发布求助
文献互助 智能选刊 最新文献

Annual Review of Virology最新文献

筛选
英文 中文
Impact of the Microbiota on Viral Infections. 微生物群对病毒感染的影响。
IF 8.1 1区 医学
Annual Review of Virology Pub Date : 2023-09-29 Epub Date: 2023-04-18 DOI: 10.1146/annurev-virology-111821-115754
Danielle E Campbell, Yuhao Li, Harshad Ingle, Megan T Baldridge
{"title":"Impact of the Microbiota on Viral Infections.","authors":"Danielle E Campbell, Yuhao Li, Harshad Ingle, Megan T Baldridge","doi":"10.1146/annurev-virology-111821-115754","DOIUrl":"10.1146/annurev-virology-111821-115754","url":null,"abstract":"<p><p>The mammalian gastrointestinal tract (GIT) hosts a diverse and highly active microbiota composed of bacteria, eukaryotes, archaea, and viruses. Studies of the GIT microbiota date back more than a century, although modern techniques, including mouse models, sequencing technology, and novel therapeutics in humans, have been foundational to our understanding of the roles of commensal microbes in health and disease. Here, we review the impacts of the GIT microbiota on viral infection, both within the GIT and systemically. GIT-associated microbes and their metabolites alter the course of viral infection through a variety of mechanisms, including direct interactions with virions, alteration of the GIT landscape, and extensive regulation of innate and adaptive immunity. Mechanistic understanding of the full breadth of interactions between the GIT microbiota and the host is still lacking in many ways but will be vital for the development of novel therapeutics for viral and nonviral diseases alike.</p>","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":" ","pages":"371-395"},"PeriodicalIF":8.1,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10000932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cross-Kingdom Interactions Between Plant and Fungal Viruses. 植物和真菌病毒之间的跨王国相互作用。
IF 11.3 1区 医学
Annual Review of Virology Pub Date : 2023-09-29 Epub Date: 2023-07-05 DOI: 10.1146/annurev-virology-111821-122539
Ida Bagus Andika, Mengyuan Tian, Ruiling Bian, Xinran Cao, Ming Luo, Hideki Kondo, Liying Sun
{"title":"Cross-Kingdom Interactions Between Plant and Fungal Viruses.","authors":"Ida Bagus Andika,&nbsp;Mengyuan Tian,&nbsp;Ruiling Bian,&nbsp;Xinran Cao,&nbsp;Ming Luo,&nbsp;Hideki Kondo,&nbsp;Liying Sun","doi":"10.1146/annurev-virology-111821-122539","DOIUrl":"10.1146/annurev-virology-111821-122539","url":null,"abstract":"<p><p>The large genetic and structural divergences between plants and fungi may hinder the transmission of viruses between these two kingdoms to some extent. However, recent accumulating evidence from virus phylogenetic analyses and the discovery of naturally occurring virus cross-infection suggest the occurrence of past and current transmissions of viruses between plants and plant-associated fungi. Moreover, artificial virus inoculation experiments showed that diverse plant viruses can multiply in fungi and vice versa. Thus, virus cross-infection between plants and fungi may play an important role in the spread, emergence, and evolution of both plant and fungal viruses and facilitate the interaction between them. In this review, we summarize current knowledge related to cross-kingdom virus infection in plants and fungi and further discuss the relevance of this new virological topic in the context of understanding virus spread and transmission in nature as well as developing control strategies for crop plant diseases.</p>","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":" ","pages":"119-138"},"PeriodicalIF":11.3,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10132341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Small but Highly Versatile: The Viral Accessory Protein Vpu. 小但高度通用：病毒辅助蛋白Vpu。
IF 11.3 1区 医学
Annual Review of Virology Pub Date : 2023-09-29 Epub Date: 2023-07-05 DOI: 10.1146/annurev-virology-111821-100816
Meta Volcic, Lisa Wiesmüller, Frank Kirchhoff
