Journal of Periodontal and Implant Science最新文献

{"title":"Repeated irradiation by light-emitting diodes may impede the spontaneous progression of experimental periodontitis: a preclinical study.","authors":"Hyemee Suh,&nbsp;Jungwon Lee,&nbsp;Sun-Hee Ahn,&nbsp;Woosub Song,&nbsp;Ling Li,&nbsp;Yong-Moo Lee,&nbsp;Yang-Jo Seol,&nbsp;Ki-Tae Koo","doi":"10.5051/jpis.2202320116","DOIUrl":"https://doi.org/10.5051/jpis.2202320116","url":null,"abstract":"<p><strong>Purpose: </strong>We investigated whether repeated irradiation with light-emitting diodes (LEDs) at a combination of 470 nm and 525 nm could suppress the progression of experimental periodontitis.</p><p><strong>Methods: </strong>A experimental periodontitis model was established in the second, third, and fourth premolars of the mandible in beagle dogs for 2 months. The spontaneous progression of periodontitis was monitored under the specified treatment regimen for 3 months. During this period, the animals were subjected to treatments of either plaque control only (control) or plaque control with LED application (test) at 2-week intervals. The clinical parameters included the probing pocket depth (PPD), gingival recession (GR), and the clinical attachment level (CAL). Histomorphometric analysis was performed using measurements of the length of the junctional epithelium, connective tissue (CT) zone, and total soft tissue (ST).</p><p><strong>Results: </strong>There were significant differences in PPD between the control and test groups at baseline and 12 weeks. When the change in PPD was stratified based on time intervals, it was shown that greater differences occurred in the test group, with statistical significance for baseline to 12 weeks, 6 to 12 weeks, and baseline to 6 weeks. There was no significant difference in GR between the control and test groups at any time points. Likewise, no statistically significant differences were found in GR at any time intervals. CAL showed a statistically significant difference between the control and test groups at baseline only, although significant differences in CAL were observed between baseline and 12 weeks and between 6 and 12 weeks. The proportion of CT to ST was smaller for both buccal and lingual areas in the control group than in the test group.</p><p><strong>Conclusions: </strong>Repeated LED irradiation with a combination of 470-nm and 525-nm wavelengths may help suppress the progression of periodontal disease.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 2","pages":"120-134"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/18/e9/jpis-53-120.PMC10133817.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9728936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The socket shield technique and its complications, implant survival rate, and clinical outcomes: a systematic review.","authors":"Stefano Oliva,&nbsp;Mario Capogreco,&nbsp;Giovanna Murmura,&nbsp;Ettore Lupi,&nbsp;Di Carlo Mariachiara,&nbsp;Maurizio D'Amario","doi":"10.5051/jpis.2201780089","DOIUrl":"https://doi.org/10.5051/jpis.2201780089","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this systematic review was to evaluate the effectiveness of the socket shield technique (SST), an innovative surgical method introduced in 2010, for reducing buccal bone plate resorption.</p><p><strong>Methods: </strong>The review was conducted following the PRISMA guidelines. Clinical studies conducted in humans and investigating the SST were searched on PubMed (MEDLINE), Embase, Web of Knowledge, and Google Scholar in November and December 2021. The implant survival rate, percentage of complications, and clinical parameters (marginal bone loss [MBL], pink esthetic score [PES], and buccal bone plate resorption [BBPR]) were analyzed using the collected data.</p><p><strong>Results: </strong>The initial search resulted in 132 articles. After article screening, the full texts of 19 studies were read and 17 articles were finally included in the review. In total, 656 implants were installed with the SST. Nine of the 656 implants experienced failure, resulting in an implant survival rate of 98.6%. The percentage of complications was about 3.81%. The analysis of clinical parameters (MBL, PES, and BBPR), showed favorable results for the SST. The mean MBL in implants placed with the SST was 0.39±0.28 mm versus 1.00±0.55 mm in those placed without the SST. PES had a better outcome in the SST group, with an average of 12.08±1.18 versus 10.77±0.74. BBPR had more favorable results in implants placed with the SST (0.32±0.10 mm) than in implants placed with the standard technique (1.05±0.18 mm).