Epidemiology and Health最新文献

Effect of long-term blood pressure trajectory on the future development of chronic kidney disease: an analysis of data from the Korean National Insurance Health Checkup Study. 长期血压轨迹对慢性肾脏病未来发展的影响：韩国国民保险健康体检研究数据分析。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2024-11-19 DOI: 10.4178/epih.e2024090

Wonmook Hwang, Eu Jin Lee, Jae-Hyeong Park, Soon-Ki Ahn

{"title":"Effect of long-term blood pressure trajectory on the future development of chronic kidney disease: an analysis of data from the Korean National Insurance Health Checkup Study.","authors":"Wonmook Hwang, Eu Jin Lee, Jae-Hyeong Park, Soon-Ki Ahn","doi":"10.4178/epih.e2024090","DOIUrl":"https://doi.org/10.4178/epih.e2024090","url":null,"abstract":"Objectives: Chronic kidney disease (CKD) is a prevalent health issue that causes the irreversible loss of functioning nephrons, end-stage renal disease, cardiovascular disease, and premature mortality. Hypertension is the leading cause of CKD. However, the effect of long-term blood pressure (BP) changes on the development of CKD is still unknown. Therefore, the current study investigated the association between BP trajectory and the future development of CKD.Methods: In this study, 246,874 individuals aged ≥40 years who underwent health examinations during the screening period (2002-2009) were evaluated. The systolic BP (SBP) trajectory was determined using latent-class mixture modeling. New-onset CKD was identified during the follow-up period (2010-2019). The association between SBP trajectories and new-onset CKD was assessed.Results: In total, 111,900 adults (53,420 women, 51.9  6.4 years old) presented with 2 SBP trajectory classes: class 1 (n = 66,935) and class 2 (n = 44,965). During the follow-up period, patients with SBP trajectory class 2 had an approximately 2.1-fold increased risk of developing CKD (unadjusted hazard ratio [HR], 2.114; 95% confidence interval [CI], 1.989-2.246, p<0.001). In the multivariate analysis adjusted for other significant variables, SBP trajectory class 2 was significantly associated with CKD in men (HR, 1.093; 95% CI, 1.005-1.189; p=0.037), but not in women (HR, 1.059; 95% CI, 0.947-1.184; p=0.321).Conclusion: An elevated longitudinal BP was associated with a higher incidence of CKD in male participants aged ≥40 years. Nevertheless, further studies are needed to validate the clinical significance of an elevated SBP trajectory on CKD development.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2024090"},"PeriodicalIF":2.2,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cohort study profile: a cohort of Korean atomic bomb survivors and their offspring. 队列研究概况：朝鲜原子弹爆炸幸存者及其后代队列。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2024-11-18 DOI: 10.4178/epih.e2024089

Hamin Lee, Jin-Wu Nam, Mi Kyung Kim, Inah Kim, Yu-Mi Kim, Boyoung Park

{"title":"Cohort study profile: a cohort of Korean atomic bomb survivors and their offspring.","authors":"Hamin Lee, Jin-Wu Nam, Mi Kyung Kim, Inah Kim, Yu-Mi Kim, Boyoung Park","doi":"10.4178/epih.e2024089","DOIUrl":"https://doi.org/10.4178/epih.e2024089","url":null,"abstract":"The Korean Atomic Bomb Survivor Cohort (K-ABC) study was designed to investigate the health impacts of atomic bomb exposure on Korean survivors and to explore whether these effects are passed down genetically to their descendants. This paper outlines the study's design, data collection methods, baseline sociodemographic characteristics, exposure status, and disease prevalence among the participants, based on survey responses and health examinations. From 2020 to 2024, a total of 2,544 individuals, comprising 1,109 atomic bomb survivors (G1), 1,193 children of G1 (G2), and 242 grandchildren of G1 (G3), consented to participate in the study. Of these, 1,828 participants (659 in G1, 927 in G2, and 242 in G3) completed the survey and underwent health examinations, representing a participation rate of 71.9%. Exposure information was gathered using a questionnaire and verified through records from the Korean Red Cross and a handbook issued by the Japanese government. Disease prevalence was determined based on participants' self-reported physician diagnoses. This study presents details about the K-ABC study and provides baseline data on the participants recruited. These data will be valuable for interpreting the results of future K-ABC studies.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2024089"},"PeriodicalIF":2.2,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Importance of younger age group and high inflammatory status in the association between periodontal disease and diabetes mellitus. 牙周病与糖尿病之间的关联中，年轻群体和高炎症状态的重要性。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2024-11-15 DOI: 10.4178/epih.e2024088

