Kristine Høst Poulsen, Carsten Hjorthøj, Bo Bach, Erik Simonsen, Mickey T Kongerslev
{"title":"Does changing clinicians' attitudes toward self-harm reduce coercive interventions in mental health inpatient settings? A quasi-experimental study of staff training.","authors":"Kristine Høst Poulsen, Carsten Hjorthøj, Bo Bach, Erik Simonsen, Mickey T Kongerslev","doi":"10.1186/s40479-026-00346-2","DOIUrl":"10.1186/s40479-026-00346-2","url":null,"abstract":"<p><strong>Background: </strong>Staff education may improve clinicians' attitudes toward self-harm, but whether this translates into reduced coercion is unclear. We evaluated a regional strategy to improve care for self-harming patients and its impact on staff attitudes and coercive interventions across services.</p><p><strong>Methods: </strong>Quasi-experimental dual design: (a) interrupted time-series of registry data on coercive interventions (Jan 2021-Dec 2024) and (b) three-wave pre-post surveys using the revised 17-item Self-Harm Antipathy Scale (SHAS-DR) at baseline, 2 months, and 8 months post-training. Change points: June 2022 (strategy announcement) and June 2023 (training implementation).</p><p><strong>Results: </strong>In registry data, coercive interventions declined after the strategy announcement (level IRR 0.39, 95% CI 0.21-0.73) with no subsequent trend change. A temporary increase occurred at the training point (level IRR 2.58, 95% CI 1.57-4.25), consistent with implementation disruption. Reductions were largest for mechanical restraints, particularly among self-harming patients, while rapid tranquillization remained most frequent. Annual coercive episodes fell from 1,280 (2021) to 409 (2024). Staff attitudes improved and were sustained. Mean SHAS-DR decreased from 40.0 (SD 10.8) at baseline to 34.8 (SD 7.4) at 2 months and 35.4 (SD 8.2) at 8 months; baseline-to-follow-up changes were significant (p ≤ 0.001).</p><p><strong>Conclusions: </strong>The strategy coincided with an immediate reduction in coercion and a transient rise during training, while staff attitudes reflected reduced antipathy toward people who self-harm. Sensitivity analyses suggested changes were not driven by high-frequency patients. Sustained reductions likely require continued organizational and relational supports.</p><p><strong>Trial registration: </strong>Not applicable.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"13 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13459957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148708152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giuseppe Guerriero, Anthony C Ruocco, Hanne K Carlsen, Alexander R Daros, Duaa Kosara, Steinn Steingrimsson
{"title":"Transcutaneous auricular vagus nerve stimulation and emotional responding in borderline personality disorder: a randomized single-blind, sham-controlled study.","authors":"Giuseppe Guerriero, Anthony C Ruocco, Hanne K Carlsen, Alexander R Daros, Duaa Kosara, Steinn Steingrimsson","doi":"10.1186/s40479-026-00367-x","DOIUrl":"10.1186/s40479-026-00367-x","url":null,"abstract":"<p><strong>Background: </strong>Borderline personality disorder (BPD) is characterized by severe emotional vulnerability, including heightened sensitivity, exaggerated reactivity, and delayed recovery from emotional arousal. Altered interoceptive-affective processing may contribute to these features. Transcutaneous auricular vagus nerve stimulation (taVNS) provides a non-invasive method for modulating vagal-afferent pathways involved in interoception and emotion regulation. This study examined whether active taVNS, relative to sham stimulation, was associated with lower self-reported negative affect during a video-based mood-induction paradigm in women with BPD.</p><p><strong>Methods: </strong>Thirty-four female psychiatric outpatients with DSM-5 BPD were randomized to receive active taVNS or sham stimulation during a single-session experimental paradigm. Self-reported negative affect was assessed repeatedly using the Positive and Negative Affect Schedule (PANAS) Negative Affect scale. The primary analysis modeled PANAS Negative Affect across four collapsed task phases: Pre-Induction, Post-Neutral, Post-Negative, and Recovery-Negative, adjusting for baseline negative affect and stimulation intensity. Exploratory physiological analyses examined heart rate, lnRMSSD, phasic electrodermal activity (EDA) response frequency, and tonic skin conductance level.