</p><p><strong>Conclusions: </strong>The SST could be considered beneficial for preserving the buccal bone plate. However, since only 7 of the included studies were long-term randomized controlled trials comparing the SST with the standard implant placement technique, the conclusions drawn from this systematic review should be interpreted with caution.</p><p><strong>Trial registration: </strong>PROSPERO Identifier: CRD42020180637.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 2","pages":"99-109"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/73/8e/jpis-53-99.PMC10133821.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9359121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploration of the relationship between periodontal disease and skin disease in honor of Gum Day.","authors":"Ji Hyun Lee,&nbsp;Jun-Beom Park","doi":"10.5051/jpis.235302edi01","DOIUrl":"https://doi.org/10.5051/jpis.235302edi01","url":null,"abstract":"working with regional public health departments to carry out prevention-focused initiatives as part of a goal to raise public awareness of periodontal disease [1]. The link between systemic disease and periodontitis has been explored in previous studies [2,3]. Moreover, national health management programs relating to noncommunicable and periodontal diseases have established a new model of a disease management system [4]. In honor of the 15th annual Gum Day, we would like to report that the presence of periodontal disease increases the incidence of psoriasis, and furthermore, smoking increases the incidence rate of psoriasis by 27% [5]. As a relatively early example of research linking oral health to dermatologic conditions, a study published in 2007 reported that gingivitis was found in 30% of patients with resistant atopic dermatitis, which improved after gingivitis treatment [6].","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 2","pages":"97-98"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d1/0d/jpis-53-97.PMC10133819.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9360458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective analysis of keratinized tissue augmentation using a xenogeneic collagen matrix for resolving peri-implant mucositis and peri-implantitis.","authors":"Jung Soo Park,&nbsp;Yeek Herr,&nbsp;Jong-Hyuk Chung,&nbsp;Seung-Il Shin,&nbsp;Hyun-Chang Lim","doi":"10.5051/jpis.2200700035","DOIUrl":"https://doi.org/10.5051/jpis.2200700035","url":null,"abstract":"<p><strong>Purpose: </strong>The significance of keratinized tissue for peri-implant health has been emphasized. However, there is an absence of clinical evidence for the use of a xenogeneic collagen matrix (XCM) to manage peri-implant mucositis and peri-implantitis. Therefore, the purpose of this study was to investigate outcomes after keratinized tissue augmentation using an XCM for the management of peri-implant diseases.</p><p><strong>Methods: </strong>Twelve implants (5 with peri-implant mucositis and 7 with peri-implantitis) in 10 patients were included in this study. Non-surgical treatments were first performed, but inflammation persisted in all implant sites. The implant sites all showed a lack of keratinized mucosa (KM) and vestibular depth (VD). Apically positioned flaps with XCM application were performed. Bone augmentation was simultaneously performed on peri-implantitis sites with an intrabony defect (>3 mm). The following clinical parameters were measured: the probing pocket depth (PPD), modified sulcular bleeding index (mSBI), suppuration (SUP), keratinized mucosal height (KMH), and VD.</p><p><strong>Results: </strong>There were no adverse healing events during the follow-up visits (18±4.6 months). The final KMHs and VDs were 4.34±0.86 mm and 8.0±4.05 mm, respectively, for the sites with peri-implant mucositis and 3.29±0.86 mm and 6.5±1.91 mm, respectively, for the sites with peri-implantitis. Additionally, the PPD and mSBI significantly decreased, and none of the implants presented with SUP.</p><p><strong>Conclusions: </strong>Keratinized tissue augmentation using an XCM for sites with peri-implant mucositis and peri-implantitis was effective for increasing the KMH and VD and decreasing peri-implant inflammation.