Hernando Gaitán-Lee, Andres Eduardo Araque Melo, María Fernanda Santoyo Barco, Gustavo Pineda Diaz, Mauricio Acosta
{"title":"Improvement of cognitive function in patients undergoing total hip replacement: narrative review of the literature.","authors":"Hernando Gaitán-Lee, Andres Eduardo Araque Melo, María Fernanda Santoyo Barco, Gustavo Pineda Diaz, Mauricio Acosta","doi":"10.1530/EOR-2026-0011","DOIUrl":"https://doi.org/10.1530/EOR-2026-0011","url":null,"abstract":"<p><strong>Purpose: </strong></p><p><strong>Methods: </strong></p><p><strong>Results: </strong></p><p><strong>Conclusion: </strong></p>","PeriodicalId":48598,"journal":{"name":"Efort Open Reviews","volume":"11 9","pages":"955-958"},"PeriodicalIF":4.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148882217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Praveen Sritharan, Varun Jain, Matthew Cecere, Darius Luke Lameire, Jaskarndip Chahal, David Wasserstein, Amit Atrey, Amir Khoshbin
{"title":"Assessment of 'spin' in the abstracts of systematic reviews in leading orthopaedic surgery journals over the past 10 years: a cross-sectional methodological study.","authors":"Praveen Sritharan, Varun Jain, Matthew Cecere, Darius Luke Lameire, Jaskarndip Chahal, David Wasserstein, Amit Atrey, Amir Khoshbin","doi":"10.1530/EOR-2025-0242","DOIUrl":"10.1530/EOR-2025-0242","url":null,"abstract":"<p><strong>Aim: </strong></p><p><strong>Methods: </strong></p><p><strong>Results: </strong></p><p><strong>Conclusion: </strong></p><p><strong>Level of evidence: </strong>IV.</p>","PeriodicalId":48598,"journal":{"name":"Efort Open Reviews","volume":"11 9","pages":"939-948"},"PeriodicalIF":4.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13548304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148882190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in the etiology of congenital scoliosis: from morphology to spatiotemporal molecular mechanisms (2015-2025).","authors":"Yutian Niu, Hongyi Zhou, Xu'an Huang, Jianxiong Shen","doi":"10.1530/EOR-2026-0006","DOIUrl":"10.1530/EOR-2026-0006","url":null,"abstract":"<p><p>Congenital scoliosis and congenital vertebral malformations arise from heterogeneous disruptions of vertebral segmentation and formation, leading to a highly variable clinical morphology and associated anomalies. Over the past decade (2015-2025), human genetics and developmental biology have clarified core etiologic pathways, particularly somitogenesis/segmentation clock-wavefront signaling and TBX6-associated congenital scoliosis, while supporting multi-factorial contributions in many apparently sporadic cases. This review integrates morphology with spatiotemporal embryologic windows, linking axial patterning (e.g. RA-HOX context), epigenetic regulation, segmentation clock signaling (Notch/WNT/FGF), and downstream tissue-scale effectors to vertebral segmentation defects and three-dimensional curve phenotypes. We propose an evidence-grading scheme (levels A-D) to differentiate well-supported mechanisms and clinically actionable genetic findings from emerging hypotheses and preclinical signals. The synthesis highlights practical implications for molecular diagnosis and variant interpretation, phenotype-informed test selection, and counseling, while outlining priority directions for resolving non-coding/structural variation, gene-environment interactions, and mechanistic validation.</p>","PeriodicalId":48598,"journal":{"name":"Efort Open Reviews","volume":"11 9","pages":"1005-1014"},"PeriodicalIF":4.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13548303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148882239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marie-Aude Munoz, Maria Khvesyuk, Victor Leroux, Floris Van Rooij, Mo Saffarini, Camille Rodaix, Matthieu Lalevee
{"title":"No differences in union rates between grafts for subtalar arthrodesis.","authors":"Marie-Aude Munoz, Maria Khvesyuk, Victor Leroux, Floris Van Rooij, Mo Saffarini, Camille Rodaix, Matthieu Lalevee","doi":"10.1530/EOR-2024-0202","DOIUrl":"10.1530/EOR-2024-0202","url":null,"abstract":"<p><strong>Purpose: </strong></p><p><strong>Methods: </strong></p><p><strong>Results: </strong></p><p><strong>Conclusion: </strong></p>","PeriodicalId":48598,"journal":{"name":"Efort Open Reviews","volume":"11 8","pages":"894-902"},"PeriodicalIF":4.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13452036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Timing of surgery in patients with hip fracture: a systematic review with meta-analysis and trial sequential analysis (2017-2024).","authors":"Wei Yan, Hanning Wang, Zhe Li, Tianlong Jiang, Jingwu Li, Chao Jiang","doi":"10.1530/EOR-2025-0164","DOIUrl":"10.1530/EOR-2025-0164","url":null,"abstract":"<p><strong>Purpose: </strong></p><p><strong>Methods: </strong></p><p><strong>Results: </strong></p><p><strong>Conclusion: </strong></p>","PeriodicalId":48598,"journal":{"name":"Efort Open Reviews","volume":"11 8","pages":"903-912"},"PeriodicalIF":4.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13452042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E Carlos Rodríguez-Merchán, Inmaculada Moracia-Ochagavía, Alberto D Delgado-Martínez
