Nutrition Bulletin最新文献

{"title":"MUSAE: Fusion of art and technology to address challenges in food and health.","authors":"Aoife O'Gorman, McMahon Lauryn, Tatiana Efremenko, Marita Canina, Petia Ivanova Redava, Luis Eloy Puig, Angelo Cangelosi, Francesco Ferro, Francesco Dellino, Ramona Van Gansbeke, Maria Bulgheroni, Kosta Jovanovic, Lorraine Brennan","doi":"10.1111/nbu.12723","DOIUrl":"10.1111/nbu.12723","url":null,"abstract":"<p><p>There is an urgent need to transform our current food system to improve population health/wellbeing and planetary health. A number of challenges exist in order to achieve this. Artists, with their innate ability to use imagination to envision future needs and solve problems, represent a key group in this transformation. The project MUSAE brings together artists with experts from different disciplines to define an innovative model to integrate artistic collaboration in the (European) Digital innovation hubs (E-DIHs). They will employ the Design Futures Art-Driven (DFA) methods to enable artists and a range of companies involved in food production and distribution to develop innovative products and services that address key issues in the food system. MUSAE will run two residencies involving 23 artists and 11 SMEs working with three main technologies-Artificial Intelligence, Wearables and Robotics-to envision the future scenarios for societal needs and technology applications, as well as develop future-driven prototypes, thus opening new markets and innovations in the area of food.</p>","PeriodicalId":48536,"journal":{"name":"Nutrition Bulletin","volume":" ","pages":"120-131"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11815599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging mechanisms of organ crosstalk: The role of oxylipins.","authors":"Helena Lucy Fisk, Saame Raza Shaikh","doi":"10.1111/nbu.12726","DOIUrl":"10.1111/nbu.12726","url":null,"abstract":"<p><p>There is growing interest in the role of oxylipins in the pathophysiology of several diseases. This is accompanied by a limited but evolving evidence base describing augmented oxylipin concentrations in a range of complications including cardiovascular disease, obesity, liver disease and neurological disorders. Despite this, literature describing oxylipin profiles in blood and multiple organs is inconsistent and the mechanisms by which these profiles are altered, and the relationships between localised tissue and circulating oxylipins are poorly understood. Inflammation and immune response associated with disease requires communication across organs and physiological systems. For example, inflammation and comorbidities associated with obesity extend beyond the adipose tissue and affect the vascular, hepatobiliary and digestive systems amongst others. Communication between organs and physiological systems is implicated in the progression of disease as well as the maintenance of homeostasis. There is emerging evidence for the role of oxylipins as a mechanism of communication in organ crosstalk but the role of these in orchestrating multiple organ and system responses is poorly understood. Herein, we review evidence to support and describe the role of oxylipins in organ crosstalk via the cardiosplenic and gut-link axis. In addition, we review emerging mechanisms of oxylipin regulation, the gut microbiome and modification using nutritional intervention. Finally, we describe future perspectives for addressing challenges in measurement and interpretation of oxylipin research with focus on the host genome as a modifier of oxylipin profiles and response to dietary lipid intervention.</p>","PeriodicalId":48536,"journal":{"name":"Nutrition Bulletin","volume":" ","pages":"12-29"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11815618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of vitamin D status in healthy Bangladeshi urban and rural individuals and their association with serum calcium and alkaline phosphatase: A pilot study.","authors":"Afsana Shahid Priyanka, Tasnim Tabassum Progga, Sabekun Nasher","doi":"10.1111/nbu.12721","DOIUrl":"10.1111/nbu.12721","url":null,"abstract":"<p><p>Vitamin D insufficiency is a worldwide problem that is likely underestimated since physical symptoms may only be apparent in individuals with severe deficiencies. Previously, people in South Asian countries were thought to be vitamin D sufficient because of plentiful sunshine, but vitamin D insufficiency has also been reported in these countries. In a South Asian country like Bangladesh, people living in the rural and urban parts of the country can have considerable differences in their sun exposure, types of clothing worn, and levels of air pollution. This pilot study aimed to explore the vitamin D status (measured by serum 25[OH]D) of healthy urban and rural Bangladeshi people and to examine the association of serum 25(OH)D concentration with calcium and alkaline phosphatase concentrations. A total of 101 apparently healthy adult individuals, aged 20-58 years, were enrolled from both urban and rural areas. The participants were selected from students, staff and patient attendants from the outpatient department (OPD) of Bangabandhu Sheikh Mujib Medical University and Mirsarai Upazila Health Complex, Chittagong. The overall rate of vitamin D insufficiency was 39.6% and of vitamin D deficiency was 51.5%. However, it was observed that the proportion of vitamin D-deficient participants in urban areas (70.6%) was more than double that of participants living in rural areas (32%) and that serum 25(OH)D concentrations were higher in rural compared to urban participants with similar sunlight exposure times. However, participants aged 50 years or more showed similar concentrations of serum vitamin D levels irrespective of their habitat. This pilot study highlights the need for further larger-scale studies in Bangladesh to determine the reasons for the high rates of vitamin D inadequacy overall and the differences between rural and urban populations.