Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv最新文献

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Changes in household composition and their effects on the academic achievement of orphans and vulnerable children affected by HIV in rural Zambia.
IF 1.2 4区 医学
Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv Pub Date : 2025-04-01 DOI: 10.1080/09540121.2025.2484633
Mei Tan, Nan Li, Ackim Mungo, Philip E Thuma, Elena L Grigorenko
{"title":"Changes in household composition and their effects on the academic achievement of orphans and vulnerable children affected by HIV in rural Zambia.","authors":"Mei Tan, Nan Li, Ackim Mungo, Philip E Thuma, Elena L Grigorenko","doi":"10.1080/09540121.2025.2484633","DOIUrl":"https://doi.org/10.1080/09540121.2025.2484633","url":null,"abstract":"<p><p>The African kinship system facilitates the movement of children and adults between households to mitigate hardship, yet few studies have documented membership changes in rural African households over time and addressed the effects of these household dynamics on the developmental outcomes of children. We used a household inventory instrument to document the number of changes in household membership experienced by 93 households in rural Zambia between two timepoints (∼2 years apart). We then used multilevel models to evaluate the effects of migration and household change on the academic learning of the children affected by HIV residing in these households, positing migration between households as a proxy for household connectivity and a potential protective factor for children. Our inventoried households experienced on average 4.12 changes in membership over the measured period. About half of these changes were due to children under 10 moving between relatives' households. No effects of these migration-related variables were found on children's academic progress at the family level. Household connectivity, as operationalized by the movement of individuals between households, may be typical to these children's home life and were not shown to be detrimental to their academic learning.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-12"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring determinants of pre-exposure prophylaxis awareness and willingness among sexual minority men in Taiwan: a stochastic search variable selection approach.
IF 1.2 4区 医学
Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv Pub Date : 2025-04-01 Epub Date: 2025-02-05 DOI: 10.1080/09540121.2025.2458628
Daniel Mayo, Poyao Huang
{"title":"Exploring determinants of pre-exposure prophylaxis awareness and willingness among sexual minority men in Taiwan: a stochastic search variable selection approach.","authors":"Daniel Mayo, Poyao Huang","doi":"10.1080/09540121.2025.2458628","DOIUrl":"10.1080/09540121.2025.2458628","url":null,"abstract":"<p><p>Since the introduction of pre-exposure prophylaxis (PrEP) in Taiwan in 2016, understanding factors influencing awareness and willingness among sexual minority men (SMM) remains critical. This study investigated predictors of PrEP awareness and willingness among SMM in Taiwan. A cross-sectional online survey conducted between April and May 2023 included 379 HIV-negative or status-unknown cisgender men identifying as gay, bisexual, or men who have sex with men, aged 18-59. Using stochastic search variable selection (SSVS), regression models identified key factors associated with PrEP awareness and willingness. Results revealed high awareness (96.9%) but moderate willingness (75.5%) to use PrEP. Regular HIV/STI testing, using apps to find sex partners, and community affinity significantly predicted both awareness and willingness. Additionally, internalized stigma, higher education, financial stress, and sexualized substance use were linked to awareness, while enacted stigma and PrEP awareness were associated with willingness. These findings highlight the need for targeted strategies to address stigma and barriers to awareness and willingness. Leveraging digital platforms and fostering community engagement are essential for strengthening these critical precursors in HIV prevention among SMM in Taiwan.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"588-597"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Storytelling sessions for PrEP/ART education and psychosocial support among expectant serodiscordant couples: results from a pilot feasibility trial in Zambézia Province, Mozambique.
