Journal of Periodontal and Implant Science最新文献

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Evaluation of the effectiveness of diode laser therapy in conjunction with nonsurgical treatment of peri-implantitis. 二极管激光联合非手术治疗种植体周围炎的疗效评价。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-10-01 Epub Date: 2023-02-03 DOI: 10.5051/jpis.2203140157
Dicle Altindal, Eylem Ayhan Alkan, Metin Calisir
{"title":"Evaluation of the effectiveness of diode laser therapy in conjunction with nonsurgical treatment of peri-implantitis.","authors":"Dicle Altindal,&nbsp;Eylem Ayhan Alkan,&nbsp;Metin Calisir","doi":"10.5051/jpis.2203140157","DOIUrl":"10.5051/jpis.2203140157","url":null,"abstract":"<p><strong>Purpose: </strong>Peri-implantitis (PI) is an inflammatory condition associated with the destruction of bone tissue around a dental implant, and diode lasers can be used to treat this disease. In this study, we aimed to evaluate the effectiveness of a 940-nm diode laser for the nonsurgical treatment of PI.</p><p><strong>Methods: </strong>Twenty patients (8 women and 12 men) were enrolled in a split-mouth randomized controlled study. In the control group (CG), mechanical debridement with titanium curettes accompanied by airflow was performed around the implants. The test group (TG) was treated similarly, but with the use of a diode laser. Clinical measurements (plaque index, gingival index [GI], probing pocket depth [PPD], bleeding on probing [BOP], clinical attachment level, and interleukin-1β [IL-1β] in the peri-implant crevicular fluid) were evaluated and recorded at baseline and 3 months. IL-1β levels were determined using the enzyme-linked immunosorbent assay method.</p><p><strong>Results: </strong>The symptoms were alleviated in both groups at 3 months as assessed through clinical measurements. GI, BOP, and PPD were significantly lower in the TG than in the CG (<i>P</i><0.05). The IL-1β level increased post-treatment in both groups, but this increase was only statistically significant (<i>P</i><0.05) in the CG.</p><p><strong>Conclusions: </strong>The diode laser enabled improvements in clinical parameters in the peri-implant tissue. However, it did not reduce IL-1β levels after treatment. Further studies about the use of diode lasers in the treatment of PI will be necessary to evaluate the effects of diode lasers in PI treatment.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":" ","pages":"376-387"},"PeriodicalIF":1.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627738/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9628492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in the components of salivary exosomes due to initial periodontal therapy. 最初牙周治疗引起的唾液外泌体成分的变化。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-10-01 Epub Date: 2023-01-26 DOI: 10.5051/jpis.2203700185
Arisa Yamaguchi, Yuto Tsuruya, Kazuma Igarashi, Zhenyu Jin, Mizuho Yamazaki-Takai, Hideki Takai, Yohei Nakayama, Yorimasa Ogata
{"title":"Changes in the components of salivary exosomes due to initial periodontal therapy.","authors":"Arisa Yamaguchi,&nbsp;Yuto Tsuruya,&nbsp;Kazuma Igarashi,&nbsp;Zhenyu Jin,&nbsp;Mizuho Yamazaki-Takai,&nbsp;Hideki Takai,&nbsp;Yohei Nakayama,&nbsp;Yorimasa Ogata","doi":"10.5051/jpis.2203700185","DOIUrl":"10.5051/jpis.2203700185","url":null,"abstract":"<p><strong>Purpose: </strong>Exosomes are membrane vesicles that are present in body fluids and contain proteins, lipids, and microRNA (miRNA). Periodontal tissue examinations assess the degree of periodontal tissue destruction according to the probing depth (PD), clinical attachment loss (CAL), bleeding on probing, and X-ray examinations. However, the accurate evaluation of the prognosis of periodontitis is limited. In this study, we collected saliva from patients before and after initial periodontal therapy (IPT) and compared changes in the clinical parameters of periodontitis with changes in the components of salivary exosomes.</p><p><strong>Methods: </strong>Saliva was collected from patients with stage III and IV periodontitis at the first visit and post-IPT. Exosomes were purified from the saliva, and total protein and RNA were extracted. Changes in expression levels of C6, CD81, TSG101, HSP70, and 6 kinds of miRNA were analyzed by western blots and real-time polymerase chain reaction.