L.E. Markovic , G. Hiremath , B.A. Scansen , H.B. Kellihan , C. Calkins , A.E. Coleman , S.S. Tjostheim , B. Tainter , K.M. Hodges , E. Cahill , M. Carter , D.W. Kim
{"title":"Comparative transcatheter occlusion of patent ductus arteriosus: multicenter collaborative study across pediatric and veterinary cardiology centers","authors":"L.E. Markovic , G. Hiremath , B.A. Scansen , H.B. Kellihan , C. Calkins , A.E. Coleman , S.S. Tjostheim , B. Tainter , K.M. Hodges , E. Cahill , M. Carter , D.W. Kim","doi":"10.1016/j.jvc.2024.08.008","DOIUrl":"10.1016/j.jvc.2024.08.008","url":null,"abstract":"<div><h3>Introduction/Objective</h3><div>Transcatheter therapeutics have revolutionized treatment of patent ductus arteriosus (PDA). Greater understanding of corrective interventions across species can advance best practices, protocols, and outcomes while minimizing adverse events. The objective of this study was to describe characteristics and outcomes in children and dogs undergoing transcatheter PDA occlusion.</div></div><div><h3>Animals, Materials and Methods</h3><div>This was a multicenter, retrospective cohort study from two pediatric and three veterinary centers. Demographics, procedural characteristics, and outcomes were assessed.</div></div><div><h3>Results</h3><div>Data included 202 children and 106 dogs treated from July 2019 to June 2021. Forty-five (23%) children and 19 (18%) dogs had congestive heart failure prior to catheterization. Transvenous and transarterial approaches for deployment were most used in children and dogs, respectively. All children had percutaneous vascular access compared to 17 (16%) dogs. Intraprocedural anticoagulation was standard for children (100% of 165 reported), but not for dogs (2/103). The median (interquartile range) pulmonary ostium diameter in children was 2.2 mm (1.5–3.0 mm) and 3.0 mm (2.0–4.2 mm) in dogs when all body sizes were considered (P<0.001). Amplatzer™ Duct Occluder was most commonly used in children (64/202, 32%); the Amplatz® Canine Duct Occluder was used in dogs (96/100, 96%). Closure was manual compression in all children, whereas vessel ligation was most used in dogs (74/104, 73%). Successful device deployment was achieved in 197 (98%) children and 98 (93%) dogs (P=0.03). Major reasons for failure included device embolization in six (2.9%) children and PDA morphology concerns in four (3.8%) dogs.</div></div><div><h3>Conclusions</h3><div>Transcatheter PDA occlusion is successful in children and dogs. Study data might be useful for optimizing transcatheter therapeutics and animal models for interventional cardiology.</div></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"56 ","pages":"Pages 72-83"},"PeriodicalIF":1.5,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Lichtenberger , E. Côté , S.D. Forney , K.A. Barrett , S.J. Ettinger
{"title":"Cardiac biomarker profiles in dogs with naturally occurring precapillary pulmonary hypertension","authors":"J. Lichtenberger , E. Côté , S.D. Forney , K.A. Barrett , S.J. Ettinger","doi":"10.1016/j.jvc.2024.08.007","DOIUrl":"10.1016/j.jvc.2024.08.007","url":null,"abstract":"<div><h3>Introduction/Objectives</h3><div>This study evaluated circulating amino-terminal pro-B-type natriuretic peptide (NT-proBNP), amino-terminal pro-A-type natriuretic peptide (NT-proANP), and cardiac troponin I (cTnI) concentrations in dogs with precapillary pulmonary hypertension (Pre-PH) and control dogs with respiratory clinical signs but no Pre-PH.</div></div><div><h3>Animals</h3><div>Twenty-six dogs (17 affected, and 9 controls) were involved in the study.</div></div><div><h3>Materials and Methods</h3><div>This was a sub-study of a large prospective single-center observational study. Dogs underwent blood sample collection, physical examination, and echocardiographic evaluation. Pre-PH was diagnosed when a calculated right ventricular-to-right atrial pressure gradient (RV:RA PG) measuring ≥40 mmHg was identified echocardiographically, barring right ventricular outflow obstruction and/or left-sided cardiac disease.