Journal of Periodontal and Implant Science最新文献

{"title":"A retrospective epidemiological investigation of periodontitis risk and current smoking status based on the number of cigarettes per day and the Fagerström Test for Nicotine Dependence: a preliminary pilot study.","authors":"Ji-Hoo Han,&nbsp;Seong-Nyum Jeong,&nbsp;Jae-Hong Lee","doi":"10.5051/jpis.2202560128","DOIUrl":"https://doi.org/10.5051/jpis.2202560128","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to investigate the risk of periodontitis according to current smoking status based on the number of cigarettes smoked per day (CPD) and the Fagerström Test for Nicotine Dependence (FTND).</p><p><strong>Methods: </strong>All enrolled patients were diagnosed and classified according to the new periodontal classification scheme, and current smoking status was investigated via a self-reported questionnaire. The correlation between smoking status (CPD and FTND) and periodontitis risk (severity of periodontitis and tooth loss due to periodontal reasons) was statistically assessed using Spearman correlation coefficients. Moreover, partial correlation analyses between smoking and periodontal status were performed after adjusting for age, sex, and diabetes mellitus.</p><p><strong>Results: </strong>Overall, data from 74 men and 16 women (mean age: 48.1±10.8 years) were evaluated. The mean number of missing teeth, CPD, and FTND score were 3.5±5.2, 24.6±15.5, and 3.5±2, respectively. CPD and the FTND were significantly positively correlated with each other (<i>r</i>=0.741, <i>P</i><0.001). CPD and the FTND were also significantly correlated with the severity of periodontitis (CPD: <i>r</i>=0.457, <i>P</i><0.05 and FTND: <i>r</i>=0.326, <i>P</i><0.05) and the number of missing teeth due to periodontal reasons (CPD: <i>r</i>=0.525, <i>P</i><0.05 and FTND: <i>r</i>=0.480, <i>P</i><0.05), respectively.</p><p><strong>Conclusions: </strong>Within the limitations of this study, both CPD and the FTND were significantly correlated with the severity of periodontitis and the number of periodontally compromised extracted teeth.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 2","pages":"135-144"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2b/77/jpis-53-135.PMC10133818.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9728934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>In vitro</i> investigation of the antibacterial and anti-inflammatory effects of LED irradiation.","authors":"Jungwon Lee,&nbsp;Hyun-Yong Song,&nbsp;Sun-Hee Ahn,&nbsp;Woosub Song,&nbsp;Yang-Jo Seol,&nbsp;Yong-Moo Lee,&nbsp;Ki-Tae Koo","doi":"10.5051/jpis.2200920046","DOIUrl":"https://doi.org/10.5051/jpis.2200920046","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the proper wavelengths for safe levels of light-emitting diode (LED) irradiation with bactericidal and photobiomodulation effects <i>in vitro</i>.</p><p><strong>Methods: </strong>Cell viability tests of fibroblasts and osteoblasts after LED irradiation at 470, 525, 590, 630, and 850 nm were performed using the thiazolyl blue tetrazolium bromide assay. The bactericidal effect of 470-nm LED irradiation was analyzed with <i>Streptococcus gordonii</i>, <i>Aggregatibacter actinomycetemcomitans</i>, <i>Fusobacterium nucleatum</i>, <i>Porphyromonas gingivalis</i>, and <i>Tannerella forsythia</i>. Levels of nitric oxide, a proinflammatory mediator, were measured to identify the anti-inflammatory effect of LED irradiation on lipopolysaccharide-stimulated inflammation in RAW 264.7 macrophages.</p><p><strong>Results: </strong>LED irradiation at wavelengths of 470, 525, 590, 630, and 850 nm showed no cytotoxic effect on fibroblasts and osteoblasts. LED irradiation at 630 and 850 nm led to fibroblast proliferation compared to no LED irradiation. LED irradiation at 470 nm resulted in bactericidal effects on <i>S. gordonii</i>, <i>A. actinomycetemcomitans</i>, <i>F. nucleatum</i>, <i>P. gingivalis</i>, and <i>T. forsythia.</i> Lipopolysaccharide (LPS)-induced RAW 264.7 inflammation was reduced by irradiation with 525-nm LED before LPS treatment and irradiation with 630-nm LED after LPS treatment; however, the effects were limited.</p><p><strong>Conclusions: </strong>LED irradiation at 470 nm showed bactericidal effects, while LED irradiation at 525 and 630 nm showed preventive and treatment effects on LPS-induced RAW 264.7 inflammation. The application of LED irradiation has potential as an adjuvant in periodontal therapy, although further investigations should be performed <i>in vivo</i>.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 2","pages":"110-119"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/57/a3/jpis-53-110.PMC10133822.