Mechteld M van den Hoek Ostende, Giulia Brizzi, Valentina Meregalli, Philipp A Schroeder, Enrico Collantoni
{"title":"Psychological distance affects real movements in virtual reality: distance to food in anorexia nervosa.","authors":"Mechteld M van den Hoek Ostende, Giulia Brizzi, Valentina Meregalli, Philipp A Schroeder, Enrico Collantoni","doi":"10.1186/s40337-025-01357-0","DOIUrl":"10.1186/s40337-025-01357-0","url":null,"abstract":"<p><strong>Background: </strong>Patients with restrictive Anorexia Nervosa (AN-R) severely restrict their food intake, often showing significant food avoidance behavior, especially for diet-goal threatening and high-calorie foods. Still, stringent comparisons of avoidance behaviors in relation to calorie dense foods, low-calorie food and abstract (amodal) food cues are required to better understand the underlying mechanisms.</p><p><strong>Methods: </strong>Approach-avoidance behavior was measured in individuals with AN-R (n = 21) and Healthy Controls (HC; n = 19) using a virtual reality stop-signal task. In a virtual environment, participants had to reach a digitally rendered hand toward low-calorie, high-calorie and amodal (packaged) food cues, as well as nonfood cues (shoes). If a stop-sign appeared, they had to inhibit this movement (stop-trials). They also rated how much they liked and wanted each stimulus on a visual analog scale from 0 to 100.</p><p><strong>Results: </strong>Participants showed more approach behavior towards amodal food cues compared to high-calorie concrete food cues (t[39] = 25.38, p <.001, d = 4.01). Furthermore, patients with AN-R reported lower wanting for high-calorie foods (t[37] = 2.13, p =.040, d = 2.13) and greater wanting for nonfood cues (t[37] = -3.35, p =.002, d = 3.35). Across groups, liking was highest for high-calorie food, both packaged (t[39] = 4.03, p =.002, d = 0.40) and unpackaged (t[39] = 3.53, p =.007, d = 0.36).</p><p><strong>Conclusions: </strong>Food presentation can influence approach behavior toward food cues. Future research is needed to determine whether the use of abstract food cues can facilitate food approach behavior in individuals with AN-R.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"169"},"PeriodicalIF":4.5,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144795903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From disavowal to dialogue: forging collaborative ethical, clinical, and medical approaches to severe and enduring anorexia nervosa.","authors":"Maryrose Bauschka, Anne Marie O'Melia","doi":"10.1186/s40337-025-01350-7","DOIUrl":"10.1186/s40337-025-01350-7","url":null,"abstract":"<p><p>Anorexia nervosa carries one of the highest mortality rates among psychiatric disorders, yet care pathways for individuals with longstanding, treatment-resistant illness continue to pose significant challenges. Drawing on scholarly critique, lived-experience perspectives, and recent shifts in clinical stance, most notably Dr. Jennifer Gaudiani's formal published disavowal of the term \"terminal anorexia nervosa\", this commentary proposes forward-looking strategies across four domains: terminology, capacity assessment, systemic supports, and integrated care frameworks. We advocate replacing deterministic labels with descriptive terms that honor recovery potential and the full spectrum of patient experience.We examine challenges in evaluating decision-making capacity among individuals with ego-syntonic illnesses, especially when severely malnourished, recommend standardized, multidisciplinary, decision-specific protocols, and acknowledge that patients can retain capacity to make informed choices even when severely ill from an eating disorder.We review systemic barriers, including uneven access to specialized services and the impact of clinician moral distress, and suggest institutional supports such as ethics consultation and peer supervision.Finally, we outline an integrated model that combines specialized eating disorder treatment with palliative principles grounded in supported decision-making, emphasizing autonomy and hope. Research and training priorities include standardizing capacity-assessment tools, developing curricula on clinician resilience and ethics, evaluating outcomes of combined palliative-eating disorder interventions, and co-creating guidelines with lived-experience stakeholders. By focusing on actionable next steps, this commentary aims to guide ethical discourse and strengthen compassionate, equitable care for those who decline recommended interventions.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"166"},"PeriodicalIF":4.5,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12323254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mark John Castro, Zyana Gall, Alana Gall, Hilary Smith, Kanita Kunaratnam