{"title":"Small but Highly Versatile: The Viral Accessory Protein Vpu.","authors":"Meta Volcic,&nbsp;Lisa Wiesmüller,&nbsp;Frank Kirchhoff","doi":"10.1146/annurev-virology-111821-100816","DOIUrl":"10.1146/annurev-virology-111821-100816","url":null,"abstract":"<p><p>Human and simian immunodeficiency viruses (HIVs and SIVs, respectively) encode several small proteins (Vif, Vpr, Nef, Vpu, and Vpx) that are called accessory because they are not generally required for viral replication in cell culture. However, they play complex and important roles for viral immune evasion and spread in vivo. Here, we discuss the diverse functions and the relevance of the viral protein U (Vpu) that is expressed from a bicistronic RNA during the late stage of the viral replication cycle and found only in HIV-1 and closely related SIVs. It is well established that Vpu counteracts the restriction factor tetherin, mediates degradation of the primary viral CD4 receptors, and inhibits activation of the transcription factor nuclear factor kappa B. Recent studies identified additional activities and provided new insights into the sophisticated mechanisms by which Vpu enhances and prolongs the release of fully infectious viral particles. In addition, it has been shown that Vpu prevents superinfection not only by degrading CD4 but also by modulating DNA repair mechanisms to promote degradation of nuclear viral complementary DNA in cells that are already productively infected.</p>","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":" ","pages":"243-259"},"PeriodicalIF":11.3,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10132342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Regulation of Immune Homeostasis, Inflammation, and HIV Persistence by the Microbiome, Short-Chain Fatty Acids, and Bile Acids. 微生物组、短链脂肪酸和胆汁酸对免疫稳态、炎症和HIV持续性的调节。
IF 11.3 1区 医学
Annual Review of Virology Pub Date : 2023-09-29 DOI: 10.1146/annurev-virology-040323-082822
Ana Beatriz Enriquez, Felipe Ten Caten, Khader Ghneim, Rafick-Pierre Sekaly, Ashish Arunkumar Sharma
{"title":"Regulation of Immune Homeostasis, Inflammation, and HIV Persistence by the Microbiome, Short-Chain Fatty Acids, and Bile Acids.","authors":"Ana Beatriz Enriquez,&nbsp;Felipe Ten Caten,&nbsp;Khader Ghneim,&nbsp;Rafick-Pierre Sekaly,&nbsp;Ashish Arunkumar Sharma","doi":"10.1146/annurev-virology-040323-082822","DOIUrl":"10.1146/annurev-virology-040323-082822","url":null,"abstract":"<p><p>Despite antiretroviral therapy (ART), people living with human immunodeficiency virus (HIV) (PLWH) continue to experience chronic inflammation and immune dysfunction, which drives the persistence of latent HIV and prevalence of clinical comorbidities. Elucidating the mechanisms that lead to suboptimal immunity is necessary for developing therapeutics that improve the quality of life of PLWH. Although previous studies have found associations between gut dysbiosis and immune dysfunction, the cellular/molecular cascades implicated in the manifestation of aberrant immune responses downstream of microbial perturbations in PLWH are incompletely understood. Recent literature has highlighted that two abundant metabolite families, short-chain fatty acids (SCFAs) and bile acids (BAs), play a crucial role in shaping immunity. These metabolites can be produced and/or modified by bacterial species that make up the gut microbiota and may serve as the causal link between changes to the gut microbiome, chronic inflammation, and immune dysfunction in PLWH. In this review, we discuss our current understanding of the role of the microbiome on HIV acquisition and latent HIV persistence despite ART. Further, we describe cellular/molecular cascades downstream of SCFAs and BAs that drive innate or adaptive immune responses responsible for promoting latent HIV persistence in PLWH. This knowledge can be used to advance HIV cure efforts.</p>","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":"10 1","pages":"397-422"},"PeriodicalIF":11.3,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41136453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Viral Evolution Shaped by Host Proteostasis Networks. 宿主蛋白质稳定网络塑造的病毒进化。
IF 8.1 1区 医学
Annual Review of Virology Pub Date : 2023-09-29 Epub Date: 2023-04-18 DOI: 10.1146/annurev-virology-100220-112120
Jimin Yoon, Jessica E Patrick, C Brandon Ogbunugafor, Matthew D Shoulders
