Epidemiology and Health最新文献

The Korean National Codes Against Cancer: background of their establishment and the revision process. 韩国国家癌症法规：制定背景和修订过程。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2025-05-14 DOI: 10.4178/epih.e2025027

Yoonjoo Choi, Jin-Kyoung Oh, Ayoung Byeon, Byungmi Kim

{"title":"The Korean National Codes Against Cancer: background of their establishment and the revision process.","authors":"Yoonjoo Choi, Jin-Kyoung Oh, Ayoung Byeon, Byungmi Kim","doi":"10.4178/epih.e2025027","DOIUrl":"https://doi.org/10.4178/epih.e2025027","url":null,"abstract":"Objectives: The Korean National Codes Against Cancer provide guidelines for cancer prevention. The inaugural edition was published in 2006, followed by a major revision in 2016. This study aimed to describe the historical context, scientific rationale, and revision process of these guidelines.Methods: With rising cancer incidence in the early 2000s, the Korean government recognized the need for national cancer prevention guidelines, prompting the National Cancer Center to initiate their formulation. The Division of Cancer Prevention reviewed global literature on cancer trends and Korea-specific studies on cancer risk factors. The final set of 10 recommendations comprising the Korean National Codes Against Cancer was approved by the National Cancer Control Committee after achieving expert consensus on cancer prevention.Results: The finalized guidelines are firmly grounded in scientific evidence. The 10 current recommendations include: (1) no smoking and avoidance of secondhand smoke; (2) consuming sufficient fruits and vegetables as part of a balanced diet; (3) reducing salt intake and avoiding burnt or charred foods; (4) limiting alcohol consumption; (5) engaging in regular physical activity (at least 30 minutes a day, 5 days a week); (6) maintaining a healthy body weight; (7) receiving immunization against hepatitis B virus and human papillomavirus; (8) practicing safe sex by maintaining a single sexual partner and using condoms; (9) following health and safety guidelines to avoid exposure to occupational carcinogens; and (10) undergoing regular cancer screening.Conclusion: This study detailed the sources and procedures involved in formulating and revising the Korean National Codes Against Cancer.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2025027"},"PeriodicalIF":2.2,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adherence to the Korean National Code Against Cancer and mortality: a prospective cohort study from the Health Examinees-Gem study. 遵守韩国国家癌症法典和死亡率：来自健康考生gem研究的前瞻性队列研究

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2025-05-09 DOI: 10.4178/epih.e2025026

Jeeyoo Lee, Aesun Shin, Woo-Kyoung Shin, Ji-Yeob Choi, Daehee Kang

{"title":"Adherence to the Korean National Code Against Cancer and mortality: a prospective cohort study from the Health Examinees-Gem study.","authors":"Jeeyoo Lee, Aesun Shin, Woo-Kyoung Shin, Ji-Yeob Choi, Daehee Kang","doi":"10.4178/epih.e2025026","DOIUrl":"https://doi.org/10.4178/epih.e2025026","url":null,"abstract":"Objectives: The Korean National Code Against Cancer was released in 2006. These guidelines aimed to promote a healthy lifestyle to prevent cancer risk through 10 recommendations. The objective of this study was to investigate the associations between adherence to the Korean National Code Against Cancer and the risk of all-cause, cancer, and cardiovascular disease (CVD) mortality among Koreans.Methods: This prospective cohort study included 109,160 Korean adults aged 40 to 69 years, recruited from 2004 to 2013 in the population-based Health Examinees-Gem Study (HEXA-G). The adherence total score was calculated based on 6 items from the Korean National Code Against Cancer: smoking, consuming vegetables and fruits, limiting salty foods, restricting alcohol intake, engaging in physical activity, and maintaining a healthy weight. Hazard ratios (HRs) and 95% confidence intervals (CIs) for the associations of adherence scores with mortality risk were estimated using a Cox proportional hazards regression model.Results: During a mean follow-up period of 12.0 years, 3,799 deaths were recorded. According to the multivariable-adjusted model, men in the highest tertile of adherence scores had a lower risk of all-cause, cancer, and CVD mortality compared to those in the lowest tertile (all-cause: HR=0.67, 95% CI=0.60-0.74; cancer: HR=0.63, 95% CI=0.54-0.74; CVD: HR=0.56, 95% CI=0.43-0.73). A similar association was observed among women for all-cause and CVD mortality (all-cause: HR=0.85, 95% CI=0.76-0.96; CVD: HR=0.70, 95% CI=0.51-0.97).Conclusion: Adherence to the Korean National Code Against Cancer was associated with a reduced risk of all-cause, cancer, and CVD mortality.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2025026"},"PeriodicalIF":2.2,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Social capital and regional influences: key predictors of unmet dental care needs among older adults in South Korea. 社会资本和地区影响：韩国老年人未满足牙科保健需求的关键预测因素。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2025-05-07 DOI: 10.4178/epih.e2025025

