Borderline Personality Disorder and Emotion Dysregulation最新文献

{"title":"Mentalization as a mediator of the effects of early life stress on borderline personality disorder in a South Korean clinical sample.","authors":"You Sun Chung, HyunKyung Shin, Bon-Hoon Koo, Seokho Yun, Uk-Jin Oh, Sun-Woo Choi, Bokyung Choo, Jeong-Ho Seok","doi":"10.1186/s40479-026-00338-2","DOIUrl":"10.1186/s40479-026-00338-2","url":null,"abstract":"<p><p>BACKGROUND: Borderline Personality Disorder (BPD) is a severe mental condition characterized by instability in self-image, emotions, and interpersonal relationships. Within mentalization models of BPD, the interaction between genetic vulnerabilities and early attachment-related adversity is understood to hinder the development of mentalization, contributing to core BPD symptoms. This study investigated early life stress (ELS) and mentalization difficulties in a Korean BPD sample and tested whether mentalization difficulties mediated their associations with BPD diagnosis and symptom severity. METHODS: We conducted a cross-sectional study with 90 individuals with BPD and 47 healthy controls using self-report measures of ELS, mentalization difficulties, and BPD symptoms. Group differences were examined, and a mediation model was tested using the PROCESS Macro. RESULTS: The BPD group showed higher levels of ELS across all domains and higher levels of most mentalization difficulties, with the exception of hasty mentalizing. Emotional abuse and bullying were associated with BPD diagnosis. Psychic equivalence and lack of emotional expression were associated with diagnosis, while psychic equivalence and lack of emotional awareness were associated with symptom severity. Mentalization difficulties partially mediated the links between ELS and both BPD diagnosis and symptom severity. CONCLUSIONS: Preventive efforts targeting emotional abuse and bullying, along with interventions to address mentalization difficulties, may help inform preventive strategies and improve treatment outcomes. Results support the need for mentalization-based interventions for individuals with BPD in Asian populations. </p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13159255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiences in close relationships, interpersonal trust and OXTR expression in individuals with childhood maltreatment.","authors":"Inga Niedtfeld, Marie Kolar Née Hofmann, Johanna Hepp, Sara E Schmitz, Sylvia Steinmann, Stephanie H Witt","doi":"10.1186/s40479-026-00340-8","DOIUrl":"10.1186/s40479-026-00340-8","url":null,"abstract":"<p><p>BACKGROUND: Social cognition is essential for forming and maintaining intimate relationships. Individuals with a history of childhood maltreatment (CM) often show impairments in interpersonal functioning, including trust and romantic attachment. The oxytocin system has been implicated in social behavior, yet the role of oxytocin receptor (OXTR) gene expression in CM-related social functioning remains insufficiently understood. This study examined the impact of CM on social cognition in a large web-based sample and explored the association between CM and OXTR gene expression in a well-characterized clinical cohort. METHODS: Both studies were preregistered ( https://doi.org/10.17605/OSF.IO/KNC2X ), and data and code are available at OSF ( https://doi.org/10.17605/OSF.IO/4DZWK ). Study 1 assessed the relationship between CM severity, interpersonal trust, and romantic attachment in a web-based sample (N = 252). Participants completed the Childhood Trauma Questionnaire, the Generalized Trust Scale, a behavioral distrust game, and the Experiences in Close Relationships Questionnaire. Study 2 analyzed OXTR gene expression in peripheral blood samples from N = 92 CM-exposed individuals and examined associations with self-reported CM severity. Exploratory analyses additionally included measures of interpersonal sensitivity, social functioning, and maladaptive personality traits. RESULTS: In Study 1, greater CM severity was significantly associated with lower interpersonal trust (both self-reported and behavioral), and with higher levels of attachment-related anxiety and avoidance. In Study 2, no significant association was found between CM severity and OXTR gene expression in blood. However, exploratory analyses revealed that CM severity was associated with social interaction difficulties, while OXTR gene expression was associated with the maladaptive personality trait of detachment. CONCLUSIONS: The findings highlight robust associations between CM and impairments in trust as well as insecure romantic attachment. Although no direct link was found between CM and OXTR expression, future research should investigate gene–environment interactions using larger samples and alternative tissue sources. Interventions targeting trust and attachment processes may offer promising avenues to improve relational functioning in individuals with a history of CM. </p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13063755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating a brief MBCT programme for non-suicidal self-injury in individuals with BPD: a within-subject pre-post pilot study.","authors":"Szilvia Kresznerits, Ágnes Zinner-Gérecz, Mónika Miklósi, Tamás Szekeres, Dóra Perczel-Forintos","doi":"10.1186/s40479-026-00337-3","DOIUrl":"10.1186/s40479-026-00337-3","url":null,"abstract":"<p><p>BACKGROUND: