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Feeding Problems Assessment Tools in Children: A Scoping Review.
IF 2 4区 医学
Children-Basel Pub Date : 2024-12-28 DOI: 10.3390/children12010037
Suci Destriatania, Judhiastuty Februhartanty, Fariz Nurwidya, Rini Sekartini
{"title":"Feeding Problems Assessment Tools in Children: A Scoping Review.","authors":"Suci Destriatania, Judhiastuty Februhartanty, Fariz Nurwidya, Rini Sekartini","doi":"10.3390/children12010037","DOIUrl":"10.3390/children12010037","url":null,"abstract":"<p><p>'Feeding problems' is a term used to describe problems that may present typically in children. Problems with feeding during infancy can result in significant negative consequences for a child's nutrition, growth, and brain development. This scoping review aims to map current research, provide summary of the available feeding problem assessment tools for children, and review current implications and the gaps between tools, providing information that academics, practitioners, and parents may find useful. Three electronic databases (PubMed, Science Direct, and ProQuest) were searched using terms related to feeding problem assessment tools in children, which included, but were not limited to, \"feeding difficult*\", \"eating problem\", \"eating difficult*\", \"tool\", \"child*\", and \"pediatric\". The following limits were implemented on the search: English language, age limit (<18 years old) and publication period (last 10 years). Data management and analysis carried out manually through discussion with the team. Authors 1 and 2 screened titles and abstracts, then full texts were discussed with the full team to identify articles that met inclusion and exclusion criteria. Data were charted into a matrix table based on these categories: author, year, population, assessment tools, usage and aspects. Thematic analysis was carried out to summarize the characteristics of the studies. There were 47 papers included in the study and analysis, in which 23 assessment tools were found. Pedi-EAT was the most frequent assessment tool used in the studies, with nine papers covering this feeding problem assessment tool. MCH-FS came in second for its chosen tool quantifying children's feeding problems, with a total of seven papers covering this tool, along with BPFAS with seven papers. In this review, 23 assessment tools were validated and tested for reliability. Pedi-EAT, MCH-FS and BPFAS were commonly used instruments. However, it is clear that no single instrument covers comprehensively all aspects of feeding problems in children. In addition, usage of the tools and wide age range indicate that further research is needed to fill the gaps.</p>","PeriodicalId":48588,"journal":{"name":"Children-Basel","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11764129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Intelligence in Pediatric Electrocardiography: A Comprehensive Review.
IF 2 4区 医学
Children-Basel Pub Date : 2024-12-27 DOI: 10.3390/children12010025
David M Leone, Donnchadh O'Sullivan, Katia Bravo-Jaimes
{"title":"Artificial Intelligence in Pediatric Electrocardiography: A Comprehensive Review.","authors":"David M Leone, Donnchadh O'Sullivan, Katia Bravo-Jaimes","doi":"10.3390/children12010025","DOIUrl":"10.3390/children12010025","url":null,"abstract":"<p><p>Artificial intelligence (AI) is revolutionizing healthcare by offering innovative solutions for diagnosis, treatment, and patient management. Only recently has the field of pediatric cardiology begun to explore the use of deep learning methods to analyze electrocardiogram (ECG) data, aiming to enhance diagnostic accuracy, expedite workflows, and improve patient outcomes. This review examines the current state of AI-enhanced ECG interpretation in pediatric cardiology applications, drawing insights from adult AI-ECG research given the progress in this field. It describes a broad range of AI methodologies, investigates the unique challenges inherent in pediatric ECG analysis, reviews the current state of the literature in pediatric AI-ECG, and discusses potential future directions for research and clinical practice. While AI-ECG applications have demonstrated considerable promise, widespread clinical adoption necessitates further research, rigorous validation, and careful consideration of equity, ethical, legal, and practical challenges.</p>","PeriodicalId":48588,"journal":{"name":"Children-Basel","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143041924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Exergaming on Morphological Variables, Biochemical Parameters, and Blood Pressure in Children and Adolescents with Overweight/Obesity: A Systematic Review with Meta-Analysis of Randomized Controlled Trials.
