Annual Review of Virology最新文献_第7页

Viral G Protein-Coupled Receptors Encoded by β- and γ-Herpesviruses. β-和γ-疱疹病毒编码的病毒G蛋白偶联受体

IF 11.3 1区医学

Annual Review of Virology Pub Date : 2022-09-29 DOI: 10.1146/annurev-virology-100220-113942

Mette M Rosenkilde, Naotaka Tsutsumi, Julius M Knerr, Dagmar F Kildedal, K Christopher Garcia

引用次数: 10

Nuclear Capsid Uncoating and Reverse Transcription of HIV-1. HIV-1的核衣壳剥离和逆转录。

IF 11.3 1区医学

Annual Review of Virology Pub Date : 2022-06-15 DOI: 10.1146/annurev-virology-020922-110929

Thorsten G. Müller, V. Zila, B. Müller, H. Kräusslich

{"title":"Nuclear Capsid Uncoating and Reverse Transcription of HIV-1.","authors":"Thorsten G. Müller, V. Zila, B. Müller, H. Kräusslich","doi":"10.1146/annurev-virology-020922-110929","DOIUrl":"https://doi.org/10.1146/annurev-virology-020922-110929","url":null,"abstract":"After cell entry, human immunodeficiency virus type 1 (HIV-1) replication involves reverse transcription of the RNA genome, nuclear import of the subviral complex without nuclear envelope breakdown, and integration of the viral complementary DNA into the host genome. Here, we discuss recent evidence indicating that completion of reverse transcription and viral genome uncoating occur in the nucleus rather than in the cytoplasm, as previously thought, and suggest a testable model for nuclear import and uncoating. Multiple recent studies indicated that the cone-shaped capsid, which encases the genome and replication proteins, not only serves as a reaction container for reverse transcription and as a shield from innate immune sensors but also may constitute the elusive HIV-1 nuclear import factor. Rupture of the capsid may be triggered in the nucleus by completion of reverse transcription, by yet-unknown nuclear factors, or by physical damage, and it appears to occur in close temporal and spatial association with the integration process. Expected final online publication date for the Annual Review of Virology, Volume 9 is September 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":" ","pages":""},"PeriodicalIF":11.3,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43980515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Tobacco Mosaic Virus and the History of Molecular Biology. 烟草花叶病毒与分子生物学的历史。

IF 11.3 1区医学

Annual Review of Virology Pub Date : 2022-06-15 DOI: 10.1146/annurev-virology-100520-014520

A. Creager

引用次数: 6

The Ecology of Viral Emergence. 病毒出现的生态学。

IF 11.3 1区医学

Annual Review of Virology Pub Date : 2022-06-15 DOI: 10.1146/annurev-virology-100120-015057

E. Holmes

{"title":"The Ecology of Viral Emergence.","authors":"E. Holmes","doi":"10.1146/annurev-virology-100120-015057","DOIUrl":"https://doi.org/10.1146/annurev-virology-100120-015057","url":null,"abstract":"The coronavirus disease 2019 (COVID-19) pandemic has had a profound impact on human health, economic well-being, and societal function. It is essential that we use this generational experience to better understand the processes that underpin the emergence of COVID-19 and other zoonotic diseases. Herein, I review the mechanisms that determine why and how viruses emerge in new hosts, as well as the barriers to this process. I show that traditional studies of virus emergence have an inherent anthropocentric bias, with disease in humans considered the inevitable outcome of virus emergence, when in reality viruses are integral components of a global ecosystem characterized by continual host jumping with humans also transmitting their viruses to other animals. I illustrate these points using coronaviruses, including severe acute respiratory syndrome coronavirus 2, as a case study. I also outline the potential steps that can be followed to help mitigate and prevent future pandemics, with combating climate change a central component. Expected final online publication date for the Annual Review of Virology, Volume 9 is September 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":"1 1","pages":""},"PeriodicalIF":11.3,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41997129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Shifting the Immune Memory Paradigm: Trained Immunity in Viral Infections. 改变免疫记忆模式：病毒感染中的训练免疫。

IF 11.3 1区医学

Annual Review of Virology Pub Date : 2022-06-08 DOI: 10.1146/annurev-virology-091919-072546

E. Taks, S. Moorlag, M. Netea, J. van der Meer

引用次数: 7

The Case for Studying New Viruses of New Hosts. 研究新宿主的新病毒的案例。

IF 11.3 1区医学

Annual Review of Virology Pub Date : 2022-06-07 DOI: 10.1146/annurev-virology-100220-112915

M. Stenglein

引用次数: 4

Crowning Touches in Positive-Strand RNA Virus Genome Replication Complex Structure and Function. Crowning涉及正链RNA病毒基因组复制复合体的结构和功能。

IF 11.3 1区医学

Annual Review of Virology Pub Date : 2022-05-24 DOI: 10.1146/annurev-virology-092920-021307