</p><p><strong>Results: </strong>Active taVNS was associated with lower PANAS Negative Affect across the mood-induction paradigm compared with sham stimulation, Treatment Group: F(1, 36.44) = 5.74, p = 0.022. Negative affect varied significantly across task phases, F(3, 94.12) = 22.60, p < 0.001, confirming successful mood induction. The Treatment Group × Phase interaction was not significant, F(3, 94.12) = 0.75, p = 0.525. Exploratory physiological analyses showed no treatment-related effects on heart rate, lnRMSSD, or phasic EDA response frequency. Tonic skin conductance level showed no main effect of Treatment Group, but an exploratory Treatment Group × Epoch interaction.</p><p><strong>Conclusions: </strong>In this preliminary single-session randomized sham-controlled study, active taVNS was associated with lower self-reported negative affect during a mood-induction paradigm in women with BPD. This subjective effect was not accompanied by treatment-related effects on heart rate, lnRMSSD, or phasic EDA response frequency, while the tonic skin conductance interaction should be interpreted cautiously as exploratory. These findings support further investigation of taVNS as a mechanistic probe of acute affective responding in BPD.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov NCT05892900. Retrospectively registered 7 June 2023.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"13 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13435753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Max C Pensel, Johanna M H L Siems, Alexander Blazejak, Charlotte Steinau, Jana Fink, Marie-Therese Schmitz, Alexandra Philipsen, Henrik Rohner
{"title":"Dissociative symptoms during the SARS-CoV-2 pandemic situation in mental health patients.","authors":"Max C Pensel, Johanna M H L Siems, Alexander Blazejak, Charlotte Steinau, Jana Fink, Marie-Therese Schmitz, Alexandra Philipsen, Henrik Rohner","doi":"10.1186/s40479-026-00363-1","DOIUrl":"10.1186/s40479-026-00363-1","url":null,"abstract":"<p><strong>Background: </strong>Dissociative symptoms arise in reaction to significant stress and are common in post-traumatic stress disorder (PTSD).</p><p><strong>Methods: </strong>We longitudinally investigated the course of dissociative symptoms in psychiatric patients over the first year of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic situation (04/2020-05/2021). The group was separated into patients with relevant symptoms of PTSD at study start (Group 1: PTSDG) and those without (Group 2: noPTSDG), and we also employed a control group (Group 3: CG). Dissociative symptoms were tracked using the \"Fragebogen zu Dissoziativen Symptomen\" (FDS), an adapted and extended German version of the \"Dissociative Experience Scale\" (DES). Datasets of 93 participants were analyzed over up to three time periods. In addition, the regional incidence of positive SARS-CoV-2 tests (7di) and the intensity of non-pharmacological interventions (NPI) were included in multilevel linear models.</p><p><strong>Results: </strong>Patients reported stronger dissociative symptoms in the PTSDG than in the noPTSDG, while the CG showed the lowest symptom intensity. Importantly, regarding the course of symptoms over time, while public counts of positive SARS-CoV-2 tests had no influence, dissociative symptom severity was significantly impacted by the intensity of non-pharmacological interventions, particularly in the PTSDG and regarding depersonalization and derealization.</p><p><strong>Conclusion: </strong>Patients with relevant symptoms of PTSD at study start suffered from intense dissociative symptoms over the first year of the SARS-CoV-2 pandemic situation, driven by non-pharmacological interventions. In a milder way, other psychiatric patients were also affected. The results underline the responsivity of these patient groups regarding social and political stress.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"13 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13403852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148608852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José Blanco Machinea, Loris Grandjean, Hélène Beuchat, Stéphane Kolly, Philippe Conus, Yves de Roten, Jérémie André, Hervé Tissot, Ueli Kramer
