Nouran Nabil , Aly A. Sharaf , Marwa M. Essawy , Reham S. Soliman
{"title":"The Desensitizing Effect of Nanosilver Fluoride Compared to Photobiomodulation Therapy in Molar-Incisor Hypomineralization: A Randomized Clinical Trial","authors":"Nouran Nabil , Aly A. Sharaf , Marwa M. Essawy , Reham S. Soliman","doi":"10.1016/j.jebdp.2025.102139","DOIUrl":"10.1016/j.jebdp.2025.102139","url":null,"abstract":"<div><h3>Objectives</h3><div>Molar-incisor hypomineralization (MIH) can cause hypersensitivity. This study compared nanosilver fluoride (NSF) and photobiomodulation therapy (PBMT) regarding desensitization in MIH-affected first permanent molars (FPMs) and plaque reduction.</div></div><div><h3>Methods</h3><div>Children aged 7-10 years, with 120 hypersensitive MIH-affected FPMs, were randomly assigned to receive NSF or PBMT. Hypersensitivity was assessed using the Schiff Cold Air Sensitivity Scale (SCASS) at baseline, after 15 minutes and 1 month. Plaque accumulation was assessed using the modified plaque index (PlI) of Silness and Löe at baseline and after 1 month. T-test and Mann–Whitney U test were used to compare groups. Intragroup comparisons were done using paired t-test and Friedman test. Multilevel ordinal logistic regression analysis was used to assess the effect of treatment on the outcomes, controlling for confounders.</div></div><div><h3>Results</h3><div>The study included 40 children, mean ± SD age = 8.03 ± 1.13 years. There was significantly less sensitivity and greater plaque reduction in the NSF than the PBMT group after 1 month (<em>P</em> < .05). NSF and PBMT significantly reduced sensitivity over time (<em>P</em> < .001), with the lowest scores after 1 month. In multilevel regression, NSF was associated with significantly less sensitivity than PBMT after 1 month (AOR = 0.18, 95% CI: 0.07, 0.51, <em>P</em> = .001). While both groups had reduced plaque accumulation, the decrease was significant only in the NSF group (<em>P</em> < .001).</div></div><div><h3>Conclusion</h3><div>NSF and PBMT reduced sensitivity associated with MIH and provided immediate pain relief. However, NSF was superior due to its longer-lasting effects on sensitivity and additional benefit in plaque reduction.</div></div><div><h3>Clinical significance</h3><div>NSF offers a promising alternative to PBMT in desensitizing MIH-related hypersensitivity, particularly for patients with limited access to laser therapy.</div></div><div><h3>Trial registration</h3><div>The trial was registered in the clinicaltrials.gov registry (# NCT06348849).</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 3","pages":"Article 102139"},"PeriodicalIF":4.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143777359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SARAH M. KHAIRY, DALIA M. TALAAT, KARIN M.L. DOWIDAR
{"title":"REMINERALIZATION OF WHITE SPOT LESIONS IN PRIMARY TEETH USING AN INTENSIVE APPLICATION PROTOCOL OF CURODONT REPAIR FLUORIDE PLUS, MI VARNISH OR DURAPHAT VARNISH (RANDOMIZED CONTROLLED CLINICAL TRIAL)","authors":"SARAH M. KHAIRY, DALIA M. TALAAT, KARIN M.L. DOWIDAR","doi":"10.1016/j.jebdp.2025.102163","DOIUrl":"10.1016/j.jebdp.2025.102163","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the efficacy of intensive application of Curodont Repair Fluoride Plus (CRFP), MI varnish or Duraphat in treating white spot lesions (WSLs) of primary teeth over 12-months follow-up.</div></div><div><h3>Methods</h3><div>Sixty-six high-caries-risk preschooler children with active WSLs in their primary anterior teeth, were randomly allocated to receive intensive application of CRFP, MI varnish, or Duraphat. Lesions were assessed using ICDAS-II criteria and DIAGNOdent laser fluorescence at baseline and after 3, 6, 9, and 12 months. lesion size changes were evaluated using standardized photographs after 3, 6, and 12 months. Visual analogue scale was used for assessing esthetic improvement after 6 and 12 months.</div></div><div><h3>Results</h3><div>Multivariable logistic regression models addressing caries arrest (using ICDAS-II severity scores) and reducing lesion activity revealed that CRFP achieved significantly higher odds of caries arrest (AOR=6.46, <em>P</em> = .011) and decreasing number of active lesions (AOR=19.86, <em>P</em> = .003) when compared to Duraphat. No significant difference was found between MI varnish and Duraphat regarding caries arrest (AOR=2.07, <em>P</em> = .242) or reducing lesion activity (AOR=4.11, <em>P</em> = .064). All study materials resulted in significant percent reduction in DIAGNOdent readings across time (<em>P</em> < .001). CRFP reduced DIAGNOdent readings significantly when compared to Duraphat at all time intervals while a significant difference appeared between CRFP and MI varnish groups only after 9 and 12 months. All the materials reduced lesion size significantly, with the greatest reduction achieved by CRFP, resulting in moderate to exceptional esthetic improvement.