{"title":"Understanding eating behaviors in obesity: a DEBQ-based analysis of clinical and demographic factors.","authors":"Yasemin Koçyiğit, Hatice Ayça Kaloğlu","doi":"10.1186/s40337-026-01701-y","DOIUrl":"10.1186/s40337-026-01701-y","url":null,"abstract":"<p><strong>Background: </strong>Obesity is a multifactorial chronic disease influenced by metabolic, genetic, behavioral, and psychosocial factors. This study aimed to assess eating behaviors in treatment-seeking individuals with obesity using the Dutch Eating Behavior Questionnaire (DEBQ) and to explore the associations of its emotional, external, and restrained eating subscales with clinical and sociodemographic characteristics.</p><p><strong>Methods: </strong>This study included 220 individuals with obesity who were followed at the Etlik City Hospital Obesity Center. Psychiatric diagnoses were assessed using the Structured Clinical Interview for DSM-5 Disorders (SCID-5). Data were collected through face-to-face interviews using a sociodemographic form and the DEBQ. Regression analyses were conducted as exploratory, hypothesis-generating models to identify variables associated with DEBQ subscale scores, without implying causal relationships.</p><p><strong>Results: </strong>Emotional eating was positively associated with years of education, depression, obsessive-compulsive disorder (OCD), and the presence of an eating disorder-related condition. The strongest association was observed for the presence of an eating disorder-related condition, which may partly reflect conceptual and measurement overlap with the emotional eating construct assessed by the DEBQ. Restrained eating was positively associated with duration of obesity and negatively associated with the presence of an eating disorder-related condition. External eating was positively associated with years of education and the presence of an eating disorder-related condition.</p><p><strong>Conclusion: </strong>Eating behaviors among treatment-seeking individuals with obesity appear heterogeneous and are associated with both psychiatric and sociodemographic factors. In particular, emotional eating was linked to depression, OCD, and the presence of an eating disorder-related condition; however, associations involving eating disorder-related condition should be interpreted cautiously due to potential construct overlap. These findings underscore the importance of assessing psychiatric comorbidities and eating behavior patterns in the individualized management of obesity.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2026-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13621460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148392246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The intersection of ADHD and anorexia: a qualitative exploration of how ADHD shapes eating disorder experiences.","authors":"Romi Goldschlager, Kurea Adrian, Eva Gregertsen, Katia Manariti, Eveline Mu, Jayashri Kulkarni","doi":"10.1186/s40337-026-01682-y","DOIUrl":"https://doi.org/10.1186/s40337-026-01682-y","url":null,"abstract":"<p><strong>Introduction: </strong>Anorexia nervosa (AN) is an eating disorder (ED) characterised by restrictions in energy intake, intense fear of weight gain and distorted body image. AN may coexist with attention-deficit/hyperactivity disorder (ADHD), a neurotype characterised by differences in attention and/or impulsivity and hyperactivity. Despite increasing recognition of neurodivergence in EDs, the co-occurrence of ADHD and AN remains markedly under-researched. Clarifying their interaction will improve diagnostic accuracy, tailor treatments, and ultimately enhance outcomes for individuals living with both neurobiological profiles. The objective of this study is to investigate how features of ADHD and AN influence the lived experience of adults with both profiles.</p><p><strong>Methods: </strong>Fifteen adults with co-occurring ADHD and AN participated in semi-structured interviews exploring how features of each profile shaped their experience. Qualitative data was analysed using Braun and Clarke's reflexive thematic analysis.</p><p><strong>Results: </strong>Four themes were developed. The interaction and overlap of features of ADHD and AN as well as challenges teasing the two apart was central for participants. ADHD and AN features were intentionally and unintentionally instrumentalised, perpetuating the co-occurring profile and making participants' experiences of co-occurring ADHD-AN challenging to navigate. Participants experienced profound shame resulting from ADHD-related systemic factors which in some cases appeared to predispose them to the development of AN. Overall, participants emphasised the importance of making ADHD-AN visible, highlighting the need for both this research and clinical attunement and dexterity to support individual patient experiences.</p><p><strong>Conclusions: </strong>To our knowledge, this is the first qualitative study providing evidence of how the features of ADHD and AN interact. The findings emphasise shared challenges in living with the co-occurring profiles, highlighting the need for increased understanding and greater recognition of ADHD-AN.