</p><p><strong>Results: </strong>Patients with increased C6 expression after IPT had significantly higher levels of periodontal inflamed surface area (PISA), miR-142, and miR-144 before and after IPT than patients with decreased C6 expression after IPT. Patients with decreased and unchanged CD81 expression after IPT showed significantly higher PD, CAL, and PISA before IPT than after IPT. Patients with decreased and unchanged TSG101 expression after IPT had significantly higher PD before IPT than after IPT. Patients with increased HSP70 expression after IPT had significantly higher PD and PISA before and after IPT than patients with unchanged HSP70 after IPT. The expression levels of miR-142, miR-144, miR-200b, and miR-223 changed with changes in the levels of C6, CD81, TSG101, and HSP70 in the salivary exosomes of periodontitis patients before and after IPT.</p><p><strong>Conclusions: </strong>The expression levels of proteins and miRNAs in salivary exosomes significantly changed after IPT in periodontitis patients, suggesting that the components of exosomes could serve as biomarkers for periodontitis.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":" ","pages":"347-361"},"PeriodicalIF":1.9,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9482134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanotechnology and periodontics. 纳米技术和牙周病。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-08-01 DOI: 10.5051/jpis.235304edi01
Deepith Kelotte, Anil Melath, Subair Kaykool, Nanditha Chandran
{"title":"Nanotechnology and periodontics.","authors":"Deepith Kelotte,&nbsp;Anil Melath,&nbsp;Subair Kaykool,&nbsp;Nanditha Chandran","doi":"10.5051/jpis.235304edi01","DOIUrl":"https://doi.org/10.5051/jpis.235304edi01","url":null,"abstract":"The periodontium undergoes morphological and functional variations, as well as changes associated with age. Traditional treatments such as scaling, root planing, and periodontal flap surgery have been shown to be effective. The treatment of progressive periodontal diseases has been proven beneficial when combined with adequate post-operative supportive periodontal care [1]. Specialised nanoparticles, with particle sizes measured in nanometres, can be engineered to target oral tissues, including the periodontium. Nano-scale biosensors can be used to diagnose periodontal disorders. These sensors are capable of identifying substances found in bodily fluids such as saliva, blood, and gingival crevicular fluid [2]. These nanotechnologies are also employed for administering medication, injecting local anaesthesia, and for diagnostic purposes. Dentists can control nanorobots using onboard computers, transmitting signals for specific treatment techniques. Dentifrobots are devices that reside sub-occlusally and are administered via mouth rinse or toothpaste [3]. These dentifrobots can inspect supragingival and subgingival areas at least once a day, aiding in the ongoing removal of calculus and converting trapped organic molecules into harmless, odourless vapours [4]. Nanorobots will have the ability to distinguish between different types of cells by analysing their surface antigens. This is achieved by using chemotactic sensors that are tuned to specific antigens on target cells. Once the nanorobots have completed their task, they can be removed through the human excretory system or by active scavenger systems [4]. Nanoparticles offer numerous advantages in the delivery of bioactive chemicals and drugs.","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 4","pages":"245-247"},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ba/fd/jpis-53-245.PMC10465811.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10500310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Temporal changes of periodontal tissue pathology in a periodontitis animal model. 牙周炎动物模型牙周组织病理学的时间变化。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-08-01 DOI: 10.5051/jpis.2203420171
Hyunpil Yoon, Bo Hyun Jung, Ki-Yeon Yoo, Jong-Bin Lee, Heung-Sik Um, Beom-Seok Chang, Jae-Kwan Lee
{"title":"Temporal changes of periodontal tissue pathology in a periodontitis animal model.","authors":"Hyunpil Yoon,&nbsp;Bo Hyun Jung,&nbsp;Ki-Yeon Yoo,&nbsp;Jong-Bin Lee,&nbsp;Heung-Sik Um,&nbsp;Beom-Seok Chang,&nbsp;Jae-Kwan Lee","doi":"10.5051/jpis.2203420171","DOIUrl":"https://doi.org/10.5051/jpis.2203420171","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to characterize the early stages of periodontal disease and determine the optimal period for its evaluation in a mouse model. The association between the duration of ligation and its effect on the dentogingival area in mice was evaluated using micro-computed tomography (CT) and histological analysis.</p><p><strong>Methods: </strong>Ninety mice were allocated to an untreated control group or a ligation group in which periodontitis was induced by a 6-0 silk ligation around the left second maxillary molar. Mice were sacrificed at 1, 2, 3, 4, 5, 8, 11, and 14 days after ligature placement. Alveolar bone destruction was evaluated using micro-CT. Histological analysis was performed to assess the immune-inflammatory processes in the periodontal tissue.