IF 2 4区 医学
Children-Basel Pub Date : 2024-12-27 DOI: 10.3390/children12010029
Jordan Hernandez-Martinez, Joaquín Perez-Carcamo, Hassan Melki, Izham Cid-Calfucura, Edgar Vasquez-Carrasco, Pedro Delgado-Floody, Claudio Romero, Tomás Herrera-Valenzuela, Braulio Henrique Magnani Branco, Pablo Valdés-Badilla
{"title":"Effects of Exergaming on Morphological Variables, Biochemical Parameters, and Blood Pressure in Children and Adolescents with Overweight/Obesity: A Systematic Review with Meta-Analysis of Randomized Controlled Trials.","authors":"Jordan Hernandez-Martinez, Joaquín Perez-Carcamo, Hassan Melki, Izham Cid-Calfucura, Edgar Vasquez-Carrasco, Pedro Delgado-Floody, Claudio Romero, Tomás Herrera-Valenzuela, Braulio Henrique Magnani Branco, Pablo Valdés-Badilla","doi":"10.3390/children12010029","DOIUrl":"10.3390/children12010029","url":null,"abstract":"<p><strong>Objectives: </strong>This systematic review with meta-analysis aimed to evaluate the available body of published peer-reviewed studies on the effects of exergaming (EXG) compared to the control group (CG) on morphological variables, biochemical parameters, and blood pressure in children and adolescents with overweight/obesity.</p><p><strong>Methods: </strong>A systematic literature search was conducted until September 2024 using five databases: PubMed, Medline, CINAHL Complete, Scopus, and Web of Science. PRISMA, TESTEX, RoB 2, and GRADE tools assessed the methodological quality and certainty of evidence. Hedge's g effect sizes (ES) for morphological, biochemical, and blood pressure variables were calculated for meta-analyses. Using a random effects model, potential sources of heterogeneity were selected, including subgroup analyses (age) and single training factor analysis (program duration, training frequency). The protocol was registered in PROSPERO (code: CRD42024626992).</p><p><strong>Results: </strong>Out of 72 records, 6 randomized controlled trials with 191 children and adolescents with overweight/obesity were included. Nine meta-analyses were performed, showing significant decreases in body mass index (<i>p</i> = 0.04), waist circumference (<i>p</i> = 0.03), and systolic blood pressure (<i>p</i> = 0.007). However, no significant improvements were observed in diastolic blood pressure, body fat percentage, total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides, and glucose. Subgroup analyses showed significant decreases in total cholesterol (<15 years, ES = 0.56; <i>p</i> = 0.006), HDL-cholesterol (<15 years, ES = 0.51; <i>p</i> = 0.01), LDL-cholesterol (<15 years, ES = 0.63; <i>p</i> = 0.01), and triglycerides (<15 years, ES = 0.82; <i>p</i> = 0.000). In training duration, only significant decreases in total cholesterol (ES = 0.69; <i>p</i> = 0.02) were presented in favor of <12 weeks vs. ≥12 weeks. While in training frequency only significant decreases in triglycerides (ES = 0.70; <i>p</i> = 0.03) were reported in favor of ≥3 sessions per week vs. <3 sessions per week.</p><p><strong>Conclusions: </strong>EXG significantly decreases body mass index, waist circumference, and systolic blood pressure in children and adolescents with overweight/obesity.</p>","PeriodicalId":48588,"journal":{"name":"Children-Basel","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adolescents with Persistent Symptoms Following Acute SARS-CoV-2 Infection (Long-COVID): Symptom Profile, Clustering and Follow-Up Symptom Evaluation.
