Journal of Evidence-Based Dental Practice最新文献

{"title":"Information for Readers","authors":"","doi":"10.1016/S1532-3382(23)00097-0","DOIUrl":"https://doi.org/10.1016/S1532-3382(23)00097-0","url":null,"abstract":"","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"23 3","pages":"Article 101906"},"PeriodicalIF":3.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49858500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASSOCIATION OF ORAL MICROBIOTA AND PERIODONTAL DISEASE WITH LUNG CANCER: A SYSTEMATIC REVIEW AND META-ANALYSIS","authors":"Kai Zhang BDS ,&nbsp;Cheng He PhD ,&nbsp;Yuan Qiu BDS ,&nbsp;Xiuyang Li PhD ,&nbsp;Jian Hu PhD ,&nbsp;Baiping Fu DMD","doi":"10.1016/j.jebdp.2023.101897","DOIUrl":"10.1016/j.jebdp.2023.101897","url":null,"abstract":"<div><h3>Objectives</h3><p>Evidence of oral microbiota perturbations has been accumulated for lung cancers. This review focused on the oral microbiota alterations in population suffering from lung cancer. In addition, we also discussed conflicting data about the association between oral microbiota dysbiosis and risk of lung cancer.</p></div><div><h3>Methods</h3><p>A systematic search was conducted in Medline, Embase, PubMed, and Cochrane Library databases. The studies evaluated diversity and abundance of oral microbes in healthy and lung cancer individuals as well as association of periodontal disease and pathogens with lung cancer. Of 3559 studies, 28 included studies were performed in qualitative analysis, and 25 studies were used in meta-analyses for quantitative assessment. Heterogeneity was analyzed by using I² and chi-squared Q test statistics. Statistical analyses were performed by using the RevMan 5.4 software.</p></div><div><h3>Results</h3><p>Compared with the control, lung cancer patients had lower alpha diversity (Shannon: SMD = -0.54; 95% CI, -0.90 to -0.19; <em>P</em> &lt; .01, I² = 71%). In nested case-control studies, individuals with decreased alpha diversity tended to have an increased risk of lung cancer (observed species: HR = 0.90; 95% CI, 0.85-0.96; <em>P</em> &lt; .01, I² = 0%; Shannon: HR = 0.89; 95% CI, 0.83-0.95; <em>P</em> &lt; .01, I²<span> = 0%). Overall, no strong evidence of association of relative abundance with specific oral microbes with lung cancers was found because of inconsistent data. No associations were found between periodontal pathogens and lung cancer risk (red complex: HR = 1.12, 95% CI: 0.42-3.02, </span><em>P</em> = .82, I² = 62%; orange complex: HR =1.77, 95% CI: 0.78-3.98, <em>P</em> = .17, I²<span> = 36%), expect for Fusobacterium nucleatum (HR = 2.27, 95% CI: 1.13-4.58, </span><em>P</em> = .02, I² = 0%). The positive association of periodontal disease with lung cancer risk was found (HR = 1.58, 95% CI: 1.25-2.00, <em>P</em> &lt; .001, I²= 0%) with increase of periodontal diseases severity (HR = 2.39, 95% CI: 1.57-3.66, <em>P</em> &lt; .001, I² = 0%). However, such association was not found in never-smoker participants (HR = 1.00, 95% CI: 0.76-1.31, <em>P</em> = .37, I²= 7%).</p></div><div><h3>Conclusions</h3><p>Lower alpha diversity of oral microbiome may be associated with a greater risk of lung cancer and might serve as a predictive signal of lung cancer risk. There was no strong evidence of relative abundance of oral microbial taxa and periodontal pathogens in lung cancer patients. Fusobacterium nucleatum might be a potential microbial candidate of biomarkers in lung cancer. Periodontal disease may be positively associated with lung cancer risk by confounding of smoking, but not an independent risk factor.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"23 3","pages":"Article 101897"},"PeriodicalIF":3.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10553240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AUTONOMOUS ROBOTIC SURGERY SEEMS PROMISING AS AN ACCURATE TECHNOLOGY FOR SINGLE-TOOTH IMPLANT PLACEMENT IN THE ESTHETIC ZONE","authors":"Kelvin I. Afrashtehfar (REVIEWERS),&nbsp;Carlos A. Jurado,&nbsp;Nour K. Assaleh,&nbsp;Hyeonjong Lee","doi":"10.1016/j.jebdp.2023.101915","DOIUrl":"10.1016/j.jebdp.2023.101915","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><p><span><span>Yang S, Chen J, Li A, Deng K, Li P, Xu S. Accuracy of autonomous robotic surgery for single-tooth </span>implant placement: a case series. </span><em>J Dent</em>. 2023;132:104451. doi:<span>10.1016/j.jdent.2023.104451</span><svg><path></path></svg>. Epub 2023 Feb 11. PMID: 36781099.