{"title":"Dental education now and in the future.","authors":"Jae Il Lee","doi":"10.5051/jpis.235303edi01","DOIUrl":"https://doi.org/10.5051/jpis.235303edi01","url":null,"abstract":"Dentistry has consistently maintained a strong connection with technological advancements. Dental education has incorporated technology to enrich both teaching and learning experiences. This involves training students on the effective use of virtual reality simulations, digital imaging, 3D printing, and digital tools like intraoral scanners. These technologies offer students more interactive and immersive learning opportunities. Integrating these tools into the curriculum enhances diagnostic capabilities, treatment planning, and patient management.","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 3","pages":"171-172"},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/11/a2/jpis-53-171.PMC10315257.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9741776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MinKee Son, Yuri Song, Yeuni Yu, Si Yeong Kim, Jung-Bo Huh, Eun-Bin Bae, Won-Tak Cho, Hee Sam Na, Jin Chung
{"title":"The oral microbiome of implant-abutment screw holes compared with the peri-implant sulcus and natural supragingival plaque in healthy individuals.","authors":"MinKee Son, Yuri Song, Yeuni Yu, Si Yeong Kim, Jung-Bo Huh, Eun-Bin Bae, Won-Tak Cho, Hee Sam Na, Jin Chung","doi":"10.5051/jpis.2300100005","DOIUrl":"https://doi.org/10.5051/jpis.2300100005","url":null,"abstract":"<p><strong>Purpose: </strong>An implant-supported prosthesis consists of an implant fixture, an abutment, an internal screw that connects the abutment to the implant fixture, and the upper prosthesis. Numerous studies have investigated the microorganisms present on the implant surface, surrounding tissues, and the subgingival microflora associated with peri-implantitis. However, there is limited information regarding the microbiome within the internal screw space. In this study, microbial samples were collected from the supragingival surfaces of natural teeth, the peri-implant sulcus, and the implant-abutment screw hole, in order to characterize the microbiome of the internal screw space in healthy subjects.</p><p><strong>Methods: </strong>Samples were obtained from the supragingival region of natural teeth, the peri-implant sulcus, and the implant screw hole in 20 healthy subjects. DNA was extracted, and the V3-V4 region of the 16S ribosomal RNA was sequenced for microbiome analysis. Alpha diversity, beta diversity, linear discriminant analysis effect size (LEfSe), and network analysis were employed to compare the characteristics of the microbiomes.</p><p><strong>Results: </strong>We observed significant differences in beta diversity among the samples. Upon analyzing the significant taxa using LEfSe, the microbial composition of the implant-abutment screw hole's microbiome was found to be similar to that of the other sampling sites' microbiomes. Moreover, the microbiome network analysis revealed a unique network complexity in samples obtained from the implant screw hole compared to those from the other sampling sites.</p><p><strong>Conclusions: </strong>The bacterial composition of the biofilm collected from the implant-abutment screw hole exhibited significant differences compared to the supra-structure of the implant. Therefore, long-term monitoring and management of not only the peri-implant tissue but also the implant screw are necessary.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 3","pages":"233-244"},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a7/3a/jpis-53-233.PMC10315253.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9747402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ki-Yeol Park, Min-Ho Kim, Seong-Ho Choi, Eun-Kyoung Pang
