Borderline Personality Disorder and Emotion Dysregulation最新文献

{"title":"Estimating and learning personality traits of and from women with borderline personality disorder.","authors":"Lisa M Doppelhofer, Raphael Perla, Koen M M Frolichs, Gabriela Rosenblau, Sabine C Herpertz, Christoph W Korn","doi":"10.1186/s40479-025-00320-4","DOIUrl":"10.1186/s40479-025-00320-4","url":null,"abstract":"<p><p>BACKGROUND: Accurately perceiving and learning about others’ personalities is crucial for successful social relationships. Borderline Personality Disorder (BPD) is marked by unstable interpersonal dynamics, an unstable and negative self-concept, and a tendency to evaluate others unfavorably. Individuals with BPD are also more likely to be viewed negatively by others and experience social stigmatization. This study investigated whether women with BPD exhibit negativity biases when evaluating their own and others’ personality traits, and how these biases influence learning about others. METHODS: Thirty women with BPD and thirty-one age- and intelligence-matched controls estimated and learned the personality of six individuals (learning profiles) by predicting their self-ratings on 40 personality traits, balanced across the Big Five personality dimensions. After each prediction, participants received feedback with the target’s actual rating, allowing participants to gradually learn each profile’s personality. Three profiles reflected BPD group personality patterns and three profiles reflected control group patterns. Crucially, participants were told that these profiles were from real individuals but were unaware of their clinical status. RESULTS: As hypothesized, the BPD group rated themselves more negatively than controls, both at the trait level and on standardized personality measures (NEO-FFI, PID-5-BF). When evaluating others, both groups rated BPD profiles similarly, but the control group rated control profiles more favorably. For both groups, accuracy improved slightly over time for control profiles but not BPD profiles, suggesting that BPD trait patterns are inherently harder to learn. Computational modeling indicated that both groups used fine-grained learning strategies—regardless of profile type—with no credible group differences in learning mechanisms. CONCLUSION: These findings demonstrate that individuals with BPD exhibit pervasive negativity biases in self- and other-evaluations, yet retain intact social learning capacities. This suggests that interpersonal difficulties in BPD may stem more from negatively biased expectations than from deficits in learning. Moreover, the inherent difficulty in learning about BPD-like personality profiles—observed in both groups—may hinder mutual understanding and contribute to persistent social challenges. Importantly, the intact learning capacity points to a valuable therapeutic resource: targeting negative social expectations may help to reduce bias and improve social functioning in BPD. </p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"13 1","pages":"5"},"PeriodicalIF":3.2,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12888613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146151134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attachment orientations and borderline personality features: the mediating role of difficulties in interpersonal emotion regulation.","authors":"Irene Messina, Pietro Spataro, Giulia Gagliardini, Tatiana Rossi, Alessandro Grecucci","doi":"10.1186/s40479-025-00323-1","DOIUrl":"10.1186/s40479-025-00323-1","url":null,"abstract":"<p><p>BACKGROUND: Insecure attachment predicts borderline personality (BP), with emotion regulation widely recognized as a key mediator of this association. While interpersonal difficulties are central to BP, most studies have focused on intrapersonal emotion regulation, overlooking its interpersonal forms. Given the importance of understanding emotional and relational dysfunctions in BP, this study examined difficulties in Interpersonal Emotion Regulation (IER), investigating the role of maladaptive strategies—venting and excessive reassurance-seeking—as mediators in the relationship between attachment insecurity and BP. METHODS: A total of 420 adults completed self-report measures assessing BP features (PAI-BOR: affective instability, identity disturbances, negative relationships, and self-harm), attachment orientations (ECR-12: attachment anxiety and attachment avoidance), and IER difficulties (DIRE: venting and reassurance-seeking). Pearson’s correlations tested associations among variables, and a path analysis was conducted, using attachment anxiety and avoidance as exogenous variables, IER difficulties as mediators, and BP features as outcome variables. RESULTS: Attachment anxiety was positively associated with all BP features and greater difficulties in IER (venting and reassurance-seeking). IER mediated the relationship between attachment anxiety and BP features, with venting significantly mediating all BP dimensions. CONCLUSIONS: Findings highlight a self-perpetuating cycle of relational difficulties and emotional dysregulation in BP, with IER playing a crucial role. Excessive reliance on others for emotional regulation, likely stemming from