Hyunmin Lee, Myung-Hee Shin

{"title":"Importance of younger age group and high inflammatory status in the association between periodontal disease and diabetes mellitus.","authors":"Hyunmin Lee, Myung-Hee Shin","doi":"10.4178/epih.e2024088","DOIUrl":"https://doi.org/10.4178/epih.e2024088","url":null,"abstract":"Objectives: Although previous studies have demonstrated an association between periodontal disease (PD) and diabetes mellitus (DM), the influence of age and the mediating role of inflammation have seldom been explored. This study investigated this association while considering the modifying effects of age and inflammatory status.Methods: This study included 29,491 participants from the 2012-2018 Korea National Health and Nutrition Examination Survey. The community periodontal index (CPI) was assessed by trained dentists using the World Health Organization CPI probe. PD was defined as a CPI score of 3 or 4. Pre-existing and incident DM were identified based on serum glucose levels, a history of DM diagnosis, medication use, and insulin injections. Serum high-sensitivity C-reactive protein (hs-CRP) levels were utilized as an indicator of chronic inflammation.Results: PD and DM exhibited a significant association, which was more pronounced with incident DM than with pre-existing DM, particularly in individuals younger than 65 years. Among those aged 20-44 years, the odds ratio of incident DM for CPI=4 versus CPI=0 was 2.61 (95% confidence interval, 1.16-6.09). High hs-CRP levels (≥3 mg/L) were also associated with DM, especially in individuals with PD. This association was stronger with incident DM than with pre-existing DM. A notable joint effect was observed in younger individuals and those with PD.Conclusion: The association between PD and DM was more pronounced in younger age groups and those with higher levels of inflammation. Therefore, early interventions for PD in younger patients may be crucial for preventing DM.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2024088"},"PeriodicalIF":2.2,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characteristics of imported and domestic malaria cases in Gyeonggi Province, Republic of Korea. 大韩民国京畿道进口和国产疟疾病例的特征。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2024-11-08 DOI: 10.4178/epih.e2024087

Sunghee Hong, Jihye Kim, Soo-Nam Jo, Jong-Hun Kim, Boyoung Park, Bo Youl Choi

{"title":"Characteristics of imported and domestic malaria cases in Gyeonggi Province, Republic of Korea.","authors":"Sunghee Hong, Jihye Kim, Soo-Nam Jo, Jong-Hun Kim, Boyoung Park, Bo Youl Choi","doi":"10.4178/epih.e2024087","DOIUrl":"10.4178/epih.e2024087","url":null,"abstract":"Objectives: This study explored 11 years of malaria data from mandatory reporting in Gyeonggi Province, Korea, to provide information for prevention strategies by linkage to nationwide health claims data.Methods: Reported malaria cases in Gyeonggi Province from 2011 to 2021 were linked to medical usage data from the National Health Insurance Database. Data about hospitalization, antibiotic prescription and duration, malarial species, and sociodemographic information of the cases were included.Results: Between 2011 and 2021, a total of 3,011 malaria cases were reported, consisting of 2,828 domestic (93.9%) and 183 imported (6.1%) cases. Over 80% of the cases involved males, with the majority of patients being in their 20s. Both domestic and imported cases peaked between June and August over the years. Imported cases had a higher hospitalization rate (66.9%) compared to domestically-acquired cases (54.9%). There was a significant variation in treatment rates, with 80.7% of imported cases and 74.6% of domestic cases receiving treatment. For domestic cases, chloroquine combined with primaquine was the most commonly prescribed treatment (77.0%), while atovaquone-proguanil was frequently used for imported cases (25.9%). Plasmodium vivax was the predominant species in domestic cases (94.9%), whereas Plasmodium malariae was more common in imported cases (62.3%). The overall number of reported malaria cases declined following a sharp decrease in imported cases in 2020 and 2021.Conclusion: Despite a decreasing trend in malaria cases reported in Gyeonggi Province, imported cases exhibited higher hospitalization rates and different antibiotic prescription and treatment patterns, reflecting the presence of a different malarial species.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2024087"},"PeriodicalIF":2.2,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An outbreak of Clostridium perfringens infection on a training ship anchored in Busan, Korea. 停泊在韩国釜山的一艘训练舰上爆发了产气荚膜梭菌感染。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2024-11-07 DOI: 10.4178/epih.e2024086