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 2","pages":"145-156"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/61/ae/jpis-53-145.PMC10133816.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9359122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A retrospective epidemiological investigation of periodontitis risk and current smoking status based on the number of cigarettes per day and the Fagerström Test for Nicotine Dependence: a preliminary pilot study.","authors":"Ji-Hoo Han,&nbsp;Seong-Nyum Jeong,&nbsp;Jae-Hong Lee","doi":"10.5051/jpis.2202560128","DOIUrl":"https://doi.org/10.5051/jpis.2202560128","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to investigate the risk of periodontitis according to current smoking status based on the number of cigarettes smoked per day (CPD) and the Fagerström Test for Nicotine Dependence (FTND).</p><p><strong>Methods: </strong>All enrolled patients were diagnosed and classified according to the new periodontal classification scheme, and current smoking status was investigated via a self-reported questionnaire. The correlation between smoking status (CPD and FTND) and periodontitis risk (severity of periodontitis and tooth loss due to periodontal reasons) was statistically assessed using Spearman correlation coefficients. Moreover, partial correlation analyses between smoking and periodontal status were performed after adjusting for age, sex, and diabetes mellitus.</p><p><strong>Results: </strong>Overall, data from 74 men and 16 women (mean age: 48.1±10.8 years) were evaluated. The mean number of missing teeth, CPD, and FTND score were 3.5±5.2, 24.6±15.5, and 3.5±2, respectively. CPD and the FTND were significantly positively correlated with each other (<i>r</i>=0.741, <i>P</i><0.001). CPD and the FTND were also significantly correlated with the severity of periodontitis (CPD: <i>r</i>=0.457, <i>P</i><0.05 and FTND: <i>r</i>=0.326, <i>P</i><0.05) and the number of missing teeth due to periodontal reasons (CPD: <i>r</i>=0.525, <i>P</i><0.05 and FTND: <i>r</i>=0.480, <i>P</i><0.05), respectively.</p><p><strong>Conclusions: </strong>Within the limitations of this study, both CPD and the FTND were significantly correlated with the severity of periodontitis and the number of periodontally compromised extracted teeth.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 2","pages":"135-144"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2b/77/jpis-53-135.PMC10133818.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9728934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>In vitro</i> investigation of the antibacterial and anti-inflammatory effects of LED irradiation.","authors":"Jungwon Lee,&nbsp;Hyun-Yong Song,&nbsp;Sun-Hee Ahn,&nbsp;Woosub Song,&nbsp;Yang-Jo Seol,&nbsp;Yong-Moo Lee,&nbsp;Ki-Tae Koo","doi":"10.5051/jpis.2200920046","DOIUrl":"https://doi.org/10.5051/jpis.2200920046","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the proper wavelengths for safe levels of light-emitting diode (LED) irradiation with bactericidal and photobiomodulation effects <i>in vitro</i>.</p><p><strong>Methods: </strong>Cell viability tests of fibroblasts and osteoblasts after LED irradiation at 470, 525, 590, 630, and 850 nm were performed using the thiazolyl blue tetrazolium bromide assay. The bactericidal effect of 470-nm LED irradiation was analyzed with <i>Streptococcus gordonii</i>, <i>Aggregatibacter actinomycetemcomitans</i>, <i>Fusobacterium nucleatum</i>, <i>Porphyromonas gingivalis</i>, and <i>Tannerella forsythia</i>. Levels of nitric oxide, a proinflammatory mediator, were measured to identify the anti-inflammatory effect of LED irradiation on lipopolysaccharide-stimulated inflammation in RAW 264.7 macrophages.</p><p><strong>Results: </strong>LED irradiation at wavelengths of 470, 525, 590, 630, and 850 nm showed no cytotoxic effect on fibroblasts and osteoblasts. LED irradiation at 630 and 850 nm led to fibroblast proliferation compared to no LED irradiation. LED irradiation at 470 nm resulted in bactericidal effects on <i>S. gordonii</i>, <i>A. actinomycetemcomitans</i>, <i>F. nucleatum</i>, <i>P. gingivalis</i>, and <i>T. forsythia.</i> Lipopolysaccharide (LPS)-induced RAW 264.7 inflammation was reduced by irradiation with 525-nm LED before LPS treatment and irradiation with 630-nm LED after LPS treatment; however, the effects were limited.