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9359123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of polydeoxyribonucleotide on early bone formation in lateral-window sinus floor elevation with simultaneous implant placement.","authors":"Dongseob Lee,&nbsp;Jungwon Lee,&nbsp;Ki-Tae Koo,&nbsp;Yang-Jo Seol,&nbsp;Yong-Moo Lee","doi":"10.5051/jpis.2202760138","DOIUrl":"https://doi.org/10.5051/jpis.2202760138","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to evaluate the impact of polydeoxyribonucleotide (PDRN) on histologic outcomes when implant placement and lateral sinus floor elevation are performed simultaneously.</p><p><strong>Methods: </strong>Three bimaxillary premolars (P2, P3, and P4) were extracted from 4 beagle dogs 2 months before lateral sinus floor elevation. After lateral elevation of the sinus membrane, each sinus was allocated to either the test or control group. Sinuses underwent either 1) collagenated synthetic bone graft with PDRN following lateral sinus floor elevation (test group) or 2) collagenated synthetic bone graft without PDRN after lateral sinus floor elevation (control group). Eight weeks after the surgical procedure, all animals were euthanised for a histologic and histomorphometric assessment. Augmented height (AH), protruding height (PH), and bone-to-implant contact in pristine (BIC_p) and augmented (BIC_a) bone were measured. The composition of the augmented area, which was divided into 3 areas of interest located in coronal, middle and apical areas (AOI_C, AOI_M, and AOI_A), was calculated with 3 parameters: the area percentage of new bone (pNB), residual bone graft particle (pRBP), and fibrovascular connective tissue (pFVT).</p><p><strong>Results: </strong>AH, PH, BIC_p, BIC_a total, BIC_a coronal, and BIC_a middle values were not significantly different between sinuses in the control and test groups (all <i>P</i>>0.05). The BIC_a apical of sinuses in the test group (76.7%±9.3%) showed statistically higher values than those of sinuses in the control group (55.6%±22.1%) (<i>P</i>=0.038). pNB, pRBP, and pFVT showed statistically significant differences between the 2 groups in AOI_A (<i>P</i>=0.038, <i>P=</i>0.028, and <i>P=</i>0.007, respectively). pNB, pRBP, and pFVT in AOI_C and AOI_M were not significantly different between samples in the control and test groups (all <i>P</i>>0.05).</p><p><strong>Conclusions: </strong>The histologic findings revealed that lateral sinus floor elevation with PDRN might improve early new bone formation and enable higher bone-to-implant contact.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 2","pages":"157-169"},"PeriodicalIF":1.9,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/60/jpis-53-157.PMC10133820.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9728935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metformin enhances the osteogenic activity of rat bone marrow mesenchymal stem cells by inhibiting oxidative stress induced by diabetes mellitus: an <i>in vitro</i> and <i>in vivo</i> study.","authors":"Kai Dong,&nbsp;Wen-Juan Zhou,&nbsp;Zhong-Hao Liu","doi":"10.5051/jpis.2106240312","DOIUrl":"https://doi.org/10.5051/jpis.2106240312","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to determine whether metformin (MF) could alleviate the expresssion of reactive oxygen species (ROS) and improve the osteogenic ability of bone marrow mesenchymal stem cells derived from diabetic rats (drBMSCs) <i>in vitro</i>, and to evaluate the effect of MF on the ectopic osteogenesis of drBMSCs in a nude mouse model <i>in vivo</i>.</p><p><strong>Methods: </strong>BMSCs were extracted from normal and diabetic rats. <i>In vitro</i>, a cell viability assay (Cell Counting Kit-8), tests of alkaline phosphatase (ALP) activity, and western blot analysis were first used to determine the cell proliferation and osteogenic differentiation of drBMSCs that were subjected to treatment with different concentrations of MF (0, 50, 100, 200, 500 μM). The cells were then divided into 5 groups: (1) normal rat BMSCs (the BMSCs derived from normal rats group), (2) the drBMSCs group, (3) the drBMSCs + Mito-TEMPO (10 μM, ROS scavenger) group, (4) the drBMSCs + MF (200 μM) group, and (5) the drBMSCs + MF (200 μM) + H₂O₂ (50 μM, ROS activator) group. Intracellular ROS detection, a senescence-associated β-galactosidase assay, ALP staining, alizarin red staining, western blotting, and immunofluorescence assays were performed to determine the effects of MF on oxidative stress and osteogenic differentiation in drBMSCs. <i>In vivo</i>, the effect of MF on the ectopic osteogenesis of drBMSCs was evaluated in a nude mouse model.