Non-suicidal self-injury (NSSI) is highly prevalent among individuals with borderline personality disorder (BPD) and a robust predictor of future suicide attempts and death. Access to comprehensive treatments such as dialectical behaviour therapy remains limited. METHODS: This exploratory study evaluated the feasibility and preliminary outcomes of a brief, group-based mindfulness-based cognitive therapy program tailored to reduce NSSI (MBCT-NSSI) and improve associated psychological processes. Using a nonrandomised within-subject pre–post design with a waiting-period comparison, assessments were conducted at baseline (T1; n = 120), pre-intervention (T2; n = 72), and post-intervention (T3; n = 50). Outpatients with BPD and recent NSSI participated in a 9-week MBCT-NSSI group programme; key exclusions were acute suicide risk, psychosis, mania, and severe substance use. Primary outcomes were NSSI frequency and mindfulness. Secondary outcomes included self-compassion, self-esteem, impulsivity, depression, dissociation, and emotion regulation. Within-subject changes were analysed via linear mixed modelling and Wilcoxon signed-rank tests. Binary logistic regression identified predictors of dropout among eligible participants. No blinding or randomisation procedures were applied. RESULTS: Among completers (N = 50), primary outcomes showed a significant reduction in NSSI frequency and an increase in mindfulness. Improvements were also observed across several secondary outcomes, including depressive symptoms, impulsivity, and emotion regulation. For mindfulness and secondary self-report outcomes, changes were observed between T2 and T3 but not during the waiting-list period. For NSSI, which was evaluated only at T1 and T3, findings should be interpreted as preliminary signal detection. Dissociative symptoms showed a non-significant trend toward improvement. Dropout among eligible patients was associated with higher impulsivity, maladaptive regulation, and, unexpectedly, higher self-compassion, whereas fewer comorbid diagnoses predicted lower treatment retention. CONCLUSIONS: MBCT-NSSI may be a feasible and potentially beneficial adjunctive intervention for individuals with BPD who engage in NSSI, with improvements in emotion regulation and preliminary signals of reduced self-harm frequency. These findings support further investigation through controlled trials and longer follow-up. TRIAL REGISTRATION: Not applicable. The study had a within-subject pre–post design without a control condition, and therefore does not meet the ICMJE definition of a clinical trial. De-identified data are openly available via the Open Science Framework (OSF): https://doi.org/10.17605/OSF.IO/ZUR84 . </p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13085490/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147390961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fluctuations of dissociation and inner tension during inpatient dialectical behavior therapy: associations with self-injury and suicidal ideation.","authors":"Ana Macchia, Dimitri Löchner, Christian Montag, Philip Santangelo, Michelle Voit, Simon Sanwald, Birgit Abler","doi":"10.1186/s40479-026-00339-1","DOIUrl":"10.1186/s40479-026-00339-1","url":null,"abstract":"<p><p>BACKGROUND: In Dialectical Behavior Therapy (DBT), monitoring inner tension and state dissociation is considered helpful for understanding a patient’s affective and behavioral responses, especially regarding self-harming behaviors. This study aims to investigate how potentially aversive internal states including dissociation, inner tension and fluctuations of tension, i.e. affective instability, during the initial phase of inpatient DBT relate to self-injury, suicidal ideation, and symptom reduction. METHODS: 41 patients with personality disorder (borderline or combined), undergoing an 8-week inpatient DBT program used a smartphone application for ecological momentary assessment of inner tension and state dissociation. We assessed the Borderline Symptom List (BSL-23) upon admission and discharge, self-injury during the inpatient stay, and the intensity of suicidal ideation per day (diary card ratings) retrospectively from digital patient files. We employed linear mixed models to analyze the trajectories of inner tension, affective instability (i.e. squared difference between consecutive inner tension ratings), and state dissociation over the initial 3 weeks of therapy and variability across hours, as well as daily associations with the intensity of suicidal ideation. We used logistic regression to examine if aversive internal states are associated with the occurrence of self-injury during DBT. RESULTS: We found a slight reduction in state dissociation, affective instability, and high levels of inner tension during the initial 3 weeks of therapy. Analyses of intraday data showed a slight increase in state dissociation from morning to midday and self-injury during DBT was associated with slightly higher mean dissociation levels. On days with greater intensity of suicidal ideation, elevated inner tension and state dissociation levels were found while affective instability was not related to self-injury or suicidal ideation. Changes in BSL-23 over therapy were not related to aversive internal states during the