mentalization impairments, may lead individuals with BP and anxious attachment to externalize distress, reinforcing negative moods and straining relationships. Psychological interventions should focus on breaking this cycle by enhancing emotion regulation abilities, fostering autonomy, and reducing maladaptive dependence on others for emotional relief. </p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"13 1","pages":"4"},"PeriodicalIF":3.2,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12874987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146127043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric properties of the Level of Personality Functioning Scale- Brief Form 2.0 (LPFS-BF 2.0) in women with attention-deficit/hyperactivity disorder.","authors":"Dara E Babinski, Daniel A Waschbusch","doi":"10.1186/s40479-025-00334-y","DOIUrl":"10.1186/s40479-025-00334-y","url":null,"abstract":"<p><strong>Background: </strong>Women with attention-deficit/hyperactivity disorder (ADHD) are also often diagnosed with personality disorders, yet research on reliable and valid assessments of personality pathology in this population has been limited.</p><p><strong>Methods: </strong>In this study, the psychometric properties of the Level of Personality Functioning Scale- Brief Form - 2.0 (LPFS-BF 2.0) were examined in a sample of 171 adult women with ADHD.</p><p><strong>Results: </strong>A two-factor structure was identified, with one factor, LPF-self, comprised of six items, reflecting impairment in self functioning; the second factor, LPF-interpersonal, comprised of six items, reflecting impairment in interpersonal functioning. LPFS-BF 2.0 factors contributed unique variance to functional impairment beyond the effects of co-occurring depression, anxiety, and ADHD.</p><p><strong>Conclusions: </strong>These findings suggest the LPFS-BF 2.0 may be important to include in clinical care for women with ADHD, to identify those women with ADHD who may require adjunctive intervention for personality pathology.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":"1"},"PeriodicalIF":2.7,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12829034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145918865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A laboratory task to assess epistemic mistrust: behavioral evidence for mediation between childhood trauma and borderline personality features in young adults.","authors":"Elizabeth Li, Chloe Campbell, Linda C Mayes, Georgia McRedmond, Patrick Luyten","doi":"10.1186/s40479-025-00333-z","DOIUrl":"10.1186/s40479-025-00333-z","url":null,"abstract":"<p><strong>Background: </strong>Disruptions in epistemic trust have been recognised as key sequelae of trauma and as markers of vulnerability to borderline personality pathology. However, prior research has relied primarily on self-reports and lacks behavioural measures of epistemic stance. The present pre-registered studies introduce a novel behavioural task-the Balloon Analogue Risk Task for Epistemic Trust (BART-ET)-and examine its associations with borderline personality features, trauma history, and psychological distress.</p><p><strong>Methods: </strong>Two cross-sectional studies were conducted with a combined sample of 273 young adults aged 18-25 (Study 1: N = 120; Study 2: N = 153). Participants completed self-report measures of borderline personality features (PAI-BOR) and epistemic trust, mistrust, and credulity (ETMCQ). Study 2 additionally included the Childhood Trauma Questionnaire (CTQ) and the Brief Symptom Inventory (BSI-GSI). All participants completed the BART-ET in a laboratory setting, which operationalised epistemic mistrust as the degree of deviation from a confederate experimenter's advice during a risk-taking task. Analyses involved correlational tests and structural equation modelling (SEM) to evaluate hypothesised associations and mediation pathways.</p><p><strong>Results: </strong>As expected, across both studies, higher levels of borderline personality traits were associated with greater epistemic mistrust-both behaviourally (on the BART-ET) and via self-report (ETMCQ)-and with greater epistemic credulity, but not with epistemic trust, as measured with the ETMCQ. Behavioural and self-report measures of mistrust were significantly correlated, suggesting convergent validity of the BART-ET as an index of epistemic mistrust. In Study 2, childhood trauma exposure was associated with borderline features and with epistemic mistrust assessed behaviourally and via self-report. Preregistered mediation models controlling for general distress (BSI-GSI) suggested that the association between childhood trauma and epistemic mistrust was not unique to BPD features.</p><p><strong>Conclusions: </strong>These findings suggest that epistemic mistrust-rather than a simple absence of trust-is a social-cognitive correlate of borderline personality vulnerability and trauma exposure in young adults. The results also indicate that the BART-ET may be a useful behavioural tool for studying epistemic mistrust in clinical contexts, though further validation is needed.