Journal of Evidence-Based Dental Practice最新文献

{"title":"Information for Readers","authors":"","doi":"10.1016/S1532-3382(25)00065-X","DOIUrl":"10.1016/S1532-3382(25)00065-X","url":null,"abstract":"","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102150"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TOPICAL FLUORIDES MAY PREVENT RADIATION CARIES IN ADULTS UNDERGOING HEAD AND NECK RADIOTHERAPY","authors":"ANA GUTIERREZ GOSSWEILER MSD (REVIEWERS),&nbsp;E. Angeles Martinez Mier PhD","doi":"10.1016/j.jebdp.2024.102050","DOIUrl":"10.1016/j.jebdp.2024.102050","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Deepali Agarwal, Bharathi Purohit, Priyanka Ravi, Harsh Priya, Vijay Kumar. Effectiveness of Topical Fluorides in Prevention of Radiation Caries in Adults: A Systematic Review and Meta-Analysis. Oral Oncology. 2022.</div></div><div><h3>Source of Funding</h3><div>Information not available.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with meta-analysis of data.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102050"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EFFICACY AND SAFETY OF LIDOCAINE WITH CLONIDINE FOR MAXILLARY INFILTRATION ANESTHESIA IN PATIENTS WITH DIABETES MELLITUS TYPE 2: DOUBLE-BLIND, RANDOMIZED CLINICAL TRIAL","authors":"MARIJA S. MILIC ,&nbsp;BOZIDAR BRKOVIC ,&nbsp;MILAN VUCETIC ,&nbsp;VLADIMIR S. TODOROVIC ,&nbsp;DRAGICA STOJIC","doi":"10.1016/j.jebdp.2025.102097","DOIUrl":"10.1016/j.jebdp.2025.102097","url":null,"abstract":"<div><h3>Objectives</h3><div>This clinical trial aimed to evaluate and compare parameters of intraoral soft tissue anesthesia and cardiovascular function, and prevalence of local side effects in patients with and without diabetes mellitus type 2 (DMT2), after maxillary infiltration anesthesia obtained with 2% lidocaine with either clonidine (15mcg/ml) or epinephrine (1:100.000).</div></div><div><h3>Methods</h3><div>Sixty-three DMT2 and 52 nondiabetic (H) patients scheduled for tooth extraction were randomly assigned to receive one of the local anesthetic solutions for maxillary infiltration anesthesia: 2 mL of lidocaine with clonidine (LC) or 2 mL of lidocaine with epinephrine (LE). Parameters of soft tissue anesthesia (onset, duration and width of anesthetic field) were evaluated by <em>pinprick</em> test. Systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) were monitored with patient monitor, before and until 30 minutes after anesthesia application. Presence of postoperative hyperalgesia and paresthesia during 7 postoperative days was tested with ethylene-chloride spray and monofilaments set for quantitative sensory testing, respectively. Requests for rescue analgesic were recorded for 24 hours after tooth extraction.</div></div><div><h3>Results</h3><div>Onset of maxillary infiltration anesthesia was significantly shorter in DMT2 vs. H groups (<em>P</em> &lt; .05), regardless of local anesthetic solution used. Duration of anesthesia was 59% longer in DMT2-LE vs. H-LE (<em>P</em> &lt; .05), and 28% longer in DMT2-LC vs. H-LC groups (<em>P</em> &lt; .05). Maxillary infiltration anesthesia lasted 37,9% longer in DMT2-LE vs. DMT2-LC (182.09 ± 57.86 min vs. 139.48 ± 21.86 min) (<em>P</em> &lt; .05). Width of anesthetic field was significantly increased in diabetic vs. nondiabetic participants (<em>P</em> &lt; .05), as well as in DMT2-LE vs. DMT2-LC (35.19 ± 1.67mm vs. 27.07 ± 1.06 mm) (<em>P</em> &lt; .05). SBP was significantly decreased within DM-LC and H-LC groups from 15th to 30th minute, in comparison with baseline values. Significant increase in HR was observed from 5th to 30th minute in diabetic and nondiabetic patients who received LE, compared to baseline values. Postoperative paresthesia was significantly more present in DMT2-LE vs. DMT2-LC (<em>P</em> &lt; .05), while it was not observed in nondiabetic patients.