initial therapy phase. CONCLUSION: Aversive internal states decreased early in inpatient DBT, with midday emerging as a critical time for dissociation management. Daily increases in state dissociation and inner tension might serve as warning signs for suicidality and our data confirm the utility of their monitoring in self-harm prevention. When state dissociation is therapeutically addressed during DBT as in the program investigated, it does not seem to hamper improvement in borderline symptoms. TRIAL REGISTRATION: Retrospectively registered - https://osf.io/dfq9y/?view_only=4c19b891bb6448009b22f60b2552bd73 . </p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13064321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147370558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathology of the self: a network analysis of personality functioning, narcissistic vulnerability, mentalizing, and epistemic trust across trauma profiles.","authors":"Ilaria Maria Antonietta Benzi, Andrea Fontana, Nicola Carone, Francesca Locati, Laura Parolin, Karin Ensink","doi":"10.1186/s40479-026-00335-5","DOIUrl":"10.1186/s40479-026-00335-5","url":null,"abstract":"<p><p>BACKGROUND: Trauma exposure impairs personality functioning, mentalizing, and epistemic trust, yet the mechanisms linking these processes remain unclear. METHODS: Using network analysis, we examined how narcissistic traits, personality functioning, reflective functioning, and epistemic stances interact across trauma profiles in emerging adults (N = 1,081; 72.4% female). Participants completed the Childhood Trauma Questionnaire–Short Form (CTQ-SF), Levels of Personality Functioning Scale–Brief Form (LPFS-BF), Pathological Narcissism Inventory (PNI), Reflective Functioning Questionnaire for Youth (RFQY-13), and Epistemic Trust, Mistrust, and Credulity Questionnaire (ETMCQ). Latent profile analysis identified three trauma profiles: low trauma, emotional trauma, and complex trauma. RESULTS: For all three trauma profiles, narcissistic vulnerability and self-impairment formed a stable, central dyad, indicating a core of transdiagnostic dysfunction. Trauma exposure was associated with denser, more interconnected networks, likely reflecting self-reinforcing maladaptive patterns. Uncertainty about mental states emerged as the primary bridge mechanism, increasing with trauma severity and transmitting dysfunction into epistemic stances. Trauma was associated with both mistrust and credulity—mistrust predominated in emotional trauma, credulity in complex trauma. CONCLUSIONS: These findings delineate common and trauma-specific processes linking personality dysfunction and interpersonal traits. Clinically, they highlight the importance of addressing narcissistic vulnerability and self-functioning as stable mechanisms, reducing uncertainty through mentalization-based interventions, and tailoring treatment to trauma-specific epistemic patterns. </p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13005497/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146182904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How specific are affective and attachment instability to adolescents with non-suicidal self-injury? A comparison with adolescents with major depression.","authors":"Annekatrin Steinhoff, Julian Koenig, Julia Blanke, Philip Santangelo, Ulrich Ebner-Priemer, Michael Kaess","doi":"10.1186/s40479-026-00336-4","DOIUrl":"10.1186/s40479-026-00336-4","url":null,"abstract":"<p><p>BACKGROUND: Affective and interpersonal instability are suggested to underlie adolescent non-suicidal self-injury (NSSI). However, previous research has not directly compared adolescents with NSSI to those with psychiatric conditions that are often, but not always, correlated with NSSI. We explored the specificity of affective and interpersonal instability to adolescent NSSI compared to depression. METHODS: Based on a clinical sample of 70 adolescents (56 female and 14 male), we compared a group with NSSI (n = 50) with a clinical comparison group diagnosed with major depression and no engagement in NSSI (n = 20). We used high-frequency ecological momentary assessments (EMA) of affect and interpersonal attachment over four days. Mean affect and mean attachment as well as the root mean squares of successive differences (RMSSD) indicating instability of affect and attachment were calculated. The groups were compared using regression modeling. RESULTS: Adolescents with NSSI reported less positive affect and lower levels of attachment to their mothers and best friends than those with depression. Moreover, models adjusting for gender and mean affect and attachment, respectively, indicated that the NSSI group experienced more affective instability (b = 6.26, 95% CI = 0.79—11.73, p = 0.025). The two groups experienced similar average levels of attachment instability. Although there was no moderating effect of gender in the reported associations, the link between affective instability and NSSI was mainly driven by the male subsample, whereas low levels of attachment were associated with NSSI especially in females. CONCLUSIONS: Affective instability is especially high among adolescents with NSSI. When co-occurring with other disorders, NSSI may serve as an identifier of a patient’s particularly strong need for treatment aiming at affect