Journal of Evidence-Based Dental Practice最新文献

{"title":"THE TYPE OF ORTHODONTIC LIGATURE DOES NOT INFLUENCE PERIODONTAL HEALTH TO A CLINICALLY RELEVANT DEGREE","authors":"Carlos Flores-Mir (REVIEWER)","doi":"10.1016/j.jebdp.2025.102091","DOIUrl":"10.1016/j.jebdp.2025.102091","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Hussain U et al. Influence of elastomeric and steel ligatures on periodontal health during fixed appliance orthodontic treatment: a systematic review and meta-analysis. Prog Orthod 2024; 25: 24. <span><span>doi.org/10.1186/s4-510-024-00520-8</span><svg><path></path></svg></span>.</div></div><div><h3>Source of Funding</h3><div><em>None</em>.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with meta-analysis.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102091"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143550593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LONG-TERM ORAL APPLIANCE THERAPY FOR OBSTRUCTIVE SLEEP APNEA MAY LEAD TO MORE CONSISTENT DENTOALVEOLAR THAN SKELETAL CHANGES","authors":"JARED LAYTON (Reviewers),&nbsp;KYLE HASTINGS,&nbsp;THIKRIAT AL-JEWAIR","doi":"10.1016/j.jebdp.2025.102130","DOIUrl":"10.1016/j.jebdp.2025.102130","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Chen Y, Alhozgi AI, Almeida FR. Dentoskeletal changes of long-term oral appliance treatment in patients with obstructive sleep apnea: A systematic review and meta-analysis. J Prosthodont 2024 (In eng). DOI: 10.1111/jopr.13946.</div></div><div><h3>Source of Funding</h3><div>No financial support was obtained for this study.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review and Meta-Analysis</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102130"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PERIODONTITIS AS A RISK FACTOR FOR DEMENTIA: A SYSTEMATIC REVIEW AND META-ANALYSIS","authors":"DONG-HEE KIM,&nbsp;GYEONG-SOON HAN","doi":"10.1016/j.jebdp.2025.102094","DOIUrl":"10.1016/j.jebdp.2025.102094","url":null,"abstract":"<div><h3>Introduction</h3><div>The association between periodontitis and dementia remains controversial. Therefore, we analyzed this association focusing on the severity of periodontitis and type of dementia.</div></div><div><h3>Methods</h3><div>We searched the PubMed, Embase, Web of Science, and gray literature (OpenGrey, ProQuest) databases from inception to June 30, 2021, and pooled the data for meta-analysis. Fixed- or random-effects models were employed to calculate odds ratios (ORs), hazard ratios (HRs), and 95% confidence intervals (CIs) to evaluate the strength of the associations between periodontitis and dementia.</div></div><div><h3>Results</h3><div>Thirteen case-control and 11 cohort studies were selected. The analysis of entire studies indicated an association between periodontitis and dementia, with an OR of 2.26 (95% CI, 1.65−3.09; <em>P</em> &lt; .0001) and HR of 1.15 (95% CI, 1.04−1.27; <em>P</em> = .0006). According to periodontitis severity, the risk of dementia was significantly associated with severe periodontitis (OR = 2.85; 95% CI, 2.16−3.74; <em>P</em> = .038), but not with less-than-moderate periodontitis (OR = 0.94; 95% CI, 0.64−1.40; <em>P</em> = .66). In particular, patients with severe periodontitis had a 6.87-fold higher risk of Alzheimer's dementia (OR = 6.87; 95% CI, 2.55−18.54; <em>P</em> = .04) and 2.92-fold higher risk of cognitive impairment (OR = 2.92, 95% CI, 2.15−3.96; <em>P</em> = .36).</div></div><div><h3>Conclusions</h3><div>We found a strong association between periodontitis and dementia, with severe periodontitis identified as a potential risk factor for Alzheimer's dementia. Therefore, timely management of periodontitis to prevent its progression may help prevent dementia.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102094"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143429091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TRANSLATIONAL APPLICATION OF COLD ATMOSPHERIC PLASMA IN PERIODONTOLOGY AND IMPLANTOLOGY: WHERE ARE WE? A SYSTEMATIC REVIEW OF IN VIVO STUDIES IN HUMAN AND ANIMAL MODELS","authors":"GIORGIA STORNELLI ,&nbsp;GIULIA PETRUCCI ,&nbsp;VITO CARLO ALBERTO CAPONIO ,&nbsp;ELOISA SARDELLA ,&nbsp;GIUSEPPE BALICE ,&nbsp;BEATRICE FEMMINELLA ,&nbsp;MICHELE PAOLANTONIO ,&nbsp;ILARIA CELA ,&nbsp;TIRTHA RAJ ACHARYA ,&nbsp;NAYANSI JHA ,&nbsp;NAGENDRA KUMAR KAUSHIK ,&nbsp;EUN HA CHOI ,&nbsp;VALENTINA PUCA ,&nbsp;ROSSELLA GRANDE ,&nbsp;VITTORIA PERROTTI","doi":"10.1016/j.jebdp.2025.102096","DOIUrl":"10.1016/j.jebdp.2025.102096","url":null,"abstract":"<div><h3>Aim</h3><div>The utilization of cold atmospheric plasma (CAP) in dentistry presents a promising avenue for novel therapeutic interventions. This systematic review of in vivo studies aimed at summarizing the existing evidence regarding the efficacy of CAP as a treatment for biofilms associated with periodontitis and peri-implantitis. The objective was to advance the definition and standardization of protocols and facilitate the integration of CAP treatment as a chair-side practice.