{"title":"Association of periodontitis with menopause and hormone replacement therapy: a hospital cohort study using a common data model.","authors":"Ki-Yeol Park, Min-Ho Kim, Seong-Ho Choi, Eun-Kyoung Pang","doi":"10.5051/jpis.2202480124","DOIUrl":"https://doi.org/10.5051/jpis.2202480124","url":null,"abstract":"<p><strong>Purpose: </strong>The present study was designed to compare the incidence of periodontitis according to menopausal status and to investigate the possible effect of hormone replacement therapy (HRT) on periodontitis in postmenopausal women using a common data model (CDM) at a single institution.</p><p><strong>Methods: </strong>This study involved retrospective cohort data of 950,751 patients from a 20-year database (2001 to 2020) of Ewha Womans University Mokdong Hospital converted to the Observational Medical Outcomes Partnership CDM. One-way analysis of variance models and the χ² test were used to analyze the statistical differences in patient characteristics among groups. A time-dependent Cox regression analysis was used to calculate hazard ratios and 95% confidence intervals, and <i>P</i> values less than 0.05 were considered to indicate statistical significance.</p><p><strong>Results: </strong>Of the 29,729 patients, 1,307 patients were diagnosed with periodontitis and 28,422 patients were not. Periodontitis was significantly more common among postmenopausal patients regardless of HRT status than among the non-menopausal group (<i>P</i><0.05). Time-dependent Cox regression analysis showed that the postmenopausal patients had a significantly higher chance of having periodontitis than non-menopausal patients (<i>P</i><0.05), but after adjustment for age, body mass index, and smoking status, the difference between the non-menopausal and post-menopausal HRT-treated groups was insignificant (<i>P</i>=0.140).</p><p><strong>Conclusions: </strong>Postmenopausal women had a significantly greater risk of periodontitis than non-menopausal women. Additionally, the use of HRT in postmenopausal women could reduce the incidence of periodontitis.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 3","pages":"184-193"},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/94/9c/jpis-53-184.PMC10315258.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9803749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiang Jin, Jin-Young Park, Jung-Seok Lee, Ui-Won Jung, Seong-Ho Choi, Jae-Kook Cha
{"title":"Tissue integration patterns of non-crosslinked and crosslinked collagen membranes: an experimental <i>in vivo</i> study.","authors":"Xiang Jin, Jin-Young Park, Jung-Seok Lee, Ui-Won Jung, Seong-Ho Choi, Jae-Kook Cha","doi":"10.5051/jpis.2203260163","DOIUrl":"https://doi.org/10.5051/jpis.2203260163","url":null,"abstract":"<p><strong>Purpose: </strong>Non-crosslinked and crosslinked collagen membranes are known to exhibit distinct degradation characteristics, resulting in contrasting orientations of the adjacent tissues and different biological processes. The aim of this study was to conduct a histomorphometric assessment of non-crosslinked and crosslinked collagen membranes regarding neovascularization, tissue integration, tissue encapsulation, and biodegradation.</p><p><strong>Methods: </strong>Guided bone regeneration was performed using either a non-crosslinked (BG) or a crosslinked collagen membrane (CM) in 15 beagle dogs, which were euthanized at 4, 8, and 16 weeks (n=5 each) for histomorphometric analysis. The samples were assessed regarding neovascularization, tissue integration, encapsulation, the remaining membrane area, and pseudoperiosteum formation. The BG and CM groups were compared at different time periods using nonparametric statistical methods.</p><p><strong>Results: </strong>The remaining membrane area of CM was significantly greater than that of BG at 16 weeks; however, there were no significant differences at 4 and 8 weeks. Conversely, the neovascularization score for CM was significantly less than that for BG at 16 weeks. BG exhibited significantly greater tissue integration and encapsulation scores than CM at all time periods, apart from encapsulation at 16 weeks. Pseudoperiosteum formation was observed in the BG group at 16 weeks.</p><p><strong>Conclusions: </strong>Although BG membranes were more rapidly biodegraded than CM membranes, they were gradually replaced by connective tissue with complete integration and maturation of the surrounding tissues to form dense periosteum-like connective tissue. Further studies need to be performed to validate the barrier effect of the pseudoperiosteum.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 3","pages":"207-217"},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/37/6a/jpis-53-207.PMC10315255.