</div></div><div><h3>Conclusion</h3><div>Intensive application of CRFP exhibited superior remineralization and esthetic improvement of WSLs compared to MI varnish or Duraphat.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 3","pages":"Article 102163"},"PeriodicalIF":4.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144147960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
YU-HSUAN PI (Reviewers), WEI-CHUN LIN, CHIA-YU CHEN, CHIN-WEI WANG
{"title":"LASER-MICROTEXTURED ABUTMENTS MAY HELP REDUCE INFLAMMATION AND PERI‑IMPLANT TISSUE REMODELING FOLLOWING IMPLANT PLACEMENT","authors":"YU-HSUAN PI (Reviewers), WEI-CHUN LIN, CHIA-YU CHEN, CHIN-WEI WANG","doi":"10.1016/j.jebdp.2025.102162","DOIUrl":"10.1016/j.jebdp.2025.102162","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Aldrin Huamán‐Mendoza, Renata Bommarito, Marcos Hideki Hagy, Nathalia Vilela, Marcelo Munhóes Romano, Mariana Minatel Braga, Claudio Mendes Pannuti, Marinella Holzhausen. Effect of laser‐microtextured abutments on peri‐implant outcomes: a systematic review and meta‐analysis. Clinical Oral Investigations (2024) 28:388 <span><span>https://doi.org/10.1007/s00784-024-05785-1</span><svg><path></path></svg></span></div></div><div><h3>Source of Funding</h3><div>This research received no specific grant from any funding agency.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with meta-analysis.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 3","pages":"Article 102162"},"PeriodicalIF":4.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144170467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MOBILE TEETH ARE AT A HIGHER RISK OF BEING EXTRACTED OR LOST THAN NONMOBILE TEETH IN PERIODONTITIS PATIENTS UNDER SUPPORTIVE CARE","authors":"SATHEESH ELANGOVAN (REVIEWER)","doi":"10.1016/j.jebdp.2024.102038","DOIUrl":"10.1016/j.jebdp.2024.102038","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Peditto M, Rupe C, Gambino G, Di Martino M, Barbato L, Cairo F, Oteri G, Cavalcanti R. Influence of mobility on the long-term risk of tooth extraction/loss in periodontitis patients. A systematic review and meta-analysis. J Periodontal Res. 2024 May 20. <span><span>doi: 10.1111/jre.13286</span><svg><path></path></svg></span>.</div></div><div><h3>Source of Funding</h3><div>No funding received.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with meta-analysis of data.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 3","pages":"Article 102038"},"PeriodicalIF":4.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144240753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"BLUEPRINT PERSONA AND INFORMATION AND COMMUNICATION TECHNOLOGY INTERVENTIONS: ADDRESSING UNMET NEEDS IN BURNING MOUTH SYNDROME CARE","authors":"FEDERICA CANFORA , MAURO CATALDI , MICHELE DAVIDE MIGNOGNA , GIULIA OTTAVIANI , STEFANIA LEUCI , NOEMI COPPOLA , GIUSEPPE PECORARO , VINCENZO DE LUCA , ELENA SALVATORE , GIOVANNI DELL'AVERSANA ORABONA , VINCENZO ABBATE , GUIDO IACCARINO , MICHELE VIRGOLESI , SARA APRANO , CLAUDIA VETRANI , DANIELA LEMMO , MASSIMO ARIA , MADDALENA ILLARIO , DANIELA ADAMO","doi":"10.1016/j.jebdp.2024.102047","DOIUrl":"10.1016/j.jebdp.2024.102047","url":null,"abstract":"<div><h3>OBJECTIVES</h3><div>This study aimed to create a Blueprint Persona for Burning Mouth Syndrome (BMS) patients, focusing on Unmet needs that digital solutions can address.</div></div><div><h3>METHODS</h3><div>An interdisciplinary focus group formulated the BMS Blueprint Persona by discussing clinical data and survey results regarding education, informatics skills, and perceived unmet needs, collected from 500 BMS patients between 2022 and 2023.</div></div><div><h3>RESULTS</h3><div>The BMS Blueprint Persona, named Anna, represents a typical BMS patient profile: a young-old woman with limited computer skills who experiences anxiety, depression, and insomnia, has memory issues leading to medication adherence challenges, is obese due to overeating, and spends much time watching TV at home. Anna's primary concern is receiving inadequate treatment and not achieving disease remission. She also feels misunderstood and lacks family support. This persona reveals several areas where Information and Communication Technology (ICT) interventions, like telemedicine, anxiety and insomnia treatment, drug adherence improvement, and nutritional and lifestyle guidance, could be beneficial. The focus group also outlined the essential features for a prospective mHealth app to meet BMS patients' diverse needs.