{"title":"Validated and culturally specific screening tools and early response programs for the detection and prevention of eating disorders among First Nations peoples in Australia: a scoping review.","authors":"Mark John Castro, Zyana Gall, Alana Gall, Hilary Smith, Kanita Kunaratnam","doi":"10.1186/s40337-025-01334-7","DOIUrl":"10.1186/s40337-025-01334-7","url":null,"abstract":"<p><strong>Background: </strong>Eating disorders (EDs) are complex mental health conditions that can have severe health consequences, exacerbating the overall disease burden and causing significant economic impacts on healthcare systems. Globally, cultural and societal factors influence the presentation and management of these disorders, necessitating culturally specific approaches to screening and prevention. Among First Nations peoples in Australia, the intersection of historical, cultural, and social factors offers both context and strength in addressing EDs, while also presenting distinct challenges in identification and prevention.</p><p><strong>Objective: </strong>This scoping review seeks to map and evaluate existing research on culturally specific and validated screening tools and early response programs tailored for the prevention and detection of EDs among the First Nations population in Australia. The goal is to acquire relevant information and identify gaps that need to be addressed in the literature to develop standardised screening tools and early response programs that are validated, effective, and culturally sensitive.</p><p><strong>Design: </strong>A literature search was conducted through seven online academic databases (PubMed, MEDLINE, PsycINFO, Scopus, Web of Science, CINAHL, and Informit) and included publications from 2009 to 2024. The search strategy focused on ED prevention strategies among First Nations peoples in Australia, with emphasis on screening tools and early response programs.</p><p><strong>Results: </strong>The scoping review found no culturally specific and validated screening tools and early response programs exist that have been specifically developed for First Nations peoples in Australia. After removing the cultural specificity criterion, seven studies were found that utilised six different screening tools and one early response program. Participant demographics across these studies were predominantly Caucasians or non-Indigenous, with First Nations individuals being underrepresented in sample sizes.</p><p><strong>Conclusion: </strong>The findings reveal significant gaps in literature on culturally specific screening tools and early response programs for eating disorders among First Nations peoples in Australia. Existing studies often underrepresent these populations and rely on tools designed for non-Indigenous groups, questioning the generalisability of the effectiveness to First Nations peoples in Australia. This review emphasises the need for future research to adopt culturally competent methodologies led by First Nations peoples. Developing culturally specific tools and programs is crucial for improving health outcomes and achieving equitable mental health within Australian healthcare systems, ensuring that resources are justly distributed.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"167"},"PeriodicalIF":4.5,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12323021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Co-occurring eating disorder and psychosis: a lived experience case exploration with examples and suggestions for personalized integrated treatment approach.","authors":"Rosiel Elwyn","doi":"10.1186/s40337-025-01270-6","DOIUrl":"10.1186/s40337-025-01270-6","url":null,"abstract":"","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"164"},"PeriodicalIF":4.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12317487/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144765661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Angeles Peláez-Fernández, Nicolás Sánchez-Álvarez, Jennifer S Mills, Natalio Extremera
{"title":"Spanish version of the brief Eating Disorder Examination Questionnaire (EDE-Q7): psychometric properties, dimensional structure, and sex invariance in a Spanish adult sample.","authors":"María Angeles Peláez-Fernández, Nicolás Sánchez-Álvarez, Jennifer S Mills, Natalio Extremera","doi":"10.1186/s40337-025-01354-3","DOIUrl":"10.1186/s40337-025-01354-3","url":null,"abstract":"<p><strong>Background: </strong>The Eating Disorder Examination Questionnaire (EDE-Q) is a widely used measure for eating disorders. Research on the shorter 7-item 3-factor version of the scale (EDE-Q7) supports the validity of that brief measure. Moreover, EDE-Q7 may be especially useful in large epidemiological investigations and clinical contexts because of its shorter length. The current study examined the psychometric properties and factor structure of the Spanish language version of the EDE-Q7 in a sample of Spanish adults.