Lancet Planetary Health最新文献

{"title":"Commercial determinants of active travel: a crucial but overlooked barrier to health and sustainability.","authors":"Carmen Jochem, Karim Abu-Omar, Dorothea Baltruks, Adrian Bauman, Ding Ding, Sonja Kahlmeier, Lisa Paulsen, Lydia Reismann, Birgit Wallmann-Sperlich, Jens Bucksch","doi":"10.1016/j.lanplh.2025.101340","DOIUrl":"https://doi.org/10.1016/j.lanplh.2025.101340","url":null,"abstract":"","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":" ","pages":"101340"},"PeriodicalIF":21.6,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145293782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Planetary Health Research Digest.","authors":"Cahal McQuillan","doi":"10.1016/j.lanplh.2025.101343","DOIUrl":"https://doi.org/10.1016/j.lanplh.2025.101343","url":null,"abstract":"","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":" ","pages":"101343"},"PeriodicalIF":21.6,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal exposure to perfluoroalkyl substances predicts multimodal brain structural and functional outcomes in children aged 5 years: a birth cohort study.","authors":"Aaron Barron, Alex M Dickens, Jetro J Tuulari, Tuulia Hyötylainen, Susanna Kortesluoma, Harri Merisaari, Elmo P Pulli, Eero Silver, Venla Kumpulainen, Anni Copeland, Ekaterina Saukko, John D Lewis, Linnea Karlsson, Matej Orešič, Hasse Karlsson","doi":"10.1016/j.lanplh.2025.101309","DOIUrl":"https://doi.org/10.1016/j.lanplh.2025.101309","url":null,"abstract":"<p><strong>Background: </strong>Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are ubiquitous persistent organic pollutants associated with adverse health outcomes in humans. Although they are associated with autism spectrum disorder and behavioural outcomes, whether PFAS affect brain development is unclear. We aimed to characterise the relationship between maternal PFAS and brain structure and function in typically developing children.</p><p><strong>Methods: </strong>This study was set within the FinnBrain Birth Cohort Study, a prospective observational study that enrolled mothers from three clinics in Turku, Finland, during their first trimester of pregnancy. Maternal serum samples at gestational week 24 were analysed for PFAS by mass spectrometry and, at age 5 years, children were assessed through structural, diffusion-weighted, and functional MRI. Whole-brain voxel-level and vertex-level maps of grey matter volume, white matter fractional anisotropy and mean diffusivity, and cortical thickness and surface area were combined to compute ten independent components. Data were analysed by correlation network, elastic net regression, and multivariate linear regression with multiple testing correction.</p><p><strong>Findings: </strong>Pregnant mothers were enrolled into the birth cohort study between Dec 1, 2011, and April 30, 2015, and study visits at age 5 years took place between Oct 1, 2017, and March 31, 2020. This analysis involved 51 mother-child dyads for whom maternal PFAS concentrations and structural MRI data for the child were available. PFAS concentrations in maternal serum samples were mostly 0-1 ng/mL. Maternal perfluorononanoic acid (PFNA; R²=0·13, β=0·39 [95% CI 0·09-0·69], p_adj=0·024) and linear perfluorooctanoic acid (PFOA; 0·13, 0·36 [0·09-0·63], p_adj=0·022) linearly predicted a multimodal component dominated by corpus callosal integrity, whereas branched perfluorohexanesulphonic acid (PFHxS; R²=0·12, β=0·31, p_adj=0·036) and branched PFOA (R²=0·14, β=0·36, p_adj=0·016) predicted a component comprising mainly occipital cortex volume and surface area. Branched perfluorooctanesulphonic acid predicted hypothalamic microstructure (R²=0·10, β=0·29, p=0·026). PFNA, linear PFOA, and branched PFOA are associated with increased functional connectivity in the right precentral gyrus, whereas branched PFHxS predicts decreased connectivity in the intracalcerine cortices. Associations were not influenced by sex assigned at birth, but were related to PFAS chemical structure.</p><p><strong>Interpretation: </strong>We show an association between prenatal PFAS exposure and brain developmental outcomes in children. These findings are pertinent given the ubiquitous circulation of PFAS in humans and the extreme environmental persistence of these substances.</p><p><strong>Funding: </strong>The Horizon Europe programme of the EU.