</div></div><div><h3>Conclusions</h3><div>Shorter onset and prolonged duration of maxillary infiltration anesthesia are present in DMT2 setting. Clonidine appears to be a safe alternative to epinephrine for intraoral anesthesia in DMT2, with respect to anesthetic efficacy, cardiovascular safety and prevalence of local side effects.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102097"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143429092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI-DRIVEN NASOALVEOLAR MOLDING DESIGN FOR CLEFT PATIENTS MAY BE A PROMISING BUT EVOLVING APPROACH","authors":"AHMAD AL-KANDARI (Reviewers),&nbsp;PEDRO ANDRADE,&nbsp;THIKRIAT AL-JEWAIR","doi":"10.1016/j.jebdp.2025.102131","DOIUrl":"10.1016/j.jebdp.2025.102131","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Artificial intelligence-driven automation of nasoalveolar molding device planning: A systematic review. Alqutaibi AY, Hamadallah HH, Alassaf MS, Othman AA, Qazali AA, Alghauli MA. J Prosthet Dent. 2024 Oct 4:S0022-3913(24)00637-1. <span><span>doi: 10.1016/j.prosdent.2024.09.011</span><svg><path></path></svg></span>. Epub ahead of print. PMID: 39368883.</div></div><div><h3>Source of Funding</h3><div>This research did not receive any grant from any funding agency in the public, commercial, or not-for- profit sectors. The authors declared that they had no financial interests or personal relationships that could influence the work reported in the study.</div></div><div><h3>Type of Study/Design</h3><div>Systematic Review.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102131"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THREE YEARS CLINICAL ASSESSMENT OF LOW CONCENTRATION DIMETHYL SULFOXIDE PRIMER IN NON CARIOUS CERVICAL LESIONS: A RANDOMIZED CONTROLLED TRIAL","authors":"OMAR ABDELAZIZ ISMAIL DDS, MSc ,&nbsp;OLFAT ELSAYED HASSANEIN DDS, Ph.D. ,&nbsp;RANDA HAFEZ DDS, Ph.D. ,&nbsp;MAI MAMDOUH DDS, Ph.D. ,&nbsp;OMAR SHAALAN DDS, Ph.D. ,&nbsp;ARZU TEZVERGIL-MUTLUAY DDS, Ph.D. FADM","doi":"10.1016/j.jebdp.2025.102124","DOIUrl":"10.1016/j.jebdp.2025.102124","url":null,"abstract":"<div><h3>Objectives</h3><div>to evaluate the clinical effectiveness of 1% dimethyl-sulfoxide (DMSO/H₂O) dentin pretreatment on the clinical performance of 2-step etch-rinse adhesive after 36-months of a follow-up.</div></div><div><h3>Methods</h3><div>Twenty-nine patients with 82 non carious-cervical lesions NCCLs were eligible for the study. NCCLs were randomly distributed into 2 equal groups. Both groups were acid etched then bonded with (Single-bond2, 3M-ESPE) and restored with a nanohybrid composite (Z350XT, 3M-ESPE) under rubber-dam isolation. Only for the intervention group 1% DMSO/H₂O was applied for 60s then blot dried after etching and before bonding. The restorations were evaluated at baseline, 12-, 24-, and 36-months using FDI criteria for evaluation of the restoration. For the statistical analysis, intergroup comparison between interventions was performed using Chi-Square-test (<em>P</em> ≤ .05), intragroup comparison within each intervention was performed using the Cochran's Q-test (<em>P</em> ≤ .0083).</div></div><div><h3>Results</h3><div>In the current study, intergroup comparison between both groups at baseline and after 12, 24 and 36 months showed no statistically significant differences for all tested outcomes (<em>P</em> &gt; .05), except for marginal discoloration at 36 months, where there was statistically significant difference (<em>P</em> &lt; .05) favoring DSMO. Intragroup comparison within control revealed statistically significant deterioration through time (<em>P</em> &lt; .001) for all tested parameters, also within DSMO there was statistically significant change through time (<em>P</em> &lt; .0083).</div></div><div><h3>Conclusion</h3><div>The clinical performance of a 2-step etch-rinse adhesive in combination with 1% DMSO pretreatment was better than the control without pretreatment. Longer follow-up and higher concentrations of DMSO pretreatment should be evaluated in the future.