</p><p><strong>Methods: </strong>A non-clinical sample of 1163 adults living in Spain (806, 69.3% women) completed the EDE-Q7, the EDE-Q, and other measures of abnormal eating attitudes, depression, stress, anxiety, self-esteem, and life satisfaction.</p><p><strong>Results: </strong>Confirmatory factor analysis showed an adequate fit for the EDE-Q7 with a three-factor structure identified as dietary restraint, body dissatisfaction, and shape/weight over evaluation. The EDE-Q7 exhibited good internal consistency, and the results corroborated measurement invariance across sex. The instrument revealed positive correlations with the EDE-Q and abnormal eating attitudes. The EDE-Q7 also showed significant associations in the expected direction with body mass index, self-esteem, stress, anxiety, depression, and life satisfaction.</p><p><strong>Conclusions: </strong>Our findings support the validity and factor structure of the Spanish version of EDE-Q7 in a sample of Spanish men and women, implying that the questionnaire can be used as an autonomous measure. Measurement invariance suggests that the instrument may be appropriate for Spanish college-aged men and women and community adults.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"165"},"PeriodicalIF":4.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12317477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144765662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Simar Singh, Erin E Reilly, Catherine R Drury, Alan Duffy, Philip S Mehler, Erin C Accurso, Kianna Zucker, Naomi Lynch, Daniel Le Grange, Renee D Rienecke, Sasha Gorrell
{"title":"Preliminary validation of developmental weight suppression in youth with transdiagnostic eating disorders.","authors":"Simar Singh, Erin E Reilly, Catherine R Drury, Alan Duffy, Philip S Mehler, Erin C Accurso, Kianna Zucker, Naomi Lynch, Daniel Le Grange, Renee D Rienecke, Sasha Gorrell","doi":"10.1186/s40337-025-01349-0","DOIUrl":"10.1186/s40337-025-01349-0","url":null,"abstract":"<p><strong>Background: </strong>Weight suppression (WS), traditionally defined as the difference between highest past and current weights at adult height, is a correlate and predictor of eating disorder (ED) psychopathology. However, for growing adolescents, it may be more appropriate to use a developmentally-adjusted calculation of WS. This study compared how developmental WS, calculated using zBMIs, compared with traditional WS, calculated using weights, as correlate of ED psychopathology in treatment-seeking adolescents with transdiagnostic EDs.</p><p><strong>Methods: </strong>Adolescents with EDs (N = 93) completed the Eating Disorder Examination Questionnaire (EDE-Q) at presentation to outpatient care. Weight histories were extracted from medical records. Regressions examined the association between each measure of WS and EDE-Q scores, adjusting for ED diagnosis. Dominance analyses with bootstrapping assessed whether developmental WS outperformed traditional WS.</p><p><strong>Results: </strong>Developmental WS negatively associated with EDE-Q Shape (sr<sup>2</sup> = 0.05, p =.020) and Weight Concern (sr<sup>2</sup> = 0.05, p =.021). In contrast, traditional WS did not associate with any EDE-Q scores. Although dominance weights were larger for developmental WS compared to traditional WS, bootstrap sampling revealed no significant differences in magnitudes.</p><p><strong>Conclusions: </strong>Results preliminarily support developmental WS as a correlate of body image concerns in youth with EDs, though replication is needed.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"163"},"PeriodicalIF":4.5,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12315326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicole Obeid, Niana Lavallée, Abigail H M Bradley, Mark L Norris
{"title":"Considerations for informing precision psychiatry in eating disorders: Foundations for future practice.","authors":"Nicole Obeid, Niana Lavallée, Abigail H M Bradley, Mark L Norris","doi":"10.1186/s40337-025-01351-6","DOIUrl":"10.1186/s40337-025-01351-6","url":null,"abstract":"<p><p>Eating disorders (EDs) are multisystemic, debilitating, and complex illnesses that affect many young Canadians. These disorders are associated with high rates of medical complications, psychiatric and physical comorbidities, functional impairment, family distress, and financial burden. Despite the severity and increasing prevalence of EDs in youth, advancements in understandings of the pathophysiology and treatment of EDs have remained limited over the past three decades. This trend may be shaped by the chronic underfunding of the field, reliance on small sampled cross-sectional studies, and the notable lack of research focused