Divesh Sardana , Johyun Lee , Cynthia KY Yiu , Kar Yan Li
{"title":"EFFECTIVENESS OF PHENTOLAMINE MESYLATE IN REVERSAL OF LOCAL ANESTHESIA: SYSTEMATIC REVIEW AND META-ANALYSIS","authors":"Divesh Sardana , Johyun Lee , Cynthia KY Yiu , Kar Yan Li","doi":"10.1016/j.jebdp.2023.101861","DOIUrl":"10.1016/j.jebdp.2023.101861","url":null,"abstract":"<div><h3>Background</h3><p>The aim of the present paper is to summarize the effectiveness of Phentolamine<span> mesylate on the reversal of local anesthesia (LA).</span></p></div><div><h3>Methodology</h3><p><span>Seven electronic databases were searched for randomized clinical trials </span>in patients who received LA (population) and either received a Phentolamine injection (intervention) after LA compared to placebo or sham (control) to cause a return of normal sensation (outcome). Risk of bias assessment was performed using Cochrane risk of bias assessment tool 2.0. The hazard ratio (HR) was calculated as the event (time to return to the normal sensation) was a time-dependent event, as well as the weighted mean difference (WMD), was computed. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) was used to assess the certainty of the evidence.</p></div><div><h3>Results</h3><p><span>Ten studies met our inclusion criteria and were included in this review. After pooling the results quantitatively, the value of the HR in the tongue was 0.56 (95% CI: 0.41–0.75, </span><em>P</em><span><.001); in lower lip, the value was 0.56 (95% CI: 0.38–0.83, </span><em>P</em> = .004) and for upper lip, the value was 0.50 (95% CI: 0.31–0.80, <em>P</em> = .004). The WMD for the time to return for normal sensation was -47.71 min for the tongue (95% CI: -73.63 to -21.80 min, <em>P</em><.001), -73.29 min for lower lip (95% CI: -88.41 to -58.16 min, <em>P</em><.001) and -86.86 min for upper lip (95% CI: -101.16 to -72.57 min, <em>P</em><.001). There is a high certainty of evidence that patients who have been administered local anesthesia may achieve faster recovery of normal sensation in tongue, and moderate certainty of evidence for return of normal sensation in lower lip and upper lip, if Phentolamine was administered after the local anesthesia. The adverse effects were reported in a few studies and were minor, not necessitating any medical intervention.</p></div><div><h3>Conclusions</h3><p>Phentolamine might be a useful adjunct in patients who desire an earlier return of normal sensation and function after local anesthesia. Future research should be directed to study the cost-effectiveness or dental patient-reported outcomes of Phentolamine after local anesthetic injections.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10669908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A LÖVGREN , A ILGUNAS , B HÄGGMAN-HENRIKSON , B ELIAS , O AL ROUDINi , C. M VISSCHER , F LOBBEZOO , A WÄNMAN , P LIV
{"title":"ASSOCIATIONS BETWEEN SCREENING FOR FUNCTIONAL JAW DISTURBANCES AND PATIENT REPORTED OUTCOMES ON JAW LIMITATIONS AND ORAL BEHAVIORS","authors":"A LÖVGREN , A ILGUNAS , B HÄGGMAN-HENRIKSON , B ELIAS , O AL ROUDINi , C. M VISSCHER , F LOBBEZOO , A WÄNMAN , P LIV","doi":"10.1016/j.jebdp.2023.101888","DOIUrl":"10.1016/j.jebdp.2023.101888","url":null,"abstract":"<div><h3>Objectives</h3><p>Temporomandibular disorders (TMDs) is a collective term for pain and functional disturbances related to the jaw muscles and the temporomandibular joint<span>. In contrast to screening for orofacial pain, knowledge is limited on the association between patient-reported outcomes and screening for joint-related functional jaw disturbances. Therefore, our aim was to evaluate the association between a screening question for functional jaw disturbances, and disease-specific outcome measures for functional jaw limitations and oral behaviors.</span></p></div><div><h3>Methods</h3><p>This study included 299 individuals (201 women; 20-69 years, median 37.0) in a general population sample from Västerbotten, Northern Sweden in 2014. A single screening question for functional jaw disturbances “Does your jaw lock or become stuck once a week or more?” was used to categorize individuals as cases or controls. Patient-reported outcomes on functional jaw disturbances were assessed with the 20-item jaw functional limitation scale (JFLS-20) and oral behaviors with the 21-item Oral Behaviors Checklist (OBC-21).