M. Nishikiori, J. D. den Boon, Nuruddin Unchwaniwala, P. Ahlquist

{"title":"Crowning Touches in Positive-Strand RNA Virus Genome Replication Complex Structure and Function.","authors":"M. Nishikiori, J. D. den Boon, Nuruddin Unchwaniwala, P. Ahlquist","doi":"10.1146/annurev-virology-092920-021307","DOIUrl":"https://doi.org/10.1146/annurev-virology-092920-021307","url":null,"abstract":"Positive-strand RNA viruses, the largest genetic class of eukaryotic viruses, include coronaviruses and many other established and emerging pathogens. A major target for understanding and controlling these viruses is their genome replication, which occurs in virus-induced membrane vesicles that organize replication steps and protect double-stranded RNA intermediates from innate immune recognition. The structure of these complexes has been greatly illuminated by recent cryo-electron microscope tomography studies with several viruses. One key finding in diverse systems is the organization of crucial viral RNA replication factors in multimeric rings or crowns that among other functions serve as exit channels gating release of progeny genomes to the cytosol for translation and encapsidation. Emerging results suggest that these crowns serve additional important purposes in replication complex assembly, function, and interaction with downstream processes such as encapsidation. The findings provide insights into viral function and evolution and new bases for understanding, controlling, and engineering positive-strand RNA viruses. Expected final online publication date for the Annual Review of Virology, Volume 9 is September 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":" ","pages":""},"PeriodicalIF":11.3,"publicationDate":"2022-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43807803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

The Life Cycle of the Vaccinia Virus Genome. 牛痘病毒基因组的生命周期。

IF 11.3 1区医学

Annual Review of Virology Pub Date : 2022-05-18 DOI: 10.1146/annurev-virology-091919-104752

Matthew D. Greseth, P. Traktman

引用次数: 27

Understanding the Impacts of Bacteriophage Viruses: From Laboratory Evolution to Natural Ecosystems. 了解噬菌体病毒的影响：从实验室进化到自然生态系统。

IF 11.3 1区医学

Annual Review of Virology Pub Date : 2022-05-18 DOI: 10.1146/annurev-virology-091919-075914

B. Koskella, C. A. Hernandez, Rachel M. Wheatley

{"title":"Understanding the Impacts of Bacteriophage Viruses: From Laboratory Evolution to Natural Ecosystems.","authors":"B. Koskella, C. A. Hernandez, Rachel M. Wheatley","doi":"10.1146/annurev-virology-091919-075914","DOIUrl":"https://doi.org/10.1146/annurev-virology-091919-075914","url":null,"abstract":"Viruses of bacteriophages (phages) have broad effects on bacterial ecology and evolution in nature that mediate microbial interactions, shape bacterial diversity, and influence nutrient cycling and ecosystem function. The unrelenting impact of phages within the microbial realm is the result, in large part, of their ability to rapidly evolve in response to bacterial host dynamics. The knowledge gained from laboratory systems, typically using pairwise interactions between single-host and single-phage systems, has made clear that phages coevolve with their bacterial hosts rapidly, somewhat predictably, and primarily by counteradapting to host resistance. Recent advancement in metagenomics approaches, as well as a shifting focus toward natural microbial communities and host-associated microbiomes, is beginning to uncover the full picture of phage evolution and ecology within more complex settings. As these data reach their full potential, it will be critical to ask when and how insights gained from studies of phage evolution in vitro can be meaningfully applied to understanding bacteria-phage interactions in nature. In this review, we explore the myriad ways that phages shape and are themselves shaped by bacterial host populations and communities, with a particular focus on observed and predicted differences between the laboratory and complex microbial communities. Expected final online publication date for the Annual Review of Virology, Volume 9 is September 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":" ","pages":""},"PeriodicalIF":11.3,"publicationDate":"2022-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45644856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

Natural Selection, Intracellular Bottlenecks of Virus Populations, and Viral Superinfection Exclusion. 自然选择、病毒群体的细胞内瓶颈和病毒重叠感染排除。

IF 11.3 1区医学

Annual Review of Virology Pub Date : 2022-05-13 DOI: 10.1146/annurev-virology-100520-114758

Camila Perdoncini Carvalho, Ruifan Ren, Junping Han, F. Qu

{"title":"Natural Selection, Intracellular Bottlenecks of Virus Populations, and Viral Superinfection Exclusion.","authors":"Camila Perdoncini Carvalho, Ruifan Ren, Junping Han, F. Qu","doi":"10.1146/annurev-virology-100520-114758","DOIUrl":"https://doi.org/10.1146/annurev-virology-100520-114758","url":null,"abstract":"Natural selection acts on cellular organisms by ensuring the genes responsible for an advantageous phenotype consistently reap the phenotypic advantage. This is possible because reproductive cells of these organisms are almost always haploid, separating the beneficial gene from its rival allele at every generation. How natural selection acts on plus-strand RNA viruses is unclear because these viruses frequently load host cells with numerous genome copies and replicate thousands of progeny genomes in each cell. Recent studies suggest that these viruses encode the Bottleneck, Isolate, Amplify, Select (BIAS) mechanism that blocks all but a few viral genome copies from replication, thus creating the environment in which the bottleneck-escaping viral genome copies are isolated from each other, allowing natural selection to reward beneficial mutations and purge lethal errors. This BIAS mechanism also blocks the genomes of highly homologous superinfecting viruses, thus explaining cellular-level superinfection exclusion. Expected final online publication date for the Annual Review of Virology, Volume 9 is September 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":48761,"journal":{"name":"Annual Review of Virology","volume":" ","pages":""},"PeriodicalIF":11.3,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48854584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7