</p></div><div><h3>Source of Funding</h3><p>This case series study was supported by grants from the <span>Guangdong Basic and Applied Basic Research Foundation</span>, <span>Science and Technology Projects in Guangzhou</span>, <span>Science Research Cultivation Program</span>, and <span>Clinical Research Initiation Plan of the Stomatological Hospital</span>, <span>Southern Medical University</span>, China.</p></div><div><h3>Type of Study/Design</h3><p>Case series. No a priori power calculation or pilot data. Nonconsecutive participant recruitment.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"23 3","pages":"Article 101915"},"PeriodicalIF":3.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10256083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IMPACT OF LOADING PROTOCOL OF 2-IMPLANT BAR-RETAINED MANDIBULAR OVERDENTURES ON ORAL HEALTH-RELATED QUALITY OF LIFE: A RANDOMIZED CONTROLLED TRIAL","authors":"DANIEL R. REISSMANN ,&nbsp;MARTIN SCHIMMEL ,&nbsp;DOMINIK KRAUS ,&nbsp;MILAN STOILOV ,&nbsp;MURALI SRINIVASAN ,&nbsp;NORBERT ENKLING","doi":"10.1016/j.jebdp.2023.101891","DOIUrl":"10.1016/j.jebdp.2023.101891","url":null,"abstract":"<div><h3>Objectives</h3><p><span>Aim was to assess whether immediate loading (IL) is more effective than delayed loading (DL) for 2-implant bar-retained mandibular overdentures in terms of oral health-related </span>quality of life (OHRQoL) improvement over a period of 24-month.</p></div><div><h3>Methods</h3><p>In this randomized controlled trial<span><span>, 32 edentulous patients (mean age: 65.7 ± 10.6 years, 50.0% female) were included. Potential participants had to be unsatisfied with the retention of their current mandibular complete denture and demanded implant </span>treatment for inclusion in the study. OHRQoL was assessed with the 49-item Oral Health Impact Profile (OHIP) at baseline before treatment and 1, 3, 6, 12, and 24 months after implant loading and insertion of implant-retained bars for overdenture support. A mixed-effects model with patients as random effect and an unstructured covariance matrix was developed to address repeated outcome measurement.</span></p></div><div><h3>Results</h3><p>Patients’ OHRQoL impairment at baseline was substantial indicated by mean OHIP summary score of 45.1 points. OHIP summary scores decreased substantially from baseline to 1-month follow-up to a mean of 33.5 points (<em>P</em> = .020). OHRQoL further improved during study period indicated by OHIP summary score of 25.7 points at 24-month follow-up. Raw treatment effects (IL vs. DL) ranged from -1.2 OHIP points for 12-month follow-up to 5.8 OHIP points for 24-month follow-up. Assuming constant treatment and time effects, treatment effect was small and not statistically significant (-0.7 OHIP points; <em>P</em>= .918).</p></div><div><h3>Conclusion</h3><p>A 2-implant bar-retained mandibular overdentures substantially improves OHRQoL over a period of at least 24 months. There seems to be no significant effect of implant loading protocol.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"23 3","pages":"Article 101891"},"PeriodicalIF":3.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10553236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Statement of Purpose/Levels of Evidence","authors":"","doi":"10.1016/S1532-3382(23)00096-9","DOIUrl":"https://doi.org/10.1016/S1532-3382(23)00096-9","url":null,"abstract":"","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"23 3","pages":"Article 101905"},"PeriodicalIF":3.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49858501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SMOKERS MAY BE SUBJECT TO A HIGHER RISK OF SCHNEIDERIAN MEMBRANE PERFORATION THAN NONSMOKERS DURING MAXILLARY SINUS AUGMENTATION","authors":"Ahmed Yaseen Alqutaibi (REVIEWERS),&nbsp;Abdulmajeed Abdulaziz Baik,&nbsp;Sary Borzangy","doi":"10.1016/j.jebdp.2023.101887","DOIUrl":"10.1016/j.jebdp.2023.101887","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><p><span><span>Association between smoking and Schneiderian membrane perforation during </span>maxillary sinus floor augmentation: A </span>systematic review<span> and meta-analysis. Wang, X., Ma, S., Lin, L., &amp; Yao, Q. Clinical Implant Dentistry and Related Research. 2022., 25.1: 166–176.</span></p></div><div><h3>Source of Funding</h3><p><span>National Natural Science Foundation of China</span>, Grant/Award Number: <span>81801021</span>; <span>Hunan Provincial Health Commission</span>, Grant/Award Number: <span>B202308056991</span>.</p></div><div><h3>Type of Study/Design</h3><p>Systematic review and meta-analysis</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"23 3","pages":"Article 101887"},"PeriodicalIF":3.