Nicole Obeid, Niana Lavallée, Abigail H M Bradley, Mark L Norris
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引用次数: 0
Abstract
Eating disorders (EDs) are multisystemic, debilitating, and complex illnesses that affect many young Canadians. These disorders are associated with high rates of medical complications, psychiatric and physical comorbidities, functional impairment, family distress, and financial burden. Despite the severity and increasing prevalence of EDs in youth, advancements in understandings of the pathophysiology and treatment of EDs have remained limited over the past three decades. This trend may be shaped by the chronic underfunding of the field, reliance on small sampled cross-sectional studies, and the notable lack of research focused on youth with EDs from historically underrepresented communities. Current treatment practices demonstrate modest efficacy and often omit the complex, heterogeneous presentations, development, and maintenance of pediatric EDs. Large-scale, multiaxial datasets are necessary to elucidate ED etiology and enable phenotyping. This is a critical step towards implementing future precision psychiatry and personalized treatment advances. In this commentary, we share our experience of conceptualizing a precision ED data and bio-registry, EDBioMAP: Eating Disorder Bio-Registry and Multiaxial Precision Health Platform, and suggest necessary pillars to inform, implement, and drive the successful use of precision psychiatry in pediatric ED care. Effective data utilization requires actionable steps and includes: (1) establishing strategic partnerships; (2) incorporating measurement-based care into clinical practice; (3) collecting novel biological markers; (4) developing minimum datasets; and (5) leveraging predictive modelling techniques. Strategic and standardized data integration is imperative to informing the future use of precision psychiatry for EDs. It can lend well to igniting multi-site collaboration to enhance large datasets necessary for this type of work and offers avenues for future development of personalized treatment interventions and clinical decision-making tools for youth with EDs.
期刊介绍:
Journal of Eating Disorders is the first open access, peer-reviewed journal publishing leading research in the science and clinical practice of eating disorders. It disseminates research that provides answers to the important issues and key challenges in the field of eating disorders and to facilitate translation of evidence into practice.
The journal publishes research on all aspects of eating disorders namely their epidemiology, nature, determinants, neurobiology, prevention, treatment and outcomes. The scope includes, but is not limited to anorexia nervosa, bulimia nervosa, binge eating disorder and other eating disorders. Related areas such as important co-morbidities, obesity, body image, appetite, food and eating are also included. Articles about research methodology and assessment are welcomed where they advance the field of eating disorders.