Ji-Yeon Lim, Ju-Mi Lee, Hae-Sung Nam

{"title":"Social capital and regional influences: key predictors of unmet dental care needs among older adults in South Korea.","authors":"Ji-Yeon Lim, Ju-Mi Lee, Hae-Sung Nam","doi":"10.4178/epih.e2025025","DOIUrl":"https://doi.org/10.4178/epih.e2025025","url":null,"abstract":"Objectives: Access to dental services is essential for improving quality of life, and social capital plays a key role in facilitating that access. This study aimed to identify individual- and regional-level factors, including social capital, that predict unmet dental care needs among older adults.Methods: We analyzed data from 59,414 older adults obtained from the 2023 Korea Community Health Survey and the Korean Statistical Information Service, employing a 2-level multilevel model. The dependent variables comprised 3 types of unmet dental care needs: overall, due to lack of acceptability, and due to economic reasons. Twelve independent variables, including social capital and other individual and regional factors, were examined.Results: The prevalence of unmet needs was 14.15% overall, 8.70% for acceptability reasons, and 4.85% for economic reasons. Lower individual social capital was associated with higher odds of unmet dental care needs, whereas regional social capital factors demonstrated no significant association. Residing in regions with higher fiscal independence ratios was related to an increased likelihood of economic unmet needs (odds ratio [OR], 1.29; 95% confidence interval [CI], 1.09 to 1.52). In contrast, a greater density of dentists per 10,000 population was inversely associated with overall and acceptability-related unmet needs (OR, 0.82 for both; 95% CI, 0.73 to 0.92 and 0.73 to 0.93, respectively).Conclusion: Individual social capital and specific regional factors-namely, fiscal independence and density of dentists-may represent important determinants of unmet dental care needs among older adults. Policy interventions aimed at reducing unmet needs should consider these variables.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2025025"},"PeriodicalIF":2.2,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk of new-onset seizures following immunization against COVID-19: a self-controlled case-series study. COVID-19免疫接种后新发癫痫发作的风险：一项自我对照病例系列研究

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2025-05-02 DOI: 10.4178/epih.e2025024

Hwa Yeon Ko, Dongwon Yoon, Ju Hwan Kim, Han Eol Jeong, Seung Bong Hong, Won Chul Shin, Ju Young Shin