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10107621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical evaluation of Laser-Assisted New Attachment Procedure<sup>®</sup> (LANAP<sup>®</sup>) surgical treatment of chronic periodontitis: a retrospective case series of 1-year results in 22 consecutive patients.","authors":"Raymond A Yukna","doi":"10.5051/jpis.2202580129","DOIUrl":"https://doi.org/10.5051/jpis.2202580129","url":null,"abstract":"<p><strong>Purpose: </strong>Treatment for periodontitis has evolved over the years as new technologies have become available. Currently, lasers seem attractive as a treatment modality, but their effectiveness needs to be verified. The purpose of this project was to evaluate Laser Assisted New Attachment Procedure<sup>®</sup> (LANAP<sup>®</sup>) surgery as a single treatment modality.</p><p><strong>Methods: </strong>As part of a mandatory training program for periodontists and other dentists, 22 consecutive patients diagnosed with moderate to severe periodontitis (probing depth [PD] up to 11 mm) were treated with the LANAP<sup>®</sup> surgical approach using a 1064-nm Nd:YAG laser as part of a multi-step protocol. Following single-session active therapy, they were entered into a maintenance program. Their clinical status was re-evaluated at 12-18 months following surgery.</p><p><strong>Results: </strong>All 22 patients completed the 12- to 18-month follow-up. PD, clinical attachment level, and furcation (FURC) showed substantial improvement. Recession was minimal (mean, 0.1 mm), while 93.5% of PD measurements were 3 mm or less at re-evaluation. Furthermore, 40% of grade 2 FURC closed clinically.</p><p><strong>Conclusions: </strong>Within the limits of this case series, LANAP<sup>®</sup> was found to be an effective, minimally invasive, laser surgical therapy for moderate to advanced periodontitis.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 3","pages":"173-183"},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/33/1b/jpis-53-173.PMC10315259.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10107618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeong-Hun Nam, Akram Abdo Almansoori, Oh-Jun Kwon, Young-Kwon Seo, Bongju Kim, Young-Kyun Kim, Jong-Ho Lee, KangMi Pang
{"title":"Sinus augmentation with poly(ε)caprolactone-β tricalcium phosphate scaffolds, mesenchymal stem cells and platelet rich plasma for one-stage dental implantation in minipigs.","authors":"Jeong-Hun Nam, Akram Abdo Almansoori, Oh-Jun Kwon, Young-Kwon Seo, Bongju Kim, Young-Kyun Kim, Jong-Ho Lee, KangMi Pang","doi":"10.5051/jpis.2300660033","DOIUrl":"https://doi.org/10.5051/jpis.2300660033","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluated the efficacy of a tube-shaped poly(ε) caprolactone - β tricalcium phosphate (PCL-TCP) scaffold with the incorporation of human umbilical cord-derived mesenchymal stem cells (hUCMSCs) and platelet-rich plasma (PRP) for bone regeneration in the procedure of single-stage sinus augmentation and dental implantation in minipigs.</p><p><strong>Methods: </strong>Implants were placed in the bilateral sides of the maxillary sinuses of 5 minipigs and allocated to a PCL-TCP+hUCMSCs+PRP group (n=5), a PCL-TCP+PRP group (n=5), and a PCL-TCP-only group (n=6). After 12 weeks, bone regeneration was evaluated with soft X-rays, micro-computed tomography, fluorescence microscopy, and histomorphometric analysis.</p><p><strong>Results: </strong>Four implants failed (2 each in the PCL-TCP+hUCMSCs+PRP and PCL-TCP+hUCMSC groups). An analysis of the grayscale levels and bone-implant contact ratio showed significantly higher mean values in the PCL-TCP+hUCMSCs+PRP than in the PCL-TCP group (<i>P</i>=0.045 and <i>P</i>=0.016, respectively). In fluoromicroscopic images, new bone formation around the outer surfaces of the scaffolds was observed in the PCL-TCP+hUCMSCs+PRP group, suggesting a tenting effect of the specially designed scaffolds. Bone regeneration at the scaffold-implant interfaces was observed in all 3 groups.</p><p><strong>Conclusions: </strong>Using a tube-shaped, honeycombed PCL-TCP scaffold with hUCMSCs and PRP may serve to enhance bone formation and dental implants' osseointegration in the procedure of simultaneous sinus lifting and dental implantation.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 3","pages":"218-232"},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b2/7e/jpis-53-218.PMC10315254.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9752630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Repeated irradiation by light-emitting diodes may impede the spontaneous progression of experimental periodontitis: a preclinical study.","authors":"Hyemee Suh, Jungwon Lee, Sun-Hee Ahn, Woosub Song, Ling Li, Yong-Moo Lee, Yang-Jo Seol, Ki-Tae Koo","doi":"10.5051/jpis.2202320116","DOIUrl":"https://doi.org/10.5051/jpis.2202320116","url":null,"abstract":"<p><strong>Purpose: </strong>We investigated whether repeated irradiation with light-emitting diodes (LEDs) at a combination of 470 nm and 525 nm could suppress the progression of experimental periodontitis.