IF 1.2 4区 医学
Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv Pub Date : 2025-03-29 DOI: 10.1080/09540121.2025.2482647
Caroline De Schacht, Hannah L Brooks, Erin Graves, Almiro Emílio, Ariano Matino, Taofik Oyekunle, Arifo Aboobacar, Carolyn M Audet
{"title":"Storytelling sessions for PrEP/ART education and psychosocial support among expectant serodiscordant couples: results from a pilot feasibility trial in Zambézia Province, Mozambique.","authors":"Caroline De Schacht, Hannah L Brooks, Erin Graves, Almiro Emílio, Ariano Matino, Taofik Oyekunle, Arifo Aboobacar, Carolyn M Audet","doi":"10.1080/09540121.2025.2482647","DOIUrl":"https://doi.org/10.1080/09540121.2025.2482647","url":null,"abstract":"<p><p>Pre-exposure prophylaxis (PrEP) is offered to pregnant HIV-uninfected women in serodiscordant relationships in Mozambique, yet uptake is still low. We conducted a randomized feasibility trial of PrEP education and psychosocial support to serodiscordant expectant couples via three storytelling sessions in two districts within Zambézia Province. Data were collected between December 2020 and December 2022. We recruited 64 couples (31 control and 33 intervention) from two health facilities. We assessed the intervention's effect on psychosocial metrics related to PrEP (stigma, treatment self-efficacy, treatment expectations, relationship satisfaction, social support), retention in clinical services, and participants' acceptability of each storytelling session. Among couples randomized to the intervention, 24 (73%) completed all three sessions. No impact was seen on median medication possession ratio (among women: 74.0% and 73.8% [<i>p</i> = 0.514]; among men: 78.3% and 75.4% [<i>p</i> = 0.543] for control and intervention groups, respectively). Surveys revealed no change in PrEP stigma, treatment self-efficacy, treatment expectations, or relationship satisfaction. In interviews, participants reported increased PrEP knowledge, improved trust, capacity, and motivation to remain adherent to their medications. Some described low PrEP awareness within their communities and suggested community-based educational sessions. In-person narrative-style storytelling could be an acceptable method of conveying PrEP information to serodiscordant couples in rural areas in Mozambique.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-11"},"PeriodicalIF":1.2,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HIV diagnosis in pregnancy: a yearn for psychosocial support amongst pregnant women.
IF 1.2 4区 医学
Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv Pub Date : 2025-03-28 DOI: 10.1080/09540121.2025.2482657
Eugene Musiiwa Makhavhu, Sister Vanessa Mahlangu, Andile Glodin Mokoena de-Beer
{"title":"HIV diagnosis in pregnancy: a yearn for psychosocial support amongst pregnant women.","authors":"Eugene Musiiwa Makhavhu, Sister Vanessa Mahlangu, Andile Glodin Mokoena de-Beer","doi":"10.1080/09540121.2025.2482657","DOIUrl":"https://doi.org/10.1080/09540121.2025.2482657","url":null,"abstract":"<p><p>Pregnancy can be associated with excitement at the thought of adding a new member to a family. Many occurrences may as well accompany it, some of which are expected physical changes. However, an HIV diagnosis while pregnant may hinder the psychosocial health outcome of the pregnant mother and affect her response to the pregnancy as a result of the HIV test. To that effect, the psychosocial needs of the pregnant mother post HIV-positive test must be catered for. This paper explored the psychosocial support needs of pregnant women diagnosed with HIV during pregnancy. A qualitative, exploratory, and descriptive design was followed. Data were collected using an interview guide from 20 purposefully sampled women at a clinic in the Thembisile-Hani district municipality. Five themes emerged and findings indicated the need for psychosocial support from groups, family and healthcare professionals. A lack of post-result counselling also emerged with the results. The study exposed gaps between what HIV-positive mothers require as support and what they receive from the healthcare facilities. This indicated the need to implement adequate post-testing education and counselling fit for the psychosocial needs of pregnant HIV-positive women.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-12"},"PeriodicalIF":1.2,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
People who inject drugs and men who have sex with men living with HIV in India experience low probability of viral rebound and high levels of persistent viremia during the first 12 months of antiretroviral therapy.
