{"title":"EFFECTIVENESS OF CLEAR ORTHODONTIC ALIGNERS IN CORRECTING MALOCCLUSIONS: A SYSTEMATIC REVIEW AND META-ANALYSIS","authors":"MARYAM BANESHI MDS , LUCY O'MALLEY PhD , AHMED EL-ANGBAWI PhD , BADRI THIRUVENKATACHARI PhD","doi":"10.1016/j.jebdp.2024.102081","DOIUrl":"10.1016/j.jebdp.2024.102081","url":null,"abstract":"<div><h3>Objective</h3><div>The purpose of this research was to assess the effectiveness of clear aligners in treating various types of malocclusions when compared to fixed orthodontic appliances.</div></div><div><h3>Methods and Quality</h3><div>The following databases were searched: EMBASE (Ovid), Medline (Ovid), the Cochrane Library, Latin America and the Caribbean Literature on Health Sciences (Lilacs), Web of Science and EBMR review until October 2024. Additionally, Google scholar, PubMed were also searched for completion for including all relevant articles. No restrictions were placed on language or publication date, and only randomized controlled trials (RCTs) were included in this review. Evaluation of the potential for bias in randomized controlled trials (RCTs) was carried out with the use of the revised Cochrane Risk of Bias instrument (ROB tool 2). The primary outcome was the treatment accuracy of clear aligners vs fixed appliances and included orthodontic tooth movement in terms of anteroposterior discrepancy, transverse discrepancy, vertical discrepancy and overjet. The secondary outcomes included the effectiveness of treatment, such as duration of treatment, periodontal health, root resorption and patient satisfaction. Available data was meta-synthesized using Review Manager 5.4.</div></div><div><h3>Results</h3><div>About 21 RCT studies were selected from a total of 600 records and involved 970 participants. All 21 studies included a comparison of the effectiveness of clear aligners vs fixed appliances. About 3 of the studies were assessed to be at high risk of bias, whilst 14 of the studies were assessed to be at unclear risk of bias, and only 1 study was found to be at low risk of bias. Based on the primary outcome, there was no significant difference in the ABO objective grading scores, Little Irregularity Index and PAR scores between the fixed appliances and clear aligner treatments. Meta-analysis was only possible for secondary outcomes. The scores for plaque index (MD = -0.76, 95% CI, -1.14 to - 0.38, <em>P =</em> .00001), gingival index (MD = -0.61, 95% CI, -0.78 to - 0.44, <em>P =</em> .00001) and bleeding index (MD = -0.71, 95% CI, -0.92 to - 0.49, <em>P < .</em>0001) were significantly lower in clear aligners when compared to the fixed appliances. The patients quality of life at 6 months was significantly better for clear aligners compared with fixed appliances (MD = -4.37, 95% CI, -6.93 to -1.80, <em>P</em> < .0001). Clear aligners also appeared to have a better outcome for chairside time, pain and root resorption.</div></div><div><h3>Conclusion</h3><div>The overall quality of evidence from the included studies was low. Both clear aligners and fixed appliances worked well in treating simple malocclusions treated on a nonextraction basis. There was no significant difference in the ABO Objective Grading System, Little Irregularity index and PAR scores between the clear aligner and fixed appliance groups. There was low","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 1","pages":"Article 102081"},"PeriodicalIF":4.1,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LYNDON P ABBOTT , ANKITA SAIKIA , ROBERT P ANTHONAPPA