</p></div><div><h3>Results</h3><p>The strongest predictive probability to have a positive screening outcome was functional jaw limitations related to mobility (AUC<sub>boot</sub>=0.78, 95 CI:0.71-0.86, <em>P</em> < .001), followed by limitations related to communication (AUC<sub>boot</sub> = 0.74, 95 CI:0.63-0.80, <em>P</em><span> < .001) and mastication (AUC</span><sub>boot</sub> = 0.73, 95 CI:0.66-0.81, <em>P</em> < .001). The frequency of oral behaviors was not significantly associated with a positive screening outcome (AUC<sub>boot</sub> = 0.65, 95 CI:0.55-0.72, <em>P</em> = .223).</p></div><div><h3>Conclusions</h3><p>Self-reported functional limitations, but not oral behaviors, are strongly associated with a single screening question for frequent functional jaw disturbances. This finding provides support for incorporating a question on jaw catching/locking once a week or more in screening instruments for TMDs.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10553237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"OCCLUSAL APPLIANCES MIGHT BE CLINICALLY EFFICIENT IN TREATING SLEEP BRUXISM","authors":"Iman AbdelWahab Radi (REVIEWER)","doi":"10.1016/j.jebdp.2023.101890","DOIUrl":"10.1016/j.jebdp.2023.101890","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><p><span>Minakuchi H, Fujisawa M, Abe Y, Iida T, Oki K, Okura K, Tanabe N, Nishiyama A. Managements of sleep bruxism in adult: A </span>systematic review. Jpn Dent Sci Rev. 2022; 58:124-36.</p></div><div><h3>Source of Funding</h3><p>None was reported.</p></div><div><h3>Type of Study/Design</h3><p>Systematic review.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10239576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Authors","authors":"","doi":"10.1016/S1532-3382(23)00098-2","DOIUrl":"https://doi.org/10.1016/S1532-3382(23)00098-2","url":null,"abstract":"","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49858499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THREE-YEAR OUTCOME OF DIODE LASER PULPOTOMY OF PRIMARY MOLARS USING THREE PULP CAPPING AGENTS: A SPLIT-MOUTH RANDOMIZED CLINICAL TRIAL","authors":"Roza Haghgoo , Fatemeh Molaasadolah , Fateme Taghizade , Ghassem Ansari , Saeed Asgary","doi":"10.1016/j.jebdp.2023.101920","DOIUrl":"10.1016/j.jebdp.2023.101920","url":null,"abstract":"<div><h3>Objectives</h3><p>Pulpotomy<span><span><span> is the most commonly performed treatment for asymptomatic </span>primary molars with exposed </span>dental pulp<span><span>. This study aimed to assess the clinical /radiographic success of diode laser pulpotomy with mineral trioxide aggregate (MTA), </span>calcium hydroxide<span> (CH), and calcium-enriched mixture (CEM) cement as pulp capping agents.</span></span></span></p></div><div><h3>Methods</h3><p><span>This split-mouth randomized clinical trial was conducted initially on 34 children aged 3-8 years but 4 patients left the study before the first follow-up visit and the study was accomplished and analyzed with 30 cases. The patients had at least 3 first/second molars with deep caries that in radiographic evaluation revealed that they required pulpotomy. Following pulpotomy, the pulp stump was irradiated with diode laser (noncontact mode, 632 nm, 30 mW power) as photobiomodulation mode. Pulp tissue was then capped with MTA, CH, or CEM cement (n = 30 in each group). Reinforced </span>zinc oxide eugenol<span> was applied over the capping agent, and the teeth were restored with stainless steel crowns. Teeth were clinically/radiographically assessed at 6, 12, 18, and 36 months, after treatment. Data were analyzed by Cochran and McNemar tests.