{"title":"Mechanical Circulatory Support in Congenital Heart Disease.","authors":"Áine Lynch, Aamir Jeewa","doi":"10.3390/children12030306","DOIUrl":null,"url":null,"abstract":"<p><p>As early survival outcomes have improved, heart failure in children with congenital heart disease (CHD) has become a growing problem. Primary care providers and pediatricians are thus encountering increasing numbers of children with or at-risk for heart failure. Despite medication, many of these children progress to end-stage heart failure and require heart transplant for long-term survival. Mechanical circulatory support (MCS) is increasingly utilized to support this cohort both acutely when recovery is anticipated, and as a bridge to transplant. Early referral to tertiary heart failure and MCS teams is key to facilitate timely institution of MCS and preserve end-organ function. MCS in children with CHD presents unique challenges due to patient size and complex intra- and extra-cardiac anatomy. Evaluations for MCS should take into account patient size, anatomy, end-organ function, and psychosocial supports. The form of MCS utilized is dependent on clinical urgency, patient size, and anatomy. We describe the evolving landscape of MCS in pediatric patients with CHD.</p>","PeriodicalId":48588,"journal":{"name":"Children-Basel","volume":"12 3","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11941418/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Children-Basel","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/children12030306","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
As early survival outcomes have improved, heart failure in children with congenital heart disease (CHD) has become a growing problem. Primary care providers and pediatricians are thus encountering increasing numbers of children with or at-risk for heart failure. Despite medication, many of these children progress to end-stage heart failure and require heart transplant for long-term survival. Mechanical circulatory support (MCS) is increasingly utilized to support this cohort both acutely when recovery is anticipated, and as a bridge to transplant. Early referral to tertiary heart failure and MCS teams is key to facilitate timely institution of MCS and preserve end-organ function. MCS in children with CHD presents unique challenges due to patient size and complex intra- and extra-cardiac anatomy. Evaluations for MCS should take into account patient size, anatomy, end-organ function, and psychosocial supports. The form of MCS utilized is dependent on clinical urgency, patient size, and anatomy. We describe the evolving landscape of MCS in pediatric patients with CHD.
期刊介绍:
Children is an international, open access journal dedicated to a streamlined, yet scientifically rigorous, dissemination of peer-reviewed science related to childhood health and disease in developed and developing countries.
The publication focuses on sharing clinical, epidemiological and translational science relevant to children’s health. Moreover, the primary goals of the publication are to highlight under‑represented pediatric disciplines, to emphasize interdisciplinary research and to disseminate advances in knowledge in global child health. In addition to original research, the journal publishes expert editorials and commentaries, clinical case reports, and insightful communications reflecting the latest developments in pediatric medicine. By publishing meritorious articles as soon as the editorial review process is completed, rather than at predefined intervals, Children also permits rapid open access sharing of new information, allowing us to reach the broadest audience in the most expedient fashion.