Tanchun Yu MS , Yixuan Jiang PhD , Renjie Chen PhD , Peng Yin PhD , Huihuan Luo PhD , Prof Maigeng Zhou PhD , Prof Haidong Kan PhD
{"title":"National and provincial burden of disease attributable to fine particulate matter air pollution in China, 1990–2021: an analysis of data from the Global Burden of Disease Study 2021","authors":"Tanchun Yu MS , Yixuan Jiang PhD , Renjie Chen PhD , Peng Yin PhD , Huihuan Luo PhD , Prof Maigeng Zhou PhD , Prof Haidong Kan PhD","doi":"10.1016/S2542-5196(25)00024-5","DOIUrl":"10.1016/S2542-5196(25)00024-5","url":null,"abstract":"<div><h3>Background</h3><div>Fine particulate matter (PM<sub>2·5</sub>) is the leading environmental risk factor for mortality and disability worldwide. We aimed to evaluate the temporal trend in, and spatial distribution of, the disease burden attributable to PM<sub>2·5</sub> in China from 1990 to 2021.</div></div><div><h3>Methods</h3><div>Based on the methodology framework and general analytical strategies applied in the Global Burden of Diseases, Injuries, and Risk Factors Study 2021, we calculated the numbers, age-standardised rates, and percentage of deaths and disability-adjusted life-years (DALYs) attributable to PM<sub>2·5</sub> air pollution from 1990 to 2021 at the national and provincial level in China, by disease, sex, and age groups. Exposure to PM<sub>2·5</sub>, including ambient PM<sub>2·5</sub> pollution and household PM<sub>2·5</sub> pollution from solid fuels, was evaluated across 33 provincial administrative units in China.</div></div><div><h3>Findings</h3><div>In 2021, 2·3 million (95% uncertainty interval [UI] 1·8–2·9) deaths and 46·7 million (36·6–59·7) DALYs could be attributable to PM<sub>2·5</sub> pollution in China, accounting for 19·4% (16·0–23·6) of total deaths and 11·6% (9·4–14·1) of total DALYs. Of these, 1·9 million (95% UI 1·3–2·3) deaths and 37·8 million (26·3–46·5) DALYs resulted from ambient exposure, while 0·4 million (0·1–1·3) deaths and 8·9 million (1·5–27·8) DALYs were due to household exposure from solid fuel use. Stroke, ischaemic heart disease, and chronic obstructive pulmonary disease were the leading three causes. Two peaks in the burden were observed: in children aged younger than 5 years, and in people aged 70 years and older. The percentage of deaths and DALYs due to ambient PM<sub>2·5</sub> was higher in men, while that due to household PM<sub>2·5</sub> was higher in women. Geographically, the disease burden from ambient PM<sub>2·5</sub> was higher in north and northwest China, while that from household PM<sub>2·5</sub> was higher in southwest China. From 1990 to 2021, age-standardised death rates attributable to total PM<sub>2·5</sub> decreased by 66·0% (95% UI 57·7–73·1) and those attributable to household PM<sub>2·5</sub> decreased by 92·2% (76·6–98·7), with larger reductions observed in east and south China. By contrast, the disease burden related to ambient PM<sub>2·5</sub> continued to increase and only began to decline in the past decade.</div></div><div><h3>Interpretation</h3><div>Despite the decline in the disease burden attributable to total PM<sub>2·5</sub> in China during 1990–2021, ambient PM<sub>2·5</sub> remains a major contributor to mortality and disability. This study highlights considerable spatial heterogeneity across different provinces and provides valuable insights for developing geographically tailored strategies for PM<sub>2·5</sub> control and public health promotion in China. Stricter control of ambient air pollution is needed in northern and northwestern regions, while p","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":"9 3","pages":"Pages e174-e185"},"PeriodicalIF":24.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Public engagement with health and climate change around the world: a Google Trends analysis","authors":"Prof Niheer Dasandi PhD , Prof Slava Jankin PhD , Dafni Kalatzi Pantera PhD , Marina Romanello PhD","doi":"10.1016/S2542-5196(25)00029-4","DOIUrl":"10.1016/S2542-5196(25)00029-4","url":null,"abstract":"<div><div>Despite growing recognition of the importance of people engaging with the health dimensions of climate change, we know surprisingly little about the levels of public engagement around the world. We address this knowledge gap by examining Google Trends data, using people's online information-seeking behaviour to shed light on global engagement with health and climate change between 2014 and 2023. We observe that over the past decade—and particularly since 2020—there has been growing public engagement via Google searches with health and climate change around the world. The increasing engagement with the intersection of health and climate change is largely distinct from engagement with either climate change or health separately. We observe that such engagement is highest in low-income and middle-income countries. There is also greater engagement with health and climate change than with other issues that intersect climate change—eg, the economy and security—highlighting the public salience of health framings of climate change.</div></div>","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":"9 3","pages":"Pages e236-e244"},"PeriodicalIF":24.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dengkai Chi PhD , Gabriele Manoli PhD , Brenda Lin PhD , Raf Aerts PhD , Prof Jun Yang PhD , Amy Hahs PhD , Daniel Richards PhD , Naika Meili PhD , Yue Zhu PhD , Yeshan Qiu MSc , Jing Wang MSc , Prof Paolo Burlando PhD , Prof Simone Fatichi PhD , Prof Puay Yok Tan PhD