stabilization. </p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12997848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146182858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimating and learning personality traits of and from women with borderline personality disorder.","authors":"Lisa M Doppelhofer, Raphael Perla, Koen M M Frolichs, Gabriela Rosenblau, Sabine C Herpertz, Christoph W Korn","doi":"10.1186/s40479-025-00320-4","DOIUrl":"10.1186/s40479-025-00320-4","url":null,"abstract":"<p><p>BACKGROUND: Accurately perceiving and learning about others’ personalities is crucial for successful social relationships. Borderline Personality Disorder (BPD) is marked by unstable interpersonal dynamics, an unstable and negative self-concept, and a tendency to evaluate others unfavorably. Individuals with BPD are also more likely to be viewed negatively by others and experience social stigmatization. This study investigated whether women with BPD exhibit negativity biases when evaluating their own and others’ personality traits, and how these biases influence learning about others. METHODS: Thirty women with BPD and thirty-one age- and intelligence-matched controls estimated and learned the personality of six individuals (learning profiles) by predicting their self-ratings on 40 personality traits, balanced across the Big Five personality dimensions. After each prediction, participants received feedback with the target’s actual rating, allowing participants to gradually learn each profile’s personality. Three profiles reflected BPD group personality patterns and three profiles reflected control group patterns. Crucially, participants were told that these profiles were from real individuals but were unaware of their clinical status. RESULTS: As hypothesized, the BPD group rated themselves more negatively than controls, both at the trait level and on standardized personality measures (NEO-FFI, PID-5-BF). When evaluating others, both groups rated BPD profiles similarly, but the control group rated control profiles more favorably. For both groups, accuracy improved slightly over time for control profiles but not BPD profiles, suggesting that BPD trait patterns are inherently harder to learn. Computational modeling indicated that both groups used fine-grained learning strategies—regardless of profile type—with no credible group differences in learning mechanisms. CONCLUSION: These findings demonstrate that individuals with BPD exhibit pervasive negativity biases in self- and other-evaluations, yet retain intact social learning capacities. This suggests that interpersonal difficulties in BPD may stem more from negatively biased expectations than from deficits in learning. Moreover, the inherent difficulty in learning about BPD-like personality profiles—observed in both groups—may hinder mutual understanding and contribute to persistent social challenges. Importantly, the intact learning capacity points to a valuable therapeutic resource: targeting negative social expectations may help to reduce bias and improve social functioning in BPD. </p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"13 1","pages":"5"},"PeriodicalIF":3.2,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12888613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146151134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attachment orientations and borderline personality features: the mediating role of difficulties in interpersonal emotion regulation.","authors":"Irene Messina, Pietro Spataro, Giulia Gagliardini, Tatiana Rossi, Alessandro Grecucci","doi":"10.1186/s40479-025-00323-1","DOIUrl":"10.1186/s40479-025-00323-1","url":null,"abstract":"<p><p>BACKGROUND: Insecure attachment predicts borderline personality (BP), with emotion regulation widely recognized as a key mediator of this association. While interpersonal difficulties are central to BP, most studies have focused on intrapersonal emotion regulation, overlooking its interpersonal forms. Given the importance of understanding emotional and relational dysfunctions in BP, this study examined difficulties in Interpersonal Emotion Regulation (IER), investigating the role of maladaptive strategies—venting and excessive reassurance-seeking—as mediators in the relationship between attachment insecurity and BP. METHODS: A total of 420 adults completed self-report measures assessing BP features (PAI-BOR: affective instability, identity disturbances, negative relationships, and self-harm), attachment orientations (ECR-12: attachment anxiety and attachment avoidance), and IER difficulties (DIRE: venting and reassurance-seeking). Pearson’s correlations tested associations among variables, and a path analysis was conducted, using attachment anxiety and avoidance as exogenous variables, IER difficulties as mediators, and BP features as outcome variables. RESULTS: Attachment anxiety was positively associated with all BP features and greater difficulties in IER (venting and reassurance-seeking). IER mediated the relationship between attachment anxiety and BP features, with venting significantly mediating all BP dimensions. CONCLUSIONS: Findings highlight a self-perpetuating cycle of relational difficulties and emotional dysregulation in BP, with IER playing a crucial role. Excessive reliance on others for emotional regulation, likely stemming from mentalization impairments, may lead