{"title":"Total ankle replacement versus ankle fusion for end-stage ankle osteoarthritis: a narrative review of the latest literature data (2023-2025).","authors":"E Carlos Rodríguez-Merchán, Inmaculada Moracia-Ochagavía, Alberto D Delgado-Martínez","doi":"10.1530/EOR-2025-0106","DOIUrl":"10.1530/EOR-2025-0106","url":null,"abstract":"<p><p>This review compares the outcomes of total ankle replacement (TAR) and ankle fusion (AF) in patients with end-stage ankle osteoarthritis (OA) based on recent comparative studies (1 January 2023 to 31 December 2025). Racial/ethnic, socioeconomic, and payer status disparities have been reported in the likelihood of experiencing TAR versus AF for ankle OA. A prospective multicentre study with level II evidence found that the long-term clinical results of TAR and AF were similar. A meta-analysis identified TAR as the superior intervention, demonstrating significant advantages in patient-reported outcome measures. Three systematic reviews have reached the following conclusions: i) postoperative outcomes are similar in TAR and AF; ii) TAR and AF have similar complication rates (both minor and major); iii) both TAR and AF are safe and effective surgical treatments for ankle OA; besides, TAR had notable lower total complications, implant removals, adjacent level fusion surgeries, and non-union/open reduction and internal fixation surgeries after the index procedure. The existence of mixed evidence found in the literature makes it necessary to select the surgical technique to be used (TAR or AF) on an individual basis. To definitively determine which procedure is more appropriate in advanced ankle OA, more and better-designed studies are required, given that the results reported thus far do not permit to determine with absolute certainty which of the two procedures, TAR or AF, is more adequate.</p>","PeriodicalId":48598,"journal":{"name":"Efort Open Reviews","volume":"11 8","pages":"888-893"},"PeriodicalIF":4.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13452031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148671016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk factors for recurrence of chronic ankle instability following arthroscopic reconstruction: a meta-analysis.","authors":"Jean-Charles Giunta, Philippe Beaudet","doi":"10.1530/EOR-2024-0207","DOIUrl":"10.1530/EOR-2024-0207","url":null,"abstract":"<p><strong>Purpose: </strong></p><p><strong>Methods: </strong></p><p><strong>Results: </strong></p><p><strong>Conclusion: </strong></p><p><strong>Level of evidence: </strong>Meta-analysis, Level IV.</p>","PeriodicalId":48598,"journal":{"name":"Efort Open Reviews","volume":"11 8","pages":"880-887"},"PeriodicalIF":4.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13452038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vanesa Lovětínská, Andrej Sukop, Matěj Patzelt, Jozef Kučerák, Michael Kamenisty
{"title":"Orthoplastic soft tissue management in lower limb open tibial fractures based on the angiosome concept: a narrative review.","authors":"Vanesa Lovětínská, Andrej Sukop, Matěj Patzelt, Jozef Kučerák, Michael Kamenisty","doi":"10.1530/EOR-2024-0217","DOIUrl":"10.1530/EOR-2024-0217","url":null,"abstract":"<p><p>The purpose of this article is to introduce the angiosome concept in the lower legs and its consideration in severe soft tissue injuries in open tibial fractures. The main aim is to focus on the vascularity and perforators in the crura and to emphasise step-by-step time management and proper debridement for securing the maximal viability of the soft tissue before the reconstruction phase. So far, many publications have presented optimal traumatological protocols and timing in lower leg injuries and many reviews have compared fracture stabilisation and flap reconstruction options; however, no consensus exists. Radical and immediate debridement is crucial for minimising infection complications, revision surgeries and total healthcare costs, early definitive reconstruction, limb salvage success, decreased hospitalisation stay and better long-term quality-of-life outcome for the patients. The fundamental orthoplastic approach has been an indisputably accepted strategy since its introduction in the 1990s by Levin. Unfortunately, not all centres are staffed with a plastic surgeon 24/7. Furthermore, transportation to the tertiary specialist centre is often delayed; hence, we believe that a correct primary soft tissue and antibiotics administration protocol can be provided in all medical centres by orthopaedists. So, the basic knowledge of the principles of lower leg vascularity is, therefore, essential. In the difficult cases of the Anderson-Gustilo IIIC fractures, we provide some of the latest recommendations for soft tissue viability verification and blood perfusion improvement, when considering limb salvage versus amputation. This narrative review was developed in accordance with PRISMA 2020 recommendations for transparency in study selection and reporting.