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148383077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cystatin-C outperforms creatinine for estimating renal function in adolescents with anorexia nervosa: cross-sectional method-comparison study.","authors":"Marine Bouron, Anne-Laure Lapeyraque, Olivier Jamoulle, Danielle Taddeo, Chantal Stheneur","doi":"10.1186/s40337-026-01700-z","DOIUrl":"10.1186/s40337-026-01700-z","url":null,"abstract":"<p><strong>Background: </strong>Individuals with anorexia nervosa are at increased risk of renal impairment, but assessing renal function in this population remains challenging. Cystatin-C, which is less affected by nutritional status than creatinine, may provide a more reliable biomarker. However, equations based on cystatin-C (CKiD‑U25, EKFC, and CKD-EPI) have not yet been evaluated against isotopic scintigraphy in individuals with anorexia nervosa.</p><p><strong>Objective: </strong>This study aimed to compare the performance of creatinine-based and cystatin-C-based equations (CKiD-U25, EKFC, CKD-EPI) against 99mTc-DTPA renal scintigraphy as the reference standard in adolescents with restrictive anorexia nervosa.</p><p><strong>Methods: </strong>Glomerular filtration rate was measured using renal scintigraphy and estimated with creatinine-based and cystatin-C-based equations. Serum cystatin-C and creatinine were measured at hospital admission (day 0), whereas renal scintigraphy was performed as soon as feasible after admission (mean of 5 days), in adolescents with restrictive anorexia nervosa. Correlation coefficients, mean bias, root mean square error, and Bland-Altman plots were assessed.</p><p><strong>Results: </strong>Across all equations, cystatin-C-based formulas consistently outperformed creatinine-based ones in terms of correlation, bias, and precision. The CKiD-U25 using cystatin-C equation showed the strongest correlation with renal scintigraphy (r = 0.77; bias = - 11.5 mL/min/1.73 m<sup>2</sup>).</p><p><strong>Conclusions: </strong>At admission for restrictive anorexia nervosa, cystatin-C-based equations, particularly the CKiD-U25, demonstrate superior agreement with renal scintigraphy compared to creatinine-based equations, making cystatin-C-based equations more reliable in this context.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13602572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148383005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lea Pueschel, Stefanie Claire Fuhrberg, Leonie Kuhn, Josephine Conrad, Marina Florea, Navid Pueschel, Linda Schemann, Yilmaz Rohat Kala, Konstantina Atanasova, Laura-Louise Knoedler, Wolfgang Reindl, Eva Lina Wilke, Moritz Middelhoff, Anne Kerstin Thomann, Miriam Wiestler
{"title":"Sex-specific patterns of avoidant and restrictive eating in inflammatory bowel disease: validation of the German version of the Nine Item Avoidant/Restrictive Food Intake disorder screen (NIAS).","authors":"Lea Pueschel, Stefanie Claire Fuhrberg, Leonie Kuhn, Josephine Conrad, Marina Florea, Navid Pueschel, Linda Schemann, Yilmaz Rohat Kala, Konstantina Atanasova, Laura-Louise Knoedler, Wolfgang Reindl, Eva Lina Wilke, Moritz Middelhoff, Anne Kerstin Thomann, Miriam Wiestler","doi":"10.1186/s40337-026-01702-x","DOIUrl":"10.1186/s40337-026-01702-x","url":null,"abstract":"<p><strong>Background: </strong>Avoidant/Restrictive Food Intake Disorder (ARFID) is a possible comorbidity in patients with Inflammatory Bowel Disease (IBD). Early detection and intervention are crucial to prevent malnutrition and related complications. However, ARFID often remains undiagnosed due to its subtle presentation.</p><p><strong>Methods: </strong>This multicenter study enrolled 235 patients with IBD at German tertiary referral centers between March and September 2025. The Nine Item Avoidant/Restrictive Food Intake disorder screen (NIAS), a screening tool for ARFID, was translated into German and administered at baseline and follow-up. The validity and reliability of the NIAS German were assessed via hypothesis testing and Cronbach's α coefficient.</p><p><strong>Results: </strong>The NIAS German demonstrated excellent internal consistency (Cronbach's α = 0.810) and test-retest reliability (p < 0.001). A significant correlation was found between the initial and follow-up NIAS scores for all items (p < 0.001). Furthermore, the intraclass correlation coefficient of 0.896 (95% CI: 0.846-0.931) confirmed the reliability of the German questionnaire version. Notably, women with IBD scored significantly higher on the NIAS and its subscales, indicating a greater likelihood and severity of ARFID symptoms, as screened by the NIAS (Md [IQR]: women = 13 [7-17]; men = 10 [6-15]; p = 0.007).</p><p><strong>Conclusions: </strong>The German version of the NIAS demonstrated good reliability and initial evidence supporting its use as a screening instrument in German-speaking men and women with IBD. The findings of this study highlight the importance of sex-specific assessment and suggest that IBD women may be at higher risk of developing ARFID. Early detection and targeted interventions are essential to prevent malnutrition and related complications in this vulnerable population.