{"title":"Viral Evolution Shaped by Host Proteostasis Networks.","authors":"Jimin Yoon, Jessica E Patrick, C Brandon Ogbunugafor, Matthew D Shoulders","doi":"10.1146/annurev-virology-100220-112120","DOIUrl":"10.1146/annurev-virology-100220-112120","url":null,"abstract":"<p><p>Understanding the factors that shape viral evolution is critical for developing effective antiviral strategies, accurately predicting viral evolution, and preventing pandemics. One fundamental determinant of viral evolution is the interplay between viral protein biophysics and the host machineries that regulate protein folding and quality control. Most adaptive mutations in viruses are biophysically deleterious, resulting in a viral protein product with folding defects. In cells, protein folding is assisted by a dynamic system of chaperones and quality control processes known as the proteostasis network. Host proteostasis networks can determine the fates of viral proteins with biophysical defects, either by assisting with folding or by targeting them for degradation. In this review, we discuss and analyze new discoveries revealing that host proteostasis factors can profoundly shape the sequence space accessible to evolving viral proteins. We also discuss the many opportunities for research progress proffered by the proteostasis perspective on viral evolution and adaptation.</p>","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":" ","pages":"77-98"},"PeriodicalIF":8.1,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10543606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9412387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Introduction: Virology in the Headlines. 导言:病毒学在头条新闻。
IF 11.3 1区 医学
Annual Review of Virology Pub Date : 2022-09-29 DOI: 10.1146/annurev-vi-09-071222-100001
Lynn W Enquist, Daniel DiMaio, Terence S Dermody
{"title":"Introduction: Virology in the Headlines.","authors":"Lynn W Enquist,&nbsp;Daniel DiMaio,&nbsp;Terence S Dermody","doi":"10.1146/annurev-vi-09-071222-100001","DOIUrl":"https://doi.org/10.1146/annurev-vi-09-071222-100001","url":null,"abstract":"","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":" ","pages":"i-ii"},"PeriodicalIF":11.3,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40383119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Viruses in Identifying and Analyzing RNA Silencing. 病毒在鉴定和分析RNA沉默中的作用。
IF 8.1 1区 医学
Annual Review of Virology Pub Date : 2022-09-29 Epub Date: 2022-06-02 DOI: 10.1146/annurev-virology-091919-064218
David C Baulcombe
{"title":"The Role of Viruses in Identifying and Analyzing RNA Silencing.","authors":"David C Baulcombe","doi":"10.1146/annurev-virology-091919-064218","DOIUrl":"10.1146/annurev-virology-091919-064218","url":null,"abstract":"<p><p>Adaptive antiviral immunity in plants is an RNA-based mechanism in which small RNAs derived from both strands of the viral RNA are guides for an Argonaute (AGO) nuclease. The primed AGO specifically targets and silences the viral RNA. In plants this system has diversified to involve mobile small interfering RNAs (siRNAs), an amplification system involving secondary siRNAs and targeting mechanisms involving DNA methylation. Most, if not all, plant viruses encode multifunctional proteins that are suppressors of RNA silencing that may also influence the innate immune system and fine-tune the virus-host interaction. Animal viruses similarly trigger RNA silencing, although it may be masked in differentiated cells by the interferon system and by the action of the virus-encoded suppressor proteins. There is huge potential for RNA silencing to combat viral disease in crops, farm animals, and people, although there are complications associated with the various strategies for siRNA delivery including transgenesis. Alternative approaches could include using breeding or small molecule treatment to enhance the inherent antiviral capacity of infected cells.</p>","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":"9 1","pages":"353-373"},"PeriodicalIF":8.1,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10580051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RNA-Based Vaccination of Plants for Control of Viruses. 基于rna的植物预防病毒的研究。
IF 11.3 1区 医学
Annual Review of Virology Pub Date : 2022-09-29 DOI: 10.1146/annurev-virology-091919-073708
Andreas E Voloudakis, Athanasios Kaldis, Basavaprabhu L Patil
{"title":"RNA-Based Vaccination of Plants for Control of Viruses.","authors":"Andreas E Voloudakis,&nbsp;Athanasios Kaldis,&nbsp;Basavaprabhu L Patil","doi":"10.1146/annurev-virology-091919-073708","DOIUrl":"https://doi.org/10.1146/annurev-virology-091919-073708","url":null,"abstract":"<p><p>Plant viruses cause nearly half of the emerging plant diseases worldwide, contributing to 10-15% of crop yield losses. Control of plant viral diseases is mainly accomplished by extensive chemical applications targeting the vectors (i.e., insects, nematodes, fungi) transmitting these viruses. However, these chemicals have a significant negative effect on human health and the environment. RNA