</p><p><strong>Methods: </strong>A experimental periodontitis model was established in the second, third, and fourth premolars of the mandible in beagle dogs for 2 months. The spontaneous progression of periodontitis was monitored under the specified treatment regimen for 3 months. During this period, the animals were subjected to treatments of either plaque control only (control) or plaque control with LED application (test) at 2-week intervals. The clinical parameters included the probing pocket depth (PPD), gingival recession (GR), and the clinical attachment level (CAL). Histomorphometric analysis was performed using measurements of the length of the junctional epithelium, connective tissue (CT) zone, and total soft tissue (ST).</p><p><strong>Results: </strong>There were significant differences in PPD between the control and test groups at baseline and 12 weeks. When the change in PPD was stratified based on time intervals, it was shown that greater differences occurred in the test group, with statistical significance for baseline to 12 weeks, 6 to 12 weeks, and baseline to 6 weeks. There was no significant difference in GR between the control and test groups at any time points. Likewise, no statistically significant differences were found in GR at any time intervals. CAL showed a statistically significant difference between the control and test groups at baseline only, although significant differences in CAL were observed between baseline and 12 weeks and between 6 and 12 weeks. The proportion of CT to ST was smaller for both buccal and lingual areas in the control group than in the test group.</p><p><strong>Conclusions: </strong>Repeated LED irradiation with a combination of 470-nm and 525-nm wavelengths may help suppress the progression of periodontal disease.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 2","pages":"120-134"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/18/e9/jpis-53-120.PMC10133817.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9728936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefano Oliva, Mario Capogreco, Giovanna Murmura, Ettore Lupi, Di Carlo Mariachiara, Maurizio D'Amario
{"title":"The socket shield technique and its complications, implant survival rate, and clinical outcomes: a systematic review.","authors":"Stefano Oliva, Mario Capogreco, Giovanna Murmura, Ettore Lupi, Di Carlo Mariachiara, Maurizio D'Amario","doi":"10.5051/jpis.2201780089","DOIUrl":"https://doi.org/10.5051/jpis.2201780089","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this systematic review was to evaluate the effectiveness of the socket shield technique (SST), an innovative surgical method introduced in 2010, for reducing buccal bone plate resorption.</p><p><strong>Methods: </strong>The review was conducted following the PRISMA guidelines. Clinical studies conducted in humans and investigating the SST were searched on PubMed (MEDLINE), Embase, Web of Knowledge, and Google Scholar in November and December 2021. The implant survival rate, percentage of complications, and clinical parameters (marginal bone loss [MBL], pink esthetic score [PES], and buccal bone plate resorption [BBPR]) were analyzed using the collected data.</p><p><strong>Results: </strong>The initial search resulted in 132 articles. After article screening, the full texts of 19 studies were read and 17 articles were finally included in the review. In total, 656 implants were installed with the SST. Nine of the 656 implants experienced failure, resulting in an implant survival rate of 98.6%. The percentage of complications was about 3.81%. The analysis of clinical parameters (MBL, PES, and BBPR), showed favorable results for the SST. The mean MBL in implants placed with the SST was 0.39±0.28 mm versus 1.00±0.55 mm in those placed without the SST. PES had a better outcome in the SST group, with an average of 12.08±1.18 versus 10.77±0.74. BBPR had more favorable results in implants placed with the SST (0.32±0.10 mm) than in implants placed with the standard technique (1.05±0.18 mm).