Qianqian Ju , Zhijian Xu , Zile Chen , Jiayi Fan , Han Zhang , Yujia Peng
{"title":"Screening social anxiety with the Social Artificial Intelligence Picture System","authors":"Qianqian Ju , Zhijian Xu , Zile Chen , Jiayi Fan , Han Zhang , Yujia Peng","doi":"10.1016/j.janxdis.2024.102955","DOIUrl":"10.1016/j.janxdis.2024.102955","url":null,"abstract":"<div><div>Social anxiety disorder (SAD) is a prevalent anxiety disorder marked by strong fear and avoidance of social scenarios. Early detection of SAD lays the foundation for the introduction of early interventions. However, due to the nature of social avoidance in social anxiety, the screening is challenging in the clinical setting. Classic questionnaires also bear the limitations of subjectivity, memory biases under repeated measures, and cultural influence. Thus, there exists an urgent need to develop a reliable and easily accessible tool to be widely used for social anxiety screening. Here, we developed the Social Artificial Intelligence Picture System (SAIPS) based on generative multi-modal foundation artificial intelligence (AI) models, containing a total of 279 social pictures and 118 control pictures. Social scenarios were constructed to represent core SAD triggers such as fear of negative evaluation, social interactions, and performance anxiety, mapping to specific dimensions of social anxiety to capture its multifaceted nature. Pictures devoid of social interactions were included as a control, aiming to reveal response patterns specific to social scenarios and to improve the system’s precision in predicting social anxiety traits. Through laboratory and online experiments, we collected ratings on SAIPS from five dimensions. Machine learning results showed that ratings on SAIPS robustly reflected and predicted an individual’s trait of social anxiety, especially social anxiety and arousal ratings. The prediction was reliable, even based on a short version with less than 30 pictures. Together, SAIPS may serve as a promising tool to support social anxiety screening and longitudinal predictions.</div></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":"109 ","pages":"Article 102955"},"PeriodicalIF":4.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alainna Wen , Allison V. Metts , Richard E. Zinbarg , Susan Mineka , Michelle G. Craske
{"title":"Tri-level anxiety and depression symptom trajectory in adolescents: The role of emotion regulation diversity","authors":"Alainna Wen , Allison V. Metts , Richard E. Zinbarg , Susan Mineka , Michelle G. Craske","doi":"10.1016/j.janxdis.2024.102941","DOIUrl":"10.1016/j.janxdis.2024.102941","url":null,"abstract":"<div><div>Anxiety and depression are associated with impaired emotion regulation (ER). Recently, a novel construct named ER diversity has been proposed to assess the diversity in ER strategy use. Low ER diversity, particularly under stressful circumstances, may be a transdiagnostic vulnerability factor for anxiety and depression. This study utilized a longitudinal design to examine the association between ER diversity and transdiagnostic anxiety and depressive symptom trajectory in adolescents (<em>N</em> = 627 at baseline), while accounting for life stress. Measures of ER strategy use, chronic interpersonal life stress, neuroticism, and transdiagnostic dimensional symptoms of anxiety and depression were assessed. The ER diversity index and the traditional ER sum score were computed. Higher ER diversity index was associated with steeper decline in the Fears symptom factor over time, above and beyond the ER sum score and neuroticism. Moreover, chronic interpersonal life stress influenced these associations. When chronic interpersonal life stress was low, Fears declined over time regardless of the ER diversity level; when chronic interpersonal life stress was high, Fears only declined when ER diversity was high. Thus, low diversity in ER strategy use, particularly under stressful circumstances, may be a vulnerability factor for fear symptom development.</div></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":"109 ","pages":"Article 102941"},"PeriodicalIF":4.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Silke van Dijk , Kevin van Schie , Tom Smeets , Gaëtan Mertens