</p>","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":" ","pages":"101309"},"PeriodicalIF":21.6,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping landscape fire-sourced air pollution-related mortality across 2288 local communities in Australia: a nationwide health impact assessment.","authors":"Zhihu Xu, Rongbin Xu, Wenzhong Huang, Zhengyu Yang, Yiwen Zhang, Zhaoyuan Li, Yunfei Xing, Wenhua Yu, Susan Maury, Yuming Guo, Shanshan Li","doi":"10.1016/j.lanplh.2025.101305","DOIUrl":"https://doi.org/10.1016/j.lanplh.2025.101305","url":null,"abstract":"<p><strong>Background: </strong>Landscape fire-sourced (LFS) air pollution has been linked to increased mortality, which is especially concerning in fire-prone regions such as Australia. However, there is little evidence on how this increased mortality and associated economic burden might vary by region in Australia or on the factors driving such regional differences. To address this gap, we aimed to estimate the community-level mortality burden and economic loss from LFS air pollution and examine the socioeconomic factors contributing to regional health disparities across 2288 communities in Australia.</p><p><strong>Methods: </strong>We obtained individual death records and community characteristics from the Australian Bureau of Statistics, together with community-level population-weighted average daily and annual estimates of LFS fine particulate matter (PM_2.5) and surface ozone (O₃) during 2009-19 from a validated dataset. We used two-stage time series analyses to derive relative risks for the short-term mortality risks of LFS PM_2·5 and O₃. By integrating recent evidence on long-term mortality impacts of all-source PM_2·5 and O₃, we calculated the total LFS air pollution-related mortality burden (including both short-term and long-term burdens) and economic loss for each of the 2288 communities (statistical area level 2) in Australia. Mortality burden was expressed as attributable deaths, attributable fractions, and attributable mortality rates. Economic loss was quantified with the value of statistical life approach on the basis of willingness-to-pay estimates.</p><p><strong>Findings: </strong>Between 2016 and 2019, LFS air pollution was responsible for 22 809 (95% CI 19 276-26 435) all-cause deaths in Australia, valued at AU$138·41 billion (95% CI 116·97-160·41). Communities in the Northern Territory had the highest LFS air pollution-related excess mortality rate, at 33·97 (95% CI 29·12-39·20) per 100 000 residents per year, followed by communities in New South Wales and Queensland, whereas Southern Australia had the lowest burden, at 12·25 (10·64-14·04) deaths per 100 000 residents per year. Notably, mortality burdens were greater in communities with higher proportions of Indigenous Australian residents or residents of lower socioeconomic status and in communities situated in rural locations.</p><p><strong>Interpretation: </strong>This study provides a comprehensive analysis of the mortality burden and economic loss associated with LFS air pollution, highlighting a clear socioeconomic inequality in health burdens across Australian communities. The results-presented as community-level mortality burden maps-could inform the development of targeted public health interventions and climate policies at both local and national levels.</p><p><strong>Funding: </strong>The Australian Research Council, Australian National Health and Medical Research Council, and VicHealth.</p>","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":" ","pages":"101305"},"PeriodicalIF":21.6,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardising the measurement of child health indicators within global climate adaptation.","authors":"Ilan Cerna-Turoff, Sayaka Horiuchi, Marzia Lazzerini, Luis Huicho, Sk Masum Billah, Ralf Weigel, Maria Muñiz, Kathleen Strong","doi":"10.1016/j.lanplh.2025.101320","DOIUrl":"https://doi.org/10.1016/j.lanplh.2025.101320","url":null,"abstract":"","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":" ","pages":"101320"},"PeriodicalIF":21.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145228556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Planetary Health Research digest.","authors":"Cahal McQuillan","doi":"10.1016/j.lanplh.2025.101336","DOIUrl":"https://doi.org/10.1016/j.lanplh.2025.101336","url":null,"abstract":"","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":" ","pages":"101336"},"PeriodicalIF":21.6,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145179348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ageing-related functional and cognitive impairments and cold mortality risk: a longitudinal cohort study in China.","authors":"Di Xi, Linxin Liu, Jialu Song, Min Zhang, Yi Zeng, John S Ji","doi":"10.1016/j.lanplh.2025.101301","DOIUrl":"https://doi.org/10.1016/j.lanplh.2025.101301","url":null,"abstract":"<p><strong>Background: </strong>Cold-related mortality is the leading contributor to the disease burden from non-optimal temperatures in China. In this study, we aimed to explore ageing-related risk factors, advance our understanding of temperature-related mortality, and enhance the accuracy of relative risk measures.