</p><p><strong>Conclusions: </strong>The SST could be considered beneficial for preserving the buccal bone plate. However, since only 7 of the included studies were long-term randomized controlled trials comparing the SST with the standard implant placement technique, the conclusions drawn from this systematic review should be interpreted with caution.</p><p><strong>Trial registration: </strong>PROSPERO Identifier: CRD42020180637.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 2","pages":"99-109"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/73/8e/jpis-53-99.PMC10133821.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9359121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploration of the relationship between periodontal disease and skin disease in honor of Gum Day.","authors":"Ji Hyun Lee, Jun-Beom Park","doi":"10.5051/jpis.235302edi01","DOIUrl":"https://doi.org/10.5051/jpis.235302edi01","url":null,"abstract":"working with regional public health departments to carry out prevention-focused initiatives as part of a goal to raise public awareness of periodontal disease [1]. The link between systemic disease and periodontitis has been explored in previous studies [2,3]. Moreover, national health management programs relating to noncommunicable and periodontal diseases have established a new model of a disease management system [4]. In honor of the 15th annual Gum Day, we would like to report that the presence of periodontal disease increases the incidence of psoriasis, and furthermore, smoking increases the incidence rate of psoriasis by 27% [5]. As a relatively early example of research linking oral health to dermatologic conditions, a study published in 2007 reported that gingivitis was found in 30% of patients with resistant atopic dermatitis, which improved after gingivitis treatment [6].","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 2","pages":"97-98"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d1/0d/jpis-53-97.PMC10133819.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9360458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jung Soo Park, Yeek Herr, Jong-Hyuk Chung, Seung-Il Shin, Hyun-Chang Lim
{"title":"Retrospective analysis of keratinized tissue augmentation using a xenogeneic collagen matrix for resolving peri-implant mucositis and peri-implantitis.","authors":"Jung Soo Park, Yeek Herr, Jong-Hyuk Chung, Seung-Il Shin, Hyun-Chang Lim","doi":"10.5051/jpis.2200700035","DOIUrl":"https://doi.org/10.5051/jpis.2200700035","url":null,"abstract":"<p><strong>Purpose: </strong>The significance of keratinized tissue for peri-implant health has been emphasized. However, there is an absence of clinical evidence for the use of a xenogeneic collagen matrix (XCM) to manage peri-implant mucositis and peri-implantitis. Therefore, the purpose of this study was to investigate outcomes after keratinized tissue augmentation using an XCM for the management of peri-implant diseases.</p><p><strong>Methods: </strong>Twelve implants (5 with peri-implant mucositis and 7 with peri-implantitis) in 10 patients were included in this study. Non-surgical treatments were first performed, but inflammation persisted in all implant sites. The implant sites all showed a lack of keratinized mucosa (KM) and vestibular depth (VD). Apically positioned flaps with XCM application were performed. Bone augmentation was simultaneously performed on peri-implantitis sites with an intrabony defect (>3 mm). The following clinical parameters were measured: the probing pocket depth (PPD), modified sulcular bleeding index (mSBI), suppuration (SUP), keratinized mucosal height (KMH), and VD.</p><p><strong>Results: </strong>There were no adverse healing events during the follow-up visits (18±4.6 months). The final KMHs and VDs were 4.34±0.86 mm and 8.0±4.05 mm, respectively, for the sites with peri-implant mucositis and 3.29±0.86 mm and 6.5±1.91 mm, respectively, for the sites with peri-implantitis. Additionally, the PPD and mSBI significantly decreased, and none of the implants presented with SUP.</p><p><strong>Conclusions: </strong>Keratinized tissue augmentation using an XCM for sites with peri-implant mucositis and peri-implantitis was effective for increasing the KMH and VD and decreasing peri-implant inflammation.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 2","pages":"145-156"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/61/ae/jpis-53-145.PMC10133816.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9359122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}