</div></div><div><h3>Results</h3><div>Two, nine, and six dogs had mild, moderate, and severe Pre-PH, respectively. Plasma concentrations of NT-proBNP, NT-proANP, and cTnI were significantly higher in the affected group than in the control group (P=0.020, P=0.009, P=0.011, respectively). There was a positive correlation between RV:RA PG and NT-proBNP (r = 0.52), NT-proANP (r = 0.54), and cTnI (r = 0.67) concentrations.</div></div><div><h3>Discussion</h3><div>Pre-PH should be included in the differential diagnosis list of elevated cardiac biomarker concentrations in dogs with respiratory signs.</div></div><div><h3>Study Limitations</h3><div>Strict selection criteria reduced group sizes. There were rare missing data points. The diagnosis of Pre-PH was obtained from Doppler echocardiographic RV:RA PG. The disease process causing Pre-PH was not evaluated histopathologically.</div></div><div><h3>Conclusions</h3><div>Circulating cardiac biomarker concentrations are increased in dogs with Pre-PH and there is a positive correlation between RV:RA PG and NT-proBNP, NT-proANP, and cTnI concentrations.</div></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"56 ","pages":"Pages 56-64"},"PeriodicalIF":1.5,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1760273424000808/pdfft?md5=a73935379b3612d6ee471dae2333b733&pid=1-s2.0-S1760273424000808-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142182902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Ferasin , H. Ferasin , J. Farminer , E. Hudson , K. Lamb
{"title":"Diagnostic value of a point-of-care cardiac troponin-I assay (i-STAT®) for clinical application in canine and feline cardiology","authors":"L. Ferasin , H. Ferasin , J. Farminer , E. Hudson , K. Lamb","doi":"10.1016/j.jvc.2024.07.006","DOIUrl":"10.1016/j.jvc.2024.07.006","url":null,"abstract":"<div><h3><strong>Introduction/Objectives</strong></h3><p>This study was performed to evaluate the diagnostic value and net benefits, including cost-effectiveness, of a point-of-care analyser (i-STAT®) for measurement of cardiac troponin I (cTnI) in dogs and cats.</p></div><div><h3><strong>Animals, Materials and Methods</strong></h3><p>120 dogs and 120 cats presented with signs of cardiac disease and suspected myocardial insult on cardiac assessment. This was a validation study expressed as agreement between the i-STAT® analyser and two common commercial reference methods (IMMULITE® 2000 and ACCESS® hsTnI).</p></div><div><h3><strong>Results</strong></h3><p>The comparison between methods showed a negative bias between the i–STAT® and the two commercial cTnI assays. The bias was more evident when the i-STAT® values were compared to the traditional cTnI assay (IMMULITE® 2000), with a calculated difference of −1.14 ng/mL (dogs) and −0.96 ng/mL (cats). However, the bias was distinctly lower when the i-STAT® measurements were compared to the high-sensitivity cTnI assay (ACCESS®), namely −0.3 ng/mL in dogs and −0.17 in cats.</p></div><div><h3><strong>Discussion</strong></h3><p>The i-STAT® method can reliably detect normal, low and elevated cTnI values, which is fundamental to differentiate pets with and without myocardial damage and, with the rapid availability of results, this confirms the clinical utility of the i-STAT® method.</p></div><div><h3>Conclusions</h3><p>cTnI concentrations measured with the i-STAT® have good comparability with those obtained with both commercial assays for low and elevated cTnI values. However, results should be cautiously interpreted for high troponin values, especially if a strict cut-off value is adopted for diagnostic or prognostic purposes in critical clinical conditions, such as myocarditis or acute myocardial ischaemia.</p></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"56 ","pages":"Pages 35-43"},"PeriodicalIF":1.5,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142182903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ruptured left sinus of Valsalva aneurysm into the left atrium in a dog","authors":"S.M. Fultz , H.B. Kellihan , P. Nagpal","doi":"10.1016/j.jvc.2024.08.006","DOIUrl":"10.1016/j.jvc.2024.08.006","url":null,"abstract":"<div><p>A dog with immune-mediated thrombocytopenia and a new heart murmur had an echocardiogram in 2016 and was found to have a suspected aorto-left atrial fistula. The echocardiogram findings remained relatively static from 2016 to 2022. This report highlights the use of cardiac-gated computed tomography angiography to allow further understanding of a complex anomaly in a patient with a ruptured sinus of Valsalva aneurysm causing a fistulous connection with the left atrium.</p></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"56 ","pages":"Pages 1-7"},"PeriodicalIF":1.5,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142182904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Cala , L. Ferasin , H. Ferasin , O. Domenech , M. Bini , V. Valenti , L. Venco