</div></div><div><h3>Materials and Methods</h3><div>This review was registered in PROSPERO database (CRD42023404757), and a comprehensive search was conducted following PRISMA guidelines and using PubMed, Scopus, Web of Science, and Embase databases.</div></div><div><h3>Results</h3><div>In total, 9 in vivo studies were included, 1 on humans and 8 on animal models. A notable reduction in residual bacteria when CAP was combined with conventional therapies in both periodontitis and peri-implantitis models was observed. Biochemical and histological assays demonstrated a decrease in inflammatory cytokines within crevicular fluid and oral tissues.</div></div><div><h3>Conclusions</h3><div>Current evidence suggests that CAP shows promise for periodontitis and peri-implantitis treatment, but further clinical trials with larger cohorts and standardized protocols are needed to confirm its efficacy and safety.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102096"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143422713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Statement of Purpose/Levels of Evidence","authors":"","doi":"10.1016/S1532-3382(25)00064-8","DOIUrl":"10.1016/S1532-3382(25)00064-8","url":null,"abstract":"","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102149"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANTIPLAQUE AND ANTIGINGIVITIS EFFECTS OF A NOVEL ORAL CARE REGIMEN FEATURING STANNOUS FLUORIDE TOOTHPASTE, A UNIQUE TOOTHBRUSH, AND CETYLPYRIDINIUM CHLORIDE MOUTHWASH: A RANDOMIZED CLINICAL TRIAL","authors":"FARID AYAD ,&nbsp;MAHA HETATA ,&nbsp;RABAB AHMED ,&nbsp;TAKAHIDE OKAI ,&nbsp;GOKUL GOVINDARAJU ,&nbsp;LUIS R. MATEO ,&nbsp;MARIA RYAN ,&nbsp;BAYARDO GARCÍA-GODOY","doi":"10.1016/j.jebdp.2025.102123","DOIUrl":"10.1016/j.jebdp.2025.102123","url":null,"abstract":"<div><h3>Background</h3><div>Antibacterial ingredients for oral care products are typically measured through single product forms. This study assessed the overall health outcome of using multiple forms: a stabilized stannous fluoride toothpaste, an enhanced cetylpyridinium chloride mouthwash and a unique toothbrush to deliver antibacterial performance.</div></div><div><h3>Methods</h3><div>A 12-week, single-center, phase III, masked, 2-arm, parallel-group, randomized controlled trial was conducted to assess the reduction of established dental plaque and gingivitis with a novel antibacterial oral regimen comprised of 0.454% stannous fluoride toothpaste stabilized with nitrate and phosphates, 0.075% cetylpyridinium chloride and 0.28% zinc lactate mouthwash, and rapid foaming manual toothbrush compared to a nonantibacterial commercially available regimen of toothpaste containing 0.76% sodium monofluorophosphate, no mouthwash, and commercially available manual toothbrush to represent standard toothbrushing practices.</div></div><div><h3>Results</h3><div>Adherence to this novel oral care regimen provided significant reduction in plaque and gingivitis compared to the control starting at 1 week (<em>P</em> &lt; .01) and continuing over 12 weeks (<em>P</em> &lt; .001) across all plaque and gingival score indices. At week 1, participants in the Antibacterial Regimen Group showed 15 times more plaque reduction than control (<em>P</em> &lt; .001). After 3 weeks of regimen adherence, 100% of Antibacterial Regimen participants had improved gingival index scores compared to baseline.</div></div><div><h3>Conclusions</h3><div>Within the limitations of the study, the results showed statistically significantly reduced gingival inflammation and improved plaque control from 1 week continuing through 12 weeks of adherence to this novel oral care regimen compared to standard toothbrushing practices.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102123"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143578851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PROPHYLACTIC ANTIBIOTIC USE IN LOWER THIRD MOLAR SURGERY MAY REDUCE DRY SOCKET AND INFECTIONS, BUT EVIDENCE REMAINS WEAK","authors":"OMER WALEED MAJID (Reviewer)","doi":"10.1016/j.jebdp.2025.102128","DOIUrl":"10.1016/j.jebdp.2025.102128","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Camps-Font O, Sábado-Bundó H, Toledano-Serrabona J, Valmaseda-de-la-Rosa N, Figueiredo R, Valmaseda-Castellón E. Antibiotic prophylaxis in the prevention of dry socket and surgical site infection after lower third molar extraction: a network meta-analysis. Int J Oral Maxillofac Surg. 2024;53(1):57-67.