</p><p><strong>Results: </strong>No significant difference in alveolar bone loss was found compared to the control group until day 3 after ligature placement, and a gradual increase in alveolar bone loss was observed from 4 to 8 days following ligature placement. No significant between-group differences were observed after 8 days. The histological analysis demonstrated that the inflammatory response was evident from day 4.</p><p><strong>Conclusions: </strong>Our findings in a mouse model provide experimental evidence that ligature-induced periodontitis models offer a consistent progression of disease with marginal attachment down-growth, inflammatory infiltration, and alveolar bone loss.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 4","pages":"248-258"},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5a/f9/jpis-53-248.PMC10465809.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10124559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Evaluation of the clinical and radiographic effectiveness of treating peri-implant bone defects with a new biphasic calcium phosphate bone graft: a prospective, multicenter randomized controlled trial. 新型双相磷酸钙骨移植物治疗种植体周围骨缺损的临床和放射学疗效评估:一项前瞻性、多中心随机对照试验。
IF 2.2 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-08-01 Epub Date: 2023-06-09 DOI: 10.5051/jpis.2300640032
Jae-Hong Lee, Hyun-Wook An, Jae-Seung Im, Woo-Joo Kim, Dong-Won Lee, Jeong-Ho Yun
{"title":"Evaluation of the clinical and radiographic effectiveness of treating peri-implant bone defects with a new biphasic calcium phosphate bone graft: a prospective, multicenter randomized controlled trial.","authors":"Jae-Hong Lee, Hyun-Wook An, Jae-Seung Im, Woo-Joo Kim, Dong-Won Lee, Jeong-Ho Yun","doi":"10.5051/jpis.2300640032","DOIUrl":"10.5051/jpis.2300640032","url":null,"abstract":"<p><strong>Purpose: </strong>Biphasic calcium phosphate (BCP), a widely used biomaterial for bone regeneration, contains synthetic hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP), the ratio of which can be adjusted to modulate the rate of degradation. The aim of this study was to evaluate the clinical and radiographic benefits of reconstructing peri-implant bone defects with a newly developed BCP consisting of 40% β-TCP and 60% HA compared to demineralized bovine bone mineral (DBBM).</p><p><strong>Methods: </strong>This prospective, multicenter, parallel, single-blind randomized controlled trial was conducted at the periodontology departments of 3 different dental hospitals. Changes in clinical (defect width and height) and radiographic (augmented horizontal bone thickness) parameters were measured between implant surgery with guided bone regeneration (GBR) and re-entry surgery. Postoperative discomfort (severity and duration of pain and swelling) and early soft-tissue wound healing (dehiscence and inflammation) were also assessed. Data were compared between the BCP (test) and DBBM (control) groups using the independent <i>t</i>-test and the χ² test.</p><p><strong>Results: </strong>Of the 53 cases included, 27 were in the test group and 26 were in the control group. After a healing period of 18 weeks, the full and mean resolution of buccal dehiscence defects were 59.3% (n=16) and 71.3% in the test group and 42.3% (n=11) and 57.9% in the control group, respectively. There were no significant differences between the groups in terms of the change in mean horizontal bone augmentation (test group: -0.50±0.66 mm vs. control groups: -0.66±0.83 mm, <i>P</i>=0.133), postoperative discomfort, or early wound healing. No adverse or fatal complications occurred in either group.</p><p><strong>Conclusion: </strong>The GBR procedure with the newly developed BCP showed favorable clinical, radiographic, postoperative discomfort-related, and early wound healing outcomes for peri-implant dehiscence defects that were similar to those for DBBM.</p><p><strong>Trial registration: </strong>Clinical Research Information Service Identifier: KCT0006428.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 4","pages":"306-317"},"PeriodicalIF":2.2,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bf/56/jpis-53-306.PMC10465810.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10128795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The efficacy of different implant surface decontamination methods using spectrophotometric analysis: an in vitro study. 用分光光度法分析不同种植体表面去污方法的效果:体外研究。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-08-01 DOI: 10.5051/jpis.2203500175
