{"title":"IN SIMPLER MALOCCLUSION TYPES, CLEAR ALIGNERS COULD BE CONSIDERED AFTER CAREFUL CONSIDERATION OF OCCLUSAL AND ADHERENCE FACTORS","authors":"CARLOS FLORES-MIR DSc (Reviewer)","doi":"10.1016/j.jebdp.2025.102197","DOIUrl":"10.1016/j.jebdp.2025.102197","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Baneshi et al. Effectiveness of clear orthodontic aligners in correcting maloclusions: A systematic review and meta-analysis. J Evid Base Dent Pract 2025: 102081. Doi: <span><span>10.1016/j.jebdp.224.102081</span><svg><path></path></svg></span>.</div></div><div><h3>Source of Funding</h3><div>Not reported.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with meta-analysis of data.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 4","pages":"Article 102197"},"PeriodicalIF":4.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"GTR USING CALCIUM PHOSPHATE GRAFTS MAY ENHANCE CLINICAL ATTACHMENT GAIN IN INTRABONY DEFECTS COMPARED TO FLAP DEBRIDEMENT","authors":"ROBERT M. EBER (Reviewer)","doi":"10.1016/j.jebdp.2025.102196","DOIUrl":"10.1016/j.jebdp.2025.102196","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Calcium phosphate grafts combined with guided tissue regeneration in the treatment of periodontal bony defects- a systematic review and meta-analysis. Kouhi M, Yousefi S, Sajadi-Javan SS, Sadeghi E, Savabi O, Shirani M. J Evid Base Dent Pract 2024; 24(4):1-14</div></div><div><h3>Source of Funding</h3><div>Other: Vice-Chancellery for Research and Technology of Isfahan University of Medical Sciences [grant number: 140181].</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with meta-analysis of data</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 4","pages":"Article 102196"},"PeriodicalIF":4.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
KORINA YUN-FAN LU , JENNIFER L. GIBBS , CHENG-YU WU , MARKUS B. BLATZ , XUEHAO MA , MIN-WEN FU , KEVIN SHENG-KAI MA
{"title":"EFFICACY OF BIODENTINE VERSUS MINERAL TRIOXIDE AGGREGATE IN PULPOTOMY FOR PRIMARY TEETH: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS","authors":"KORINA YUN-FAN LU , JENNIFER L. GIBBS , CHENG-YU WU , MARKUS B. BLATZ , XUEHAO MA , MIN-WEN FU , KEVIN SHENG-KAI MA","doi":"10.1016/j.jebdp.2025.102191","DOIUrl":"10.1016/j.jebdp.2025.102191","url":null,"abstract":"<div><h3>Background</h3><div>Mineral trioxide aggregate (MTA) and Biodentine, introduced in the 1990s and 2010, are routinely used in primary teeth pulpotomy, yet their relative success remains unclear.</div></div><div><h3>Objectives</h3><div>This paper aims to compare Biodentine and MTA efficacy in primary teeth pulpotomy over a 6 to 24-month follow-up, assessing clinical, radiographic, and endodontic outcomes.</div></div><div><h3>Materials and Methods</h3><div>Randomized controlled trials (RCTs) published from March 2010 to March 2025 comparing the efficacy of Biodentine and MTA in primary teeth pulpotomy with ≥6-month follow-up were included. Their efficacy was determined by clinical and radiographic success rates, as well as 2 endodontic outcomes of root resorption and pulp canal obliteration (PCO). A bivariate and random-effect meta-analysis determined the pooled risk ratios (RRs) of the outcomes.</div></div><div><h3>Results</h3><div>Eleven RCTs comprising 649 patients and 706 primary teeth were included. Clinical success rates were comparable between Biodentine and MTA at 6 months (RR = 1.00; 95% CI: 0.98-1.02), 12 months (RR = 1.01; 95% CI: 0.97-1.04), 18 months (RR = 0.99; 95% CI: 0.95-1.04), and 24 months (RR = 1.00; 95% CI: 0.94-1.07), with no observed heterogeneity (I² = 0%). Radiographic success rates also showed no significant differences at 6 months (RR = 0.99; 95% CI: 0.97-1.02), 12 months (RR = 1.00; 95% CI: 0.96-1.03), 18 months (RR = 1.01; 95% CI: 0.94-1.09), and 24 months (RR = 1.01; 95% CI: 0.94-1.08). Root resorption and pulp canal obliteration occurred at comparable rates across over 6, 12, and ≥18 months of follow-ups.</div></div><div><h3>Conclusion</h3><div>Biodentine and MTA exerted comparable success rates in primary teeth pulpotomy at follow-ups of up to 2 years.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 4","pages":"Article 102191"},"PeriodicalIF":4.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145265002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-Term Mandibular Advancement Devices for Obstructive Sleep Apnea may Result in Progressive Dental Changes with Minimal Skeletal Effects","authors":"NARAYAN H. GANDEDKAR (Reviewer)","doi":"10.1016/j.jebdp.2025.102202","DOIUrl":"10.1016/j.jebdp.2025.102202","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Yu M, Ma Y, Gong X, Gao X. Dental and skeletal changes of long-term use of mandibular advancement devices for the treatment of adult obstructive sleep apnea: a systematic review and meta-analysis. <em>J Evid Based Dent Pract.