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":"2"},"PeriodicalIF":2.7,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12853794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145844429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotion dysregulation and parent emotion socialization in mothers with and without borderline pathology.","authors":"Ashley Lubben, Tess Gecha, Kiana Cano, Carla Sharp","doi":"10.1186/s40479-025-00330-2","DOIUrl":"10.1186/s40479-025-00330-2","url":null,"abstract":"<p><strong>Background: </strong>Mothers with borderline personality disorder face unique challenges in parenting, as borderline symptoms have been shown to negatively affect parent-child relationships. These challenges can lead to non-supportive reactions to children's negative emotions, a form of parent emotion socialization (PES) that has been linked to negative outcomes in children. Given the inherent emotional arousal evoked by parenting, emotion dysregulation likely influences the type of PES parents utilize. However, few studies have specifically examined how emotion dysregulation affects PES in mothers with borderline pathology. Against this background, this study aims to (1) investigate the link between maternal emotion dysregulation and PES strategies and (2) assess if emotion dysregulation moderates the relationship between presence of significant borderline pathology and PES.</p><p><strong>Methods: </strong>The study sample was comprised of 148 mothers (Mage = 34.92). Of these mothers, 53 had significant borderline features-that is, they either met full diagnostic criteria or exhibited marked subthreshold symptoms. Emotion regulation was evaluated using the Difficulties in Emotion Regulation Scale - Short Form, and PES was assessed using the Coping with Children's Negative Emotion Scale. Significant borderline features were determined using the Personality Assessment Inventory Borderline Scale. As a part of aim 1, bivariate correlations were conducted to examine relationships between emotion dysregulation and two PES strategies: supportive and non-supportive. The moderating role of emotion dysregulation on the relationships between borderline features and supportive and non-supportive PES was assessed using two moderation models.</p><p><strong>Results: </strong>Results from the first aim revealed a small, negative correlation between emotion dysregulation and supportive PES and a medium, positive correlation between emotion dysregulation and non-supportive PES. Emotion dysregulation was found to be a significant moderator of the relationship between borderline pathology and non-supportive PES.</p><p><strong>Conclusions: </strong>The current study significantly contributes to the literature by further elucidating the relationship between maternal borderline pathology and PES and its underlying mechanisms.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"12 1","pages":"53"},"PeriodicalIF":3.2,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12729240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145829009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping caregivers' distress: a network analysis of burden, meaning in life, and mental health in families facing suicidal behavior.","authors":"Sandra Pérez-Rodríguez, Ginnette Muñoz Rocha, Joaquín García-Alandete, Verónica Guillén Botella, Jose H Marco","doi":"10.1186/s40479-025-00327-x","DOIUrl":"10.1186/s40479-025-00327-x","url":null,"abstract":"<p><strong>Background: </strong>Suicide profoundly impacts not only individuals but also their relatives, who often experience high levels of burden, distress, and isolation. Yet the interplay between risk and protective factors in this population remains understudied. This study explored the network structure of caregivers' emotional states, focusing on meaning in life, perceived burden, family empowerment, emotion dysregulation, anxiety, stress, depressive symptoms, and quality of life.</p><p><strong>Methods: </strong>A cross-sectional study was conducted with 185 Spanish relatives (139 women, 75.1%, and 46 men, 24.9%) age-ranged between 18 and 73 years old (M = 50.26, SD = 10.23) of individuals with suicide attempts or suicidal behavior disorder in the past two years. Networks were estimated with EBICglasso after redundant node analysis.</p><p><strong>Results: </strong>The network included 11 nodes and 30 edges. Depressive symptoms emerged as the most central node, followed by stress and anxiety, indicating that emotional distress is a central component of caregivers' functioning. Emotion dysregulation bridged distress with subjective burden. In contrast, meaning in life (especially its experiential dimension of Meaning) and quality of life appeared as protective but peripheral. Family empowerment also occupied a peripheral role, while objective and subjective burden were closely interconnected but less structurally influential.</p><p><strong>Conclusion: </strong>Findings highlight the central position of depressive symptoms within caregivers' emotional networks, suggesting that future research should further explore how distress and protective resources such as meaning in life and quality of life interact in shaping caregivers' well-being.