{"title":"Limited consensus on what climate anxiety is: Insights from content overlap analysis on 12 questionnaires","authors":"Silke van Dijk , Kevin van Schie , Tom Smeets , Gaëtan Mertens","doi":"10.1016/j.janxdis.2024.102957","DOIUrl":"10.1016/j.janxdis.2024.102957","url":null,"abstract":"<div><div>Climate anxiety is a phenomenon that is gaining importance due to the general public’s increased awareness of the worsening climate crisis. At present, climate anxiety is not operationalized consistently across the existing literature. It is important to gain more consensus on the definition and operationalization of climate anxiety to facilitate reliable and generalizable research and to further develop interventions. Content analysis can contribute to this by providing insight into the overlap in the content of climate anxiety measures. With a systematic search, this study identified and analyzed 12 distinct scales measuring climate anxiety. The 119 items covered a total of 57 disparate symptoms. Jaccard indices showed that the mean overlap between symptoms of different climate anxiety scales was generally very low, as was the overlap between pairwise comparisons of climate anxiety scales. These results highlight the lack of uniformity in assessing climate anxiety and the need to properly define and operationalize this concept. The potential reasons for low overlap and how this might impact the reliability and validity of existing measures are discussed. It is critical that future work aims at finding consensus on the definition of climate anxiety (e.g., through a Delphi study) and psychometrically comparing the different questionnaires.</div></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":"109 ","pages":"Article 102957"},"PeriodicalIF":4.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tom Zalmenson , Noga Yair , Omer Azriel , Dana Shamai-Leshem , Yaron Alon , Niv Tik , Yoav Levinstein , Ariel Ben-Yehuda , Lucian Tatsa-Laur , Daniel S. Pine , Paul D. Bliese , Ido Tavor , Yair Bar-Haim
{"title":"The effects of intelligence on exposure to combat and posttraumatic stress disorder across multiple deployments","authors":"Tom Zalmenson , Noga Yair , Omer Azriel , Dana Shamai-Leshem , Yaron Alon , Niv Tik , Yoav Levinstein , Ariel Ben-Yehuda , Lucian Tatsa-Laur , Daniel S. Pine , Paul D. Bliese , Ido Tavor , Yair Bar-Haim","doi":"10.1016/j.janxdis.2024.102961","DOIUrl":"10.1016/j.janxdis.2024.102961","url":null,"abstract":"<div><h3>Introduction</h3><div>Past work relates intelligence quotient (IQ) to risk for Post-Traumatic Stress Disorder (PTSD) among soldiers. We gathered data over multiple deployments to assess how IQ relates to the rate of symptom development both directly and through increasing the risk for traumatic combat exposure.</div></div><div><h3>Methods</h3><div>Male infantry soldiers from a maneuver brigade (N = 582) were followed over the 3-year period of their mandatory military service. Data were collected at 3-time-points: 1) shortly after enlistment and before deployment; 2) about 15 months into the service following one deployment, and another year later following additional deployments. IQ was measured before recruitment into the military; PTSD symptoms and combat exposure were measured at each time-point.</div></div><div><h3>Results</h3><div>Lower general IQ, and in particular lower abstract reasoning capabilities, related to steeper increases in PTSD symptoms, TIME<strong>×</strong>IQ<strong>=</strong> -.05, SE= .02, t(442.79) = -3.255, p < .01, controlling for the effect of pre-military traumatic experience. This relation was partly mediated by combat exposure, Effect= -.04, BootSE= .01, 95 % CI [-.06, −.02].</div></div><div><h3>Conclusion</h3><div>The results identify important risk factors for PTSD that can inform approaches to PTSD mitigation in the military and other organizations. Given that this study enrolled a male sample the generalizability of the results awaits further research.</div></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":"109 ","pages":"Article 102961"},"PeriodicalIF":4.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chloe Cheah , Callan Lavery , Andrew R. Johnson , Patrick J.F. Clarke , Matthew P. Hyett , Peter M. McEvoy
{"title":"Changes and persistence in heart rate variability before and during social stress: A comparison of individuals with and without social anxiety disorder","authors":"Chloe Cheah , Callan Lavery , Andrew R. Johnson , Patrick J.F. Clarke , Matthew P. Hyett , Peter M. McEvoy","doi":"10.1016/j.janxdis.2024.102960","DOIUrl":"10.1016/j.janxdis.2024.102960","url":null,"abstract":"<div><div>Individuals with social anxiety disorder (SAD) experience significant and persistent fear of social situations as they anticipate rejection, scrutiny, and embarrassment. Given that physiological reactions to social situations may shape emotional experience in SAD, understanding psychophysiological changes operating in SAD may be important to address this potentially key perpetuating factor. This study compared the patterns of change (via contrasts of estimated marginal means) and persistence (via autoregressive models) of two indices of heart rate variability (HRV; Root Mean Square of Successive Differences between normal heartbeats, and High-Frequency absolute units) as physiological measures of emotion regulation, between individuals with SAD (n = 94) and without (n = 59) using the Trier Social Stress Test phases (TSST). Results revealed that the SAD group increased their need to regulate their emotions (peak HRV) during the preparation (i.e., anticipation) phase, particularly among women, whereas HRV peaked for the non-SAD group during the social-evaluative context. The SAD group’s increase in HRV in the preparation phase, relative to non-SAD group, was the opposite of the hypothesised effect. The non-SAD group demonstrated no significant persistence of HRV between some TSST phases, whereas the SAD group showed significant persistence across all phases, however no between-group differences were found. These findings provide novel evidence of similarities and differences in HRV between individuals with and without SAD while anticipating and encountering social-evaluative contexts.