Roberto Giffi, Davide Pietropaoli, Leonardo Mancini, Francesco Tarallo, Philipp Sahrmann, Enrico Marchetti
{"title":"The efficacy of different implant surface decontamination methods using spectrophotometric analysis: an <i>in vitro</i> study.","authors":"Roberto Giffi,&nbsp;Davide Pietropaoli,&nbsp;Leonardo Mancini,&nbsp;Francesco Tarallo,&nbsp;Philipp Sahrmann,&nbsp;Enrico Marchetti","doi":"10.5051/jpis.2203500175","DOIUrl":"https://doi.org/10.5051/jpis.2203500175","url":null,"abstract":"<p><strong>Purpose: </strong>Various methods have been proposed to achieve the nearly complete decontamination of the surface of implants affected by peri-implantitis. We investigated the <i>in vitro</i> debridement efficiency of multiple decontamination methods (Gracey curettes [GC], glycine air-polishing [G-Air], erythritol air-polishing [E-Air] and titanium brushes [TiB]) using a novel spectrophotometric ink-model in 3 different bone defect settings (30°, 60°, and 90°).</p><p><strong>Methods: </strong>Forty-five dental implants were stained with indelible ink and mounted in resin models, which simulated standardised peri-implantitis defects with different bone defect angulations (30°, 60°, and 90°). After each run of instrumentation, the implants were removed from the resin model, and the ink was dissolved in ethanol (97%). A spectrophotometric analysis was performed to detect colour remnants in order to measure the cumulative uncleaned surface area of the implants. Scanning electron microscopy images were taken to assess micromorphological surface changes.</p><p><strong>Results: </strong>Generally, the 60° bone defects were the easiest to debride, and the 30° defects were the most difficult (ink absorption peak: 0.26±0.04 for 60° defects; 0.32±0.06 for 30° defects; 0.27±0.04 for 90° defects). The most effective debridement method was TiB, independently of the bone defect type (TiB vs. GC: <i>P</i><0.0001; TiB vs. G-Air: <i>P</i>=0.0017; TiB vs. GE-Air: <i>P=</i>0.0007). GE-Air appeared to be the least efficient method for biofilm debridement.</p><p><strong>Conclusions: </strong>T-brushes seem to be a promising decontamination method compared to the other techniques, whereas G-Air was less aggressive on the implant surface. The use of a spectrophotometric model was shown to be a novel but promising assessment method for <i>in vitro</i> ink studies.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 4","pages":"295-305"},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5c/28/jpis-53-295.PMC10465813.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10126686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Increased prevalence of periodontitis with hypouricemic status: findings from the Korean National Health and Nutrition Examination Survey, 2016-2018. 牙周炎伴低尿酸血症的患病率增加:2016-2018年韩国国家健康与营养检查调查结果
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-08-01 DOI: 10.5051/jpis.2202220111
Ji-Young Joo, Hae Ryoun Park, Youngseuk Cho, Yunhwan Noh, Chang Hun Lee, Seung-Geun Lee
{"title":"Increased prevalence of periodontitis with hypouricemic status: findings from the Korean National Health and Nutrition Examination Survey, 2016-2018.","authors":"Ji-Young Joo,&nbsp;Hae Ryoun Park,&nbsp;Youngseuk Cho,&nbsp;Yunhwan Noh,&nbsp;Chang Hun Lee,&nbsp;Seung-Geun Lee","doi":"10.5051/jpis.2202220111","DOIUrl":"https://doi.org/10.5051/jpis.2202220111","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to investigate the relationship between serum uric acid (SUA) levels and the risk of periodontitis in Korean adults using data from the Korean National Health and Nutrition Examination Survey (KNHANES).</p><p><strong>Methods: </strong>This cross-sectional study used data from the KNHANES 2016-2018 and analysed 12,735 Korean adults aged ≥19 years who underwent oral examinations. Hypouricemia was defined as SUA <3 mg/dL in men and <2 mg/dL in women, and hyperuricemia was defined as SUA ≥7 mg/dL in men and ≥6 mg/dL in women.</p><p><strong>Results: </strong>The weighted prevalence of hypouricemia and hyperuricemia was 0.6% and 12.9%, respectively. The overall weighted periodontitis rate was 30.5%. The frequency of periodontitis in subjects with hypouricemia, normouricemia, and hyperuricemia were 51.1%, 30.3%, and 30.6%, respectively. Study participants with hypouricemia were significantly older, had significantly fasting blood glucose levels, and had better kidney function than non-hypouricemic participants. In univariate logistic regression analyses, hypouricemia was associated with periodontitis, but hyperuricemia was not. The fully adjusted model revealed that the adjusted odds ratio of hypouricemia for periodontitis was 1.62 (95% confidence interval, 1.13-2.33), while the relationship between hyperuricemia and periodontitis in the multivariable logistic regression model was not significant.