</em> 2024;24(3):1-17. <span><span>doi:10.1016/j.jebdp.2024.101991</span><svg><path></path></svg></span>.</div></div><div><h3>Source of Funding</h3><div>Clinical Research Foundation of Peking University School and Hospital of Stomatology (PKUSS-2023CRF106).</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with meta-analysis.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 4","pages":"Article 102202"},"PeriodicalIF":4.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PULPECTOMY MAY PROVIDE BETTER PATIENT-CENTERED OUTCOMES THAN EXTRACTION OF PULPALLY INVOLVED PRIMARY TEETH","authors":"CHRIS DEERY (Reviewer)","doi":"10.1016/j.jebdp.2025.102189","DOIUrl":"10.1016/j.jebdp.2025.102189","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Impact Of Pulpectomy Versus Extraction Of Primary Teeth On Patient-Centered Outcomes: A Systematic Review Of Clinical Studies. Vitali FC, Kominami PAA, Andrada AC, Takeshita EM, Massignan C. J Evid Base Dent Pract 2025: [102072] <span><span>https://doi.org/10.1016/j.jebdp.2024.102072</span><svg><path></path></svg></span></div></div><div><h3>Source of Funding</h3><div>Government: <span>Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina (FAPESC)</span> - Edital 20/2024 - Brazil, grant number <span><span>001</span></span>.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 4","pages":"Article 102189"},"PeriodicalIF":4.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144912894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"AI MAY SHOW COMPARABLE DIAGNOSTIC ACCURACY TO EXPERTS IN ORAL CANCER DETECTION, BUT EVIDENCE REMAINS LIMITED AND OF LOW CERTAINTY","authors":"OMER WALEED MAJID (Reviewer)","doi":"10.1016/j.jebdp.2025.102199","DOIUrl":"10.1016/j.jebdp.2025.102199","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Nieri M, Serni L, Clauser T, Paoletti C, Franchi L. Diagnosis of Oral Cancer With Deep Learning. A Comparative Test Accuracy Systematic Review. Oral Dis. 2025 Mar 31. <span><span>doi:10.1111/odi.15330</span><svg><path></path></svg></span>. Epub ahead of print.</div></div><div><h3>Source of Funding</h3><div>Not reported.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with network meta-analysis.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 4","pages":"Article 102199"},"PeriodicalIF":4.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LAILA AL DEHAILAN (Reviewers), NAIF N. ABOGAZALAH, E. ANGELES MARTINEZ-MIER
{"title":"HYDROPHILIC SEALANTS MAY IMPROVE SHORT-TERM RETENTION BUT SHOW SIMILAR CARIES PREVENTION TO HYDROPHOBIC SEALANTS","authors":"LAILA AL DEHAILAN (Reviewers), NAIF N. ABOGAZALAH, E. ANGELES MARTINEZ-MIER","doi":"10.1016/j.jebdp.2025.102200","DOIUrl":"10.1016/j.jebdp.2025.102200","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Comparative evaluation of retention and caries preventive effect of hydrophilic and hydrophobic pit and fissure sealants: a systematic review and meta-analysis. Jadhav Sachin Kumar, Zainab Akram, Pg Naveen Kumar, Mahesh R. Khairnar, Andneha Shukla. J Evid Base Dent Pract 2025: [102085]</div></div><div><h3>Source of Funding</h3><div>Information not available.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with meta-analysis of data.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 4","pages":"Article 102200"},"PeriodicalIF":4.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145109681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CATARINA NUNES , BEATRIZ ORNELAS , CARLOS MIGUEL MARTO , ANABELA PAULA , MAFALDA LARANJO , CATARINA MESTRE , RAQUEL TRAVASSOS , INÊS FRANCISCO , FRANCISCO VALE
{"title":"CYTOTOXICITY OF ORTHODONTICS ALIGNERS: AN UMBRELLA REVIEW","authors":"CATARINA NUNES , BEATRIZ ORNELAS , CARLOS MIGUEL MARTO , ANABELA PAULA , MAFALDA LARANJO , CATARINA MESTRE , RAQUEL TRAVASSOS , INÊS FRANCISCO , FRANCISCO VALE","doi":"10.1016/j.jebdp.2025.102168","DOIUrl":"10.1016/j.jebdp.2025.102168","url":null,"abstract":"<div><h3>Objective</h3><div>This umbrella review aims to determine if clear aligners promote cytotoxic and estrogenic effects.