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"12 1","pages":"54"},"PeriodicalIF":2.7,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12729015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145829040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A pilot randomized controlled study of a brief mentalizing enhancement intervention for borderline personality disorder.","authors":"Yogev Kivity, Nati Pasternak, Rotem Moshe-Cohen, Shir Ada Basson, Leeav Sheena-Peer, Noa Steinberg, Tom Livni","doi":"10.1186/s40479-025-00331-1","DOIUrl":"10.1186/s40479-025-00331-1","url":null,"abstract":"<p><strong>Background: </strong>Impairments in mentalizing, the capacity for understanding mental states, are central to borderline personality disorder (BPD). This study examined a brief mentalizing intervention aiming to enhance the capacity and motivation for mentalizing in BPD.</p><p><strong>Methods: </strong>Forty-eight adults with BPD (Sex: 81% female; Gender: 75% female) were randomized to a brief, single-session mentalizing or a control intervention. The mentalizing intervention involved prompts and practice in considering mental states underlying behaviors in interpersonal situations, while the control group involved an emotional sharing intervention. An observer-rated measure of mentalizing ability and a self-report measure of motivation for mentalizing were administered before and after the intervention. Self-report measures of subjective distress and the acceptability of the intervention were collected following the intervention.</p><p><strong>Results: </strong>A significant improvement in mentalizing abilities was observed following mentalizing-enhancement (d = 0.69, p = .002), but not emotional sharing (d = -0.07, p = .64). Participants in the mentalizing-enhancement group reported significantly lower post-intervention distress than the emotional sharing group (d = 0.64, p = .03). Unexpectedly, the motivation for mentalizing decreased in both groups (mentalizing-enhancement/emotional sharing: d = -1.62/-1.16, respectively, ps < 0.001).</p><p><strong>Discussion: </strong>Brief and focused mentalizing interventions may enhance mentalizing and reduce distress in BPD and could be utilized for tailoring interventions for specific BPD deficits.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"12 1","pages":"52"},"PeriodicalIF":2.7,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12713231/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145783489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Mediational Intervention for Sensitizing Caregivers: an evaluation of feasibility and acceptability among mothers with borderline personality disorder.","authors":"Kiana Cano, Nabeeha Asim, Madeleine Allman, Carla Sharp","doi":"10.1186/s40479-025-00317-z","DOIUrl":"10.1186/s40479-025-00317-z","url":null,"abstract":"<p><strong>Background: </strong>Extant data suggest that children of mothers with borderline personality disorder (BPD) are at risk for a variety of poor psychosocial outcomes, including psychopathology. One avenue for interrupting intergenerational transmission of psychopathology is through scaffolding parenting. The Mediational Intervention for Sensitizing Caregivers (MISC) has been used with other high-risk groups and holds promise for this population. The objective of the current study was to evaluate the feasibility and acceptability of MISC for mothers with BPD, and to identify key modifications for future adaptation of MISC for this population.</p><p><strong>Methods: </strong>This objective was accomplished via three aims following a best-practice adaptation model for evidence-based psychosocial interventions. Aim 1 consisted of quantitative assessment (phase 1) of need for parenting support with n = 88 mothers with BPD and n = 195 without, and qualitative assessment (phase 2) of the lived experience of parenting among 15 mothers with BPD. Aim 2 consisted of integration of mixed methods results from Aim 1, and the decision to proceed with adaptation of MISC for mothers with BPD. Aim 3 consisted of focus groups and theatre testing of MISC, with n = 14 mothers with BPD.</p><p><strong>Results: </strong>Aim 1 findings showed significant group differences on quantitative measures between mothers with and without BPD. Qualitative themes provided information about perceived need and desire for parenting support from the patient perspective. Aim 2 integration provided preliminary support for the feasibility and utility of MISC for mothers with BPD. Results of Aim 3 focus groups identified qualitative evidence in support of the acceptability of MISC for mothers with BPD. Additionally, participant feedback identified feasible and actionable modifications to MISC that can be implemented in future work with this population.</p><p><strong>Conclusions: </strong>The current study suggests that MISC is a potentially feasible and acceptable alternative for mothers with BPD who are interested in receiving professional parenting support services.