</p><p><strong>Conclusions: </strong>The results of this study suggest that hypouricemia is associated with an increased risk of periodontitis.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 4","pages":"283-294"},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ec/64/jpis-53-283.PMC10465814.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10126687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The optimal dosage of hyaluronic acid for bone regeneration in rat calvarial defects. 透明质酸用于大鼠颅骨缺损骨再生的最佳剂量。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-08-01 DOI: 10.5051/jpis.2203000150
Ling Li, Jungwon Lee, Young-Dan Cho, Sungtae Kim, Yang-Jo Seol, Yong-Moo Lee, Ki-Tae Koo
{"title":"The optimal dosage of hyaluronic acid for bone regeneration in rat calvarial defects.","authors":"Ling Li,&nbsp;Jungwon Lee,&nbsp;Young-Dan Cho,&nbsp;Sungtae Kim,&nbsp;Yang-Jo Seol,&nbsp;Yong-Moo Lee,&nbsp;Ki-Tae Koo","doi":"10.5051/jpis.2203000150","DOIUrl":"https://doi.org/10.5051/jpis.2203000150","url":null,"abstract":"<p><strong>Purpose: </strong>Hyaluronic acid (HA) affects angiogenesis and promotes the migration and differentiation of mesenchymal cells, thereby activating the osteogenic ability of osteoblasts. Although studies on the action of HA during bone regeneration are being actively conducted, the optimal dose of HA required for bone regeneration remains unclear. Therefore, the purpose of this study was to elucidate the most effective HA dose for bone formation using a rat critical-size defect model.</p><p><strong>Methods: </strong>Thirty rats were randomly divided into 5 groups, with 6 rats in each group. An absorbable collagen sponge soaked with HA or saline was used to fill an 8-mm defect, which was then covered with a collagen membrane. Different treatments were performed for each group as follows: (1) saline control, (2) 1 mg/mL HA, (3) 25 mg/mL HA, (4) 50 mg/mL HA, or (5) 75 mg/mL HA. After a healing period of 4 weeks, micro-computed tomography and histological analysis were performed. The obtained values were analyzed using analysis of variance and the Tukey test (<i>P</i><0.05).</p><p><strong>Results: </strong>At week 4, the 75 mg/mL HA group had the highest bone volume/total volume ratio, new bone, and bone fill among the 5 groups, and these values were significantly different from those observed in the control group (<i>P</i><0.01) and 1 mg/mL HA group (<i>P</i><0.001). More active bone formation was observed in the higher-dose HA groups (25 mg/mL, 50 mg/mL, and 75 mg/mL HA), which included a large amount of woven bone.</p><p><strong>Conclusions: </strong>The 75 mg/mL HA group showed better bone formation than the other groups (1, 25, and 50 mg/mL HA and control).</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 4","pages":"259-268"},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a1/52/jpis-53-259.PMC10465808.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10120956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Efficacy of active noise-canceling headphones in patients undergoing ultrasonic scaling. 主动降噪耳机在超声洗洁术中的效果。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-08-01 DOI: 10.5051/jpis.2202200110
Jeong-Woong Kim, Bo-Ah Lee, Yu-Seon Park, Jinho Chung, Seong-Ho Choi, Young-Taek Kim
{"title":"Efficacy of active noise-canceling headphones in patients undergoing ultrasonic scaling.","authors":"Jeong-Woong Kim,&nbsp;Bo-Ah Lee,&nbsp;Yu-Seon Park,&nbsp;Jinho Chung,&nbsp;Seong-Ho Choi,&nbsp;Young-Taek Kim","doi":"10.5051/jpis.2202200110","DOIUrl":"https://doi.org/10.5051/jpis.2202200110","url":null,"abstract":"<p><strong>Purpose: </strong>Dental fear hinders patients from receiving appropriate dental treatment. In particular, the noise generated by high-speed air turbines and ultrasonic scalers can adversely affect patients. Many efforts have been made to reduce the discomfort caused by noise, but no methods are definitively recommended. The purpose of this study was to determine the efficacy of active noise-canceling (ANC) headphones in reducing the pain and discomfort associated with dental scaling.</p><p><strong>Methods: </strong>Fifty-five patients requiring scaling and root planing, aged ≥19 years and showing no auditory problems, were included. Scaling was performed for the bilateral maxillary molars and premolars while patients wore headphones, with ANC turned either on or off. The degree of noise and pain reduction in the on and off conditions were surveyed using a visual analog scale (VAS). The Wilcoxon signed-rank test was performed to compare noise- and pain-related discomfort with ANC turned on and off.