</div></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":"110 ","pages":"Article 102960"},"PeriodicalIF":4.8,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Excessive avoidance bias towards uncertain faces in non-clinical social anxiety individuals","authors":"Yining Kou , Huili Xing , Ronglian Zheng , Yihan Wu , Shuqing Feng , Feng Zou , Meng Zhang","doi":"10.1016/j.janxdis.2024.102944","DOIUrl":"10.1016/j.janxdis.2024.102944","url":null,"abstract":"<div><div>Previous survey studies have consistently shown a strong link between social anxiety and intolerance for uncertainty. However, this association lacks empirical validation from laboratory investigations. To bridge this gap, we conducted a study utilizing the ultimatum game task to assign distinct social connotations (egoistic, altruistic, and uncertain) to three initially neutral faces. Subsequently, we utilized the Approach-Avoidance Task (AAT) paradigm to evaluate participants' approach-avoidance tendencies towards the faces with varying social meanings. Additionally, we collected data on participants' levels of social anxiety and trait anxiety. Our results indicate that both social anxiety and trait anxiety levels impact individuals' avoidance behaviors when faced with socially uncertain cues. This suggests that individuals with higher levels of social anxiety may demonstrate increased sensitivity to uncertainty in social contexts, leading to avoidance behaviors. Crucially, our findings directly underscore the heightened avoidance tendencies of non-clinical individuals with social anxiety towards socially uncertain stimuli, thereby providing new empirical support for research on anxiety disorders related to uncertainty.</div></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":"108 ","pages":"Article 102944"},"PeriodicalIF":4.8,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. H. Stanley Seah , Jennifer S. Silk , Erika E. Forbes , Cecile D. Ladouceur
{"title":"Negative emotion differentiation buffers against intergenerational risk for social anxiety in at-risk adolescent girls","authors":"T. H. Stanley Seah , Jennifer S. Silk , Erika E. Forbes , Cecile D. Ladouceur","doi":"10.1016/j.janxdis.2024.102942","DOIUrl":"10.1016/j.janxdis.2024.102942","url":null,"abstract":"<div><div>Social anxiety disorder (SAD) tends to emerge during adolescence and is more prevalent among those assigned female at birth. Parental social anxiety confers risk for adolescent SAD but less is known regarding protective factors. Research suggests that emotion differentiation (the ability to discriminate between similarly valenced emotions, e.g., fear vs. sadness vs. anger) may be protective, as it is associated with adaptive psychosocial outcomes. However, little work has examined how emotion differentiation influences the development of SAD, particularly during periods of higher risk such as adolescence. In a longitudinal study of adolescent girls at high temperamental risk for SAD (aged 11–14-years; <em>n</em>=114), we tested whether emotion differentiation (derived using negative and positive emotion ratings from 16-day ecological momentary assessments at baseline) moderated the relationship between parental and adolescent social anxiety symptoms across two years. Results revealed significant moderation by negative (but not positive) emotion differentiation (<em>p</em>=.042): Baseline parental social anxiety was positively associated with adolescent social anxiety symptoms at two-year follow-up but only at lower (vs. higher) levels of emotion differentiation, even after controlling for baseline depressive symptoms. Exploratory analyses showed that these effects were unique to avoidance of social situations (<em>p</em>=.014). Findings highlight the protective effects of emotion differentiation and have important clinical implications for understanding and treating SAD.</div></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":"108 ","pages":"Article 102942"},"PeriodicalIF":4.8,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jae-Min Kim , Hee-Ju Kang , Ju-Wan Kim , Ju-Yeon Lee , Hyunseok Jang , Jung-Chul Kim , Sung-Wan Kim , Il-Seon Shin