IF 2 4区 医学
Children-Basel Pub Date : 2024-12-27 DOI: 10.3390/children12010028
Marco Floridia, Danilo Buonsenso, Laura Macculi, Liliana Elena Weimer, Marina Giuliano, Flavia Pricci, Leila Bianchi, Domenico Maurizio Toraldo, Graziano Onder, The Iss Long-Covid Study Group
{"title":"Adolescents with Persistent Symptoms Following Acute SARS-CoV-2 Infection (Long-COVID): Symptom Profile, Clustering and Follow-Up Symptom Evaluation.","authors":"Marco Floridia, Danilo Buonsenso, Laura Macculi, Liliana Elena Weimer, Marina Giuliano, Flavia Pricci, Leila Bianchi, Domenico Maurizio Toraldo, Graziano Onder, The Iss Long-Covid Study Group","doi":"10.3390/children12010028","DOIUrl":"10.3390/children12010028","url":null,"abstract":"<p><strong>Background: </strong>Few studies have evaluated long-COVID in adolescents.</p><p><strong>Methods: </strong>Cohort study. Demographics, clinical data, and the presence of 30 symptoms were collected with a modified WHO form. Mean values were compared by Student's <i>t</i> test and proportions by the chi-square test or Fisher test, with trends over time analysed using the chi-square test for trend. Potential risk factors independently associated with persisting symptoms were evaluated in a multivariable logistic regression model. Clustering of cases was analysed by two-step automatic clustering.</p><p><strong>Results: </strong>A total of 97 adolescents aged 12-17 (54.6% females, 45.4% males) were evaluated. After a mean interval of 96 days (SD 52) from acute infection, the mean number of symptoms (2.8 overall) was higher for pre-Omicron (3.2 vs. 2.5 in Omicron, <i>p</i> = 0.046) and moderate/severe acute infections (4.2 vs. 2.7 in mild, <i>p</i> = 0.023). Fatigue (62.9%) and dyspnea (43.3%) were the most common symptoms, followed by headache (28.9%), thoracic pain (22.7%), diarrhea (20.6%), palpitations/tachycardia (17.5%), articular pain (15.5%), difficult concentration (14.4%), muscle pain (12.4%), taste reduction (8.2%), smell reduction (8.2%), fever (6.2%), and skin disorders (5.2%). The symptom profile was similar in males and females but showed significant differences from that observed in concurrently followed adults. After a mean interval of 340 days from infection, 45.3% still presented symptoms, with persistence associated with higher number of initial symptoms. Two clusters were defined that differed in the phase of acute infection and the number and profile of symptoms.</p><p><strong>Conclusions: </strong>Long-COVID manifestations in adolescents may differ from those observed in adults. Polisymptomaticity may predict long-term persistence.</p>","PeriodicalId":48588,"journal":{"name":"Children-Basel","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Antiviral Treatment with Intravenous Peramivir and Oral Oseltamivir for Seasonal Influenza in Children.
IF 2 4区 医学
Children-Basel Pub Date : 2024-12-27 DOI: 10.3390/children12010026
Young-Hoon Byun, Ji-Eun Kim, So-Hyun Paek, Min-Jung Kim, Soo Hyun Park, Ho-Young Song, Jaehyun Kwon
{"title":"Effectiveness of Antiviral Treatment with Intravenous Peramivir and Oral Oseltamivir for Seasonal Influenza in Children.","authors":"Young-Hoon Byun, Ji-Eun Kim, So-Hyun Paek, Min-Jung Kim, Soo Hyun Park, Ho-Young Song, Jaehyun Kwon","doi":"10.3390/children12010026","DOIUrl":"10.3390/children12010026","url":null,"abstract":"<p><strong>Background/objectives: </strong>Influenza poses significant risks in children, causing complications like febrile seizures and hospitalizations. Antiviral treatments include oseltamivir and peramivir, both FDA-approved neuraminidase inhibitors. This study aims to compare the effectiveness of intravenous peramivir and oral oseltamivir in pediatric patients presenting to an emergency department, with a primary focus on the revisit rate within 72 h post-treatment.</p><p><strong>Methods: </strong>A retrospective study analyzed 1327 children aged 1-15 years diagnosed with influenza A or B between 1 January 2019 and 29 February 2020, at a single urban hospital. Patients were divided into oseltamivir (n = 1243) and peramivir (n = 84) groups. Data included demographics, clinical symptoms, emergency department stays, and revisit rates. Fisher's exact test was used for analysis, with <i>p</i>-values < 0.05 considered significant.</p><p><strong>Results: </strong>A total of 1327 pediatric patients were included, with 1243 receiving oseltamivir and 84 receiving peramivir. Patients in the peramivir group were older (median age 5.88 years vs. 4.54 years, <i>p</i> = 0.002) and had higher rates of gastrointestinal symptoms. The emergency department length of stay was significantly longer in the peramivir group (167 min vs. 63 min, <i>p</i> < 0.001). The revisit rate within 3 days was 5.63% for oseltamivir and 9.52% for peramivir, with no statistically significant difference (<i>p</i> = 0.22).</p><p><strong>Conclusions: </strong>Peramivir presents as an effective alternative treatment for influenza in children, particularly in situations where oral administration is not feasible due to gastrointestinal intolerance, highlighting the importance of an alternative route of antiviral administration.</p>","PeriodicalId":48588,"journal":{"name":"Children-Basel","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Motor Learning Deficits in a Neonatal Mouse Model of Hypoxic-Ischemic Injury.