Seonmi Kim, Hyunjin Son

{"title":"An outbreak of Clostridium perfringens infection on a training ship anchored in Busan, Korea.","authors":"Seonmi Kim, Hyunjin Son","doi":"10.4178/epih.e2024086","DOIUrl":"10.4178/epih.e2024086","url":null,"abstract":"Objectives: In September 2023, an outbreak of food-borne disease occurred among students on a training ship docked in Busan. This was an epidemiological investigation with the aim of improving infection prevention activities and group meal service practices on board ships.Methods: In this study, a case was defined as an individual who experienced diarrhea more than twice a day during their training period aboard the training ship. A total of 171 exposed individuals including 6 food handlers was well-defined; therefore, a retrospective cohort study was conducted. We administered a questionnaire and conducted laboratory tests including 38 rectal swab samples. Relative risk (95% confidence interval) for each food item was calculated.Results: Of the 165 students and school staff members, 41 met the case definition, resulting in an attack rate of 24.8%; all cases were students. The shape of the epidemic curve was unimodal, with the peak from 0:00 to 06:00 on September 7, 2023. Clostridium perfringens was detected in 9 cases, and no other pathogens were found. Significant relative risk was shown in 11 different food items.Conclusion: Clostridium perfringens was the causative pathogen of this outbreak on the training ship. Due to the lack of preserved food samples, the exact source of infection could not be confirmed. Ships are not classified as collective dining facilities, leaving them in a management blind spot. Therefore, specialized guidelines, voluntary inspections by the operating entities, and continuous education for managers and staff are necessary.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2024086"},"PeriodicalIF":2.2,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The prevention and response to infectious diseases in long-term care facilities in Korea: a nationwide survey. 韩国长期护理机构的传染病预防和应对措施：一项全国性调查。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2024-10-17 DOI: 10.4178/epih.e2024084

Sun Hee Na, Joong Sik Eom, Sun Bean Kim, Hyung Jin Yoon, So Yeon Yoo, Kyeong Sook Cha, Jong Rim Choi, Ji Yeon Choi, Si Hyeon Han, Jin Ju Park, Tark Kim, Jacob Lee

{"title":"The prevention and response to infectious diseases in long-term care facilities in Korea: a nationwide survey.","authors":"Sun Hee Na, Joong Sik Eom, Sun Bean Kim, Hyung Jin Yoon, So Yeon Yoo, Kyeong Sook Cha, Jong Rim Choi, Ji Yeon Choi, Si Hyeon Han, Jin Ju Park, Tark Kim, Jacob Lee","doi":"10.4178/epih.e2024084","DOIUrl":"https://doi.org/10.4178/epih.e2024084","url":null,"abstract":"Objectives: Long-term care facilities (LTCFs) are communal environments for patients with chronic diseases or older adults, making them particularly susceptible to significant harm during infectious disease outbreaks. Nonetheless, LTCFs have historically been subject to less stringent infection prevention and control (IPC) mandates. This study aimed to assess the current state of LTCFs and to develop an IPC system tailored for these facilities following the coronavirus disease 2019 (COVID-19) pandemic.Methods: We conducted an online survey of 11,366 LTCFs in Korea from December 30, 2022 to January 20, 2023, to evaluate the components of IPC in LTCFs. The infectious diseases targeted for IPC included COVID-19, influenza, and scabies. Additionally, we compared institution-based and home-based long-term care insurance facilities.Results: Overall, 3,537 (31.1%) LTCFs responded to the survey, comprising 1,819 (51.4%) institution-based and 1,718 (48.6%) home-based facilities. A majority (87.4%, 2,376/2,720) of these facilities experienced COVID-19 outbreaks. However, only 42% of home-based facilities, in contrast to 90.6% of institution-based facilities, were equipped to manage concurrent COVID-19 cases. Similarly, while 92.1% of institution-based facilities were capable of managing influenza, only 50.5% of home-based facilities could do the same. The incidence of scabies was significantly higher in institution-based facilities than in home-based ones (26.1% vs. 4.3%). Additionally, 88.7% of institution-based facilities managed scabies cases effectively, compared to only 42.1% of home-based facilities.Conclusion: Approximately half of the LTCFs had a basic capacity to respond to infectious diseases. However, there were differences in response capabilities between institution-based facilities and home-based facilities.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2024084"},"PeriodicalIF":2.2,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex-specific associations between dietary legume subtypes and type 2 diabetes in a prospective cohort study. 前瞻性队列研究中膳食豆类亚型与 2 型糖尿病之间的性别特异性关联。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2024-10-17 DOI: 10.4178/epih.e2024083

Hye Won Woo, Sangmo Hong, Min-Ho Shin, Sang Baek Koh, Hyeon Chang Kim, Yu-Mi Kim, Mi Kyung Kim