{"title":"Residential tree canopy configuration and mortality in 6 million Swiss adults: a longitudinal study","authors":"Dengkai Chi PhD , Gabriele Manoli PhD , Brenda Lin PhD , Raf Aerts PhD , Prof Jun Yang PhD , Amy Hahs PhD , Daniel Richards PhD , Naika Meili PhD , Yue Zhu PhD , Yeshan Qiu MSc , Jing Wang MSc , Prof Paolo Burlando PhD , Prof Simone Fatichi PhD , Prof Puay Yok Tan PhD","doi":"10.1016/S2542-5196(25)00022-1","DOIUrl":"10.1016/S2542-5196(25)00022-1","url":null,"abstract":"<div><h3>Background</h3><div>Residential exposure to trees has been associated with reduced mortality risks. We hypothesise that in addition to tree canopy cover, tree canopy configuration also plays a role in exposure–mortality relationships. As there is limited evidence on this hypothesis, especially longitudinal evidence, we performed a nationwide study to investigate the residential tree canopy configuration–mortality associations in the Swiss population.</div></div><div><h3>Methods</h3><div>In this longitudinal study, the tree canopy cover and configuration metrics within 500 m of individuals’ residences were quantified using high-resolution tree canopy data (1 × 1 m) from 2010 to 2019. We developed single-exposure and multi-exposure time-varying Cox regression models to estimate the associations between the different exposure metrics and natural-cause and cause-specific mortality in Swiss adults (aged from 20 years to 90 years). Mortality and census data were taken from the Swiss National Cohort (SNC). We estimated the hazard ratios (HRs) and corresponding 95% CIs per IQR increase in the metrics adjusting for personal sociodemographic and contextual covariates. We also explored the effect modification by tree canopy cover, PM<sub>10</sub>, air temperature, urbanisation level, age, sex, and area-based local socioeconomic position.</div></div><div><h3>Findings</h3><div>Our analyses included 6 215 073 individuals from the SNC between 2010 and 2019. In the fully adjusted single-exposure models, we observed protective associations between natural-cause mortality risk and tree canopy cover (IQR 12·4%, HR 0·979 [95% CI 0·975–0·983]) and configuration metrics describing the aggregation (6·3%, 0·831 [0·823–0·840]), and connectedness (2·9%, 0·946 [0·938–0·953]); and detrimental associations with two metrics describing the fragmentation (211 patches per 100 ha, 1·073 [1·066–1·080]) and shape complexity (1·9, 1·094 [1·089–1·100]) of patches. The associations were generally preserved with other common causes of death. According to the multi-exposure models, the HR (95% CI) for the combination of one IQR decrease in aggregation and one IQR increase in fragmentation and shape complexity was 1·366 (1·343–1·390). Analyses on modification effects suggested a stronger association in people living in areas with a higher level of tree canopy cover, PM<sub>10</sub> concentration, air temperature, and urbanisation level.</div></div><div><h3>Interpretation</h3><div>Aggregated, connected, and less fragmented forested greenspaces might offer stronger health benefits than isolated, fragmented ones, but are difficult to implement in cities. Our study provided valuable insights into optimising forested greenspaces and highlighted future directions for the planning and management of urban forests towards healthy and green cities.</div></div><div><h3>Funding</h3><div>National Research Foundation, Prime Minister's Office, Singapore under its Campus for Research Excellence","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":"9 3","pages":"Pages e186-e195"},"PeriodicalIF":24.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Planetary Health Research Digest","authors":"Cahal McQuillan","doi":"10.1016/S2542-5196(25)00057-9","DOIUrl":"10.1016/S2542-5196(25)00057-9","url":null,"abstract":"","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":"9 3","pages":"Page e172"},"PeriodicalIF":24.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adrien Talbot MD , Hans Christian Holländer MBA , Prof Peter Bentzer MD
{"title":"Greenhouse gas impact from medical emissions of halogenated anaesthetic agents: a sales-based estimate","authors":"Adrien Talbot MD , Hans Christian Holländer MBA , Prof Peter Bentzer MD","doi":"10.1016/S2542-5196(25)00027-0","DOIUrl":"10.1016/S2542-5196(25)00027-0","url":null,"abstract":"<div><h3>Background</h3><div>Halogenated anaesthetic agents are potent greenhouse gases, but little is known about the trajectory of their use and their greenhouse gas impact on a global level. The primary aim of this study was to estimate the global greenhouse gas impact of halogenated anaesthetic agents over the preceding 10 years.