</p>","PeriodicalId":48536,"journal":{"name":"Nutrition Bulletin","volume":" ","pages":"82-90"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anaemia, overweight and abdominal obesity in mothers and children are associated with the food environment in socially vulnerable areas of a northeastern Brazilian capital.","authors":"Luiz Gonzaga Ribeiro Silva-Neto, Camila Aparecida Borges, Nassib Bezerra Bueno, Thays Lane Ferreira Dos Santos, Risia Cristina Egito de Menezes, Telma Maria de Menezes Toledo Florêncio","doi":"10.1111/nbu.12728","DOIUrl":"10.1111/nbu.12728","url":null,"abstract":"<p><p>This study aimed to assess the association between community and consumer food environment (FE) measures and anaemia, overweight and abdominal obesity in mother-child dyads living in situations of social vulnerability. A cross-sectional study was carried out in 40 favelas in a capital city in the northeast of Brazil. The sample consisted of 1882 women and 665 children aged under 5 years. The community FE was assessed using a scale of perception of the availability of healthy food in the neighbourhood. Consumer FE was assessed by auditing 624 retail food stores using the AUDITNOVA instrument. This investigated various aspects of the food environment and evaluated the availability of 18 ultra-processed foods (UPF) most consumed by the Brazilian population available in these stores. The presence of overweight was assessed by measuring the weight and height of the mother and the child, and abdominal obesity was assessed by measuring the mother's waist circumference. The presence of anaemia in the mother and the child was assessed by measuring haemoglobin. Adjusted multilevel regression models were used to verify associations between the FE and malnutrition in mother-child dyads. Low perception of community FE was associated with higher risk of women being overweight (OR: 1.35; 95% CI: 1.05-1.73) and abdominally obese (OR: 1.38; 95% CI: 1.04-1.84); low health scores in food shops were associated with higher risk of abdominal obesity (OR: 1.35; 95% CI: 1.01-1.79) and anaemia (OR: 1.16; 95% CI: 1.02-1.98) in women and overweight in children (OR: 1.69; 95% CI: 1.05-2.73); and the high availability of UPF in retail shops was associated with increased odds of overweight (OR: 2.64; 95% CI: 1.61-4.33) and anaemia (OR: 2.11; 95% CI: 1.38-3.02) in children by 164% and 111%, respectively. It was observed that less healthy food environments are associated with greater chances of anaemia, overweight and abdominal obesity in mothers and children under 5 years in situations of social vulnerability in Brazil.</p>","PeriodicalId":48536,"journal":{"name":"Nutrition Bulletin","volume":" ","pages":"91-105"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sarcopenic obesity and brain health: A critical appraisal of the current evidence.","authors":"Uraiporn Booranasuksakul, Zhongyang Guan, Ian A Macdonald, Kostas Tsintzas, Blossom C M Stephan, Mario Siervo","doi":"10.1111/nbu.12725","DOIUrl":"10.1111/nbu.12725","url":null,"abstract":"<p><p>Sarcopenic obesity (SO) is a body composition phenotype derived from the simultaneous presence in the same individual of an increase in fat mass and a decrease in skeletal muscle mass and/or function. Several protocols for the diagnosis of SO have been proposed in the last two decades making prevalence and disease risk estimates of SO heterogeneous and challenging to interpret. Dementia is a complex neurological disorder that significantly impacts patients, carers and healthcare systems. The identification of risk factors for early cognitive impairment and dementia is key to mitigating the forecasted trends of a 2-fold increase in dementia case numbers over the next two decades worldwide. Excess adiposity and sarcopenia have both been independently associated with risk of cognitive impairment and dementia. Whether SO is associated with a greater risk of cognitive impairment and dementia is currently uncertain. This review critically appraises the current evidence on the association between SO with cognitive outcomes and dementia risk. It also discusses some of the putative biological mechanisms that may link the SO phenotype with alteration of brain functions.