</div></div><div><h3>CONCLUSION</h3><div>The development of the BMS Blueprint Persona successfully identified patient characteristics and unmet needs, offering valuable insights for creating personalized diagnostic-therapeutic pathways and digital health solutions for BMS.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 3","pages":"Article 102047"},"PeriodicalIF":4.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144263250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ADJUNCTIVE PROBIOTICS SHOW A POSITIVE TREND BUT INCONCLUSIVE CLINICAL BENEFIT IN PERI-IMPLANTITIS MANAGEMENT","authors":"I-TING HSIEH (Reviewers), LING-CHENG MONG, CHIN-WEI WANG, FLAVIA PIRIH","doi":"10.1016/j.jebdp.2025.102166","DOIUrl":"10.1016/j.jebdp.2025.102166","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Lo´ pez-Valverde N, Lo´ pez-Valverde A and Blanco Rueda JA (2024) The role of probiotic therapy on clinical parameters and human immune response in peri‑implant diseases: a systematic review and meta-analysis of randomized clinical studies. Front. Immunol. 15:1371072. <span><span>doi: 10.3389/fimmu.2024.1371072</span><svg><path></path></svg></span></div></div><div><h3>Source of Funding</h3><div>No financial support.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with meta-analysis of data.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 3","pages":"Article 102166"},"PeriodicalIF":4.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144306634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IBRAHIM OGHLI PhD , BIRGITTA HÄGGMAN-HENRIKSON PhD , ERIC L. SCHIFFMAN MS , THOMAS LIST PhD
{"title":"PREDICTORS OF HEALTH-RELATED QUALITY OF LIFE IN TEMPOROMANDIBULAR DISORDER PATIENTS: 8-YEAR COHORT STUDY","authors":"IBRAHIM OGHLI PhD , BIRGITTA HÄGGMAN-HENRIKSON PhD , ERIC L. SCHIFFMAN MS , THOMAS LIST PhD","doi":"10.1016/j.jebdp.2025.102140","DOIUrl":"10.1016/j.jebdp.2025.102140","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to identify baseline factors that predict Health-Related Quality of Life (HRQoL) in patients with TMD 8 years later.</div></div><div><h3>Materials and Methods</h3><div>401 participants (333 women, mean age 45.8 years) from a multicenter cohort were examined using the Diagnostic Criteria for TMD (DC/TMD) and questionnaires. The main outcome was the 12-item Short Form Health Survey (SF-12), a HRQoL measure that provides physical (PCS) and mental (MCS) summaries. Baseline predictors included age, gender, self-reported health, Jaw Functional Limitation Scale (JFLS), pain intensity, pain frequency, and pain duration. Regression analysis with stepwise modeling identified predictive factors.</div></div><div><h3>Results</h3><div>54.3% had painful TMD, 15.7% had nonpainful TMD, and 27.7% were healthy controls. For the painful TMD group, the regression model was significant (<em>R²</em> = .25, <em>F</em> = 4.3, <em>P</em> < .01), with age and favorable general health predicting PCS scores. In the nonpainful TMD group, the model was significant (<em>R²</em> = .58, <em>F</em> = 3.8, <em>P</em> < .01), with JFLS and favorable general health (predicting PCS scores. The MCS model was significant in healthy controls (<em>R<sup>2</sup></em> = .22<em>, F</em> = 1.8<em>, P</em> = .<em>05</em>), with JFLS as only predictor.</div></div><div><h3>Conclusion</h3><div>Predictors of mental HRQoL: JFLS in healthy controls, but no predictors were found in TMD groups. Predictors of physical HRQoL: General health in both TMD groups, JFLS in the nonpainful TMD group, and age in the painful TMD group.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 3","pages":"Article 102140"},"PeriodicalIF":4.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luis Limo , Ronald Espíritu Ayala-Mendívil , Juliana Gabrielle Martins