</div></div><div><h3>Methodology</h3><div>The review was conducted in conformity with the PRISMA statement. A systematic search was carried out in March of 2025 in 5 databases (Medline through PubMed, Web of Science (all databases), Cochrane Library, Embase, and Epistemonikos). All systematic reviews (SRs) that reported the cytotoxicity and/or estrogenicity of orthodontic aligners were included. The quality of the included studies was evaluated using AMSTAR-2 and the degree of overlap was analysed using Corrected Covered Area (CCA).</div></div><div><h3>Results</h3><div>The literature search resulted in 394 articles. Screening by title and abstract, resulted in 13 articles for full reading, and 4 articles were included in the umbrella review. According to the AMSTAR-2, all reviews were of low quality. The degree of overlap among SRs is high.</div></div><div><h3>Discussion</h3><div>The included SRs indicate that aligners do not have significant estrogenic/cytotoxic capacity and, even in cases of bisphenol A (BPA) leaching, this occurs at levels well below what is considered toxic. The low quality, high risk of bias, considerable overlap, and significant heterogeneity among the included studies impacts the obtained results.</div></div><div><h3>Conclusion</h3><div>It is not possible to affirm or refute the presence of estrogenic or cytotoxic effects or the leaching of monomers such as BPA. In the future, it is recommended that studies adopt a more detailed and prolonged analysis of BPA leaching and it is necessary to carry out clinical studies that evaluate the safety and biocompatibility of orthodontic aligners.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 3","pages":"Article 102168"},"PeriodicalIF":4.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144534618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MARYAM EMAMI , MEHDI AZIZMOHAMMAD LOOHA , KEITH DA-SILVA , MOHAMMADJAVAD SHIRANI
{"title":"EFFICACY OF PHOTOBIOMODULATION THERAPY ON PAIN PERCEPTION DURING LOCAL ANESTHESIA IN CHILDREN: A SYSTEMATIC REVIEW AND META-ANALYSIS","authors":"MARYAM EMAMI , MEHDI AZIZMOHAMMAD LOOHA , KEITH DA-SILVA , MOHAMMADJAVAD SHIRANI","doi":"10.1016/j.jebdp.2025.102143","DOIUrl":"10.1016/j.jebdp.2025.102143","url":null,"abstract":"<div><h3>Objective</h3><div>This systematic review and meta-analysis is the first to evaluate the impact of photobiomodulation therapy (PBMT) on objective and physiological measures of local anesthesia injection pain in children aged 3-12.</div></div><div><h3>Methods</h3><div>This review follows the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA) guidelines and is registered in the International Prospective Register of Systematic Reviews (PROSPERO) under the registration number CRD42024549936. A systematic search was conducted in Embase, PubMed, and the Cochrane Library to locate relevant Randomized Clinical Trials (RCTs) between January 2000 to September 2024. Study screening, data extraction, risk of bias evaluation, and certainty of evidence grading were performed independently by 2 reviewers. Meta-analyses focused on the pain assessment using following measures: Wong-Baker Faces Pain Rating Scale (PRS), Sound, Eye, and Motor Scale (SEM), Face, Legs, Activity, Cry, Consolability Scale (FLACC), and heart rate (HR). Sensitivity analyses were conducted using a leave-one-study-out approach to assess the robustness of the findings, while publication bias and heterogeneity were evaluated through established statistical methods.</div></div><div><h3>Results</h3><div>Out of 1322 identified studies, 7 RCTs met inclusion criteria. PBMT significantly reduced pain, with moderate certainty, as measured by the objective FLACC scale (SMD = −0.41, 95% CI: −0.72, −0.09, <em>P</em> = .011) and the physiological HR method (SMD = −0.50, 95% CI: −0.86, −0.14, <em>P</em> = .006), demonstrating moderate and no heterogeneity, respectively. However, no statistically significant effect was observed on subjective measures using the PRS (SMD = −0.66, 95% CI: −1.63, 0.32, <em>P</em> = .185) and SEM (SMD = 0.18, 95% CI: −1.09, 1.45, <em>P</em> = .780) scales. Five studies had low risk of bias, and GRADE analysis indicated very low to moderate certainty. Funnel plots showed minimal publication bias, except for slight asymmetry in PRS.</div></div><div><h3>Conclusions</h3><div>PBMT demonstrates potential as a nonpharmacological method to reduce injection pain in children, as reflected in FLACC and HR outcomes. However, no significant effect of PBMT was observed on the SEM scale. Further research is needed to clarify its impact on subjective pain measures (PRS) and to optimize PBMT protocols.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 3","pages":"Article 102143"},"PeriodicalIF":4.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}