{"title":"Risk of new-onset seizures following immunization against COVID-19: a self-controlled case-series study.","authors":"Hwa Yeon Ko, Dongwon Yoon, Ju Hwan Kim, Han Eol Jeong, Seung Bong Hong, Won Chul Shin, Ju Young Shin","doi":"10.4178/epih.e2025024","DOIUrl":"https://doi.org/10.4178/epih.e2025024","url":null,"abstract":"Objectives: Despite emerging reports of new-onset seizures (NOS) following COVID-19 vaccination, safety evidence regarding the risk of NOS after vaccination remains limited. We aimed to investigate the potential association between NOS and COVID-19 vaccination.Methods: We conducted a self-controlled case series study utilizing a nationwide database linking the COVID-19 vaccination registry and the National Health Information Database (from February 2021 to October 2022). We identified adults (≥18 years) who received COVID-19 vaccination (BNT162b2, ChAdOx1 nCoV-19, mRNA-1273, NVX-CoV2373, or Ad26.COV2.S) and had a diagnosis of NOS accompanied by prescriptions of anti-seizure drugs. The observation period was defined as 240 days following vaccination. We evaluated the risk of NOS during a risk window of 28 days after vaccination compared to the control window (the remaining observation period excluding the risk window). Incidence rate ratios (IRRs) with 95% confidence intervals (CIs) were estimated using a conditional Poisson regression model.Results: Among 42,155,198 COVID-19 vaccine recipients, we identified 1,849 and 4,217 patients with NOS in the risk and control windows, respectively. There was no increased risk of NOS within the 28-day period following vaccination (IRR, 0.99; 95% CI, 0.94-1.05). Although results from subgroup analyses by vaccine type were largely consistent with the main findings (IRR, 0.95; 95% CI, 0.88-1.03 for BNT162b2; IRR, 0.95; 95% CI, 0.77-1.16 for ChAdOx1 nCoV-19; IRR, 1.58; 95% CI, 0.52-4.83 for Ad26.COV2.S), a marginally elevated risk was observed for mRNA-1273 (IRR, 1.21; 95% CI, 1.04-1.42).Conclusion: There was no evidence of an increased risk of NOS following COVID-19 vaccination. These findings can be used as safety evidence in clinical decision-making and to bolster public confidence in COVID-19 vaccines. .","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2025024"},"PeriodicalIF":2.2,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between humidifier disinfectant use duration and lung cancer development in the Republic of Korea. 韩国加湿器消毒剂使用时间与肺癌发展之间的关系。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2025-05-02 DOI: 10.4178/epih.e2025023

Sungchan Kang, Jeong-In Hwang, Su Hwan Kim, Hyungryul Lim, Dong-Wook Lee, Woojoo Lee, Jong Hun Kim, Sol Yu, Jungyun Lim, Younghee Kim, Kyoung-Nam Kim

{"title":"Association between humidifier disinfectant use duration and lung cancer development in the Republic of Korea.","authors":"Sungchan Kang, Jeong-In Hwang, Su Hwan Kim, Hyungryul Lim, Dong-Wook Lee, Woojoo Lee, Jong Hun Kim, Sol Yu, Jungyun Lim, Younghee Kim, Kyoung-Nam Kim","doi":"10.4178/epih.e2025023","DOIUrl":"https://doi.org/10.4178/epih.e2025023","url":null,"abstract":"Objectives: This study was conducted to assess the association between the duration of humidifier disinfectant use and lung cancer development.Methods: We analyzed data from 3,605 applicants registered for compensation from the Korean government due to health conditions related to humidifier disinfectant exposure. Among these individuals, 121 were diagnosed with lung cancer at least 4 years after their initial exposure (through December 2021). Hazard ratios (HRs) and 95% confidence intervals (CIs) for lung cancer incidence were estimated according to the duration of disinfectant use using Cox proportional hazards models.Results: Compared with <5 months of use, the HRs for lung cancer were 1.81 (95% CI, 0.41 to 7.97) for 5-14 months, 2.45 (95% CI, 0.58 to 10.41) for 15-29 months, and 4.61 (95% CI, 1.12 to 18.91) for ≥30 months. Using never smokers with <15 months of use as the reference category, the HRs were 2.97 (95% CI, 1.34 to 6.56) for never smokers with ≥15 months of use, 2.73 (95% CI, 0.94 to 7.95) for current or former smokers with <15 months of use, and 4.74 (95% CI, 1.94 to 11.61) for current or former smokers with 15 months of use.Conclusion: Our study provides some of the first robust epidemiological evidence that prolonged humidifier disinfectant use contributes to lung cancer development. Future studies-particularly those including unexposed populations-are needed to confirm these findings.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2025023"},"PeriodicalIF":2.2,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inequality in mortality according to regional deprivation during the COVID-19 pandemic. COVID-19大流行期间，区域贫困导致的死亡率不平等。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2025-04-29 DOI: 10.4178/epih.e2025022