IF 1.2 4区 医学
Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv Pub Date : 2025-03-28 DOI: 10.1080/09540121.2025.2484635
Talia A Loeb, Sunil S Solomon, Mihili P Gunaratne, A K Srikrishnan, C K Vasudevan, Rifa T Khan, Santhanam Anand, Boobalan Jayaseelan, Muniratnam Suresh Kumar, David D Celentano, Gregory M Lucas, Shruti H Mehta, Allison M McFall
{"title":"People who inject drugs and men who have sex with men living with HIV in India experience low probability of viral rebound and high levels of persistent viremia during the first 12 months of antiretroviral therapy.","authors":"Talia A Loeb, Sunil S Solomon, Mihili P Gunaratne, A K Srikrishnan, C K Vasudevan, Rifa T Khan, Santhanam Anand, Boobalan Jayaseelan, Muniratnam Suresh Kumar, David D Celentano, Gregory M Lucas, Shruti H Mehta, Allison M McFall","doi":"10.1080/09540121.2025.2484635","DOIUrl":"https://doi.org/10.1080/09540121.2025.2484635","url":null,"abstract":"<p><p>People who inject drugs (PWID) and men who have sex with men (MSM) in India are disproportionately affected by HIV and experience challenges achieving sustained viral suppression. We evaluated probabilities of suppression over time and characteristics associated with persistent viremia and viral rebound among MSM and PWID living with HIV (PLHIV) using 12 months of data collected between 2017-2019 from a cluster-randomized trial across 16 cities in India. To assessprobabilities of suppression, we fit logistic transition models with generalized estimating equations. To assess correlates of persistent viremia and viral rebound, we fit multivariable multilevel logistic regression models. Of 750 PWID, 88% were male and 14% completed high school. Of 850 MSM, 29% completed high school and 54% were married. 46% of PWID and 67% of MSM maintained viral suppression once achieved. Probabilities of viral rebound decreased over time. The probability of newly achieving suppression decreased, from 33%-12% after six months among PWID and 60%-13% among MSM. Among PWID, correlates of persistent viremia included lower education, employment, homelessness, and active injection. Among MSM, hazardous alcohol use was associated with viremia and viral rebound. Treatment engagement and support efforts need to be intensified to encourage PLHIV to achieve life-long suppression.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-12"},"PeriodicalIF":1.2,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between frailty and low sexual function among sexually active older adults living with HIV in China: a multi-centre cross-sectional study in China. 中国艾滋病病毒感染者中性生活活跃的老年人身体虚弱与性功能低下之间的关系:一项在中国进行的多中心横断面研究。
IF 1.2 4区 医学
Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv Pub Date : 2025-03-28 DOI: 10.1080/09540121.2025.2480151
Bingyi Wang, Xin Peng, Yong Lu, Leiwen Fu, Xinyi Li, Zhen Lu, Tian Tian, Weijie Zhang, Xin Xiao, Lin Ouyang, Ying Wang, Maohe Yu, Guohui Wu, Yoshiko Sakuma, Yong Cai, Dan Wu, Weiming Tang, Joseph D Tucker, Huachun Zou
{"title":"Association between frailty and low sexual function among sexually active older adults living with HIV in China: a multi-centre cross-sectional study in China.","authors":"Bingyi Wang, Xin Peng, Yong Lu, Leiwen Fu, Xinyi Li, Zhen Lu, Tian Tian, Weijie Zhang, Xin Xiao, Lin Ouyang, Ying Wang, Maohe Yu, Guohui Wu, Yoshiko Sakuma, Yong Cai, Dan Wu, Weiming Tang, Joseph D Tucker, Huachun Zou","doi":"10.1080/09540121.2025.2480151","DOIUrl":"https://doi.org/10.1080/09540121.2025.2480151","url":null,"abstract":"<p><p>The expanding ageing population increases the importance of understanding frailty and related impacts on health. Our objectives were to examine the sexual function and its association with frailty among sexually active older adults aged 50+ living with HIV (OALHIV). A multi-centre cross-sectional study was conducted between September 2021 and July 2022. We enrolled OALHIV from specialized infectious disease hospitals providing HIV care in four cities in China. Data were collected through an investigator-administered questionnaire. Logistic regression was used to assess correlates of lower sexual function. 239 sexually active OALHIV (40 women and 199 men) were included in the present analyzes. 53 (22.2%) participants had frailty. About two-fifths (37.7%) reported at least one sexual difficulty lasting 3 months or more in the past year. Lack of interest in having sex was the most commonly reported sexual response problem (27.2%). 29.7% expressed satisfaction with their sex life. 49 participants were categorized as having a low sexual function. Frailty (aOR 3.03, 95%CI 1.22-7.53) was associated with low sexual function. OALHIV with frailty should be screened for sexual function problems. More efforts should be made to integrate sexual health services into geriatric services, ensuring comprehensive care that addresses their specific sexual concerns.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-12"},"PeriodicalIF":1.2,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"It empowered me to move my timeline forward": first person thematically analysed accounts of a novel behavioural intervention to support status-sharing in young adults with perinatally acquired HIV in UK and Uganda.