</p>","PeriodicalId":48536,"journal":{"name":"Nutrition Bulletin","volume":" ","pages":"30-43"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations Between Chrono-Nutrition Behaviours and Cognitive Function in Middle-Aged Adults: The NUTRICO Cross-Sectional Cohort Study.","authors":"Christiana A Demetriou, Dona Hileti, Elisavet Onisiphorou, Christiana Kazafanioti, Marios Alogakos, Dionysia Vardakastani, Erato Christofidou, Eleni P Andreou, Christoforos D Giannaki, Pinelopi S Stavrinou, Philippos Philippou, Fofi Constantinidou, Elena Philippou","doi":"10.1111/nbu.70000","DOIUrl":"https://doi.org/10.1111/nbu.70000","url":null,"abstract":"<p><p>Healthy midlife cognitive function (CF) reduces the risk of later cognitive decline. Emerging evidence suggests that chrono-nutrition may be associated with CF. This cross-sectional cohort study aimed to examine associations between chrono-nutrition behaviours and CF in adults aged 45-65 years living in Cyprus. Chrono-nutrition, including misalignments between actual and preferred eating times, Mediterranean diet (MD) adherence, sleep and physical activity were assessed using validated questionnaires. Computerised neurocognitive remote testing was used to derive standard normalised age-matched scores for composite memory, psychomotor speed, cognitive flexibility, complex attention, reaction time and neurocognitive index. Education, marital status, smoking, body mass index, chronic disease diagnosis and religious fasting were also assessed. Adjusted multivariate ordinal logistic regression was used to assess each chrono-nutrition variable against each cognitive outcome. Two-hundred and seven participants were analysed (58% female, median age: 52 years, 75.6% university graduates). Morning latency (duration of time between one's wake time and first eating event) misalignment was associated with higher neurocognitive index (OR eating later than preferred by 30-90 min: 2.91; 95% CI: 1.33-5.97 and OR eating later than preferred by > 90 min: 2.57; 95% CI: 1.34-4.88) and with higher cognitive flexibility (OR eating later than preferred by 30-90 min: 2.23; 95% CI: 1.07-4.64). An eating window longer than preferred by > 120 min was associated with a lower psychomotor speed (OR: 0.17; 95% CI: 0.04-0.67). Evening eating between 20:00 and 22:59 versus before 20:00 was associated with higher complex attention (OR: 2.07; 95% CI: 1.08-3.97). No evidence was found that eating alignment is associated with better CF. The study provides insights that some chrono-nutrition behaviours may be associated with CF with potential implications for improving CF in middle-aged adults.</p>","PeriodicalId":48536,"journal":{"name":"Nutrition Bulletin","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Impact of Açai (Euterpe oleracea) on Lipid Profile: A Comprehensive Systematic Review and Meta-Analysis.","authors":"Bruno Moreira Candeloro, Túlio H B Bitencourt, Sergio F R Elias, Maria Clara Rauli, Isabela B Brandão, Sandra Maria Barbalho, David M Garner, Rodrigo D Raimundo, Andrey A Porto, Vitor E Valenti","doi":"10.1111/nbu.12735","DOIUrl":"https://doi.org/10.1111/nbu.12735","url":null,"abstract":"<p><p>Conditions such as obesity and cardiovascular diseases represent significant global public health challenges, driven by their increasing prevalence and profound effects on morbidity and mortality. Dyslipidemia, defined by abnormal lipid concentrations, performs a pivotal role in the onset of cardiovascular diseases, especially atherosclerosis. Dietary strategies and other nonpharmacological interventions are crucial for the management of dyslipidemia. Açaí (Euterpe oleracea), a fruit native to the Amazon, is recognised for its antioxidant properties and potential impact on lipid metabolism. This systematic review and meta-analysis aimed to assess the impact of açaí consumption on lipid profile markers. A systematic search was performed across several databases, including MEDLINE/PubMed, EMBASE, Web of Science and Scopus. We included non-randomised, randomised, no blind, blind and control trials involving adult participants who received açaí in any form. The outcome measures included triglycerides, total cholesterol, LDL-c and HDL-c. The screening of studies and data extraction were independently conducted by four reviewers. The risk of bias was evaluated using the Cochrane Risk of Bias tool, and meta-analyses were completed where applicable. Out of 188 identified studies, 8 met the inclusion criteria. Meta-analysis of 411 participants displayed no significant effect of açaí on LDL-c (MD = 6.06 mg/dL 95% CI: -0.03, 12.48, p = 0.06), HDL-c (MD = 0.30 mg/dL 95% CI: -1.54, 2.13, p = 0.75), total cholesterol (MD = 2.94 mg/dL 95% CI: -6.44, 12.31, p = 0.54) and triglycerides (MD = 2.05 mg/dL 95% CI: 1.79, 2.28, p = 0.59). Additionally, açaí consumption was related to a significant reduction in total lipids (MD = -9.80 g, 95% CI: -13.94 to -5.66, p < 0.001). GRADE evaluation pointed to low/very low certainty of evidence. Açaí consumption may lessen total lipid levels, but no significant effect was noted for cholesterol parameters and triglycerides. Further trials with more demanding research methodologies are required to clarify the effects of açaí on lipid profiles. Trial Registration: CRD42024549531.