IF 2 4区 医学
Children-Basel Pub Date : 2024-12-27 DOI: 10.3390/children12010027
Maria Marlicz, Weronika Matysik, Emily Zucker, Sarah Lee, Hannah Mulhern, Jennifer Burnsed
{"title":"Motor Learning Deficits in a Neonatal Mouse Model of Hypoxic-Ischemic Injury.","authors":"Maria Marlicz, Weronika Matysik, Emily Zucker, Sarah Lee, Hannah Mulhern, Jennifer Burnsed","doi":"10.3390/children12010027","DOIUrl":"10.3390/children12010027","url":null,"abstract":"<p><strong>Background/objectives: </strong>Motor deficits following neonatal brain injury, from cerebral palsy to subtle deficits in motor planning, are common yet underreported. Rodent models of motor deficits in neonatal hypoxia-ischemia (HI) allow improved understanding of the underlying mechanisms and neuroprotective strategies. Our goal was to test motor performance and learning in a mouse model of neonatal HI.</p><p><strong>Methods: </strong>We induced HI in postnatal day (p)10 C57/Bl6 mice through unilateral carotid ligation followed by 60 min of 8% oxygen exposure, or a sham procedure. At p30, we assessed complex motor performance and learning using the accelerating rotarod and complex running wheel tasks.</p><p><strong>Results: </strong>In the rotarod task, HI mice performed worse than sham mice, with shorter latencies to fall (n = 6 sham, 9 HI; day 1, <i>p</i> = 0.033; day 2, <i>p</i> = 0.013; day 3, <i>p</i> = 0.023). Sham mice demonstrated improved performance across days (<i>p</i> = 0.005), and HI mice did not (<i>p</i> = 0.44). During the simple running wheel task, we observed no difference in wheel rotation and speed between groups (n = 5/group; day 1, <i>p</i> = 0.67; day 4, <i>p</i> = 0.53). However, when navigating a wheel with a random pattern of spokes removed (complex task), HI mice took longer than sham mice to reach a plateau in performance (n = 5/group; day 1, <i>p</i> = 0.02; day 4, <i>p</i> = 0.77).</p><p><strong>Conclusions: </strong>Our findings demonstrate that young adult mice exposed to HI exhibit significant deficits and delayed learning in complex motor performance compared to sham mice. HI mice do not show deficits in gross motor performance; however, more subtle impairments are present in complex motor performance and learning. This HI model exhibits subtle motor deficits relevant to findings in humans and may be a useful tool in testing further neuroprotective strategies.</p>","PeriodicalId":48588,"journal":{"name":"Children-Basel","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimally Invasive Fetoscopic Resection of Life-Threatening Amniotic Band Constrictions in a Human Fetus at 22 + 2 Weeks of Gestation Complicated by Subtotal Chorioamniotic Separation and Partial Placental Abruption.
