ARCHANA PRADHAN (REVIEWERS), ARASH GHANBARZADEGAN, THILINI N. JAYASINGHE
{"title":"ORAL CARE AND DENTAL INTERVENTIONS SHOW MIXED AND UNCLEAR EFFECTS ON COGNITIVE FUNCTION","authors":"ARCHANA PRADHAN (REVIEWERS), ARASH GHANBARZADEGAN, THILINI N. JAYASINGHE","doi":"10.1016/j.jebdp.2024.102039","DOIUrl":"10.1016/j.jebdp.2024.102039","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>DO ORAL CARE AND REHABILITATION IMPROVE COGNITIVE FUNCTION?</div><div>A SYSTEMATIC REVIEW OF CLINICAL STUDIES</div><div>Inamochi Y, Ogino Y, Harada K, Fueki K, Ayukawa Y, Nishimura M, Maekawa K, Kang Y, Hirai T, Kuboki T. DO ORAL CARE AND REHABILITATION IMPROVE COGNITIVE FUNCTION? A SYSTEMATIC REVIEW OF CLINICAL STUDIES. J Evid Based Dent Pract. 2024 Mar;24(1):101948. <span><span>10.1016/j.jebdp.2023.101948</span><svg><path></path></svg></span>. Epub 2023 Oct 19. PMID: <span><span>38448117</span><svg><path></path></svg></span>.</div></div><div><h3>SOURCE OF FUNDING</h3><div>None.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"24 4","pages":"Article 102039"},"PeriodicalIF":4.1,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142553480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HSIN HSU (REVIEWERS), JOHNSON HSIN-CHUNG CHENG, CHIN-WEI WANG
{"title":"HYALURONIC ACID INJECTION MAY BE EFFECTIVE FOR RECONSTRUCTION OF MILD TO MODERATE LOSS OF INTERDENTAL PAPILLA IN ADULT PATIENTS IN THE SHORT TERM","authors":"HSIN HSU (REVIEWERS), JOHNSON HSIN-CHUNG CHENG, CHIN-WEI WANG","doi":"10.1016/j.jebdp.2024.102044","DOIUrl":"10.1016/j.jebdp.2024.102044","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>The use of hyaluronic acid injection for treatment of black triangle and reconstruction of lost interdental papilla in anterior teeth: a systematic review.</div><div>ACTA ODONTOLOGICA SCANDINAVICA 2024; VOL. 83: 371-391. DOI: <span><span>https://doi.org/10.2340/aos.v83.40864</span><svg><path></path></svg></span>.</div></div><div><h3>Source of funding</h3><div>The author did not report any financial support for this systematic review.</div></div><div><h3>Type of study/design</h3><div>Systematic review.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"24 4","pages":"Article 102044"},"PeriodicalIF":4.1,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CAD/CAM-FABRICATED RPD FRAMEWORKS SHOW LOWER FIT ACCURACY COMPARED TO CONVENTIONAL CASTING, WITH INDIRECT 3D PRINTING OFFERING COMPARABLE RESULTS","authors":"CHING YEE CONSTANCE LAW (REVIEWER)","doi":"10.1016/j.jebdp.2024.102043","DOIUrl":"10.1016/j.jebdp.2024.102043","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div><em>Accuracy of removable partial denture metal frameworks fabricated by computer-aided design/computer-aided manufacturing method: A systematic review and meta-analysis</em>. Mai HY, Mai HN, Kim HJ, Lee J, Lee DH. J Evid-Base Dent Pract. 2022 Sep 1;22(3):101681.</div></div><div><h3>Source of Funding</h3><div>Government: Korean Medical Device Development Fund grant funded by the Korea government (the Ministry of Science and ICT, the Ministry of Trade, Industry and Energy, the Ministry of Health & Welfare, Republic of Korea, the Ministry of Food and Drug Safety (202011A02).</div><div>Bio & Medical Technology Development Program of the National Research Foundation (NRF) funded by the Korean government (MSIT) (2020R1I1A1A01062967).</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with meta-analysis of data.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"24 4","pages":"Article 102043"},"PeriodicalIF":4.1,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A MULTICENTER, RANDOMIZED, OPEN-LABEL, PLACEBO-CONTROLLED CLINICAL TRIAL OF THE EFFECT OF CETYLPYRIDINIUM CHLORIDE (CPC) MOUTHWASH AND ON-DEMAND AQUEOUS CHLORINE DIOXIDE MOUTHWASH ON SARS-COV-2 VIRAL TITER IN PATIENTS WITH MILD COVID-19","authors":"DAISUKE ONOZUKA PhD , KEIJI KONISHI MD , SATOKO TAKATERA PhD , MASAHIDE OSAKI MD , SHOUGEN SUMIYOSHI MD , YUSUKE TAKAHASHI MD , SHIGETO HAMAGUCHI MD, PhD , YASUO IMOTO PhD , SATOSHI KUTSUNA MD, PhD","doi":"10.1016/j.jebdp.2024.102040","DOIUrl":"10.1016/j.jebdp.2024.102040","url":null,"abstract":"<div><h3>Objectives</h3><div>The established effect of cetylpyridinium chloride (CPC) mouthwash on SARS-CoV-2 viral titers is unclear. No clinical trial has examined the impact of on-demand aqueous chlorine dioxide mouthwash on SARS-CoV-2 viral titer.