantly decreased, and none of the implants presented with SUP.</p><p><strong>Conclusions: </strong>Keratinized tissue augmentation using an XCM for sites with peri-implant mucositis and peri-implantitis was effective for increasing the KMH and VD and decreasing peri-implant inflammation.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/61/ae/jpis-53-145.PMC10133816.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9359122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A retrospective epidemiological investigation of periodontitis risk and current smoking status based on the number of cigarettes per day and the Fagerström Test for Nicotine Dependence: a preliminary pilot study. 基于每天吸烟数量和Fagerström尼古丁依赖测试的牙周炎风险和当前吸烟状况的回顾性流行病学调查:一项初步试点研究。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-04-01 DOI: 10.5051/jpis.2202560128
Ji-Hoo Han, Seong-Nyum Jeong, Jae-Hong Lee
{"title":"A retrospective epidemiological investigation of periodontitis risk and current smoking status based on the number of cigarettes per day and the Fagerström Test for Nicotine Dependence: a preliminary pilot study.","authors":"Ji-Hoo Han,&nbsp;Seong-Nyum Jeong,&nbsp;Jae-Hong Lee","doi":"10.5051/jpis.2202560128","DOIUrl":"https://doi.org/10.5051/jpis.2202560128","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to investigate the risk of periodontitis according to current smoking status based on the number of cigarettes smoked per day (CPD) and the Fagerström Test for Nicotine Dependence (FTND).</p><p><strong>Methods: </strong>All enrolled patients were diagnosed and classified according to the new periodontal classification scheme, and current smoking status was investigated via a self-reported questionnaire. The correlation between smoking status (CPD and FTND) and periodontitis risk (severity of periodontitis and tooth loss due to periodontal reasons) was statistically assessed using Spearman correlation coefficients. Moreover, partial correlation analyses between smoking and periodontal status were performed after adjusting for age, sex, and diabetes mellitus.</p><p><strong>Results: </strong>Overall, data from 74 men and 16 women (mean age: 48.1±10.8 years) were evaluated. The mean number of missing teeth, CPD, and FTND score were 3.5±5.2, 24.6±15.5, and 3.5±2, respectively. CPD and the FTND were significantly positively correlated with each other (<i>r</i>=0.741, <i>P</i><0.001). CPD and the FTND were also significantly correlated with the severity of periodontitis (CPD: <i>r</i>=0.457, <i>P</i><0.05 and FTND: <i>r</i>=0.326, <i>P</i><0.05) and the number of missing teeth due to periodontal reasons (CPD: <i>r</i>=0.525, <i>P</i><0.05 and FTND: <i>r</i>=0.480, <i>P</i><0.05), respectively.</p><p><strong>Conclusions: </strong>Within the limitations of this study, both CPD and the FTND were significantly correlated with the severity of periodontitis and the number of periodontally compromised extracted teeth.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2b/77/jpis-53-135.PMC10133818.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9728934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro investigation of the antibacterial and anti-inflammatory effects of LED irradiation. LED辐照抗菌抗炎作用的体外研究。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-04-01 DOI: 10.5051/jpis.2200920046
Jungwon Lee, Hyun-Yong Song, Sun-Hee Ahn, Woosub Song, Yang-Jo Seol, Yong-Moo Lee, Ki-Tae Koo
{"title":"<i>In vitro</i> investigation of the antibacterial and anti-inflammatory effects of LED irradiation.","authors":"Jungwon Lee,&nbsp;Hyun-Yong Song,&nbsp;Sun-Hee Ahn,&nbsp;Woosub Song,&nbsp;Yang-Jo Seol,&nbsp;Yong-Moo Lee,&nbsp;Ki-Tae Koo","doi":"10.5051/jpis.2200920046","DOIUrl":"https://doi.org/10.5051/jpis.2200920046","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the proper wavelengths for safe levels of light-emitting diode (LED) irradiation with bactericidal and photobiomodulation effects <i>in vitro</i>.</p><p><strong>Methods: </strong>Cell viability tests of fibroblasts and osteoblasts after LED irradiation at 470, 525, 590, 630, and 850 nm were performed using the thiazolyl blue tetrazolium bromide assay. The bactericidal effect of 470-nm LED irradiation was analyzed with <i>Streptococcus gordonii</i>, <i>Aggregatibacter actinomycetemcomitans</i>, <i>Fusobacterium nucleatum</i>, <i>Porphyromonas gingivalis</i>, and <i>Tannerella forsythia</i>. Levels of nitric oxide, a proinflammatory mediator, were measured to identify the anti-inflammatory effect of LED irradiation on lipopolysaccharide-stimulated inflammation in RAW 264.7 macrophages.</p><p><strong>Results: </strong>LED irradiation at wavelengths of 470, 525, 590, 630, and 850 nm showed no cytotoxic effect on fibroblasts and osteoblasts. LED irradiation at 630 and 850 nm led to fibroblast proliferation compared to no LED irradiation. LED irradiation at 470 nm resulted in bactericidal effects on <i>S. gordonii</i>, <i>A. actinomycetemcomitans</i>, <i>F. nucleatum</i>, <i>P. gingivalis</i>, and <i>T. forsythia.</i> Lipopolysaccharide (LPS)-induced RAW 264.7 inflammation was reduced by irradiation with 525-nm LED before LPS treatment and irradiation with 630-nm LED after LPS treatment; however, the effects were limited.</p><p><strong>Conclusions: </strong>LED irradiation at 470 nm showed bactericidal effects, while LED irradiation at 525 and 630 nm showed preventive and treatment effects on LPS-induced RAW 264.7 inflammation. The application of LED irradiation has potential as an adjuvant in periodontal therapy, although further investigations should be performed <i>in vivo</i>.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/57/a3/jpis-53-110.PMC10133822.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9359123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The impact of polydeoxyribonucleotide on early bone formation in lateral-window sinus floor elevation with simultaneous implant placement. 多脱氧核糖核酸对侧窗窦底抬高同时植入早期骨形成的影响。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-04-01 DOI: 10.5051/jpis.2202760138
Dongseob Lee, Jungwon Lee, Ki-Tae Koo, Yang-Jo Seol, Yong-Moo Lee
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引用次数: 4
The Korean Academy of Periodontology's focus on national promotion projects for periodontal health. 韩国牙周病学会专注于牙周健康的国家促进项目。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-02-01 DOI: 10.5051/jpis.235301edi01
Seung-Beom Kye
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引用次数: 1
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