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"12 1","pages":"51"},"PeriodicalIF":2.7,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12709825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145769462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of borderline personality features and level of personality functioning in explaining mentalizing capacity.","authors":"Charlotte S Zell, Kennedy M Balzen, Joseph Boudreaux, Francesca Penner, Carla Sharp","doi":"10.1186/s40479-025-00329-9","DOIUrl":"10.1186/s40479-025-00329-9","url":null,"abstract":"<p><strong>Background: </strong>Numerous studies have demonstrated that the Alternative Model for Personality Disorders (AMPD) outperforms traditional categorical nosology (i.e., Section II) in predicting an array of salient clinical outcomes. However, despite the centrality of social-cognitive impairments in personality disorder, few studies have examined the superiority of the AMPD over Section II in predicting social-cognitive deficits. The current study addresses this gap by evaluating the incremental validity of AMPD-defined level of personality functioning (LPF) versus borderline personality features in predicting mentalizing - a social-cognitive construct proposed to underlie the development of personality disorder.</p><p><strong>Method: </strong>Participants included 267 university students (M_age = 20.49, SD = 1.74) who completed self-report measures of LPF, borderline personality features, and two measures of mentalizing: the Reflective Functioning Questionnaire (RFQ) and the Mentalization Scale (MentS).</p><p><strong>Results: </strong>Hierarchical regressions revealed that LPF explained additional variance in the RFQ beyond borderline features and internalizing psychopathology. Although borderline features also incremented LPF in predicting the RFQ, additional variance explained was less than half that contributed by the LPF over borderline features. LPF also incremented the variance explained in the MentS total score and subscales over and above borderline features and internalizing symptoms, whereas borderline features did not increment LPF in predicting any of the MentS variables.</p><p><strong>Conclusions: </strong>These results strengthen the evidence base for the superiority of the AMPD over Section II and suggest that mentalizing deficits are better captured by LPF than borderline personality disorder symptoms. Findings support the extension of mentalization-based treatment to AMPD-defined personality disorder, which should be explored in future research.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":" ","pages":"3"},"PeriodicalIF":2.7,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12874996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145716553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subgroups of emotion dysregulation in adults: a latent profile analysis in a clinically heterogeneous population.","authors":"Martin Blay, Amaury Durpoix, Mario Speranza, Roland Hasler, Rosetta Nicastro, Eleonore Pham, Eva Rüfenacht, Luisa Weiner, Sébastien Weibel, Martin Debbane, Nader Perroud","doi":"10.1186/s40479-025-00319-x","DOIUrl":"10.1186/s40479-025-00319-x","url":null,"abstract":"<p><strong>Background: </strong>Even if it was first described in borderline personality disorder, emotion dysregulation (ED) is increasingly recognized as a transdiagnostic and dimensional construct, best understood along a continuum of severity rather than as a discrete category. Prior cluster-analytic studies have consistently explored heterogeneity within this continuum by identifying patient subgroups, but most were conducted in populations defined by specific diagnostic categories, limiting their generalizability. To better capture ED's core components, studies conducted in clinically heterogeneous adult populations are needed.</p><p><strong>Methods: </strong>In this context, we conducted a latent profile analysis on 349 adults referred for ED-related difficulties at a specialized outpatient clinic. Profiles were derived from the six subscales of the Difficulties in Emotion Regulation Scale. Patients were assessed on sociodemographic variables, emotion regulation difficulties and strategies, mentalizing abilities, comorbid psychopathology, and well-being.</p><p><strong>Results: </strong>A two-class solution was retained. Subgroups did not align with any specific diagnostic category but rather emerged along a severity continuum. Cluster 1 (n = 267) was characterized by more severe ED in every domain, higher use of non-adaptive regulation strategies, lower self-mentalizing abilities, greater comorbid psychopathology, and lower well-being. Cluster 2 (n = 82) displayed comparatively preserved emotion regulation abilities and strategies, higher self-mentalizing, fewer comorbidities, and greater well-being.</p><p><strong>Conclusions: </strong>Our findings provide further evidence for the existence and characterization of subgroups in patients with ED, reflecting gradations along a severity continuum. While exploratory, they also suggest that core mechanisms targeted by DBT and MBT (i.e., maladaptive emotion regulation strategies and self-mentalizing abilities) may be relevant therapeutic targets across a broader transdiagnostic spectrum.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"12 1","pages":"50"},"PeriodicalIF":2.7,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12679781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145679056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}