</div></div><div><h3>Methods</h3><div>In this multicenter, 3-armed, randomized, open-label, placebo-controlled clinical trial involving mildly symptomatic COVID-19 patients, we randomly assigned them to receive 20 mL of 0.05% CPC, 10 mL of 0.01% on-demand aqueous chlorine dioxide, or 20 mL of purified water as a placebo mouthwash in a 1:1:1 ratio. The primary measurement was the SARS-CoV-2 viral titer in saliva, evaluated by a mixed-effects linear regression model.</div></div><div><h3>Results</h3><div>49 patients received CPC mouthwash (n=16), on-demand aqueous chlorine dioxide mouthwash (n=16), and placebo (n=17) between January 14, 2024, and February 20, 2024. 0.05% CPC mouthwash significantly reduced salivary viral titer at 10 minutes postuse (-0.97 log<sub>10</sub> PFU/mL; 95% CI, -1.64 to -0.30; <em>P</em> = .004), while no such effect was observed at 30 minutes (difference vs placebo, -0.26 log<sub>10</sub> PFU/mL; 95% CI, -0.92 to 0.40; <em>P</em> = .435) or 60 minutes (difference vs. placebo, -0.05 log<sub>10</sub> PFU/mL; 95% CI, -0.68 to 0.58; <em>P</em> = .877). 0.01% on-demand chlorine dioxide mouthwash did not reduce salivary viral titer at 10 minutes, 30 minutes, or 60 minutes compared to placebo.</div></div><div><h3>Conclusions</h3><div>10 minutes after using a 0.05% CPC mouthwash, the salivary viral titer of SARS-CoV-2 decreased compared to placebo. 0.01% on-demand aqueous chlorine dioxide mouthwash and placebo had no significant difference in SARS-CoV-2 viral titers.</div></div><div><h3>Trial Registration</h3><div>Japan Registry of Clinical Trials (jRCT): jRCTs031230566.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"24 4","pages":"Article 102040"},"PeriodicalIF":4.1,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142553481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ARTIFICIAL INTELLIGENCE IN DENTAL SHADE-MATCHING SHOWS PROMISING POTENTIAL FOR PRECISION IN RESTORATIVE DENTISTRY, THOUGH REQUIRING FURTHER IMPROVEMENT","authors":"AHMED YASEEN ALQUTAIBI (Reviewer)","doi":"10.1016/j.jebdp.2024.102042","DOIUrl":"10.1016/j.jebdp.2024.102042","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Shetty, S., et al. (2023). “Artificial intelligence systems in dental shade-matching: A systematic review.” J Prosthodont. <span><span>DOI: 10.1111/jopr.13805</span><svg><path></path></svg></span>.</div></div><div><h3>Source of Funding</h3><div>Information not available.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"24 4","pages":"Article 102042"},"PeriodicalIF":4.1,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
KELVIN I. AFRASHTEHFAR (REVIEWERS), LOVELY M. ANNAMMA, MAHER A. ALSHAYEB, ALAIN MANUEL CHAPLE-GIL
{"title":"IMMEDIATE IMPLANT PLACEMENT AND LOADING IN THE MAXILLARY ESTHETIC ZONE DEMONSTRATE HIGH SURVIVAL RATES, BUT ESTHETIC AND FUNCTIONAL SUCCESS DATA IS STILL NEEDED","authors":"KELVIN I. AFRASHTEHFAR (REVIEWERS), LOVELY M. ANNAMMA, MAHER A. ALSHAYEB, ALAIN MANUEL CHAPLE-GIL","doi":"10.1016/j.jebdp.2024.102036","DOIUrl":"10.1016/j.jebdp.2024.102036","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div><strong>Hamilton A, Gonzaga L, Amorim K, Wittneben JG, Martig L, Morton D, Martin W, Gallucci GO, Wismeijer D.</strong> Selection criteria for immediate implant placement and immediate loading for single tooth replacement in the maxillary esthetic zone: A systematic review and meta-analysis. Clin Oral Implants Res. 2023 Sep;34 Suppl 26:304-348. <span><span>doi:10.1111/clr.14109</span><svg><path></path></svg></span>.</div></div><div><h3>Source of Funding</h3><div>Although it is not explicitly reported, it is understood that this study was supported by the International Team for Implantology (ITI) as part of their latest consensus initiative.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review (with meta-analysis).</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"24 4","pages":"Article 102036"},"PeriodicalIF":4.1,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NOURHAN M. ALY , Mona K. El Kashlan , Nicolas Giraudeau , Maha El Tantawi