individuals with BP and anxious attachment to externalize distress, reinforcing negative moods and straining relationships. Psychological interventions should focus on breaking this cycle by enhancing emotion regulation abilities, fostering autonomy, and reducing maladaptive dependence on others for emotional relief. </p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"13 1","pages":"4"},"PeriodicalIF":3.2,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12874987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146127043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric properties of the Level of Personality Functioning Scale- Brief Form 2.0 (LPFS-BF 2.0) in women with attention-deficit/hyperactivity disorder.","authors":"Dara E Babinski, Daniel A Waschbusch","doi":"10.1186/s40479-025-00334-y","DOIUrl":"10.1186/s40479-025-00334-y","url":null,"abstract":"<p><strong>Background: </strong>Women with attention-deficit/hyperactivity disorder (ADHD) are also often diagnosed with personality disorders, yet research on reliable and valid assessments of personality pathology in this population has been limited.</p><p><strong>Methods: </strong>In this study, the psychometric properties of the Level of Personality Functioning Scale- Brief Form - 2.0 (LPFS-BF 2.0) were examined in a sample of 171 adult women with ADHD.</p><p><strong>Results: </strong>A two-factor structure was identified, with one factor, LPF-self, comprised of six items, reflecting impairment in self functioning; the second factor, LPF-interpersonal, comprised of six items, reflecting impairment in interpersonal functioning. LPFS-BF 2.0 factors contributed unique variance to functional impairment beyond the effects of co-occurring depression, anxiety, and ADHD.</p><p><strong>Conclusions: </strong>These findings suggest the LPFS-BF 2.0 may be important to include in clinical care for women with ADHD, to identify those women with ADHD who may require adjunctive intervention for personality pathology.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":"1"},"PeriodicalIF":2.7,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12829034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145918865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A laboratory task to assess epistemic mistrust: behavioral evidence for mediation between childhood trauma and borderline personality features in young adults.","authors":"Elizabeth Li, Chloe Campbell, Linda C Mayes, Georgia McRedmond, Patrick Luyten","doi":"10.1186/s40479-025-00333-z","DOIUrl":"10.1186/s40479-025-00333-z","url":null,"abstract":"<p><strong>Background: </strong>Disruptions in epistemic trust have been recognised as key sequelae of trauma and as markers of vulnerability to borderline personality pathology. However, prior research has relied primarily on self-reports and lacks behavioural measures of epistemic stance. The present pre-registered studies introduce a novel behavioural task-the Balloon Analogue Risk Task for Epistemic Trust (BART-ET)-and examine its associations with borderline personality features, trauma history, and psychological distress.</p><p><strong>Methods: </strong>Two cross-sectional studies were conducted with a combined sample of 273 young adults aged 18-25 (Study 1: N = 120; Study 2: N = 153). Participants completed self-report measures of borderline personality features (PAI-BOR) and epistemic trust, mistrust, and credulity (ETMCQ). Study 2 additionally included the Childhood Trauma Questionnaire (CTQ) and the Brief Symptom Inventory (BSI-GSI). All participants completed the BART-ET in a laboratory setting, which operationalised epistemic mistrust as the degree of deviation from a confederate experimenter's advice during a risk-taking task. Analyses involved correlational tests and structural equation modelling (SEM) to evaluate hypothesised associations and mediation pathways.</p><p><strong>Results: </strong>As expected, across both studies, higher levels of borderline personality traits were associated with greater epistemic mistrust-both behaviourally (on the BART-ET) and via self-report (ETMCQ)-and with greater epistemic credulity, but not with epistemic trust, as measured with the ETMCQ. Behavioural and self-report measures of mistrust were significantly correlated, suggesting convergent validity of the BART-ET as an index of epistemic mistrust. In Study 2, childhood trauma exposure was associated with borderline features and with epistemic mistrust assessed behaviourally and via self-report. Preregistered mediation models controlling for general distress (BSI-GSI) suggested that the association between childhood trauma and epistemic mistrust was not unique to BPD features.</p><p><strong>Conclusions: </strong>These findings suggest that epistemic mistrust-rather than a simple absence of trust-is a social-cognitive correlate of borderline personality vulnerability and trauma exposure in young adults. The results also indicate that the BART-ET may be a useful behavioural tool for studying epistemic mistrust in clinical contexts, though further validation is needed.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":"2"},"PeriodicalIF":2.7,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12853794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145844429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}