{"title":"Follow-up effects of a brief Good Psychiatric Management treatment for borderline personality disorder.","authors":"José Blanco Machinea, Loris Grandjean, Hélène Beuchat, Stéphane Kolly, Philippe Conus, Yves de Roten, Jérémie André, Hervé Tissot, Ueli Kramer","doi":"10.1186/s40479-026-00357-z","DOIUrl":"https://doi.org/10.1186/s40479-026-00357-z","url":null,"abstract":"<p><strong>Background: </strong>Borderline personality disorder (BPD) is among the most frequent, debilitating, and lethal mental conditions. Treatment for patients with BPD involves structured psychotherapy, but such treatment is often not readily available due to imbalances in supply and demand for care. Brief treatments that are available as first-line interventions may address this delay in care. No controlled study has assessed the effectiveness of brief psychiatric interventions, such as 10 sessions of Good Psychiatric Management (GPM) over 12 months follow-up, in comparison with treatment as usual. Whereas most psychotherapy studies in patients with BPD focus on symptom reduction at the end of treatment, more research is needed on the patients' symptom levels after one year.</p><p><strong>Methods: </strong>The present study compares brief psychiatric treatment (4 months of GPM) with treatment as usual (4 months of TAU). Participants (N = 76 patients with BPD) undergo assessments at intake, after two months, at discharge (4 months) and 1 year follow-up (16 months after intake). At these four time-points, each patient was assessed using the clinician rated Zanarini BPD (ZAN-BPD) scale.</p><p><strong>Results: </strong>The study found brief GPM to show significantly greater symptom reduction in ZAN-BPD scores between intake of 4-month treatment and 12-month follow-up (16 months later), compared to treatment as usual.</p><p><strong>Conclusion: </strong>This study shows that after one year, the effects of a brief psychiatric treatment are strengthened in both groups. Additionally, brief GPM presents an advantage in helping BPD patients make further progress after the intervention has ended, which potentially helps diminish the societal burden of disease related to BPD symptomatology.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148457398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case study: The DBT implementation journey of dialectical behaviour therapy in five European countries.","authors":"Amy Gaglia Essletzbichler, Miriam Bierman, Magdalena Skuza, Natálie Češková, Anita Johanna Tørmoen","doi":"10.1186/s40479-026-00359-x","DOIUrl":"https://doi.org/10.1186/s40479-026-00359-x","url":null,"abstract":"<p><strong>Background: </strong>This paper is a narrative review of the implementation trajectories Dialectical Behaviour Therapy in five countries, the UK, Germany Norway, Poland, and the Czech Republic in Europe over the past 30 years. The aim of this comparison is to identify common and divergent systems levels facilitators and hindrances of DBT implementation.</p><p><strong>Methods: </strong>DBT experts in each respective country were asked to provide a narrative account of their country's implementation journey. Histories were then considered in accordance with existing DBT implementation frameworks.</p><p><strong>Results: </strong>Common themes emerged such as the importance national guidelines on evidence-based treatment shape implementation, university affiliations promote dissemination, implementation and research activities, national societies help to create standards.</p><p><strong>Conclusion: </strong>There are common DBT implementation trajectories that exist across geography and nationally specific mental health care systems. The discussion of the refining of national DBT practices based on emerging literature and the importance of outcomes of implementation such as therapists' behaviour or client related outcome data adds to existing information.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148450085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruben Vonderlin, Büsra Senyüz, Carola Claus, Saskia Mahalingam, Anna Schulze, Stefan Koch, Ulrich Voderholzer, Christian Schmahl, Jürgen Margraf, Tobias Teismann, Nikolaus Kleindienst, Tali Boritz, Shelley McMain, Martin Bohus, Stefanie Lis