{"title":"EFFECTIVENESS OF ASSISTED TOOTHBRUSHING ON PRESCHOOLERS’ ORAL HYGIENE: A CAREGIVER-INTERVENTION APPROACH","authors":"Luis Limo , Ronald Espíritu Ayala-Mendívil , Juliana Gabrielle Martins","doi":"10.1016/j.jebdp.2025.102138","DOIUrl":"10.1016/j.jebdp.2025.102138","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the effectiveness of an intervention on caregivers' assisted toothbrushing techniques and oral health maintenance for preschool-aged children, and to determine whether these effects differ by age.</div></div><div><h3>Methods</h3><div>A single group pre/post intervention study was conducted among children aged 3-5 years and their caregivers in Callao, Peru. Eligible caregivers were trained on assisted toothbrushing using large and real-scale typodonts, along with practical demonstrations by a dentist. Additionally, they were instructed on healthy practices and oral health in children. Children's oral hygiene status (OHS) was assessed using the Simplified Oral Hygiene Index (OHI-S) at baseline and three months postintervention. To assess the effectiveness and quantify the magnitude of the difference between the OHI-S before and after the intervention, we used Wilcoxon signed-rank test and the Cliff's Delta test, respectively. Results were stratified by age group to examine potential differences.</div></div><div><h3>Results</h3><div>The sample (<em>n</em> = 210) predominantly comprised 3-year-old Peruvian females, primarily cared for by their mothers, who identified as single mothers who had not previously received instruction in oral hygiene practices. We found improvement in children's OHI-S in most age groups. Specifically, among 3-year-olds, the OHI-S score improved significantly from 'fair' (m = 2.6, ± 0.2, range 2.4-2.8) to 'good' (m = 1.1, ± 0.2, range 0.9-1.3). The intervention showed a moderate effect size (δ = −0.15, 95% CI −0.18, −0.10) in the 3-year-olds and a moderate effect size (δ = −0.05, 95% CI −0.08, −0.01) in the 4-year-olds. No significant improvements were observed in the 5-year-old group.</div></div><div><h3>Conclusion</h3><div>A caregiver-focused intervention significantly improved OHS among preschool-aged children, particularly in younger age groups. Substantial improvements in OHI-S scores were noted for 3- and 4-year-olds, while age-specific factors may have limited efficacy in the 5-year-old group. These findings highlight the importance of early, targeted oral health education for caregivers.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 3","pages":"Article 102138"},"PeriodicalIF":4.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143817260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ACCURACY OF INTRAORAL CAMERA AND SMARTPHONE CAMERA IN TELEDETECTION OF DENTAL CARIES AMONG ADULTS: A DIAGNOSTIC ACCURACY STUDY","authors":"RANA MAHROUS, HALA AMER, WAFAA ESSAM","doi":"10.1016/j.jebdp.2025.102160","DOIUrl":"10.1016/j.jebdp.2025.102160","url":null,"abstract":"<div><h3>Background and Objectives</h3><div>Tele-dentistry combines telecommunications and dentistry to transmit clinical data for remote consultation and treatment planning. It improves dental care access for screening, referrals, and treatment. This study aimed to test the accuracy of intraoral camera and smartphone camera in the diagnosis of cavitated carious lesions among adults in Alexandria, Egypt.</div></div><div><h3>Methods</h3><div>A diagnostic accuracy study was conducted on adults above 18 years old visiting clinics of the Faculty of Dentistry, Alexandria University to compare 2 different tele-dentistry caries detection methods (intraoral camera (C50 Full HD with fluorescence) and smartphone camera (Samsung Galaxy A24) after randomizing the participants into 2 groups. The reference standard was face-to-face examination. The caries diagnosis was based on the International Caries Detection and Assessment System (ICDAS) through clinical examination, intraoral camera videos, and smartphone photos. Sensitivity, specificity, accuracy, positive and negative predictive values were calculated for the 2 methods at tooth and surface levels.</div></div><div><h3>Results</h3><div>The study included 50 adults. The age group (26-40) comprised (46%) of the participants. Both cameras had high specificity and accuracy (>90%). The lowest sensitivity was in the case of detecting cavitated lesions at surface level (intraoral camera = 84.62% and smartphone = 79.52%). The smartphone camera had the lowest precision at both tooth (49.3%) and surface (58.4%) levels.\"</div></div><div><h3>Conclusion</h3><div>The intraoral camera showed higher accuracy than the smartphone camera especially in detecting cavitated carious lesions at surface level. While intraoral cameras are the preferred modality, smartphone cameras provide a more accessible and cost-effective alternative, especially in resource-limited settings. However, their limitations should be acknowledged.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 3","pages":"Article 102160"},"PeriodicalIF":4.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144072666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}