Min Hui Moon, Min-Hyeok Choi, Young Gyu Ko

{"title":"Inequality in mortality according to regional deprivation during the COVID-19 pandemic.","authors":"Min Hui Moon, Min-Hyeok Choi, Young Gyu Ko","doi":"10.4178/epih.e2025022","DOIUrl":"https://doi.org/10.4178/epih.e2025022","url":null,"abstract":"Objectives: Vulnerability to coronavirus disease 2019 (COVID-19) is significantly greater in regions with lower socioeconomic status. However, detailed analyses of regional socioeconomic disparities have rarely been conducted in South Korea. This study aimed to identify and compare mortality inequalities associated with regional socioeconomic status across different areas of South Korea during the COVID-19 pandemic.Methods: Using cause-of-death statistics from 2020 to 2022, we calculated age-standardized mortality rates (ASMRs) for total mortality, COVID-19 mortality, and pneumonia mortality. The socioeconomic status of each region was assessed using the regional deprivation index. Additionally, we calculated the rate difference (RD), rate ratio (RR), slope index of inequality (SII), and relative index of inequality (RII) for each socioeconomic level to examine the extent of mortality inequality and its temporal changes. These analyses were stratified by sex and urban-rural classification.Results: The total mortality rate, as well as COVID-19-specific and pneumonia-specific mortality rates, increased during the COVID-19 pandemic. The ASMR for COVID-19 was higher in rural areas (ASMR, 27.79), which have lower healthcare accessibility, compared to urban areas (ASMR, 26.63). However, mortality inequality indicators for COVID-19 were more pronounced in urban areas compared to rural areas (SII [urban: 2.72; rural: -0.05], RII [urban: 0.10; rural: 0.00]). Notably, significant inequalities were observed among men residing in urban areas.Conclusion: In disaster situations such as the COVID-19 pandemic, it is essential to implement strategies aimed at reducing overall mortality rates and addressing regional socioeconomic inequalities.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2025022"},"PeriodicalIF":2.2,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Geospatial analysis of neonatal mortality in North-eastern India: a multilevel Bayesian approach. 印度东北部新生儿死亡率的地理空间分析：多层次贝叶斯方法。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2025-04-27 DOI: 10.4178/epih.e2025021

Vidhi Jain, Kh Jitenkumar Singh, Deboshree Das, Shefali Gupta, Gunjan Singh

{"title":"Geospatial analysis of neonatal mortality in North-eastern India: a multilevel Bayesian approach.","authors":"Vidhi Jain, Kh Jitenkumar Singh, Deboshree Das, Shefali Gupta, Gunjan Singh","doi":"10.4178/epih.e2025021","DOIUrl":"https://doi.org/10.4178/epih.e2025021","url":null,"abstract":"Objectives: Neonatal mortality remains a significant public health issue in India. This study investigates spatial patterns and contributing factors to neonatal mortality in the north-eastern states, identifying hotspot regions and spatial variations.Methods: A sample of 34,222 mothers from NFHS-5 (2019-21) in the north-eastern states was analysed. Descriptive and bivariate analyses were conducted alongside Bayesian multilevel logistic regression using Integrated Nested Laplace Approximation (INLA) to model neonatal mortality. Spatial hotspot analysis using Getis-Ord Gi* statistics identified clusters of high neonatal mortality, while geographically weighted regression (GWR) was used to examine spatial variations in the relationships between neonatal mortality and contributing factors.Results: The neonatal mortality rate in the north-eastern states declined from 45 to 21 per 1,000 live births (NFHS-1 to NFHS-5) but remains higher than the national average. Assam reported the highest mortality (42.16%), whereas Sikkim had the lowest (0.87%). Higher mortality was observed among male infants, mothers with advanced age, low maternal education, and mothers who attended less than 5 antenatal care (ANC) visits. Spatial analysis identified hotspots in Assam, Meghalaya, and Tripura. GWR indicated that areas with less than 5 ANC visits had the strongest association with neonatal mortality. Bayesian multilevel analysis highlighted spatial variations of up to 51% across districts in northeast India.Conclusion: This study underscores spatial disparities in neonatal mortality across north-eastern India. Addressing childcare practices and healthcare access in hotspot regions is essential for improving new-born health outcomes. The findings provide critical insights for policymakers to develop targeted interventions aimed at reducing neonatal mortality in these underserved areas.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2025021"},"PeriodicalIF":2.2,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between regular dental scaling and stroke risk in patients with periodontal diseases: evidence from a Korean nationwide database. 牙周病患者定期刮牙与中风风险之间的关系：来自韩国全国数据库的证据