{"title":"The role of different forms of adverse childhood experiences in borderline personality disorder: results from a network analysis including clinical and non-clinical populations.","authors":"Ruben Vonderlin, Büsra Senyüz, Carola Claus, Saskia Mahalingam, Anna Schulze, Stefan Koch, Ulrich Voderholzer, Christian Schmahl, Jürgen Margraf, Tobias Teismann, Nikolaus Kleindienst, Tali Boritz, Shelley McMain, Martin Bohus, Stefanie Lis","doi":"10.1186/s40479-026-00356-0","DOIUrl":"10.1186/s40479-026-00356-0","url":null,"abstract":"<p><strong>Background: </strong>Borderline Personality Disorder (BPD) has been associated with a range of adverse experiences, including emotional, physical, and sexual abuse, neglect, invalidation, bullying, and unpredictable environments during childhood and adolescence (ACE). While these different forms of ACE often co-occur, most research has examined them in isolation, leaving unclear their interrelations and specific significance for BPD psychopathology.</p><p><strong>Objective: </strong>This study investigates the level of different forms of ACE exposure in BPD and clinical controls, whether they are differentially related to the severity of BPD symptoms and how they are inter-related with each other.</p><p><strong>Methods: </strong>Cross-sectional data were collected from individuals diagnosed with BPD (n = 171), clinical controls (CC; n = 93), and non-clinical controls (NC; n = 73). BPD symptoms were measured using the BSL-23, while different types of ACE were assessed using the CTQ (abuse/neglect), ICES (invalidation), QUIC (unpredictability), and BSA (bullying). Graph-theoretical network analyses were conducted across groups to investigate associations between BPD symptom severity and ACE types, as well as interrelationships among ACEs. Data-driven community detection was applied to identify clusters of closely connected ACE types.</p><p><strong>Results: </strong>The BPD group showed higher ACE severity across all forms of ACE compared to CC and NC groups. Network analysis revealed unique associations between BPD symptom severity and emotional abuse, peer bullying, parental unpredictability, and lack of safety and security. Examination of interrelationships among ACE types resulted in a five-cluster solution demonstrating a complex pattern of unique associations.</p><p><strong>Conclusions: </strong>This study advances our understanding of how different forms of ACE relate to BPD psychopathology and how they are interrelated with each other. The findings suggest that the impact of ACE extends beyond physical and sexual abuse to include relational and environmental adversities with relevance for BPD symptom severity in adulthood.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"13 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13371558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148449781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pascal Louis, Simon Rigoulot, Dominick Gamache, Audrey Bernier, Justine Le Blanc-Brillon, Claudia Savard, Sébastien Hétu
{"title":"Borderline personality symptom severity predicts reduced mentalization and affective empathy and altered responses to fairness in the Ultimatum Game.","authors":"Pascal Louis, Simon Rigoulot, Dominick Gamache, Audrey Bernier, Justine Le Blanc-Brillon, Claudia Savard, Sébastien Hétu","doi":"10.1186/s40479-026-00358-y","DOIUrl":"https://doi.org/10.1186/s40479-026-00358-y","url":null,"abstract":"<p><strong>Background: </strong>Borderline personality (BP) symptoms are characterized by emotional instability, impulsivity, and interpersonal difficulties. Deficits in mentalization (ability to attribute mental states to self and others) and affective empathy (congruent and incongruent emotional reactions), may contribute to these social impairments. This study investigated whether, in a community sample, mentalization and affective empathy mediate the relationship between BP symptom severity and altered social decision-making in the Ultimatum Game (UG), where participants were asked to accept/reject fair and unfair monetary offers from Proposers displaying various emotional facial expressions (happy, angry, neutral).</p><p><strong>Methods: </strong>A community sample of 111 participants completed a measure of BP symptom severity, a dispositional mentalization/affective empathy questionnaire, an emotion recognition task to assess behavioral mentalization, and played the role of Responders in the UG. Relations between BP symptom severity and mentalization and affective empathy measures were tested using hierarchical regressions. Social decision-making was analyzed using multilevel logistic regression models examining the effects of fairness, emotion, and BP symptom severity on acceptance decisions. The potential mediating role of mentalization and affective empathy was evaluated using multilevel mediation analyses.