{"title":"Transvenous closure of patent ductus arteriosus with Nit-Occlud® PDA occlusion system in 13 dogs weighing less than 3 kg","authors":"A. Cala , L. Ferasin , H. Ferasin , O. Domenech , M. Bini , V. Valenti , L. Venco","doi":"10.1016/j.jvc.2024.08.005","DOIUrl":"10.1016/j.jvc.2024.08.005","url":null,"abstract":"<div><h3>Introduction</h3><p>Successful closure of patent ductus arteriosus (PDA) can be obtained with surgical ligation or with occlusion via minimally invasive per-catheter techniques. This study was performed to assess feasibility and effectiveness of transjugular PDA occlusion in dogs weighing < 3 kg with a device called Nit-Occlud® PDA.</p></div><div><h3>Animals</h3><p>Thirteen client-owned dogs.</p></div><div><h3>Materials and Methods</h3><p>This was a retrospective study. Clinical records of dogs that underwent PDA occlusion with a Nit-Occlud® PDA were reviewed. Data collection included patients’ signalment, clinical findings, pre- and post-procedure echocardiographic measurements, device size, procedure time and clinical outcome.</p></div><div><h3>Results</h3><p>The median age of these patients was six months (2.5-38.0 months), with a mean body weight of 2.44 ± 0.43 kg. The mean minimal ductal diameter (MDD) was 1.82 ± 0.43 mm, while the mean ampulla diameter (AD) was 5.51 ± 1.89 mm. Duct closure was successful in 12 cases. Minimal or no residual shunt was observed on echocardiography prior to device release. In one dog, the device was not released owing to unsatisfactory occlusion, prompting an alternative occlusion method. Follow-up echocardiographic examinations showed complete ductal closure and reversed cardiac remodelling in all cases where the device was successfully released.</p></div><div><h3>Discussion</h3><p>The Nit-Occlud® is deployed through a delivery system with an outer diameter of 4 F or 5 F, which makes this solution particularly attractive in patients where vascular access is challenging or unfeasible due to the small size of their vessels.</p></div><div><h3>Conclusions</h3><p>The Nit-Occlud® PDA appears a feasible and effective occlusion system in small patients weighing <3 kg.</p></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"56 ","pages":"Pages 23-34"},"PeriodicalIF":1.5,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142182912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Aherne , M. Borgarelli, G. Menciotti, S.M. Lahmers, J.A. Abbott
{"title":"Evaluation of right ventricular function using conventional and real-time three-dimensional echocardiography in healthy dogs and dogs with myxomatous mitral valve disease","authors":"M. Aherne , M. Borgarelli, G. Menciotti, S.M. Lahmers, J.A. Abbott","doi":"10.1016/j.jvc.2024.08.003","DOIUrl":"10.1016/j.jvc.2024.08.003","url":null,"abstract":"<div><h3>Introduction/Objectives</h3><p>To compare conventional and three-dimensional (3D) echocardiographic indices of right ventricular (RV) systolic function in dogs with various stages of myxomatous mitral valve disease (MMVD), classified according to the 2009 guidelines of the American College of Veterinary Internal Medicine (ACVIM), with those from normal dogs.</p></div><div><h3>Animals</h3><p>Seventy-eight unsedated dogs (22 healthy controls, 23 ACVIM stage B1 MMVD, 20 ACVIM stage B2 MMVD, and 13 ACVIM stage C MMVD) were included in the study.</p></div><div><h3>Materials and methods</h3><p>All dogs underwent conventional and 3D echocardiography. Three-dimensional RV end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF) were recorded. Right ventricular EDV, ESV, and SV were indexed to bodyweight. Echocardiographic variables were compared across groups using a Kruskal–Wallis test with subsequent post hoc analysis using Dunn's method for multiple comparisons between groups. A P-value of <0.05 was considered significant.