</span></p></div><div><h3>Results</h3><p>All 30 patients showed up for clinical/radiographic follow-ups for up to 36 months. Regarding clinical outcomes, the 6-, 12-, 18-, and 36-month success rates of all experimental groups were nearly similar with no significant difference (<em>p</em> > .05). Regarding radiographic outcomes, the 6-month success rates were similar among the groups (<em>p</em> > .05); however, the 12-, 18-, and 36-month outcomes of CEM and MTA groups were similar but significantly superior to that of CH group (<em>p</em> < .05).</p></div><div><h3>Conclusion</h3><p>Diode laser irradiation and subsequent capping of pulp tissue with MTA or CEM cement can be employed for pulpotomy of primary molars.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2023-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48954145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COMPARISONS BETWEEN DIGITAL-GUIDED AND NONDIGITAL PROTOCOL IN IMPLANT PLANNING, PLACEMENT, AND RESTORATIONS: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS","authors":"BILU XIANG , JIAYI YU , JIAYI LU , ZEPING YAN","doi":"10.1016/j.jebdp.2023.101919","DOIUrl":"10.1016/j.jebdp.2023.101919","url":null,"abstract":"<div><h3>Objectives</h3><p>The present study aimed to systematically review the current randomized clinical trials (RCTs) with respect to computer-aided design/computer-aided manufactured (CAD/CAM) techniques in the process of implant planning, placement, and rehabilitation.</p></div><div><h3>Materials and Methods</h3><p>Four independent reviewers conducted an electronic and manual literature search using several databases, including the National Library of Medicine (MEDLINE-PubMed), Cochrane Central Register of Controlled Trials (CENTRAL), and EMBASE. Articles were included if they were RCTs involving the interventions regarding the computer-guided impression, placement, and manufacturing process. The outcomes of interest include clinical and patient-reported outcomes and time efficiency. A meta-analysis was conducted to evaluate the time efficiency, pain severity, accuracy of implant placement, and postsurgery marginal bone level.</p></div><div><h3>Results</h3><p>A total of 39 and 25 articles were included in the qualitative and quantitative analysis, respectively. The results of the meta-analysis showed that significantly less time was spent performing the digital impression procedure than the conventional impression (<em>P</em> = .002). In addition, the average adjustment time of the final prosthesis was significantly less than the nondigital fabricated prosthesis (<em>P</em> = .0005). Computer-guided groups reported significantly lower painkiller consumption compared to control groups (<em>P</em> = .03).</p></div><div><h3>Conclusions</h3><p>Digital impressions and CAD/CAM procedures are time-saving and provide stable and predictable outcomes. Moreover, computer-guided surgery can effectuate an accurate implant placement and less postsurgery discomfort.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2023-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44852303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
YUNG ON CHENG , SAJESH K VEETTIL , M SAKIL SYEED , NARESH Y. SHETTY , DIVYA GOPINATH
{"title":"COMPARATIVE EFFICACY OF THERAPEUTIC INTERVENTIONS FOR THE MANAGEMENT OF RECURRENT APHTHOUS ULCERS: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS","authors":"YUNG ON CHENG , SAJESH K VEETTIL , M SAKIL SYEED , NARESH Y. SHETTY , DIVYA GOPINATH","doi":"10.1016/j.jebdp.2023.101918","DOIUrl":"10.1016/j.jebdp.2023.101918","url":null,"abstract":"<div><h3>Background</h3><p>Recurrent aphthous ulceration (RAU) is an oral condition cavity affecting 2.5 billion people worldwide. We aimed to assess the comparative efficacy and safety of available interventions in the management of RAU.</p></div><div><h3>Materials and Methods</h3><p>An electronic search of 3 databases (Medline, CENTRAL, Scopus) was performed to identify randomized control trials evaluating the efficacy of RAU interventions published until December 2022. A network meta-analysis (NMA) was conducted on 4 outcomes: reduction in pain, duration of ulceration, the diameter of ulceration, and area of ulceration. The interventions are then arranged using the surface area under cumulative ranking (SUCRA).