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13339524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148383041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From establishment to network consolidation: Registrant engagement and collaborative development in the international Consortium for Research in Eating Disorders (CoRe-ED).","authors":"Gemma Sharp, Hao Hu, Peter Wigley","doi":"10.1186/s40337-026-01696-6","DOIUrl":"10.1186/s40337-026-01696-6","url":null,"abstract":"<p><strong>Background: </strong>Eating disorders are a global health concern, yet research in this field has historically been underfunded and sometimes perceived as \"niche\". To attempt to address these challenges, the international charity Consortium for Research in Eating Disorders (CoRe-ED) was launched in September 2024. CoRe-ED aims to promote innovations in eating disorders research by empowering all voices and supporting the development of new therapies. The present study examined the characteristics of individuals who joined CoRe-ED over the first ~ 15 months, their engagement with consortium initiatives and their expected benefits and experiences.</p><p><strong>Methods: </strong>Between 25 September 2024 and 31 December 2025, CoRe-ED registrants completed an online registration form and consented to the use of deidentified, aggregated data for research. Data were analysed for registrant characteristics, including primary country of residence and role(s) (e.g., researcher, health professional, lived experience), and for perceived expectations and experiences, using inductive thematic analysis. Survey feedback from ten CoRe-ED events, engagement with collaborative CoRe-ED initiatives, and an overarching survey capturing overall registrant experiences were also analysed.</p><p><strong>Results: </strong>A total of 960 individuals from 37 countries across five continents registered with CoRe-ED, representing researchers, health professionals, individuals with lived experience, advocates, not-for-profit representatives and industry professionals. Registrants' expectations included networking and community building, research contribution and collaboration, learning and professional development, advocacy, facilitation of innovation, integration of lived experience into research, global collaboration and mentorship. CoRe-ED also implemented a structured \"Next Big Research Idea\" initiative, which involved 18 internationally distributed multidisciplinary teams across 20 countries in collaborative research proposal development. Event-specific and overall feedback indicated high satisfaction with CoRe-ED activities, particularly valuing the diversity of presenters, global perspectives, inclusive environment and opportunities to learn and connect.</p><p><strong>Conclusions: </strong>Over the first ~ 15 months, CoRe-ED engaged a diverse, international registrant group and developed activities consistent with early registrant expectations. The consortium implemented initiatives intended to support cross-disciplinary research collaboration, knowledge exchange and innovation, while expanding international representation. Future research should examine longer-term experiences, including impacts on research outputs, mentorship, co-design and policy translation, to better understand how the consortium evolves in response to the needs of its international community.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13599308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148377279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A bibliometric analysis of eating disorders in adolescents.","authors":"Gökhan Dege, Miray Deliktaş, Nursel Gül, Esra Yildirim, Aylin Yildirim, Metin Yildiz","doi":"10.1186/s40337-026-01695-7","DOIUrl":"10.1186/s40337-026-01695-7","url":null,"abstract":"<p><strong>Aim: </strong>The study aims to conduct a bibliometric analysis of eating disorders in adolescents.</p><p><strong>Methods: </strong>In this study, the terms TS=(\"adolescent\" OR \"youth\" OR \"teenagers\" OR \"adolescence\") AND (eating disorder OR anorexia nervosa OR bulimia nervosa) were systematically searched in the Web of Science database. The R bibliometric package was used to analyze the search results. This study systematically maps the field for the period 2016-2025 by employing co-authorship, bibliographic coupling, keyword co-occurrence, and citation analyses to identify leading contributors, publication outlets, countries, influential works, and thematic structures.</p><p><strong>Results: </strong>The analysis covered the period from 2016 to 2025, with publication numbers fluctuating over the years. The number of publications peaked in 2021. Research activities were concentrated in the United States, Germany, Australia, and Canada. The leading journals included the International Journal of Eating Disorders and the Journal of Eating Disorders, followed by Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity, European Eating Disorders Review, and Eating Behaviors. Frequently used keywords included anorexia nervosa, eating disorders, adolescents, and bulimia nervosa.</p><p><strong>Conclusion: </strong>This bibliometric analysis demonstrates that the literature on eating disorders in adolescents has evolved over time in response to global events, research funding, and changing clinical priorities. In particular, publication output increased markedly during the COVID-19 pandemic period, with the most prolific authors focusing on key topics such as family-based treatment and eating disorders in males. Countries including the United States, Germany, Australia, Canada, and the United Kingdom emerged as leading contributors in terms of research productivity. Additionally, publications were largely concentrated in a limited number of core journals with high impact factors.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13599315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148370196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noah Lensch, Elias Fischer, Günter Reich, Thomas Meyer