</p></div><div><h3>Results</h3><p>Right ventricular EDV was smaller in stage B1 (P=0.012), stage B2 (P=0.035), and stage C (P=0.004) dogs than in controls. Stage B2 (P=0.003) and stage C (P<0.001) dogs had smaller RV ESV than controls. Stage B1 dogs had smaller RV SV than controls (P=0.012). Right ventricular EF was greater in stage C dogs than in controls (P=0.003) and in stage B1 (P=0.017) dogs.</p></div><div><h3>Conclusions</h3><p>Several 3D echocardiographic indices of RV systolic function differ between dogs with advanced MMVD when compared with normal dogs. Further investigation is required to determine if these differences have clinical implications.</p></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"56 ","pages":"Pages 8-22"},"PeriodicalIF":1.5,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142182905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Yan , C. Evered , S. Raheb , B. Lillie , S. Fonfara
{"title":"Ventricular cardiac hemangiosarcoma with brain metastases in a dog","authors":"J. Yan , C. Evered , S. Raheb , B. Lillie , S. Fonfara","doi":"10.1016/j.jvc.2024.08.004","DOIUrl":"10.1016/j.jvc.2024.08.004","url":null,"abstract":"<div><p>An 11-year-old, female, spayed, soft-coated Wheaten terrier presented for acute onset of neurological signs. On presentation, neurological examination showed right thoracic and pelvic limb proprioceptive deficits, absent right menace reflex, and weak right nasal septum response. A left thalamocortical lesion was localized. On thoracic auscultation, an arrhythmia was noted, and electrocardiography showed frequent ventricular premature complexes and rare runs of ventricular tachycardia. Echocardiography identified an interventricular septal mass extending into the lumen of the left ventricle. Thalamocortical metastasis secondary to the cardiac mass was suspected to be the cause of the patient's neurological signs. Humane euthanasia was elected by the owner due to the patients clinical status and poor prognosis. A postmortem examination diagnosed hemangiosarcoma of the interventricular septum, the right ventricular free wall, and left ventricular free wall. The left ventricle adjacent to the paraconal groove showed myocardial necrosis and inflammation. Metastases to the brain and secondary intracranial hemorrhage were found which were suspected to be the cause of the antemortem neurological signs. Concurrent pulmonary and hepatic metastases were noted. This report describes a rare presentation of an intracardiac hemangiosarcoma of the interventricular septum, right ventricle, and left ventricle in a patient presenting with neurological signs.</p></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"55 ","pages":"Pages 32-37"},"PeriodicalIF":1.5,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142097487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Machado, C. Partington, J. Silva, L. Gardner, J. Novo Matos
{"title":"Left atrial fractional shortening obtained from two different echocardiographic views in cats is not interchangeable","authors":"A. Machado, C. Partington, J. Silva, L. Gardner, J. Novo Matos","doi":"10.1016/j.jvc.2024.08.002","DOIUrl":"10.1016/j.jvc.2024.08.002","url":null,"abstract":"<div><h3>Introduction/objectives</h3><p>Left atrial fractional shortening (LAFS%) is a widely used index of left atrial systolic function in cats that has been shown to predict development of hypertrophic cardiomyopathy (HCM) and cardiac mortality. It can be determined by two methods: from an M-mode right parasternal short-axis view (LAFS%<sup>RPSA-MM</sup>) or two-dimensional right parasternal long-axis four-chamber view (LAFS%<sup>RPLA-2D</sup>). We aimed to assess the agreement between LAFS%<sup>RPSA-MM</sup> and LAFS%<sup>RPLA-2D</sup> in cats and to evaluate the correlation between LAFS%<sup>RPSA-MM</sup> and LAFS%<sup>RPLA-2D</sup> and left ventricular systolic performance.