</p><p><strong>Results: </strong>Higher BP symptom severity was significantly associated with poorer dispositional affective empathy (on both resonance and dissonance scores). Higher BP symptom severity was also associated with lower dispositional mentalization and impaired behavioral mentalization, especially for the recognition of happiness and anger. In the UG, BP symptom severity interacted with fairness of the offer: individuals with higher BP symptom severity were less likely to accept fair offers, whereas acceptance of unfair offers did not differ as a function of symptom severity. BP symptom severity was not associated with differential sensitivity to Proposers' emotional expressions. Preliminary analyses indicated that mentalization and affective empathy were not associated with behavioral responses in the UG; therefore, mediation analyses were not conducted.</p><p><strong>Conclusions: </strong>Findings highlight mentalization and affective empathy impairments as important elements of BP symptomatology. However, altered social decision-making associated with BP symptoms appears to be specific to responses to fairness rather than to emotional expressions per se. Further research in clinical populations is needed to clarify the mechanisms underlying these interpersonal decision-making patterns.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148413371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HyunKyung Shin, Wonjun Choi, You Sun Chung, Haein Park, Uk-Jin Oh, Sun-Woo Choi, Ju-Yeal Lee, Seokho Yun, Bokyung Choo, Bon-Hoon Koo, Jeong-Ho Seok
{"title":"A pilot randomized controlled trial of mentalization-based treatment and structured clinical management for outpatients with borderline personality disorder in South Korea.","authors":"HyunKyung Shin, Wonjun Choi, You Sun Chung, Haein Park, Uk-Jin Oh, Sun-Woo Choi, Ju-Yeal Lee, Seokho Yun, Bokyung Choo, Bon-Hoon Koo, Jeong-Ho Seok","doi":"10.1186/s40479-026-00354-2","DOIUrl":"https://doi.org/10.1186/s40479-026-00354-2","url":null,"abstract":"<p><strong>Background: </strong>To evaluate the effectiveness of mentalization-based treatment (MBT) for borderline personality disorder (BPD) compared to structured clinical management (SCM) in a South Korean clinical setting.</p><p><strong>Methods: </strong>This single-blind pilot randomized controlled trial included 64 individuals with a primary diagnosis of BPD who underwent either MBT (n = 37) or SCM (n = 27) in an outpatient setting over 12 months. Both interventions included weekly individual and group sessions. The primary outcome measure was the number of suicide attempts. Secondary outcomes included depressive symptoms, suicide risk, hospitalization frequency and duration, mentalization difficulties, adult attachment styles, BPD symptom severity, and resilience. Outcomes were assessed at baseline and 6 and 12 months. Analyses were conducted using generalized estimating equations, following the intention-to-treat principle.</p><p><strong>Results: </strong>Both treatment groups demonstrated a significant reduction in suicide attempts over 12 months, with no significant between-group differences in the primary outcome. However, participants receiving MBT showed consistent and sustained improvements in depressive symptoms, mentalization difficulties, and resilience. MBT was also associated with a significant reduction in attachment anxiety at 12 months, whereas the SCM produced earlier reductions in suicide risk and improvements in psychic equivalence. No significant changes were observed in attachment avoidance or in the hasty and incomplete mentalizing domains in either group.</p><p><strong>Conclusions: </strong>This pilot trial provides preliminary evidence that both MBT and SCM were effective in reducing suicidal behaviors and enhancing psychological functioning among Koreans with BPD. MBT demonstrated greater long-term benefits in emotion regulation and adaptability, suggesting that it may serve as a culturally scalable intervention in non-Western clinical settings.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148413421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nora M Laskowski, Hannah R Hambruch, Isa Häkkinen, Iris Pollmann, Claudia M Deutschmann, Gerrit Brandt, Cristina Ballero Reque, Georgios Paslakis