{"title":"ARTIFICIAL INTELLIGENCE PLATFORMS IN DENTAL CARIES DETECTION: A SYSTEMATIC REVIEW AND META-ANALYSIS","authors":"LYNDON P ABBOTT , ANKITA SAIKIA , ROBERT P ANTHONAPPA","doi":"10.1016/j.jebdp.2024.102077","DOIUrl":"10.1016/j.jebdp.2024.102077","url":null,"abstract":"<div><h3>Objectives</h3><div>To assess Artificial Intelligence (AI) platforms, machine learning methodologies and associated accuracies used in detecting dental caries from clinical images and dental radiographs.</div></div><div><h3>Methods</h3><div>A systematic search of 8 distinct electronic databases: Scopus, Web of Science, MEDLINE, Educational Resources Information Centre, Institute of Electrical and Electronics Engineers Explore, Science Direct, Directory of Open Access Journals and JSTOR, was conducted from January 2000 to March 2024. AI platforms, machine learning methodologies and associated accuracies of studies using AI for dental caries detection were extracted along with essential study characteristics. The quality of included studies was assessed using QUADAS-2 and the CLAIM checklist. Meta-analysis was performed to obtain a quantitative estimate of AI accuracy.</div></div><div><h3>Results</h3><div>Of the 2538 studies identified, 45 met the inclusion criteria and underwent qualitative synthesis. Of the 45 included studies, 33 used dental radiographs, and 12 used clinical images as datasets. A total of 21 different AI platforms were reported. The accuracy ranged from 41.5% to 98.6% across reported AI platforms. A quantitative meta-analysis across 7 studies reported a mean sensitivity of 76% [95% CI (65% - 85%)] and specificity of 91% [(95% CI (86% - 95%)]. The area under the curve (AUC) was 92% [95% CI (89% - 94%)], with high heterogeneity across included studies.</div></div><div><h3>Conclusion</h3><div>Significant variability exists in AI performance for detecting dental caries across different AI platforms. Meta-analysis demonstrates that AI has superior sensitivity and equal specificity of detecting dental caries from clinical images as compared to bitewing radiography. Although AI is promising for dental caries detection, further refinement is necessary to achieve consistent and reliable performance across varying imaging modalities.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 1","pages":"Article 102077"},"PeriodicalIF":4.1,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PATRICIA PEREIRA-LORES , VÍCTOR ALONSO DE LA PEÑA , TANIA GANCEDO-GANCEDO , CAROLINA VILLASENÍN-SÁNCHEZ , ALBA BELLO-CASTRO , BENJAMÍN MARTÍN-BIEDMA , PABLO CASTELO-BAZ
{"title":"A TRIPLE-BLIND RANDOMIZED CLINICAL TRIAL COMPARING THE EFFICACY OF A DESENSITIZING AGENT USED WITH AN AT-HOME BLEACHING TECHNIQUE","authors":"PATRICIA PEREIRA-LORES , VÍCTOR ALONSO DE LA PEÑA , TANIA GANCEDO-GANCEDO , CAROLINA VILLASENÍN-SÁNCHEZ , ALBA BELLO-CASTRO , BENJAMÍN MARTÍN-BIEDMA , PABLO CASTELO-BAZ","doi":"10.1016/j.jebdp.2024.102079","DOIUrl":"10.1016/j.jebdp.2024.102079","url":null,"abstract":"<div><h3>Purpose</h3><div>The aim of this study was to determine whether a sustained-release desensitizing gel containing 3% potassium nitrate and 0.11% fluoride ion reduces the risk of tooth sensitivity without compromising the effectiveness of bleaching treatment.</div></div><div><h3>Methods</h3><div>Thirty-two patients were randomly assigned to 2 experimental groups: desensitizing gel and placebo. The desensitizing gel or placebo was applied for 30 minutes prior to the at-home vital bleaching gel application. A nightguard dental bleaching treatment (NGVB) using a 16% carbamide peroxide gel was performed for 6 hours over a 3-week period. Patients recorded their tooth sensitivity daily using a 5-point Numeric Rating Scale (NRS). Whiteness index measurements were obtained using a dental spectrophotometer on the upper canines (right and left).</div></div><div><h3>Results</h3><div>The overall risk of sensitivity was 37.5% in the desensitizing gel group compared to 87.5% in the placebo group, yielding a relative risk of 0.42 (95% CI 0.22-0.82), showing a statistically significant difference between the groups (<em>P</em> < .05). During the first week, patients in the placebo group exhibited a higher risk of experiencing mild sensitivity. However, no statistically significant differences in sensitivity intensity were observed overall or during the second and third weeks (<em>P</em> > .05). Regarding color change, the mean difference between groups in the first week was 5.25 (-0.22 to 10.71), in the second week 4.25 (-2.56 to 11.02), and in the third week 2.55(-4.11 to 9.22). No statistically significant differences were found between the groups at any time point (<em>P</em> > .05).