</div></div><div><h3>Source of Funding</h3><div>None declared.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with network meta-analysis.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102128"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143682657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI-AIDED VOLUMETRIC ROOT RESORPTION ASSESSMENT FOLLOWING PERSONALIZED FORCES IN ORTHODONTICS: PRELIMINARY RESULTS OF A RANDOMIZED CLINICAL TRIAL","authors":"NAVARRO-FRAILE ESTRELLA ,&nbsp;DEHESA-SANTOS ALEXANDRA ,&nbsp;CHEN YUN ,&nbsp;JUAN CARLOS PALMA-FERNÁNDEZ ,&nbsp;IGLESIAS-LINARES ALEJANDRO","doi":"10.1016/j.jebdp.2025.102095","DOIUrl":"10.1016/j.jebdp.2025.102095","url":null,"abstract":"<div><h3>Introduction</h3><div>External apical root resorption (EARR) is an undesirable loss of hard tissues of the tooth root frequently affecting to the maxillary incisors. The magnitude of orthodontic forces is a major treatment-related factor associated with EARR occurrence in orthodontics. The primary aim of the present randomized clinical trial was (i) to quantify the impact of a sequence of personalized force archwires on EARR compared to the conventional standard of care and (ii) compare the 3D-quantification of EARR using two quantification methods (manual or automated AI-aided segmentation).</div></div><div><h3>Material and Methods</h3><div>A superiority two arms-parallel-randomized clinical trial (RCT) was conducted to quantify the EARR of two regime forces [CONSORT-guidelines]. A total of 18/43 patients were randomly assigned [block-size: 4] to C<em>ontrol Group</em> [Ni-Ti archwires sequence] or E<em>xperimental Group</em> [selective <em>individualized</em> force archwires]. After 142 days sectorial CBCT were obtained; upper incisors were segmented manually and with AI and the volume/length of root quantified. Method error/descriptive statistics (mean; SD; range) and Student <em>t</em>-test were used to assess the differences between groups (<em>Post hoc</em> adjustment for confounders [95% CI; <em>P</em> &lt; .05]).</div></div><div><h3>Results</h3><div>The total root volume loss detected by AI was 2.44 ± 6.59 mm³ / 2.42 ± 4.75 mm³ (<em>P</em> &gt; .05) and the mean root length loss was 0.20± 0.23mm/0.42 ± 0.43 mm (<em>P</em> = .045) for control/test group, respectively. Despite length loss showed similar changes when it was quantified with both methods, manual and automatic segmentations (<em>P</em> &gt; .05), differences are observed at volume loss. The results demonstrated greater volume loss detection with manual segmentation than with AI-aided segmentation at the global level, volume by thirds, and 4 mm from the apex. However, as we approached apically, the differences equalized and even diminished, resulting in a greater loss with automatic segmentation 1 mm from the apex in the EG (<em>P</em> = .011).</div></div><div><h3>Conclusions</h3><div>A non direct-force-dependent effect over EARR (6 months) was observed. Individualized force induces slightly higher root resorption at the apical third at 1-2 mm.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102095"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143464297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EFFICACY OF A REMINERALIZATION AGENT CONTAINING AMMONIUM FLUORIDE SOLUTION AND NANO SOL CALCIUM FLUORIDE FOR TREATMENT OF INITIAL BUCCAL CARIES LESIONS: A SPLIT-MOUTH RANDOMIZED CONTROLLED CLINICAL TRIAL","authors":"BURCU GÖZETİCİ-ÇİL DDS, PhD ,&nbsp;SAFİYE SELİN KÖYMEN DDS, PhD ,&nbsp;AYŞE TAŞ DDS, PhD ,&nbsp;HİLAL YILANCI DDS, PhD ,&nbsp;MUTLU ÖZCAN DDS, DMD, PhD","doi":"10.1016/j.jebdp.2025.102093","DOIUrl":"10.1016/j.jebdp.2025.102093","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of the study was to investigate the efficacy of ammonium fluoride solution (AFS) combined with nano sol calcium fluoride (nano-CaF₂) for the treatment of active buccal white spot lesions (WSLs) in permanent dentition.