on youth with EDs from historically underrepresented communities. Current treatment practices demonstrate modest efficacy and often omit the complex, heterogeneous presentations, development, and maintenance of pediatric EDs. Large-scale, multiaxial datasets are necessary to elucidate ED etiology and enable phenotyping. This is a critical step towards implementing future precision psychiatry and personalized treatment advances. In this commentary, we share our experience of conceptualizing a precision ED data and bio-registry, EDBioMAP: Eating Disorder Bio-Registry and Multiaxial Precision Health Platform, and suggest necessary pillars to inform, implement, and drive the successful use of precision psychiatry in pediatric ED care. Effective data utilization requires actionable steps and includes: (1) establishing strategic partnerships; (2) incorporating measurement-based care into clinical practice; (3) collecting novel biological markers; (4) developing minimum datasets; and (5) leveraging predictive modelling techniques. Strategic and standardized data integration is imperative to informing the future use of precision psychiatry for EDs. It can lend well to igniting multi-site collaboration to enhance large datasets necessary for this type of work and offers avenues for future development of personalized treatment interventions and clinical decision-making tools for youth with EDs.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"162"},"PeriodicalIF":4.5,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12312325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Potyrcha, Aminata Ali, Benjamin Carrot, France Hirot, Nathalie Godart
{"title":"Trajectories of change in body mass index during inpatient treatment for severe anorexia nervosa during adolescence: predictive factors and hospitalization outcomes.","authors":"Anna Potyrcha, Aminata Ali, Benjamin Carrot, France Hirot, Nathalie Godart","doi":"10.1186/s40337-025-01339-2","DOIUrl":"10.1186/s40337-025-01339-2","url":null,"abstract":"<p><strong>Background: </strong>Weight restoration is one of the main goals of treatment for AN. Weight trajectories derive from various elements including baseline personal characteristics and factors linked to the course of treatment. The aim of our research was to identify different BMI trajectories during inpatient treatment, to examine whether patient characteristics were predictive of the nature of these trajectories, and to examine how they affect hospitalization outcomes.</p><p><strong>Methods: </strong>The study population consisted of 310 female AN inpatients. To analyse the data, we examined trajectories of change in BMI, using a clustering algorithm: k-means for longitudinal data.</p><p><strong>Results: </strong>We chose a four-trajectory model. The most common was the A trajectory, which we labelled \"severe and compliant\" (38.71%, N = 120). The second most frequent (28.71%, N = 89) was B trajectory, labelled \"the least severe with weight fluctuations before discharge\", it is situated above the others over the whole period. Trajectory C, which we labelled \"severe, with high dissatisfaction scores and long lengths of stay\" included 25.16% (N = 78) of patients. The D trajectory, which we labelled \"resistant and non-compliant\", was the smallest with only 23 subjects (7.42%), situated below the others. Significant differences were found across trajectories concerning: lifetime, admission and target BMI, satisfaction with target BMI, menarcheal status and the duration of amenorrhea, previous inpatient treatments and parental psychiatric disorders. Factors that differed in the course of treatment were: length of stay, dropout, discharge BMI, changes in target weight, tube feeding and transfers to intensive care unit.</p><p><strong>Conclusion: </strong>This study is one of the few to examine BMI trajectories during treatment for AN. It shows that different trajectories lead to different outcomes. A better understanding of the underlying clinical profiles associated with trajectories could enable more personalized care and an improved outcome.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"160"},"PeriodicalIF":4.5,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Emotion dysregulation and eating disorder symptoms: a network analysis in college students with subclinical eating disorders.","authors":"Yanan Lian, Sihan Liu, Di Zhang, Dongdong Qiao, Zhengze Zhang, Guolin Mi, Zhenhua Liu, Xinchun Wu","doi":"10.1186/s40337-025-01325-8","DOIUrl":"10.1186/s40337-025-01325-8","url":null,"abstract":"<p><strong>Background: </strong>Emotion dysregulation is a critical factor in the development and maintenance of eating disorders (EDs), but the specific associations between emotion dysregulation dimensions and specific eating disorder symptoms in subclinical populations remain unclear. This study investigated the unique associations in college students with subclinical eating disorders using a network analysis approach.