{"title":"Interplay of serum BDNF levels and childhood adversity in predicting earlier-onset post-traumatic stress disorder: A two-year longitudinal study","authors":"Jae-Min Kim , Hee-Ju Kang , Ju-Wan Kim , Ju-Yeon Lee , Hyunseok Jang , Jung-Chul Kim , Sung-Wan Kim , Il-Seon Shin","doi":"10.1016/j.janxdis.2024.102943","DOIUrl":"10.1016/j.janxdis.2024.102943","url":null,"abstract":"<div><div>This longitudinal study explored the intricate relationships between serum Brain-Derived Neurotrophic Factor (sBDNF) levels, exposure to childhood adversities, and the subsequent development of Post-Traumatic Stress Disorder (PTSD), distinguishing between earlier- and delayed-onset forms over a two-year follow-up period in individuals sustaining physical injuries. We recruited patients presenting with moderate to severe physical injuries at a trauma center, conducting baseline assessments of sBDNF levels and childhood adversities through the Adverse Childhood Experiences (ACE) questionnaire. Additionally, detailed socio-demographic and clinical data were compiled. The Clinician-Administered PTSD Scale for DSM-5 was employed to diagnose PTSD at 3, 6, 12, and 24 months post-injury. Binary and multinomial logistic regression analyses were applied to elucidate the interactions between sBDNF levels, childhood adversities, and PTSD onset patterns. Among 895 participants, PTSD was diagnosed in 107 individuals (11.9 %), with 76 (8.4 %) exhibiting symptoms indicative of earlier-onset PTSD and 31 (3.5 %) demonstrating delayed-onset PTSD. Significantly, lower sBDNF levels were associated with a higher risk of earlier-onset PTSD specifically in the context of childhood adversities. This association was not observed in individuals without childhood adversities or in those with delayed-onset PTSD. The findings suggest a complex and critical interplay between neurobiological factors, specifically sBDNF levels, and early life adversities in influencing the timing of PTSD onset, potentially deepening the understanding of PTSD etiology.</div></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":"108 ","pages":"Article 102943"},"PeriodicalIF":4.8,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Colin O.W. Ganzevoort , Lidewij H. Wolters , Rianne Hornstra , Caitlin M. Grieve , Davíð R.M.A. Højgaard , Gudmundur A. Skarphedinsson , Bernhard Weidle , Polly Waite , Lizél-Antoinette Bertie , Mark Tomlinson , Maaike H. Nauta
{"title":"Intensive treatments for children and adolescents with anxiety or obsessive-compulsive disorders: A systematic review and meta-analysis","authors":"Colin O.W. Ganzevoort , Lidewij H. Wolters , Rianne Hornstra , Caitlin M. Grieve , Davíð R.M.A. Højgaard , Gudmundur A. Skarphedinsson , Bernhard Weidle , Polly Waite , Lizél-Antoinette Bertie , Mark Tomlinson , Maaike H. Nauta","doi":"10.1016/j.janxdis.2024.102940","DOIUrl":"10.1016/j.janxdis.2024.102940","url":null,"abstract":"<div><div>Anxiety and obsessive-compulsive disorders have a significant negative impact on youth. Cognitive behavioural therapy (CBT) is recommended and established as effective first-step treatment, but persistent symptoms and non-response are common. Intensive psychological treatments deliver more or longer sessions over a shorter time span, with fewer session gaps. However, an understanding of their effectiveness, characteristics, acceptability, and feasibility is lacking. Systematically searching five databases yielded four controlled and 36 uncontrolled studies (<em>N</em>=2707) involving youth with primary anxiety or obsessive-compulsive disorders, many of whom received prior treatments. Intensive treatments were acceptable and feasible, with low drop-out rates. Between-group analyses compared intensive treatment with standard treatment (<em>k =</em> 2) or waitlist (<em>k =</em> 2), revealing no significant post-treatment differences in symptom severity or remission. Uncontrolled within-group analyses of intensive treatments showed large improvements from pre- to post-treatment in symptoms (<em>k</em> = 47), remission (<em>k</em> = 17), impairment (<em>k</em> = 22), functioning (<em>k</em> = 5), and quality of life (<em>k</em> = 2), with larger effects at follow-ups. Intensive treatments show promise for youth with anxiety or obsessive-compulsive disorders by potentially offering high treatment completion rates and comparable outcomes to standard CBT, aiding earlier recovery and reducing overall suffering. This systematic review/meta-analysis provides a comprehensive overview of intensive treatments, their theoretical considerations, and empirical findings. Future RCTs should compare the effectiveness of standard and intensive treatments and identify optimal populations for their use.</div></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":"108 ","pages":"Article 102940"},"PeriodicalIF":4.8,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}