</div></div><div><h3>Methods</h3><div>We obtained global medical sales data for sevoflurane, desflurane, isoflurane, halothane, and methoxyflurane from the IQVIA MIDAS database between 2014 and 2023. We calculated their annual greenhouse gas impact, expressed as carbon dioxide equivalents (CO<sub>2</sub>e), using global warming potential factors for a 100-year period. The effect of using only sevoflurane, the clinically relevant alternative with the lowest impact, was estimated by calculating the volume of sevoflurane that was needed to replace the other agents for a standard anaesthesia using a simulation software (Gas Man).</div></div><div><h3>Findings</h3><div>The 91 countries in the dataset represented 97·8%, 90·5%, and 66·2% of the population in high-income, upper-middle-income, and low-income or lower-middle-income countries, respectively, and covered 80·0% of the global population in 2023. The greenhouse gas impact of halogenated anaesthetic agents decreased by 27% from 2754 kilotons of CO<sub>2</sub>e (ktonCO<sub>2</sub>e) in 2014 to 2005 ktonCO<sub>2</sub>e in 2023. During the study period, the greenhouse gas impact from desflurane in high-income countries decreased by 52% from 2180 to 1053 ktonCO<sub>2</sub>e, increased in upper-middle-income countries by 151% from 125 to 313 ktonCO<sub>2</sub>e, and increased in low-income and lower-middle-income countries by 2281% from 2 to 42 ktonCO<sub>2</sub>e. By replacing desflurane, isoflurane, and halothane with sevoflurane, the global impact from halogenated anaesthetic agents in 2023 could theoretically have been decreased by 73%.</div></div><div><h3>Interpretation</h3><div>The global greenhouse gas impact from halogenated anaesthetic agents is falling due to lower use of desflurane in high-income countries. Efforts to reverse the increased use of desflurane in middle-income countries are needed. Replacing desflurane and isoflurane with sevoflurane constitutes an opportunity to markedly reduce the greenhouse gas impact from halogenated anaesthetic agents.</div></div><div><h3>Funding</h3><div>The Thelma Zoega Foundation, The Anna and Edwin Berger Foundation, Region Skåne, and a Swedish Government grant for clinical research within the Swedish National Health Service (ALF).</div></div>","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":"9 3","pages":"Pages e227-e235"},"PeriodicalIF":24.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The imperative for actions to protect and promote human health within Earth-system boundaries","authors":"Andy Haines , Jemilah Mahmood","doi":"10.1016/S2542-5196(25)00023-3","DOIUrl":"10.1016/S2542-5196(25)00023-3","url":null,"abstract":"","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":"9 2","pages":"Pages e80-e82"},"PeriodicalIF":24.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143445167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Léo Moutet PharmD , Paquito Bernard PhD , Prof Rosemary Green PhD , James Milner PhD , Prof Andy Haines FMedSci , Rémy Slama PhD , Prof Laura Temime PhD , Kévin Jean PhD
{"title":"The public health co-benefits of strategies consistent with net-zero emissions: a systematic review","authors":"Léo Moutet PharmD , Paquito Bernard PhD , Prof Rosemary Green PhD , James Milner PhD , Prof Andy Haines FMedSci , Rémy Slama PhD , Prof Laura Temime PhD , Kévin Jean PhD","doi":"10.1016/S2542-5196(24)00330-9","DOIUrl":"10.1016/S2542-5196(24)00330-9","url":null,"abstract":"<div><div>Moving towards net-zero emission societies is projected to provide human health co-benefits. However, the magnitude of these co-benefits is poorly documented and might be context specific. Synthesising the evidence on these co-benefits could enhance the engagement of decision makers and populations in climate mitigation actions. We performed database searches of PubMed, Web of Science, and Scopus for studies published between database inception and Jan 1, 2024, identifying 3976 papers. Of these, 58 quantitative studies met our inclusion criteria and were included in this systematic review. These 58 papers explored 125 net-zero emission scenarios and considered various pathways by which climate policies can affect human health. Pathways addressing air quality, physical activity, and dietary changes found substantial health co-benefits, with a median mortality reduction of 1·5%. National or sub-national studies showed that net-zero policies would yield substantial local air quality benefits, independently of the actions taken in neighbouring countries. However, these co-benefits varied with explored emission sector, decarbonisation levers, modelling approach, and location. Studies that included a cost–benefit analysis estimated that monetised benefits outweighed the costs of implementing climate policies. This systematic review highlights the need for a standardised framework to assess and compare health impacts of climate mitigation actions across sectors and confirms that achieving net-zero goals supports far-reaching public health policies.</div></div><div><h3>Translation</h3><div>For the French translation of the abstract see Supplementary Materials section.</div></div>","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":"9 2","pages":"Pages e145-e156"},"PeriodicalIF":24.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}