{"title":"Which EDE-Q items are structurally relevant in borderline personality disorder? An exploratory graph analysis.","authors":"Nora M Laskowski, Hannah R Hambruch, Isa Häkkinen, Iris Pollmann, Claudia M Deutschmann, Gerrit Brandt, Cristina Ballero Reque, Georgios Paslakis","doi":"10.1186/s40479-026-00355-1","DOIUrl":"10.1186/s40479-026-00355-1","url":null,"abstract":"<p><strong>Background: </strong>Borderline personality disorder (BPD) frequently co-occurs with eating disorders (EDs). Despite this clinical relevance, the dimensional structure of commonly used assessment instruments, such as the Eating Disorder Examination Questionnaire (EDE-Q), has not been sufficiently examined in BPD populations. Previous research suggests that the original four-factor structure of the EDE-Q may not be stable across different populations.</p><p><strong>Methods: </strong>This study examined the structure of the EDE-Q in a clinical sample of individuals with BPD (N = 73) using Exploratory Graph Analysis (EGA), a network-based approach to dimensionality assessment. Dimensionality and item stability were evaluated using nonparametric bootstrapping. Robustness was assessed via sensitivity analyses, including median imputation, variation of the regularization parameter, comparison of community detection algorithms, and leave-one-item-out procedures.</p><p><strong>Results: </strong>After iterative item reduction, a three-dimensional solution emerged, comprising 13 items. The identified dimensions reflected (1) Restraint, (2) Cognitive-Interpersonal Eating Concerns, and (3) Body Dissatisfaction. The final solution demonstrated high robustness across all sensitivity analyses, with identical dimensional structures and item assignments under multiple conditions.</p><p><strong>Conclusions: </strong>The findings suggest that the original four-factor structure of the EDE-Q may not fully generalize to individuals with BPD. Several aspects of the identified structure are consistent with previous research reporting deviations from the original EDE-Q model. These findings underscore the importance of validating assessment instruments within specific clinical populations and support a cautious interpretation of standard EDE-Q subscale scores in individuals with BPD.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"13 1","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13317289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jose H Marco-Salvador, Sandra Perez-Rodriguez, Laura Diaz-Sanahuja, Antonio Grau, Macarena Paredes-Mealla, Verónica Guillen
{"title":"Dialectical behavioral therapy-based skills training program for family members of suicide attempters: a randomized controlled trial.","authors":"Jose H Marco-Salvador, Sandra Perez-Rodriguez, Laura Diaz-Sanahuja, Antonio Grau, Macarena Paredes-Mealla, Verónica Guillen","doi":"10.1186/s40479-026-00353-3","DOIUrl":"https://doi.org/10.1186/s40479-026-00353-3","url":null,"abstract":"<p><strong>Background: </strong>Family members of individuals who have attempted suicide may experience feelings of guilt, depression, hopelessness, and burnout. Previous studies suggest that Psychoeducational Interventions (PI) for caregivers of people with suicide attempts improve their feelings of caregiver burden and that Dialectical Behavioral Therapy (DBT) helps to reduce caregivers' burden, depression, and validating behaviors. However, no studies have analyzed whether DBT is more effective than PI for caregivers of people who have made suicide attempts.</p><p><strong>Methods: </strong>The aim of the study was to analyze the differential efficacy of the DBT vs. PI. The study was a superiority trial with a two-arm randomized controlled design. The intention-to-treat principle was employed using mixed-effects models. In all, 108 caregivers of patients diagnosed with Suicide Behavior Disorder were randomized.</p><p><strong>Results: </strong>DBT was equally effective as PI in alleviating caregivers' burden. DBT was more effective than PI in increasing caregivers´ family empowerment and validation behaviors and reducing stress.</p><p><strong>Conclusions: </strong>This study suggests that DBT could be an effective intervention for caregivers of people with suicide attempts.</p><p><strong>Trial registration: </strong>The study was registered on December 15, 2021 in https://www.</p><p><strong>Clinicaltrials: </strong>gov/ ID: NCT05157607.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148253739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}