</p></div><div><h3>Animals, materials, and methods</h3><p>One hundred and seventeen cats were enrolled in the study: 40 control, 41 HCM stage B (asymptomatic), and 36 HCM stage C (symptomatic) cats. This was a retrospective case–control study. Bland–Altman analysis was used to assess agreement between LAFS%<sup>RPSA-MM</sup> and LAFS%<sup>RPLA-2D</sup> across the whole cohort and in cats with asymptomatic and symptomatic HCM. Correlation analysis was used to assess associations between LAFS% methods and forward aortic flow, left ventricular fractional shortening, and aortic root motion.</p></div><div><h3>Results</h3><p>The LAFS% determined by LAFS%<sup>RPSA-MM</sup> and LAFS%<sup>RPLA-2D</sup> was similar (P=0.8), but Bland–Altman analysis showed wide limits of agreement between methods. There was a good correlation between LAFS%<sup>RPSA-MM</sup> and LAFS%<sup>RPLA-2D</sup> and aortic root motion (r = 0.78 and r = 0.71, respectively) and a fair correlation with left ventricular fractional shortening (r = 0.31 and r = 0.29, respectively). None of the methods showed a correlation with indices of aortic flow.</p></div><div><h3>Conclusions</h3><p>Our study suggests a poor agreement between LAFS%<sup>RPSA-MM</sup> and LAFS%<sup>RPLA-2D</sup>, and thus, these methods should not be used interchangeably. Both echocardiographic methods showed good correlation with aortic root motion.</p></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"55 ","pages":"Pages 38-47"},"PeriodicalIF":1.5,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1760273424000717/pdfft?md5=9f40f6f496b486c2d3ea6e52cffcdb1a&pid=1-s2.0-S1760273424000717-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantification of respiratory sinus arrhythmia in control dogs and in dogs with various severity classes of myxomatous mitral valve disease","authors":"R.A. Baisan , C.A. Turcu , L.M. Bilboc , M.C. Maftei , V. Vulpe , D.G. Ohad","doi":"10.1016/j.jvc.2024.08.001","DOIUrl":"10.1016/j.jvc.2024.08.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Loss of respiratory sinus arrhythmia (RSA) is a negative prognostic factor in dogs with myxomatous mitral valve disease (MMVD). The aim of this study was to calculate the percentage (%) of RSA in healthy dogs and dogs in various MMVD classes.</p></div><div><h3>Animals</h3><p>Control and MMVD dogs were prospectively included in the study.</p></div><div><h3>Materials and methods</h3><p>Respiratory sinus arrhythmia was calculated from a dual channel electrocardiography and breathing curve recording using the peak-to-trough method, in percent of the average heart rate.</p></div><div><h3>Results</h3><p>One hundred and forty-nine dogs were studied, including 24 control and 125 MMVD dogs of different severity classes. An overall %RSA decrease was documented with increasing disease severity up to the Ca class along with a relative %RSA increase in the Cc class. The %RSA magnitude differed between B2 and Ca (P<0.001), and between Ca and Cc (P = 0.001) groups, respectively. The %RSA showed a medium negative correlation with the La:Ao ratio (r2 = −0.568, P<0.001) and with the E-wave velocity (r2 = −0.561, P<0.001).</p></div><div><h3>Discussions</h3><p>A decrease in %RSA was shown with increased disease severity up to acute congestive heart failure (CHF). Dogs receiving cardiac therapy leading to stabilized CHF might restore their ability to exhibit RSA, often revealing a higher %RSA compared to those in acute CHF.</p></div><div><h3>Study limitations</h3><p>Low number of respiratory cycles for analysis. Therapy effect not evaluated.</p></div><div><h3>Conclusions</h3><p>The findings of this study can serve as the basis for future risk stratification and carry the potential of proving an additional clinical marker for diagnostic and therapeutic decisions making when managing MMVD dogs.</p></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"55 ","pages":"Pages 48-56"},"PeriodicalIF":1.5,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142128830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Twenty-five years of Journal of Veterinary Cardiology: when it all started","authors":"C. Lombard, C. Amberger","doi":"10.1016/j.jvc.2024.07.003","DOIUrl":"10.1016/j.jvc.2024.07.003","url":null,"abstract":"","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"54 ","pages":"Pages 82-85"},"PeriodicalIF":1.5,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141775208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}