{"title":"COMPARISON OF INTRAORAL CAMERAS AND SMARTPHONES IN EARLY CHILDHOOD CARIES DETECTION: A DIAGNOSTIC ACCURACY STUDY","authors":"NOURHAN M. ALY , Mona K. El Kashlan , Nicolas Giraudeau , Maha El Tantawi","doi":"10.1016/j.jebdp.2024.102041","DOIUrl":"10.1016/j.jebdp.2024.102041","url":null,"abstract":"<div><h3>Objectives</h3><div>Early Childhood Caries (ECC) is a major public health problem affecting children worldwide. Teledentistry offers innovative approaches for ECC detection, particularly in areas with limited access to care. This study compared the accuracy of intraoral cameras and smartphones in relation to visual clinical examination in detecting ECC.</div></div><div><h3>Methods</h3><div>A prospective diagnostic accuracy study was conducted in a rural area near Alexandria, Egypt, involving children under 6 years old. An intraoral camera (C50 Full HD with fluorescence) or a smartphone (Samsung Galaxy A24) captured intraoral structures after randomizing the children into 2 groups. The reference standard was visual clinical examination under daylight without magnification or drying. Teeth were categorized using the Caries Assessment Spectrum and Treatment (CAST) index criteria based on clinical examination, intraoral camera videos and smartphone photos. Sensitivity, specificity, and accuracy were calculated for the 2 methods at 3 thresholds: enamel caries, dentin caries and enamel/dentin caries combined.</div></div><div><h3>Results</h3><div>The study included 116 children, mean (SD) age = 4.3 (1.0) years, 83.6% with untreated decay and mean (SD) number of decayed teeth = 4.03 (3.50). Both the intraoral camera and the smartphone had high specificity and accuracy at the 3 thresholds (≥90%). The lowest sensitivity was in the case of detecting enamel lesion (intraoral camera = 77.5% and smartphone = 68.5%).</div></div><div><h3>Conclusion</h3><div>Enamel caries was detected by the intraoral camera more accurately than the smartphone. Despite this, both devices exhibited high specificity and accuracy at all diagnostic thresholds. Smartphones present a good alternative for intraoral cameras in underserved areas, improving ECC detection and care.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"24 4","pages":"Article 102041"},"PeriodicalIF":4.1,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142593319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"SUCRALFATE MAY BE AN EFFECTIVE TOPICAL AGENT IN PREVENTING ORAL MUCOSITIS","authors":"LINDA L. CHENG (REVIEWER)","doi":"10.1016/j.jebdp.2024.102037","DOIUrl":"10.1016/j.jebdp.2024.102037","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Coppini M, Caponio VCA, Mauceri R, Bizzoca ME, Laino L, Lorenzo-Pouso AI, Russo D, Troiano G, Silva FFVE, Lo Muzio L, Campisi G. Efficacy of topical agents in oral mucositis prevention: Systematic review and network meta-analysis. Oral Dis. 2024. doi: <span><span>10.1111/odi.15046</span><svg><path></path></svg></span>. Epub ahead of print. PMID: <span><span>38923624</span><svg><path></path></svg></span>.</div></div><div><h3>Source of Funding</h3><div>This research has been partly funded by the Active Pharmacovigilance Project Fund (AIFA project “ADR in Dentistry in the Digital Age: From Reporting to Specialist Consultation with a Click”—“ADR in Odontoiatria nell'era informatica: dalla segnalazione alla visita specialistica con un click,” led by Prof. G. Campisi). The authors declare no conflicts of interest.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with network meta-analysis.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"24 4","pages":"Article 102037"},"PeriodicalIF":4.1,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142553574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jenny Olsson , Sylvia Hunfjörd , Oscar Braun , Birgitta Häggman-Henrikson , Anna Ljunggren