interference is an endogenous, cellular, sequence-specific RNA degradation mechanism in eukaryotes induced by double-stranded RNA molecules that has been exploited as an antiviral strategy through transgenesis. Because genetically modified crop plants are not accepted for cultivation in several countries globally, there is an urgent demand for alternative strategies. This has boosted research on exogenous application of the RNA-based biopesticides that are shown to exhibit significant protective effect against viral infections. Such environment-friendly and efficacious antiviral agents for crop protection will contribute to global food security, without adverse effects on human health.</p>","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":" ","pages":"521-548"},"PeriodicalIF":11.3,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40383120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
A Trait-Based Approach to Predicting Viral Host-Range Evolvability. 基于性状的病毒宿主进化预测方法。
IF 11.3 1区 医学
Annual Review of Virology Pub Date : 2022-09-29 DOI: 10.1146/annurev-virology-091919-092003
Hannah M Strobel, Elizabeth C Stuart, Justin R Meyer
{"title":"A Trait-Based Approach to Predicting Viral Host-Range Evolvability.","authors":"Hannah M Strobel,&nbsp;Elizabeth C Stuart,&nbsp;Justin R Meyer","doi":"10.1146/annurev-virology-091919-092003","DOIUrl":"https://doi.org/10.1146/annurev-virology-091919-092003","url":null,"abstract":"<p><p>Predicting the evolution of virus host range has proven to be extremely difficult, in part because of the sheer diversity of viruses, each with unique biology and ecological interactions. We have not solved this problem, but to make the problem more tractable, we narrowed our focus to three traits intrinsic to all viruses that may play a role in host-range evolvability: mutation rate, recombination rate, and phenotypic heterogeneity. Although each trait should increase evolvability, they cannot do so unbounded because fitness trade-offs limit the ability of all three traits to maximize evolvability. By examining these constraints, we can begin to identify groups of viruses with suites of traits that make them especially concerning, as well as ecological and environmental conditions that might push evolution toward accelerating host-range expansion.</p>","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":" ","pages":"139-156"},"PeriodicalIF":11.3,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40383121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
APOBEC3: Friend or Foe in Human Papillomavirus Infection and Oncogenesis? APOBEC3：人类乳头瘤病毒感染和肿瘤发生中的朋友还是敌人？
IF 11.3 1区 医学
Annual Review of Virology Pub Date : 2022-09-29 Epub Date: 2022-06-07 DOI: 10.1146/annurev-virology-092920-030354
Cody J Warren, Mario L Santiago, Dohun Pyeon
{"title":"APOBEC3: Friend or Foe in Human Papillomavirus Infection and Oncogenesis?","authors":"Cody J Warren, Mario L Santiago, Dohun Pyeon","doi":"10.1146/annurev-virology-092920-030354","DOIUrl":"10.1146/annurev-virology-092920-030354","url":null,"abstract":"<p><p>Human papillomavirus (HPV) infection is a causative agent of multiple human cancers, including cervical and head and neck cancers. In these HPV-positive tumors, somatic mutations are caused by aberrant activation of DNA mutators such as members of the apolipoprotein B messenger RNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3) family of cytidine deaminases. APOBEC3 proteins are most notable for their restriction of various viruses, including anti-HPV activity. However, the potential role of APOBEC3 proteins in HPV-induced cancer progression has recently garnered significant attention. Ongoing research stems from the observations that elevated APOBEC3 expression is driven by HPV oncogene expression and that APOBEC3 activity is likely a significant contributor to somatic mutagenesis in HPV-positive cancers. This review focuses on recent advances in the study of APOBEC3 proteins and their roles in HPV infection and HPV-driven oncogenesis. Further, we discuss critical gaps and unanswered questions in our understanding of APOBEC3 in virus-associated cancers.</p>","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":"9 1","pages":"375-395"},"PeriodicalIF":11.3,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637027/pdf/nihms-1845347.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41180317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信