</p><p><strong>Results: </strong>MF effectively reduced ROS levels in drBMSCs. The cell proliferation, ALP activity, mineral deposition, and osteogenic-related protein expression of drBMSCs were demonstrably higher in the MF-treated group than in the non-MF-treated group. H₂O₂ inhibited the effects of MF. In addition, ectopic osteogenesis was significantly increased in drBMSCs treated with MF.</p><p><strong>Conclusions: </strong>MF promoted the proliferation and osteogenic differentiation of drBMSCs by inhibiting the oxidative stress induced by diabetes and enhenced the ectopic bone formation of drBMSCs in nude mice.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 1","pages":"54-68"},"PeriodicalIF":1.9,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/74/e2/jpis-53-54.PMC9943706.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10750476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Korean Academy of Periodontology's focus on national promotion projects for periodontal health.","authors":"Seung-Beom Kye","doi":"10.5051/jpis.235301edi01","DOIUrl":"https://doi.org/10.5051/jpis.235301edi01","url":null,"abstract":"","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 1","pages":"1"},"PeriodicalIF":1.9,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5d/fd/jpis-53-1.PMC9943707.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10753617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbial profiling of peri-implantitis compared to the periodontal microbiota in health and disease using 16S rRNA sequencing.","authors":"Hyun-Joo Kim,&nbsp;Dae-Hee Ahn,&nbsp;Yeuni Yu,&nbsp;Hyejung Han,&nbsp;Si Yeong Kim,&nbsp;Ji-Young Joo,&nbsp;Jin Chung,&nbsp;Hee Sam Na,&nbsp;Ju-Youn Lee","doi":"10.5051/jpis.2202080104","DOIUrl":"https://doi.org/10.5051/jpis.2202080104","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study was to analyze the microbial profile of individuals with peri-implantitis (PI) compared to those of periodontally healthy (PH) subjects and periodontitis (PT) subjects using Illumina sequencing.</p><p><strong>Methods: </strong>Buccal, supragingival, and subgingival plaque samples were collected from 109 subjects (PH: 30, PT: 49, and PI: 30). The V3-V4 region of 16S rRNA was sequenced and analyzed to profile the plaque microbiota.</p><p><strong>Results: </strong>Microbial community diversity in the PI group was higher than in the other groups, and the 3 groups showed significantly separated clusters in the buccal samples. The PI group showed different patterns of relative abundance from those in the PH and PT groups depending on the sampling site at both genus and phylum levels. In all samples, some bacterial species presented considerably higher relative abundances in the PI group than in the PH and PT groups, including <i>Anaerotignum lactatifermentans</i>, <i>Bacteroides vulgatus</i>, <i>Faecalibacterium prausnitzii</i>, <i>Olsenella uli</i>, <i>Parasutterella excrementihominis</i>, <i>Prevotella buccae</i>, <i>Pseudoramibacter alactolyticus</i>, <i>Treponema parvum</i>, and <i>Slackia exigua</i>. Network analysis identified that several well-known periodontal pathogens and newly recognized bacteria were closely correlated with each other.</p><p><strong>Conclusions: </strong>The composition of the microbiota was considerably different in PI subjects compared to PH and PT subjects, and these results could shed light on the mechanisms involved in the development of PI.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 1","pages":"69-84"},"PeriodicalIF":1.9,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/94/e6/jpis-53-69.PMC9943702.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10757791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sequential anti-inflammatory and osteogenic effects of a dual drug delivery scaffold loaded with parthenolide and naringin in periodontitis.","authors":"Rui Chen,&nbsp;Mengting Wang,&nbsp;Qiaoling Qi,&nbsp;Yanli Tang,&nbsp;Zhenzhao Guo,&nbsp;Shuai Wu,&nbsp;Qiyan Li","doi":"10.5051/jpis.2105700285","DOIUrl":"https://doi.org/10.5051/jpis.2105700285","url":null,"abstract":"<p><strong>Purpose: </strong>Our pilot study showed that a 3-dimensional dual drug delivery scaffold (DDDS) loaded with Chinese herbs significantly increased the regenerated bone volume fraction. This study aimed to confirm the synergistic anti-inflammatory and osteogenic preclinical effects of this system.