IF 2 4区 医学
Children-Basel Pub Date : 2024-12-26 DOI: 10.3390/children12010020
Nadja Riehle, Oliver Nowak, Leila Messroghli, Samantha Wakerlin, Thomas Schaible, Thomas Kohl
{"title":"Minimally Invasive Fetoscopic Resection of Life-Threatening Amniotic Band Constrictions in a Human Fetus at 22 + 2 Weeks of Gestation Complicated by Subtotal Chorioamniotic Separation and Partial Placental Abruption.","authors":"Nadja Riehle, Oliver Nowak, Leila Messroghli, Samantha Wakerlin, Thomas Schaible, Thomas Kohl","doi":"10.3390/children12010020","DOIUrl":"10.3390/children12010020","url":null,"abstract":"<p><p>Amniotic band syndrome is a constrictive phenomenon in fetal development that can provoke limb autoamputation, malformation, trunk division, and umbilical cord strangulation. The latter two complications will ultimately lead to fetal demise if left untreated. If detected early enough, select cases may benefit from prenatal resection of the amniotic bands, thus preventing amputation and fetal death. Yet, especially in the presence of complete chorioamniotic separation, these procedures are rare, technically difficult, and not without significant risk.</p><p><strong>Objectives: </strong>The purpose of this report is to present the surgical technique and outcome of a challenging percutaneous fetoscopic intervention in a human fetus with amniotic band constrictions of a fetal thigh, retroplacental hematoma, partial placental abruption, subtotal chorioamniotic separation, and multiple amniotic bands encircling the umbilical cord.</p><p><strong>Methods: </strong>Minimally invasive, fetoscopic surgery to salvage the fetal life and lower leg was performed at 22 + 2 weeks of gestation under general maternofetal anesthesia.</p><p><strong>Results: </strong>Total resection of all amniotic bands was achieved, notwithstanding the aforementioned challenges. No surgical complications were observed. Despite preterm delivery at 25 + 4 weeks of gestation, the postnatal experience for the infant was favorable and uncomplicated as it furthermore benefitted from neonatal intensive care. At almost three years of age, the child remains healthy and demonstrates normal function of the formerly constricted leg.</p><p><strong>Conclusions: </strong>Our case shows that the combination of tested percutaneous fetoscopic techniques, high-risk obstetrics, and modern neonatology can overcome multiple obstacles in order to save a fetal patient stuck in a near-hopeless situation.</p>","PeriodicalId":48588,"journal":{"name":"Children-Basel","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Therapeutic Hypothermia and Minimal Enteral Nutrition on Short-Term Outcomes in Neonates with Hypoxic-Ischemic Encephalopathy: A 10-Year Experience from Oman.
IF 2 4区 医学
Children-Basel Pub Date : 2024-12-26 DOI: 10.3390/children12010023
Manoj Malviya, Sathiya Murthi, Dhanya Jayaraj, Vidya Ramdas, Fadia Nazir Malik, Valsala Nair, Nusrabegam Marikkar, Mukesh Talreja, Tariq Sial, Prakash Manikoth, Renjan Varghese, Khalsa Ali Al Ramadhani, Salima Al Aisry, Said Al Kindi, Ahmed Al Habsi, Ranjit Torgalkar, Munawwar Ahmed, Mohammed Al Yahmadi
{"title":"Effects of Therapeutic Hypothermia and Minimal Enteral Nutrition on Short-Term Outcomes in Neonates with Hypoxic-Ischemic Encephalopathy: A 10-Year Experience from Oman.","authors":"Manoj Malviya, Sathiya Murthi, Dhanya Jayaraj, Vidya Ramdas, Fadia Nazir Malik, Valsala Nair, Nusrabegam Marikkar, Mukesh Talreja, Tariq Sial, Prakash Manikoth, Renjan Varghese, Khalsa Ali Al Ramadhani, Salima Al Aisry, Said Al Kindi, Ahmed Al Habsi, Ranjit Torgalkar, Munawwar Ahmed, Mohammed Al Yahmadi","doi":"10.3390/children12010023","DOIUrl":"10.3390/children12010023","url":null,"abstract":"<p><strong>Background: </strong>Therapeutic hypothermia (TH) is the standard treatment for moderate to severe hypoxic-ischemic encephalopathy (HIE) in developed countries, but data on its safety and efficacy in low-middle-income countries are limited and often conflicting. The impact of enteral feeding during TH remains inadequately explored. We aimed to examine TH's effects on mortality and brain injury and evaluate the safety and effectiveness of minimal enteral feeding during TH. Here, we report our single-center experience with TH over a 10-year period\".</p><p><strong>Methods: </strong>A total of 187 neonates with moderate to severe HIE who underwent cooling were included in this retrospective study. Post-rewarming MRI scans were scored using a validated MRI scoring system. The primary outcomes were mortality and composite outcomes of mortality and brain injury.</p><p><strong>Results: </strong>The mortality rate was 3% in moderate and 25% in severe cases (<i>p</i> < 0.001). Overall, 85% (160/187) of neonates received minimal enteral nutrition. Multivariate regression analysis revealed that the severity of HIE at admission (OR 3.4 (1.03-11.6); <i>p</i> < 0.04) and gestational age (OR: 0.624 (0.442-0.882); <i>p</i> < 0.008) were independent predictors of composite outcomes of death and brain injuries. MRI score was a strong predictor of mortality (AUC: 0.89; <i>p</i> < 0.001) and of ability to orally feed at discharge (AUC: 0.73; <i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>Mortality rates associated with TH in infants with moderate-severe HIE align with those in high-income countries, and minimal enteral feeding during TH is safe. The severity of HIE, MRI scores, and feeding status are important predictors of outcomes.</p>","PeriodicalId":48588,"journal":{"name":"Children-Basel","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Managing Major Life Changes: An Exploratory Study Using the Bridges Transitions Framework to Help Foster Youth Prepare for Discharge.