{"title":"Intrafamilial concordance in perceived family dysfunction among children with eating disorders and their parents.","authors":"Noah Lensch, Elias Fischer, Günter Reich, Thomas Meyer","doi":"10.1186/s40337-026-01663-1","DOIUrl":"10.1186/s40337-026-01663-1","url":null,"abstract":"<p><strong>Background: </strong>Studies on eating disorders (EDs) examining differences in the perception of family structures among patients with anorexia nervosa (AN) and bulimia nervosa (BN) are rare. In particular, intrafamilial differences in the assessment of family functioning and their potential therapeutical consequences remain underrepresented in current research.</p><p><strong>Methods: </strong>Our sample comprised 540 patients diagnosed with ED and their parents, including 184 mothers and 156 fathers, who participated in the FamFINED study. Using the total score of the General Family Questionnaire (Allgemeiner Familienbogen; FBa), we compared the perceptions of family functioning among patients diagnosed with AN (n = 269) or BN (n = 271) including their respective parents.</p><p><strong>Results: </strong>Among the study cohort, significant correlations were found between the total FBa scores of patients and their mothers (n = 180, r = 0.186, p = 0.012) as well as between patients and fathers (n = 155, r = 0.440, p < 0.001). Furthermore, the total FBa score was significantly linked to the difference to the desired weight (n = 449, r = 0.174, p < 0.001). Individuals with BN perceived greater family dysfunction, as indicated by a significantly higher total FBa score, compared to those with AN (59.37 ± 6.97 vs. 57.77 ± 8.28, p = 0.015). Similarly, mothers and fathers of AN patients reported lower total FBa scores than the parents in the BN group, but these differences did not reach statistical significance. Multiple linear regression analysis adjusted for patient age, body-mass index (BMI), presence of siblings, and highest educational attainment confirmed the significant association between the patient´s total FBa score and ED diagnosis (β = 1.92, 95%-confidence interval = 0.098-3.735, p = 0.039).</p><p><strong>Conclusion: </strong>The study confirms that patients with BN perceive their families as significantly more dysfunctional compared to those with AN. In addition, our data indicate that, in families affected with ED, the difference between the desired and the actual weight significantly correlates with the total FBa score of the patients. Furthermore, we found that ED patients reporting higher total FBa scores also had parents who perceive their family structure as less functional.</p><p><strong>Clinical trial registration: </strong>ClinicalTrials.gov Identifier: NCT05339165.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13371231/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148363126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
James Downs, Anna Carnegie, Mollie Twitchell, Bella Reed, David Morris, David Viljoen, Samuel Chawner, Agnes Ayton
{"title":"Do new labels solve old problems? Conceptual, ethical, and clinical challenges of constructing restrictive eating behaviours as \"self-harm\".","authors":"James Downs, Anna Carnegie, Mollie Twitchell, Bella Reed, David Morris, David Viljoen, Samuel Chawner, Agnes Ayton","doi":"10.1186/s40337-026-01654-2","DOIUrl":"10.1186/s40337-026-01654-2","url":null,"abstract":"<p><p>The concept of \"Restrictive Intake Self-Harm\" (\"RISH\") has recently been introduced to conceptualise divergent and/or complex presentations of restrictive eating behaviours as a form of self-harm, rather than symptoms of an eating disorder. Whilst this may represent a well-intentioned response to poorly met clinical needs, it also raises significant conceptual, ethical, and clinical concerns. This paper, written by authors with clinical, academic, and lived experience, situates \"RISH\" within a broader history of premature classificatory expansion in eating disorders, whereby new terminology has been introduced with insufficient empirical support and a lack of substantive coproduction with people with lived experience. Our analysis highlights the unintended consequences of this approach and how conflating restriction with self-injurious behaviour risks conceptual ambiguity, diagnostic misclassification, and the diversion of patients away from specialist services and evidence-based treatments that may benefit them. We advocate an empirical, data-driven approach to understanding the heterogeneous nature of restrictive eating and its diverse biological, psychological, social, and cultural drivers, across diagnoses. In clinical practice, greater skill in differential diagnosis and collaborative, individualised formulation is needed, alongside reform of service design to facilitate more integrated care. Vitally, terminology and care pathways for disordered eating need to be meaningfully coproduced with the people who need them, recognising the plurality and legitimacy of experiential knowledge as central to creating more inclusive and attuned care.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"14 1","pages":""},"PeriodicalIF":5.7,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13317043/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cliona Brennan, Ellen McAdams, Elena Pears, Paula Herrera-Gener, Julian Baudinet, Mima Simic