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10256079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between two different local hemostatic methods for dental extractions in patients on dual antiplatelet therapy: a within-person, single-blind, randomized study","authors":"Bruno Guardieiro ,&nbsp;Marcela Alves Santos-Paul ,&nbsp;Remo Holanda de Mendonça Furtado ,&nbsp;Talia Dalçóquio ,&nbsp;Rocío Salsoso ,&nbsp;Itamara Lúcia Itagiba Neves ,&nbsp;Ricardo Simões Neves ,&nbsp;Cyrillo Cavalheiro Filho ,&nbsp;Luciano Moreira Baracioli ,&nbsp;José Carlos Nicolau","doi":"10.1016/j.jebdp.2023.101863","DOIUrl":"10.1016/j.jebdp.2023.101863","url":null,"abstract":"<div><h3>Background</h3><p>Dual antiplatelet therapy (DAPT) provides additional risk reduction of ischemic events compared to aspirin monotherapy, at cost of higher bleeding risk. There are few data comparing new techniques for reducing bleeding after dental extractions in these patients.</p></div><div><h3>Purpose</h3><p>This study investigated the effectiveness of the HemCon Dental Dressing (HDD) compared to oxidized cellulose gauze.</p></div><div><h3>Materials and methods</h3><p>This randomized study included 60 patients on DAPT who required at least two dental extractions (120 procedures). Each surgical site was randomized to HDD or oxidized regenerated cellulose gauze as the local hemostatic method. Intra-oral bleeding time was measured immediately after the dental extraction and represents our main endpoint for comparison of both hemostatic agents. Prolonged bleeding, platelet reactivity measured by Multiplate Analyser (ADPtest and ASPItest) and tissue healing comparison after 7 days were also investigated.</p></div><div><h3>Results</h3><p>Intra-oral bleeding time was lower in HDD compared with control (2 [2-5] vs. 5 [2-8] minutes, <em>P</em>=0.001). Prolonged postoperative bleeding was observed in 7 cases (11.6%), all of them successfully managed with local sterile gauze pressure. More HDD treated sites presented better healing when compared with control sites [21 (36.8%) vs. 5 (8.8%), <em>P</em>=0.03]. There was poor correlation between platelet reactivity and intra-oral bleeding time.</p></div><div><h3>Conclusions</h3><p>In patients on DAPT, HDD resulted in a lower intra-oral bleeding time compared to oxidized cellulose gauze after dental extractions. Moreover, HDD also seems to improve healing conditions.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"23 3","pages":"Article 101863"},"PeriodicalIF":3.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10256080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"INTRAORAL SCANNING AND CONVENTIONAL IMPRESSION MAY HAVE SIMILAR TIME EFFICIENCY FOR COMPLETE COVERAGE CROWNS AND THREE-UNIT FIXED TOOTH-SUPPORTED PROSTHESES","authors":"Iman Abd-Elwahab Radi (REVIEWERS),&nbsp;Mohamed Amr ElKhashab","doi":"10.1016/j.jebdp.2023.101894","DOIUrl":"10.1016/j.jebdp.2023.101894","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><p><span>Bandiaky ON, Le Bars P, Gaudin A, Hardouin JB, Cheraud-Carpentier M, Mbodj EB, Soueidan A. Comparative assessment of complete-coverage, fixed tooth-supported prostheses fabricated from digital scans or conventional impressions: A systematic review and meta-analysis. J Prosthet Dent. 2022 Jan;127(1):71–79. doi: </span><span>10.1016/j.prosdent.2020.09.017</span><svg><path></path></svg>. Epub 2020 Nov 2. PMID: 33,143,901.</p></div><div><h3>Source of Funding</h3><p>Information not available</p></div><div><h3>Type of Study/Design</h3><p>Systematic review with meta-analysis of data.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"23 3","pages":"Article 101894"},"PeriodicalIF":3.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10553238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE CONTENTS, METHODS, AND ASSESSMENT OF EVIDENCE-BASED DENTISTRY EDUCATION: A SCOPING REVIEW","authors":"Qiujing Li BDS ,&nbsp;Shijia Tang BDS ,&nbsp;Xueqian Yu MS ,&nbsp;Anne-Marie Glenny Phd ,&nbsp;Fang Hua Phd","doi":"10.1016/j.jebdp.2023.101895","DOIUrl":"10.1016/j.jebdp.2023.101895","url":null,"abstract":"<div><h3>Objective</h3><p><span>With evidence-based dentistry (EBD) having a far-reaching influence on oral healthcare, dental educators worldwide have made joint efforts to integrate EBD-related knowledge and skills into </span>dental education. The present scoping review aims to identify and summarize the existing teaching contents, teaching methods, and assessment strategies of EBD education.