{"title":"Sex-specific associations between dietary legume subtypes and type 2 diabetes in a prospective cohort study.","authors":"Hye Won Woo, Sangmo Hong, Min-Ho Shin, Sang Baek Koh, Hyeon Chang Kim, Yu-Mi Kim, Mi Kyung Kim","doi":"10.4178/epih.e2024083","DOIUrl":"https://doi.org/10.4178/epih.e2024083","url":null,"abstract":"Objectives: Dietary soy, known for its high phytoestrogen content, has been suggested to exhibit a sex-specific association with type 2 diabetes. However, evidence regarding the sex-specific associations of different legume subtypes with type 2 diabetes remains scarce. We aimed to evaluate whether habitual consumption of soy and non-soy legumes (beans and peanuts) was prospectively and sex-specifically associated with the risk of type 2 diabetes incidence, taking into considering significant sex-specific genetic factors beyond legume consumption.Methods: A total of 16,666 participants (96,945 person-years) were followed and 945 incident cases were observed. Cumulative intake of legume subtypes was calculated using a food frequency questionnaire administered at baseline and during the revisit surveys.Results: Non-soy legumes are inversely associated with type 2 diabetes in both men and women. Dietary soy intake, however, demonstrated a unilaterally interacting sex-specific association with type 2 diabetes risk (pinteraction for sex=0.0173). Specifically, there was a significant inverse association with type 2 diabetes risk in women (incidence rate ratio, 0.66; 95% confidence interval, 0.48 to 0.80; ptrend=0.0066), but no such association was observed in men. This sex-specific association persisted and even appeared antagonistic in minor allele carriers of 2 novel single nucleotide polymorphisms, rs10196939 (LRRTM4) and rs11750158 (near GFPT2) (pinteraction for sex=0.0014 and 0.0112, respectively).Conclusion: Habitual consumption of legumes shows protective impacts against type 2 diabetes, although these benefits vary by sex. Non-soy legumes provide health advantages for both men and women, whereas soy consumption seems to be beneficial exclusively for women.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2024083"},"PeriodicalIF":2.2,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between the safety climate and occupational injury in the Korean working population: a cross-sectional study. 韩国劳动人口的安全氛围与工伤之间的关系：一项横断面研究。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2024-10-01 DOI: 10.4178/epih.e2024082

Jeehee Min, Tae-Won Jang, Hye-Eun Lee, Mo-Yeol Kang, Seong-Sik Cho

{"title":"Association between the safety climate and occupational injury in the Korean working population: a cross-sectional study.","authors":"Jeehee Min, Tae-Won Jang, Hye-Eun Lee, Mo-Yeol Kang, Seong-Sik Cho","doi":"10.4178/epih.e2024082","DOIUrl":"https://doi.org/10.4178/epih.e2024082","url":null,"abstract":"Objectives: Preventing occupational injuries remains a significant challenge in Korea. A positive safety climate can contribute to reducing workplace injuries. However, the impact of safety climate on preventing occupational injuries among the Korean workforce has not been adequately explored. Therefore, this study aimed to investigate the relationship between the perceived safety climate and occupational injuries within the Korean working population.Methods: This study used baseline data from the Korean Work, Sleep, and Health Study (KWSH). The safety climate was measured using the brief version of the Nordic Safety Climate Questionnaire. Occupational injury was determined by whether injuries or accidents had occurred at workplaces in the past year. Logistic regression analysis was performed to examine the association between the safety climate and occupational injury.Results: Participants who reported an unfavorable workplace safety climate were more likely to experience occupational injuries. Multiple logistic regression analysis revealed that the adjusted odds ratio (OR) for occupational injuries in an unfavorable safety climate was 2.20 (95% confidence interval [CI], 1.38-3.51) compared to a favorable safety climate. Specifically, factors such as \"not encouraging employees to follow safety rules when on a tight schedule\" (OR, 2.02; 95% CI, 1.25-3.24) and \"not helping each other work safely\" (OR, 1.98; 95% CI, 1.17-3.25) were significantly associated with occupational injuries.Conclusion: An unfavorable safety climate was associated with increased occupational injuries among Korean workers. Improving the safety climate in the workplace may reduce occupational injuries in Korea.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2024082"},"PeriodicalIF":2.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142373277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Temporal trends in the prevalence, incidence, and mortality of cardiac amyloidosis in South Korea over 12 years. 韩国 12 年间心脏淀粉样变性的流行率、发病率和死亡率的时间趋势。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2024-09-15 DOI: 10.4178/epih.e2024078