</div></div><div><h3>Clinical Significance</h3><div>Several laboratory studies showed that DMSO pretreatment improves the hybrid layer quality and integrity. However, this clinical trial gave the proof of the clinical effectiveness of this protocol after 36-months follow-up.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102124"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143682656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EFFICACY OF STEM CELLS IN ENDODONTIC REGENERATION: A SYSTEMATIC REVIEW","authors":"NAUSHEEN AGA MClinDent ,&nbsp;SCOTT McGregor MSc ,&nbsp;SARAH JONES PhD ,&nbsp;IAN ELLIS ,&nbsp;MARCO TATULLO PhD ,&nbsp;MUNA EISA MOHAMED HASSAN PhD ,&nbsp;MOHAMMAD ISLAM PhD","doi":"10.1016/j.jebdp.2025.102125","DOIUrl":"10.1016/j.jebdp.2025.102125","url":null,"abstract":"<div><h3>Introduction</h3><div>Regenerative endodontic procedures (REPs) aim to regenerate structural and functional integrity of necrosed or infected dental pulp, while promoting root development and closure. Conventional treatment methods often fail to regenerate dental pulp tissues effectively. This systematic review investigates the efficacy of stem cell therapy in REPs.</div></div><div><h3>Methodology</h3><div>An electronic search was conducted on the following research databases and registers: PubMed (includes MEDLINE and PubMed Central), Scopus, Cochrane Central Register of Controlled Trials (CENTRAL), Google Scholar, and ClinicalTrials.gov. The study was registered in PROSPERO and PRISMA guidelines were followed to report the review. 19 original studies comprising 1 randomized clinical trial and 18 animal studies were included after applying inclusion and exclusion criteria. The studies evaluated different types of endodontic procedures, including pulp capping, pulpotomy, pulpectomy, and furcation repair, using various types of mesenchymal stem cells, such as dental pulp stem cells, bone marrow-derived stem cells and umbilical cord mesenchymal stem cells (UCMSCs). The outcomes assessed in the studies included pulpal regeneration, resolution of periapical radiolucency, and restoration of tooth vitality. The Systematic Review Center for Laboratory and Animal Experimentation (SYRCLE) and Risk of Bias 2.0 was used for assessing the risk of bias in animal studies and randomized trials, respectively.</div></div><div><h3>Results</h3><div>The findings indicate that stem cell therapy holds promise for inducing dental pulp regeneration. However, synthesizing the overall efficacy of stem cell therapy compared to conventional methods remains challenging due to variations in methodologies and outcome measures used in animal studies. Despite these inconsistencies, most animal studies reported positive results for pulpal regeneration, regardless of the stem cell type, scaffold type or animal model used. Notably, a clinical trial utilizing umbilical cord mesenchymal stem cells (UCMSCs) combined with platelet-poor plasma demonstrated favorable outcomes in dental pulp revascularization and reperfusion.</div></div><div><h3>Conclusion</h3><div>The long-term safety and clinical efficacy of stem cell therapy in regenerative endodontic procedures (REPs) require validation through randomized clinical trials before widespread clinical adoption.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102125"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LIMITED EVIDENCE SUGGESTS THAT CHATGPT MAY HAVE ACCURATE RESPONSES IN MEDICAL AND DENTAL RESEARCH","authors":"IMAN ABD-ELWAHAB RADI (REVIEWERS),&nbsp;MARIAM TAHER ABDELFATTAH ABOUMOSALLAM","doi":"10.1016/j.jebdp.2025.102090","DOIUrl":"10.1016/j.jebdp.2025.102090","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Bagde H, Dhopte A, Alam MK, Basri R. A systematic review and meta-analysis on ChatGPT and its utilization in medical and dental research. Heliyon. 2023 Dec 1;9(12).</div></div><div><h3>Source of Funding</h3><div>Information not available.