{"title":"Impact of Oral Infection on Organ Transplantation: A Systematic Review","authors":"Jenny Olsson , Sylvia Hunfjörd , Oscar Braun , Birgitta Häggman-Henrikson , Anna Ljunggren","doi":"10.1016/j.jebdp.2024.102035","DOIUrl":"10.1016/j.jebdp.2024.102035","url":null,"abstract":"<div><h3>Objectives</h3><div>Posttransplant infections may lead to dire consequences in immunocompromised organ recipients. Oral foci of infection are therefore often eliminated prior to solid organ transplantation to reduce posttransplant morbidity. However, despite increasing numbers of organ transplantations the necessity of pretransplant dental treatment and its effect on transplant outcome remains uncertain. The aim of the present systematic review was to evaluate the impact of oral foci of infection and pretransplant dental treatment on adverse events following solid organ transplantation.</div></div><div><h3>Methods</h3><div>Studies on adult patients undergoing solid organ transplantation with/without oral infection or with/without pretransplant dental treatment were eligible. An electronic search in PubMed, Scopus, Web of Science, CINAHL and Cochrane was conducted up to June 11, 2024. Screening of eligibility, data extraction and risk-of-bias assessment of the included studies with the Newcastle-Ottawa Scale were done independently by two reviewers. Data were synthesized with a narrative approach.</div></div><div><h3>Results</h3><div>In total, 4035 unique publications were identified. After full text assessment of 75 studies nine cohort studies on liver, kidney, heart and/or lung transplantation based on 727 patients were included. Two studies based on 161 patients found a significant increase of infectious complications after liver transplantation when no dental treatment was performed. Presence of oral foci increased the risk of hospitalization after kidney transplantation in one study but was associated with lower infection rate after lung transplantation in another study. No studies found significant impact on mortality or on organ rejection. Overall, the quality of the included studies was good with low or medium risk-of-bias.</div></div><div><h3>Conclusion</h3><div>To our knowledge, this is the first systematic review on the impact of oral infection on organ transplantation. The results suggest a possible link between persisting oral infection and posttransplant infectious complications, thus lending support to the elimination of oral infectious foci before solid organ transplantation.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"24 4","pages":"Article 102035"},"PeriodicalIF":4.1,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142579028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"LONG-TERM PREDICTIVE VALUE OF BLEEDING ON PROBING IN PERI‑IMPLANTITIS DIAGNOSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS","authors":"Xinbo Yu , Xinyan Lin , Feng Wang, Yiqun Wu","doi":"10.1016/j.jebdp.2024.102034","DOIUrl":"10.1016/j.jebdp.2024.102034","url":null,"abstract":"<div><h3>Objective</h3><div>This systematic review and meta-analysis aimed to evaluate the diagnostic value of bleeding on probing (BOP) for peri‑implantitis detection on implant- and patient-levels, as reported in prospective and retrospective studies with at least 5 years of follow-up.</div></div><div><h3>Materials and Methods</h3><div>A systematic search of 3 electronic databases was conducted and supplemented with a hand-search to identify clinical studies that reported the prevalence of peri‑implantitis and BOP after at least 5 years of functional loading. Random-effects meta-analyses were conducted to combine the proportions of peri‑implantitis among BOP positive implants and patients across studies. Heterogeneity was explored with subgroup analyses.</div></div><div><h3>Results</h3><div>5826 patients and 17,198 implants were included in this review. Definitions of peri‑implantitis varied between studies. Thirty studies were included for assessment. Implant-level meta-analysis was conducted in 24 studies and patient-level meta-analysis in 19 studies. Overall proportion of peri‑implantitis in BOP-positive implants was 26.5% (95% CI, 21.2 to 32.1) and 35.1% (95% CI, 27.4 to 43.1) in BOP-positive patients. Substantial heterogeneity was present, and prediction intervals were 5.2%-56% and 6.4%-71.5% at the implant- and patient-level, respectively.</div></div><div><h3>Conclusion</h3><div>Within the limitations, prevalence of peri‑implantitis was found to be around 1 third in both BOP-positive implants and patients. Prevalence varied between studies. Although a guiding clinical factor in the diagnosis of peri‑implantitis, clinicians should be aware of the significant false-positive rates of BOP.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"24 4","pages":"Article 102034"},"PeriodicalIF":4.1,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}