</p><p><strong>Results: </strong>The sample included 28 men and 27 women with a mean age of 45.45±13.12 years. The average noise-related discomfort score was 3.84±2.12 and 2.95±1.99 when noise-canceling was turned off and on, respectively, with a statistically significant difference (<i>P</i><0.05). Similarly, the average pain-related discomfort score was 3.78±2.00 and 3.09±1.96 when noise-canceling was turned off and on, respectively, which was a statistically significant difference (<i>P</i><0.05).</p><p><strong>Conclusions: </strong>The use of ANC headphones seems to reduce the discomfort caused by noise and pain in patients undergoing scaling.</p><p><strong>Trial registration: </strong>Clinical Research Information Service Identifier: KCT0007093.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 4","pages":"269-282"},"PeriodicalIF":1.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6d/8f/jpis-53-269.PMC10465812.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10120955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of life, patient preferences, and implant survival and success of tapered implant-retained mandibular overdentures as a function of the attachment system. 生活质量,患者偏好,种植体存活和成功的锥形种植保留下颌覆盖义齿作为附着系统的功能。
IF 1.9 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2023-06-01 DOI: 10.5051/jpis.2105840292
Ilze Indriksone, Pauls Vitols, Viktors Avkstols, Linards Grieznis, Kaspars Stamers, Susy Linder, Michel Dard
{"title":"Quality of life, patient preferences, and implant survival and success of tapered implant-retained mandibular overdentures as a function of the attachment system.","authors":"Ilze Indriksone,&nbsp;Pauls Vitols,&nbsp;Viktors Avkstols,&nbsp;Linards Grieznis,&nbsp;Kaspars Stamers,&nbsp;Susy Linder,&nbsp;Michel Dard","doi":"10.5051/jpis.2105840292","DOIUrl":"https://doi.org/10.5051/jpis.2105840292","url":null,"abstract":"<p><strong>Purpose: </strong>A novel attachment system for implant-retained overdentures (IRODs) with novel material combinations for improved mechanical resilience and prosthodontic success (Novaloc) has been recently introduced as an alternative to an existing system (Locator). This study investigated whether differences between the Novaloc and Locator attachment systems translate into differences in implant survival, implant success, and patient-centered outcomes when applied in a real-world in-practice comparative setting in patients restored with mandibular IRODs supported by 2 interforaminal implants (2-IRODs).</p><p><strong>Methods: </strong>This prospective, intra-subject crossover comparison compared 20 patients who received 2 intra-foraminal bone level tapered implants restored with full acrylic overdentures using either the Locator or Novaloc attachment system. After 6 months of function, the attachment in the corresponding dentures was switched, and the definitive attachment system type was delivered based on the patient's preference after 12 months. For the definitive attachment system, implant survival was evaluated after 24 months. The primary outcomes of this study were oral health-related quality of life and patient preferences related to prosthetic and implant survival. Secondary outcomes included implant survival rate and success, prosthetic survival, perceived general health, and patient satisfaction.</p><p><strong>Results: </strong>Patient-centered outcomes and patient preferences between attachment systems were comparable, with relatively high overall patient satisfaction levels for both attachment systems. No difference in the prosthetic survival rate between study groups was detected. The implant survival rate over the follow-up period after 24 months in both groups was 100%.</p><p><strong>Conclusions: </strong>The results of this in-practice comparison indicate that both attachment systems represent comparable candidates for the prosthodontic retention of 2-IRODs. Both systems showed high rates of patient satisfaction and implant survival. The influence of material combinations of the retentive system on treatment outcomes between the tested systems remains inconclusive and requires further investigations.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"53 3","pages":"194-206"},"PeriodicalIF":1.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dc/00/jpis-53-194.PMC10315256.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9803748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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