{"title":"The intensive outreach programme for child and adolescent eating disorders: an uncontrolled case series of clinical characteristics and treatment outcomes.","authors":"Cliona Brennan, Ellen McAdams, Elena Pears, Paula Herrera-Gener, Julian Baudinet, Mima Simic","doi":"10.1186/s40337-026-01664-0","DOIUrl":"10.1186/s40337-026-01664-0","url":null,"abstract":"<p><strong>Introduction: </strong>Despite growing interest, empirical evidence remains limited for the efficacy of intensive outpatient programmes (IOPs) for eating disorders (EDs), particularly outside the USA. No prior studies have examined the delivery or effectiveness of IOPs for children and young people in the UK. This study addresses this gap by presenting pilot data from a UK-based community IOP embedded within an existing child and adolescent ED service.</p><p><strong>Methods: </strong>We conducted a prospective cohort study of young people aged 12-18 years referred to the IOP at the Maudsley Centre for Child and Adolescent Eating Disorders between February 2024 and August 2025. Eligible participants had a diagnosis of an ED according to ICD-11 criteria, or disordered eating requiring acute admission, and completed the IOP treatment. Data were collected on referral pathways, demographic and clinical characteristics, treatment course, and outcomes, including change in weight and self-reported ED/mental health symptoms.</p><p><strong>Results: </strong>During the recruitment period the IOP served a heterogeneous cohort of 68 young people with high rates of psychiatric and neurodevelopmental comorbidity. Treatment delivery included outreach on paediatric wards, intensified outpatient treatment, and consultation with wider care networks. Mean duration of the IOP was 24 days (SD = 10.7). Most participants demonstrated improved weight trajectory (mean weight gain = 4.5% mBMI, SD = 6.8, p < 0.001). ED symptom psychopathology did not significantly improve over the short IOP duration.</p><p><strong>Conclusion: </strong>Findings indicate that a brief IOP intervention is effective for weight restoration in underweight adolescents with EDs, functioning as both an intensification of outpatient treatment and an effective way of keeping young people in the community who are at high risk of an inpatient admission. Future research would benefit from controlled designs, explore long-term outcomes, and examine adaptations for neurodiverse populations.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13487937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kate E Murphy, Morgan J Sidari, Thomas A Skerlj, Kirsten L McMahon, Stephen Parker, Chloe Pearson, Jana Y Waldmann, Elizabeth Eggins
{"title":"Cardiovascular risk factors and serious health events in individuals with eating disorders: a systematic review.","authors":"Kate E Murphy, Morgan J Sidari, Thomas A Skerlj, Kirsten L McMahon, Stephen Parker, Chloe Pearson, Jana Y Waldmann, Elizabeth Eggins","doi":"10.1186/s40337-026-01691-x","DOIUrl":"10.1186/s40337-026-01691-x","url":null,"abstract":"<p><strong>Background: </strong>This systematic review aimed to determine how cardiovascular risk factors are associated with serious adverse health events in individuals with eating disorders, aiming to inform clinical decision-making about hospital admission and monitoring.</p><p><strong>Main body: </strong>We searched 15 multidisciplinary databases from inception to October 2025 following PRISMA guidelines. Eligible studies needed to compare outcomes between individuals with eating disorders who exhibited specific cardiovascular parameters (e.g., resting heart rate, blood pressure, QTc prolongation) and those who did not. Eligible outcomes were serious adverse health events, including death, cardiac arrest, malignant arrhythmias and/or cardiac failure. Of 14,034 de-duplicated records, six studies met inclusion criteria, all focusing exclusively on anorexia nervosa (AN). Only two provided high-confidence evidence. Hypotension at admission was associated with 8.65-fold increased likelihood of in-hospital mortality (95% CI 5.45, 13.7). Composite cardiac complications predicted 3.29-fold increased odds of mortality (95% CI 1.27, 8.55). The evidence for QTc prolongation was insufficient and for the presence of bradycardia was low confidence. Postural hypotension, postural tachycardia, resting tachycardia, and heart rate variability were not examined in any eligible study.</p><p><strong>Conclusion: </strong>Limited evidence exists for the predictive validity of most cardiovascular parameters for serious adverse health events in eating disorders. Hypotension emerged as the clearest predictor; however, the absence of evidence should not be interpreted as evidence of absence. Current clinical guidelines appropriately adopt a cautious approach given this evidence gap. Large-scale, multi-site cohort studies are needed to establish which cardiovascular parameters predict imminent risk and to examine eating disorder diagnoses beyond AN.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13580000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}