</p><p><strong>Conclusions: </strong>LED irradiation at 470 nm showed bactericidal effects, while LED irradiation at 525 and 630 nm showed preventive and treatment effects on LPS-induced RAW 264.7 inflammation. The application of LED irradiation has potential as an adjuvant in periodontal therapy, although further investigations should be performed <i>in vivo</i>.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 2","pages":"110-119"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/57/a3/jpis-53-110.PMC10133822.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9359123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of polydeoxyribonucleotide on early bone formation in lateral-window sinus floor elevation with simultaneous implant placement.","authors":"Dongseob Lee,&nbsp;Jungwon Lee,&nbsp;Ki-Tae Koo,&nbsp;Yang-Jo Seol,&nbsp;Yong-Moo Lee","doi":"10.5051/jpis.2202760138","DOIUrl":"https://doi.org/10.5051/jpis.2202760138","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to evaluate the impact of polydeoxyribonucleotide (PDRN) on histologic outcomes when implant placement and lateral sinus floor elevation are performed simultaneously.</p><p><strong>Methods: </strong>Three bimaxillary premolars (P2, P3, and P4) were extracted from 4 beagle dogs 2 months before lateral sinus floor elevation. After lateral elevation of the sinus membrane, each sinus was allocated to either the test or control group. Sinuses underwent either 1) collagenated synthetic bone graft with PDRN following lateral sinus floor elevation (test group) or 2) collagenated synthetic bone graft without PDRN after lateral sinus floor elevation (control group). Eight weeks after the surgical procedure, all animals were euthanised for a histologic and histomorphometric assessment. Augmented height (AH), protruding height (PH), and bone-to-implant contact in pristine (BIC_p) and augmented (BIC_a) bone were measured. The composition of the augmented area, which was divided into 3 areas of interest located in coronal, middle and apical areas (AOI_C, AOI_M, and AOI_A), was calculated with 3 parameters: the area percentage of new bone (pNB), residual bone graft particle (pRBP), and fibrovascular connective tissue (pFVT).</p><p><strong>Results: </strong>AH, PH, BIC_p, BIC_a total, BIC_a coronal, and BIC_a middle values were not significantly different between sinuses in the control and test groups (all <i>P</i>>0.05). The BIC_a apical of sinuses in the test group (76.7%±9.3%) showed statistically higher values than those of sinuses in the control group (55.6%±22.1%) (<i>P</i>=0.038). pNB, pRBP, and pFVT showed statistically significant differences between the 2 groups in AOI_A (<i>P</i>=0.038, <i>P=</i>0.028, and <i>P=</i>0.007, respectively). pNB, pRBP, and pFVT in AOI_C and AOI_M were not significantly different between samples in the control and test groups (all <i>P</i>>0.05).</p><p><strong>Conclusions: </strong>The histologic findings revealed that lateral sinus floor elevation with PDRN might improve early new bone formation and enable higher bone-to-implant contact.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 2","pages":"157-169"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/60/jpis-53-157.PMC10133820.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9728935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metformin enhances the osteogenic activity of rat bone marrow mesenchymal stem cells by inhibiting oxidative stress induced by diabetes mellitus: an <i>in vitro</i> and <i>in vivo</i> study.","authors":"Kai Dong,&nbsp;Wen-Juan Zhou,&nbsp;Zhong-Hao Liu","doi":"10.5051/jpis.2106240312","DOIUrl":"https://doi.org/10.5051/jpis.2106240312","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to determine whether metformin (MF) could alleviate the expresssion of reactive oxygen species (ROS) and improve the osteogenic ability of bone marrow mesenchymal stem cells derived from diabetic rats (drBMSCs) <i>in vitro</i>, and to evaluate the effect of MF on the ectopic osteogenesis of drBMSCs in a nude mouse model <i>in vivo</i>.