IF 2 4区 医学
Children-Basel Pub Date : 2024-12-26 DOI: 10.3390/children12010022
Ande A Nesmith
{"title":"Managing Major Life Changes: An Exploratory Study Using the Bridges Transitions Framework to Help Foster Youth Prepare for Discharge.","authors":"Ande A Nesmith","doi":"10.3390/children12010022","DOIUrl":"10.3390/children12010022","url":null,"abstract":"<p><strong>Background: </strong>Adolescents in foster care endure frequent disruptive transitions, often culminating in discharge to independent living rather than reunification or adoption. Former foster youth fare poorly once on their own, with high rates of homelessness and social disconnection. This study explored the use of the Bridges Transitions Framework near the end of placement to help youth cope with the transition to adulthood.</p><p><strong>Methods: </strong>In this exploratory study, the framework was integrated into a foster agency's programming; then, we assessed outcomes using administrative data and youth interviews. Thirty-five youth participated. Status of employment, education, and social support was collected 18 months after exposure to the framework.</p><p><strong>Results: </strong>The participants reported moderate to high levels of social support, which is often limited or absent among foster care leavers. Relative to rates reported in state-level foster care data, participants had substantially higher rates of school enrollment after discharge. With very few empirically assessed models available for this population that specifically address internal coping with such substantial life changes, the Transitions Framework offers a tool that may help foster youth navigate aging out of care. Securing lasting and meaningful social support and employment and completing education remain elusive for former foster youth.</p><p><strong>Conclusions: </strong>To confirm the utility of the Transitions Framework, it is recommended to assess it with a large sample and matched comparison group over time.</p>","PeriodicalId":48588,"journal":{"name":"Children-Basel","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insufficient Sleep Syndrome in Childhood.
IF 2 4区 医学
Children-Basel Pub Date : 2024-12-26 DOI: 10.3390/children12010019
Teruhisa Miike
{"title":"Insufficient Sleep Syndrome in Childhood.","authors":"Teruhisa Miike","doi":"10.3390/children12010019","DOIUrl":"10.3390/children12010019","url":null,"abstract":"<p><p>Sleep disorders in children have a negative impact on mental and physical development, and a lack of sleep is one of the most important problems in infancy. At the age when naps are commonly accepted, the judgment of whether the amount of sleep is adequate has been based on the total amount of sleep per day. In other words, the idea is that even if the amount of sleep at night is insufficient, it is not considered insufficient if it is compensated for by taking a long nap or sleeping late on weekend mornings. However, these lifestyle habits disrupt the circadian rhythm and cause social jet lag, which is not appropriate for healthy mental and physical development. Therefore, in this review, I present the average required nighCime basic sleep duration (NBSD) of 10 h for Japanese and 11 h for Caucasian children as a judgment standard. (1) If the child sleeps less than 8 h at night, and (2) if the child sleeps less than 9 h at night or 30 to 60 min less than the required NBSD, immediate treatment is recommended. I also discuss briefly how to address sleep insufficiency in childhood.</p>","PeriodicalId":48588,"journal":{"name":"Children-Basel","volume":"12 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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