</p>","PeriodicalId":48598,"journal":{"name":"Efort Open Reviews","volume":"11 7","pages":"868-879"},"PeriodicalIF":4.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13326731/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148363156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vasileios Giannatos, Ioannis Siozos, Irini Tatani, Andreas Panagopoulos, Panagiotis Antzoulas, Sofia Xergia
{"title":"In vivo biomechanics after total hip arthroplasty: a state-of-the-art systematic review.","authors":"Vasileios Giannatos, Ioannis Siozos, Irini Tatani, Andreas Panagopoulos, Panagiotis Antzoulas, Sofia Xergia","doi":"10.1530/EOR-2026-0003","DOIUrl":"10.1530/EOR-2026-0003","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review aimed to synthesize current literature on in vivo biomechanics following total hip arthroplasty, emphasizing objective laboratory assessments and surgical modifiers to address persistent functional deficits despite favorable clinical outcomes.</p><p><strong>Methods: </strong>A PRISMA-guided systematic review was conducted across seven databases (PROSPERO: CRD42024550457). Eligible studies included human subjects with objective postoperative biomechanical assessments (e.g. 3D motion analysis, force plates, dual fluoroscopy) compared against healthy or contralateral limbs. Data on spatiotemporal parameters, kinematics, kinetics, and surgical subgroups were extracted from 50 included studies.</p><p><strong>Results: </strong>Key findings revealed persistent reductions in hip joint power, gait speed, and stride length, along with joint loading asymmetries >1 year post-operatively. While the direct anterior approach showed faster early gait normalization, the surgical approach had a minimal long-term impact. Conversely, restoring femoral offset and anteversion was strongly associated with improved kinetics. Older patients exhibited greater compensatory trunk movements.</p><p><strong>Conclusion: </strong>The choice of surgical approach has a limited influence on long-term biomechanical restoration. Surgeons should instead prioritize offset restoration, implant choice, and functional component orientation, as static imaging fails to capture dynamic edge-loading. Future rehabilitation must target persistent kinetic asymmetries that standard clinical scores overlook.</p>","PeriodicalId":48598,"journal":{"name":"Efort Open Reviews","volume":"11 7","pages":"758-769"},"PeriodicalIF":4.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13326882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148363008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shuzhong Liu, Jinyi Xing, An Song, Xi Zhou, Yong Liu
{"title":"Orthopedic preoperative evaluation and surgical strategies of hereditary multiple osteochondromas involving the spinal region.","authors":"Shuzhong Liu, Jinyi Xing, An Song, Xi Zhou, Yong Liu","doi":"10.1530/EOR-2025-0092","DOIUrl":"10.1530/EOR-2025-0092","url":null,"abstract":"<p><p>Hereditary multiple osteochondromas (HMO), previously known as hereditary multiple exostoses (HME), is a congenital skeletal developmental anomaly characterized by multiple osteochondromas that commonly grow outward from the metaphyses of long bones. Hereditary multiple exostoses is an autosomal dominant genetic disease characterized by multiple cartilage growth disorders, which affect the long bones of the limbs, scapula, and ribs, among others. Consensus on the diagnosis and treatment of spinal involvement is relatively lacking. For such patients, experience in terms of clinical screening, preoperative evaluation, surgical intervention indications and timing, surgical expertise and lessons learned, and follow-up is needed and critical. This review focuses on the clinical evaluation and orthopedic surgical treatment of HME patients with spinal involvement. It summarizes the patients' diagnosis, clinical features, and treatment strategies based on evidence from the published literature. The clinical manifestations, location of onset, and surgical intervention are summarized in detail in this review. The above contents will help improve the clinical diagnosis and treatment level of HME patients with spinal involvement internationally.</p>","PeriodicalId":48598,"journal":{"name":"Efort Open Reviews","volume":"11 7","pages":"837-848"},"PeriodicalIF":4.6,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13326722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148363161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}