</p><p><strong>Methods: </strong>BMSCs were extracted from normal and diabetic rats. <i>In vitro</i>, a cell viability assay (Cell Counting Kit-8), tests of alkaline phosphatase (ALP) activity, and western blot analysis were first used to determine the cell proliferation and osteogenic differentiation of drBMSCs that were subjected to treatment with different concentrations of MF (0, 50, 100, 200, 500 μM). The cells were then divided into 5 groups: (1) normal rat BMSCs (the BMSCs derived from normal rats group), (2) the drBMSCs group, (3) the drBMSCs + Mito-TEMPO (10 μM, ROS scavenger) group, (4) the drBMSCs + MF (200 μM) group, and (5) the drBMSCs + MF (200 μM) + H₂O₂ (50 μM, ROS activator) group. Intracellular ROS detection, a senescence-associated β-galactosidase assay, ALP staining, alizarin red staining, western blotting, and immunofluorescence assays were performed to determine the effects of MF on oxidative stress and osteogenic differentiation in drBMSCs. <i>In vivo</i>, the effect of MF on the ectopic osteogenesis of drBMSCs was evaluated in a nude mouse model.</p><p><strong>Results: </strong>MF effectively reduced ROS levels in drBMSCs. The cell proliferation, ALP activity, mineral deposition, and osteogenic-related protein expression of drBMSCs were demonstrably higher in the MF-treated group than in the non-MF-treated group. H₂O₂ inhibited the effects of MF. In addition, ectopic osteogenesis was significantly increased in drBMSCs treated with MF.</p><p><strong>Conclusions: </strong>MF promoted the proliferation and osteogenic differentiation of drBMSCs by inhibiting the oxidative stress induced by diabetes and enhenced the ectopic bone formation of drBMSCs in nude mice.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 1","pages":"54-68"},"PeriodicalIF":1.9,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/74/e2/jpis-53-54.PMC9943706.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10750476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Korean Academy of Periodontology's focus on national promotion projects for periodontal health.","authors":"Seung-Beom Kye","doi":"10.5051/jpis.235301edi01","DOIUrl":"https://doi.org/10.5051/jpis.235301edi01","url":null,"abstract":"","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 1","pages":"1"},"PeriodicalIF":1.9,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5d/fd/jpis-53-1.PMC9943707.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10753617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbial profiling of peri-implantitis compared to the periodontal microbiota in health and disease using 16S rRNA sequencing.","authors":"Hyun-Joo Kim,&nbsp;Dae-Hee Ahn,&nbsp;Yeuni Yu,&nbsp;Hyejung Han,&nbsp;Si Yeong Kim,&nbsp;Ji-Young Joo,&nbsp;Jin Chung,&nbsp;Hee Sam Na,&nbsp;Ju-Youn Lee","doi":"10.5051/jpis.2202080104","DOIUrl":"https://doi.org/10.5051/jpis.2202080104","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study was to analyze the microbial profile of individuals with peri-implantitis (PI) compared to those of periodontally healthy (PH) subjects and periodontitis (PT) subjects using Illumina sequencing.</p><p><strong>Methods: </strong>Buccal, supragingival, and subgingival plaque samples were collected from 109 subjects (PH: 30, PT: 49, and PI: 30). The V3-V4 region of 16S rRNA was sequenced and analyzed to profile the plaque microbiota.</p><p><strong>Results: </strong>Microbial community diversity in the PI group was higher than in the other groups, and the 3 groups showed significantly separated clusters in the buccal samples. The PI group showed different patterns of relative abundance from those in the PH and PT groups depending on the sampling site at both genus and phylum levels. In all samples, some bacterial species presented considerably higher relative abundances in the PI group than in the PH and PT groups, including <i>Anaerotignum lactatifermentans</i>, <i>Bacteroides vulgatus</i>, <i>Faecalibacterium prausnitzii</i>, <i>Olsenella uli</i>, <i>Parasutterella excrementihominis</i>, <i>Prevotella buccae</i>, <i>Pseudoramibacter alactolyticus</i>, <i>Treponema parvum</i>, and <i>Slackia exigua</i>. Network analysis identified that several well-known periodontal pathogens and newly recognized bacteria were closely correlated with each other.</p><p><strong>Conclusions: </strong>The composition of the microbiota was considerably different in PI subjects compared to PH and PT subjects, and these results could shed light on the mechanisms involved in the development of PI.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 1","pages":"69-84"},"PeriodicalIF":1.9,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/94/e6/jpis-53-69.PMC9943702.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10757791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}