</p><p><strong>Methods: </strong>A total of 282 college students with subclinical eating disorders were screened with an online questionnaire. They completed the Eating Disorder Examination Questionnaire (EDE-Q ≥ 1.27) and the Difficulties in Emotion Regulation Scale. Network analysis was applied to identify central and bridge nodes, as well as key connections between eating disorder symptoms and emotion dysregulation dimensions.</p><p><strong>Results: </strong>Preoccupation with food and eating emerged as the most influential symptom in the network. The Clarity and Non-acceptance dimensions of emotion dysregulation acted as critical bridge nodes linking emotion dysregulation and ED symptoms. Specific dimensions of emotion dysregulation demonstrated distinct associations with different ED symptomatology. For instance, the Impulse dimension was associated with restriction. The Goals dimensions were associated with lower levels of binge eating and compensatory behaviors. The Strategy dimension was mainly related to ED symptoms accompanying emotional experience.</p><p><strong>Conclusions: </strong>The findings highlight the role of emotion dysregulation in the maintenance of subclinical EDs and underscore the need for targeted interventions focusing on emotional understanding and acceptance. While network analysis provides novel insights into early-stage ED pathology, limitations such as cross-sectional design and reliance on self-reported data should be considered. Future longitudinal studies are needed to validate these associations.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"161"},"PeriodicalIF":4.5,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309016/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Childhood maltreatment and longitudinal trajectories of disordered eating behaviors: sociodemographic moderators and behavior-specific sensitivity analyses.","authors":"Lina Modjarrad, Nicole Marlow, Avery Bollinger, Yenan Zhu","doi":"10.1186/s40337-025-01355-2","DOIUrl":"10.1186/s40337-025-01355-2","url":null,"abstract":"<p><strong>Objective: </strong>Disordered eating behaviors (DEBs) represent a significant public health issue, with childhood maltreatment emerging as a potential contributing factor. However, the longitudinal impact of maltreatment on the progression of disordered eating behaviors from adolescence to adulthood remains inadequately understood. This study aims to explore how childhood maltreatment influences the trajectory of disordered eating behaviors, focusing on potential moderating factors such as sociodemographic variables, race, and sex.</p><p><strong>Methods: </strong>Data from Waves I-III of Add Health (ages 11-26) were used to assess DEB trajectories, with retrospective childhood maltreatment data collected in Wave IV. Repeated measures mixed-effects models accounted for intra-individual variability, adjusting for relevant covariates. Interaction effects between maltreatment subtypes and sociodemographic covariates (sex, race/ethnicity, income) were analyzed to examine how these intersections influenced DEB trajectories.</p><p><strong>Results: </strong>Among the 15,363,384 participants, 49.2% experienced childhood maltreatment. Adjusted models indicated significant increases in DEBs over time, particularly between Waves II and III (β = 19.9, p < 0.001). Although physical abuse (β = 1.88, p = 0.1330), verbal abuse (β = -0.67, p = 0.4529), and sexual abuse by a parent (β = 1.59, p = 0.4204) were not significant predictors of worsening behaviors, stratified analyses revealed that low-income individuals exposed to non-familial sexual abuse demonstrated the steepest worsening of DEBs (β = 26.5, p = 0.0048). Interaction effects revealed that Asian or Pacific Islander participants experiencing verbal abuse, and low-income individuals exposed to non-familial sexual abuse demonstrated pronounced worsening of DEBs. We observed significant sex differences: males exhibited higher levels of worsening behaviors over time (β = -10.8, p < 0.0001).</p><p><strong>Conclusion: </strong>Our findings suggest that sociodemographic characteristics (sex, race, income) may moderate the persistence of DEBs, underscoring the need for trauma-informed and tailored interventions. Addressing childhood adversity through public health, policy, and clinical efforts can help support those at highest risk. Future research should examine these trajectories beyond early adulthood and explore protective factors that may buffer against long-term DEB risk.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"159"},"PeriodicalIF":4.5,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}