</p><p><strong>Methods: </strong>We assessed daily cold spell exposure individually for 13 527 participants with a median age of 89 years (IQR 78-96) and 4659 winter mortalities during follow-up from 2008 to 2018 in the Chinese Longitudinal Healthy Longevity Survey. We used a time-varying Cox proportional hazards model to capture daily variations in cold spell exposure, adjusting for individual-level demographics, multidimensional measures of functional status, and socioeconomic factors. We also examined effect modification by demographics, functional status measures, comorbidities, and socioeconomic factors. The primary outcome is all-cause mortality recorded from 2008 to 2018.</p><p><strong>Findings: </strong>Cold spell days were associated with a near-doubling of mortality risk (hazard ratio [HR] 1·87-2·08). Individuals with impaired physical functional status, particularly those dependent on activities of daily living (eg, bathing, dressing, eating, toileting, cooking, carrying weights of 5 kg, doing laundry, and taking public transportation), exhibited significantly higher vulnerability (HR 2·23-3·74). Cognitive impairments, notably in attention and calculation, orientation, and short-term memory, also increased risk (HR 2·23-2·41). Women faced greater mortality risk than men (HR 2·17-2·27 vs 1·50-1·89). Self-reported chronic disease comorbidities did not significantly modify these associations.</p><p><strong>Interpretation: </strong>Beyond age as a general risk factor, to reduce cold-related mortality in China, interventions should prioritise older adults with impaired activities of daily living (eg, bathing or dressing) and cognitive deficits (eg, attention and calculation or short-term memory), particularly women. Community-based programmes, such as subsidised heating and real-time cold alert systems, combined with targeted caregiver support for functionally dependent individuals, could mitigate risks.</p><p><strong>Funding: </strong>Data collection was jointly supported by the National Key R&D Program of China (number 2018YFC2000400), the National Natural Science Foundation of China (number 72061137004), the US National Institute of Aging, National Institutes of Health (number P01AG031719), and Beijing TaiKang YiCai Public Welfare Foundation. The study was supported by the National Natural Science Foundation of China (number 82422064, 82250610230), the Natural Science Foundation of Beijing (number IS23105), and the Tsinghua University Vanke School of Public Health Research Fund (number 2021PY001).</p>","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":" ","pages":"101301"},"PeriodicalIF":21.6,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145151340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical activity in context: the systems and inequalities of metabolic harm.","authors":"Alex Broom, Imogen Harper, Jakelin Troy, Louise Baur, Emmanuel Stamatakis","doi":"10.1016/j.lanplh.2025.101323","DOIUrl":"https://doi.org/10.1016/j.lanplh.2025.101323","url":null,"abstract":"<p><p>Physical inactivity and sedentary lifestyles are now accepted as major contributors to metabolic harm and disorder in the 21st century. These harms are frequently framed as a result of individual choices, with solutions leaning into personal responsibility. There are, however, crucial structural influences on individuals' capacity to engage with so-called lifestyle advice. In particular, the way in which structural environments influence labour, lives, and communities can present several barriers to exercise and physical activity. These pressures, and their consequences, have particular and compounding effects on those who are economically and socially marginalised. When scientific and clinical literature overlooks these structural determinants of lifestyle, the effectiveness of interventions are undermined, or even worse, intervention failure reinforces judgement and isolation, which cements metabolically harmful behaviours. In this Viewpoint, we call for renewed focus on how social structures influence physical activity to characterise the injustices underpinning current metabolic health and harm.</p>","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":" ","pages":"101323"},"PeriodicalIF":21.6,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How far can neutrality go?","authors":"Oliver Razum, Nataliia Lepska, Maksym Lepskyi, Diego S Silva","doi":"10.1016/j.lanplh.2025.101322","DOIUrl":"https://doi.org/10.1016/j.lanplh.2025.101322","url":null,"abstract":"","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":" ","pages":"101322"},"PeriodicalIF":21.6,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145103054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toxic trade: shipbreaking in South Asia.","authors":"Udani Samarasekera","doi":"10.1016/j.lanplh.2025.101333","DOIUrl":"https://doi.org/10.1016/j.lanplh.2025.101333","url":null,"abstract":"","PeriodicalId":48548,"journal":{"name":"Lancet Planetary Health","volume":" ","pages":"101333"},"PeriodicalIF":21.6,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}