</p><p><strong>Methods: </strong>The targets and pathways of parthenolide and naringin were predicted. Three cell models were used to assess the anti-inflammatory effects of parthenolide and the osteogenic effects of naringin. First, the distance between the cementoenamel junction and alveolar bone crest (CEJ-ABC) and the bone mineral density (BMD) of surgical defects were measured in a rat model of periodontitis with periodontal fenestration defects. Additionally, the mRNA expression levels of matrix metallopeptidase 9 (MMP9) and alkaline phosphatase (ALP) were measured. Furthermore, the number of inflammatory cells and osteoclasts, as well as the protein expression levels of tumor necrosis factor-alpha (TNF-α) and levels of ALP were determined.</p><p><strong>Results: </strong>Target prediction suggested prostaglandin peroxidase synthase (PTGS2) as a potential target of parthenolide, while cytochrome P450 family 19 subfamily A1 (CYP19A1) and taste 2 receptor member 31 (TAS2R31) were potential targets of naringin. Parthenolide mainly targeted inflammation-related pathways, while naringin participated in steroid hormone synthesis and taste transduction. <i>In vitro</i> experiments revealed significant anti-inflammatory effects of parthenolide on RAW264.7 cells, and significant osteogenic effects of naringin on bone marrow mesenchymal stem cells and MC3T3-E1 cells. DDDS loaded with parthenolide and naringin decreased the CEJ-ABC distance and increased BMD and ALP levels in a time-dependent manner. Inflammation was significantly alleviated after 14 days of DDDS treatment. Additionally, after 56 days, the DDDS group exhibited the highest BMD and ALP levels.</p><p><strong>Conclusions: </strong>DDDS loaded with parthenolide and naringin in a rat model achieved significant synergistic anti-inflammatory and osteogenic effects, providing powerful preclinical evidence.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 1","pages":"20-37"},"PeriodicalIF":1.9,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/01/c5/jpis-53-20.PMC9943701.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10757788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of the stage and grade of periodontitis according to the current classification of periodontal and peri-implant diseases and conditions (2018) using machine learning algorithms.","authors":"Kübra Ertaş, Ihsan Pence, Melike Siseci Cesmeli, Zuhal Yetkin Ay","doi":"10.5051/jpis.2201060053","DOIUrl":"10.5051/jpis.2201060053","url":null,"abstract":"<p><strong>Purpose: </strong>The current Classification of Periodontal and Peri-Implant Diseases and Conditions, published and disseminated in 2018, involves some difficulties and causes diagnostic conflicts due to its criteria, especially for inexperienced clinicians. The aim of this study was to design a decision system based on machine learning algorithms by using clinical measurements and radiographic images in order to determine and facilitate the staging and grading of periodontitis.</p><p><strong>Methods: </strong>In the first part of this study, machine learning models were created using the Python programming language based on clinical data from 144 individuals who presented to the Department of Periodontology, Faculty of Dentistry, Süleyman Demirel University. In the second part, panoramic radiographic images were processed and classification was carried out with deep learning algorithms.</p><p><strong>Results: </strong>Using clinical data, the accuracy of staging with the tree algorithm reached 97.2%, while the random forest and k-nearest neighbor algorithms reached 98.6% accuracy. The best staging accuracy for processing panoramic radiographic images was provided by a hybrid network model algorithm combining the proposed ResNet50 architecture and the support vector machine algorithm. For this, the images were preprocessed, and high success was obtained, with a classification accuracy of 88.2% for staging. However, in general, it was observed that the radiographic images provided a low level of success, in terms of accuracy, for modeling the grading of periodontitis.</p><p><strong>Conclusions: </strong>The machine learning-based decision system presented herein can facilitate periodontal diagnoses despite its current limitations. Further studies are planned to optimize the algorithm and improve the results.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 1","pages":"38-53"},"PeriodicalIF":2.2,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4f/1d/jpis-53-38.PMC9943704.