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2025-04-19 DOI: 10.4178/epih.e2025020

Yu-Rin Kim, Minkook Son, Seon-Rye Kim

{"title":"Association between regular dental scaling and stroke risk in patients with periodontal diseases: evidence from a Korean nationwide database.","authors":"Yu-Rin Kim, Minkook Son, Seon-Rye Kim","doi":"10.4178/epih.e2025020","DOIUrl":"https://doi.org/10.4178/epih.e2025020","url":null,"abstract":"Objectives: This study aimed to evaluate the association between the frequency of dental scaling and the risk of stroke among individuals with moderate-to-severe periodontal diseases and verify the effect of regular dental scaling on stroke risk in this population.Methods: In this retrospective study, 25,758 subjects with moderate-to-severe periodontal diseases were selected from the Korean National Health Insurance Service-National Health Screening cohort database. Based on the frequency of dental scaling, the subjects were divided into three groups: regular, occasional, and infrequent. Restricted cubic splines were used to evaluate hazard ratios (HR) with 95% confidence intervals (CI) for stroke. Additionally, landmark analysis was conducted to strengthen the reliability of the Results.Results: There were 293, 111, and 38 stroke cases in the infrequent, occasional, and regular group, respectively. The adjusted HR for stroke in the regular group, compared to that in the infrequent group, was 0.40 (95% CI, 0.29-0.57). In the landmark analysis with follow-up after 1 year and after 2 years, the adjusted HR in the regular group compared to that in the infrequent group was 0.41 (95% CI, 0.28-0.60) and 0.50 (95% CI, 0.33-0.76), respectively.Conclusion: Regular dental scaling was significantly associated with a reduced risk of stroke in patients with moderate-to-severe periodontal diseases. These findings may suggest a potential preventive role of dental scaling beyond oral health. Further studies are needed to explore the underlying biological mechanisms linking periodontal care to stroke prevention and to explore causal relationships between dental scaling and stroke risk.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2025020"},"PeriodicalIF":2.2,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of hypertension-related avoidable hospitalization on all-cause mortality in older patients with hypertension: a nationwide retrospective cohort study in South Korea. 与高血压相关的可避免住院治疗对老年高血压患者全因死亡率的影响：韩国一项全国性回顾性队列研究

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2025-04-18 DOI: 10.4178/epih.e2025019

Yehrhee Son, Noorhee Son, Sungyoun Chun, Ki-Bong Yoo, Jung Hyun Chang, Woo-Ri Lee