IF 1.2 4区 医学
Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv Pub Date : 2025-03-27 DOI: 10.1080/09540121.2025.2482672
Aoife O'Keeffe, Joseph Price, Janet Seeley, Georgina Gnan, Victor Musiime, Sarah Fidler, Graham Frize, Annette Uwizera, Caroline Foster, Michael Evangeli
{"title":"\"It empowered me to move my timeline forward\": first person thematically analysed accounts of a novel behavioural intervention to support status-sharing in young adults with perinatally acquired HIV in UK and Uganda.","authors":"Aoife O'Keeffe, Joseph Price, Janet Seeley, Georgina Gnan, Victor Musiime, Sarah Fidler, Graham Frize, Annette Uwizera, Caroline Foster, Michael Evangeli","doi":"10.1080/09540121.2025.2482672","DOIUrl":"https://doi.org/10.1080/09540121.2025.2482672","url":null,"abstract":"<p><p>Young adults living with perinatally acquired HIV (PAH) face many stressors. Sharing one's status may help with coping with these challenges but there are no rigorously evaluated interventions to support HIV status sharing in this population. The aim of this study was to explore the experiences of participants in a novel HIV status-sharing intervention guided by motivational interviewing. We used a cross-sectional, qualitative design. Ten young adults from Uganda (20-25 years; 6 female), nine from the UK (19-29 years; 7 female) and five therapists (2 UK; 3 Uganda) participated in individual semi-structured interviews. The data were analysed using thematic analysis. Seven theoretical themes were identified. Participants reported positive experiences of the intervention, a desire for more support and the importance of peer interaction. This study provides evidence for the acceptability of a novel HIV-sharing intervention for young adults with PAH. The intervention could inform HIV sharing guidance and clinical practice.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-12"},"PeriodicalIF":1.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Results of a workshop intervention trial to reduce HIV and intersectional stigma among sexual and gender minorities and healthcare workers in the Dominican Republic.
IF 1.2 4区 医学
Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv Pub Date : 2025-03-26 DOI: 10.1080/09540121.2025.2484311
Henna Budhwani, Jiaying Hao, Dustin M Long, John Waters, Nelson Varas-Díaz, Sylvie Naar, Laura Nyblade, Christyenne L Bond, Robert Paulino-Ramirez, Janet M Turan
{"title":"Results of a workshop intervention trial to reduce HIV and intersectional stigma among sexual and gender minorities and healthcare workers in the Dominican Republic.","authors":"Henna Budhwani, Jiaying Hao, Dustin M Long, John Waters, Nelson Varas-Díaz, Sylvie Naar, Laura Nyblade, Christyenne L Bond, Robert Paulino-Ramirez, Janet M Turan","doi":"10.1080/09540121.2025.2484311","DOIUrl":"https://doi.org/10.1080/09540121.2025.2484311","url":null,"abstract":"<p><p>Eliminating stigmas that harm sexual and gender minorities (SGM) with HIV is necessary to end the epidemic; however, few validated stigma-reducing interventions for healthcare settings exist, and even fewer have been evaluated in Spanish-speaking contexts. Finding Respect and Ending Stigma around HIV (FRESH) is a healthcare setting stigma-reduction intervention that was adapted and tested to address HIV and intersectional stigmas that harm SGM with HIV in the Dominican Republic. Herein, we detail the intervention adaptation process and present feasibility, acceptability, and pre-post preliminary effectiveness results ascertained via paired t-tests. Twenty healthcare workers at HIV clinics and sixteen SGM with HIV received the intervention (N = 36). Among healthcare workers, intervention receipt was associated with reductions in negative opinions about people with HIV (PWH, <i>p</i> = 0.01); among SGM PWH there were significant improvements in healthcare empowerment (<i>p</i> < 0.05) and awareness of clinic-based stigma (<i>p</i> < 0.05). Nearly 100% rated the intervention, content, or quality of information as excellent; 95% reported they would recommend FRESH to friends or colleagues. All participants felt the intervention helped them to \"better understand and deal with stigma.\" The Spanish-language FRESH intervention is a promising stigma-reducing intervention for SGM PWH and healthcare workers. Future directions include intervention full-scale testing in Spanish-language settings.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-9"},"PeriodicalIF":1.2,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Misconceptions and limited experience with HIV pre-exposure prophylaxis (PrEP) among fishermen in Western Kenya: a qualitative study.