</div></div><div><h3>Materials and Methods</h3><div>Participants with at least 2 WSLs in different quadrants were included in the splitmouth randomized clinical trial. The WSLs meeting the inclusion criteria (n = 60) were randomly assigned into test and control groups. The WSLs in test group (n = 30) received AFS (25,000 ppmF^-) and nano-CaF₂ (41,400 ppmF^-) as a 2-step treatment (Experimental product, Ivoclar Vivadent AG, Schaan, Liechtenstein), while the WSLs in control group (n = 30) received 1-step ammonium fluoride varnish (AFV, 7700 ppmF^-, Fluor Protector S, Ivoclar Vivadent AG) treatment. The WSLs were quantitatively assessed using QLF (QrayCam, AIOBIO, Seoul, Republic of Korea) and qualitatively assessed using International Caries Detection and Assessment System (ICDAS-II) and Nyvad criteria at baseline, 1, 6 and 12-months follow-ups. The difference in QLF parameters within each group (Friedman test) and between groups (Wilcoxon test) was analyzed. Binary logistic regression model was used to compare the odds of the WSLs showed regression between the groups based on qualitative assessment.</div></div><div><h3>Results</h3><div>Overall, 56 WSLs in 21 participants (ages ranged from 14 to 40 years) could be evaluated. Quantitatively, mineral loss (ΔF average and ΔF max), lesion size (WS area) and volume (ΔQ) decreased significantly in test group (<em>P</em> = .001) at 6 and 12 months compared to baseline, whereas no significant difference was found in control group (<em>P</em> &gt; .05). Intergroup comparison showed greater reduction in ΔF average and ΔF max values in the test group compared to control group at 6-month`s follow-up (<em>P</em> = .05). Qualitatively assessed regression rate was higher in test group compared to control group at 6 and 12-months (<em>P</em> &lt; .05).</div></div><div><h3>Conclusion</h3><div>Caries preventive efficacy of AFS + nano-CF2 was found to be superior to AFV based on both quantitative and qualitative assessment in high caries risk adolescents and young adults.</div></div><div><h3>Clinical Relevance</h3><div>Two-step treatment with high level of AFS and nano sol CaF₂ might be a better option compared to 1-step AFV treatment for the management of WSLs.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102093"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143550597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IS THERE A CORRELATION BETWEEN OBJECTIVE AND SUBJECTIVE METHODS TO ASSESS DENTAL ANXIETY? A SYSTEMATIC REVIEW AND META-ANALYSIS","authors":"CAMILA SILVA DE AMORIM MsC ,&nbsp;LARISSA SOARES LIMA DA SILVA MsC ,&nbsp;GUIDO ARTEMIO MARAÑÓN-VÁSQUEZ PhD ,&nbsp;MARCELA BARAÚNA MAGNO PhD ,&nbsp;ANDRÉA VAZ BRAGA PINTOR PhD ,&nbsp;PEDRO PAULO PIRES PhD ,&nbsp;LUCIANNE COPLE MAIA PhD ,&nbsp;MATHEUS MELO PITHON PhD","doi":"10.1016/j.jebdp.2025.102092","DOIUrl":"10.1016/j.jebdp.2025.102092","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the evidence about the correlation between objective and subjective methods for evaluating dental anxiety.</div></div><div><h3>Methods</h3><div>Eligibility criteria were defined as follows: Patients (P): individuals in the dental care context; Index test (I): subjective methods; Reference test (R): objective methods; Outcome (O): correlation between methods to dental anxiety evaluation. Searches were conducted in 7 databases and grey literature up to November 2023, without language or date restrictions. The QUADAS-2 tool was employed to evaluate Risk of bias. A random-effects meta-analysis was performed to calculate pooled correlation coefficients between methods on the basis of the objective method analyzed. The GRADE approach was utilized to assess evidence certainty.</div></div><div><h3>Results</h3><div>A total of 29 studies, with 1891 participants aged 3 to 82 years, were included, with 22 studies participating in the meta-analysis. The Risk of bias was mostly “unclear” due to inadequate methodology detail. Weak correlations were observed between subjective methods and heart rate (r 0.15 [0.08, 0.21], <em>P</em> &lt; .001, I² = 56%) and alpha-amylase (r 0.25 [0.11, 0.38], <em>P</em> &lt; .001, I² = 43%. Subjective methods showed a moderate correlation with cortisol analysis (r 0.40 [0.33, 0.47] <em>P</em> &lt; .001, I² = 72%). No other objective method displayed a significant correlation with subjective methods. The certainty of evidence was very low.</div></div><div><h3>Conclusion</h3><div>The findings can suggest a correlation between the following subjective and objective methods: ACDAS, DAS, MCDAS, MDAS and Cortisol; CFSS-DS, DAS, MCDAS, MDAS and Alpha-amylase; and DAS, DAS-R, MDAS, S-DAI, Venham Picture Anxiety, Venham Picture Test and Heart rate. Nonetheless, these results lack conclusiveness due to their very low certainty of evidence.</div></div><div><h3>Registration</h3><div>PROSPERO database registration number CRD42022298589.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102092"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143534829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}