</p></div><div><h3>Methods</h3><p>Electronic (PubMed and Embase) and manual searches were performed to identify articles related to both “dental education” and “evidence-based practice.” Based on predetermined eligibility criteria, articles were selected by 2 reviewers, independently and in duplicate. Data synthesis was conducted based on teaching contents, teaching strategies, and teaching assessment.</p></div><div><h3>Results</h3><p>Of the 1758 articles found in the literature searches, 74 were deemed eligible and included in this review. A total of 4 basic skills (problem formulation, literature searching, critical appraisal, and research methodology), 5 teaching methods, and 6 assessment strategies were identified. In most of the articles, 2, or more skills were taught, and a combination of traditional strategies for teaching and its assessment (eg, courses and questionnaire survey) was involved. Other teaching methods, such as journal clubs and workshops, were seldom used, and validated assessment tools accounted for a relatively small proportion of the assessment strategies involved.</p></div><div><h3>Conclusions</h3><p>The contents, methods and assessment of EBD education have been widely studied and discussed. However, the current literature focuses mainly on teaching of critical appraisal skills, traditional teaching methods, and short-term outcome assessments. Future research in this area can be aimed at integrating all EBD-related skills into educational models, studying multifaceted teaching approaches, and developing comprehensive teaching outcome assessment methods based on validated tools and dental patient-reported outcomes.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"23 3","pages":"Article 101895"},"PeriodicalIF":3.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10256078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EFFICACY AND SAFETY OF A DEXAMETHASONE-BASED MOUTHWASH TO PREVENT CHEMOTHERAPY-INDUCED STOMATITIS IN WOMEN WITH BREAST CANCER: A MULTICENTRE, OPEN-LABEL, RANDOMISED PHASE 2 STUDY","authors":"Sayaka Kuba M.D., PhD ,&nbsp;Shigeto Maeda M.D., PhD ,&nbsp;Kenichiro Shibata M.D., PhD ,&nbsp;Sakiko Soutome D.D.S., PhD ,&nbsp;Kosho Yamanouchi M.D., PhD ,&nbsp;Megumi Matsumoto M.D., PhD ,&nbsp;Aya Tanaka M.D., PhD ,&nbsp;Michi Morita M.D., PhD ,&nbsp;Toshiko Hatachi M.D. ,&nbsp;Ryota Otsubo M.D., PhD ,&nbsp;Hiroshi Yano M.D., PhD ,&nbsp;Yumiko Kawashita D.D.S., PhD ,&nbsp;Shuntaro Sato PhD ,&nbsp;Hideki Taniguchi M.D., PhD ,&nbsp;Kengo Kanetaka M.D., PhD ,&nbsp;Masahiro Umeda D.D.S., PhD ,&nbsp;Takeshi Nagayasu M.D., PhD ,&nbsp;Susumu Eguchi M.D., PhD","doi":"10.1016/j.jebdp.2023.101896","DOIUrl":"10.1016/j.jebdp.2023.101896","url":null,"abstract":"<div><h3>Purpose</h3><p><span><span>No standard approach other than oral care is available for preventing chemotherapy-induced stomatitis </span>in patients with breast cancer. In this randomized, controlled phase 2 trial, we aimed to assess the efficacy and safety of a dexamethasone-based </span>mouthwash in preventing chemotherapy-induced stomatitis in patients with early breast cancer.</p></div><div><h3>Basic procedures</h3><p><span>Patients with breast cancer scheduled for epirubicin<span><span> and cyclophosphamide (EC) or </span>docetaxel and cyclophosphamide (TC) therapy were selected and allocated in a 1:1 ratio to the intervention and control groups. The intervention group received chemotherapy, oral care, and a dexamethasone-based mouthwash, whereas the control group received chemotherapy and oral care. The primary endpoint was the incidence of stomatitis. This was a phase 2 study, and the significance level for the analysis of the primary endpoint was set </span></span><em>a priori</em> at 0.2.</p></div><div><h3>Main findings</h3><p>Data pertaining to 58 patients in the control group and 59 patients in the intervention group were analyzed. Stomatitis incidence was 55% and 38% in the control and intervention groups, respectively (risk ratio, 0.68; 80% confidence interval, 0.52-0.88; <em>P</em> = .052). Stomatitis severity was lower in the intervention group than in the control group (<em>P</em> = .03). The proportion of patients who adhered to the mouthwash regimen was 87% (interquartile range, 67.8%-95.3%). No severe oral infections were observed.</p></div><div><h3>Principal conclusions</h3><p>The dexamethasone-based mouthwash safely reduced stomatitis incidence and severity in patients receiving chemotherapy for early breast cancer. Phase 3 clinical trials are warranted for validating our results.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"23 3","pages":"Article 101896"},"PeriodicalIF":3.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10553239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}