</div></div><div><h3>Conclusions</h3><div>The use of a sustained-release desensitizing gel containing 3% potassium nitrate and 0.11% fluoride ion for 30 minutes prior to the bleaching agent effectively reduced sensitivity during at-home bleaching procedures. Furthermore, the desensitizing gel did not impact the effectiveness of the at-home bleaching treatment.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 1","pages":"Article 102079"},"PeriodicalIF":4.1,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GISELA CRISTINA VIANNA CAMOLESI , AHMED SAMIR EL KATTAN , JOSÉ LOPEZ-LOPEZ , ANDRÉS BLANCO-CARRIÓN , ABEL GARCÍA-GARCÍA , PILAR GÁNDARA-VILA , MARIO PÉREZ-SAYÁNS
{"title":"PAIN, OEDEMA AND TRISMUS RESPONSES FOLLOWING PHOTOBIOMODULATION THERAPY IMMEDIATELY AFTER LOWER THIRD MOLAR EXTRACTION: RESULTS OF A RANDOMIZED, DOBLE-BLIND AND SPLIT MOUTH CLINICAL TRIAL","authors":"GISELA CRISTINA VIANNA CAMOLESI , AHMED SAMIR EL KATTAN , JOSÉ LOPEZ-LOPEZ , ANDRÉS BLANCO-CARRIÓN , ABEL GARCÍA-GARCÍA , PILAR GÁNDARA-VILA , MARIO PÉREZ-SAYÁNS","doi":"10.1016/j.jebdp.2024.102080","DOIUrl":"10.1016/j.jebdp.2024.102080","url":null,"abstract":"<div><h3>Objectives</h3><div>To assess the impact of photobiomodulation therapy in pain, facial oedema, and trismus mitigation in the postoperative period after lower third molar extractions.</div></div><div><h3>Methods</h3><div>We conducted a comparison between active photobiomodulation and simulated photobiomodulation after both lower third molars extraction in the same patients, within a double-center clinical trial. The role of photobiomodulation was evaluated based on pain, measured using the VAS scale. Oedema and trismus, assessed through millimetric measurements. Additionally, analgesic consumption was monitored during the 7-day's postoperative period. The study adhered to the CONSORT checklist and was registered on the ClinicalTrials (NCT05255731). The Levene test was used to assess precision (α=0.05), and statistical analysis was performed using Jamovi software. Paired t-tests or the Wilcoxon test were employed to analyze the primary and secondary outcomes.</div></div><div><h3>Results</h3><div>The study included 83 patients and 166 randomization units. The study group showed a significant reduction in pain at all evaluation times (<em>P < .</em>01), as well as reductions in facial oedema and trismus on postoperative days 2 and 7 (<em>P < .</em>01). A significant difference in analgesic use was observed on all days, except on the seventh postoperative day.</div></div><div><h3>Conclusion</h3><div>The photobiomodulation protocol, using an 808 nm, 100 mW Ga-Al-As diode laser, applied both intraorally and extraorally in a single 30 seconds (3 Joules/per point) postoperative session, significantly reduced pain, oedema, and trismus following mandibular third molar extraction, particularly on postoperative days 2 and 7.</div></div><div><h3>Clinical Significance</h3><div>Photobiomodulation can be an effective complementary therapy for reducing pain, facial oedema, and trismus in patients after lower third molar extraction.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 1","pages":"Article 102080"},"PeriodicalIF":4.1,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Authors","authors":"","doi":"10.1016/S1532-3382(24)00115-5","DOIUrl":"10.1016/S1532-3382(24)00115-5","url":null,"abstract":"","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"24 4","pages":"Article 102065"},"PeriodicalIF":4.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142758784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Statement of Purpose/Levels of Evidence","authors":"","doi":"10.1016/S1532-3382(24)00113-1","DOIUrl":"10.1016/S1532-3382(24)00113-1","url":null,"abstract":"","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"24 4","pages":"Article 102063"},"PeriodicalIF":4.