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with meta-analysis of data (SRMA).</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102090"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143550592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMPARING THE EFFICACY OF OSSEODENSIFICATION OVER CONVENTIONAL DRILLING TECHNIQUE ON IMPLANT STABILITY AND BONE DENSITY IN LOW BONE DENSITY SITES: A SYSTEMATIC REVIEW AND META-ANALYSIS","authors":"SHRADDHA SHILPI ,&nbsp;MONIKA BANSAL ,&nbsp;MAHESH KHAIRNAR ,&nbsp;GOKILA VANI SU ,&nbsp;ZAINAB AKRAM ,&nbsp;RASHIKA M ,&nbsp;SAKSHI AGARWAL","doi":"10.1016/j.jebdp.2025.102132","DOIUrl":"10.1016/j.jebdp.2025.102132","url":null,"abstract":"<div><h3>Purpose of the research</h3><div>To assess the efficacy of osseodensification (OD) over conventional drilling technique (CD) on implant stability and bone density in low bone density sites.</div></div><div><h3>Materials and methods</h3><div>An electronic and manual search were conducted to analyze the effect of OD over CD technique on implant stability and bone density in human-based randomized controlled trials (RCTs) and nonrandomized controlled trials (NRCTs). The risk of bias was assessed using (RoB 2.0) and (ROBINS-I) tools for RCTs and NRCTs respectively. The meta-analysis was applied with RevMan 5.4, using the random-fixed effects model. Heterogeneity was assessed by a Q test and quantified with I² statistics.</div></div><div><h3>Results</h3><div>Our literature search identified 1454 publications, of which only 6 met all the inclusion criteria. The meta-analysis of the included studies showed that the implant stability quotient (ISQ) was greater in OD than in the CD group without being statistically significant both immediately and at the follow-up period after implant placement, with a standardized mean difference of 2.13 [95%CI = −0.08, 4.35] with <em>P</em> = .06 and 1.81 [95%CI = −0.41, 4.03] with <em>P</em> = .11 respectively. The difference in bone density in the OD compared to the CD group was statistically significant, immediately after implant placement with a standardized mean difference of 2.14 [95%CI = 0.68, 3.59] with <em>P</em> = .004 and nonsignificant at 3 to 7 months with a standardized mean difference of 1.54 [95%CI = −0.34, 3.43] with <em>P</em> = .11.</div></div><div><h3>Conclusion</h3><div>The findings of the present review and meta-analysis show that dental implants placed using the OD technique reveal greater implant stability and improved bone density in areas with low bone density compared to the CD technique. However, more clinical studies are needed to validate the findings.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102132"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Information for Authors","authors":"","doi":"10.1016/S1532-3382(25)00066-1","DOIUrl":"10.1016/S1532-3382(25)00066-1","url":null,"abstract":"","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102151"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CORRIGENDUM TO “EFFICACY AND SAFETY OF A DEXAMETHASONE-BASED MOUTHWASH TO PREVENT CHEMOTHERAPY-INDUCED STOMATITIS IN WOMEN WITH BREAST CANCER: A MULTICENTRE, OPEN-LABEL, RANDOMISED PHASE 2 STUDY” [J EVID BASED DENT PRACT. 2023 SEP;23(3):101896]","authors":"SAYAKA KUBA ,&nbsp;SHIGETO MAEDA ,&nbsp;KENICHIRO SHIBATA ,&nbsp;SAKIKO SOUTOME ,&nbsp;KOSHO YAMANOUCHI ,&nbsp;MEGUMI MATSUMOTO ,&nbsp;AYA TANAKA ,&nbsp;MICHI MORITA ,&nbsp;TOSHIKO HATACHI ,&nbsp;RYOTA OTSUBO ,&nbsp;HIROSHI YANO ,&nbsp;YUMIKO KAWASHITA ,&nbsp;SHUNTARO SATO ,&nbsp;HIDEKI TANIGUCHI ,&nbsp;KENGO KANETAKA ,&nbsp;MASAHIRO UMEDA ,&nbsp;TAKESHI NAGAYASU ,&nbsp;SUSUMU EGUCHI","doi":"10.1016/j.jebdp.2024.102054","DOIUrl":"10.1016/j.jebdp.2024.102054","url":null,"abstract":"","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 2","pages":"Article 102054"},"PeriodicalIF":4.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}