You-Jung Choi, Yun Jin Choi, Ji Eun Lee, Jah Yeon Choi, Geum Joon Cho, Jin Oh Na

{"title":"Temporal trends in the prevalence, incidence, and mortality of cardiac amyloidosis in South Korea over 12 years.","authors":"You-Jung Choi, Yun Jin Choi, Ji Eun Lee, Jah Yeon Choi, Geum Joon Cho, Jin Oh Na","doi":"10.4178/epih.e2024078","DOIUrl":"https://doi.org/10.4178/epih.e2024078","url":null,"abstract":"Objectives: This study investigated the prevalence, incidence, and prognosis of cardiac amyloidosis (CA) in South Korea.Methods: This retrospective nationwide population-based study used the Health Insurance Review and Assessment Service databases between 2008 and 2020. All patients diagnosed with amyloidosis were included, and those with a diagnosis of heart failure or cardiomyopathy were classified as having CA. Both the special code for amyloidosis (V121), which enables coverage of medical expenses, and the corresponding International Classification of Diseases, 10th Revision codes for amyloidosis (E850-E854, E858, E859) were used to improve the reliability of amyloidosis diagnosis.Results: Among 2,239 patients with amyloidosis, 758 met the criteria for CA (mean age, 64.4±11.9 years; 59.1% male). The mean age of patients with CA increased from 59.5±14.7 years in 2009 to 68.1±13.9 years in 2020. The incidence and prevalence increased from 0.09 (95% confidence interval [CI], 0.06-0.12) to 0.22 (95% CI, 0.18-0.27) per 100,000 person-years and 0.20 (95% CI, 0.16-0.25) to 1.30 (95% CI, 0.12-0.42) per 100,000 persons, respectively (all p<0.001). Patients with light-chain CA showed similar trends. In-hospital mortality decreased from 17.3% (95% CI, 9.23%-29.6%) to 6.1% (95% CI, 4.21%-8.48%) between 2009 and 2020. While age-specific in-hospital mortality was significantly higher in patients aged ≥70 years (p=0.004), no significant age-specific difference in in-hospital mortality was observed in patients with CA aged <70 years (p=0.981).Conclusion: The prevalence and incidence of CA have increased in South Korea, predominantly affecting older individuals, particularly males. Notably, in-hospital mortality decreased significantly.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2024078"},"PeriodicalIF":2.2,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142356155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of body mass index and waist-to-hip ratio on mortality in middle-aged Koreans: A prospective cohort study based on a Health Examinees study. 体重指数和腰臀比对韩国中年人死亡率的影响：基于健康体检者研究的前瞻性队列研究。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2024-09-02 DOI: 10.4178/epih.e2024073

Sooyoung Cho, Aesun Shin, Ji-Yeob Choi, Jong-Koo Lee, Daehee Kang

{"title":"Impact of body mass index and waist-to-hip ratio on mortality in middle-aged Koreans: A prospective cohort study based on a Health Examinees study.","authors":"Sooyoung Cho, Aesun Shin, Ji-Yeob Choi, Jong-Koo Lee, Daehee Kang","doi":"10.4178/epih.e2024073","DOIUrl":"https://doi.org/10.4178/epih.e2024073","url":null,"abstract":"Objectives: We aimed to assess the impact of obesity on mortality in middle-aged Koreans using data from a Health Examinees study.Methods: We used data from the participants who had complete information on body size and gave informed consent for the linkage of their data with the national death certificate data. Cox proportional hazard model was used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) of body mass index (BMI) and waist-to-hip ratio (WHR) for all-cause, cardiovascular, and cancer mortality.Results: A total of 115,961 participants were included in the study. The results showed a U-shaped association between BMI and mortality, indicating that both men and women with BMIs of less than 21 kg/m2 and greater than or equal to 30 kg/m2 are at increased risk. The results showed that men with a BMI of less than 18.5 kg/m² had a significantly higher risk of all-cause mortality (adjusted HR: 2.24 [95% CI: 1.73-2.91]) and cardiovascular mortality (2.27 [1.23-4.20]). Similarly, men with a WHR of less than 0.80 (1.38 [1.08-1.77]), 0.90 to less than 0.95 (1.15 [1.02-1.29]), and greater than or equal to 0.95 (1.28 [1.11-1.47]) showed an increased risk of all-cause mortality. In women, a BMI of less than 18 kg/m² was linked to a higher risk of cardiovascular mortality (2.67 [1.13-6.33]).Conclusion: Being underweight was associated with an increased risk of mortality in both sexes, and the lowest risk of death was found in men who were slightly overweight with a BMI of 23-25 kg/m2.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2024073"},"PeriodicalIF":2.2,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0