</p>","PeriodicalId":48536,"journal":{"name":"Nutrition Bulletin","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and Perceptions of Supplemental Nutrition Assistance Program-Eligible Purchases: A Survey of US Midwestern College Students.","authors":"Matthew Chrisman, Matthew J Landry, Seth Klobodu, Dylan Bailey","doi":"10.1111/nbu.70002","DOIUrl":"https://doi.org/10.1111/nbu.70002","url":null,"abstract":"<p><p>Little is known regarding the intrastudent barriers to accessing and utilising the Supplemental Nutrition Assistance Program (SNAP). To examine college students' knowledge of allowable items and perception of what items should be allowed for purchase with (SNAP) benefits, particularly by food security status and enrolment in SNAP in the past 12 months, a cross-sectional, online survey was conducted among 844 college students from nine higher education institutions in a single Midwestern state. Many students were unaware that certain food items were already covered by SNAP, leading them to express a desire for these items to be included. Additionally, there were misconceptions about the eligibility of nonfood items for purchase using SNAP benefits. Beyond traditional food items, students highly desired the inclusion of necessities such as toiletries and cooking equipment. Improved outreach and educational campaigns could be developed to clarify the eligible items and scope of the programme, enabling students to make informed decisions about their SNAP benefit usage.</p>","PeriodicalId":48536,"journal":{"name":"Nutrition Bulletin","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Portion Estimation, Satiety Perception and Energy Intake Following Different Breakfast Portion Sizes in Healthy Adults.","authors":"Kinga Kwiecien, Lourdes Santos-Merx, Tarsem Sahota, Helen Coulthard, Mariasole Da Boit","doi":"10.1111/nbu.12733","DOIUrl":"https://doi.org/10.1111/nbu.12733","url":null,"abstract":"<p><p>Expected satiety is a key element in predicting meal portion size and food consumption; however, how this can be affected by different breakfast portion sizes is unknown. The study examined the impact of different breakfast portions on satiety, portion size, and energy intake and comprised an online survey and an experimental intervention. Sixteen adults (9 women, BMI: 24.9 ± 4.3 kg/m²) rated images of three portion sizes (small, standard, large) of the same breakfast using an ordinal scale. Subsequently, they were asked to self-prepare and consume ad libitum the three breakfast portions in a randomised order on different days and to complete a food diary. Satiety and portion size perception were re-measured upon consumption of each breakfast. For both the visual image and breakfast consumption, the small breakfast portion was rated as the smallest and least filling, while the large portion was rated as the largest and most filling (p < 0.05). When consuming the small breakfast, participants reported being hungrier and less full between breakfast and lunch (p < 0.05) and had a higher energy intake from lunch onward, due to more snacking (p < 0.05). However, the total daily energy intake was not different among the three breakfast portion sizes. Individuals seemed accustomed to predicting satiety and portion size from images. The consumption of the small breakfast was judged as not filling enough and was accompanied by a higher energy intake via energy-dense snacks. Based on these preliminary findings, breakfast size reduction may lead to unhealthy compensatory energy intake by snacking on energy-dense foods.</p>","PeriodicalId":48536,"journal":{"name":"Nutrition Bulletin","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics and nutrient profiles of foods and beverages on online food delivery systems.","authors":"Jia-Wen Chin, Wendy Mei Ling Loh, Yasmin Beng Houi Ooi, Ban-Hock Khor","doi":"10.1111/nbu.12727","DOIUrl":"https://doi.org/10.1111/nbu.12727","url":null,"abstract":"<p><p>Recently, there has been an emerging trend of purchasing foods and beverages via online food delivery systems but there is scarce evidence on the healthfulness of these items, particularly in Southeast Asian countries such as Malaysia. This study aimed to evaluate the characteristics and nutrient profiles of foods and beverages available via online food delivery systems in Malaysia. This cross-sectional study was conducted from September 2022 to March 2023 to identify foods and beverages available on the Grab Food and Foodpanda mobile applications. The healthfulness of selected foods and beverages was determined based on the Food Standards Agency Nutrient Profiling System. The present study included 3729 foods and 1882 beverages. Most of the foods were cereal-based dishes (37.4%), followed by cereals with protein-based dishes (12.8%) and meat or poultry-based dishes (12.0%), while most of the beverages were local handcrafted beverages (27.8%), followed by bubble milk tea (15.0%) and Western handcrafted beverages (14.6%). For protein dishes, deep-frying or battered-frying was the most common preparation method (33.8%) while most of the cereal-based dishes were stir-fried (76.7%). Out of 23 common foods, 15 foods (65%) were categorised as less healthy based on the nutrient profile score while 19 out of 24 (79%) common beverages were categorised as less healthy. The online food delivery systems feature predominantly local foods and beverages that are less healthy, potentially contributing to the development of an obesogenic environment.</p>","PeriodicalId":48536,"journal":{"name":"Nutrition Bulletin","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}