IF 1.2 4区 医学
Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv Pub Date : 2025-03-25 DOI: 10.1080/09540121.2025.2480149
Phoebe Olugo, Holly Nishimura, Marguerite Thorp, Jayne Lewis-Kulzer, Bernard Ayieko, Kawango Agot, Zachary A Kwena, Carol S Camlin, Sarah A Gutin
{"title":"Misconceptions and limited experience with HIV pre-exposure prophylaxis (PrEP) among fishermen in Western Kenya: a qualitative study.","authors":"Phoebe Olugo, Holly Nishimura, Marguerite Thorp, Jayne Lewis-Kulzer, Bernard Ayieko, Kawango Agot, Zachary A Kwena, Carol S Camlin, Sarah A Gutin","doi":"10.1080/09540121.2025.2480149","DOIUrl":"https://doi.org/10.1080/09540121.2025.2480149","url":null,"abstract":"<p><p>Daily oral HIV pre-exposure prophylaxis (PrEP) is highly effective when taken consistently, but its uptake remains low among mobile fishermen in Kenya. This study explored barriers and facilitators to PrEP uptake in three Lake Victoria beach communities. In-depth interviews (IDIs) and focus group discussions (FGDs) were conducted with 65 fishermen, purposively sampled by community, age and study arm. IDIs and FGDs examined PrEP knowledge, perceptions and experiences and were conducted in Swahili or Dholuo, transcribed and translated into English. Data were analyzed using a framework approach. Most participants were >35 years old (56%), married (83%) and half (48%) had completed primary education or higher. Although most had heard of PrEP, some confused it with post-exposure prophylaxis, and many were unsure of correct dosing and eligibility. Barriers to uptake included anticipated partner conflict, confusion with HIV treatment medications and stigma associated with PrEP use, leading to fear of disclosing use to sexual partners. Facilitators included a preference for PrEP over condoms and its perceived protection in sero-different partnerships. Despite free availability in clinics, misconceptions may hinder uptake. Educational interventions are needed to improve PrEP knowledge and reduce stigma, especially among mobile populations like fishermen.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-10"},"PeriodicalIF":1.2,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HIV pre-exposure prophylaxis uptake and associated factors among HIV serodiscordant heterosexual couples in Nairobi City County, Kenya.
IF 1.2 4区 医学
Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv Pub Date : 2025-03-24 DOI: 10.1080/09540121.2025.2480156
Gladys Nyapera, Rosebella A Iseme, Raphael O Ondondo
{"title":"HIV pre-exposure prophylaxis uptake and associated factors among HIV serodiscordant heterosexual couples in Nairobi City County, Kenya.","authors":"Gladys Nyapera, Rosebella A Iseme, Raphael O Ondondo","doi":"10.1080/09540121.2025.2480156","DOIUrl":"https://doi.org/10.1080/09540121.2025.2480156","url":null,"abstract":"<p><p>HIV antiretroviral drugs used as pre-exposure prophylaxis (PrEP) are effective for HIV prevention. This study evaluated determinants of PrEP uptake among HIV-negative spouses in HIV-serodiscordant heterosexual relationships in Nairobi City County, Kenya. Of the 424 participants, 114 reported current PrEP use, resulting in a PrEP uptake of 27% (23-31%). The top reason for current PrEP use was to achieve pregnancy (<i>n</i> = 69; 61%). Of the 424 participants, 209 (49%) had never used PrEP, and the leading reasons for never using PrEP were lack of PrEP information (38%) and self-perceived low risk for HIV (36%). Factors associated with decreased likelihood of PrEP use included: low level of education (<i>p</i> = 0.026), self-perception of being at low-to-no risk for HIV (<i>p</i> = 0.021), lack of desire for more children (<i>p</i> = 0.005) and lack of knowledge that PrEP is offered free (<i>p</i> = 0.004). Female sex (aOR = 2.3; 95% CI: 1.4-4.0) and lack of condom use (aOR = 2.5; 95% CI: 1.4-4.5) were associated with increased odds of taking PrEP. Uptake of PrEP among HIV-serodiscordant couples in Nairobi City County was low, and PrEP use was driven by desire to fulfill pregnancy intentions. Aggressive educational campaigns to address self-HIV-risk perceptions and increase PrEP knowledge are necessary for increased PrEP demand.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-10"},"PeriodicalIF":1.2,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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