{"title":"Impact of hypertension-related avoidable hospitalization on all-cause mortality in older patients with hypertension: a nationwide retrospective cohort study in South Korea.","authors":"Yehrhee Son, Noorhee Son, Sungyoun Chun, Ki-Bong Yoo, Jung Hyun Chang, Woo-Ri Lee","doi":"10.4178/epih.e2025019","DOIUrl":"https://doi.org/10.4178/epih.e2025019","url":null,"abstract":"Objectives: The prevalence of hypertension is increasing as a result of rapid population aging, which elevates the societal burden of the disease. In South Korea, the hospitalization rate for hypertension-related admissions exceeds the average reported by the Organization for Economic Co-operation and Development; however, the impact of these hospitalizations has not been evaluated. Therefore, this study investigates the association between hypertension-related avoidable hospitalizations and all-cause mortality.Methods: We included patients aged ≥60 years diagnosed with hypertension, identified using data from the National Health Insurance Services Senior Cohort spanning 2008 to 2019. The primary outcome was all-cause mortality measured at 3 and 5 years after the hypertension diagnosis. The key independent variable was the incidence of hypertension-related avoidable hospitalizations within the first year following the initial hypertension diagnosis. Cox proportional hazards regression analysis was employed to assess these associations. To ensure robust findings and minimize selection bias, several sensitivity analyses were conducted.Results: Out of 65,686 participants, 397 (0.6%) experienced hypertension-related avoidable hospitalizations within 1 year of their initial hypertension diagnosis. Individuals who experienced such hospitalizations had a significantly higher risk of all-cause mortality compared to those who did not (3-year: hazard ratio (HR) 2.12, 95% confidence interval (CI) 1.53-2.94; 5-year: HR, 2.13; 95% CI, 1.68-2.68).Conclusion: Hypertension-related avoidable hospitalizations among older adults are associated with an increased risk of both short-term and long-term all-cause mortality. These findings underscore the importance of timely hypertension management to prevent such hospitalizations.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2025019"},"PeriodicalIF":2.2,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parents' employment and non-chromosomal congenital anomalies in South Korea: a national population cohort study. 韩国父母就业与非染色体先天性异常：一项全国人口队列研究。

IF 2.2 4区医学

Epidemiology and Health Pub Date : 2025-04-10 DOI: 10.4178/epih.e2025018

Kyuwon Kim, Hoyol Jhang, Erdenetuya Bolormaa, Chae Bong Kim, Seung-Ah Choe

{"title":"Parents' employment and non-chromosomal congenital anomalies in South Korea: a national population cohort study.","authors":"Kyuwon Kim, Hoyol Jhang, Erdenetuya Bolormaa, Chae Bong Kim, Seung-Ah Choe","doi":"10.4178/epih.e2025018","DOIUrl":"https://doi.org/10.4178/epih.e2025018","url":null,"abstract":"Objectives: We assessed the association between parents' employment status, including industrial classification, and non-chromosomal congenital anomalies in offspring.Methods: We analyzed data from mothers who delivered live births between 2020 and 2022, linking their records with those of their neonates from the National Health Information Service (NHIS) database. Our analysis focused on common industrial classifications representing at least 6% of the total workforce. Congenital anomalies were identified based on neonates' diagnostic codes. We conducted logistic regression to estimate odds ratios (ORs) of congenital anomalies by the industrial classification of mothers and their partners, adjusting for individual risk factors, with the financial industry serving as the reference category.Results: Among 338,637 women with a live birth, 148,818 (43.9%) were employed at the time of pregnancy. Employment was associated with a higher risk of congenital anomalies (OR, 1.08; 95% confidence interval [CI], 1.04-1.12). Within the common industrial classifications, health and social work exhibited the highest risk (OR, 1.11; 95% CI, 1.06-1.22) compared to the financial industry. Women employed in general hospitals showed particularly elevated risks (OR, 1.19; 95% CI, 1.04-1.37). Among male partners, the risk estimates were generally imprecise.Conclusion: The study indicates that certain industries are linked with a higher risk of congenital anomalies among women workers. These findings underscore the need for enhanced safety measures in high-risk industrial settings to reduce the occurrence of congenital anomalies.","PeriodicalId":48543,"journal":{"name":"Epidemiology and Health","volume":" ","pages":"e2025018"},"PeriodicalIF":2.2,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0