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10750477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of a simplified drilling protocol at 50 rpm on heat generation under water-free conditions: an <i>in vitro</i> study.","authors":"Hyeon-Ji Jang,&nbsp;Jin-Un Yoon,&nbsp;Ji-Young Joo,&nbsp;Ju-Youn Lee,&nbsp;Hyun-Joo Kim","doi":"10.5051/jpis.2201400070","DOIUrl":"https://doi.org/10.5051/jpis.2201400070","url":null,"abstract":"<p><strong>Purpose: </strong>In recent years, guided implant surgery has been widely used for the convenience of patients and surgeons. Further streamlining the surgical procedure would make implant surgery more convenient. Low-speed water-free conditions are often used in guided implant surgery. Therefore, in this study, we attempted to confirm once again whether drilling was safe at a low speed without water. The main purpose of this study was to evaluate whether a simplified drilling protocol that omits some intermediate steps in the drilling process was safe from the viewpoint of heat generation.</p><p><strong>Methods: </strong>D1 density artificial bone blocks were drilled under 50 rpm, 10 N·cm water-free conditions, and the surface temperature was measured using a digital infrared camera. First, drilling was performed with the sequential drilling method, which is the most widely used technique. Second, for each drill diameter, the temperature change was measured while performing simplified drilling with omission of the previous 1, 2, or 3 steps.</p><p><strong>Results: </strong>In sequential drilling, the heat generated during drilling at all diameters was less than the critical temperature of osteonecrosis (47°C) except for the ⌀2 drill. Statistical significance was observed in all groups when comparing sequential and simplified drilling in the ⌀3.2, ⌀3.8, and ⌀4.3 drills (<i>P</i><0.001). However, in the simplified drilling procedures, the temperature was below the osteonecrosis threshold temperature (47°C) except for the ⌀4.3 drill with the omission of the previous 3 steps (⌀3.0, ⌀3.2, and ⌀3.8).</p><p><strong>Conclusions: </strong>In general, drilling under low-speed, water-free conditions has shown stable results in terms of heat generation. Simplified drilling showed statistically significantly greater heat generation than sequential drilling. However, most of the diameters and omitted steps seem to be clinically acceptable, so it will be useful if an appropriate selection is made according to the patient's clinical condition.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 1","pages":"85-95"},"PeriodicalIF":1.9,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/05/d7/jpis-53-85.PMC9943703.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10757787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do platelet concentrates accelerate orthodontic tooth movement?: a systematic review.","authors":"Sergio Herrero-Llorente,&nbsp;Angel-Orión Salgado-Peralvo,&nbsp;Jan G J H Schols","doi":"10.5051/jpis.2201600080","DOIUrl":"https://doi.org/10.5051/jpis.2201600080","url":null,"abstract":"<p><strong>Purpose: </strong>Surgical techniques in orthodontics have received widespread attention in recent years. Meanwhile, biomaterials with high molecular content have been introduced, such as platelet concentrates (PCs), which may accelerate orthodontic tooth movement (OTM) and reduce periodontal damage. The present systematic review aimed to answer the following PICO question: \"In patients in whom orthodontic surgical techniques are performed (P), what is the effectiveness of using PCs over the surgical site (I) when compared to not placing PCs (C) to achieve faster tooth movement (O)?\"</p><p><strong>Methods: </strong>A search was performed in 6 databases. The criteria employed were those described in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses declaration. The present review included studies with a control group that provided information about the influence of PCs on the rate of OTM.</p><p><strong>Results: </strong>The electronic search identified 10 studies that met the established criteria.</p><p><strong>Conclusions: </strong>The included studies were very diverse, making it difficult to draw convincing conclusions. However, a tendency was observed for OTM to be accelerated when PCs were used as an adjuvant for canine distalization after premolar extraction when distalization was started in the same session. Likewise, studies seem to indicate an association between PC injection and the amount of canine retraction. However, it is not possible to affirm that the use of PCs in corticotomy shortens the overall treatment time, as this question has not been studied adequately.</p><p><strong>Trial registration: </strong>PROSPERO Identifier: CRD42021278542.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 1","pages":"2-19"},"PeriodicalIF":1.9,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/70/b3/jpis-53-2.PMC9943705.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10757790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}