</p></div><div><h3>Results</h3><p><span>A total of 38 trials involving 2773 patients were included were included in quantitative synthesis by NMA. Our analysis showed that Diode laser [MD, -4.865 ± 1.951 (95%CI = (-8.690, -1.041)] was the most effective in reducing the pain score followed by Amlexanox [MD, -2.673 ± 1.075 (95%CI = -4.779, -0.566)]. Iralvex performed the best in reducing the duration of ulceration [MD, -6.481 ± 1.841 (95%CI = -10.090, -2.872)]. Diode laser, </span><em>acacia nilotica</em><span> with licorice formulation</span><em>,</em> and amlexanox were the most effective interventions for reduction of ulcer diameter. Majority of the trials reported absence of any adverse effects and those reported were mild.</p></div><div><h3>Conclusion</h3><p>Our NMA has identified several interventions to be more effective than a placebo. Laser therapy may be an option for promoting pain management, however, most have only been tested in 1 or 2 trials. Further studies with rigorous methodology on larger samples are recommended to strengthen the current evidence.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2023-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44166983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chin-Wei Wang (REVIEWERS), Chia-Yu Wu, May-Show Chen
{"title":"RECONSTRUCTIVE THERAPY OF PERI‑IMPLANTITIS, COMPARED TO RESECTIVE INTERVENTION, MAY RESULT IN LESS PERI‑IMPLANT MUCOSAL RECESSION","authors":"Chin-Wei Wang (REVIEWERS), Chia-Yu Wu, May-Show Chen","doi":"10.1016/j.jebdp.2023.101917","DOIUrl":"10.1016/j.jebdp.2023.101917","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><p><span>Sanz-Martín I, Cha J-K, Sanz-Sánchez I, Figuero E, Herrera D, Sanz M. Changes in peri‑implant soft tissue levels following surgical treatment of peri‑implantitis: a systematic review and meta-analysis. </span><span><em>Clin </em><em>Oral Implants</em><em> Res</em></span>. 2021;32(suppl 21):230-244. <span>https://doi.org/10.1111/clr.13840</span><svg><path></path></svg>.</p></div><div><h3>Source of Funding</h3><p>No financial support.</p></div><div><h3>Type of Study/Design</h3><p>Systematic review with meta-analysis.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45876066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"WEARING ORTHODONTIC APPLIANCES MAY NOT IMPACT THE ORAL HEALTH-RELATED QUALITY OF LIFE (OHRQOL) OF CHILDREN AND ADOLESCENTS","authors":"EMAN BAKHURJI (REVIEWER)","doi":"10.1016/j.jebdp.2023.101912","DOIUrl":"10.1016/j.jebdp.2023.101912","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><p>Impacts of using orthodontic<span> appliances on the quality of life<span> of children and adolescents: systematic review and meta-analysis. Vidigal MTC, Mesquita CM, de Oliveira MN, de Andrade Vieira W, Blumenberg C, Nascimento GG, Pithon MM, Paranhos LR. Eur J Orthod. 2022 Aug 16; 44(4):359-368.</span></span></p></div><div><h3>Source of Funding</h3><p>Government.</p></div><div><h3>Type of Study/Design</h3><p>Systematic review with meta-analysis of data.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43746669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EVIDENCE SUPPORTS SHORT-TERM CLINICAL BENEFITS OF ADJUNCTIVE ORAL PROBIOTICS FOLLOWING SCALING AND ROOT PLANING TREATMENT","authors":"Ya-Hsin Wu, Chin-Wei Wang, Yvonne Kapila","doi":"10.1016/j.jebdp.2023.101916","DOIUrl":"10.1016/j.jebdp.2023.101916","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><p><span><span>Hu D, Zhong T, Dai Q. Clinical efficacy of probiotics<span> as an adjunctive therapy to scaling and root planning in the management of periodontitis: a </span></span>systematic review and meta-analysis of randomized controlled trails. J Evid Based Dent Pract. 2021;21(2):101547. doi:</span><span>10.1016/j.jebdp.2021.101547</span><svg><path></path></svg>.</p></div><div><h3>Source of Funding</h3><p>Self-funded.</p></div><div><h3>Type of Study/Design</h3><p>Systematic review with meta-analysis of data.</p></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44550402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}