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142758805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RESIN INFILTRATION MAY HELP MASK ENAMEL WHITE SPOT LESIONS OR FLUOROSIS","authors":"LINDA L. CHENG (REVIEWER)","doi":"10.1016/j.jebdp.2022.101716","DOIUrl":"10.1016/j.jebdp.2022.101716","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div><span><span>Bourouni S, Dritsas K, Kloukos D, Wierichs RJ. Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a </span>systematic review<span> and meta-analysis. Clin Oral Investig. 2021 Aug;25(8):4711-4719. doi:</span></span><span><span>10.1007/s00784-021-03931-7</span><svg><path></path></svg></span>. Epub 2021 Jun 9. PMID: 34106348.</div></div><div><h3>Source of Funding</h3><div>Open Access funding provided by Universit.±t Bern.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with meta-analysis.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"24 4","pages":"Article 101716"},"PeriodicalIF":4.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44889758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Readers","authors":"","doi":"10.1016/S1532-3382(24)00114-3","DOIUrl":"10.1016/S1532-3382(24)00114-3","url":null,"abstract":"","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"24 4","pages":"Article 102064"},"PeriodicalIF":4.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142758783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FILIPE COLOMBO VITALI PhD , PAULA AKEMI ALBUQUERQUE KOMINAMI MS , ANA CRISTINA ANDRADA DMSc , ELIANA MITSUE TAKESHITA PhD , CARLA MASSIGNAN PhD
{"title":"IMPACT OF PULPECTOMY VERSUS EXTRACTION OF PRIMARY TEETH ON PATIENT-CENTERED OUTCOMES: A SYSTEMATIC REVIEW OF CLINICAL STUDIES","authors":"FILIPE COLOMBO VITALI PhD , PAULA AKEMI ALBUQUERQUE KOMINAMI MS , ANA CRISTINA ANDRADA DMSc , ELIANA MITSUE TAKESHITA PhD , CARLA MASSIGNAN PhD","doi":"10.1016/j.jebdp.2024.102072","DOIUrl":"10.1016/j.jebdp.2024.102072","url":null,"abstract":"<div><h3>Objectives</h3><div>Although pulpectomy is recommended as the choice treatment for primary teeth with pulpal involvement, some clinicians and parents consider tooth extraction a viable option. This systematic review aimed to assess the impact of pulpectomy versus extraction of primary teeth on patient-centered outcomes.</div></div><div><h3>Methods</h3><div>Seven electronic databases and grey literature were searched on April 05, 2024. Two independent reviewers selected clinical trials comparing the impact of pulpectomy versus extraction of primary teeth on patient-centered outcomes. Studies not directly comparing pulpectomy versus tooth extraction were excluded. Critical data were summarized following the Synthesis Without Meta-analysis guideline. The risk of bias was assessed using the Version 2 Cochrane risk-of-bias tool for randomized clinical trials and the Risk Of Bias In Nonrandomized Studies of Interventions tool for nonrandomized clinical trials. The certainty of evidence was assessed using the GRADE approach.</div></div><div><h3>Results</h3><div>A total of 1228 studies were retrieved in the search. After the screening process, two studies were included. The outcomes evaluated were oral health-related quality of life (OHRQoL), dental anxiety, postoperative pain, and behavior. Qualitative synthesis indicated that children treated with pulpectomy exhibited improved OHRQoL and lower dental anxiety than those treated with tooth extraction. The treatment modality did not influence behavior and postoperative pain. Included studies present potential bias in specific domains. The certainty of evidence was low.</div></div><div><h3>Conclusion</h3><div>Pulpectomy demonstrated superior patient-centered outcomes, suggesting that it is a more favorable choice for treating primary teeth than tooth extraction.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 1","pages":"Article 102072"},"PeriodicalIF":4.1,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}